CN109091633A - It is a kind of for the composition and preparation method of infantile respiratory tract infection repeatedly and application - Google Patents

It is a kind of for the composition and preparation method of infantile respiratory tract infection repeatedly and application Download PDF

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CN109091633A
CN109091633A CN201811249802.0A CN201811249802A CN109091633A CN 109091633 A CN109091633 A CN 109091633A CN 201811249802 A CN201811249802 A CN 201811249802A CN 109091633 A CN109091633 A CN 109091633A
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ginseng
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查奇士
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/75Rutaceae (Rue family)
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract

The invention discloses a kind of composition for infantile respiratory tract infection repeatedly and preparation method and application, effect is inaccurate in the prior art for solution, the bad problem of safety.The present invention also provides the preparation methods of the composition.Composition of the invention is made: 5-50 parts of ginseng, 10-80 parts of Chinese yam, 10-60 parts of endothelium corneum gigeriae galli, 5-60 parts of dried orange peel, 5-30 parts of radix glycyrrhizae preparata, 5-40 parts of the root of purple-flowered peucedanum, 20-120 parts of bamboo juice of the raw material for including following parts by weight.Prescription science of the present invention, rationally, safety is taken in each component synergistic effect, the common effect for playing treatment infantile respiratory tract infection repeatedly for a long time to proportion.

Description

It is a kind of for the composition and preparation method of infantile respiratory tract infection repeatedly and application
Technical field
The invention belongs to technical field of pharmaceuticals, and in particular to a kind of composition and system for infantile respiratory tract infection repeatedly Method and application.
Background technique
Repeated respiratory infections is Pediatric Clinic common disease, and disease incidence is up to 20% or so.Refer to the infection of the upper respiratory tract in 1 year Or lower respiratory tract infection number is frequent, has been more than a certain range of respiratory tract infection.Different age diagnostic criteria is different, repeatedly Infant is more than 7 times/year within the infection of the upper respiratory tract 2 years old, and 3~5 years old children is more than 6 times/year, and 6 years old or more children are more than 5 times/ Year;Infant is more than 3 times/year within lower respiratory tract infection 2 years old repeatedly, and 3~5 years old children is more than 2 times/year, and children are super within 6 years old or more Cross 2 times/year of diagnosable repeated respiratory infections.
There are many reason of causing infantile respiratory tract infection repeatedly.Children are in the growth hair phase, and each allelotaxis is not yet Maturation, various regulatory functions are still unstable, strong to the neurological susceptibility of disease, and the stress function is low.After the onset of children, fruit sputum is discharged not It is unobstructed, the recession of inflammation or even sputum can be hindered to become the culture medium of bacterial reproduction in vivo, cause secondary infection, aggravate disease Feelings.Dyspepsia is pathogenic factor as pathological product, can induce children and send out multiple respiratory tract infection.
In the prior art, have and infantile respiratory tract infection repeatedly is controlled using bronchodilator.But children's bronchus is smooth Flesh and nervous system development are not mature enough, poor to bronchodilator sensibility, and toxic reaction is strong, especially Western medicine ammonia tea Alkali, Chinese medicine Chinese ephedra easily cause children irritated, and device is bored, irritability, or even the nervous systems excitability such as twitch increases symptom.
In addition there are anti-using the treatment children such as semen armeniacae amarae, the tuber of pinellia, asarum, rhizoma zingiberis, Aconitum drug, realgar, diuretics Multiple respiratory tract infection.But semen armeniacae amarae, toxic, amygdalin generates a small amount of hydrogen cyanide after decomposing, and can resist coughing centre and play town Cough antiasthmatic effect, but sputum is made to be not easy to be discharged.Diuretics such as rhizoma alismatis, umbellate pore furgus, have stronger diuresis, can hurt the saliva of children Liquid damages healthy tendency.The tuber of pinellia: pungent-warm is dry, therefore children cough should not use long.Asarum: with poison, pharmacological property is more fierce, and consumption hurts healthy tendency. Rhizoma zingiberis: modern pharmacological studies have shown that the directly excited heart of rhizoma zingiberis energy, has excitation to vasomotor center.Because of children's heart rate Quickly, as used drug excitement heart, heart rate can be accelerated, lead to the myocardial ischemia even appearance of heart failure.It is monkshood, radix aconiti agrestis, attached Son contains aconitine ingredient, and poisoning is mainly shown as the symptom of nerve and cardiovascular system.The main component of realgar is three oxygen Change two arsenic, can lead to cell death, thus causes the function and organic disease of each system of body.Also there is the report using pappy shell Road, but children are especially sensitive to morphine, and codeine is to inhibit coughing centre and play antitussive effect, and sputum is made to be not easy to be discharged.
In addition, also allergic symptom occur to common Chinese medicine such as Radix Isatidis, radix paeoniae rubra, Poria cocos etc. in Yi Yinqi children, show as complete Body and local skin play bean cotyledon size erythema, itch, swelling.Closely there is contact Poria cocos to cause the report of allergic bronchial asthma.
Therefore it provides a kind of composition, can be used for infantile respiratory tract infection repeatedly, and definite effect, adverse reaction is small, at For those skilled in the art's urgent problem to be solved.
Summary of the invention
Technical problem solved by the present invention is providing a kind of composition for infantile respiratory tract infection repeatedly, solve existing There is effect in technology inaccurate, the bad problem of safety.
The present invention also provides the preparation methods of the composition.
The application that invention further provides the compositions in the drug or food for preparing infantile respiratory tract infection repeatedly.
The technical solution adopted by the invention is as follows:
A kind of composition for infantile respiratory tract infection repeatedly of the present invention, by the raw material including following parts by weight It is made: 5-50 parts of ginseng, 10-80 parts of Chinese yam, 10-60 parts of endothelium corneum gigeriae galli, 5-60 parts of dried orange peel, 5-30 parts of radix glycyrrhizae preparata, 5-40 parts of the root of purple-flowered peucedanum, 20-120 parts of bamboo juice.
Preferably, by including that the raw material of following parts by weight is made: 8-35 parts of ginseng, 15-65 parts of Chinese yam, endothelium corneum gigeriae galli 15-50 Part, 8-45 parts of dried orange peel, 8-25 parts of radix glycyrrhizae preparata, 8-35 parts of the root of purple-flowered peucedanum, 25-105 parts of bamboo juice.
Preferably, by including that the raw material of following parts by weight is made: 10 parts of ginseng, 20 parts of Chinese yam, 20 parts of endothelium corneum gigeriae galli, dried orange peel 10 Part, 10 parts of radix glycyrrhizae preparata, 10 parts of the root of purple-flowered peucedanum, 30 parts of bamboo juice.
Preferably, by including that the raw material of following parts by weight is made: 30 parts of ginseng, 60 parts of Chinese yam, 40 parts of endothelium corneum gigeriae galli, dried orange peel 40 Part, 20 parts of radix glycyrrhizae preparata, 30 parts of the root of purple-flowered peucedanum, 100 parts of bamboo juice.
Preferably, the dosage of the raw material meet one of following 3 kinds of situations or more than one:
Ginseng/(dried orange peel+root of purple-flowered peucedanum) is 0.3-0.7;
Radix glycyrrhizae preparata/(Chinese yam+bamboo juice) is 0.1-0.3;
(ginseng+endothelium corneum gigeriae galli)/bamboo juice is 0.48-1.5.
Preferably, the dosage of the raw material meet one of following 3 kinds of situations or more than one:
Ginseng/(dried orange peel+root of purple-flowered peucedanum) is 0.4-0.6;
Radix glycyrrhizae preparata/(Chinese yam+bamboo juice) is 0.12-0.25;
(ginseng+endothelium corneum gigeriae galli)/bamboo juice is 0.6-1.1.
Preferably, the composition be using ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum, bamboo juice as bulk pharmaceutical chemicals, Pharmaceutically acceptable auxiliary material is added, the preparation being conventionally prepared.
Preferably, the preparation is oral preparation.
A kind of preparation method of composition for infantile respiratory tract infection repeatedly of the present invention, comprising the following steps:
Step 1: preparation raw material by weight;
Step 2. adds water to cook ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum, filtering, and bamboo is added in filtrate Drip, after mixing, be concentrated, packing, sterilizing to get.
Composition of the present invention is in preparation for the application in the drug of infantile respiratory tract infection repeatedly, food.This Ginseng described in invention is the dry root and rhizome of Araliaceae ginseng Panax ginseng C.A.Mey..More than autumn Excavation is cleaned and is dried or dried.Cultivation is commonly called as " garden ginsent ";Sow the title " hayashishita grown naturally under mountain forest wild state Wild ginseng " is practised and claims " seed sea ".Ginseng is sweet in flavor, slight bitter, tepor.Returns spleen, lung, the heart, kidney channel.Function with the major functions: reinforce vital energy, multiple arteries and veins Prevent prolapse reinforces the spleen to benefit the lung, shengjin nourishing, tranquilize the mind and promote the intelligence.It to be taken off for physically weak, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, saliva wound Thirsty, Heat Diabetes, deficiency of qi and blood, prolonged illness void is thin, insomnia of palpitating with fear, impotence palace cold.
Heretofore described Chinese yam is the dry root of Dioscoreaceae plant Chinese yam Dioscorea opposita Thun b. Stem.Taste sweet and neutral.Returns spleen, lung, kidney channel.Function with the major functions: tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.For spleen eating less, long It rushes down incessantly, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, let out Rush down loose stool, leukorrhea.
Heretofore described endothelium corneum gigeriae galli is Phasianidae animal family chicken Callus gallus domesticus Brisson's Dry inner wall of sandbag.After killing chicken, chicken gizzard is taken out, immediately inner wall under capsule, cleaning, drying.Taste sweet and neutral.Returns spleen, stomach, small intestine, bladder Through.Function with the major functions: stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil.For dyspepsia, vomiting dysentery, infantile malnutrition, the enuresis, Spermatorrhea, the puckery pain of urolithiasis, distension of gallbladder, hypochondriac pain.
Heretofore described dried orange peel is rutaceae orange Citrus reticulata Blanco and its variety Dry mature skin.Medicinal material is divided into " dried orange peel " and " citrus chachiensis hortorum ".Harvesting ripe fruit strips pericarp, sun drying or low temperature drying. It is bitter, acrid in flavour and warm in nature.Return lung, the spleen channel.Function with the major functions: regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, cough Abundant expectoration.
Heretofore described radix glycyrrhizae preparata is the Preparation process product of Radix Glycyrrhizae.Taste sweet and neutral.Return heart, lung, spleen, stomach meridian.Function with The major functions: tonifying spleen stomach function regulating, Yiqi and vein recovery.Weak, fatigue and weakness, severe palpilation, knotted pulse for spleen helmet.Wherein, Radix Glycyrrhizae is pulse family plant Object Radix Glycyrrhizae Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza inflata Bat. or glycyrrhiza glabra The dry root and rhizome of Glycyrrhiza glabra L..
The heretofore described root of purple-flowered peucedanum is umbelliferae RADIX PEUCEDANI Peucedanum praeruptorum Dunn's Dry root.Excavation when winter to secondary spring cauline leaf withers or do not take out scape, removes fibrous root, cleans, sun drying or low temperature drying.Bitter, It is pungent, it is slightly cold.It is distributed in lung channel.Function with the major functions: lowering the adverse-rising QI to resolve phlegm, relieve heat heat-clearing.Full for phlegm heat panting, slightly phlegm Huang is thick, cough due to wind-heat evil's phlegm It is more.Heretofore described bamboo juice is Gramineae plant phyllostachys glauca McClure Phyllostachys glauca McClure, net bamboo The liquid leached naturally after Phyllostachys nuda McClure and the fresh bar for belonging to several plants are heated.It is sweet in flavor, property It is cold.Have the function of clearing heat and eliminating phlegm, be used for cough with lung heat's abundant expectoration, pant uncomfortable in chest, apoplexy tongue is strong, accumulation and obstruction of sputum, and children's phlegm heat is frightened Wind.
Pharmaceutically acceptable auxiliary material mentioned in the present invention, including " medicinal excipient handbook " (American Pharmaceutical Association, In October, 1986), Chemical Industry Press publish " pharmaceutic adjuvant handbook " (Handbook of Pharmaceutical Excipients, original work fourth edition) or " pharmaceutical necessities are complete works of " (Sichuan Publishing Group, Sichuan science tech publishing house publish, In January, 2006) listed by auxiliary material, but be not limited to these auxiliary materials.
Compared with prior art, the invention has the following advantages:
Prescription science of the present invention, proportion is monarch with ginseng, Chinese yam is minister, and the root of purple-flowered peucedanum, bamboo juice, dried orange peel, endothelium corneum gigeriae galli are rationally Assistant, radix glycyrrhizae preparata are to make medicine, each component synergistic effect, and the common effect for playing treatment infantile respiratory tract infection repeatedly is long-term to take With safety.
Ginseng is sweet in flavor in the present invention, slight bitter, tepor, returns spleen, lung, the heart, kidney channel;It reinforces vital energy, reinforces the spleen to benefit the lung;Chinese yam taste Sweet and neutral, returns spleen, lung, kidney channel, tonifying spleen nourishing the stomach, engender liquid and benefic lung.Chinese yam and ginseng compatibility, it is common to play solid centralizing qi, benifit lung spleen The function of kidney.It is root of purple-flowered peucedanum bitter in the present invention, pungent, it is slightly cold, it is distributed in lung channel;Lowering the adverse-rising QI to resolve phlegm, relieve heat heat-clearing.The root of purple-flowered peucedanum and tonic ginseng, Chinese yam compatibility, the intrusion of preventing diseases caused by external factors ailment said due to cold or exposure and influenza virus.Radix glycyrrhizae preparata taste sweet and neutral, return heart, lung, spleen, stomach meridian;With antiallergy Effect, effectively prevent bronchial asthma breaking-out.Bamboo juice is sweet in flavor, cold in nature, clearing heat and eliminating phlegm;It can increase bronchus ciliary movement, Sputum is discharged from trachea-bronchial epithelial cell.Dried orange peel bitter, acrid in flavour and warm in nature, return lung, the spleen channel, regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm;Endothelium corneum gigeriae galli taste Sweet and neutral, returns spleen, stomach, small intestine, bladder meridian, stomach strengthening and digestion promoting.Dried orange peel and endothelium corneum gigeriae galli compatibility, play disperse accumulation altogether and help fortune, anti-dyspepsia It induces children and sends out multiple respiratory tract infection.
In the present invention, ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, bamboo juice have long-term edible history, and safety is good It is good.
Present invention employs oral preparations, facilitate production, storage, transport, carry and take.
Specific embodiment
Below with reference to embodiment, the invention will be further described, and mode of the invention includes but are not limited to following implementation Example.
Embodiment 1
Present embodiment discloses the raw material of composition of the invention compositions, are specifically shown in Table 1:
Table 1
Embodiment 2
Present embodiment discloses the preparation method of composition of the invention, specifically:
Step 1: preparation raw material by weight;
Step 2. adds water to cook ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum three times, adds 8 times of amount decoctings every time It boils 2 hours, filters, bamboo juice is added into filtrate for merging filtrate, and after mixing, being concentrated into density is 1.08-1.12 (60 DEG C) Concentrate, packing, sterilizing to get.
In the present embodiment, after 0.3% potassium sorbate can also being added in concentrate, then dispenses, sterilizes.
Embodiment 3
Present embodiment discloses the preparation method of composition of the invention, specifically:
Step 1: preparation raw material by weight;
Ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum are added 65%-85% ethanol solution refluxing extraction by step 2. Three times, the ethanol solutions of 6 times of amounts are added to extract every time 1.5 hours, filtering, merging filtrate, after recycling ethyl alcohol, addition bamboo juice mixing is equal It is even, be further concentrated to density be 1.08-1.12 (60 DEG C) concentrate, packing, sterilizing to get.
In the present embodiment, after 0.3% sorbitol can also being added in concentrate, then dispenses, sterilizes.
Embodiment 4
Present embodiment discloses the preparation method of composition of the invention, specifically:
Step 1: preparation raw material by weight;
Ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum are added water to cook secondary, each plus 6 times of amount decoctings by step 2. It boils 1 hour, filters, bamboo juice is added into filtrate for merging filtrate, and after mixing, being concentrated into density is 1.25-1.30 (60 DEG C) Thick paste, the dextrin of 2 times of quality of thick paste is added, is uniformly mixed, wet granulation is dry, packing to get.
Embodiment 5
Using the formula of serial number 8 in table 1, using the method for embodiment 2, mouth made of potassium sorbate is not added in preparation Take liquid.The every ml of gained sample is equivalent to crude drug in whole 2.5g.
Embodiment 6
Using the formula of serial number 9 in table 1, using the method for embodiment 3, mouth made of potassium sorbate is not added in preparation Take liquid.The every ml of gained sample is equivalent to crude drug in whole 4g.
Embodiment 7
Present embodiment discloses clinical applications of the invention.
Xu of case 1. certain, male 9 months 3 years old, goes to a doctor April 5 2017 date.
Present illness history: every month will catch a cold 1 time after children 1 years old, and cardinal symptom is exactly first to have a fever, and burning is stepped back to be sent out with regard to tonsillotome Inflammation, and cough, it coughs very violent.Need continuous oral and injection drug that could fully recover more than 1 week.
Check: ordinary circumstance is fine, and 36.6 DEG C of body temperature, pharynx is slightly red, and cardiopulmonary are normal, and for abdomen without tenderness, remaining is normal.
Diagnosis: repeated respiratory infections.
Treatment: the sample prepared using the embodiment of the present invention 5 is taken orally, sooner or later primary, bfore meals, each 1ml.January For 1 course for the treatment of.
Curative effect: after the medication of this infant, three middle of the month only catch a cold 1 time, and respiratory tract infection does not occur.And symptom is very light, only table It is now runny nose, does not have a fever, tonsillotome is not red and swollen, does not cough, and oral cold drug is fully recovered.9 middle of the month have suffered from afterwards catches a cold twice, Respiratory tract infection does not occur.Symptom is very light, does not have a fever, and tonsillotome is not red and swollen, does not cough, and oral cold drug is fully recovered.
Embodiment 8
Present embodiment discloses clinical applications of the invention.
Case 2
1. Chen of case, female 4 months 5 years old, go to a doctor May 2 2017 date.
Present illness history: having suffered from Bronchopneumonia from 2 years old and be hospitalized, and will be hospitalized every year 2 times, usually monthly catches a cold 1 time, after flu With regard to cough, pant, have phlegm, need continuous oral and injection drug could fully recover more than 1 week.
Check: ordinary circumstance is fine, and for tonsillotome without enlargement, cardiopulmonary are normal, and for abdomen without tenderness, remaining is normal.
Diagnosis: repeated respiratory infections.
Treatment: the sample prepared using the embodiment of the present invention 6 is taken orally, sooner or later primary, bfore meals, each 4ml.January For 1 course for the treatment of.
Curative effect: infant starts follow-up always after treatment.After the medication of this infant, three middle of the month catch a cold 2 times, and respiratory tract does not occur Infection.Symptoms are mild, not and hospitalization standard, does not show as runny nose, does not have a fever, and tonsillotome is slightly red and swollen, slightly coughs, and takes orally sense Drug is emitted just to fully recover.9 middle of the month have suffered from afterwards catches a cold twice, and respiratory tract infection does not occur, and also non-hospitalization, shows as runny nose, It does not have a fever, tonsillotome is not red and swollen, slightly coughs, the recovery from illness of oral cold drug.
Embodiment 9
Present embodiment discloses clinical applications of the invention.
Case 3
1. Liu of case, female 5 months 3 years old, go to a doctor May 8 2017 date.
Present illness history: children begin to catch a cold from 1 wheat harvesting period of birth, and cardinal symptom is runny nose, fever, send out later with regard to tonsillotome Inflammation, cough.It monthly catches a cold 1 time, has suffered from Bronchopneumonia within every year old and be hospitalized, to be hospitalized every year 2 times.
Check: ordinary circumstance is fine, and 36.8 DEG C of body temperature, tonsillotome is without enlargement, and pharyngeal no hyperemia, no oedema, cardiopulmonary are normal, For abdomen without tenderness, remaining is normal.
Diagnosis: repeated respiratory infections.
Treatment: the sample prepared using the embodiment of the present invention 5 is taken orally, sooner or later primary, bfore meals, each 1ml.January For 1 course for the treatment of.
Curative effect: infant starts follow-up always after treatment.After the medication of this infant, three middle of the month catch a cold 1 time, and respiratory tract does not occur Infection.Symptoms are mild, and not and hospitalization standard, Symptoms are runny nose, are not had a fever, and tonsillotome is slightly red and swollen, coughs unknown Aobvious, oral cold drug is just fully recovered.Oral drugs are just fully recovered.9 middle of the month have suffered from afterwards catches a cold three times, and respiratory tract infection does not occur. And this catch a cold three times after tonsillotome do not have an enlargement, unobvious, non-hospitalization of coughing, the recovery from illness of oral cold drug.
Embodiment 10
Present embodiments provide the statistical data using present composition treatment infantile respiratory tract infection repeatedly.
The infant for being diagnosed as repeated respiratory infections is randomly divided into test group and negative control group.
Test group is treated using composition of the invention, and treatment method is after throwing off a cold, to take drug one of the present invention The moon is as a treatment course.During the course for the treatment of, if caught a cold again, deactivates drug of the present invention and taken again after throwing off a cold, it is preceding Time of Administration amounts to one month afterwards.
Negative control group is not take any drug after throwing off a cold.
It cures: treating in latter year the infection of the upper respiratory tract 1-2 times, no lower respiratory tract infection.
It is effective: treat the infection of the upper respiratory tract≤3 time in latter year, lower respiratory tract infection 1 time.Symptom mitigates earlier above, continues Time is short, easily cures.
It improves: treating the infection of the upper respiratory tract≤4 time in latter year, lower respiratory tract infection 1-2 times.
Invalid: pretherapy and post-treatment clinical symptoms are unchanged.
2 clinical test results table of table
As seen from the above table, the present invention can effectively treat infantile respiratory tract infection repeatedly.
Above-described embodiment is only one of the preferred embodiment of the present invention, should not be taken to limit protection model of the invention It encloses, as long as that in body design thought of the invention and mentally makes has no the change of essential meaning or polishing, is solved The technical issues of it is still consistent with the present invention, should all be included within protection scope of the present invention.

Claims (10)

1. a kind of composition for infantile respiratory tract infection repeatedly, which is characterized in that by the raw material system including following parts by weight At: 5-50 parts of ginseng, 10-80 parts of Chinese yam, 10-60 parts of endothelium corneum gigeriae galli, 5-60 parts of dried orange peel, 5-30 parts of radix glycyrrhizae preparata, 5-40 parts of the root of purple-flowered peucedanum, bamboo 20-120 parts of drip.
2. a kind of composition for infantile respiratory tract infection repeatedly according to claim 1, which is characterized in that by including The raw material of following parts by weight is made: 8-35 parts of ginseng, 15-65 parts of Chinese yam, and 15-50 parts of endothelium corneum gigeriae galli, 8-45 parts of dried orange peel, radix glycyrrhizae preparata 8- 25 parts, 8-35 parts of the root of purple-flowered peucedanum, 25-105 parts of bamboo juice.
3. a kind of composition for infantile respiratory tract infection repeatedly according to claim 2, which is characterized in that by including The raw material of following parts by weight is made: 10 parts of ginseng, 20 parts of Chinese yam, and 20 parts of endothelium corneum gigeriae galli, 10 parts of dried orange peel, 10 parts of radix glycyrrhizae preparata, the root of purple-flowered peucedanum 10 Part, 30 parts of bamboo juice.
4. a kind of composition for infantile respiratory tract infection repeatedly according to claim 2, which is characterized in that by including The raw material of following parts by weight is made: 30 parts of ginseng, 60 parts of Chinese yam, and 40 parts of endothelium corneum gigeriae galli, 40 parts of dried orange peel, 20 parts of radix glycyrrhizae preparata, the root of purple-flowered peucedanum 30 Part, 100 parts of bamboo juice.
5. a kind of composition for infantile respiratory tract infection repeatedly according to claim 1, which is characterized in that the original The dosage of material meet one of following 3 kinds of situations or more than one:
Ginseng/(dried orange peel+root of purple-flowered peucedanum) is 0.3-0.7;
Radix glycyrrhizae preparata/(Chinese yam+bamboo juice) is 0.1-0.3;
(ginseng+endothelium corneum gigeriae galli)/bamboo juice is 0.48-1.5.
6. a kind of composition for infantile respiratory tract infection repeatedly according to claim 5, which is characterized in that the original The dosage of material meet one of following 3 kinds of situations or more than one:
Ginseng/(dried orange peel+root of purple-flowered peucedanum) is 0.4-0.6;
Radix glycyrrhizae preparata/(Chinese yam+bamboo juice) is 0.12-0.25;
(ginseng+endothelium corneum gigeriae galli)/bamboo juice is 0.6-1.1.
7. a kind of composition for infantile respiratory tract infection repeatedly, feature described in -6 any one according to claim 1 It is, the composition is added pharmaceutically using ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum, bamboo juice as bulk pharmaceutical chemicals Acceptable auxiliary material, the preparation being conventionally prepared.
8. a kind of composition for infantile respiratory tract infection repeatedly according to claim 7, which is characterized in that the system Agent is oral preparation.
9. a kind of preparation method of the composition for infantile respiratory tract infection repeatedly described in -7 any one according to claim 1, Characterized by comprising the following steps:
Step 1: preparation raw material by weight;
Step 2. adds water to cook ginseng, Chinese yam, endothelium corneum gigeriae galli, dried orange peel, radix glycyrrhizae preparata, the root of purple-flowered peucedanum, filtering, and bamboo juice is added in filtrate, mixes Close uniformly after, be concentrated, packing, sterilizing to get.
10. drug, food that composition described in any one of claim 1-9 is used for infantile respiratory tract infection repeatedly in preparation In application.
CN201811249802.0A 2018-10-25 2018-10-25 Composition for treating recurrent respiratory tract infection of children and preparation method and application thereof Active CN109091633B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906456A (en) * 2015-06-30 2015-09-16 孙霞 Traditional Chinese medicine for treating respiratory tract infection of children
CN105617146A (en) * 2016-01-21 2016-06-01 刘建新 Traditional Chinese medicine composition for preventing and treating infantile recurrent respiratory tract infection and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906456A (en) * 2015-06-30 2015-09-16 孙霞 Traditional Chinese medicine for treating respiratory tract infection of children
CN105617146A (en) * 2016-01-21 2016-06-01 刘建新 Traditional Chinese medicine composition for preventing and treating infantile recurrent respiratory tract infection and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
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