CN109200113A - Chinese medicine composition and preparation method thereof for weight-reducing - Google Patents

Abstract

The Chinese medicine composition and preparation method thereof that the invention discloses a kind of for weight-reducing, the composition are made of the raw material components of following parts by weight: 15-22 parts of Radix Astragali, 10-20 parts of Ilex Latifolia Thunb, 8-15 parts of ginseng, 11-20 parts of Poria cocos, 9-19 parts of gynostemma pentaphylla, 13-22 parts of cassia seed, 15-25 parts of Chinese torreyanut, 8-18 parts of perilla leaf, 10-22 parts of Prunella vulgaris, 11-21 parts of dark plum, 7-11 parts of Radix Glycyrrhizae.Up to 97%, quick, pharmacological property mitigates drug effective percentage of the present invention, and toxic side effect is small；Full side's legislation is careful, compatibility is precise and appropriate, is consolidated with strengthening the spleen and replenishing qi, and Li Shui helps digestion temporary solution, and simultaneous with heat-clearing, stagnation resolvation, giving consideration to both the incidental and fundamental, tonification and purgation in combination；User can not only know from experience road of the Chinese medicine eliminating evil without hurting positive traditional methods to keep in good health, be really achieved weight reducing without hurting healthy tendency, can also achieve the purpose that lower blood-fat and reduce weight and be in a cheerful frame of mind；Lower blood-fat and reduce weight not wound body, weight does not rebound after drug withdrawal, and prevents to feel depressed during weight-reducing.

Description

Chinese medicine composition and preparation method thereof for weight-reducing

Technical field

The invention belongs to Chinese medicine and health food technical fields, are related to a kind of for the Chinese medicine composition of weight-reducing and its preparation side Method.

Background technique

Conventional weight-reducing thinking has three: sharp water defaecation helps digestion and drops turbid, appetite-suppressing.It is thermophilic since overweight people is mostly because of honey stomach Caused by eating delicious food, and extra fat belongs to damp evil scope for Chinese medicine, and dampness being heavy and turbid is sticky, is easy to be detained in vivo, and Two just tonneaus are influenced, so conventional weight-reducing is just conceived at two, one is control intake, and two is reinforce excluding, then promoting diuresis to clear away damp pathogen Lotus leaf, semen coicis, rhizoma alismatis, the hawthorn to help digestion, malt, Divine Comedy, aloe, rheum officinale, the folium sennae of defaecation become diet products Trump medication.But this thinking is entirely to see that mark loses this, and firstly, overweight people's chronic dietary does not save, Energy intaking mistake It is more, cause taste to bear, with the passing of time impairing the spleen and stomach, and the medication of the appetite-suppressing often more impairment of the spleen, so this control intake Mode loses more than gain.Meanwhile spleen injury, transporting is unfavorable, causes water-wet, having indigestion to be stagnated, sharp water defaecation seems just at only Method.No matter the aloe of the hawthorn or defaecation that help digestion, rheum officinale are all straight male however, the lotus leaf of existing diet products benefit water Scholar, walk cruelly simply and ignore help, so, though the effect in a period of time can be shown off, lead to more hurting for taste, often rebound after drug withdrawal Rapidly, such vicious circle is singly that also difficulty of losing weight obtains good effect just not saying body is difficult to persistently.Based on the above reasons, the present invention is logical Research Obese Mechanism is crossed, has developed a kind of Chinese medicine composition for weight-reducing and preparation method thereof to solve these problems.

Summary of the invention

The Chinese medicine composition and preparation method thereof that the object of the present invention is to provide a kind of for weight-reducing, to solve above-mentioned background The problem of being previously mentioned in technology.

The technical scheme adopted by the invention is that a kind of Chinese medicine composition for weight-reducing, by the raw material of following parts by weight Component is made: 15-22 parts of Radix Astragali, 10-20 parts of Ilex Latifolia Thunb, 8-15 parts of ginseng, 11-20 parts of Poria cocos, 9-19 parts of gynostemma pentaphylla, cassia seed 13-22 parts, 15-25 parts of Chinese torreyanut, 8-18 parts of perilla leaf, 10-22 parts of Prunella vulgaris, 11-21 parts of dark plum, 7-11 parts of Radix Glycyrrhizae.

Further, a kind of Chinese medicine composition for weight-reducing, is made of the raw material components of following parts by weight: Radix Astragali 17- 21 parts, 14-18 parts of Ilex Latifolia Thunb, 11-15 parts of ginseng, 13-17 parts of Poria cocos, 12-16 parts of gynostemma pentaphylla, 16-20 parts of cassia seed, Chinese torreyanut 18-22 parts, 11-15 parts of perilla leaf, 15-19 parts of Prunella vulgaris, 15-19 parts of dark plum, 7-11 parts of Radix Glycyrrhizae.

Further, a kind of Chinese medicine composition for weight-reducing, is made of the raw material components of following parts by weight: Radix Astragali 19 Part, 16 parts of Ilex Latifolia Thunb, 13 parts of ginseng, 15 parts of Poria cocos, 14 parts of gynostemma pentaphylla, 18 parts of cassia seed, 20 parts of Chinese torreyanut, 13 parts of perilla leaf, summer 17 parts of withered grass, 17 parts of dark plum, 9 parts of Radix Glycyrrhizae.

A kind of preparation method of the Chinese medicine composition for weight-reducing, prepares as follows:

(1) Radix Astragali, Ilex Latifolia Thunb, ginseng, Poria cocos, gynostemma pentaphylla, cassia seed, Chinese torreyanut, perilla leaf, summer are weighed respectively by weight Withered grass, dark plum, licorice medicinal materials add the slightly boiled decoction of water three times, for the first time plus are equivalent to 10-13 times of above-mentioned raw materials gross mass and measure water, It decocts 80-90min, second plus is equivalent to 8-10 times of above-mentioned raw materials gross mass and measures water, decoct 50-60min, third time plus suitable Water is measured in 6-8 times of above-mentioned raw materials gross mass, decocts 25-45min, is merged decocting liquid three times, is cooled filtering, be concentrated under reduced pressure into 1-2g/ ML, it is spare；

(2) concentrate obtained in step (1) is added into auxiliary material, the finished dosage forms of clinical needs is made.

Capsule, tablet, pill, granule or oral solution can be made in the Chinese medicine composition for weight-reducing.

The effect of forming each raw material of the invention activity is as follows:

The present invention is using Radix Astragali, Ilex Latifolia Thunb, ginseng as monarch drug in a prescription.

Radix Astragali: for perennial herb.Chinese medicine thinks " the spleen being the foundation of acquired constitution ".Taste send representative figure Li Gao to think Radix Astragali " beneficial vigour and mend three coke ", it is referred to as " all medicines of tonifying Qi most " that Radix Astragali is embroidered in the yellow palace of the Qing Dynasty.Warm-natured sweet in flavor, return lung, the spleen channel are main to use In invigorating qi, consolidating exterior, promoting urination and detoxification, apocenosis, expelling pus and promoting granulation.For deficiency of vital energy and acking in strength, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, just Metrorrhagia leakage, exterior deficiency spontaneous perspiration, deficiency of vital energy and edema, ulcer is difficult to burst, burst for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic rephrilis protinuria, Diabetes.Radix Astragali is sweet in flavor, and gas tepor, gas is thin and taste is dense, and can rise can drop, and the yang aspect of yang is nontoxic.Special tonifying Qi.Start with lunar, sufficient Lunar, hand lacks the warp of yin.Its function is a lot of, and its only effect person, is enriching blood especially.

Ilex Latifolia Thunb: have effects that clearing heat and cooling blood, nourishing liver are kidney nourishing.

Ginseng: this product is the dry root of Araliaceae ginseng.Sweet in flavor, slight bitter, it is mild-natured；Returns spleen lung, the heart channel of Hang-Shaoyin；Big complement Gas, veins takes off admittedly reinforce the spleen to benefit the lung, and promote the production of body fluid, and calm the nerves.

The present invention is using Poria cocos, gynostemma pentaphylla, cassia seed, Chinese torreyanut as ministerial drug.

Poria cocos: Poria cocos " long term usage, peace soul are reposed, not hungry macrobiosis " is said in Shennong's Herbal.Poria cocos has antitoxic heart-soothing and sedative, loses The effect of malicious anticancer.Medicinal peace, dampness removing is without hurting healthy tendency.The maintenance good merchantable brand that can be used as spring and summer wet season is taken in right amount, it can Control difficult urination, edema swelling, sip and cough, the diseases such as inverse, vomiting during early pregnancy, diarrhea, spermatorrhea, stranguria with turbid discharge, palpitation with fear, amnesia of vomitting.Contained Poria cocos Acid has the function of strengthen immunity, antitumor and calm, hypoglycemic etc., and can relax gastrointestinal smooth muscle, gastric acid inhibitory point It secretes, prevents necrosis of liver cells, antibacterial and other effects.

Gynostemma pentaphylla: for cucurbitaceous plant also known as seven leaf gallbladders, bitter is cold in nature, has clearing heat and detoxicating, eliminating the phlegm, reducing blood lipid, drop blood Pressure, hypoglycemic, calm, hypnosis, anti-anxiety, antiulcer, it is antifatigue, extend and cell survival and improve a poor appetite, build up resistance, Unobstructed stool, antiasthmatic-antitussive, the hemorrhoid that disappear, the treatment chronic diseases marked by deficiency of vital energy, inhibit gall stone to be formed, prevent and treat glucocorticoid side effect, is anti-ageing weight-reducing It waits for a long time multiple efficacies；There are reduction total cholesterol, triglycerides and increasing high density lipoprotein effect, adjustable body fat generation It thanks, enhances human immunity.

Cassia seed: it is bitter, sweet, it is cool in nature, enter liver kidney channel, has the function of clearing liver and improving vision, sharp water defaecation.

Chinese torreyanut: Chinese torreyanut is warm-natured sweet in flavor, enters large intestine channel, relax bowel and defecation.

The present invention is using perilla leaf, Prunella vulgaris, dark plum as adjutant.

Perilla leaf: slightly warm in nature acrid flavour, nontoxic, returns spleen, lung two pass through.Cure cold chill, fever with aversion to cold, coughs, asthma, chest and abdomen Turgor, threatened abortion, headache nasal obstruction.And it can solving toxin of fish and crab.

Prunella vulgaris: for the wounded in the battle fruit ear of Labiatae herbaceos perennial Prunella vulgaris.Also known as iron color grass, wooden club grass etc.. With clearing away the liver-fire, the effect of Disperse hepatic depression.It is its bitter, pungent, it is cold in nature.Main product is in Soviet Union, Zhejiang, Anhui, Henan and other places.Zoopery confirms decoction Have decompression, diuresis, shrink uterus, enhancing enterocinesia the effects of, clinic be usually used in headache caused by controlling hypertension, irascibility, dizziness, The illnesss such as red eye, swell pain, photophobia shed tears, goiter, scrofula.

Dark plum: its taste is extremely sour, and sour person holds back, and shrinks loose adipose tissue.Sour person changes.Change fat be protein, Sugar supplies body energy.

The present invention is to make medicine with Radix Glycyrrhizae.

Radix Glycyrrhizae: it is sweet in flavor, it is mild-natured；It invigorates the spleen and benefits qi, is clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；For taste Weakness, shortness of breath and palpitation, coughing with a lot of sputum, wrist abdomen, four limbs contraction, too fat to move sore, alleviates drug toxicity, is strong fatigue and weakness.

The beneficial effects of the present invention are: a variety of medicinal materials are used cooperatively by the present invention, weight-reducing can be treated by having developed one kind Chinese medicine composition, drug effective percentage is up to 97%, and quick, pharmacological property mitigates, and toxic side effect is small, no dependence；Full side's legislation Careful, medication is fastidious, compatibility is precise and appropriate, is consolidated with strengthening the spleen and replenishing qi, and Li Shui helps digestion temporary solution, and simultaneous with heat-clearing, stagnation resolvation, giving consideration to both the incidental and fundamental is attacked Mend simultaneous apply；The present invention has fully demonstrated the theory of Traditional Chinese Medicine strengthening vital QI to eliminate pathogenic factors, and user can not only know from experience Chinese medicine eliminating evil without hurting just Traditional methods to keep in good health road, be really achieved weight reducing without hurting healthy tendency, can also achieve the purpose that lower blood-fat and reduce weight and be in a cheerful frame of mind；Lipid-loweringing subtracts Fertile not wound body, weight does not rebound after drug withdrawal, and prevents to feel depressed during weight-reducing.

Specific embodiment

In order to enable those skilled in the art to more fully understand, technical solution of the present invention is practiced, below with reference to specific The invention will be further described for embodiment, but illustrated embodiment is not as a limitation of the invention.

Embodiment 1

(1), Radix Astragali 19g, Ilex Latifolia Thunb 16g, ginseng 13g, Poria cocos 15g, gynostemma pentaphylla 14g, cassia seed 18g, Chinese torreya are weighed respectively Sub- 20g, perilla leaf 13g, Prunella vulgaris 17g, dark plum 17g, Radix Glycyrrhizae 9g add the slightly boiled decoction of water three times, for the first time plus are equivalent to above-mentioned 12 times of amount water of total mass of raw material decoct 85min, for the second time plus are equivalent to 9 times of amount water of above-mentioned raw materials gross mass, decoct 55min, the Three times plus 7 times of amount water of above-mentioned raw materials gross mass are equivalent to, decoct 30min, collecting decoction cools filtering, is concentrated under reduced pressure into 1-2g/ ML, it is spare；

(2), concentrate obtained in step (1) is added into auxiliary material, mouth is made using modern general traditional chinese medicine preparation technology Take liquid.

Embodiment 2

(1), Radix Astragali 17g, Ilex Latifolia Thunb 14g, ginseng 11g, Poria cocos 13g, gynostemma pentaphylla 12g, cassia seed 16g, Chinese torreya are weighed respectively Sub- 18g, perilla leaf 11g, Prunella vulgaris 15g, dark plum 15g, Radix Glycyrrhizae 7g add the slightly boiled decoction of water three times, for the first time plus are equivalent to above-mentioned 10 times of amount water of total mass of raw material decoct 80min, for the second time plus are equivalent to 8 times of amount water of above-mentioned raw materials gross mass, decoct 50min, the Three times plus 6 times of amount water of above-mentioned raw materials gross mass are equivalent to, decoct 25min, collecting decoction cools filtering, is concentrated under reduced pressure into 1-2g/ ML, it is spare；

(2), concentrate obtained in step (1) is added into auxiliary material, ball is made using modern general traditional chinese medicine preparation technology Agent.

Embodiment 3

(1), Radix Astragali 21g, Ilex Latifolia Thunb 18g, ginseng 15g, Poria cocos 17g, gynostemma pentaphylla 16g, cassia seed 20g, Chinese torreya are weighed respectively Sub- 22g, perilla leaf 15g, Prunella vulgaris 19g, dark plum 19g, Radix Glycyrrhizae 11g add the slightly boiled decoction of water three times, for the first time plus are equivalent to above-mentioned 13 times of amount water of total mass of raw material decoct 90min, for the second time plus are equivalent to 10 times of amount water of above-mentioned raw materials gross mass, decoct 60min, Third time, which adds, is equivalent to 8 times of amount water of above-mentioned raw materials gross mass, decocts 45min, collecting decoction cools filtering, is concentrated under reduced pressure into 1- 2g/mL, it is spare；

(2), concentrate obtained in step (1) is added into auxiliary material, is made using modern general traditional chinese medicine preparation technology Granula.

Embodiment 4

(1), Radix Astragali 22g, Ilex Latifolia Thunb 10g, ginseng 15g, Poria cocos 20g, gynostemma pentaphylla 19g, cassia seed 13g, Chinese torreya are weighed respectively Sub- 25g, perilla leaf 8g, Prunella vulgaris 22g, dark plum 11g, Radix Glycyrrhizae 7g add the slightly boiled decoction of water three times, for the first time plus are equivalent to above-mentioned original Expect 11 times of amount water of gross mass, decoct 85min, for the second time plus is equivalent to 9 times of amount water of above-mentioned raw materials gross mass, decocts 50min, third It is secondary plus be equivalent to 6 times of amount water of above-mentioned raw materials gross mass, decoct 30min, merging decocting liquid three times cools filtering, is concentrated under reduced pressure into 1- 2g/mL, it is spare；

(2), concentrate obtained in step (1) is added into auxiliary material, piece is made using modern general traditional chinese medicine preparation technology Agent.

Embodiment 5

(1) Radix Astragali 15g, Ilex Latifolia Thunb 20g, ginseng 8g, Poria cocos 11g, gynostemma pentaphylla 9g, cassia seed 22g, Chinese torreyanut are weighed respectively 15g, perilla leaf 18g, Prunella vulgaris 10g, dark plum 21g, Radix Glycyrrhizae 11g add the slightly boiled decoction of water three times, for the first time plus are equivalent to above-mentioned original Expect 13 times of amount water of gross mass, decoct 90min, for the second time plus is equivalent to 10 times of amount water of above-mentioned raw materials gross mass, decocts 50min, the Three times plus 7 times of amount water of above-mentioned raw materials gross mass are equivalent to, decoct 45min, merge decocting liquid three times, cool filtering, be concentrated under reduced pressure into 1-2g/mL, it is spare；

(2) concentrate obtained in step (2) is added into auxiliary material, capsule is made using modern general traditional chinese medicine preparation technology Agent.

Clinical test results:

Embodiment 1-3 is the significant Chinese medicine composition of therapeutic effect, wherein the Chinese medicine obtained by embodiment 1 for weight-reducing The clinical application of composition is as follows: 200 patients of the ages between 18-50 years old are screened in 3 hospitals, wherein women 100, Male 100, the most heavy 98.5kg of weight, be most gently 70kg；Abdominal circumference is up to 120cm, minimum 88cm；Fat history longest 15 Year, it is most 5 years short.

The crowd is observed continuously in the last week of experiment, records symptom and changes of weight, is randomly divided into two groups, in fact Group and control group are tested, experimental group uses the made traditional Chinese medicine oral liquid of the embodiment of the present invention 1, and control group uses common treatment in the market The drug of weight-reducing.

Curative effect situation criterion: effective: two courses for the treatment of (course for the treatment of is one month) weight loss 5kg or more is taken, Abdominal circumference reduces 10cm or more, and blood lipid restores normal, and has significant difference before treatment；It is effective: to take two courses for the treatment of (course for the treatment of It is one month) 3~5kg of weight loss, abdominal circumference reduces 5cm or more, and rate and blood-lipid decreased but be still higher than before normal value, with treatment has significant Sex differernce；It is invalid: to take two courses for the treatment of (course for the treatment of is one month) weight loss less than 3kg, abdominal circumference is reduced less than 5cm, blood Rouge is higher than there was no significant difference before normal value, with treatment.

Instructions of taking: taking the oral solution that the embodiment of the present invention 1 is prepared during treatment, a 10mL is sooner or later each daily It takes once, continuously takes two courses for the treatment of, the results are shown in Table 1.

Table 1 takes the verifying of 1 products obtained therefrom therapeutic effect of embodiment

	Experimental group	Control group
			Number of cases	100	100
Male's number of cases	50	50
			Women number of cases	50	50
Effective number of cases	28	10
			Effective number of cases	69	81
Invalid number of cases	3	9
			It is efficient	97%	91%

Therapeutic effect: from table 1, it is apparent that taking the Chinese medicine composition obtained by the embodiment of the present invention 1 for weight-reducing Experimental group effective and effective totally 97 (97%), it is invalid 3 (3%).And the effective percentage of control group only reaches 91%, takes The experimental group of Chinese medicine composition of the gained of the invention for weight-reducing is substantially better than the control group for taking other drugs.

In addition, patient is after taking two courses for the treatment of, it is discontinued two months, carries out rebound rate detection, take 1 institute of the embodiment of the present invention The effective patient and effective patient for the Chinese medicine composition that must be used to lose weight be discontinued after without rebound, and take and commonly control in the market The drug rebound rate for treating weight-reducing is up to 48%.

Disclosed above is only specific embodiments of the present invention, and still, the embodiment of the present invention is not limited to this, Ren Heben What the technical staff in field can think variation should all fall into protection scope of the present invention.

Claims (5)

1. a kind of Chinese medicine composition for weight-reducing, which is characterized in that the Chinese medicine composition by following parts by weight raw material group Divide and be made:

15-22 parts of Radix Astragali, 10-20 parts of Ilex Latifolia Thunb, 8-15 parts of ginseng, 11-20 parts of Poria cocos, 9-19 parts of gynostemma pentaphylla, cassia seed 13-22 Part, 15-25 parts of Chinese torreyanut, 8-18 parts of perilla leaf, 10-22 parts of Prunella vulgaris, 11-21 parts of dark plum, 7-11 parts of Radix Glycyrrhizae.

2. the Chinese medicine composition as described in claim 1 for weight-reducing, which is characterized in that the Chinese medicine composition is by following heavy The raw material components of amount part are made:

17-21 parts of Radix Astragali, 14-18 parts of Ilex Latifolia Thunb, 11-15 parts of ginseng, 13-17 parts of Poria cocos, 12-16 parts of gynostemma pentaphylla, cassia seed 16- 20 parts, 18-22 parts of Chinese torreyanut, 11-15 parts of perilla leaf, 15-19 parts of Prunella vulgaris, 15-19 parts of dark plum, 7-11 parts of Radix Glycyrrhizae.

3. the Chinese medicine composition as claimed in claim 2 for weight-reducing, which is characterized in that the Chinese medicine composition is by following heavy The raw material components of amount part are made:

19 parts of Radix Astragali, 16 parts of Ilex Latifolia Thunb, 13 parts of ginseng, 15 parts of Poria cocos, 14 parts of gynostemma pentaphylla, 18 parts of cassia seed, 20 parts of Chinese torreyanut, purple perilla 13 parts of leaf, 17 parts of Prunella vulgaris, 17 parts of dark plum, 9 parts of Radix Glycyrrhizae.

4. the preparation method of the Chinese medicine composition a method according to any one of claims 1-3 for weight-reducing, which is characterized in that by as follows Step preparation:

(1) it is withered that Radix Astragali, Ilex Latifolia Thunb, ginseng, Poria cocos, gynostemma pentaphylla, cassia seed, Chinese torreyanut, perilla leaf, summer are weighed respectively by weight Grass, dark plum, licorice medicinal materials add the slightly boiled decoction of water three times, for the first time plus are equivalent to 10-13 times of above-mentioned raw materials gross mass and measure water, decoct 80-90min is boiled, second plus 8-10 times of above-mentioned raw materials gross mass is equivalent to and measures water, decocts 50-60min, third time plus is equivalent to 6-8 times of above-mentioned raw materials gross mass measures water, decocts 25-45min, merges decocting liquid three times, cools filtering, be concentrated under reduced pressure into 1-2g/mL, It is spare；

(2) concentrate obtained in step (1) is added into auxiliary material, the finished dosage forms of clinical needs is made.

5. the Chinese medicine composition for weight-reducing as described in claim 1-3, which is characterized in that the Chinese medicine composition can be made At capsule, tablet, pill, granule or oral solution.