CN109125571A - A kind of Chinese medicine and preparation method thereof for treating onychomycosis - Google Patents

A kind of Chinese medicine and preparation method thereof for treating onychomycosis Download PDF

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CN109125571A
CN109125571A CN201811331861.2A CN201811331861A CN109125571A CN 109125571 A CN109125571 A CN 109125571A CN 201811331861 A CN201811331861 A CN 201811331861A CN 109125571 A CN109125571 A CN 109125571A
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onychomycosis
coloured vinegar
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陈文玉
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Abstract

The present invention relates to a kind of Chinese medicines for treating onychomycosis, it includes the component of following parts by weight: 58 parts ~ 68 parts of white Impatientis, 89 parts ~ 99 parts of kuh-seng, 76 parts ~ 86 parts of garlic powder and 852 parts ~ 867 parts of salicylic acid;It further includes at least one of the component of following parts by weight: 569 parts ~ 579 parts of benzoic acid, 155 parts ~ 165 parts of boric acid.The effect for having activating microcirculation and removing stasis medicinal, promoting menstruation deep due to Impatientis white in component;Kuh-seng has the effect of heat-clearing and damp-drying drug, anti-inflammatory antiallergic;Garlic powder has the effect of broad-spectrum antiseptic, anti-inflammatory;Salicylic acid can react with the protein in body tissue, have corrosion body effect, can clear up cortex, clean to pore;Benzoic acid and boric acid can be with antibacterials, adjusting pH value, to promote drug effect;Therefore all medicines share, compatibility is reasonable, each component pharmacological property superposition can bigger performance drug effect, when for treating onychomycosis, the fungi in onychomycosis can be killed, and grow new healthy nail again.

Description

A kind of Chinese medicine and preparation method thereof for treating onychomycosis
Technical field
The present invention relates to a kind of Chinese medicines for treating onychomycosis, and the invention further relates to a kind of Chinese medicine preparation sides for treating onychomycosis Method.
Background technique
Onychomycosis, also known as onychomycosis, Chinese medicine claims " goose chicken claw ", is by being referred to as the micro- of disease fungus now known as onychomycosis Caused by biological infection.Onychomycosis lesion starts from first distal end, lateral margin or first pleat portion, shows as first color and paramophia.Generally Start to fall ill with 1 ~ 2 finger (toe) first, severe one, which all refers to (toe) first, can suffer from.Illness deck tarnishes, and with the passing of time deck becomes It is crisp and damaged to fall off.Winter in spring is easy recurrence or aggravates, and summer and autumn is alleviated more.It is in canescence more, and tarnishes;Deck It thickens significantly, surface is uneven.Its matter ravels, and often has keratin and detrital deposit under first.Sometimes, deck can be with nail matrix point From.
There are many drugs for treating onychomycosis, can divide Western medicine and Chinese medicine, Western medicine side effect is big, at high cost;Chinese medicine side effect It is small, it is at low cost.The curative effect of drug is also different.
Summary of the invention
The invention aims to provide a kind of Chinese medicine for treating onychomycosis, Small side effects and effect is obvious.
In order to achieve the above objectives, the technical solution adopted by the present invention is that:
The present invention provides a kind of Chinese medicines for treating onychomycosis, which is characterized in that it includes the component of following parts by weight: Bai Feng 58 parts ~ 68 parts of mesona, 89 parts ~ 99 parts of kuh-seng, 76 parts ~ 86 parts of garlic powder and 852 parts ~ 867 parts of salicylic acid;It further includes following At least one of component of parts by weight: 569 parts ~ 579 parts of benzoic acid, 155 parts ~ 165 parts of boric acid.
Optimally, it includes the component of following parts by weight: 59 parts ~ 66 parts of white Impatientis, 90 parts of kuh-seng ~ 97 parts, garlic 77 parts ~ 84 parts of powder, 853 parts ~ 865 parts of salicylic acid, 570 parts ~ 577 parts of benzoic acid and 156 parts ~ 163 parts of boric acid.
Further, it further includes the component of following parts by weight: concentration is the light-coloured vinegar 2800 parts ~ 3700 of 5g/100ml Part, 1400 parts ~ 1900 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Further, it includes the component of following parts by weight: 65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, water 3500 parts of light-coloured vinegar that 864 parts of poplar acid, 576 parts of benzoic acid, 162 parts of boric acid, concentration are 5g/100ml, concentration are 30g/100ml's 1800 parts of light-coloured vinegar essence.
Further, it includes following components by weight percent: 60 parts of white Impatientis, 91 parts of kuh-seng, 78 parts of garlic powder, salicylic acid 854 parts, 571 parts of benzoic acid, 157 parts of boric acid, concentration be 5g/100ml 3000 parts of light-coloured vinegar, concentration be 30g/100ml light-coloured vinegar 1500 parts of essence.
Due to the above technical solutions, the present invention has the following advantages over the prior art:
The Chinese medicine for the treatment of onychomycosis of the invention, the effect for having activating microcirculation and removing stasis medicinal, promoting menstruation deep due to Impatientis white in component;It is bitter Ginseng has the effect of heat-clearing and damp-drying drug, anti-inflammatory antiallergic;Garlic powder has the effect of broad-spectrum antiseptic, anti-inflammatory;Salicylic acid energy and body tissue In protein react, have corrosion body effect, cortex can be cleared up, pore is cleaned;Benzoic acid and boric acid can be with Antibacterial adjusts pH value, to promote drug effect;Therefore all medicines share, compatibility is reasonable, and the superposition of each component pharmacological property being capable of bigger performance medicine Effect, when for treating onychomycosis, can kill the fungi in onychomycosis, and grow new healthy nail again.
It is a further object of the present invention to provide a kind of Chinese medicinal preparation method for treating onychomycosis, can be made Small side effects and The good Chinese medicine of therapeutic effect.
In order to achieve the above objectives, the technical solution adopted by the present invention is that:
The present invention provides a kind of Chinese medicinal preparation methods for treating onychomycosis, it includes:
Step 1 takes raw material in parts by weight: 58 parts ~ 68 parts of white Impatientis, 89 parts ~ 99 parts of kuh-seng, garlic powder 76 parts ~ 86 Part, 852 parts ~ 867 parts of salicylic acid;Take at least one of following raw materials in parts by weight again: 569 parts ~ 579 parts of benzoic acid, 155 parts ~ 165 parts of boric acid;The white Impatientis and the kuh-seng are distinguished into grinds, are then stirred with other raw material Mixture;
2500 parts ~ 4000 parts of light-coloured vinegar and concentration that concentration is 5g/100ml are added into mixture made from step 1 for step 2 For 1200 parts ~ 2100 parts of the light-coloured vinegar essence of 30g/100ml, stirring to paste.
Optimally, in step 1: 59 parts ~ 66 parts of white Impatientis, 90 parts ~ 97 parts of kuh-seng, 77 parts of garlic powder ~ 84 parts, bigcatkin willow Sour 853 parts ~ 865 parts, 570 parts ~ 577 parts of benzoic acid, 156 parts ~ 163 parts of boric acid;It is 2800 parts ~ 3700 parts of light-coloured vinegar, white in step 2 1400 parts ~ 1900 parts of acetin.
Further, in step 1,65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, benzoic acid 576 parts, 162 parts of boric acid;In step 2,3500 parts of light-coloured vinegar, 1800 parts of light-coloured vinegar essence.
Further, in step 1,60 parts of white Impatientis, 91 parts of kuh-seng, 78 parts of garlic powder, 854 parts of salicylic acid, benzoic acid 571 parts, 157 parts of boric acid;In step 2,3000 parts of light-coloured vinegar, 1500 parts of light-coloured vinegar essence.
Due to the above technical solutions, the present invention has the following advantages over the prior art:
The present invention treats the Chinese medicinal preparation method of onychomycosis, and a kind of Chinese medicine of wieldy treatment onychomycosis can be made.In Effect that white Impatientis has activating microcirculation and removing stasis medicinal, promoting menstruation deep in medicine;Kuh-seng has the effect of heat-clearing and damp-drying drug, anti-inflammatory antiallergic;Garlic powder Have effects that broad-spectrum antiseptic, anti-inflammatory;Salicylic acid can react with the protein in body tissue, there is corrosion body effect, Cortex can be cleared up, pore is cleaned;Benzoic acid and boric acid can be with antibacterials, adjusting pH value, to promote drug effect;Therefore all medicines Share, compatibility is reasonable, each component pharmacological property superposition can bigger performance drug effect, when for treating onychomycosis, onychomycosis can be killed In fungi, and grow new healthy nail again.
Specific embodiment
Technical solution of the present invention is clearly and completely described below, it is clear that described embodiment is the present invention A part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not having Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
As long as in addition, the non-structure each other of technical characteristic involved in invention described below different embodiments It can be combined with each other at conflict.
Embodiment 1
A kind of Chinese medicine for treating onychomycosis of the present embodiment, the component including following parts by weight:
65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, 162 parts of boric acid, concentration are 3500 parts of the light-coloured vinegar of 5g/100ml, 1800 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Its preparation method is:
Step 1 takes raw material in parts by weight: 65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, White Impatientis and kuh-seng are distinguished grinds, then stir to mix with other raw material by 576 parts of benzoic acid, 162 parts of boric acid Object;
Step 2,3500 parts of the light-coloured vinegar and concentration that addition concentration is 5g/100ml into mixture made from step 1 are 30g/ 1800 parts of the light-coloured vinegar essence of 100ml, stirring to paste.
Application method:
Step 1, medical adhesive tape is sticked into strip to be placed on around disease first (to prevent ointment outflow), paste treatment is coated in sick first The Chinese medicine of onychomycosis, the thick thickness from about coin of coating, i.e., about thickness 1.8mm ~ 2.1mm;
Step 2, it is cut into the square for being greater than sick first with medical adhesive tape, which is covered on the medical adhesive tape around sick first, Package disease first 4 ~ 5 days is impregnated 20 ~ 30 minutes with warm water daily, allows disease first to fully absorb drug effect, kill mollities unguium and deep layer Bacterium;
Step 3, soaked after 4 ~ 5 days, disease first is thoroughly pared off with first blade is repaired;Step 1 ~ step 3 forms a course for the treatment of;
Step 4, every a week and then the primary above-mentioned course for the treatment of of progress, four courses for the treatment of are carried out altogether, between the course for the treatment of twice Every a week.
After to the end of four courses for the treatment of, new nail can be grown.It according to circumstances can also suitably decrease or increase course for the treatment of quantity.
In the present embodiment, use concentration for the light-coloured vinegar of 5g/100ml and concentration be 30g/100ml light-coloured vinegar essence as reconciling, Chinese medicine paste is made.In other technical solutions, it can also use other conventional methods that paste Chinese medicine is made, for example be added Edible rice vinegar, vaseline, pure water etc., and can routinely parts by weight be added.In other technical solutions, concentration can also be added without For the light-coloured vinegar of 5g/100ml, and the light-coloured vinegar essence that concentration is 30g/100ml is only added, additionally incorporates suitable pure water to dilute light-coloured vinegar Essence.
Embodiment 2
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that the weight content of each component is different:
60 parts of white Impatientis, 91 parts of kuh-seng, 78 parts of garlic powder, 854 parts of salicylic acid, 571 parts of benzoic acid, 157 parts of boric acid, concentration are 3000 parts of the light-coloured vinegar of 5g/100ml, 1500 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 3
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that the weight content of each component is different:
66 parts of white Impatientis, 97 parts of kuh-seng, 84 parts of garlic powder, 865 parts of salicylic acid, 577 parts of benzoic acid, 163 parts of boric acid, concentration are 3700 parts of the light-coloured vinegar of 5g/100ml, 1900 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 4
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that the weight content of each component is different:
59 parts of white Impatientis, 90 parts of kuh-seng, 77 parts of garlic powder, 853 parts of salicylic acid, 570 parts of benzoic acid, 156 parts of boric acid, concentration are 2800 parts of the light-coloured vinegar of 5g/100ml, 1400 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 5
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that the weight content of each component is different:
68 parts of white Impatientis, 99 parts of kuh-seng, 86 parts of garlic powder, 867 parts of salicylic acid, 579 parts of benzoic acid, 165 parts of boric acid, concentration are 4000 parts of the light-coloured vinegar of 5g/100ml, 2100 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 6
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that the weight content of each component is different:
58 parts of white Impatientis, 89 parts of kuh-seng, 76 parts of garlic powder, 852 parts of salicylic acid, 569 parts of benzoic acid, 155 parts of boric acid, concentration are 2500 parts of the light-coloured vinegar of 5g/100ml, 1200 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 7
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that do not have boric acid in component;That is treatment ash The Chinese medicine of nail includes the component of following parts by weight:
65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, concentration are 5g/100ml's 3500 parts of light-coloured vinegar, 1800 parts of the light-coloured vinegar that concentration is 30g/100ml essence.
Embodiment 8
The Chinese medicine and embodiment 1 of the present embodiment treatment onychomycosis are almost the same, and difference is that do not have benzoic acid in component;Treat The Chinese medicine of onychomycosis includes the component of following parts by weight: 65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, salicylic acid 864 1800 parts of the light-coloured vinegar essence that 3500 parts of light-coloured vinegar that part, 162 parts of boric acid, concentration are 5g/100ml, concentration are 30g/100ml.
Comparative example 1
This example and embodiment 1 are almost the same, and difference is that the weight content of white Impatientis is different.Treat the Chinese medicine package of onychomycosis Include the component of following parts by weight:
75 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, 162 parts of boric acid, light-coloured vinegar 3500 parts, 1800 parts of light-coloured vinegar essence.
Comparative example 2
This example and embodiment 1 are almost the same, and difference is that the components by weight percent of kuh-seng is different.
A kind of Chinese medicine for treating onychomycosis of this example, the component including following parts by weight:
65 parts of white Impatientis, 84 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, 162 parts of boric acid, light-coloured vinegar 3500 parts, 1800 parts of light-coloured vinegar essence.
Comparative example 3
This example and embodiment 1 are almost the same, and difference is that the components by weight percent of garlic powder is different.
A kind of Chinese medicine for treating onychomycosis of this example, the component including following parts by weight:
65 parts of white Impatientis, 96 parts of kuh-seng, 71 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, 162 parts of boric acid, light-coloured vinegar 3500 parts, 1800 parts of light-coloured vinegar essence.
Comparative example 4
This example and embodiment 1 are almost the same, and difference is that do not have benzoic acid and boric acid in component.
A kind of Chinese medicine for treating onychomycosis of this example, the component including following parts by weight:
65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 3500 parts of light-coloured vinegar, 1800 parts of light-coloured vinegar essence.
Embodiment 1 ~ 8, comparative example 1 ~ 4 are subjected to clinical test.
General information: every (embodiment or comparative example) selects patient 31, wherein male 12, female 19;All examples Age minimum about 6 years old, the largest of about 67 years old in patient, the course of disease is most about 3 months short, and up to approximately 10 years, and age distribution phase in every Seemingly.
Treatment method: it is treated by above-mentioned " application method " (detailed in Example 1).
Efficacy assessment standard:
Effective: sick first disappears, and new first part is grown, and no itch, nail is complete, smooth, vivid glossy;
Effective: the sick first in part is grown, and become fragile improvement, is had no and is separated with nail matrix, and without sky is stayed, nail surface is not very smooth, gloss Degree obfuscation;
Invalid: symptom is relatively treated preceding without significant change.
1 embodiment 1 ~ 8 of table, 1 ~ 4 efficacy result of comparative example
Effective (number) Effectively (number) (number) in vain
Embodiment 1 29 2 0
Embodiment 2 28 3 0
Embodiment 3 26 5 0
Embodiment 4 24 7 0
Embodiment 5 24 7 0
Embodiment 6 23 7 1
Embodiment 7 22 9 0
Embodiment 8 22 9 0
Comparative example 1 16 10 5
Comparative example 2 18 7 6
Comparative example 3 16 10 5
Comparative example 4 15 12 4
As it can be seen from table 1 the therapeutic effect of embodiment 1 and embodiment 2 is more preferably.And if can be seen that not from comparative example Using the Chinese medicine of present invention treatment onychomycosis, curative effect decline is obvious, and the invalid case for the treatment of increases.
Typical case introduction
Old * *: male, 30 years old, people from Anhui, company's white collar started with onychomycosis for 2011, through multi-treatment but curative effect it is little, make With the embodiment of the present invention 1, thoroughly cure.
Ah *: female, 57 years old, people from Jiangsu, kept a public place clean auntie, starts within 2008 with onychomycosis, through multi-treatment but curative effect very It is micro-, using the embodiment of the present invention 1, thoroughly cure.
*: male, 32 years old, people from Jiangsu, local police station police officer started with onychomycosis for 2010, through multi-treatment but curative effect very It is micro-, using the embodiment of the present invention 1, thoroughly cure.
The above embodiments merely illustrate the technical concept and features of the present invention, and its object is to allow person skilled in the art Scholar cans understand the content of the present invention and implement it accordingly, and it is not intended to limit the scope of the present invention, it is all according to the present invention Equivalent change or modification made by Spirit Essence, should be covered by the protection scope of the present invention.

Claims (6)

1. a kind of Chinese medicine for treating onychomycosis, it includes the component of following parts by weight: 58 parts ~ 68 parts of white Impatientis, kuh-seng 89 Part ~ 99 parts, 76 parts ~ 86 parts of garlic powder and 852 parts ~ 867 parts of salicylic acid;It is characterized in that, it further includes following parts by weight At least one of component: 569 parts ~ 579 parts and 155 parts ~ 165 parts of boric acid of benzoic acid.
2. the Chinese medicine for the treatment of onychomycosis according to claim 1, which is characterized in that it further includes the group of following parts by weight Point: the light-coloured vinegar that 2800 parts ~ 3700 parts of the light-coloured vinegar that concentration be 5g/100ml and concentration are 30g/100ml is 1400 parts ~ 1900 parts smart.
3. the Chinese medicine for the treatment of onychomycosis according to claim 2, which is characterized in that it includes the group of following parts by weight Point: 65 parts of white Impatientis, 96 parts of kuh-seng, 83 parts of garlic powder, 864 parts of salicylic acid, 576 parts of benzoic acid, 162 parts of boric acid, concentration are 1800 parts of the light-coloured vinegar essence that 3500 parts of the light-coloured vinegar of 5g/100ml and concentration are 30g/100ml.
4. the Chinese medicine for the treatment of onychomycosis according to claim 2, which is characterized in that it includes following components by weight percent: Bai Feng 60 parts of mesona, 91 parts of kuh-seng, 78 parts of garlic powder, 854 parts of salicylic acid, 571 parts of benzoic acid, 157 parts of boric acid, concentration 5g/100ml 3000 parts of light-coloured vinegar, concentration be 30g/100ml light-coloured vinegar essence 1500 parts.
5. the Chinese medicinal preparation method of any treatment onychomycosis in Claims 1-4, which is characterized in that it includes following step Rapid: the benzoic acid or/and boric acid of white Impatientis, kuh-seng, garlic powder and the salicylic acid and formula ratio that take formula ratio are mixed Form mixture;The white Impatientis and the kuh-seng distinguish grinds before mixing.
6. treating the Chinese medicinal preparation method of onychomycosis according to claim 5, it is characterised in that: add also into the mixture Enter the light-coloured vinegar and light-coloured vinegar essence of formula ratio, stirring to paste.
CN201811331861.2A 2018-11-09 2018-11-09 A kind of Chinese medicine and preparation method thereof for treating onychomycosis Pending CN109125571A (en)

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CN101049362A (en) * 2007-05-09 2007-10-10 丹东源甲科技有限公司 External remedy for treating onychomycosis
CN101422556A (en) * 2008-11-25 2009-05-06 郭玉龙 Exterior-applied medicine for treating dermatopathy
CN103565916A (en) * 2013-11-07 2014-02-12 成都九芝堂金鼎药业有限公司 Traditional Chinese medicine composition for treating keratosis type tinea of feet and hands as well as preparation method thereof

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CN101049362A (en) * 2007-05-09 2007-10-10 丹东源甲科技有限公司 External remedy for treating onychomycosis
CN101422556A (en) * 2008-11-25 2009-05-06 郭玉龙 Exterior-applied medicine for treating dermatopathy
CN103565916A (en) * 2013-11-07 2014-02-12 成都九芝堂金鼎药业有限公司 Traditional Chinese medicine composition for treating keratosis type tinea of feet and hands as well as preparation method thereof

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Application publication date: 20190104