CN109115366B - Preparation method of ear temperature detector and prepared ear temperature detector - Google Patents
Preparation method of ear temperature detector and prepared ear temperature detector Download PDFInfo
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- CN109115366B CN109115366B CN201810810604.0A CN201810810604A CN109115366B CN 109115366 B CN109115366 B CN 109115366B CN 201810810604 A CN201810810604 A CN 201810810604A CN 109115366 B CN109115366 B CN 109115366B
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- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 230000001681 protective effect Effects 0.000 claims abstract description 48
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims abstract description 39
- 239000007788 liquid Substances 0.000 claims abstract description 34
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 32
- 229910021389 graphene Inorganic materials 0.000 claims abstract description 32
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims abstract description 27
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims abstract description 27
- 229920002554 vinyl polymer Polymers 0.000 claims abstract description 20
- 229920000128 polypyrrole Polymers 0.000 claims abstract description 19
- 229920006254 polymer film Polymers 0.000 claims abstract description 15
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 14
- 239000001509 sodium citrate Substances 0.000 claims abstract description 14
- 238000005507 spraying Methods 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 238000005266 casting Methods 0.000 claims abstract description 6
- 238000002156 mixing Methods 0.000 claims abstract description 3
- -1 polydimethylsiloxane Polymers 0.000 claims description 50
- 238000000034 method Methods 0.000 claims description 31
- 238000004519 manufacturing process Methods 0.000 claims description 25
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 22
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 22
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 14
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 239000011265 semifinished product Substances 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 8
- 239000000243 solution Substances 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 238000002848 electrochemical method Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 239000000178 monomer Substances 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 238000004321 preservation Methods 0.000 claims description 4
- 239000000047 product Substances 0.000 claims description 3
- 239000000523 sample Substances 0.000 claims 24
- 229920005597 polymer membrane Polymers 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 abstract description 6
- 230000035945 sensitivity Effects 0.000 abstract description 4
- 238000005259 measurement Methods 0.000 abstract 1
- 239000011259 mixed solution Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 description 6
- 230000036760 body temperature Effects 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
- 238000009529 body temperature measurement Methods 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 239000008367 deionised water Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 3
- 238000000502 dialysis Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 238000009775 high-speed stirring Methods 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000002194 synthesizing effect Effects 0.000 description 3
- QVFWZNCVPCJQOP-UHFFFAOYSA-N chloralodol Chemical compound CC(O)(C)CC(C)OC(O)C(Cl)(Cl)Cl QVFWZNCVPCJQOP-UHFFFAOYSA-N 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 231100000956 nontoxicity Toxicity 0.000 description 2
- 230000006911 nucleation Effects 0.000 description 2
- 238000010899 nucleation Methods 0.000 description 2
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- 238000000018 DNA microarray Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 238000007787 electrohydrodynamic spraying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
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- 231100000252 nontoxic Toxicity 0.000 description 1
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- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
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- 238000006467 substitution reaction Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
- G01K13/20—Clinical contact thermometers for use with humans or animals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
- G01K13/20—Clinical contact thermometers for use with humans or animals
- G01K13/25—Protective devices therefor, e.g. sleeves preventing contamination
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
- G01K13/20—Clinical contact thermometers for use with humans or animals
- G01K13/25—Protective devices therefor, e.g. sleeves preventing contamination
- G01K13/252—Protective devices therefor, e.g. sleeves preventing contamination for tympanic thermometers
Abstract
The invention relates to a preparation method of an ear temperature detector, which comprises the steps of preparing a temperature measuring device, preparing a protective sleeve and assembling the temperature measuring device and the protective sleeve. The preparation of the temperature measuring device comprises the steps of preparing graphene oxide prefabricated liquid by using graphene oxide and water; uniformly spraying the graphene oxide prefabricated liquid on a polypyrrole high polymer film to obtain a biological core chip; the preparation of the protective sleeve comprises the steps of adding thermoplastic polyurethane, polyvinyl formal and sodium citrate into N, N-dimethylformamide, and fully mixing and reacting to obtain a prefabricated mixed solution; and casting the prefabricated mixed liquid into a mold to obtain the protective sleeve. The ear temperature detector disclosed by the invention is accurate in measurement, high in sensitivity and good in biocompatibility, and can be worn in real time and carry out real-time temperature monitoring.
Description
Technical Field
The invention belongs to the field of biological electrical products, and particularly relates to an ear temperature detector.
Background
Body temperature detection is the simplest and most common thing in daily life, and both human body temperature detection and temperature detection of various large animals in animal husbandry are extremely relevant to production and life of people. Currently, various types of commercial thermometers and temperature sensors of various specifications are available on the market to accurately measure the temperature of a human body and the temperature of the surrounding environment. However, how to realize real-time monitoring of human or animal temperature is an unsolved problem, and the wearable temperature sensor can successfully break through the difficulty. At present, the methods for measuring body temperature mainly comprise a mercury thermometer for measuring the temperature of an armpit, the temperature of an anus and the temperature of an oral cavity, and an infrared thermometer for measuring the temperature of an ear and the temperature of a forehead, but the mercury thermometer and the infrared thermometer are not suitable for real-time wearable temperature monitoring. Human ears and animal inner auditory canals are used as one of the existing body temperature detection parts and have good wearing operability.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a method for manufacturing an ear temperature detector which can be worn in real time and can monitor the temperature in real time and the ear temperature detector manufactured by the method.
According to one aspect of the invention, the invention provides a method for preparing an ear temperature detector, which comprises the steps of preparing a temperature measuring device, preparing a protective sleeve and assembling the temperature measuring device and the protective sleeve;
the preparation of the temperature measuring device comprises the steps of preparing graphene oxide prefabricated liquid by using graphene oxide and water; uniformly spraying the graphene oxide prefabricated liquid on a polypyrrole high polymer film to obtain a biological core chip; bonding the core chip with one end of the lead, and wrapping with an insulating film material; connecting the other end of the wire with an electronic chip with a wireless transmission module to obtain a temperature measuring device;
the preparation of the protective sleeve comprises the steps of adding thermoplastic polyurethane and polyvinyl formal into N, N-dimethylformamide to obtain a prefabricated liquid, adding sodium citrate into the prefabricated liquid under the condition of stirring, fully mixing, and then carrying out vacuum negative-pressure air bubble removal to obtain a prefabricated mixed liquid; casting the prefabricated mixed liquid into a mold, reacting under a heat preservation condition, and curing and forming to obtain a semi-finished product protective sleeve; removing residual reagent from the semi-finished product protective sleeve and drying to obtain a finished product protective sleeve with a temperature measuring device accommodating space;
the step of assembling the temperature measuring device with the protective sleeve comprises the step of installing an electronic chip of the temperature measuring device in a temperature measuring device containing space of the protective sleeve.
Further, the concentration of the graphene oxide in the graphene oxide prefabricated liquid is 0.05-0.5 mg/L. Preferably, the concentration is 0.1-0.3 mg/L, and more preferably the concentration is 0.2 mg/L. The graphene oxide has a large number of oxygen-containing groups on the surface, has good solvent solubility and polymer affinity, and also has excellent electrical, thermal and mechanical properties.
Further, the polypyrrole polymer film is synthesized by an electrochemical method by using pyrrole monomers; and uniformly spraying the graphene oxide prefabricated liquid on the polypyrrole high polymer film by an electric spraying method. Polypyrrole is a common conductive polymer, is nontoxic, is widely used for electrodes of biological, super-capacitor and photochemical batteries, and can be combined with graphene oxide to synthesize a stable and sensitive biosensing chip. The polypyrrole high polymer synthesized by the electrochemical method has good stability and uniformity, ensures the conductivity of the conductive layer and has good stability in the air, thereby ensuring the performance stability of the core chip. According to the invention, the biochip is synthesized by selecting the electro-spraying method, so that the uniform distribution and the physical and chemical properties of the graphene oxide are ensured, the sensitivity of the sensor is improved, the operation is simple, and the technology is stable. Meanwhile, the biological core chip synthesized by the graphene oxide and the polypyrrole high polymer has high sensitivity and accurate temperature measurement.
Further, the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is (1-5): (5-10): (0.2-1). The mass ratio is preferably (1-4): (5-8): (0.2-0.7), more preferably (1-3): (5-7): (0.2-0.5), more preferably (1.5-2.5): (5.5-7): (0.25-0.3), more preferably 2: 6: 0.25. the invention adopts thermoplastic polyurethane, has wide hardness range, high mechanical strength, good processing performance, water resistance, oil resistance and good biocompatibility, so that the obtained protective sleeve has good mechanical strength and biocompatibility and obtains good processing performance when the protective sleeve is manufactured. The polyvinyl formal is selected, so that the protective sleeve has good elasticity, wear resistance, acid and alkali resistance, good toughness, mildew and moth resistance and the like, and has the most important advantages of good biocompatibility and no toxicity, so that the obtained protective sleeve has good biocompatibility and no toxicity, and the elasticity and the toughness of the protective sleeve are enhanced. The sodium citrate is used as a reagent for catalyzing the rapid nucleation reaction, so that no waste gas or waste liquid is generated in the preparation process of the protective sleeve, and the protective sleeve is environment-friendly, simple and easy to operate and low in cost. The ratio of the thermoplastic polyurethane, the polyvinyl formal and the sodium citrate directly influences the softness and the pore size of the protective sleeve, the protective sleeve obtained in the mass ratio range has high softness and proper pore size, and the protective sleeve obtained in the mass ratio range has rough texture and larger or smaller pores.
Furthermore, the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (2.5-100) g/L. Furthermore, the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is preferably (5-80) g/L, more preferably (8-60) g/L, more preferably (10-55) g/L, and more preferably (10-50) g/L. Too low a concentration affects the efficiency of the reaction, while too high a concentration directly affects the polymerization and nucleation effects, and the optimum performance can be obtained within the concentration range of the present invention.
Further, adding polydimethylsiloxane into the preheated hexane, and stirring until the polydimethylsiloxane is completely dissolved to obtain a polydimethylsiloxane hexane solution; preparing methylene acrylamide into an aqueous solution of methylene acrylamide; under stirring, the aqueous solution of methylene acrylamide was added to the hexane solution of polydimethylsiloxane, and the resulting mixture was allowed to stand at room temperature to obtain a molded insulating film material.
Further, the mass ratio of the polydimethylsiloxane to the methylene acrylamide is (2-10): (1-10). The preferable mass ratio is (3-7): (1-5), and the more preferable mass ratio is 5: 3. the polydimethylsiloxane has good viscosity, low price, simple use and good chemical inertia, and the methylene acrylamide is self-crosslinked at a high temperature or under strong light, so that the polydimethylsiloxane and the polydimethylsiloxane can be well fused to synthesize a chip insulating layer. When the polydimethylsiloxane and the methylene acrylamide are within the range of the invention, the insulating layer formed by the mutual matching reaction has the best insulating effect and the appropriate film forming time. The invention adopts polydimethylsiloxane and methylene acrylamide to prepare the insulating layer, which can obviously improve the stability and biocompatibility of the chip.
Further, the concentration of the polydimethylsiloxane in the polydimethylsiloxane hexane solution is 0.02-0.1 g/mL. The preferable concentration is 0.03-0.08 g/mL, and the more preferable concentration is 0.05 g/mL.
Further, the heat preservation condition is that the reaction is carried out for 0.5 to 2 hours at the temperature of 30 to 65 ℃, and then the curing molding is carried out for 15 to 90 minutes at the temperature of 80 to 110 ℃.
Furthermore, the wireless transmission module Bluetooth module with low power consumption and the wireless spread spectrum communication module can transmit the collected temperature information to a far end. The Bluetooth module part is mainly divided into a host part and a slave part, and can adopt a low-power Bluetooth NRF 52832. The wireless spread spectrum communication module may be a Lora module, wherein the Lora module may employ an SX1278 chip. The temperature measuring device may additionally have other modules such as a battery. In the temperature measuring device, the electronic chip, the battery and the like can be arranged in the protective sleeve, and the biological core chip wrapped by the insulating layer can be partially or completely positioned outside the protective sleeve, so that the temperature measurement is convenient.
As another aspect of the invention, the invention also provides an ear temperature detector prepared by using the preparation method of the ear temperature detector.
The invention has the advantages that:
1. the ear temperature detector has the advantages that the core chip with a special structure and composition is used, so that the temperature measurement of the ear temperature detector is accurate and the sensitivity is high.
2. The ear temperature sensor protective sleeve prepared by combining the polyvinyl formal and the thermoplastic polyurethane material can well isolate external interference factors, stabilize the surrounding environment of the temperature sensor, fix the placement position of the sensor, and simultaneously has good mechanical property, chemical corrosion resistance and biocompatibility, thereby solving the problem of real-time temperature monitoring and the problem of wearable body temperature monitoring.
3. The ear temperature detector can measure temperature in a suspension manner, does not need to be in direct contact with a measured object, and can realize remote real-time monitoring of the temperature.
Detailed Description
Exemplary embodiments of the present disclosure will be described in greater detail below, however, it should be understood that the present disclosure may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
Example 1
(1) Preparing a graphene oxide prefabricated liquid by using 20ug of graphene oxide and 100ml of water, synthesizing a polypyrrole high polymer film by 30g of pyrrole monomers through an electrochemical method, uniformly cutting the polypyrrole high polymer film into squares of 0.5cm by 0.5cm, and uniformly spraying the graphene oxide prefabricated liquid on the polypyrrole high polymer film through an electrospray method to obtain the biological core chip. 5g of polydimethylsiloxane was added to 100ml of hexane at 65 ℃ and stirred at 60rap/min for 3 hours until completely dissolved. 3g of methylene acrylamide is prepared into an aqueous solution, under the condition of stirring, the aqueous solution of the methylene acrylamide is added at the speed of 0.2ml/min, and the mixture is kept stand for 2 hours at room temperature. The formed membrane material was placed in a dialysis bag of 12-14kDa and dialyzed at room temperature for 5 days to remove the excess methylene acrylamide. Freezing and drying the membrane material at low temperature. Adhering one end of a core chip and one end of a copper wire through 502 glue, and then wrapping an insulating film material; and connecting the other end of the wire with an electronic chip with a wireless transmission module to obtain the temperature measuring device.
(2) Taking 2g of thermoplastic polyurethane and 6g of polyvinyl formal, dissolving the thermoplastic polyurethane and the polyvinyl formal in 100ml of N, N-dimethylformamide, adding 0.25g of sodium citrate under high-speed stirring, fully dissolving the thermoplastic polyurethane and the polyvinyl formal, and exhausting bubbles under vacuum negative pressure; casting the prefabricated mixed liquid into a special mould, reacting for 1 hour in a vacuum oven at 45 ℃, and curing and molding for 60 minutes at 100 ℃ to obtain a semi-finished product protective sleeve; and (3) immersing the semi-finished product protective sleeve in deionized water for 4 days to remove residual reagent, changing the liquid every day, and drying at 40 ℃ for 6 hours to obtain the protective sleeve with the temperature measuring device accommodating space.
(3) And installing an electronic chip of the temperature measuring device in the temperature measuring device accommodating space of the protective sleeve, and arranging the core chip outside the protective sleeve to obtain the ear temperature detector.
Example 2
(1) Preparing a graphene oxide prefabricated liquid by using 5ug of graphene oxide and 100ml of water, synthesizing a polypyrrole high polymer film by 30g of pyrrole monomers through an electrochemical method, uniformly cutting the polypyrrole high polymer film into squares of 0.5cm by 0.5cm, and uniformly spraying the graphene oxide prefabricated liquid on the polypyrrole high polymer film through an electrospray method to obtain the biological core chip. 5g of polydimethylsiloxane was added to 100ml of hexane at 65 ℃ and stirred at 60rap/min for 3 hours until completely dissolved. 3g of methylene acrylamide is prepared into an aqueous solution, under the condition of stirring, the aqueous solution of the methylene acrylamide is added at the speed of 0.2ml/min, and the mixture is kept stand for 2 hours at room temperature. The formed membrane material was placed in a dialysis bag of 12-14kDa and dialyzed at room temperature for 5 days to remove the excess methylene acrylamide. Freezing and drying the membrane material at low temperature. Adhering one end of a core chip and one end of a copper wire through 502 glue, and then wrapping an insulating film material; and connecting the other end of the wire with an electronic chip with a wireless transmission module to obtain the temperature measuring device.
(2) Taking 1g of thermoplastic polyurethane and 5g of polyvinyl formal, dissolving the thermoplastic polyurethane and 5g of polyvinyl formal in 100ml of N, N-dimethylformamide, adding 0.2g of sodium citrate under high-speed stirring, fully dissolving the thermoplastic polyurethane and the polyvinyl formal, and exhausting bubbles under vacuum negative pressure; casting the prefabricated mixed liquid into a special mould, reacting for 0.5 hour in a vacuum oven at the temperature of 30 ℃, and curing and molding for 15 minutes at the temperature of 80 ℃ to obtain a semi-finished product protective sleeve; and (3) immersing the semi-finished product protective sleeve in deionized water for 4 days to remove residual reagent, changing the liquid every day, and drying at 40 ℃ for 6 hours to obtain the protective sleeve with the temperature measuring device accommodating space.
(3) And installing an electronic chip of the temperature measuring device in the temperature measuring device accommodating space of the protective sleeve, and arranging the core chip outside the protective sleeve to obtain the ear temperature detector.
Example 3
(1) Preparing a graphene oxide prefabricated liquid by using 50ug of graphene oxide and 100ml of water, synthesizing a polypyrrole high polymer film by 30g of pyrrole monomers through an electrochemical method, uniformly cutting the polypyrrole high polymer film into squares of 0.5cm by 0.5cm, and uniformly spraying the graphene oxide prefabricated liquid on the polypyrrole high polymer film through an electrospray method to obtain the biological core chip. 5g of polydimethylsiloxane was added to 100ml of hexane at 65 ℃ and stirred at 60rap/min for 3 hours until completely dissolved. 3g of methylene acrylamide is prepared into an aqueous solution, under the condition of stirring, the aqueous solution of the methylene acrylamide is added at the speed of 0.2ml/min, and the mixture is kept stand for 2 hours at room temperature. The formed membrane material was placed in a dialysis bag of 12-14kDa and dialyzed at room temperature for 5 days to remove the excess methylene acrylamide. Freezing and drying the membrane material at low temperature. Adhering one end of a core chip and one end of a copper wire through 502 glue, and then wrapping an insulating film material; and connecting the other end of the wire with an electronic chip with a wireless transmission module to obtain the temperature measuring device.
(2) Dissolving 5g of thermoplastic polyurethane and 10g of polyvinyl formal in 100ml of N, N-dimethylformamide, adding 1g of sodium citrate under high-speed stirring, fully dissolving the thermoplastic polyurethane and the polyvinyl formal, and discharging bubbles under vacuum and negative pressure; casting the prefabricated mixed liquid into a special mould, reacting for 2 hours in a vacuum oven at 65 ℃, and curing and molding for 90 minutes at 110 ℃ to obtain a semi-finished product protective sleeve; and (3) immersing the semi-finished product protective sleeve in deionized water for 4 days to remove residual reagent, changing the liquid every day, and drying at 40 ℃ for 6 hours to obtain the protective sleeve with the temperature measuring device accommodating space.
(3) And installing an electronic chip of the temperature measuring device in the temperature measuring device accommodating space of the protective sleeve, and arranging the core chip outside the protective sleeve to obtain the ear temperature detector.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (24)
1. A preparation method of an ear temperature detector is characterized by comprising the following steps: the preparation method comprises the steps of preparing the temperature measuring device, preparing the protective sleeve and assembling the temperature measuring device and the protective sleeve;
the preparation of the temperature measuring device comprises the steps of preparing graphene oxide prefabricated liquid by using graphene oxide and water; uniformly spraying the graphene oxide prefabricated liquid on a polypyrrole high polymer film to obtain a biological core chip; bonding the core chip with one end of the lead, and wrapping with an insulating film material; connecting the other end of the wire with an electronic chip with a wireless transmission module to obtain a temperature measuring device;
the preparation of the protective sleeve comprises the steps of adding thermoplastic polyurethane and polyvinyl formal into N, N-dimethylformamide to obtain a prefabricated liquid, adding sodium citrate into the prefabricated liquid under the condition of stirring, fully mixing, and then carrying out vacuum negative-pressure air bubble removal to obtain a prefabricated mixed liquid; casting the prefabricated mixed liquid into a mold, reacting under a heat preservation condition, and curing and forming to obtain a semi-finished product protective sleeve; removing residual reagent from the semi-finished product protective sleeve and drying to obtain a finished product protective sleeve with a temperature measuring device accommodating space;
the step of assembling the temperature measuring device with the protective sleeve comprises the step of installing an electronic chip of the temperature measuring device in a temperature measuring device containing space of the protective sleeve.
2. The method for manufacturing an ear temperature probe according to claim 1, wherein: the concentration of the graphene oxide in the graphene oxide prefabricated liquid is 0.05-0.5 mg/L.
3. The method for manufacturing an ear temperature probe according to claim 2, wherein: the concentration of the graphene oxide in the graphene oxide prefabricated liquid is 0.1-0.3 mg/L.
4. The method for manufacturing an ear temperature probe according to claim 3, wherein: the concentration of the graphene oxide in the graphene oxide prefabricated liquid is 0.2 mg/L.
5. The method for manufacturing an ear temperature probe according to claim 1, wherein: the polypyrrole high polymer membrane is synthesized by an electrochemical method by using pyrrole monomers; and uniformly spraying the graphene oxide prefabricated liquid on the polypyrrole high polymer film by an electric spraying method.
6. The method for manufacturing an ear temperature probe according to claim 1, wherein: the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is (1-5): (5-10): (0.2-1).
7. The method for manufacturing an ear temperature probe according to claim 6, wherein: the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is (1-4): (5-8): (0.2-0.7).
8. The method for manufacturing an ear temperature probe according to claim 7, wherein: the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is (1-3): (5-7): (0.2-0.5).
9. The method for manufacturing an ear temperature probe according to claim 8, wherein: the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is (1.5-2.5): (5.5-7): (0.25-0.3).
10. The method for manufacturing an ear temperature probe according to claim 9, wherein: the mass ratio of the thermoplastic polyurethane to the polyvinyl formal to the sodium citrate is 2: 6: 0.25.
11. the method for manufacturing an ear temperature probe according to claim 1, wherein: the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (2.5-100) g/L.
12. The method for manufacturing an ear temperature probe according to claim 11, wherein: the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (5-80) g/L.
13. The method for manufacturing an ear temperature probe according to claim 12, wherein: the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (8-60) g/L.
14. The method for manufacturing an ear temperature probe according to claim 13, wherein: the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (10-55) g/L.
15. The method for manufacturing an ear temperature probe according to claim 14, wherein: the concentration of the thermoplastic polyurethane in the N, N-dimethylformamide is (10-50) g/L.
16. The method for manufacturing an ear temperature probe according to claim 1, wherein: adding polydimethylsiloxane into preheated hexane, and stirring until the polydimethylsiloxane is completely dissolved to obtain a polydimethylsiloxane hexane solution; preparing methylene acrylamide into an aqueous solution of methylene acrylamide; under stirring, the aqueous solution of methylene acrylamide was added to the hexane solution of polydimethylsiloxane, and the resulting mixture was allowed to stand at room temperature to obtain a molded insulating film material.
17. The method for manufacturing an ear temperature probe according to claim 16, wherein: the concentration of the polydimethylsiloxane in the polydimethylsiloxane hexane solution is 0.02-0.1 g/mL.
18. The method for manufacturing an ear temperature probe according to claim 17, wherein: the concentration of the polydimethylsiloxane in the polydimethylsiloxane hexane solution is 0.03-0.08 g/mL.
19. The method for manufacturing an ear temperature probe according to claim 18, wherein: the concentration of polydimethylsiloxane in the polydimethylsiloxane hexane solution was 0.05 g/mL.
20. The method for manufacturing an ear temperature probe according to claim 16, wherein: the mass ratio of the polydimethylsiloxane to the methylene acrylamide is (2-10): (1-10).
21. The method for manufacturing an ear temperature probe according to claim 20, wherein: the mass ratio of the polydimethylsiloxane to the methylene acrylamide is (3-7): (1-5).
22. The method for manufacturing an ear temperature probe according to claim 21, wherein: the mass ratio of the polydimethylsiloxane to the methylene acrylamide is 5: 3.
23. the method for manufacturing an ear temperature probe according to claim 1, wherein: the heat preservation condition is that the reaction is carried out for 0.5 to 2 hours at the temperature of 30 to 65 ℃, and then the curing molding is carried out for 15 to 90 minutes at the temperature of 80 to 110 ℃.
24. An ear temperature probe manufactured by the method for manufacturing an ear temperature probe according to any one of claims 1 to 23.
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