CN109364128A - A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain - Google Patents
A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of transdermal cream of herbal mixture and preparation method thereof for treating calcaneal spur and heel numbness pain.Raw material includes: 15-20 parts of Radix Clematidis extract by weight, 13-18 parts of Ramulus Cinnamomi extract, 9-13 parts of extractive of pubescent angelica root coumarin, 9-13 parts of Herba Siegesbeckiae extract, 9-13 parts of Herba speranskiae tuberculatae extract, 9-13 parts of Radix Gentianae Macrophyllae extract, 8-12 parts of Radix Stephaniae Tetrandrae extract, 8-12 parts of Radix Saposhnikoviae extract.The effect of present invention plays activating microcirculation and removing stasis medicinal by all medicines altogether, soft or hard dissipating bind, eliminating dampness and dredging channels, anti-inflammatory analgetic reaches treatment calcaneal spur and heel numbness pain purpose.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of to treat calcaneal spur and the herbal mixture of heel numbness pain is saturating
Skin cream and preparation method thereof.
Background technique
Spur, medically known as bone wart (Bone Spur), it was both non-fully made of bone, also not sharp as pierced, and was
Osteoproliferation is commonly called as.Spur is osteo-articular tissues first is that primary, with the increase at age, limbs joint and acral,
Poor blood circulation, microcirculation disorder, nutritional deficiency required for leading to muscle or organizing, metabolic imbalance accelerate muscles and bones old
Change, is stiff, and retrogression occurs, leading to osteoproliferation, and forming bone wart.Second is that physically weak, defensive Qi instability, the flesh natural fibre line of meat, which loses, to be closed, and is trembled with fear
It is wet enter in, coagulate and form numbness, then joint dystrophy deformity, damage, inflammation can also cause hyperplasia in self-healing, and vascular compression nerve can be led
Cause foot's severe pain, difficulty in walking.It causes the abrasion of cartilage third is that heel is moved for a long time and born a heavy burden, destroy, and facilitating bone
Repairing, hardening and compensatory hypertrophy, the protrusion of itself.Majority cause synovial bursa aseptic inflammation to be made because of the long spur of heel
At pain or drawing periosteum on plantar fascia caused by under calcaneum region talagia.
Modern Western medicine treatment method mostly uses greatly immune formulation, hormone and anti-inflammation and analgesic drugs, these drugs are first is that secondary make
With big, especially hormone has dependence, once using being substantially difficult to deactivate, these drug effects early period are obvious, later period effect
Fruit is all more weak, can only escalated dose control the state of an illness, it is very big to the harm of body, in ineffective situation of taking medicine, only
It well by means of operation, but operates on and only the spur on surface is cut off, still will continue to grow after a time.Chinese medicine is living with relaxing muscles and tendons
Blood, warming channel and expelling cold, dispelling wind and eliminating dampness promote local blood circulation, improve surrounding tissue nutrition, repair osteopathy tissue, softening hard masses, blunt
Change spur, to reach anti-inflammatory, swelling and pain relieving purpose.By outer patch transdermal administration, affected part is made to reach higher drug effect object
Matter concentration is had one's ideas straightened out deep, realizes the target of fundamentally treatment.
Summary of the invention
The purpose of the present invention is to provide a kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain and its systems
Preparation Method.Activating microcirculation and removing stasis medicinal is played altogether by all medicines, the effect of soft or hard dissipating bind, eliminating dampness and dredging channels, anti-inflammatory analgetic, reaches treatment calcaneal spur
With heel numbness pain purpose.
To achieve the above object, the present invention adopts the following technical scheme:
A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, raw material includes: that by weight, the root of Chinese clematis mentions
15-20 parts of object are taken, 13-18 parts of Ramulus Cinnamomi extract, 9-13 parts of extractive of pubescent angelica root coumarin, 9-13 parts of Herba Siegesbeckiae extract, lopseed is extracted
9-13 parts of object, 9-13 parts of Radix Gentianae Macrophyllae extract, 8-12 parts of Radix Stephaniae Tetrandrae extract, 8-12 parts of Radix Saposhnikoviae extract.
A kind of preparation method of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, including following step
It is rapid:
(1) preparation forms: taking said extracted object, is mixed according to the above mentioned proportion, transdermal enhancer (peppermint oil+azone, the two is added
Mass ratio 1/3), tackifier (rosin tree lipidol) by weight with the solid-liquid ratio of 1 ︰ 2 be first dissolved in temperature be 40~50 DEG C,
In the lysate be made of alcohol and glycerol, 40~50 DEG C are kept the temperature later；Coating fluid is made；The wherein volume ratio of alcohol and glycerol
For 7:3；Wherein transdermal enhancer accounts for the 2-5% of composition of raw materials constituent mass summation, and tackifier account for composition of raw materials constituent mass summation
3-5%；
(2) it is coated with: coating fluid being coated on silication fluorine carbon polyester film under heat-retaining condition and forms drug storing layer, then 30~40 DEG C
It is dry, 15~30min；
(3) it covers: after dry, back sheet being covered on the drug storing layer after drying；
(4) it is punched: being punched into suitable size to get the transdermal cream of herbal mixture for the treatment of calcaneal spur and heel numbness pain.
The root of Chinese clematis has wind-damp dispelling, the effect of degrading the channel.For rheumatic arthralgia, extremity numbness, muscle arteries and veins contraction is bent and stretched not
Benefit.Modern pharmacological research, the root of Chinese clematis have analgesia, cholagogue, antibacterial action, have emollescence to spur, and make meromyarian dried meat floss
It relaxes, spur is promoted to fall off, treatment osteoproliferation effect is than more significant.It can be clinically used for treatment of arthritis, talagia.Osmanthus
Branch, pungent-warm, energy warming meridians and promoting circulation of qi are apt to cold-dispelling, effective to cold-damp rheumatic arthralgia.Radix Angelicae Pubescentis, property pungent-warm is bitter, sweet, returns kidney, wing
Guang warp.Benefaction blood system, dispelling wind and eliminating dampness, arthritis analgesic.Radix saposhnikoviae, acrid flavour, sweet, slightly warm in nature.Return bladder, lung, spleen, Liver Channel.There is wind-dispelling
The effect of inducing diaphoresis, expel endogenous wind to relieve convulsion, relieving convulsion.Radix Stephaniae Tetrandrae has inducing diuresis for removing edema, wind-expelling pain-stopping effect.It is exclusively used in lower limb rheumatism, weight in wet base
Yu Fengzhe.Gentianae macrophyllae, it is pungent, bitter, it puts down.Return stomach, liver, gallbladder channel, be treat rheumatic arthritis one of main ingredient, wind-damp dispelling, clearing away damp-heat, only
Numbness pain.Herba Siegesbeckiae is worked hard slightly cold, and liver, the heart channel of Hang-Shaoyin are entered.Can wind-damp dispelling, degrading the channel, removing toxic substances, be used for rheumatic arthralgia, arthralgia and myalgia.Thoroughly
Bone grass is Euphorbiaceae speranskia tuberculata herb.With dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, eliminating stasis to subdue swelling, the effect of relieving pain of detoxifying.
Remarkable advantage of the invention is:
The present invention is using the root of Chinese clematis as monarch drug in a prescription, and Radix Angelicae Pubescentis, Herba Siegesbeckiae, lopseed are that minister is auxiliary, relaxing tendons and activating collaterals, dispelling wind and eliminating dampness dredging collateral, with osmanthus
Branch warming meridians and promoting circulation of qi, expelling wind and clearing away cold promote local blood circulation, improve surrounding tissue nutrition, repair osteopathy tissue；With Radix Stephaniae Tetrandrae,
Radix saposhnikoviae, gentianae macrophyllae inducing diuresis for removing edema, wet clearly to reduce phlegm and internal heat, relieving spasm and pain；Reasonable with compatibility, inner disease outer treat not only improves histotrophic nutrition, but also repairs
Multiple injury tissue, dispelling wind and eliminating dampness, warming channel and expelling cold and relieving spasm and pain multiple target effect effect.
Specific embodiment
Further to disclose rather than the present invention is limited, the present invention is described in further detail below in conjunction with example.
Embodiment 1
A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, raw material includes: that by weight, the root of Chinese clematis mentions
15 parts of object are taken, 13 parts of Ramulus Cinnamomi extract, 9 parts of extractive of pubescent angelica root coumarin, 9 parts of Herba Siegesbeckiae extract, 9 parts of Herba speranskiae tuberculatae extract, gentianae macrophyllae mentions
Take 9 parts of object, 8 parts of Radix Stephaniae Tetrandrae extract, 8 parts of Radix Saposhnikoviae extract.
A kind of preparation method of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, including following step
It is rapid:
(1) preparation forms: taking said extracted object, is mixed according to the above mentioned proportion, transdermal enhancer (peppermint oil+azone, the two is added
Mass ratio 1/3), tackifier (rosin tree lipidol) are first dissolved in temperature for 40 DEG C, by wine with the solid-liquid ratio of 1 ︰ 2 by weight
In the lysate of essence and glycerol composition, 50 DEG C are kept the temperature later；Coating fluid is made；Wherein the volume ratio of alcohol and glycerol is 7:3；Its
Middle transdermal enhancer accounts for the 2-5% of composition of raw materials constituent mass summation, and tackifier account for the 3-5% of composition of raw materials constituent mass summation；
(2) it is coated with: coating fluid being coated on silication fluorine carbon polyester film under heat-retaining condition and forms drug storing layer, then do for 30 DEG C
It is dry, 15min；
(3) it covers: after dry, back sheet being covered on the drug storing layer after drying；
(4) it is punched: being punched into suitable size to get the transdermal cream of herbal mixture for the treatment of calcaneal spur and heel numbness pain.
Embodiment 2
A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, raw material includes: that by weight, the root of Chinese clematis mentions
Take 18 parts of object, 15 parts of Ramulus Cinnamomi extract, 11 parts of extractive of pubescent angelica root coumarin, 11 parts of Herba Siegesbeckiae extract, 11 parts of Herba speranskiae tuberculatae extract, the Qin
11 parts of Macrophylla extract, 10 parts of Radix Stephaniae Tetrandrae extract, 10 parts of Radix Saposhnikoviae extract.
A kind of preparation method of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, including following step
It is rapid:
(1) preparation forms: taking said extracted object, is mixed according to the above mentioned proportion, transdermal enhancer (peppermint oil+azone, the two is added
Mass ratio 1/3) 2-5%, tackifier (rosin tree lipidol) 3-5%, being first dissolved in temperature by weight with the solid-liquid ratio of 1 ︰ 2 is
40 DEG C, in the lysate be made of alcohol and glycerol, 40 DEG C are kept the temperature later；Coating fluid is made；The wherein volume of alcohol and glycerol
Than for 7:3；Wherein transdermal enhancer accounts for the 2-5% of composition of raw materials constituent mass summation, and it is total that tackifier account for composition of raw materials constituent mass
The 3-5% of sum；
(2) it is coated with: coating fluid being coated on silication fluorine carbon polyester film under heat-retaining condition and forms drug storing layer, then do for 30 DEG C
It is dry, 20min；
(3) it covers: after dry, back sheet being covered on the drug storing layer after drying；
(4) it is punched: being punched into suitable size to get the transdermal cream of herbal mixture for the treatment of calcaneal spur and heel numbness pain.
Embodiment 3
A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, raw material includes: that by weight, the root of Chinese clematis mentions
Take 20 parts of object, 18 parts of Ramulus Cinnamomi extract, 13 parts of extractive of pubescent angelica root coumarin, 13 parts of Herba Siegesbeckiae extract, 13 parts of Herba speranskiae tuberculatae extract, the Qin
13 parts of Macrophylla extract, 12 parts of Radix Stephaniae Tetrandrae extract, 12 parts of Radix Saposhnikoviae extract.
A kind of preparation method of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, including following step
It is rapid:
(1) preparation forms: taking said extracted object, is mixed according to the above mentioned proportion, transdermal enhancer (peppermint oil+azone, the two is added
Mass ratio 1/3), tackifier (rosin tree lipidol) are first dissolved in temperature for 50 DEG C, by wine with the solid-liquid ratio of 1 ︰ 2 by weight
In the lysate of essence and glycerol composition, 50 DEG C are kept the temperature later；Coating fluid is made；Wherein the volume ratio of alcohol and glycerol is 7:3；Its
Middle transdermal enhancer accounts for the 2-5% of composition of raw materials constituent mass summation, and tackifier account for the 3-5% of composition of raw materials constituent mass summation；
(2) it is coated with: coating fluid being coated on silication fluorine carbon polyester film under heat-retaining condition and forms drug storing layer, then do for 40 DEG C
It is dry, 30min；
(3) it covers: after dry, back sheet being covered on the drug storing layer after drying；
(4) it is punched: being punched into suitable size to get the transdermal cream of herbal mixture for the treatment of calcaneal spur and heel numbness pain.
Efficacy experiment:
It confirms to make a definite diagnosis calcaneal spur disease patient 40 with spur at root bone tubercle by x ray photograph, wherein male 30,
Female 10；Age 50-60 years old, all patients diagnosed were randomly divided into test group (20) and control group (10), and two groups of patients exist
Gender, age, the course of disease, incidence etc. no significant difference, are comparable.
Test group patient treats with the following method: paste of the present invention being affixed on heel, is pasted within 12 hours one.
Control group patient smokes heel portion using steam, is then coated with commercially available heel patch, pastes within 12 hours one.
After treating a course for the treatment of, efficacy evaluation is carried out by following standard:
Cure: local symptom disappears, and walking is normal, and spur atrophy or barbed end are round and smooth.
It is effective: localized relief or basic disappearance, the obvious atrophy of spur.
Effective: local pain mitigates, and walking has the pain sensation.
Invalid: pretherapy and post-treatment symptom is without change.
Treatment results: for two groups of patients after treating, test group total effective rate is 95.80%, and control group total effective rate is
40.19%, test group total effective rate is apparently higher than control group.
The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, is all covered by the present invention.
Claims (5)
1. a kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain, it is characterised in that: raw material includes: by weight
Meter, 15-20 parts of Radix Clematidis extract, 13-18 parts of Ramulus Cinnamomi extract, 9-13 parts of extractive of pubescent angelica root coumarin, Herba Siegesbeckiae extract 9-13
Part, 9-13 parts of Herba speranskiae tuberculatae extract, 9-13 parts of Radix Gentianae Macrophyllae extract, 8-12 parts of Radix Stephaniae Tetrandrae extract, 8-12 parts of Radix Saposhnikoviae extract.
2. a kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain according to claim 1, feature exist
In: raw material include: 18 parts of Radix Clematidis extract by weight, 15 parts of Ramulus Cinnamomi extract, 11 parts of extractive of pubescent angelica root coumarin, Herba Siegesbeckiae
11 parts of extract, 11 parts of Herba speranskiae tuberculatae extract, 11 parts of Radix Gentianae Macrophyllae extract, 10 parts of Radix Stephaniae Tetrandrae extract, 10 parts of Radix Saposhnikoviae extract.
3. a kind of prepare a kind of side for the transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain as described in claim 1
Method, it is characterised in that: the following steps are included:
(1) preparation forms: taking composition of raw materials component proportionally to mix, transdermal enhancer 2-5%, tackifier 3-5% is added, by weight
Amount part meter is first dissolved in the lysate of preparation with the solid-liquid ratio of 1 ︰ 2, keeps the temperature 40~50 DEG C later；Coating fluid is made；Wherein thoroughly
Skin promotor accounts for the 2-5% of composition of raw materials constituent mass summation, and tackifier account for the 3-5% of composition of raw materials constituent mass summation；
(2) it is coated with: coating fluid being coated on silication fluorine carbon polyester film under heat-retaining condition and forms drug storing layer, then 30~40 DEG C
It is dry, 15~30min；
(3) it covers: after dry, back sheet being covered on the drug storing layer after drying；
(4) it is punched: being punched into suitable size to get the transdermal cream of herbal mixture for the treatment of calcaneal spur and heel numbness pain.
4. a kind of preparation side of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain according to claim 3
Method, it is characterised in that: the transdermal enhancer is that peppermint oil is mixed with azone according to mass ratio 1:3；The tackifier are rosin
Resinol.
5. a kind of preparation side of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain according to claim 3
Method, it is characterised in that: it is that 7:3 is formed that the lysate is by alcohol and glycerol by volume, and temperature is 40~50 DEG C.
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| CN201811317451.2A CN109364128A (en) | 2018-11-07 | 2018-11-07 | A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain |
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| CN201811317451.2A CN109364128A (en) | 2018-11-07 | 2018-11-07 | A kind of transdermal cream of herbal mixture for treating calcaneal spur and heel numbness pain |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526679A (en) * | 2012-02-08 | 2012-07-04 | 尹燕 | Chinese medicinal composition for treating calcaneal spur |
| CN104740022A (en) * | 2013-12-30 | 2015-07-01 | 魏修彦 | A method of treating heel pain |
-
2018
- 2018-11-07 CN CN201811317451.2A patent/CN109364128A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526679A (en) * | 2012-02-08 | 2012-07-04 | 尹燕 | Chinese medicinal composition for treating calcaneal spur |
| CN104740022A (en) * | 2013-12-30 | 2015-07-01 | 魏修彦 | A method of treating heel pain |
Non-Patent Citations (1)
| Title |
|---|
| 尹有学: "薰浴法在外伤科临床应用举隅", 《四川中医》 * |
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