CN109164845A - Band can write the programmed cooling instrument of cooling process - Google Patents

Band can write the programmed cooling instrument of cooling process Download PDF

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Publication number
CN109164845A
CN109164845A CN201811055186.5A CN201811055186A CN109164845A CN 109164845 A CN109164845 A CN 109164845A CN 201811055186 A CN201811055186 A CN 201811055186A CN 109164845 A CN109164845 A CN 109164845A
Authority
CN
China
Prior art keywords
insulated cabinet
temperature
refrigerator
cavity
solenoid valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811055186.5A
Other languages
Chinese (zh)
Inventor
龚霄翔
王浩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hilary Stem Cell Technology Co Ltd
Original Assignee
Hilary Stem Cell Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hilary Stem Cell Technology Co Ltd filed Critical Hilary Stem Cell Technology Co Ltd
Priority to CN201811055186.5A priority Critical patent/CN109164845A/en
Publication of CN109164845A publication Critical patent/CN109164845A/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00Control of temperature
    • G05D23/19Control of temperature characterised by the use of electric means
    • G05D23/20Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature
    • G05D23/22Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element being a thermocouple

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)

Abstract

The invention discloses the programmed cooling instruments that a kind of band can write cooling process, including refrigerator, data acquisition and control device, insulated cabinet, the insulated cabinet is arranged in refrigerator inside, the insulated cabinet internal storage has cell and biological material containers, the cavity of the insulated cabinet is isolated with the cavity of refrigerator and passes through solenoid valve connection, the temperature inductor of the cavity temperature to survey insulated cabinet is provided in the insulated cabinet, the temperature inductor is acquired with data and is connect with the input terminal of control device, the data acquisition is connect with the output end of control device with solenoid valve, the data acquisition and control device include receiving unit, compare computing unit and control unit, described control unit control solenoid valve opens or closes, the cavity in cavity and refrigerator in connection or the disconnection insulated cabinet.The present invention can utilize existing ultra low temperature freezer, be not required to additional purchasing procedure cooling instrument and liquid nitrogen, can also be programmed to cell and biomaterial according to specific requirements, cost is relatively low.

Description

Band can write the programmed cooling instrument of cooling process
Technical field
The present invention relates to the journeys that the cooling instrument to cool down to biological tissue more particularly to a kind of band can write cooling process Sequence cooling instrument.
Background technique
In the preservation of cell and biological tissue, temperature-fall period breaks the motility rate after cell and tissue recovery with institutional framework Bad degree has a great impact.There are two types of current more common cooling methods: 1 uses liquid nitrogen for the programmable journey of temperature-reducing medium Sequence cooling instrument;2 program temperature reduction boxes cooperated using ultra low temperature freezer.Both cooling methods are widely used in scientific research and production While, expensive there is also programmable programmed cooling instrument device and need to consume liquid nitrogen, program temperature reduction box cannot root The problem of changing temperature lowering curve according to specific requirements.
Summary of the invention
To overcome disadvantages mentioned above, the purpose of the present invention is to provide one kind can utilize existing ultra low temperature freezer, is not required to additional Purchasing procedure cooling instrument and liquid nitrogen, the cooperation ultra low temperature freezer that cell and biomaterial can also be programmed according to specific requirements The band used can write the programmed cooling instrument of cooling process.
In order to reach the goals above, the technical solution adopted by the present invention is that: a kind of band can write the program drop of cooling process Wen Yi, including the acquisition of refrigerator, data and control device, insulated cabinet, the insulated cabinet are arranged in refrigerator inside, the insulated cabinet Portion's storage has cell and biological material containers, and solenoid valve connection is isolated with the cavity of refrigerator and is passed through to the cavity of the insulated cabinet, The temperature inductor of the cavity temperature to survey insulated cabinet is provided in the insulated cabinet, the temperature inductor is adopted with data Collection is connect with the input terminal of control device, and the data acquisition is connect with the output end of control device with solenoid valve, the data Acquisition and control device include receiving unit, compared with computing unit and control unit, receiving unit reception temperature sense The observed temperature that device is sent, the computing unit that compares is by observed temperature and the preset temperature phase in pre-set insulated cabinet Than difference being calculated, described control unit controls solenoid valve and opens, the chamber in cavity and refrigerator in insulated cabinet described in connection Body, until the temperature in the insulated cabinet reaches preset temperature, described control unit controls solenoid valve and closes.
The beneficial effect that band of the present invention can write the programmed cooling instrument of cooling process is, it is only necessary to set in existing refrigerator inside Insulated cabinet is set, and connects or disconnects by solenoid valve the cavity in cavity and insulated cabinet in refrigerator, utilizes the low of refrigerator Temperature come in the cell and biological material containers in insulated cabinet cell or biomaterial cool down;Solenoid valve opens and closes It is acquired by data with control device and is controlled, temperature inductor surveys the temperature of object to be cooled down, and comparing computing unit will receive Difference is calculated compared with the preset temperature in pre-set insulated cabinet in the observed temperature that unit receives, and control is single Member control solenoid valve is opened, the cavity connection of insulated cabinet and refrigerator, and temperature decline is accelerated in insulated cabinet, until the temperature in insulated cabinet Degree reaches preset temperature, and described control unit controls solenoid valve and closes, insulated cabinet and ultra low temperature freezer inside cavity cold air every From temperature decline slows down.It is able to cooperate existing ultra low temperature freezer to use, is not required to additional purchasing procedure cooling instrument and liquid nitrogen, it can also be right The advantages of cell and biomaterial are programmed according to specific requirements, cost is relatively low.
Preferably, the data acquisition is arranged outside refrigerator with control device.It operates and observes convenient for user.
Preferably, the solenoid valve is butterfly-type solenoid valve, and for other solenoid valves, aperture is big, and structure is simple, In the case where the no pressure difference of valve both ends, it can also work normally.
Preferably, the refrigerator is ultra low temperature freezer/low temperature refrigerator.The temperature of ultra low temperature freezer is -80 DEG C.
Preferably, the temperature inductor uses thermocouple.Compared to bi-metal temperature inductor, electric thermo-couple temperature detects model It encloses greatly, detection is accurate.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the present embodiment;
Fig. 2 is the structural schematic diagram of insulated cabinet in the present embodiment.
Specific embodiment
The preferred embodiments of the present invention will be described in detail with reference to the accompanying drawing, so that advantages and features of the invention energy It is easier to be readily appreciated by one skilled in the art, so as to make a clearer definition of the protection scope of the present invention.
Referring to shown in attached drawing 1,2, a kind of band of the present embodiment can write the programmed cooling instrument of cooling process, including refrigerator 2, Data acquisition and control device 1, insulated cabinet 3, refrigerator 2 are ultra low temperature freezer/low temperature refrigerator, and insulated cabinet 3 is arranged in refrigerator 2 Portion, 3 internal storage of insulated cabinet have cell and biological material containers 5, and the cavity of insulated cabinet 3 is isolated and is passed through with the cavity of refrigerator 2 4 connection of solenoid valve, the solenoid valve 4 in the present embodiment are butterfly-type solenoid valve.It is provided in insulated cabinet 3 to survey insulated cabinet 3 The temperature inductor 6 of cavity temperature, the temperature inductor 6 in the present embodiment use thermocouple, and temperature inductor 6 and data acquire It is connect with the input terminal of control device 1, data acquisition is connect with the output end of control device 1 with solenoid valve 4, data acquisition and control Device 1 processed includes receiving unit, compares computing unit and control unit, and receiving unit receives the reality that temperature inductor 6 is sent Testing temperature compares computing unit for observed temperature compared with the preset temperature in pre-set insulated cabinet 3, difference is calculated Value, control unit control solenoid valve 4 and open, the cavity in cavity and refrigerator 2 in connection insulated cabinet 3, until in insulated cabinet 3 Temperature reaches preset temperature, and control unit controls solenoid valve 4 and closes.
The technical concepts and features of embodiment of above only to illustrate the invention, its object is to allow be familiar with technique People understands the contents of the present invention and is implemented, and it is not intended to limit the scope of the present invention, all spiritual according to the present invention The equivalent change or modification that essence is done, should be covered by the scope of protection of the present invention.

Claims (5)

1. the programmed cooling instrument that a kind of band can write cooling process, it is characterised in that: including refrigerator (2), data acquisition and control Device (1), insulated cabinet (3), insulated cabinet (3) setting is internal in refrigerator (2), and insulated cabinet (3) internal storage has cell It is isolated and passes through solenoid valve (4) connection with the cavity of refrigerator (2) with the cavity of biological material containers (5), the insulated cabinet (3), The temperature inductor (6) of the cavity temperature to survey insulated cabinet (3), the temperature sense are provided in the insulated cabinet (3) Device (6) and data are acquired connect with the input terminal of control device (1), the output end of the data acquisition and control device (1) and Solenoid valve (4) connection, data acquisition and control device (1) include receiving unit, compared with computing unit and control unit; The receiving unit receives the observed temperature that temperature inductor (6) are sent, and the relatively computing unit is by observed temperature and in advance The preset temperature in insulated cabinet (3) set is compared, and difference is calculated, and described control unit controls solenoid valve (4) and opens, The cavity in cavity and refrigerator (2) in insulated cabinet described in connection (3), until the temperature in the insulated cabinet (3) reaches default Temperature, described control unit control solenoid valve (4) and close.
2. the programmed cooling instrument that band according to claim 1 can write cooling process, it is characterised in that: the data acquisition It is external in refrigerator (2) with control device (1) setting.
3. the programmed cooling instrument that band according to claim 1 can write cooling process, it is characterised in that: the solenoid valve It (4) is butterfly-type solenoid valve.
4. the programmed cooling instrument that band according to claim 1 can write cooling process, it is characterised in that: the refrigerator (2) For ultra low temperature freezer/low temperature refrigerator.
5. the programmed cooling instrument that band according to claim 1 can write cooling process, it is characterised in that: the temperature sense Device (6) uses thermocouple.
CN201811055186.5A 2018-09-11 2018-09-11 Band can write the programmed cooling instrument of cooling process Pending CN109164845A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811055186.5A CN109164845A (en) 2018-09-11 2018-09-11 Band can write the programmed cooling instrument of cooling process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811055186.5A CN109164845A (en) 2018-09-11 2018-09-11 Band can write the programmed cooling instrument of cooling process

Publications (1)

Publication Number Publication Date
CN109164845A true CN109164845A (en) 2019-01-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811055186.5A Pending CN109164845A (en) 2018-09-11 2018-09-11 Band can write the programmed cooling instrument of cooling process

Country Status (1)

Country Link
CN (1) CN109164845A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114739075A (en) * 2022-03-31 2022-07-12 青岛海尔生物医疗股份有限公司 Method and device for cooling program cooling instrument and program cooling instrument

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2432613Y (en) * 2000-06-20 2001-05-30 上海理工大学 Internal heating pressure jet liquid nitrogen program temp.-reducing device
CN201136864Y (en) * 2007-06-26 2008-10-22 上海交通大学医学院附属瑞金医院 Programmed cell freezing instrument with quick temperature reduction and temperature recovery functions
KR20090108398A (en) * 2008-04-11 2009-10-15 (주)티에스이 Temperature regulating module and apparatus for semiconductor device and temperature control method using the same
CN202885474U (en) * 2012-10-31 2013-04-17 河南科技学院 Programmable program cooling device
CN203204467U (en) * 2013-01-27 2013-09-18 河南中科干细胞基因工程有限公司 Programmed temperature lowering instrument
CN205250211U (en) * 2015-12-24 2016-05-25 陕西干细胞工程有限公司 Can monitor procedure cooling box of cell freezing process
CN106595176A (en) * 2017-02-06 2017-04-26 上海奥特玛特物流设备有限公司 Refrigeration container with automatic temperature control function
CN206450503U (en) * 2016-09-29 2017-08-29 广州赛莱拉干细胞科技股份有限公司 Novel program cooling box
CN207284947U (en) * 2017-09-15 2018-05-01 上海坤爱生物科技股份有限公司 A kind of programmed cell cooling box
CN207550951U (en) * 2017-12-04 2018-06-29 银丰生物工程集团有限公司 A kind of biological sample refrigerated transport case

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2432613Y (en) * 2000-06-20 2001-05-30 上海理工大学 Internal heating pressure jet liquid nitrogen program temp.-reducing device
CN201136864Y (en) * 2007-06-26 2008-10-22 上海交通大学医学院附属瑞金医院 Programmed cell freezing instrument with quick temperature reduction and temperature recovery functions
KR20090108398A (en) * 2008-04-11 2009-10-15 (주)티에스이 Temperature regulating module and apparatus for semiconductor device and temperature control method using the same
CN202885474U (en) * 2012-10-31 2013-04-17 河南科技学院 Programmable program cooling device
CN203204467U (en) * 2013-01-27 2013-09-18 河南中科干细胞基因工程有限公司 Programmed temperature lowering instrument
CN205250211U (en) * 2015-12-24 2016-05-25 陕西干细胞工程有限公司 Can monitor procedure cooling box of cell freezing process
CN206450503U (en) * 2016-09-29 2017-08-29 广州赛莱拉干细胞科技股份有限公司 Novel program cooling box
CN106595176A (en) * 2017-02-06 2017-04-26 上海奥特玛特物流设备有限公司 Refrigeration container with automatic temperature control function
CN207284947U (en) * 2017-09-15 2018-05-01 上海坤爱生物科技股份有限公司 A kind of programmed cell cooling box
CN207550951U (en) * 2017-12-04 2018-06-29 银丰生物工程集团有限公司 A kind of biological sample refrigerated transport case

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114739075A (en) * 2022-03-31 2022-07-12 青岛海尔生物医疗股份有限公司 Method and device for cooling program cooling instrument and program cooling instrument
CN114739075B (en) * 2022-03-31 2023-06-16 青岛海尔生物医疗股份有限公司 Method and device for cooling program cooling instrument and program cooling instrument

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Application publication date: 20190108