CN109329415A - A kind of baby formula milk powder - Google Patents
A kind of baby formula milk powder Download PDFInfo
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- CN109329415A CN109329415A CN201810974135.6A CN201810974135A CN109329415A CN 109329415 A CN109329415 A CN 109329415A CN 201810974135 A CN201810974135 A CN 201810974135A CN 109329415 A CN109329415 A CN 109329415A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
- A23C9/1206—Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
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Abstract
The present invention relates to a kind of baby formula milk powders, belong to technical field of processing dairy products.Baby formula milk powder of the invention includes following parts by weight of component: 30-42 parts of plant fat powder, 10-20 parts of milk protein powder, 31.98-48.45 parts of glucose solids syrup, 2-7 parts of sepg whey albumen powder, 3-6 parts of lactase, 0.1-1.5 parts of isomerizing lactose powder, 0.5-1.5 parts of compound probiotic freeze-dried powder, 0.05-0.07 parts of mineral substance premix, 0.15-0.2 parts of vitamin premix, 1.0-1.5 parts of nutrient, and the present invention further discloses the manufacture crafts that lactase nanoparticle is carried in the milk powder.Using milk powder not only adjustable infant's intestinal flora of technology disclosed by the invention production, infant's lactose intolerance bring is overcome to perplex, the ash content of milk powder can also be reduced, mitigated infant's kidney load, guarantee the healthy growth of infant.
Description
Technical field
The present invention relates to technical field of processing dairy products, and in particular to a kind of baby formula milk powder and preparation method thereof.
Background technique
Diarrhea is the common frdquently encountered disease of China infant.Due to infant's gastrointestinal tract and each systematic growth of whole body not at
It is ripe, immune function is not perfect, easily because virus, bacterium infection or dietary factor lead to diarrhea, damage mucous membrane of small intestine, be infantile period
A kind of acute gastrointestinal dysfunction, the syndrome based on diarrhea, vomiting.Wherein rotavirus enteritis accounts for about China children
The 40% of diarrhoeal diseases sum；Lactose intolerance incidence accounts for 46%-70%.Lactose intolerance (Lactose intolerance, LI)
Often refer to since mucous membrane of small intestine alactasia (Lactase deficiency, LD) causes caused by lactose digestion malabsorption
A series of clinical symptoms such as abdominal distension, diarrhea, abdominal pain.
Currently, for infant since rotavirus infection or lactose intolerance cause diarrhea to generally use Low lactose milk formula milk
Powder improves and is treated.Or Low lactose milk formula milk is usually all to replace cream using maltodextrin, corn in solids starch etc.
Sugar, although maltodextrin, corn in solids starch etc. can provide carbohydrate, its nutritive value is well below cream
Sugar；Lactase is either added into raw material milk, is hydrolyzed, and lactose content is reduced.But this technique is cumbersome, the technique ginseng needed
Number is more, and the time is longer, and the general percent hydrolysis of lactose is only between 30-40%.
In conclusion reducing the ash content in baby milk powder, overcoming infant's lactose intolerance is current baby milk powder
Urgent problem.
Summary of the invention
The purpose of the present invention is to solve the above problem, provides a kind of baby formula milk powder that the diarrhea phase uses and its system
Preparation Method eats the normal equilibrium that this milk powder is conducive to maintain infant's body, mitigates its kidney load, reduce kidney damage
Risk mitigates infantile diarrhea symptom caused by rotavirus or lactose intolerance, and provides the manufacturing method of the milk powder.
The present invention is implemented as follows:
Unless otherwise instructed, involved component number is parts by weight in this specification.
Baby formula milk powder of the invention includes following parts by weight of component: 30-42 parts of plant fat powder, milk protein powder
10-20 parts, 31.98-48.45 parts of glucose solids syrup, 2-7 parts of sepg whey albumen powder, 3-6 parts of lactase, isomerization cream
0.1-1.5 parts of Icing Sugar, 0.5-1.5 parts of compound probiotic freeze-dried powder, 0.05-0.07 parts of mineral substance premix, vitamin premix
0.15-0.2 parts, 1.0-1.5 parts of nutrient.
The present invention is added to the lactase and compound probiotic freeze-dried powder of appropriate amount in milk powder, the former can decompose cream
Sugar, compound probiotic mixing, which is added in milk powder, to act synergistically, and can effectively decompose to lactose, to alleviate lactose not
Resistance to disease.Furthermore it also added isomerizing lactose powder in milk powder of the invention, isomerizing lactose (4-O- β-galactopyranose-D- fruit
Sugar) it is by galactolipin and fructose with the disaccharide of β-(1-4) glucosides key connection, it cannot be generated naturally, be sent out by raw material of lactose
It gives birth to isomerization and generates.Isomerizing lactose can be decomposed in stomach and intestine by human digestive enzymes, large intestine can be reached, by Bifidobacterium
Equal intestinal beneficial bacteriums utilize, and have remarkable result to the proliferation of Bifidobacterium, to play a role in improving to intestinal flora, therefore right
Human body generates beneficial effect, the generation as reduced harmful substance in enteron aisle, prevention and mitigation constipation, booster immunization system etc..This
Outside, isomerizing lactose can be used in milk powder, biscuit, dispensed food for baby and beverage class as bifidus factor.Therefore, different
Source of the structure lactose as carbohydrate can replace lactose, and as unique disaccharide prebiotics, may also help in baby
Child forms the enteral environment of Bifidobacterium dominance to improve the resistance of itself.Not only by addition isomerizing lactose powder
Lactose intolerance can be alleviated, but also the growth of lactic bacteria useful in infant's enteron aisle can be promoted, promote the absorption of calcium.Most
Afterwards, the present invention reduces the content of ashes of milk powder, is more advantageous to the normal equilibrium for maintaining infant's body, mitigates kidney load, makes
Infant is obtained to be grown up healthy and sound.
Preferably, it is directed to the baby formula milk powder at 0-6 monthly age, 3-3.5 parts of lactase additive amount；6-12 months
The baby formula milk powder in age, 3.5-4.5 parts of lactase additive amount；The baby formula milk powder at 12-36 monthly age, lactase add
4.5-6.0 parts of dosage.So set, formula milk can be more preferable meet different phase infant demand.
Preferably, the enzyme activity of lactase is 100000ALU/g.
Preferably, the lactase of addition is to carry lactase nanoparticle.The small particle and high-specific surface area of nanoparticle, favorably
In the pharmaceutically-active contact area of increase, and lactase nanoparticle is carried with shell-core formula structure, small molecule can only be allowed logical
It crosses, and enzyme can not pass through, and can greatly promote the stability of lactase, to improve lactose decomposition efficiency.
Preferably, lactase nanoparticle preparation method the following steps are included:
(1) by the oil phase solvent of lactase soln injection polyacids cream, ultrasonic disperse operates to obtain colostrum；
(2) colostrum made from step 1 is added in the outer aqueous phase containing stabilizer, dispersion and emulsion obtains emulsion；
(3) emulsion made from step 2 is poured into the dilute acetic acid solution containing chitosan, stirring to solvent volatilization finishes；
(4) it is collected by centrifugation and carries lactase nanoparticle.
Preferably, preferred lactose content≤5% of milk protein；Preferred lactose content≤0.5% of sepg whey albumen powder.Compared with
The milk protein and sepg whey albumen powder of lower lactose level can avoid excessive while meeting baby to lactose demand
The intake of lactose causes even more serious lactose intolerance to react.
Preferably, it is HN019, BI-07, rhamnose cream bar that compound probiotic freeze-dried powder, which includes Bifidobacterium lactis strain number,
Bacteria strain LGG, HN001, one of L. reuteri strain DSM17938 or a variety of.These probiotics all have tune
The effect for saving intestinal flora, by cooperateing with the effect of lactase, further strengthening to compound probiotic freeze-dried powder is added in milk powder
The lactose intolerance of infant is preferably eliminated in decomposition to lactose, prevents infant's therefore diarrhea.
Preferably, the content of compound probiotic freeze-drying powder component is 1 ~ 1 × 109cfu/g。
Preferably, compound probiotic freeze-dried powder each component ratio is bifidobacterium lactis: Lactobacillus rhamnosus: Luo Yishi cream
Bacillus=2:1:1.The compound probiotic freeze-dried powder of the proportional amount allows three kinds of component probiotics preferably to cooperate with performance
Effect,
Preferably, also containing oligosaccharide in milk powder.Oligosaccharide is the prebiotic of promotion growth of probiotics with isomerizing lactose powder
Member, the dominant growth of probiotics can then make the illness rate of infant reduce, growth and development is more preferable.
Preferably, oligosaccharide includes: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose
One or more.
Preferably, isomerizing lactose powder: oligosaccharide: the weight ratio of compound probiotic freeze-dried powder is (0.3-5): (2-8):
(1-3).The sugar of the ratio and probiotics, preferably growth after compound probiotic can be made to enter in infants.
Except the puzzlements of diarrhea, more inorganic salts are often easily introduced in milk powder preparation, influence the health of infant,
And the ash content of current baby formula milk powder on the market is generally higher, so causes the kidney load of baby excessive, to baby children
Youngster's growth and development is unfavorable.Furthermore in a physiologically, the height of ash content is directly pressed with close relationship with infiltration, it and human body
Metabolic system is closely related with health, especially becomes more important for young infant.It eats to baby containing the milk powder more than inorganic salts, baby
In order to dilute inorganic salts as far as possible to drain, it is necessary to which many moisture are susceptible to suffer from high electrolysis when its consumption is greater than intake
Matter mass formed by blood stasis.Meanwhile intracellular solute concentration becomes larger, from body fluid absorption moisture, cell swelling causes edema, a large amount of in order to exclude
Inanimate matter, cause internal dehydration to cause dehydration disease, it is possible to will appear the relevant issues such as calculi in urinary system.
Therefore the problem high for milk powder ash content, inventive formulation advanced optimize, and sepg whey albumen powder salt rejection rate >=
90%, ash content≤5% of milk protein, ash content≤4% of isomerizing lactose powder.
Specific embodiment
Below by specific embodiment to further illustrate the technical scheme of the present invention.
Embodiment 1
Babies ' formula milk powder suitable for 12-36 monthly age includes: that 30 parts of plant fat powder, 20 parts of milk protein powder, glucose are solid
6 parts of lactase nanoparticle of 31.98 parts of body syrup, 7 parts of sepg whey albumen powder, lactase or load, 1.5 parts of isomerizing lactose powder,
1.5 parts of compound probiotic, 0.07 part of mineral substance premix, 0.2 part of vitamin premix, 1.5 parts of nutrient.
Compound probiotic freeze-dried powder is bifidobacterium lactis and Lactobacillus rhamnosus and lactobacillus reuteri, each component ratio are
2:1:1。
The sepg whey albumen powder lactose content is 0.5%, and the lactose content of the milk protein powder is 5 parts.
The ash content of milk protein is 5%, and the ash content of isomerizing lactose powder is 4%, the salt rejection rate of sepg whey albumen powder >=
90%。
Embodiment 2
The baby formula milk powder at 12-36 monthly age: 35 parts of plant fat powder, 15 parts of milk protein powder, glucose solids syrup
5 parts of lactase nanoparticle of 39 parts, 5 parts of sepg whey albumen powder, lactase or load, 0.8 part of isomerizing lactose powder, compound probiotic
1 part, 0.06 part of mineral substance premix, 0.17 part of vitamin premix, 1 part of nutrient, 5 parts of oligosaccharide.
The sepg whey albumen powder lactose content is 0.3%, and the lactose content of the milk protein powder is 3%.
The ash content of milk protein is 3%, and the ash content of isomerizing lactose powder is 3%, the salt rejection rate of sepg whey albumen powder >=
92%。
Compound probiotic freeze-dried powder is bifidobacterium lactis and Lactobacillus rhamnosus, and each component ratio is 2:1.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 3
The baby formula milk powder at 12-36 monthly age, comprising: 42 parts of plant fat powder, 10 parts of milk protein powder, glucose solids
4.6 parts of lactase nanoparticle of 48.45 parts of syrup, 2 parts of sepg whey albumen powder, lactase or load, 0.1 part of isomerizing lactose powder,
0.5 part of compound probiotic, 0.05 part of mineral substance premix, 0.15 part of vitamin premix, 1.25 parts of nutrient, 4 parts of oligosaccharide.
The sepg whey albumen powder lactose content is 0.2%, and the lactose content of the milk protein powder is 2%.
The ash content of milk protein is 2%, and the ash content of isomerizing lactose powder is 2%, the salt rejection rate of sepg whey albumen powder >=
95%。
Compound probiotic freeze-dried powder is bifidobacterium lactis or Lactobacillus rhamnosus or lactobacillus reuteri.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 4
The baby formula milk powder at 6-12 monthly age, comprising: 30 parts of plant fat powder, 20 parts of milk protein powder, glucose solids
4.5 parts of lactase nanoparticle of 33.73 parts of syrup, 7 parts of sepg whey albumen powder, lactase or load, 1.5 parts of isomerizing lactose powder,
1.5 parts of compound probiotic, 0.07 part of mineral substance premix, 0.2 part of vitamin premix, 1.5 parts of nutrient.
The sepg whey albumen powder lactose content is 0.5%, and the lactose content of the milk protein powder is 5 parts.
The ash content of milk protein is 5%, and the ash content of isomerizing lactose powder is 4%, the salt rejection rate of sepg whey albumen powder >=
90%。
Compound probiotic freeze-dried powder is bifidobacterium lactis and Lactobacillus rhamnosus and lactobacillus reuteri, each component ratio are
2:1:1。
Embodiment 5
The baby formula milk powder at 6-12 monthly age, comprising: 35 parts of plant fat powder, 15 parts of milk protein powder, glucose solids
35.47 parts of syrup, 5 parts of sepg whey albumen powder, lactase carry 4 parts of lactase nanoparticle, and 0.8 part of isomerizing lactose powder is answered
Close 1 part of probiotics, 0.06 part of mineral substance premix, 0.17 part of vitamin premix, 1 part of nutrient, 3.5 parts of oligosaccharide.
The sepg whey albumen powder lactose content is 0.3%, and the lactose content of the milk protein powder is 4%.
The ash content of milk protein is 3%, and the ash content of isomerizing lactose powder is 3%, the salt rejection rate of sepg whey albumen powder >=
92%。
Compound probiotic freeze-dried powder is bifidobacterium lactis and lactobacillus reuteri, and each component ratio is 2:1.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 6
The baby formula milk powder at 6-12 monthly age, comprising: 31 parts of plant fat powder, 10.5 parts of milk protein powder, glucose are solid
48.45 parts of body syrup, 2 parts of sepg whey albumen powder, lactase carry 3.5 parts of lactase nanoparticle, isomerizing lactose powder 0.1
Part, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, 0.15 part of vitamin premix, 1.25 parts of nutrient, oligosaccharide 3
Part.
The sepg whey albumen powder lactose content is 0.2%, and the lactose content of the milk protein powder is 2%.
The ash content of milk protein is 2%, and the ash content of isomerizing lactose powder is 2%, the salt rejection rate of sepg whey albumen powder >=
95%。
Compound probiotic freeze-dried powder is bifidobacterium lactis or Lactobacillus rhamnosus or lactobacillus reuteri.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 7
The baby formula milk powder at 0-6 monthly age, 30 parts of plant fat powder, 20 parts of milk protein powder, glucose solids syrup
34.83 parts, 7 parts of sepg whey albumen powder, lactase or carry 3.4 parts of lactase nanoparticle, it is 1.5 parts of isomerizing lactose powder, compound
1.5 parts of probiotics, 0.07 part of mineral substance premix, 0.2 part of vitamin premix, 1.5 parts of nutrient.
The sepg whey albumen powder lactose content is 0.5%, and the lactose content of the milk protein powder is 5%.
The ash content of milk protein is 5%, and the ash content of isomerizing lactose powder is 4%, the salt rejection rate of sepg whey albumen powder >=
90%。
Compound probiotic freeze-dried powder is bifidobacterium lactis and Lactobacillus rhamnosus and lactobacillus reuteri, each component ratio are
2:1:1。
Embodiment 8
The baby formula milk powder at 0-6 monthly age, comprising: 35 parts of plant fat powder, 15 parts of milk protein powder, glucose solids sugar
36.27 parts of slurry, 5 parts of sepg whey albumen powder, lactase carry 3.2 parts of lactase nanoparticle, and 0.8 part of isomerizing lactose powder is answered
Close 1 part of probiotics, 0.06 part of mineral substance premix, 0.17 part of vitamin premix, 1 part of nutrient, 2 parts of oligosaccharide.
The sepg whey albumen powder lactose content is 0.3%, and the lactose content of the milk protein powder is 4%.
The ash content of milk protein is 3%, and the ash content of isomerizing lactose powder is 3%, the salt rejection rate of sepg whey albumen powder >=
92%。
Compound probiotic freeze-dried powder is bifidobacterium lactis and lactobacillus reuteri, and each component ratio is 2:1.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 9
The baby formula milk powder at 0-6 monthly age, comprising: 31 parts of plant fat powder, 11 parts of milk protein powder, glucose solids sugar
48.45 parts of slurry, 2 parts of sepg whey albumen powder, lactase carry 3 parts of lactase nanoparticle, 0.1 part of isomerizing lactose powder, compound
0.5 part of probiotics, 0.05 part of mineral substance premix, 0.15 part of vitamin premix, 1.25 parts of nutrient, 1 part of oligosaccharide.
The sepg whey albumen powder lactose content is 0.2%, and the lactose content of the milk protein powder is 2%.
The ash content of milk protein is 2%, and the ash content of isomerizing lactose powder is 2%, the salt rejection rate of sepg whey albumen powder >=
95%。
Compound probiotic freeze-dried powder is bifidobacterium lactis or Lactobacillus rhamnosus or lactobacillus reuteri.
Oligosaccharide include: galactooligosaccharide, oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose one kind or
It is several.
Embodiment 10
A kind of preparation method of the milk powder, includes the following steps,
(1) auxiliary material is dry to water activity (AW)≤0.1；
(2) it is molten that mixing is made in component of the mixing in addition to compound probiotic freeze-dried powder, vitamin premix, nutrient, lactase
Liquid；
(3) homogeneous is carried out at 10-20MPa using high pressure homogenizer；
(4) it carries out spray drying and powdered original washing powder is made；
(4) compound probiotic freeze-dried powder, vitamin premix, nutrient, lactase is added to mix.
Embodiment 11
A kind of preparation method of the milk powder, comprising the following steps:
(1) vitamin premix, mineral substance premix, nutrient, lactase are mixed；
(2) mixing is added in remaining other raw materials, mixes.
Embodiment 12
Carry lactase nanoparticle preparation method the following steps are included:
1, lactase soln is injected in the oily phase of polyacids cream, and carries out scatter operation and obtains colostrum；
2, colostrum made from step 1 is added in the outer aqueous phase containing polyvinyl alcohol, carries out scatter operation and obtains emulsion；
3, emulsion made from step 2 is poured into polyvinyl alcohol water phase, stirring to solvent volatilization finishes；
4, it is collected by centrifugation and carries lactase nanoparticle
Embodiment 13
Animal comparative experiments
Male Wistar rat 350,3 monthly ages, were randomly divided into 7 groups, and each group 50, were given respectively by 200-250 grams of weight
The milk powder of following component is fed:
A group: ordinary powdered milk without lactase or carries lactase nanoparticle, compound probiotic freeze-dried powder, oligosaccharide, milk protein
Ash content with sepg whey albumen powder lactose content without limitation, milk protein and isomerizing lactose is without limitation, sepg whey albumen
The salt rejection rate of powder is not particularly limited.
B group: inventive formulation milk powder, a kind of baby formula milk powder comprise the following components in parts by weight: plant fat powder
31 parts, 10.5 parts of milk protein powder, 48.45 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, 3.5 parts of lactase, it is different
0.1 part of structure lactose powder, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, 0.15 part of vitamin premix, nutrient
1.25 part.
C group: inventive formulation milk powder, a kind of baby formula milk powder comprise the following components in parts by weight: plant fat powder
31 parts, 10.5 parts of milk protein powder, 48.45 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, load lactase nanoparticle
3.5 parts, 0.1 part of isomerizing lactose powder, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, vitamin premix 0.15
Part, 1.25 parts of nutrient.
D group: inventive formulation milk powder, a kind of baby formula milk powder comprise the following components in parts by weight: plant fat powder
31 parts, 10.5 parts of milk protein powder, 45.95 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, load lactase nanoparticle
3.5 parts, 0.1 part of isomerizing lactose powder, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, vitamin premix 0.15
Part, 1.25 parts of nutrient, 2.5 parts of oligofructose.
Wherein, ash content≤7% of milk protein；Ash content≤8% of isomerizing lactose powder；The salt rejection rate of sepg whey albumen powder
≥70%。
E group: inventive formulation milk powder, a kind of baby formula milk powder comprise the following components in parts by weight: plant fat powder
31 parts, 10.5 parts of milk protein powder, 45.95 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, load lactase nanoparticle
3.5 parts, 0.1 part of isomerizing lactose powder, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, vitamin premix 0.15
Part, 1.25 parts of nutrient, 2.5 parts of oligofructose.
Wherein: preferred lactose content≤5% of milk protein；Preferred lactose content≤0.5% of sepg whey albumen powder.
F group: inventive formulation milk powder, a kind of baby formula milk powder comprise the following components in parts by weight: plant fat powder
31 parts, 10.5 parts of milk protein powder, 45.95 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, load lactase nanoparticle
3.5 parts, 0.1 part of isomerizing lactose powder, 0.5 part of compound probiotic, 0.05 part of mineral substance premix, vitamin premix 0.15
Part, 1.25 parts of nutrient, 2.5 parts of oligofructose.
Wherein, ash content≤5% of milk protein；Ash content≤4% of isomerizing lactose powder；The salt rejection rate of sepg whey albumen powder
≥90%。
G group: a kind of baby formula milk powder comprises the following components in parts by weight: 31 parts of plant fat powder, milk protein powder
10.5 parts, 48.45 parts of glucose solids syrup, 2 parts of sepg whey albumen powder, 3.5 parts of lactase, 0.1 part of isomerizing lactose powder,
0.05 part of mineral substance premix, 0.15 part of vitamin premix, 1.25 parts of nutrient.
Rat adaptable fed 1 week under identical environment, subsequent 4 weeks each group rats are fed by above-mentioned feeding patterns
It raises.Period observes the stool situation of rat, and 1d with metabolic cage collects the urine of each group rat for 24 hours (1% Sodium azide is anti-before experiment terminates
Corruption, 4 DEG C of preservations), urine volume is surveyed, urine galactose detection is carried out；Chloraldurate (volume fraction) after experiment after execution with 10%
1ml intraperitoneal injection, takes a blood sample after anesthesia from cavity of resorption, surveys serum creatinine, blood uric acid；The double kidneys of vertical profile each group rat, microscopic observation nephridial tissue
Size, form and pathological change.
Experimental result is as follows:
According to experiment, each group urine volume no significant difference for 24 hours, D group, the serum creatinine of F group and other each groups, blood uric acid difference
There is significant.And by dissection discovery, A, B, C, E, F, G group kidney increase without obvious shape, but D group finds nephridial tissue
There is oedema phenomenon；Other group of nephridial tissue structure is clear, the boundary of skin medullary substance is clear, and oedema and crystalline material are had no in tissue.It says
Bright low ash divides formula milk compared with high ash divides formula milk, and high ash content milk powder can cause the lesion of nephridial tissue, then causes kidney
The lesions such as the calculus of tissue, the constitution that low ash divides formula milk to be more suitable for infant.
From experimental result as can be seen that A group urine galactose is measured as the positive, C, D, E, F, G group urine galactose are measured as yin
Property, illustrate that milk formula of the invention has good relaxation effect for lactose intolerance.
Claims (10)
1. a kind of baby formula milk powder, comprises the following components in parts by weight: 30-42 parts of plant fat powder, milk protein powder 10-
20 parts, 31.98-48.45 parts of glucose solids syrup, 2-7 parts of sepg whey albumen powder, 3-6 parts of lactase, isomerizing lactose powder
0.1-1.5 parts, 0.5-1.5 parts of compound probiotic freeze-dried powder, 0.05-0.07 parts of mineral substance premix, vitamin premix 0.15-
0.2 part, 1.0-1.5 parts of nutrient.
2. a kind of baby formula milk powder according to claim 1, which is characterized in that the lactase is to carry lactase
Nanoparticle.
3. a kind of baby formula milk powder according to claim 1 or 2, which is characterized in that be directed to the baby at 0-6 monthly age
Baby formulas milk powder, 3-3.5 parts of lactase additive amount；The baby formula milk powder at 6-12 monthly age, lactase additive amount 3.5-
4.5 part；The baby formula milk powder at 12-36 monthly age, 4.5-6.0 parts of lactase additive amount.
4. a kind of baby formula milk powder according to claim 1 or 2, which is characterized in that further include 1-5 parts of oligosaccharide.
5. a kind of baby formula milk powder according to claim 4, which is characterized in that oligosaccharide include: galactooligosaccharide,
The one or more of oligofructose, xylo-oligosaccharide, isomalto-oligosaccharide and stachyose.
6. a kind of baby formula milk powder according to claim 1 or 2, which is characterized in that the milk protein is preferred
Lactose content≤5%；Preferred lactose content≤0.5% of sepg whey albumen powder.
7. a kind of baby formula milk powder according to claim 1 or 2, which is characterized in that compound probiotic freeze-dried powder packet
Include: Bifidobacterium lactis strain number is HN019, BI-07, Lactobacillus rhamnosus strain LGG, HN001, L. reuteri strain
One of number DSM17938 or a variety of.
8. a kind of baby formula milk powder according to claim 7, it is characterised in that each group in compound probiotic freeze-dried powder
Dividing ratio is bifidobacterium lactis: Lactobacillus rhamnosus: lactobacillus reuteri=2:1:1.
9. a kind of baby formula milk powder according to claim 1 or 2, which is characterized in that the ash of the milk protein
Divide≤5%；Ash content≤4% of isomerizing lactose powder；Salt rejection rate >=90% of sepg whey albumen powder.
10. a kind of baby formula milk powder as claimed in claim 2, the preparation method therein for carrying lactase nanoparticle include with
Lower step:
(1) by the oil phase solvent of lactase soln injection polyacids cream, ultrasonic disperse operates to obtain colostrum；
(2) colostrum made from step 1 is added in the outer aqueous phase containing stabilizer, dispersion and emulsion obtains emulsion；
(3) emulsion made from step 2 is poured into the dilute acetic acid solution containing chitosan, stirring to solvent volatilization finishes；
(4) it is collected by centrifugation and carries lactase nanoparticle.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810974135.6A CN109329415A (en) | 2018-08-24 | 2018-08-24 | A kind of baby formula milk powder |
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| WO2021093880A1 (en) * | 2019-11-15 | 2021-05-20 | 内蒙古伊利实业集团股份有限公司 | Synergistic combination of butyric-acid-producing prebiotics and probiotics |
| CN113973926A (en) * | 2021-10-18 | 2022-01-28 | 临夏燎原乳业产业研究院有限公司 | Infant series yak milk formula milk powder and preparation method thereof |
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