CN104351563A - Functional feed used for preventing pig malignant edema and preparation method of functional feed - Google Patents

Functional feed used for preventing pig malignant edema and preparation method of functional feed Download PDF

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CN104351563A
CN104351563A CN201410694573.9A CN201410694573A CN104351563A CN 104351563 A CN104351563 A CN 104351563A CN 201410694573 A CN201410694573 A CN 201410694573A CN 104351563 A CN104351563 A CN 104351563A
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weight portion
feed
chinese medicine
functional feed
medicine additive
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郝常宝
黄河
李鑫
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Shandong New Hope Liuhe Group Co Ltd
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Shandong New Hope Liuhe Group Co Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
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    • Y02P60/87Re-use of by-products of food processing for fodder production

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Abstract

The invention discloses a functional feed used for preventing pig malignant edema and a preparation method of the functional feed. The feed is prepared from the following raw materials: corn, wheat bran, bone meal, soybean cakes, vinasse, table salt, shell meal, white radishes, dried grass, bean dregs, wheat straw, silkworm chrysalis, fish meal, rapeseed cakes, peanut cakes, calcium hydrogen phosphate, taros, an antioxidant, carrots, microelements and lysine. The preparation method comprises the following steps: preparing a traditional Chinese medicine additive, crushing part of raw materials, mixing and granulating, and drying the grain feed. The functional feed used for preventing the pig malignant edema has the beneficial effects that the feed contains the traditional Chinese medicine additive which has the effects of removing heat to cool blood and inducing diuresis to alleviate edema, and has the advantages of strengthening body resistance and eliminating evil, having good curative effect and no medical residue and having low cost and price and the like; and the traditional Chinese medicine additive and other feed raw materials are matched and acted so that the pig malignant edema can be prevented and the nutritional requirements of pigs can be met.

Description

A kind of for preventing functional feed of pig malignant edema and preparation method thereof
Technical field
The present invention relates to beasts feed, particularly a kind of for preventing functional feed of pig malignant edema and preparation method thereof.
Background technology
Malignant edema (Malignat edema) is the acute infectious disease of the microbial multiple domestic animal of multiple shuttle being master by clostridium septicum.Sick feature is that sharply gas inflammatory edema locally occurs wound, and with heating and whole body toxaemia.There is generation these sick countries in the world, and Chinese Pigs also has Sporadic cases.
Germ: the cause of disease of this disease is clostridium septicum in fusobacterium (Clostridium), clostridieum welchii, Nuo Weishi clostridium and clostridium histolyticum etc., but in malignant edema case, have 60% separable to clostridium septicum, next is clostridieum welchii, and Nuo Weishi clostridium and clostridium histolyticum only account for 5%.1. clostridium septicum is strict anaerobes, is the Gram-positive escherichia coli of the blunt circle in two ends, can not forms pod membrane, can form brood cell, and brood cell is positioned at thalline central authorities or near-end, and brood cell is oval or circle, is greater than thalline shape as shuttle shape; There are all flagellums, can move.In the medium thalline singly or in short chain shape, if the thalline on the peritonaeum or liver surface of dead animal, often form long filament without joint microbend or articulate long-chain shape, this feature has diagnostic value.It is 37 ~ 40 DEG C that this bacterium cultivates optimum temperature, well-grown on the culture medium being added with blood, serum or carbohydrate.In β haemolysis on blood agar; In anaerobism liver bouillon, well-grown, evenly muddy, last top is limpid, forms canescence flocculent deposit, sinks.This bacterium energy glucose fermentation, maltose, single toffee, fructose, salicin, lactose, produce sour aerogenesis; Azymic sucrose, dulcitol and sweet mellow wine; Reduction nitrate, solidifies slowly to litmus milk, does not produce indole and hydrogen sulfide, MR and VP negative.This bacterium can produce multiple exotoxin, mainly α, β, γ, δ 4 kinds of exotoxins, and alpha toxin is lecithinase, has necrosis, lethal and haemocylolysis, is the primary toxins of this bacterium; β toxin is deoxyribonuclease, has and kills leucocyte effect; γ and δ toxin has the hemolysin activity of hyaluronidase and not oxytolerant respectively, and they can make vasopermeability strengthen, and make inflammatory seep, and constantly organize diffusion towards periphery, makes musculature downright bad, and infection is spread along the manadesma face of muscle.This bacterium extensively exists at nature, has a large amount of bacterium, can pollute feeding environment and soil in the enteron aisle of animal and ight soil.This bacterium gemma resistance is to external world very strong, and general sterilization liquid needs just can kill for a long time; In sterilization liquid, 10% ~ 20% Eusol, 3% ~ 5% sulfuric acid, carbolic acid mixture, 3% ~ 5% NaOH, can kill this bacterium thalline at short notice.2. clostridieum welchii (also known as C.perfringens) is the Gram-positive escherichia coli of the blunt circle in two ends, singly or become way double-line, seldom there is short chain; Atrichia, can not move; Oval brood cell, is positioned at thalline central authorities or near-end, thalline is expanded; Most bacterial strain can form pod membrane.This bacterium requires not tight to anaerobic condition, ordinary culture medium can grow, if add blood, glucose, grows better; On sheep blood agar culture medium, can grow circle, neat in edge, grey to grey yellow, smooth surface, translucent bacterium colony, periphery of bacterial colonies has zone of hemolysis.In anaerobism liver bouillon, grow vigorous, cultivate 5 ~ 6h for 37 DEG C, namely see that culture medium is muddy, produce a large amount of gas.This bacterium energy glucose fermentation, maltose, lactose, sucrose, fructose and galactolipin, produce sour aerogenesis; Azymic salicin, dulcitol, sweet mellow wine and rhamnose; Liquefy gelatin, indole produces negative, and " the violent fermentation " of milk culturemedium, produces a large amount of gas and make clot disruption become porous spongy, is washed into several sections or be ejected outside pipe time serious, is the outstanding biochemical characteristic of this bacterium.
Epidemiology: the pathogen of this disease extensively exists and gives nature, more in livestock intestinal tract sweetening of the soil, becomes the infection sources.Ill domestic animal can not immediate contagion healthy animal, but can pollute external environment.During the edematous site generation ulceration of ill domestic animal, discharge a large amount of pathogen with edematous fluid or slough, contaminated environment.This disease transmission approach mainly due to wound, castration, bite, dock, operation, the sterilization such as practise midwifery be tight, pollute bacterial spore and infect, causing morbidity, especially with deep wounds, and there is slough, causing anoxic, more susceptible disease.
Clinical symptoms: face and examine visible two kinds of sick types.A kind of is wound infection, and show as local diffuse inflammatory oedema, the initial stage is solid, has hotness, pain, after become not hot, palpation local is more soft, and firmly visible oedema depression, during for twisting, has obvious crepitus; Risings of sick pig performance body temperature, lassitude, appetite are given up the constitutional symptom such as exhausted, severe one death in 1 ~ 2 day.Another kind is gastric pattern, and epidemic disease of also expressing one's gratification type, is mainly infected by stomach lining, makes stomach lining swelling, thickens, and is formed so-called " rubber stomach ".Sometimes germ also can enter blood flow, is transferred to certain muscle, and limping of arching appears gas inflammatory edema and in local, and constitutional symptom is obvious; This case is often in acute process, how dead at 1 ~ 2 day.
Pathological change: cut open the visible site of pathological change diffusivity oedema of inspection, cut affected part as seen between subcutaneous and muscle connective tissue have dirty yellow or bronzing liquid-soaked, its taste acid is smelly, and containing bubble; Muscle is in white, and seemingly boiled the same, soft being easy to is torn, and what have is crineous.Organa parenchymatosum's sex change, the heart, liver, kidney cloudy swelling; Enlargement of lymph nodes, particularly infects the acute enlargement of lymph node of local, and tangent plane is congested, hemorrhage.Blood clotting is bad, and there is volume hydrops in pericardium and abdominal cavity.As being stomach infections, then see thickened stomach wall, matter as rubber-like, therefore has the title of " rubber stomach ".Stomach lining flush, swelling, be filled with pale red and mixed alveolate liquid under mucous membrane and between muscle layer.Hepatic tissue is mostly also containing bubble.
Antidiastole: face the feature of examining according to this disease, pathological anatomical change and be combined with wound when occurring, can suspect for this disease, but needs to carry out laboratory examination and just can make a definite diagnosis.Bacterium smear, dyeing, microscopy get pathology edematous fluid and tissue, and particularly liver tunicle does contact or smear, with Gram's stain dyeing, and microexamination.In the staining section of liver, can see the Gram-positive escherichia coli of microbend long filament shape arrangement, this is significant in diagnosis.Bacteria distribution is cultivated and is got local edema liquid or hepatic tissue pathological material of disease, is inoculated in anaerobism liver bouillon culture medium, and cultivate 24h for 37 DEG C, liver bouillon is evenly muddy, and produces gas, has precipitation; On glucose blood agar, in faint β haemolysis; Divide pure bacterium can do biochemical test further.Animal inoculation pvaccination test is got pathological material of disease and is made 1:10 emulsion suspension liquid, the animals used as test such as inoculation rabbit, cavy, mouse or dove, intramuscular injection.Dead in general 18 ~ 24h after inoculation.Injection site, presents obvious hemorrhagic oedema, and muscle cerise infiltrates; Get local edema liquid smear, dyeing, microscopy, the escherichia coli of the blunt circle in two ends can be seen, on the staining section of liver surface contact, the escherichia coli of visible long filament shape.Immuno-fluorescent antibody technique can be used for the quick diagnosis of this disease.Antidiastole is noted diagnosing with the difference of bowel oedema disease and swine plague.
Doctor trained in Western medicine control pig malignant edema is sick: to morbidity pig, will isolate in time, treat as early as possible, topical therapeutic and whole body therapeutic can be taked to combine, propagate in case expand.To sick bowel oedema disease position, can cut, expand wound, remove foreign matter and slough, repeatedly rinse with 1% ~ 2% liquor potassic permanganate or 3% hydrogen peroxide liquid, sterilization, after cleaning up, spreads penicillin, sulfa powder, sulfanilamide (SN) iodoform mixture etc. in wound; Later every day can carry out by methods of surgical routinely.And can around oedema portion, the antibacterials such as injection penicillin.According to the concrete condition of ill pig, carry out comprehensive whole body and heteropathy, as with antibiotic or and sulfa drugs fit applications, carry out the treatments such as cardiac stimulant, fluid infusion, removing toxic substances simultaneously.During treatment, edematous fluid, slough and discarded object that sick pig wound is discharged should sterilize and burn.Used treatment tool answers thorough disinfection; The pig house that sick pig pollutes and place, the disinfectant liquid disinfectants such as available 2% sodium hydroxide solution or 1% Eusol; Ight soil, remaining feed and dead corpse are buried after should burning or add sterilization liquid.
But western medical treatment pig malignant edema is sick, main application is antiviral, antibiotic etc. and other chemical synthesis class antibacterials, Long-Time Service, is easy to pathogenic strains is developed immunity to drugs, and the property of medicine declines, and easily causing pig drug residue to increase, harm animal and human body is healthy.Further, more difficult control large area infects the swinery of this disease, causes huge economic loss to culturist.Therefore, the development and application of the medicine of new type of safe just seems increasingly important.
But traditional Chinese medicine is sick in treatment pig malignant edema, not only can improve the resistance against diseases of pig, strengthen its immunity, in treatment pig malignant edema is sick, pointed strong, drug effect is gone directly focus, and inexpensive, nonhazardous, no drug residue, safe ready, complete function, be applicable to large-area applications.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for preventing the functional feed of the Chinese medicine additive of pig malignant edema, adopt the functional feed containing this Chinese medicine additive can overcome the various defects of Chinese medicine of the prior art and Western medicine, there is clearing heat and cooling blood, the effect of inducing diuresis for removing edema, improve the immunity of organisms of ill pig, curative effect is better, prolonged application has no drug resistance, drug residue free, cost price is cheap, not only can effective symptom management, the growing nutrient demand of pig can also be met.
For solving the problems of the technologies described above, the invention provides a kind of for preventing the functional feed of pig malignant edema, wherein, described functional feed comprises following raw material: corn, wheat bran, bone meal, soybean cake, vinasse, salt, oyster shell whiting, ternip, hay, bean dregs, wheat stalk, silkworm chrysalis, fish meal, rape cake, peanut cake, calcium monohydrogen phosphate, taro, antioxidant, carrot, trace element and lysine; Wherein, antioxidant is for being preferably EMQ.
Trace element comprises one or more mixtures of iron, copper, zinc, manganese, iodine.
In described functional feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 10-15 weight portion, bone meal 1-2 weight portion, soybean cake 10-20 weight portion, vinasse 5-10 weight portion, salt 0.1-0.5 weight portion, oyster shell whiting 1-2 weight portion, ternip 3-5 weight portion, hay 5-7 weight portion, bean dregs 20-30 weight portion, wheat stalk 2-4 weight portion, silkworm chrysalis 2-3 weight portion, fish meal 1-2 weight portion, rape cake 5-10 weight portion, peanut cake 5-8 weight portion, calcium monohydrogen phosphate 0.3-1 weight portion, taro 3-6 weight portion, antioxidant 0.01-0.02 weight portion, carrot 4-7 weight portion, trace element 0.02-0.5 weight portion and lysine 0.01-0.2 weight portion.
Described functional feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 10-15 weight portion, bone meal 1-2 weight portion, soybean cake 10-20 weight portion, vinasse 5-10 weight portion, salt 0.1-0.5 weight portion, oyster shell whiting 1-2 weight portion, ternip 3-5 weight portion, hay 5-7 weight portion, bean dregs 20-30 weight portion, wheat stalk 2-4 weight portion, silkworm chrysalis 2-3 weight portion, fish meal 1-2 weight portion, rape cake 5-10 weight portion, peanut cake 5-8 weight portion, calcium monohydrogen phosphate 0.3-1 weight portion, taro 3-6 weight portion, antioxidant 0.01-0.02 weight portion, carrot 4-7 weight portion, trace element 0.02-0.5 weight portion, lysine 0.01-0.2 weight portion and Chinese medicine additive 5-8 weight portion.
In described functional feed, the parts by weight of each raw material are: corn 30 weight portion, wheat bran 15 weight portion, bone meal 1 weight portion, soybean cake 10 weight portion, vinasse 5 weight portion, salt 0.3 weight portion, oyster shell whiting 1 weight portion, ternip 3 weight portion, hay 5 weight portion, bean dregs 20 weight portion, wheat stalk 2 weight portion, silkworm chrysalis 2 weight portion, fish meal 1 weight portion, rape cake 6 weight portion, peanut cake 5 weight portion, calcium monohydrogen phosphate 0.4 weight portion, taro 4 weight portion, antioxidant 0.01 weight portion, carrot 4 weight portion, trace element 0.02 weight portion, lysine 0.01 weight portion and Chinese medicine additive 6 weight portion.
Described Chinese medicine additive comprises following raw medicinal material: the dried rhizome of rehmannia, radix scrophulariae, moutan bark, Asian puccoon, folium sennae, aloe, brush-cherry seed, ramulus mori, caulis trachelospermi, heroubill, Poria cocos, coix seed, corn stigma, cucurbit, shepherd's purse, the stem pith of the rice-paper plant, pyrrosia lingua, rush, herba aristolochiae, the shell of areca nut, rhizoma nardostachyos, fevervine, rice bud, Radix Rhapontici seu Radix Echinopsis, Han dish, scabrid smallhooked hedyotis herb, white chinaure herb, gratiola, storax and clam shell.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: dried rhizome of rehmannia 10-25 weight portion, radix scrophulariae 10-20 weight portion, moutan bark 13-25 weight portion, Asian puccoon 10-24 weight portion, folium sennae 7-12 weight portion, aloe 10-20 weight portion, brush-cherry seed 14-24 weight portion, ramulus mori 10-25 weight portion, caulis trachelospermi 12-26 weight portion, heroubill 12-25 weight portion, Poria cocos 10-23 weight portion, coix seed 13-28 weight portion, corn stigma 15-30 weight portion, cucurbit 15-25 weight portion, shepherd's purse 14-28 weight portion, stem pith of the rice-paper plant 15-25 weight portion, pyrrosia lingua 10-20 weight portion, rush 10-20 weight portion, herba aristolochiae 12-24 weight portion, shell of areca nut 10-20 weight portion, rhizoma nardostachyos 10-20 weight portion, fevervine 12-22 weight portion, rice bud 10-24 weight portion, Radix Rhapontici seu Radix Echinopsis 10-23 weight portion, Han dish 10-25 weight portion, scabrid smallhooked hedyotis herb 13-27 weight portion, white chinaure herb 14-26 weight portion, gratiola 10-26 weight portion, storax 12-26 weight portion and clam shell 10-20 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: the dried rhizome of rehmannia 15 weight portion, radix scrophulariae 20 weight portion, moutan bark 25 weight portion, Asian puccoon 18 weight portion, folium sennae 7 weight portion, aloe 19 weight portion, brush-cherry seed 18 weight portion, ramulus mori 19 weight portion, caulis trachelospermi 22 weight portion, heroubill 25 weight portion, Poria cocos 23 weight portion, coix seed 28 weight portion, corn stigma 30 weight portion, cucurbit 25 weight portion, shepherd's purse 28 weight portion, the stem pith of the rice-paper plant 25 weight portion, pyrrosia lingua 20 weight portion, rush 14 weight portion, herba aristolochiae 22 weight portion, the shell of areca nut 16 weight portion, rhizoma nardostachyos 12 weight portion, fevervine 20 weight portion, rice bud 18 weight portion, Radix Rhapontici seu Radix Echinopsis 18 weight portion, Han dish 25 weight portion, scabrid smallhooked hedyotis herb 18 weight portion, white chinaure herb 19 weight portion, gratiola 16 weight portion, storax 22 weight portion and clam shell 14 weight portion.
The preparation method of described Chinese medicine additive comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 90%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 55 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.02 ~ 1.08, spraying dry, the EAT 165 ~ 175 DEG C of spray dryer, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.3 times in the dried cream powder obtained, makes particle, in 40 ~ 50 DEG C of dryings, obtains granule.
For solving the problems of the technologies described above, present invention also offers a kind of for preventing the preparation method of the functional feed of pig malignant edema, wherein, described preparation method comprises the following steps:
The first step, prepare Chinese medicine additive step: proportionally mixed by the described raw medicinal material of described Chinese medicine additive, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 90%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 55 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.02 ~ 1.08, spraying dry, the EAT of spray dryer 165 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder, in the dried cream powder obtained, add the dextrin of cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.3 times, make particle, in 40 ~ 50 DEG C of dryings, obtain Chinese medicine additive,
Second step, pulverize part raw material stage: pulverizer is put in corn, wheat bran, soybean cake, vinasse, ternip, hay, bean dregs, wheat stalk, silkworm chrysalis, rape cake, peanut cake, taro and carrot mixing and pulverizes, be ground into 100 order ~ 200 object powder;
3rd step, mixing granulation step: the raw material powder that the Chinese medicine additive granule first step obtained, second step obtain and remain other raw materials, pour into and be placed in the granulating disc of heeling condition, opening granulating disc makes it rotate, the rotating speed of granulating disc is 50 revs/min, preparation time is 15 minutes, is prepared into the spherical particle feed that diameter is 1 millimeter;
4th step, dried particles feed step: the spherical particle feed the 3rd step obtained, spreads on the mesh-belt drier with the portable stainless steel guipure of multilayer, heat drying 10 minutes, import air temperature of heating is 150 degree, and outlet air temperature is 80 degree, obtains dry feed granules.
The invention has the beneficial effects as follows: adopt the functional feed containing this Chinese medicine additive can overcome the various defects of Chinese medicine of the prior art and Western medicine, there is clearing heat and cooling blood, the effect of inducing diuresis for removing edema, improve the immunity of organisms of ill pig, curative effect is better, and prolonged application has no drug resistance, drug residue free, cost price is cheap, not only can effective symptom management, can also meet the growing nutrient demand of pig.
Detailed description of the invention
Chinese veterinarian thinks, the operation of body water liquid, depends on the promotion of gas, and the liter namely depending on temper is transferred, and the Xuan Jiangtong of lung qi adjusts, the promotion of the motive, kidney qi evaporate folding.These functions are normal, then three burnt performances certainly show disrespect on effect, and functioning of bladder passes unimpeded, normal urination, can maintain the metabolism of normal water liquid.Otherwise if because of damp and hot heresy of catching cold, the wet dipping of water, sore is contaminated, and diet, weakness due to chronic disease etc. cause above-mentioned visceral dysfunction, and three Jiao certainly show disrespect on mistake department, and functioning of bladder is unfavorable, and water retention in body, spreads unchecked skin, can send out as oedema.
The above-mentioned various cause of disease, has and singlely causes patient, also having and holds concurrently assorted and cause patient, thus making the state of an illness be tending towards complicated.The sick position of this disease is dirty at lung, spleen, kidney three, has substantial connection with the heart.Basic pathogenesis is the logical tune of impairment of dispersing and descending function of the lung, and spleen loses and transfers, and kidney loses folding, and functioning of bladder is not normal, causes water retention in body, spreads unchecked skin.In pathogenesis, lung, spleen, kidney three is dirty connects each other, influences each other, as the sick oedema of lung spleen, for a long time must and kidney, cause suffering from a deficiency of the kidney and oedema being increased the weight of; Decline of kidney-YANG, the not warm soil of fire, then spleen sun is also empty, and Earth fails to control water, then make oedema more very; Edema due to the kidney insufficiency, superinverse violates lung, then lung-QI being unable to descend, loses the function that logical tune falls in its a surname, and increases the weight of oedema.Because of outer heresy, sore, damp and hot caused oedema, sick position is many at lung spleen; Because of the oedema caused by internal injury, sick position is many at spleen kidney.Therefore, the dirty morbidity with oedema of lung spleen kidney three, is take kidney as this, take lung as mark, and be the dirty of water processed with spleen, just as " Jing Yue's complete work swelling " institute cloud: " card such as all oedema is the dirty relevant disease of lung spleen kidney three.Lid water is Zhiyin, therefore the fundamental cause of water disease being in the kidney; Aquation is in gas, therefore it is marked on lung; Water only fears soil, therefore it is built in spleen.The modern deficiency syndrome of the lung then vital QI failing to transform into essence and change water, it is insufficiency of the spleen then that Earth fails to control water and anti-gram: suffer from a deficiency of the kidney then water without main and absurd row.”
Therefore, the present invention is with clearing heat and cooling blood, inducing diuresis for removing edema is that primary treatment principle treatment pig malignant edema is sick, selects prescription: the dried rhizome of rehmannia, radix scrophulariae, moutan bark, Asian puccoon, folium sennae, aloe, brush-cherry seed, ramulus mori, caulis trachelospermi, heroubill, Poria cocos, coix seed, corn stigma, cucurbit, shepherd's purse, the stem pith of the rice-paper plant, pyrrosia lingua, rush, herba aristolochiae, the shell of areca nut, rhizoma nardostachyos, fevervine, rice bud, Radix Rhapontici seu Radix Echinopsis, Han dish, scabrid smallhooked hedyotis herb, white chinaure herb, gratiola, storax, clam shell.
Wherein, the dried rhizome of rehmannia, radix scrophulariae, moutan bark, Asian puccoon are clear, the cool blood of Radix Rhapontici seu Radix Echinopsis, Han dish, scabrid smallhooked hedyotis herb, white chinaure herb heat, nourishing yin and purging fire; Folium sennae, brush-cherry seed, aloe relax bowel, inducing diuresis for removing edema; Ramulus mori, caulis trachelospermi, heroubill, Poria cocos, coix seed, corn stigma, cucurbit, shepherd's purse, the stem pith of the rice-paper plant, pyrrosia lingua, rush, gratiola, storax, clam shell inducing diuresis for removing edema, expel the heat-evil, cool blood; Herba aristolochiae, the shell of areca nut, rhizoma nardostachyos, fevervine, rice bud invigorating the spleen excreting dampness, inducing diuresis for removing edema.Make a general survey of full side, compatibility is rigorous, reasonable, evident in efficacy.
Now each taste medicine is described below:
The dried rhizome of rehmannia: sweet, cold; The thoughts of returning home, liver, kidney channel.Shennong's Herbal: " taste is sweet, cold.Cure mainly folding to fall, exhausted muscle, in wound, by blood-arthralgia, fill out marrow, longue meat.Make soup except fever and chills and gather, except numbness.Survivor is especially good." heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, raw new, pain relieving, menstruation regulating, cool blood, hemostasis invigorate blood circulation.The dried rhizome of rehmannia is cold in nature, and function is heat clearing and blood cooling, enriching yin and nourishing kidney, promotes the production of body fluid to quench thirst, and is usually used in the diseases such as treatment hectic fever due to yin consumptive disease heat, throat pain, blood-stained sputum.By by the dried rhizome of rehmannia with fructus amomi, wine, dried orange peel for auxiliary material, repeatedly steam and shine to color blackening, quality softness is namely in order to cultivated land, and the Liuwei Dihuang Wan having cultivated land to make, be exactly famous kidney tonifying good medicine, the clinical treatment being also usually used in the diseases such as chronic nephritis, hypertension, neurasthenia, pulmonary tuberculosis.
Radix scrophulariae: taste is sweet, bitter, salty, cold nature, returns lung, stomach, kidney channel.Compendium of Material Medica: " kidney water is injured, Kidney-Yin fall, lonely positive unrooted, and send out as fire is sick, method should strengthen water with fire processed, therefore radix scrophulariae and the same merit of glutinous rehmannia.Its scrofula that disappears also is loose fire, and it is that fire is sick that Liu keeps the truth tuberculosis." " Records of Tradition Chinese and Western Medicine in Combination ": " many liquid cool in nature was the medicine of kidney tonifying warp clearly originally for radix scrophulariae, sweet and slightly bitter taste.Can enter again lung with the bright heat of clearing lung-heat man, removing toxic substances quench, is suitable for tuberculosis tuberculosis most, cough with lung heat." " Japan hanako materia medica ": " control a wind-heat poison urticaria, qi-restoratives strains, and the heart is frightened irritated, and bad weary hectic fever due to yin passes corpse perverse trend, only forgetful, detumescence poison." there is clearing heat and cooling blood, purging intense heat and detonicating, effect of enriching yin, cure mainly warm heat disease heat and ying blood, body heat, polydipsia, tongue are deep red, a spot, hectic fever due to yin labor are coughed, the cards such as constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula subcutaneous nodule, skin sore are not hindered in awake, Tianjin to dysphoria.
Moutan bark: bitter, pungent, cold nature, enters the heart, liver, kidney channel." herbal classic ": " main fever and chills, apoplexy Chi Zong, convulsion, frightened epilepsy perverse trend, except the hard hemostasis of disease stays house stomach, five viscera settling, treat carbuncle sore." " Japan hanako materia medica ": " except perverse trend, happy look, clearance natural fibre line of meat blood vessels, apocenosis, logical menstruation, disappears and flutters damage hemostasis, continuous muscles and bones, and except wandering arthritis, fall tire lower eyelid, postpartum all cold and hot vim and vigour."。Compendium of Material Medica: " nourishing Yin and falling fire, separate spot poison, throat, diuresis stasis.Descendant specially controls fire mutually with yellow tiller, does not know that the merit of the root bark of tree peony more wins also.Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it." there is the effect of clearing heat and cooling blood, promoting blood circulation to remove blood stasis, be mainly used in treatment warm heat disease heat invading xuefen, send out spot, tell nosebleed, pyreticosis later stage hot Fu Yin divides heating, deficiency of Yin osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhoea, carbuncle sore tumefacting virus, falls and flutter the card such as the pain of injury, beriberoid pyretic arthralgia.Be apt to purify the blood, and invigorate blood circulation, thus have effect of cool the blood dissipate blood stasis, make blood flow freely and not stay the stasis of blood, the absurd clearly and not row of blood-head.Therefore to diseases such as intense heat in the blood, liver kidney hyperactivity of fire and stagnation of blood stasis, all rely on as key medicine.Moutan bark can increase CF to the anesthetized dog heart, reduces cardiac output, reduces the effect of left room work done.The mouse heating that Paeonol oral disposition typhoid fever, paratyphoid vaccine cause has refrigeration function, and reduces normal mouse body temperature.
Asian puccoon: cold in nature, taste is sweet, salty, the thoughts of returning home, Liver Channel, Compendium of Material Medica: " Asian puccoon, its merit is longer than cooling and activating blood, sharp intestine and small intestine.Therefore acne rash is for going out out, blood-head poison is contained, and stool closes puckery person and with it, should go out and the purple melena person of cutting also can use.If go out and red work, and white fall into convenience person, cut compatibility and incompatibility of drugs it." " Bencao Jingshu ": " Asian puccoon is the key medicine of cool blood, therefore the gas of main trusted subordinate's heat symptoms caused by an exopathgen." be mainly used in that blood-head poison is contained, macula purple black, measles without adequate eruption, sore, eczema, scald etc.The ether of Asian puccoon, water, ethanol extract all have certain antiinflammatory action.Oral refrigeration function rabbit experiment heat pyrexia being had to mitigation of Asian puccoon decoction, its extract and pigment composition also have slight refrigeration function.
Folium sennae: sweet, bitter, cold.Return large intestine channel.Cure mainly the row that purges heat stagnant, defaecation, Li Shui.Stagnate for thermojunction, constipation is suffered from abdominal pain, oedema turgor.These product contain Sennoside A and Sennoside B, and containing green onion ketone derivatives: aloe-emodin, Chrysophanol, Rhein etc.Have folium sennae and can make medicinal discharge function and antibacterial action, folium sennae also has curariform action mask.Under gastroscope, be sprayed on gastrorrhagia place with this product infusion, direct-view has anastalsis at once as seen.
Aloe: bitter is cold in nature, removing heat from the liver, defaecation, desinsection; In addition for headache, constipation, pediatric epilepsy scared, infantile malnutrition due to digestive disturbances or intestinalparasites ulcer furuncle, burn and scald, tinea sore, hemorrhoid, atrophic rhinitis, scrofula, hepatitis, Biliary Calculi, wet tinea etc.Containing more than 200 kinds of compounds in the blade of aloe, in the middle of include 20 kinds of mineral matters, 18 seed amino acids, 12 kinds of vitamins and other various different nutrients, comprise multiple glutinous polysaccharide, aliphatic acid, Anthraquinones and flavone compound, sugar, organized enzyme etc.Anthraquinones has another name called Anthraquinone Complex, has effect of disinfection, is mainly present in juice.
Brush-cherry seed: pungent, bitter, sweet, flat.Return spleen, large intestine, small intestinl channel.Function cures mainly: moisturize laxation, lower gas, Li Shui.For intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, oedema, beriberi, difficult urination.Contained by brush-cherry seed, brush-cherry seed glucoside has strong discharge function to animal used as test.The protein component IR-A raised from brush-cherry seed and IR-B intravenously administrable have anti-inflammatory and analgesic activity.Brush-cherry seed has the significant effect promoting small bowel peristalsis. and strongly fragrant Lee's glucoside has strong discharge function to animal used as test, also has calmness and diuresis.Strongly fragrant Lee's glucoside and Senna Fructus are both large intestine purgatives, but the former side effect is little compared with the latter.
Ramulus mori: bitter, sweet, cold in nature; Return lung, Liver Channel.Supplement to the Herbal: " main abdominal pain due to acute vomiting and diarrhea is told down, and the eleventh month of the lunar calendar takes it with dense the boiling of dry person.Smooth file, takes as red sugar in large still, removes old wind and place blood." " Japan hanako materia medica ": " sharp the five internal organs, get round by bribery, lower gas, decoction; Except wind pain is perspired, and flutter damage hemostasis, and Zheng Hou An; Centipede stings snakeworm, and salt Norway applies." mulberry leaf energy dispelling wind and heat from the body, heat-clearing of inducing sweat, nourishing Yin and promoting production of body fluid; Mulberry fruit energy nourishing yin and nourishing blood, qi-restoratives is moisturized; Cortex Mori energy removing heat from lung and relieving asthma, inducing diuresis for removing edema; Ramulus mori can be clearing and activating the channels and collaterals, except numbness pain relieving; And the ash that mulberry tree burns till is white mulberry wood-ashes, also can be used for the treatment of red eye, swell pain, glaucoma, body face oedema, sitting and lying must not, the disease such as leucoderma, seborrheic dermatitis of the scalp, leprosy.
Caulis trachelospermi: bitter, is slightly cold.The thoughts of returning home, liver, kidney channel." herbal classic ": " the dead flesh carbuncle wound of main air heat, dry tongue is burnt, and carbuncle is swollen not to disappear, and mouthpiece swells, water slurry not under." Tang Materia Medica: " treat blood knot in postpartum.Pallas pit viper sore, strand is got juice and is washed it, takes juice and also goes the snake venom heart vexed; The all sores of injury by sword or axe, Feng Zhi." have and dispel rheumatism, remove obstruction in channels to relieve pain, clearing heat and cooling blood, effect of removing toxicity for detumescence, cures mainly dispelling wind and removing obstruction in the meridians, cool blood detumescence.For beriberoid pyretic arthralgia, the contraction of muscle arteries and veins, soreness of waist and knee joint, larynx numbness, carbuncle swells, injury from falling down.The dull and stereotyped trench method of this product 50% decoction, has inhibitory action to staphylococcus aureus, shigella flexneri and typhoid bacillus.
Heroubill: bitter, micro-pungent is flat.Return liver, kidney, large intestine channel." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control meridian hectic fever, dizzy, be afraid of cold, limbs are aching and tired, distaste for food, the virgin infantile malnutrition due to digestive disturbances or intestinalparasites of male heroubill woman, deficient fever do not move back person with it, diuresis, buffalo meat is for drawing." remove rheumatism, for arthralgia due to wind-dampness.The extract of the wild heroubill root of heroubill contains flavonoids, catechin, tannin, and wherein the effect of resisiting influenza virus is the most obvious to suppress copy (as influenza, herpe simplex, cowpox, the HIV-I) of multiple virus.Heroubill can suppress liver mitochondrion and MC lipid peroxidation, reduces plasma cholesterol and GOT/GPT level, suppresses the mitochondrial lipid peroxidation effect brought out by ADP and ascorbic acid.The sterile water solution of heroubill extract all has inhibitory action to shigella flexneri, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa in vitro.
Poria cocos: sweet, light is flat.Thoughts of returning home warp, lung channel, the spleen channel, kidney channel.Function: sharp water medicine; Diuretics with the action of eliminating dampness." medication heart method ": " sweet with supporing yang, the panacea of dehumidifying also for Poria cocos, the sharp key of light energy.The sweet flat yang-tonifying of taste, beneficial spleen is relieved oedema or abdominal distension through diuresis or purgation, air guide of promoting the production of body fluid." modern study shows that the effect that Poria cocos has a develop immunitypty can many-sided regulate immunologic function.Poria cocos has significant inhibitory action to staphylococcus aureus, proteus.Concoct: be soaked in water, clean, slightly steam after profit, cut skin and block in time or cut sheet, drying.Medication is avoided: the deficiency of Yin and without damp and hot, cold of insufficiency type involuntary emission, the careful clothes of collapse from qi deficiency person.Collective Notes to the Canon of Materia medica: " Chinese small iris makes for it.Dislike and hold back in vain.Fear male illiteracy, garden burnet, realgar, bark of ash, tortoise plastron.”
Coix seed: cool in nature, taste is sweet, light, returns spleen, stomach, lung channel.Be rich in the several amino acids of starch and needed by human body, there is the effect such as invigorating spleen to remove dampness, clearing away heat and eliminating pus, be applicable to have loose bowels, muscle arteries and veins contraction joint stuffiness, the disease such as oedema, beriberi, acute appendicitis, leukorrhea, the seed of Job's tears can be used as medicine, and is used for treating oedema, beriberi, splenasthenic diarrhea etc.Make skin smooth, reduce wrinkle, eliminate effect of pigment spot.Have obvious curative effect to face acne and pachylosis, in addition, it also has absorbability to ultraviolet, and its extractive matter adds in cosmetics also can reach sun-proof and effect that is antiultraviolet.Be suitable for various cancer patient, arthritis, acute and chronic nephritis oedema, cancer ascites, puffiness of the face and limbs, athlete's foot edema person, wart, beauty treatment person, juvenile flat wart, common wart, molluscum contagiosum, young acne pimple and the coarse person of other skin malnutritions, be suitable for consumptive lung disease, lung carbuncle person eats.
Corn stigma: the sweet property of taste is put down, Compendium of Material Medica: " aetite, hand, the positive bright blood system heavy prescription of foot are also.Its property is puckery, therefore all diseases before and after the main part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.The first poem of Li Zhi is said, and the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels has the difficult meeting of patient, must use surplus grain red halloysite." " book on Chinese herbal medicine is looked for the truth ": " aetite merit is identical with mountain tallow, and the matter of aetite, overweight mountain tallow, the temperature of mountain tallow, too surplus grain, must distinguish." there are the effects such as inducing diuresis to reduce edema, hypotensive, hemostasis, cholagogic, can various diseases be treated.Corn stigma can accelerate Blood Coagulation Process, improves number of platelets, can anti-hemolysis, so can to hold concurrently diuretics as hemostatic, is applied to bladder and lithangiuria, can also be used for acute hemolytic anemia.Because it has anti-allergic effects, so also may be used for treating nettle rash and asthma etc.The function of detoxification of corn stigma can be used for treating mastitis etc.In addition, corn stigma also has appetizing effect.
Cucurbit: cucurbit taste is sweet, property is smoothly nontoxic, and it is climing, palpus, leaf, flower, son, shell all can be used as medicine, and cures various diseases.Record according to ancient medical book, cucurbit taste is sweet, and property is put down, nontoxic, can do the medicine detoxified, particularly effective to various fistula sore.Climing, must the property of medicine with spend identical, numb sore can be controlled.Cucurbit flesh and son, bitter, cold in nature, poisonous, can odontopathy be controlled, gum or swollen or dew, tooth mobility.Can control appearance, edema of limbs again, urinary obstruction, nasal obstruction, and all ulcer dislikes sore.Especially the highest with the medical value of cucurbit shell, its taste is sweet, and property is put down, and nontoxic, for heat reliving and toxin-eliminating, moistening lung is convenient.
Shepherd's purse: be slightly cold is sweet, light.Energy cooling blood and hemostasis, promoting urination and removing dampness, clears liver and improve vision." modern Practical Chinese medicinal ": " hemostasis, controls empsyxis, uterine hemorrhage, miscarry hemorrhage, menorrhalgia, headache, order pain or retinal hemorrhage." shepherd's purse has the effect of similar ergot.Its medicinal extract is tried out and to be left one's post uterus or intestinal tube in animal, all in significantly shrinking.(containing the oxalic acid) intravenous injection of shepherd's purse extract or intramuscular injection (each 2-3ml, every 2-4 hour 1 time, every day the most multiplex 15ml) in various hemorrhage, have obvious anastalsis.The alcohol extract of shepherd's purse, to dog, cat, rabbit, rat intravenous injection, can produce transient blood pressure and decline, and this effect is not by 80 μ g/kg atropine institute antagonisms.
The stem pith of the rice-paper plant: taste is sweet, light, cold nature; Enter lung, stomach warp." Japan hanako materia medica ": " improving eyesight, brings down a fever, and expedites the emergence of, lower eyelid, lactogenesis." " Changsha medicine solution ": " stimulate the menstrual flow and close, treat jaundice, disappear ulcer, and sharp nose carbuncle, except vexed." clear snobbish water, logical breast.The puckery pain of main stranguria, difficult urination, oedema, jaundice, damp-warm diseases, scanty drak urine, breast was few, through closing, under band postpartum.Red for damp-warm syndrome urine, the puckery pain of gonorrhoea, oedema oliguria, agalactia.This product gas is trembled with fear lightly seasoned and body light, and enter lunar lung channel, drawing heat declines and diuresis, both treating stranguria, subsides a swelling again.Especially be suitable for the difficult urination of heat pouring, drench the puckery pain of drop, the stem pith of the rice-paper plant has diuresis, and obviously can increase urine potassium discharge rate, has effects such as promoting galactosis.Stem pith of the rice-paper plant polysaccharide has certain immunity moderation and oxidation resistant effect.
Pyrrosia lingua: cold nature, taste is sweet, bitter.Gas is micro-, the micro-puckery hardship of taste.Shennong's Herbal: " pyrrosia lingua, bitter is put down, main labor heat evil gas, and five retention of urines are obstructed, and diuresis water leads to, a stone fasten hide or leather on (sound sugarcane), on the stone of raw mountain valley." " new compilation of materia medica ": " and raw stone the moon place, pliable and tough as skin.Person on raw ancient tile, name Wa Wei, controls pouring also good." " book on Chinese herbal medicine is high former ": " pyrrosia lingua cures mainly labor heat evil gas person, and labor heat is at bone, and perverse trend is at skin, and the institute of lung kidney is main also.Five infirmity persons, the five liquid retention of urines, difficult urination also.Pyrrosia lingua helps the vital essence of lung kidney, and upper downcrossings, crystal is moistened, then the outer key of upper orifices is all logical, changes, then capable the and little facility of water channel under lung qi." function promoting diuresis for stranguria, clearing lung-heat expels the heat-evil.Control and drench pain, hematuria, lithangiuria, ephritis, uterine bleeding, dysentery, cough with lung heat, chronic bronchitis, metal-inflicted wound, ulcer.Pyrrosia lingua can strengthen the cytophagous activate the phagocytic capacity of body, and has some antitumaous effect.100% pyrrosia lingua decoction flat board burrow method, have inhibitory action to staphylococcus aureus and proteus.
Rush: to be slightly cold, sweet, light; The thoughts of returning home, lung, small intestine, urinary bladder channel." Bencao Jingshu ": " rush, its light weight leads to, and it is cold in nature, slightly sweet flavor, therefore can tonneau small intestine hot gas, descendingly goes out from urine, and small intestine is the internal organs of the heart, therefore also except the heart channel of Hang-Shaoyin heat also." function promoting diuresis for stranguria, clearing heart fire.Cure mainly: gonorrhoea, oedema, difficult urination, the puckery pain of oliguria, jaundice with damp-heat pathogen, dysphoria and insomnia, nocturnal fretfulness in infants, larynx numbness, aphthae, wound.Experiment proves that this product has diuresis, anastalsis.Treating acute and chronic pharyngitis, stomatitis.
Herba aristolochiae: bitter, temperature; Enter liver,spleen,kidney warp." Bencao Tujing ": " Xie Fenglao.Chinese ephedra then cures the wound cold sweating, with rheum officinale with taking gas." " book on Chinese herbal medicine is new again ": " cooling and activating blood, removes wind dampness removing, walks channels and collaterals, doublely controls the swollen pain of waist leg." promoting the circulation of qi dampness elimination, promoting blood circulation and stopping pain.Treat for stomachache, hernia pain, cyesedema, postpartum, vim and vigour were suffered from abdominal pain, rheumatalgia pain.The promoting flow of qi and blood circulation, pain relieving, diuresis.Cyesedema, chest is suffered from abdominal pain, colic, rheumatalgia.Herba aristolochiae, gas is invigorated blood circulation, and controls the medicine of all pains also.The gas of the person, suitable then peaceful, the inverse then vexed work of pain.As Young " side of directing at " herba aristolochiae controls the brachialgia of phlegm note, gas stays colic, and lump in the abdomen is gathered, and to globefish stomachache, postpartum, vim and vigour were suffered from abdominal pain, and he is as cyesedema, and shortness of breath is floated in face, and man's wind labor, coughs for a long time and do not heal, and knows and controls it with this medicine, peace of invariably getting into bed.Gai Weiqi is good at popular vim and vigour therefore also.See book discuss and cure mainly, only belong to the diseases such as pregnant edema during pregnancy, stomachache, wind consumptive disease, in his disease then not and here.Its reason controlled i.e., also only because bitter master is in catharsis, warm in nature being led to lives, therefore passage of invigorating blood circulation, and makes water without unfavorable, and wind removes invariably, blood work invariably, and pain to be controlled therefore also all invariably with swollen.
The shell of areca nut: taste is pungent, slightly warm in nature; Return spleen, stomach, large intestine, small intestinl channel." Kaibao Bencao ": " main cold and hot gas is made a psychological attack abdomen, and large intestine stops up poison, phlegm diaphragm, the belching of acid from stomach.And decoct with Jiang Yantong, enter thin gas medicine good." " detailed outline ": " beriberi is stopped up inverse for lowering the adverse flow of qi, aqueous vapor edema in the skin that disappears, and malignant malaria ruffian is full, and it is vexed that nausea vomiting during early pregnancy is swollen." " property of medicine class is bright ": " and the shell of areca nut, Dan Xi conventional to control lung qi syndrome characterized by dyspnea, and in oedema medicine again multiplex it, lid is also got it and is let out lung, to kill the source of water also." under gas wide in, line water detumescence.For retention of damp leading to blockage of QI, chest abdominal distension is vexed, defecates not well, oedema, beriberi, difficult urination.Rabbits infestines tonicity can be made to raise to the effect shell of areca nut decoction of intestinal smooth muscle, shrinkage amplitude reduces, and its effect can by atropine institute antagonism.
Rhizoma nardostachyos: taste is pungent, sweet, warm in nature; Return spleen, stomach warp.Compendium of Material Medica: " rhizoma nardostachyos, it is strongly fragrant that fragrance can open spleen, adds in taste medicine less, gas of being very amusing "." Japan hanako materia medica ": " control abdominal distnetion, lower gas." to have fragrance row loose for rhizoma nardostachyos, warming spleen and stomach for dispelling cold, regulating qi-flowing for relieving pain, the effect of appetizing of being amusing.Cure mainly coldness and pain in the epigastrium turgor, do not feel like eating, pectoralgia, toothache, fall the pain of injury of falling forward, beriberi edema, choleraic myospasm.Jatamansi volatile oil has faint antibacterial, wind dispelling and spasmolysis, to skin, mucous membrane without local irritation.Jatamansi is to rabbit hemostasis, and rabbit performance is to slow in reacting, sleepy, the anorexia stimulated.Rhizoma nardostachyos alcohol extract has step-down and antiulcer action.
Fevervine: property is put down, sweet, the micro-hardship of taste." the sward property of medicine is standby to be wanted ": " its head controls new internal injury, and pot is carnivorous, and qi-restoratives kidney-nourishing, except fire is enriched blood; Wash sore pain relieving, the loose poison of the heat that disappears.Its leaf beats rice with confectionery, only dysentery." " Illustrated Book on Plants ": " be wash, removing toxic substances, removes wind, heat-clearing, loose cold.Apply nameless sores or boils, and mend muscles and bones." expelling wind and activating blood flow, analgesic antidotal, promoting digestion, dehumidifying detumescence.Treatment of rheumatalgia pain, diarrhoea dysentery, dirty abdomen pain, deficiency of vital energy edema, dizzy food is few, hepatosplenomegaly, scrofula, acute appendicitis, nameless sores or boils, traumatic injury.Fevervine TA lumbar injection can suppress mouse spontaneous activity, extends yellow Jackets lengths of one's sleep, has certain sedation.Fevervine TA can suppress myenteron to shrink, and the myenteron contracture caused by energy antagonism acetylcholine.Fevervine decoction has inhibitory action to S. aureus in vitro and Fu Shigella flexneri, and medicinal extract also has bacteriostasis to staphylococcus aureus and streptococcus pneumonia.
Rice bud: nature and flavor are sweet is flat.Return spleen, stomach warp, Liver Channel." Japan hanako materia medica ": " in temperature, lower gas, appetizing, only cholera, relieving restlessness, dissolving phlegm, broken crux, can expedite the emergence of tire." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " in wide, lower gas, anti-nausea, disappear place food, only acid regurgitation acid regurgitation, antidiarrheal, the wide diaphragm of the stomach that disappears, and control married woman's milk breast and do not receive, and milk is more than." there is promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, move back effect of newborn dissipate-swelling.Cure mainly dyspepsia not disappear, abdominal distention, insufficiency of the spleen food is few, and newborn sweat smoulders, swollen breasts, and women weans.
Radix Rhapontici seu Radix Echinopsis: nature and flavor hardship is salty, cold.1. " herbal classic ": " bitter is salty, cold." 2. " not Lu ": " Great Cold, nontoxic.' 3. " book on Chinese herbal medicine is just ": " taste is micro-salty, cold in nature, slightly poisonous." return through entering stomach, large intestine channel.1. Li Gao: " hand, foot sun are bright." 2. " wood grass is from new ": " enters stomach, large intestine, logical lung, small intestine." 3. " beautiful Chinese catalpa medicine solution ": " enters kidney meridian, the liver channel of foot-Jueyin." function cures mainly clearing heat and detoxicating, detumescence and apocenosis, lactogenesis, logical muscle arteries and veins.Control ulcer carbuncle on the back, mastosis.Alactation, scrofula dislikes sore, and arthritis with fixed pain caused by dampness muscle arteries and veins is restrained, arthralgia, toxic-heat and blood stasis, hemorrhoid hemorrhage.1. " herbal classic ": " main skin heat dislikes sore subcutaneous ulcer hemorrhoid, arthritis with fixed pain caused by dampness, lower milk." 2. " not Lu ": " be only lost and is drowned, and pyretic sore is itched as numb beans, can do to bathe soup." 3. Tao Hongjing: " treats all fistula scabies." 4. " property of medicine opinion t ": " is controlled hot poison with it and is disliked sore humorously, musculus cutaneus itch urticaria." 5. supplement to the Herbal: " desinsection, washes sore scabies and uses it." 6. " Japan hanako materia medica ": " controls children's's high fever, logical small intestine, and (controlling) lets out essence, hematuria, blepharitis marginalis, acute mastitis, carbuncle on the back, scrofula, intestines wind, and apocenosis, enriches blood, and controls and flutters damage, and continuous muscles and bones, deposit sore, hemostasis is put on flesh, qualcomm meridian." 7. " Shanxi Chinese medicinal herbal ": " clearing heat and cooling blood, controls toxic-heat and blood stasis, nosebleed epistaxis, bleeding, the diseases such as warm epidemic disease."
Han dish: nature and flavor are pungent is cool.1. supplement to the Herbal: " taste is pungent, temperature, nontoxic." 2. " Kweiyang medicinal herbs among the people ": " is pungent, cool, nontoxic." 3. " Traditional Chinese Medicine in Sichuan will ": " is cool in nature.Bitter is pungent, nontoxic." 4. Guangzhou army " conventional Chinese herbal medicine handbook ": " is sweet light, cool." function cures mainly heat-clearing, diuresis, invigorates blood circulation, and stimulates the menstrual flow.Cure cold, heat is coughed, pharyngalgia, and measles is not easily sent out thoroughly, rheumathritis, jaundice, oedema, and malignant boil swells, through closing, and traumatic injury.1. supplement to the Herbal: " remove cold air, cold for a long time in abdomen, diet does not disappear, and makes us eating." 2. " detailed outline ": " sharp chest diaphragm, slit cold phlegm, pain in the chest and abdomen." 3. " classifying herbal ": " is controlled cutter and cuts axe wound, and rotten sore, myogenic, chews painting." 4. " south of the Five Ridges gather medicinal herbs record ": " and raw fish are decocted soup and take it, the heat in boning." 5. " Guizhou side among the people medicine collection ": " antipyretic diuresis.Control ascites, drench disease; Burn is controlled in external application.Serious case of furuncle is controlled in " 6. " conventional glossary of Herbs and Drugs among the people ": " external application; Venting QI-blood for oral administration.Control women's breast sick, and control cough, jaundice." 7. " Kweiyang medicinal herbs among the people ": " is clearing heat and detoxicating, relieving cough and reducing sputum.Dermatitis rhus is controlled in external application, furunculosis, and carbuncle swells." 8. Guangzhou army " conventional Chinese herbal medicine handbook ": " clearing away heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.Cure cold heating, abscess of throat, aphonia; Cough with lung heat, hemoptysis; Acute rheumatic arthritis; Oedema." 9. " Fujian Chinese herbal medicine ": " dispelling wind is shown thoroughly, regulating qi-flowing for harmonizing stomach."
Scabrid smallhooked hedyotis herb: nature and flavor are bitter, cool.1. " Nanning City's medicine will ": " sweet, cool, nontoxic." 2. " Yunnan Chinese herbal medicine ": " micro-bitterness, flat." function cures mainly clearing heat and cooling blood, and invigorating the spleen dehumidifies.Control noma, infantile malnutrition, arthralgia due to wind-dampness, 1. " Nanning City's medicine will ": " removing heat from blood, reason noma, third molar abscess.Control infantile malnutrition polydipsia, treating swelling and pain by traumatic injury." 2. " register planted by Guangxi medicine ": " leaf: cool blood." 3. " Yunnan Chinese herbal medicine ": " wines used as antirheumatic, strengthening the spleen and stomach."
White chinaure herb: in the raw hillside of habitats distribution, sylvan life and shrubbery.Distribution southwest, south China, East China are to Taiwan and other places.Chemical analysis Boenninghausenia albiflora herb contains aromatic oil 0.25%, cauline leaf oil-containing 0.3%.Aerial part contains rutin, bergapten, dictamine.The root of this product Japan mutation S.Suzuki, also containing dictamine, also containing matsukaze lactone in leaf.Nature and flavor " choosing of Yunnan Chinese herbal medicine ": " pungent light, cold.Collywobbles is controlled in " 1. function cures mainly " will planted by middle traditional Chinese medicines ": " decoction.Leaf is mashed external application and is controlled scald." 2. " choosing of Yunnan Chinese herbal medicine ": " clearing heat and cooling blood, relaxes the muscles and stimulate the blood circulation, anti-inflammatory.Cure cold, sphagitis, hepatitis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, pain in the back, traumatic injury, ecchymoma."
Gratiola: nature and flavor acid is flat.1. " classify herbal ": " taste is sweet, nontoxic." 2. " Traditional Chinese Medicine in Sichuan will ": " property is put down, taste acid, nontoxic." 3. " Jiangxi herbal medicine ": " is cold in nature, taste acid." function cures mainly expelling wind and activating blood flow, Li Shui, removing toxic substances.Control Fengshi Guanjie pain, oedema, hematuria, fall and beat, snakebite.1. " classify herbal ": " harness the Yellow River swollen." 2. " Traditional Chinese Medicine in Sichuan will ": " can fall apart blood hemostasis.Control that ephrosis Huang is swollen, snake bite and women's acute scleritis, hot infantile malnutrition due to digestive disturbances or intestinalparasites." 3. " Jiangxi herbal medicine ": " expelling wind and activating blood flow, inducing diuresis for removing edema."
Storax: nature and flavor are pungent, temperature.1. " not Lu ": " taste is sweet, temperature, nontoxic." 2. " book on Chinese herbal medicine just ": " taste is sweet pungent, warm in nature." return through entering lung, Liver Channel.1. " beautiful Chinese catalpa medicine solution ": " start with lunar lung, the liver channel of foot-Jueyin." 2. " must join book on Chinese herbal medicine ": " enters meridian of Foot-TAI YIN." 3. " book on Chinese herbal medicine is new again ": " enters spleen, stomach two warp." function cures mainly sensible, wards off dirty, opens strongly fragrant, and slit phlegm.Control soldier so to faint, phlegm heap soil or fertilizer over and around the roots is lost consciousness, frightened epilepsy, a kind of malaria, the sudden pain of trusted subordinate, mange, pernio.1. " not Lu ": " mainly ward off evil, a kind of malaria , Xian Chi.Go three worms, evil removing, make us without nightmare." 2. " book on Chinese herbal medicine just ": " desinsection poison.Treat epilepsy, only circulation of vital energy in the wrong direction pain." 3. essentials of Matea Medica: " is walked to alter, and sensiblely opens strongly fragrant, wards off all not gas just." 4. " beautiful Chinese catalpa medicine solution ": " inducing diuresis for removing edema, controls swollen , Zhen Rush, gas hematocele disease, mediation internal organs."
Clam shell: nature and flavor are salty; Cold nature.Return lung, kidney, stomach warp.Cure mainly clearing lung and eliminating phlegm; Softening and resolving hard mass; Inducing diuresis for removing edema; Relieving gastric hyperacidity to alleviate stomachache; Sore hygroscopic.Main phlegm-heat cough; Goiter and tumor; Subcutaneous nodule; Hypochondriac pain; Damp and hot oedema; Under stranguria with turbid discharge band; Stomachache pantothenic acid; Ulcer on the shank eczema.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine additive
The dried rhizome of rehmannia 15 weight portion, radix scrophulariae 20 weight portion, moutan bark 25 weight portion, Asian puccoon 18 weight portion, folium sennae 7 weight portion, aloe 19 weight portion, brush-cherry seed 18 weight portion, ramulus mori 19 weight portion, caulis trachelospermi 22 weight portion, heroubill 25 weight portion, Poria cocos 23 weight portion, coix seed 28 weight portion, corn stigma 30 weight portion, cucurbit 25 weight portion, shepherd's purse 28 weight portion, the stem pith of the rice-paper plant 25 weight portion, pyrrosia lingua 20 weight portion, rush 14 weight portion, herba aristolochiae 22 weight portion, the shell of areca nut 16 weight portion, rhizoma nardostachyos 12 weight portion, fevervine 20 weight portion, rice bud 18 weight portion, Radix Rhapontici seu Radix Echinopsis 18 weight portion, Han dish 25 weight portion, scabrid smallhooked hedyotis herb 18 weight portion, white chinaure herb 19 weight portion, gratiola 16 weight portion, storax 22 weight portion and clam shell 14 weight portion.
Its preparation method comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 4 times, mixture is the ethanol of 84%, be heated to boiling reflux 2 hours, filter, adopt percolation with the speed of 1ml per minute slowly diacolation, collect percolate, when being evaporated to 55 DEG C subsequently under vacuum 0.06Mpa, relative density is the lotion of 1.02, spraying dry, the EAT 165 DEG C of spray dryer, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 times and 0.1 times in the dried cream powder obtained, makes particle, in 40 DEG C of dryings, obtains granule.
Embodiment 2 functional feed
Corn 30 weight portion, wheat bran 15 weight portion, bone meal 1 weight portion, soybean cake 10 weight portion, vinasse 5 weight portion, salt 0.3 weight portion, oyster shell whiting 1 weight portion, ternip 3 weight portion, hay 5 weight portion, bean dregs 20 weight portion, wheat stalk 2 weight portion, silkworm chrysalis 2 weight portion, fish meal 1 weight portion, rape cake 6 weight portion, peanut cake 5 weight portion, calcium monohydrogen phosphate 0.4 weight portion, taro 4 weight portion, antioxidant 0.01 weight portion, carrot 4 weight portion, trace element 0.02 weight portion, lysine 0.01 weight portion and Chinese medicine additive 6 weight portion, the Chinese medicine additive selected is the Chinese medicine additive of embodiment 1, , wherein, antioxidant is EMQ, trace element comprises iron, copper, zinc, manganese, iodine.
Its preparation method comprises the following steps:
The first step, prepare Chinese medicine additive step: mixed in described ratio by described raw medicinal material, adding relative to the determining alcohol of 4 times, mixture is the ethanol of 84%, is heated to boiling reflux 2 hours, filter, adopt percolation with the speed of 1ml per minute slowly diacolation, collect percolate, when being evaporated to 55 DEG C subsequently under vacuum 0.06Mpa, relative density is the lotion of 1.02, spraying dry, the EAT 165 DEG C of spray dryer, leaving air temp 85 DEG C, is ground into powder subsequently, makes dried cream powder; In the dried cream powder obtained, add the dextrin of cane sugar powder relative to dried cream powder quality 0.1 times and 0.1 times, make particle, in 40 DEG C of dryings, obtain Chinese medicine additive;
Second step, pulverizes part raw material stage: pulverizer is put in corn, wheat bran, soybean cake, vinasse, ternip, hay, bean dregs, wheat stalk, silkworm chrysalis, rape cake, peanut cake, taro and carrot mixing and pulverizes, be ground into 15 object powder;
3rd step, mixing granulation step: the raw material powder that the Chinese medicine additive granule first step obtained, second step obtain and remain other raw materials, pour into and be placed in the granulating disc of heeling condition, opening granulating disc makes it rotate, the rotating speed of granulating disc is 50 revs/min, preparation time is 15 minutes, is prepared into the spherical particle feed that diameter is 1 millimeter;
4th step, dried particles feed step: the spherical particle feed the 3rd step obtained, spreads on the mesh-belt drier with the portable stainless steel guipure of multilayer, heat drying 10 minutes, import air temperature of heating is 150 degree, and outlet air temperature is 80 degree, obtains dry feed granules.
The toxicity test of Chinese medicine additive
1, trial drug: by dried rhizome of rehmannia 15g, radix scrophulariae 20g, moutan bark 25g, Asian puccoon 18g, folium sennae 7g, aloe 19g, brush-cherry seed 18g, ramulus mori 19g, caulis trachelospermi 22g, heroubill 25g, Poria cocos 23g, coix seed 28g, corn stigma 30g, cucurbit 25g, shepherd's purse 28g, stem pith of the rice-paper plant 25g, pyrrosia lingua 20g, rush 14g, herba aristolochiae 22g, shell of areca nut 16g, rhizoma nardostachyos 12g, fevervine 20g, rice bud 18g, Radix Rhapontici seu Radix Echinopsis 18g, Han dish 25g, scabrid smallhooked hedyotis herb 18g, white chinaure herb 19g, gratiola 16g, purple casserole is put in storax 22g and clam shell 14g mixing, add clear water, to clear water dipped medicinal material upper surface 4cm, soak 8 hours, be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 50 minutes dosage to liquid be slowly 300ml, filters, obtain filtrate a, for subsequent use, the residue dregs of a decoction are added clear water again, to clear water dipped medicinal material upper surface 3cm, soaks 10 hours, be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 35 minutes dosage to liquid be slowly 100ml, filters, obtain filtrate b, and filtrate a and filtrate b mixing can be obtained decoction.
2, test method: select 30 healthy mices, female, each 15 of hero, take trial drug as object, dose design is first phase in every 5 days, each issue dosage is respectively 0.10LD50,0.15LD50,0.25LD50,0.3LD 50,0.35LD50, the LD 50 that is female, male mice of this sample be 6000m part/k part BW (five dosage is 600,900,1500,1800,2100m part/k part BW).Within every 5 days, weigh once, adjustment dosage, by 0.25ml/10 part BW per os gavage.After 20 days, animal occurs without death condition, off-test, and by ascending-dose to tested material after 20 days, female, buck all occurs without death condition.Show, pharmaceutical composition of the present invention is not causing toxicity.
Contrast test
Cultivation pig has 1000 to Heze City one pig farm in 2013, and wherein the symptom of pig malignant edema appears in about 500 pigs: common eyelid, face, sometimes swelling under neck and abdomen; The auscultation of swelling position is without crepitus; Cut open inspection thickened stomach wall, mucous layer is separated with muscle layer, and edema layer can reach 1 ~ 2 cm.
Select 140 sick pigs wherein to carry out isolation experiment, be divided into 2 groups at random, functional feed group and western medicine group, often organize 70, environment of feeding is consistent.
Functional feed group: adopt the functional feed of embodiment 2 normally to feed, feed and carry out 7 days.
Western medicine group: conventional feed feeding, adopts penicillin to treat simultaneously.Penicillin is carried out intramuscular injection according to 2,400,000 units, normally feeds, feed and carry out 7 days.
Diagnosis: mostly 1. be and distribute, sex, age and kind and this disease have nothing to do; 2. manyly after having wound (bite, wound), castration etc., locally there is inflammatory edema; 3. edematous site, the initial stage by being pressed with depression, after have crepitus; Cut oedema, visible reddish yellow or bronzing foam, and there is the smelly liquid of acid; 4., after stomach lining infects, there is swelling and thicken, formed so-called " rubber stomach "; 5. as PNI, pelvic cavity serous coat and perivaginal organize hemorrhage and oedema; 6. take edematous fluid, slough or liver,spleen,kidney, lung, painstaking effort smear, Gram-positive, thalline is micro-curved in long filament shape, and gemma is larger than thalline, in oval, is positioned at thalline central authorities or near-end.Common eyelid, face, sometimes swelling under neck and abdomen; The auscultation of swelling position is without crepitus; Cut open inspection thickened stomach wall, mucous layer is separated with muscle layer, and edema layer can reach 1 ~ 2 cm.
Curative effect is passed judgment on: cure: transference cure, recovers normal; Effective: partial symptoms alleviates, basic recovery is normal; Invalid: illness is without disappearance or alleviate, or dead.
Treatment results
Table 1 is the treatment situation contrast of each group
As can be seen from Table 1, the healing of functional feed group and be effectively all better than western medicine group, can illustrate, functional feed of the present invention, treat in pig malignant edema, good effect, determined curative effect.
Table 2 is the healing of each group and the treatment time contrast of significant figure
As can be seen from Table 2, just there is result for the treatment of in the healing of the pig of functional feed and significant figure at short notice, quick western medicine group, can learn, functional feed of the present invention, treatment pig malignant edema, and treatment time is short, and treatment fast.
Table 3 is the body weight growth pattern contrast of each group
As can be seen from Table 3, in treatment simultaneously, increase body weight faster than western medicine group, can will learn the pig of functional feed group, treatment while, can also ensure the speed of growth of pig very well.
In sum, mixed feed of the present invention, treatment pig malignant edema, result for the treatment of is good, determined curative effect, and treatment is fast, is also well positioned to meet its nutritional need, ensures the speed of growth of pig.
Case: in June, 2013, there is the symptom of pig malignant edema in about 300, pig farm, one, Linyi pig: eyelid, face, sometimes swelling under neck and abdomen; The auscultation of swelling position is without crepitus; Cut open inspection thickened stomach wall, mucous layer is separated with muscle layer, and edema layer can reach 1 ~ 2 cm.Be diagnosed as pig malignant edema.Select 100 ill pigs, adopt the mixed feed of embodiments of the invention 2 to carry out diet, fed through 7 days, cure 100, cure rate reaches 100%.Follow-up is not recurred.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. one kind for preventing the functional feed of pig malignant edema, it is characterized in that, described functional feed comprises following raw material: corn, wheat bran, bone meal, soybean cake, vinasse, salt, oyster shell whiting, ternip, hay, bean dregs, wheat stalk, silkworm chrysalis, fish meal, rape cake, peanut cake, calcium monohydrogen phosphate, taro, antioxidant, carrot, trace element and lysine.
2. according to claim 1 for preventing the functional feed of pig malignant edema, it is characterized in that, in described functional feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 10-15 weight portion, bone meal 1-2 weight portion, soybean cake 10-20 weight portion, vinasse 5-10 weight portion, salt 0.1-0.5 weight portion, oyster shell whiting 1-2 weight portion, ternip 3-5 weight portion, hay 5-7 weight portion, bean dregs 20-30 weight portion, wheat stalk 2-4 weight portion, silkworm chrysalis 2-3 weight portion, fish meal 1-2 weight portion, rape cake 5-10 weight portion, peanut cake 5-8 weight portion, calcium monohydrogen phosphate 0.3-1 weight portion, taro 3-6 weight portion, antioxidant 0.01-0.02 weight portion, carrot 4-7 weight portion, trace element 0.02-0.5 weight portion and lysine 0.01-0.2 weight portion.
3. according to claim 1 and 2 for preventing the functional feed of pig malignant edema, it is characterized in that, described functional feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 10-15 weight portion, bone meal 1-2 weight portion, soybean cake 10-20 weight portion, vinasse 5-10 weight portion, salt 0.1-0.5 weight portion, oyster shell whiting 1-2 weight portion, ternip 3-5 weight portion, hay 5-7 weight portion, bean dregs 20-30 weight portion, wheat stalk 2-4 weight portion, silkworm chrysalis 2-3 weight portion, fish meal 1-2 weight portion, rape cake 5-10 weight portion, peanut cake 5-8 weight portion, calcium monohydrogen phosphate 0.3-1 weight portion, taro 3-6 weight portion, antioxidant 0.01-0.02 weight portion, carrot 4-7 weight portion, trace element 0.02-0.5 weight portion, lysine 0.01-0.2 weight portion and Chinese medicine additive 5-8 weight portion.
4. the functional feed for preventing pig malignant edema according to any one of claim 1-3, it is characterized in that, in described functional feed, the parts by weight of each raw material are: corn 30 weight portion, wheat bran 15 weight portion, bone meal 1 weight portion, soybean cake 10 weight portion, vinasse 5 weight portion, salt 0.3 weight portion, oyster shell whiting 1 weight portion, ternip 3 weight portion, hay 5 weight portion, bean dregs 20 weight portion, wheat stalk 2 weight portion, silkworm chrysalis 2 weight portion, fish meal 1 weight portion, rape cake 6 weight portion, peanut cake 5 weight portion, calcium monohydrogen phosphate 0.4 weight portion, taro 4 weight portion, antioxidant 0.01 weight portion, carrot 4 weight portion, trace element 0.02 weight portion, lysine 0.01 weight portion and Chinese medicine additive 6 weight portion.
5. the functional feed for preventing pig malignant edema according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: the dried rhizome of rehmannia, radix scrophulariae, moutan bark, Asian puccoon, folium sennae, aloe, brush-cherry seed, ramulus mori, caulis trachelospermi, heroubill, Poria cocos, coix seed, corn stigma, cucurbit, shepherd's purse, the stem pith of the rice-paper plant, pyrrosia lingua, rush, herba aristolochiae, the shell of areca nut, rhizoma nardostachyos, fevervine, rice bud, Radix Rhapontici seu Radix Echinopsis, Han dish, scabrid smallhooked hedyotis herb, white chinaure herb, gratiola, storax and clam shell.
6. the functional feed for preventing pig malignant edema according to any one of claim 1-5, is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: dried rhizome of rehmannia 10-25 weight portion, radix scrophulariae 10-20 weight portion, moutan bark 13-25 weight portion, Asian puccoon 10-24 weight portion, folium sennae 7-12 weight portion, aloe 10-20 weight portion, brush-cherry seed 14-24 weight portion, ramulus mori 10-25 weight portion, caulis trachelospermi 12-26 weight portion, heroubill 12-25 weight portion, Poria cocos 10-23 weight portion, coix seed 13-28 weight portion, corn stigma 15-30 weight portion, cucurbit 15-25 weight portion, shepherd's purse 14-28 weight portion, stem pith of the rice-paper plant 15-25 weight portion, pyrrosia lingua 10-20 weight portion, rush 10-20 weight portion, herba aristolochiae 12-24 weight portion, shell of areca nut 10-20 weight portion, rhizoma nardostachyos 10-20 weight portion, fevervine 12-22 weight portion, rice bud 10-24 weight portion, Radix Rhapontici seu Radix Echinopsis 10-23 weight portion, Han dish 10-25 weight portion, scabrid smallhooked hedyotis herb 13-27 weight portion, white chinaure herb 14-26 weight portion, gratiola 10-26 weight portion, storax 12-26 weight portion and clam shell 10-20 weight portion.
7. the functional feed for preventing pig malignant edema according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: the dried rhizome of rehmannia 15 weight portion, radix scrophulariae 20 weight portion, moutan bark 25 weight portion, Asian puccoon 18 weight portion, folium sennae 7 weight portion, aloe 19 weight portion, brush-cherry seed 18 weight portion, ramulus mori 19 weight portion, caulis trachelospermi 22 weight portion, heroubill 25 weight portion, Poria cocos 23 weight portion, coix seed 28 weight portion, corn stigma 30 weight portion, cucurbit 25 weight portion, shepherd's purse 28 weight portion, the stem pith of the rice-paper plant 25 weight portion, pyrrosia lingua 20 weight portion, rush 14 weight portion, herba aristolochiae 22 weight portion, the shell of areca nut 16 weight portion, rhizoma nardostachyos 12 weight portion, fevervine 20 weight portion, rice bud 18 weight portion, Radix Rhapontici seu Radix Echinopsis 18 weight portion, Han dish 25 weight portion, scabrid smallhooked hedyotis herb 18 weight portion, white chinaure herb 19 weight portion, gratiola 16 weight portion, storax 22 weight portion and clam shell 14 weight portion.
8. the functional feed for preventing pig malignant edema according to any one of claim 1-7, it is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 90%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 55 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.02 ~ 1.08, spraying dry, the EAT 165 ~ 175 DEG C of spray dryer, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.3 times in the dried cream powder obtained, makes particle, in 40 ~ 50 DEG C of dryings, obtains granule.
9. the preparation method of the functional feed for preventing pig malignant edema according to any one of claim 1-8, it is characterized in that, described preparation method comprises the following steps:
The first step, prepare Chinese medicine additive step: proportionally mixed by the described raw medicinal material of described Chinese medicine additive, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 90%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 55 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.02 ~ 1.08, spraying dry, the EAT of spray dryer 165 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder, in the dried cream powder obtained, add the dextrin of cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.3 times, make particle, in 40 ~ 50 DEG C of dryings, obtain Chinese medicine additive,
Second step, pulverize part raw material stage: pulverizer is put in corn, wheat bran, soybean cake, vinasse, ternip, hay, bean dregs, wheat stalk, silkworm chrysalis, rape cake, peanut cake, taro and carrot mixing and pulverizes, be ground into 100 order ~ 200 object powder;
3rd step, mixing granulation step: the raw material powder that the Chinese medicine additive granule first step obtained, second step obtain and remain other raw materials, pour into and be placed in the granulating disc of heeling condition, opening granulating disc makes it rotate, the rotating speed of granulating disc is 50 revs/min, preparation time is 15 minutes, is prepared into the spherical particle feed that diameter is 1 millimeter;
4th step, dried particles feed step: the spherical particle feed the 3rd step obtained, spreads on the mesh-belt drier with the portable stainless steel guipure of multilayer, heat drying 10 minutes, import air temperature of heating is 150 degree, and outlet air temperature is 80 degree, obtains dry feed granules.
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CN109170254A (en) * 2018-08-10 2019-01-11 佛山市三水区嘉信农业技术研究院(普通合伙) A kind of feed and preparation method thereof preventing edema disease of piglets

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