CN115671237A - Formula of external ointment for traumatic injury and preparation method thereof - Google Patents

Formula of external ointment for traumatic injury and preparation method thereof Download PDF

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CN115671237A
CN115671237A CN202211397286.2A CN202211397286A CN115671237A CN 115671237 A CN115671237 A CN 115671237A CN 202211397286 A CN202211397286 A CN 202211397286A CN 115671237 A CN115671237 A CN 115671237A
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traumatic injury
formula
external ointment
preparation
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翟思程
魏萌
余涛
王娟
陈春梅
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

A traumatic injury topical unguent formula and its preparation method, the traumatic injury topical unguent formula comprises Olibanum, myrrha, rhizoma corydalis, radix et rhizoma Rhei, lignum sappan, notoginseng radix, radix Angelicae sinensis, rhizoma Drynariae, radix Dipsaci, caulis Spatholobi, curcuma rhizome, diclofenac sodium, laurocapram; the invention effectively solves the problems of long treatment period, unobvious drug effect, side effect and the like of common drugs in the treatment of traumatic injuries.

Description

Formula of external ointment for traumatic injury and preparation method thereof
Technical Field
The invention relates to the technical field of paste formulations and preparation methods thereof, in particular to an external paste formulation for traumatic injury and a preparation method thereof.
Background
In daily life activities, people cannot avoid the injuries from falls, such as bruising and bruising under the skin of the body, swelling and pain caused by sports sprain, collision of external appliances to the human body and the like; seriously affects the daily life of people, even falls down to the disease root, and the pain can recur from time to time; when treating diseases such as traumatic injuries, the traditional Chinese medicine composition is generally an oral medicine and an external application medicine, wherein the oral medicine is quickly absorbed when being taken, but can increase the gastrointestinal burden of a patient, and particularly western medicines can seriously affect the liver and kidney functions of a human body; compared with the external application medicine, the external application medicine is much safer, some doctors can choose to boil the medicine into common plaster and paste the plaster on the affected part in the treatment process, but the absorption is slow, and if the medicine compatibility is not proper, the effect is slow; some doctors can choose to boil the Chinese patent medicine into water and apply the Chinese patent medicine to the affected part in a hot compress way, so the Chinese patent medicine is well absorbed, but the duration time is short, and the operation is time-consuming and labor-consuming; in order to solve the above problems, there is a strong need for an external ointment formulation for traumatic injury, which is rapidly absorbed and has a long duration of drug action.
Disclosure of Invention
The invention provides an external ointment formula for treating traumatic injury and a preparation method thereof, aiming at the defects of the prior art when treating traumatic injury, and effectively solving the problems of long treatment period, unobvious drug effect, side effect and the like when common drugs are used for treating traumatic injury.
In order to solve the problems, the invention adopts the technical scheme that:
a formula of an external ointment for treating traumatic injury comprises Olibanum, myrrha, rhizoma corydalis, radix et rhizoma Rhei, lignum sappan, notoginseng radix, radix Angelicae sinensis, rhizoma Drynariae, radix Dipsaci, caulis Spatholobi, curcuma rhizome, diclofenac sodium, and laurocapram.
Preferably, the external traumatic injury ointment has the following formula: 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rhubarb, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi, 10 parts of turmeric, 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram.
A preparation method of an externally used paste for traumatic injury is characterized by comprising the following steps: the preparation method of the external ointment for traumatic injury comprises the following steps:
step 1: the preparation method comprises the following steps of (1) well taking 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rheum officinale, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi and 10 parts of turmeric, and then grinding the medicines into powder in a grinding machine;
step 2: sieving to remove residue after pulverizing, and soaking the sieved powder in wine for one week;
and step 3: adding Mel into the soaked medicinal powder, and decocting to viscous state;
and 4, step 4: and (3) cooling the medicine boiled in the step (3), adding 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram, and uniformly mixing.
Preferably, the external plaster for treating traumatic injury has the effects of promoting blood circulation to remove blood stasis, activating meridians to stop pain, and relieving swelling and promoting granulation.
Compared with the existing formula, the formula of the external ointment for treating traumatic injury has the following advantages:
the external use paste for traumatic injury is used for treating traumatic injury, and has the effects of promoting blood circulation, removing blood stasis, relieving pain, eliminating swelling and promoting granulation; in the process of compatibility, the medicines are reasonably not matched by adopting the compatibility principle of monarch, minister, assistant and guide according to the property and functions of the medicines, and the dosage is accurate; the traditional Chinese medicines supplement each other to achieve an ideal disease treatment effect; in addition, in the process of preparing the paste, diclofenac sodium and 2 percent of laurocapram are skillfully utilized, so that the capability of the affected skin of a patient for absorbing the drug effect is improved, and the treatment effect is enhanced; the ointment is directly applied to the skin of the affected part without other auxiliary operations during treatment, thereby saving the treatment time and avoiding the side effects caused by oral administration.
Drawings
Fig. 1 is a flow chart of the preparation of the external plaster for traumatic injury according to the formula and the preparation method of the external plaster for traumatic injury of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be further described with reference to the following specific embodiments of the present invention and with reference to the accompanying drawings, but the present invention is not limited to these embodiments.
The invention provides an external use ointment formula for traumatic injury and a preparation method thereof:
a formula of an external paste for traumatic injury comprises Olibanum, myrrha, rhizoma corydalis, radix et rhizoma Rhei, lignum sappan, notoginseng radix, radix Angelicae sinensis, rhizoma Drynariae, radix Dipsaci, caulis Spatholobi, curcuma rhizome, diclofenac sodium, and laurocapram.
The external ointment for traumatic injury comprises the following medicinal components in part by weight: 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rhubarb, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi, 10 parts of turmeric, 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram.
A preparation method of an external ointment for traumatic injury comprises the following steps:
step 1: the preparation method comprises the following steps of (1) well taking 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rheum officinale, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi and 10 parts of turmeric, and then grinding the medicines into powder in a grinding machine;
step 2: sieving to remove residue after pulverizing, and soaking the sieved powder in wine for one week;
and step 3: adding Mel into the soaked medicinal powder, and decocting to viscous state;
and 4, step 4: and (3) cooling the medicine boiled in the step (3), adding 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram, and uniformly mixing.
The invention is further described by the pharmaceutical analysis of each component in the formula of the external plaster for traumatic injury.
Frankincense: bitter taste and warm nature, entering heart, liver and spleen meridians, mainly has the effects of promoting blood circulation and qi circulation, stimulating menstrual flow and relieving pain, and detumescence and promoting granulation, and is often used in combination with myrrh;
myrrh: bitter taste, heart, liver and spleen meridians entered, and has the main effects of promoting blood circulation, relieving pain, removing blood stasis, eliminating swelling and promoting granulation; the traditional Chinese medicine composition is clinically used for treating hematoma and blood stasis caused by traumatic injury;
rhizoma corydalis: bitter taste and warm nature, which enter heart, liver and spleen channels, and have the main effects of promoting qi and blood circulation and relieving pain;
rhubarb: the medicine is bitter in taste and cold in nature, enters spleen channels, stomach channels and large intestine channels, has the main effects of clearing heat, removing stasis and stimulating the menstrual flow, and is clinically used for diseases such as traumatic injury, burn and the like;
sappan wood: sweet in flavor, entering heart and liver meridians; is mainly used for traumatic injury, fracture, tendon injury, stasis and swelling pain;
in the formula of the external ointment for traumatic injury, the five traditional Chinese medicines are used as monarch medicines for treating traumatic injury, and have the effects of removing blood stasis, relieving pain, reducing swelling and promoting tissue regeneration.
Pseudo-ginseng: tianqi, warm in nature, sweet and slightly bitter in taste, enters liver, stomach and large intestine meridians; has hemostatic, blood stasis dispelling, and analgesic effects;
chinese angelica: sweet taste and warm nature, and belongs to liver, heart and spleen channels, and has the effects of tonifying qi and nourishing blood;
in the formula of the external ointment for traumatic injury, the two traditional Chinese medicines are used as ministerial medicines for promoting blood circulation, removing blood stasis, dredging collaterals and relieving pain.
Rhizoma drynariae: bitter taste and warm nature, enter kidney and liver channel, and have effects of invigorating kidney, strengthening bone, and treating fracture; it can be used for treating fracture injury, blood stasis, and swelling and pain by clinically mixing with radix Dipsaci, olibanum, myrrha, etc.;
teasel root: bitter in taste, entering liver and kidney meridians; the main effects are tonifying liver and kidney, strengthening bones and muscles; the wine is clinically used for treating traumatic fracture, wherein the effect of the wine on teasel root is better;
in the formula of the external ointment for traumatic injury, the two traditional Chinese medicines are used as adjuvant medicines for nourishing liver and kidney, strengthening tendons and bones, relaxing tendons and activating collaterals.
Caulis spatholobi: the bitter and slightly sweet taste, which belongs to liver, heart and kidney channels, has the effects of promoting blood circulation, relaxing muscles and tendons, nourishing blood and regulating menstruation;
turmeric: bitter taste, spleen and liver meridian entered, and has the main effects of breaking blood and promoting qi circulation, and dredging channels and relieving pain;
in the formula of the external ointment for traumatic injury, the two traditional Chinese medicines are used as guiding medicines for introducing medicines into channels, dredging collaterals and relieving pain.
Diclofenac sodium belongs to non-steroidal anti-inflammatory drugs and is used for relieving pain in the formula of the external paste for traumatic injury.
Laurocapram and a non-polar transdermal enhancer, can soften cutin, enhance permeability, enable the drug to penetrate through skin barrier, and improve local or systemic blood concentration; the external use ointment formula for traumatic injury is used for increasing the permeability of the skin of a patient and promoting the skin of the patient to absorb other medicines.
The preparation method of the external ointment for treating traumatic injury also comprises adding Mel which is cool in nature and can clear heat; when the food is cooked, the food is warm in nature and can tonify the middle; sweet in flavor can remove toxicity, soft and moisten dryness; has effects in relieving spasm and pain, and harmonizing drug properties; the external ointment for traumatic injury is decocted to play a role in harmonizing other medicinal properties.
Example 1
As shown in figure 1: the preparation method comprises the following steps of (1) well taking 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rheum officinale, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi and 10 parts of turmeric, and then grinding the medicines into powder in a grinding machine; sieving to remove residue after pulverizing, and soaking sieved powder in wine for one week; adding honey into the soaked medicinal powder, boiling to be viscous, cooling the boiled medicine, adding a proper amount of 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram, and uniformly mixing.
Example 2
During specific treatment, the compound preparation is combined with the repeated diagnosis conditions of a large number of patients to make a medicine effect judgment: the external ointment for traumatic injury is smeared on the skin of an affected part of a patient, joint sprain of common ankle joints, knee joints, elbow joints, wrist joints and the like can relieve swelling and pain for about three days, the joint sprain can recover 50% in one week, the joint sprain can be completely cured in ten to fifteen days, the traumatic injury of the joints of common fingers and toes and the like can relieve swelling and pain in one day, and the joint sprain can be completely cured in five to ten days.
The specific embodiments described herein are merely illustrative of the spirit of the invention. Various modifications or additions may be made to the described embodiments or alternatives may be employed by those skilled in the art without departing from the spirit or ambit of the invention as defined in the appended claims.

Claims (3)

1. The formula of the external ointment for treating the traumatic injury is characterized in that: the external ointment formula for traumatic injury comprises frankincense, myrrh, rhizoma corydalis, rheum officinale, sappan wood, pseudo-ginseng, angelica sinensis, rhizoma drynariae, teasel root, caulis spatholobi, turmeric, diclofenac sodium and laurocapram.
2. The external ointment formula for traumatic injury of claim 1, which is characterized in that: the external ointment for traumatic injury comprises the following medicinal components in part by weight: 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rhubarb, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi, 10 parts of turmeric, 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram.
3. A method for preparing an external ointment for traumatic injury is characterized in that: the preparation method of the external ointment for traumatic injury comprises the following steps:
step 1: the preparation method comprises the following steps of (1) well taking 6 parts of frankincense, 6 parts of myrrh, 30 parts of corydalis tuber, 10 parts of rheum officinale, 15 parts of sappan wood, 10 parts of pseudo-ginseng, 15 parts of angelica, 30 parts of rhizoma drynariae, 25 parts of teasel root, 30 parts of caulis spatholobi and 10 parts of turmeric, and then grinding the medicines into powder in a grinding machine;
step 2: sieving to remove residue after pulverizing, and soaking sieved powder in wine for one week;
and step 3: adding Mel into the soaked medicinal powder, and decocting to viscous state;
and 4, step 4: and (3) cooling the medicine boiled in the step (3), adding 10-15 parts of diclofenac sodium and 3.74 parts of laurocapram, and uniformly mixing.
CN202211397286.2A 2022-11-09 2022-11-09 Formula of external ointment for traumatic injury and preparation method thereof Pending CN115671237A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983977A (en) * 2015-06-17 2015-10-21 曾德锋 Externally-applied drug for treating traumatic injuries and preparing method thereof
CN111617172A (en) * 2020-05-22 2020-09-04 陈玉瑞 A topical Chinese medicinal composition and its preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983977A (en) * 2015-06-17 2015-10-21 曾德锋 Externally-applied drug for treating traumatic injuries and preparing method thereof
CN111617172A (en) * 2020-05-22 2020-09-04 陈玉瑞 A topical Chinese medicinal composition and its preparation method

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