CN109170254A - A kind of feed and preparation method thereof preventing edema disease of piglets - Google Patents

A kind of feed and preparation method thereof preventing edema disease of piglets Download PDF

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Publication number
CN109170254A
CN109170254A CN201810913331.2A CN201810913331A CN109170254A CN 109170254 A CN109170254 A CN 109170254A CN 201810913331 A CN201810913331 A CN 201810913331A CN 109170254 A CN109170254 A CN 109170254A
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parts
feed
piglets
edema disease
chinese medicine
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不公告发明人
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Foshan Sanshui Charles Agricultural Technology Research Institute (general Partner)
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
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    • A23K20/116—Heterocyclic compounds
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract

The invention belongs to feed processing technologies, disclose a kind of feed and preparation method thereof for preventing edema disease of piglets, it is influenced each other by Indian Flagellaria glycosides displayed and each middle the effective elements of the medicine, synergistic effect, improve immunity of organisms and disease resistance, colony balance is adjusted by saccharomycete, improve intestinal health, promote to absorb and digest, promote the healthy fast-growth of piglet, and the nutriment of comprehensive and abundant is supplemented for body, enhancing development, the resisting stress of piglet is improved from many aspects, immunocompetence and disease resistance, in the generation for fundamentally effectively preventing edema disease of piglets, to have certain preventive and therapeutic action to hydropsy for baby pigs.

Description

A kind of feed and preparation method thereof preventing edema disease of piglets
Technical field
The present invention relates to feed processing technologies, and in particular to a kind of feed for preventing edema disease of piglets and its preparation side Method.
Background technique
Hydropsy for baby pigs is a kind of enterotoxemia of piglet after weaning as caused by enteropathogenic E. Coli, is mainly shown as Sudden onset, locomotor ataxia are fainted from fear, locally or systemically paralysis and eyelid portion oedema, and the disease course of disease is short, and cure rate is low, are caused Dead rate is high, and disease incidence 5-30%, the death rate is up to 90% or more, has infectiousness, acute, height lethal and sporadic Feature, the disease have become pig breeding industry and endanger more serious one of disease.At present to the disease not yet reliable therapeutic scheme, because This prevents early, makes a definite diagnosis in time, and takes and accordingly effectively prevent measure, to pig breeding industry sound development important in inhibiting.China Patent " a kind of feed for preventing bowel oedema disease " (patent publication No.: CN106721325A) disclose one kind have no toxic side effect, price The feed of immunity of organisms cheap, simple for production and that illness pig can be improved and disease resistance；A kind of patent " prevention and treatment edema disease of piglets The feed and preparation method thereof of disease " (patent publication No.: CN106937711A) discloses one kind to promote piglet to feed, it improves The immunity and disease resistance of piglet reduce the feed of oedema incidence, but above-mentioned patent only enhances piglet by Chinese medicine and exempts from Epidemic disease power resists the generation of oedema, the growth and breeding without fundamentally inhibiting harmful bacteria, and therefore, research and development are a fundamentally It solves the problems, such as bowel oedema disease, enhances pigling immunity, the problem of feed for improving disease resistance is current urgent need to resolve.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of feed and preparation method thereof for preventing edema disease of piglets, pass through Indian Flagellaria glycosides displayed and a middle the effective elements of the medicine influence each other, synergistic effect, improve immunity of organisms, and utilize saccharomycete tune Intestinal health is saved, promotes to digest and assimilate, and nutriment abundant, enhancing development can also be supplemented for body.
The present invention can be achieved through the following technical solutions:
A kind of feed preventing edema disease of piglets, it is composed of the following components: 40-45 parts of barley, 10-20 parts of rape cake, wheat bran 10-15 parts, 5-10 parts of dregs of beans, 3-5 parts of fish meal, 0.5-1 parts of shellfish powder, 0.5-1 parts of calcium bicarbonate, 1-1.5 parts of calcium monohydrogen phosphate, palpus leaf 3-5 parts of guttiferone glucoside, 0.05-0.1 parts of trace mineral supplement, 0.05-0.1 parts of threonine, relies ammonia at 3-5 parts of Chinese medicine additive 0.1-0.2 parts sour, 0.2-0.4 parts of histidine, 0.05-0.1 parts of vitamin E, 0.2-0.4 parts of salt, 1-1.5 parts of complex enzyme, ferment Female bacterium 0.05-0.1 parts.
Preferably, a kind of feed preventing edema disease of piglets is composed of the following components: 41-44 parts of barley, rape cake 12- 18 parts, 11-14 parts of wheat bran, 6-9 parts of dregs of beans, 3.5-4.5 parts of fish meal, 0.6-0.9 parts of shellfish powder, 0.6-0.9 parts of calcium bicarbonate, phosphoric acid 1.1-1.4 parts of hydrogen calcium, 3.5-4.5 parts of Indian Flagellaria glycosides displayed, 3.5-4.5 parts of Chinese medicine additive, trace mineral supplement 0.06- 0.09 part, 0.06-0.09 parts of threonine, 0.12-0.18 parts of lysine, 0.25-0.35 parts of histidine, vitamin E 0.06- 0.09 part, 0.25-0.35 parts of salt, 1.1-1.4 parts of complex enzyme, 0.06-0.09 parts of saccharomycete.
Preferably, a kind of feed preventing edema disease of piglets is composed of the following components: 42 parts of barley, 15 parts of rape cake, 13 parts of wheat bran, 7 parts of dregs of beans, 4 parts of fish meal, 0.8 part of shellfish powder, 0.7 part of calcium bicarbonate, 1.3 parts of calcium monohydrogen phosphate, Indian Flagellaria glycosides displayed 4 Part, 4 parts of Chinese medicine additive, 0.08 part of trace mineral supplement, 0.07 part of threonine, 0.15 part of lysine, 0.3 part of histidine, 0.08 part of vitamin E, 0.3 part of salt, 1.2 parts of complex enzyme, saccharomycete 0.08.
Preferably, the Indian Flagellaria glycosides displayed the preparation method comprises the following steps:
A. it takes Indian Flagellaria to be ground into the particle that granularity is 0.5-1.5cm, is that 50% ethanol solution is added in 1:8 by solid-liquid ratio In, after impregnating 3-5h at 70 DEG C, refluxing extraction 2h is extracted twice, and filtering, combined extract is recovered under reduced pressure ethyl alcohol, obtains dense Contracting liquid；
B. it takes concentrate that the flocculant of concentrate 2% is added, stirs evenly, staticly settle, centrifuging and taking supernatant is used The sodium hydrate aqueous solution of 0.5mol/L adjusts supernatant pH to 9, generates flocculent deposit, and centrifugal filtration takes filtrate to use 0.5mol/ The aqueous hydrochloric acid solution of L adjust filtrate pH to；
C. it takes D101 resin and polyamide to mix dress column by 1:1, the extracting solution of above-mentioned purifying is pressed into 3g/100ml tree The upper column quantity upper prop of rouge, with the distillation water elution of 4 times of column volumes, then with 20% ethanol elution of 2 times of volumes, then with 70% second Alcohol desorption takes stripping liquid concentrated, dry, obtains glycosides displayed.
Preferably, the Chinese medicine additive includes following components composition: 10-12 parts windproof, 8-12 parts of the root of Dahurain angelica, dried orange peel 15- 20 parts, 12-15 parts of Radix Angelicae Sinensis, 15-20 parts of Poria cocos, 15-20 parts of Radix Paeoniae Alba, 20-25 parts of Rhizoma Atractylodis Macrocephalae, 8-10 parts of monkshood, 10-15 parts of Radix Glycyrrhizae.
Preferably, the Chinese medicine additive includes following components composition: windproof 11 parts, 10 parts of the root of Dahurain angelica, 18 parts of dried orange peel, Radix Angelicae Sinensis 13 parts, 17 parts of Poria cocos, 18 parts of Radix Paeoniae Alba, 22 parts of Rhizoma Atractylodis Macrocephalae, 9 parts of monkshood, 13 parts of Radix Glycyrrhizae.
Preferably, the Chinese medicine additive the preparation method comprises the following steps: taking the radix saposhnikoviae, root of Dahurain angelica, dried orange peel, Radix Angelicae Sinensis, Poria cocos, Radix Paeoniae Alba, white The mixing of the Chinese medicines such as art, monkshood and Radix Glycyrrhizae is placed in 60 DEG C of drying boxes dry 48h, crushes, and is that distillation is added in 1:10 by solid-liquid ratio Water, heating and refluxing extraction 2 times, each 1h, filtering merges filtrate twice, takes filtrate rotary evaporation to be concentrated, until filter liquor concentration is 1g/L, then it is spray-dried, it crushed 60 meshes to get Chinese medicine additive.
Preferably, the trace mineral supplement includes following components composition: 0.001-0.003 parts of ferrous sulfate, sulfuric acid 0.001-0.002 parts of copper, 0.001-0.003 parts of zinc sulfate, 0.02-0.04 parts of calcium carbonate, 0.001-0.002 parts of sodium selenite.
Preferably, the trace mineral supplement includes following components composition: 0.002 part of ferrous sulfate, copper sulphate 0.0015 part, 0.002 part of zinc sulfate, 0.03 part of calcium carbonate, 0.0015 part of sodium selenite.
A kind of preparation method for the feed preventing edema disease of piglets, comprising the following steps:
(1) by barley, rape cake, wheat bran, dregs of beans, fish meal, calcium bicarbonate, calcium monohydrogen phosphate, Bei Fen, threonine, lysine, The mixing such as histidine, salt, vitamin E, Indian Flagellaria glycosides displayed, trace mineral supplement, Chinese medicine additive, stirs evenly；
(2) it takes step (1) mixture that distilled water is added for 1:2 by solid-liquid ratio sufficiently to moisturize, stirs evenly, be placed in 121 Sterilize 20min at DEG C；
(3) mixture after sterilizing is cooled to room temperature, complex enzyme is added, the constant temperature 72h at 50 DEG C is daily to shake bottle 2 times；
(4) saccharomycete is placed at 25 DEG C after activating 2h, is accessed in fermentation material, ferment 96h in 30 DEG C of incubators；
(5) feed after fermentation is placed in tray, hot wind air-dries 12-24h to get present invention prevention piglet at 50 DEG C The feed of oedema.
Each main composition mechanism of action of the present invention is as follows:
Indian Flagellaria is Flagellariaceae Indian Flagellaria platymiscium, warm-natured, flat, acrid flavour, swollen with alleviating water retention, convergence wound function Effect, main active are glycosides displayed, such as Kaempferol -3- glycoside, ferulic acid, p-Coumaric Acid, sinapic acid, have and change Mercy Cerebrovascular disorders, spasmolysis, antiallergy and the effects of adjust metabolic, antiviral, antibacterial anti-inflammatory, and have no toxic side effect, There is different degrees of bacteriostasis to Pseudomonas aeruginosa, Escherichia coli, typhoid bacillus, shigella dysenteriae, staphylococcus aureus etc.；
Radix saposhnikoviae is Umbelliferae herbaceos perennial, and rhizome is medicinal, plays the role of inducing diaphoresis sweating, dispelling wind and eliminating dampness, also has There is enhancing immune function, there is centainly antibacterial to various bacteria such as shigella dysenteriae, staphylococcus aureus and Pseudomonas aeruginosa etc. The pharmacological actions such as antibacterial action；The root of Dahurain angelica is umbelliferae, has expelling cold, eliminating, sensible analgesic, eliminating dampness stops band, detumescence and apocenosis etc. Effect also has antibacterial action, has different degrees of inhibiting effect to Escherichia coli, shigella dysenteriae, typhoid bacillus etc.；When Return and enriches blood and the effect of blood, regulating menstruation, hemostasis, ease constipation laxation, the immune function of body, anti-inflammatory work with higher can be enhanced Property.
Dried orange peel has the function of regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, and has apparent antibacterial ability, contained active constituent orange Skin glycosides can also reinforce gastric emptying, promote gastrointestinal disturbances ability, also have stronger insecticidal activity；Poria cocos has clearing damp and promoting diuresis, is good for The effect of spleen calming heart, common-use words treat edema and little urine, phlegm retention anti-dazzle nervous, spleen eating less etc.；Radix Paeoniae Alba cold nature, bitter acid, contains The effective components such as Paeoniflorin, Chinese herbaceous peony lactones glycosides, paeonol, have nourishing blood and liver, it is slow in analgesic, the row stasis of blood, cool blood, reduce swelling and hold back yin The effect of receiving sweat.
Rhizoma Atractylodis Macrocephalae has effects that invigorate the spleen and benefit qi, eliminate dampness and have diuretic effect, strengthening exterior and reducing sweat, and there is Rhizoma Atractylodis Macrocephalae obvious and lasting diuresis to make With, and bowel movement can be promoted, and immune function can be enhanced；Monkshood pharmacological property is pungent, sweet, big heat, have recuperating depleted yang, mends fire supporing yang, The effect of eliminating cold to stop pain, contained active ingredients Biogenic alkali have apparent anti-inflammatory and analgesic effect and make to the adjusting of immune system With；Radix Glycyrrhizae is the drying root and rhizome of leguminous plant Glycyrrhiza Uralensis, contains plurality of active ingredients, including triterpenes, flavones Class, polysaccharide etc. have clearing heat and detoxicating, qualcomm meridian, sharp vim and vigour, cough-relieving apophlegmatic, tonifying spleen stomach function regulating, coordinating the drug actions of a prescription and other effects.
The present invention have it is following the utility model has the advantages that
(1) present invention is purified the effective component glycosides displayed in Indian Flagellaria using resin, can effectively improve content of total flavonol glycosides, Increase antimicrobial and anti-inflammation efficacy, has certain inhibiting effect to harmful bacteria in intestine of young pigs, to adjust flora in intestine of young pigs Balance, fundamentally effectively prevents the generation of edema disease of piglets；
(2) present invention is added to Chinese medicines such as radix saposhnikoviae, the root of Dahurain angelica, dried orange peel, Radix Angelicae Sinensis, Poria cocos, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, monkshood and Radix Glycyrrhizaes The Chinese medicine additive being mixed is influenced each other by each middle the effective elements of the medicine, and synergistic effect inhibits harmful in intestine of young pigs Bacterium promotes enteron aisle to digest and assimilate, improves the immunocompetence and disease resistance of piglet, promote the growth and development of piglet；
(3) present invention also added the microelements such as sodium selenite and vitamin E and vitamin, can provide for piglet abundant Nutriment, to white muscle disease, piglet liver malnutrition, hydropsy for baby pigs etc. have certain preventive and therapeutic action, and benefit With saccharomycete and complex enzyme, intestine of young pigs colony balance is adjusted, the activity of digestive ferment is improved, it is strong so as to improve the enteron aisle of piglet Health, and promote to digest and assimilate, improve the growth performance of piglet；
(4) feed of the invention is rich in nutriment and bioactivity, comprehensively can provide battalion needed for growth for piglet It supports, promotes the growth and development of piglet, additionally it is possible to adjust the intestinal flora balance of piglet, improve intestinal health, promote to absorb and disappear Change, promotes the healthy fast-growth of piglet；Feed of the invention can also improve the resisting stress of piglet, immunocompetence and disease-resistant Ability has certain preventive and therapeutic action to hydropsy for baby pigs, to improve the quality and edible safety of pork.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below Specific embodiment is closed, the present invention is further explained.
A kind of embodiment 1-5 formula of feed for preventing edema disease of piglets of the present invention, as shown in table 1:
Table 1
Above-mentioned Indian Flagellaria glycosides displayed the preparation method comprises the following steps:
A. it takes Indian Flagellaria to be ground into the particle that granularity is 0.5-1.5cm, is that 50% ethanol solution is added in 1:8 by solid-liquid ratio In, after impregnating 3-5h at 70 DEG C, refluxing extraction 2h is extracted twice, and filtering, combined extract is recovered under reduced pressure ethyl alcohol, obtains dense Contracting liquid；
B. it takes concentrate that the flocculant of concentrate 2% is added, stirs evenly, staticly settle, centrifuging and taking supernatant is used The sodium hydrate aqueous solution of 0.5mol/L adjusts supernatant pH to 9, generates flocculent deposit, and centrifugal filtration takes filtrate to use 0.5mol/ The aqueous hydrochloric acid solution of L adjust filtrate pH to；
C. it takes D101 resin and polyamide to mix dress column by 1:1, the extracting solution of above-mentioned purifying is pressed into 3g/100ml tree The upper column quantity upper prop of rouge, with the distillation water elution of 4 times of column volumes, then with 20% ethanol elution of 2 times of volumes, then with 70% second Alcohol desorption takes stripping liquid concentrated, dry, obtains glycosides displayed.
Above-mentioned Chinese medicine additive includes following components composition: windproof 11 parts, 10 parts of the root of Dahurain angelica, 18 parts of dried orange peel, 13 parts of Radix Angelicae Sinensis, Fu 17 parts of Siberian cocklebur, 18 parts of Radix Paeoniae Alba, 22 parts of Rhizoma Atractylodis Macrocephalae, 9 parts of monkshood, 13 parts of Radix Glycyrrhizae.
Above-mentioned Chinese medicine additive the preparation method comprises the following steps: taking radix saposhnikoviae, the root of Dahurain angelica, dried orange peel, Radix Angelicae Sinensis, Poria cocos, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, monkshood It is mixed with Chinese medicines such as Radix Glycyrrhizaes, is placed in 60 DEG C of drying boxes dry 48h, crushes, be that distilled water is added in 1:10 by solid-liquid ratio, heat back Stream extracts 2 times, each 1h, and filtering merges filtrate twice, and filtrate rotary evaporation is taken to be concentrated, until filter liquor concentration is 1g/L, then through spraying Mist dry, pulverize 60 meshes to get Chinese medicine additive.
Above-mentioned trace mineral supplement includes following components composition: 0.002 part of ferrous sulfate, 0.0015 part of copper sulphate, sulphur 0.002 part of sour zinc, 0.03 part of calcium carbonate, 0.0015 part of sodium selenite.
A kind of preparation method of above-mentioned feed for preventing edema disease of piglets, comprising the following steps:
(1) by barley, rape cake, wheat bran, dregs of beans, fish meal, calcium bicarbonate, calcium monohydrogen phosphate, Bei Fen, threonine, lysine, The mixing such as histidine, salt, vitamin E, Indian Flagellaria glycosides displayed, trace mineral supplement, Chinese medicine additive, stirs evenly；
(2) it takes step (1) mixture that distilled water is added for 1:2 by solid-liquid ratio sufficiently to moisturize, stirs evenly, be placed in 121 Sterilize 20min at DEG C；
(3) mixture after sterilizing is cooled to room temperature, complex enzyme is added, the constant temperature 72h at 50 DEG C is daily to shake bottle 2 times；
(4) saccharomycete is placed at 25 DEG C after activating 2h, is accessed in fermentation material, ferment 96h in 30 DEG C of incubators；
(5) feed after fermentation is placed in tray, hot wind air-dries 12-24h to get present invention prevention piglet at 50 DEG C The feed of oedema.
Embodiment 6
Above-mentioned Chinese medicine additive includes following components composition: windproof 10 parts, 8 parts of the root of Dahurain angelica, 15 parts of dried orange peel, 12 parts of Radix Angelicae Sinensis, Fu 15 parts of Siberian cocklebur, 15 parts of Radix Paeoniae Alba, 20 parts of Rhizoma Atractylodis Macrocephalae, 8 parts of monkshood, 10 parts of Radix Glycyrrhizae.
Above-mentioned trace mineral supplement includes following components composition: 0.001 part of ferrous sulfate, 0.001 part of copper sulphate, sulfuric acid 0.001 part of zinc, 0.02 part of calcium carbonate, 0.001 part of sodium selenite.
Embodiment 7
Above-mentioned Chinese medicine additive includes following components composition: windproof 12 parts, 12 parts of the root of Dahurain angelica, 20 parts of dried orange peel, 15 parts of Radix Angelicae Sinensis, Fu 20 parts of Siberian cocklebur, 20 parts of Radix Paeoniae Alba, 25 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of monkshood, 15 parts of Radix Glycyrrhizae.
Above-mentioned trace mineral supplement includes following components composition: 0.003 part of ferrous sulfate, 0.002 part of copper sulphate, sulfuric acid 0.003 part of zinc, 0.04 part of calcium carbonate, 0.002 part of sodium selenite.
Comparative example 1
The difference from embodiment 1 is that without addition Chinese medicine additive in composition of raw materials.
Comparative example 2
The difference from embodiment 1 is that without addition Indian Flagellaria glycosides displayed in composition of raw materials.
Comparative example 3
The difference from embodiment 1 is that there is no saccharomycete, complex enzyme, trace mineral supplement and dimension to give birth in composition of raw materials Plain E.
Efficacy validation
Piglet 100 are taken, is randomly divided into 10 groups, every group 10, wherein 7 groups of feedings for giving the preparation of embodiment 1-7 group respectively Material, remaining 3 groups are given feed prepared by comparative example 1-3 group, after continuous 4 weeks, one month, take the Escherichia coli bacterium for having increased bacterium 18h Liquid makees lethal hit, and raising 1 week is further continued for after infection, records animal dead number and cures number, calculates the death rate and total effective Rate, and experiment front and back pig weight is recorded, gaining effect is calculated, result is as shown in table 2, table 3:
The comparison of 2 each group therapeutic effect of table
Group Number of cases Death toll/head Death rate % Cure number/head Significant figure/head Total effective rate %
Embodiment 1 10 1 10 4 5 90
Embodiment 2 10 1 10 5 4 90
Embodiment 3 10 1 10 5 4 90
Embodiment 4 10 1 10 6 3 90
Embodiment 5 10 1 10 5 4 90
Embodiment 6 10 1 10 5 4 90
Embodiment 7 10 1 10 4 5 90
Comparative example 1 10 4 40 3 3 60
Comparative example 2 10 5 50 3 2 50
Comparative example 3 10 6 60 2 2 40
As shown in Table 2, after coli-infection, the death rate of embodiment 1-7 group is only 10%, with comparative example 1-3 group Compared to significant difference, and the cure rate of embodiment 1-7 group and it is efficient organized than comparative example 1-3 high, illustrate this hair The feed of the prevention edema disease of piglets of bright preparation has good therapeutic effect to edema disease of piglets.
3 each group piglet of table experiment front and back weight compares
Group Test precursor mass/kg Weight/kg after experiment Rate of body weight gain %
Embodiment 1 9.02 11.68 88.67
Embodiment 2 9.28 11.98 90.00
Embodiment 3 8.99 11.88 96.33
Embodiment 4 8.98 11.95 99.00
Embodiment 5 9.10 11.96 95.33
Embodiment 6 8.96 11.68 90.67
Embodiment 7 8.91 11.54 87.67
Comparative example 1 9.08 8.13 31.67
Comparative example 2 9.15 8.43 24.00
Comparative example 3 9.21 8.59 20.67
As shown in Table 3, after the test, for weight than increasing before testing, rate of body weight gain is up to 99% to embodiment 1-7 group, Compared with comparative example 1-3 group, the difference with conspicuousness illustrates that the feed of prevention edema disease of piglets prepared by the present invention can be improved The feed intake of piglet promotes to digest and assimilate, enhances pigling immunity, to promote the healthy growth of piglet.
In conclusion the Feed Energy of prevention edema disease of piglets prepared by the present invention provides the nutrients of comprehensive and abundant for piglet Matter promotes piglet development, enhances pigling immunity and disease resistance, moreover it is possible to adjust intestine of young pigs colony balance, inhibit to have Evil bacterium growth and breeding, fundamentally reduces the incidence of edema disease of piglets, to effectively prevent edema disease of piglets, and to edema disease of piglets With certain therapeutic effect.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously Limitations on the scope of the patent of the present invention therefore cannot be interpreted as.It should be pointed out that for those of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention Protect range.

Claims (10)

1. a kind of feed for preventing edema disease of piglets, which is characterized in that composed of the following components: 40-45 parts of barley, rape cake 10- 20 parts, 10-15 parts of wheat bran, 5-10 parts of dregs of beans, 3-5 parts of fish meal, 0.5-1 parts of shellfish powder, 0.5-1 parts of calcium bicarbonate, calcium monohydrogen phosphate 1- 1.5 parts, 3-5 parts of Indian Flagellaria glycosides displayed, 3-5 parts of Chinese medicine additive, 0.05-0.1 parts of trace mineral supplement, threonine 0.05- 0.1 part, 0.1-0.2 parts of lysine, 0.2-0.4 parts of histidine, 0.05-0.1 parts of vitamin E, 0.2-0.4 parts of salt, complex enzyme 1-1.5 parts, 0.05-0.1 parts of saccharomycete.
2. a kind of feed for preventing edema disease of piglets according to claim 1, which is characterized in that composed of the following components: big 41-44 parts of wheat, 12-18 parts of rape cake, 11-14 parts of wheat bran, 6-9 parts of dregs of beans, 3.5-4.5 parts of fish meal, 0.6-0.9 parts of shellfish powder, carbon 0.6-0.9 parts of sour hydrogen calcium, 1.1-1.4 parts of calcium monohydrogen phosphate, 3.5-4.5 parts of Indian Flagellaria glycosides displayed, 3.5-4.5 parts of Chinese medicine additive, 0.06-0.09 parts of trace mineral supplement, 0.06-0.09 parts of threonine, 0.12-0.18 parts of lysine, histidine 0.25-0.35 Part, 0.06-0.09 parts of vitamin E, 0.25-0.35 parts of salt, 1.1-1.4 parts of complex enzyme, 0.06-0.09 parts of saccharomycete.
3. a kind of feed for preventing edema disease of piglets according to claim 1 or 2, which is characterized in that composed of the following components: 42 parts of barley, 15 parts of rape cake, 13 parts of wheat bran, 7 parts of dregs of beans, 4 parts of fish meal, 0.8 part of shellfish powder, 0.7 part of calcium bicarbonate, calcium monohydrogen phosphate 1.3 parts, 4 parts of Indian Flagellaria glycosides displayed, 4 parts of Chinese medicine additive, 0.08 part of trace mineral supplement, 0.07 part of threonine, lysine 0.15 part, 0.3 part of histidine, 0.08 part of vitamin E, 0.3 part of salt, 1.2 parts of complex enzyme, saccharomycete 0.08.
4. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the Indian Flagellaria Glycosides displayed the preparation method comprises the following steps:
A. it takes Indian Flagellaria to be ground into the particle that granularity is 0.5-1.5cm, is that 1:8 is added in 50% ethanol solution by solid-liquid ratio, After impregnating 3-5h at 70 DEG C, refluxing extraction 2h is extracted twice, and filtering, combined extract is recovered under reduced pressure ethyl alcohol, obtains concentrate；
B. it takes concentrate that the flocculant of concentrate 2% is added, stirs evenly, staticly settle, centrifuging and taking supernatant uses 0.5mol/L Sodium hydrate aqueous solution adjust supernatant pH to 9, generate flocculent deposit, centrifugal filtration takes filtrate with the hydrochloric acid of 0.5mol/L Aqueous solution adjust filtrate pH to；
C. D101 resin and polyamide is taken to mix dress column by 1:1, by the extracting solution of above-mentioned purifying by 3g/100ml resin Upper column quantity upper prop, with the distillation water elution of 4 times of column volumes, then with 20% ethanol elution of 2 times of volumes, then with 70% ethyl alcohol solution It inhales, takes stripping liquid concentrated, dry, obtain glycosides displayed.
5. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the Chinese medicine adds Adding agent includes following components composition: 10-12 parts windproof, 8-12 parts of the root of Dahurain angelica, 15-20 parts of dried orange peel, 12-15 parts of Radix Angelicae Sinensis, Poria cocos 15-20 Part, 15-20 parts of Radix Paeoniae Alba, 20-25 parts of Rhizoma Atractylodis Macrocephalae, 8-10 parts of monkshood, 10-15 parts of Radix Glycyrrhizae.
6. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the Chinese medicine adds Adding agent includes following components composition: 11 parts of radix saposhnikoviae, 10 parts of the root of Dahurain angelica, 18 parts of dried orange peel, 13 parts of Radix Angelicae Sinensis, 17 parts of Poria cocos, 18 parts of Radix Paeoniae Alba, white 22 parts of art, 9 parts of monkshood, 13 parts of Radix Glycyrrhizae.
7. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the Chinese medicine adds Add agent the preparation method comprises the following steps: takes the Chinese medicines such as radix saposhnikoviae, the root of Dahurain angelica, dried orange peel, Radix Angelicae Sinensis, Poria cocos, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, monkshood and Radix Glycyrrhizae to mix, and sets The dry 48h in 60 DEG C of drying boxes, crushes, and is 1:10 addition distilled water by solid-liquid ratio, and heating and refluxing extraction 2 times, each 1h, mistake Filter merges filtrate twice, and filtrate rotary evaporation is taken to be concentrated, until filter liquor concentration is 1g/L, then spray-dried, crushed 60 mesh Sieve is to get Chinese medicine additive.
8. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the micro member Plain additive includes following components composition: 0.001-0.003 parts of ferrous sulfate, 0.001-0.002 parts of copper sulphate, zinc sulfate 0.001-0.003 parts, 0.02-0.04 parts of calcium carbonate, 0.001-0.002 parts of sodium selenite.
9. a kind of feed for preventing edema disease of piglets according to claim 1-3, which is characterized in that the micro member Plain additive includes following components composition: 0.002 part of ferrous sulfate, 0.0015 part of copper sulphate, 0.002 part of zinc sulfate, calcium carbonate 0.03 part, 0.0015 part of sodium selenite.
10. preparation such as a kind of described in any item methods for the feed for preventing edema disease of piglets of claim 1-9, which is characterized in that The following steps are included:
(1) by barley, rape cake, wheat bran, dregs of beans, fish meal, calcium bicarbonate, calcium monohydrogen phosphate, Bei Fen, threonine, lysine, group ammonia The mixing such as acid, salt, vitamin E, Indian Flagellaria glycosides displayed, trace mineral supplement, Chinese medicine additive, stirs evenly；
(2) it takes step (1) mixture that distilled water is added for 1:2 by solid-liquid ratio sufficiently to moisturize, stirs evenly, be placed at 121 DEG C Sterilize 20min；
(3) mixture after sterilizing is cooled to room temperature, complex enzyme is added, the constant temperature 72h at 50 DEG C is daily to shake bottle 2 times；
(4) saccharomycete is placed at 25 DEG C after activating 2h, is accessed in fermentation material, ferment 96h in 30 DEG C of incubators；
(5) feed after fermentation is placed in tray, hot wind air-dries 12-24h to get present invention prevention edema disease of piglets at 50 DEG C Feed.
CN201810913331.2A 2018-08-10 2018-08-10 A kind of feed and preparation method thereof preventing edema disease of piglets Pending CN109170254A (en)

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Application publication date: 20190111