CN109011222A - Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method - Google Patents

Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method Download PDF

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Publication number
CN109011222A
CN109011222A CN201811041481.5A CN201811041481A CN109011222A CN 109011222 A CN109011222 A CN 109011222A CN 201811041481 A CN201811041481 A CN 201811041481A CN 109011222 A CN109011222 A CN 109011222A
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CN
China
Prior art keywords
guide plate
body surface
radion
pin hole
close
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Pending
Application number
CN201811041481.5A
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Chinese (zh)
Inventor
陆益栋
路滕新
张瑞萱
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Shanghai Heiyan Medical Technology Co ltd
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Shanghai Heiyan Medical Technology Co ltd
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Priority to CN201811041481.5A priority Critical patent/CN109011222A/en
Publication of CN109011222A publication Critical patent/CN109011222A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103Treatment planning systems
    • A61N5/1031Treatment planning systems using a specific method of dose optimization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103Treatment planning systems
    • A61N5/1039Treatment planning systems using functional images, e.g. PET or MRI
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1012Templates or grids for guiding the introduction of sources

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention provides a body surface positioning guide plate for guiding radioactive particles to treat cancer in a close range. The body surface positioning guide plate comprises a guide plate frame, implanted needle holes and positioning holes/positioning lines, wherein the guide plate frame is fixed on the surface of a human body; the implanted needle holes are distributed in the guide plate frame in groups; the positioning holes/positioning lines are positioned on the fixed point side of the guide plate frame. The guide plate is designed and then manufactured through 3D printing, and is convenient and quick to produce; the guide plate is customized for each patient one to one, and is disposable or used for multiple times, so that the requirements of cleaning, soaking and repeated disinfection in a labor-intensive manner are eliminated, and the risks of biological and chemical dirt residues and cross infection caused by repeated use of different patients are reduced. According to the guide plate, the anastomosis of a preoperative plan and intraoperative implementation is realized, and the needle insertion direction and angle are designed according to the prescription dosage, so that the particle implantation metrological quality control is guaranteed.

Description

Guide the body surface location guide plate and production method of radion close-range treatment cancer
Technical field
The present invention relates to medical tool fields, specially guide the positioning guide plate and system of radion close-range treatment cancer Make method.
Background technique
Seeds implantation technology relies primarily on stereotactic system for the accurate intratumor injection of radioactive particle, Lasting, short-range radioactive ray are issued by mini-radioactive resource, kill tumor tissues to greatest extent, and normal tissue is not Damage or only microlesion.Compared to other oncotherapy technologies, seeds implantation technology technology content itself is simultaneously Not high, difficulty is simultaneously little.It but due to being implanted directly into human body, and is radioactive source, so strictly to hold indication.Doctor at present Seeds implantation is carried out in institute relies primarily on CT to guide surgical experience implantation radiation particle of the doctor according to oneself, There are many uncertainties, such as: to bad controls such as implantation depth, the angles of particle.Therefore, design should in order to solve the above problem Guide plate, the position for tumour of having good positioning in advance, designs inserting needle path, can greatly improve operation accuracy and efficiency.
Summary of the invention
The purpose of the present invention is to provide guidance radion close-range treatment cancer location of operation guide plate, for solve with Upper background technique problem.
In order to achieve the above object, the present invention provides the body surface location guide plate of guidance radion close-range treatment cancer, It include: that guide plate frame, implantation pin hole and location hole/position line, the guide plate frame are fixed on human body surface, the implantation pin hole It is distributed on guide plate frame, the location hole/position line is located at the fixed point side of guide plate frame.
Further, the guide plate frame uses the shape being bonded with human body surface.
Further, the implantation pin hole is the cylindrical conduit of inner hollow.
Further, the respective length of the implantation pin hole is different.
Further, the diameter of the implantation pin hole is different.
Further, the implant needle pore size distribution position and angle difference.
Further, the guide plate frame, implantation pin hole and location hole/position line are 3D printing overall structure.
The production method for guiding the body surface location guide plate of radion close-range treatment cancer, comprising the following steps:
A, doctor according to the image drawing target area of CT scan and jeopardizes organ, obtains original CT data;
B, doctor designs needle track, determines prescribed dose, risk organs dosage according to treatment planning systems, design needle track, really Determine prescribed dose, risk organs dosage;
C, design data is transmitted to guide plate designer by doctor, and CT data are converted into suffering from design software by designer The three-dimensional modeling data of person's human body, according to when different operative site and scanning computed tomography patient body-surface label mark point position, It selects certain body surface range as guide plate profile, which is cut out to thicken processing;
D, designer designs pin hole layout, guide plate thickness, positioning method according to the dose prescription of doctor, builds out 1:1 size Guide plate model;
E, patient is examined to whether there is allergy or other adverse reactions to guide plate making material;
F, three-dimensional guide plate model after the assay was approved, is input to progress surgical guide production in 3D printer.
It is manufactured after being designed the beneficial effects of the invention are as follows the guide plate by 3D printing, convenient for production quick, guide plate is every The one-to-one customization of position patient and disposable or be used for multiple times, eliminates labour-intensive cleaning, impregnates, the need of repeated disinfection It wants, reduces biology and chemical dirt residual and the risk of different patient's Reusability cross-infections.The guide plate realizes art That implements in preceding plan and art coincide, and designs inserting needle orientation angle according to prescribed dose, makes seeds implanted meterological quality control System is protected.
Detailed description of the invention
Fig. 1 is body surface guide plate structure schematic diagram of the invention.
Fig. 2 is implantation pin hole structure schematic diagram of the invention.
Specific embodiment
In order to make implement technical means of the invention, creation characteristic, reach purpose and effect is easy to understand, tie below Conjunction is specifically illustrating, and the present invention is further explained, in the description of the present invention, it should be noted that unless otherwise specific regulation And restriction, term " installation ", " company ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, be also possible to detachable Connection, or be integrally connected to be mechanical connection, it is also possible to be electrically connected;It can be directly connected, intermediate matchmaker can also be passed through Jie is indirectly connected, can connection inside two elements.
Embodiment 1
As shown in Figure 1, the body surface location guide plate of guidance radion close-range treatment cancer, comprising: guide plate frame 1 is planted Enter pin hole 2 and location hole/position line 3, the guide plate frame 1 is fixed on human body surface, and the implantation pin hole 2, which is distributed in, leads On plate framework 1, the location hole/position line 3 is located at the fixed point side of guide plate frame 1.
Further, the guide plate frame 1 is using the shape being bonded with human body surface.
Embodiment 2
As depicted in figs. 1 and 2, the body surface location guide plate of radion close-range treatment cancer is guided, comprising: guide plate frame 1, it is implanted into pin hole 2 and location hole/position line 3, the guide plate frame 1 is fixed on human body surface, the grouping of implantation pin hole 2 distribution In on guide plate frame 1, the location hole/position line 3 is located at the fixed point side of guide plate frame 1.
Further, the guide plate frame 1 is using the shape being bonded with human body surface.
Further, the implantation pin hole 2 is the cylindrical conduit of inner hollow.
Further, the respective length of the implantation pin hole 2 is different.
Further, the diameter of the implantation pin hole 2 is different.
Further, 2 distributing position of implantation pin hole and angle difference.
Further, the guide plate frame 1, implantation pin hole 2 and location hole/position line 3 are 3D printing overall structure.
The production method for guiding the body surface location guide plate of radion close-range treatment cancer, comprising the following steps:
A, doctor according to the image drawing target area of CT scan and jeopardizes organ, obtains original CT data;
B, doctor designs needle track, determines prescribed dose, risk organs dosage according to treatment planning systems, design needle track, really Determine prescribed dose, risk organs dosage;
C, design data is transmitted to guide plate designer by doctor, and CT data are converted into suffering from design software by designer The three-dimensional modeling data of person's human body, according to when different operative site and scanning computed tomography patient body-surface label mark point position, It selects certain body surface range as guide plate profile, which is cut out to thicken processing;
D, designer designs pin hole layout, guide plate thickness, positioning method according to the dose prescription of doctor, builds out 1:1 size Guide plate model;
E, patient is examined to whether there is allergy or other adverse reactions to guide plate making material;
F, three-dimensional guide plate model after the assay was approved, is input to progress surgical guide production in 3D printer.
The operation principle of the present invention is that doctor carries out image scanning using lesion of the CT to patient, ct image and correlation are transmitted For image data to planning system, doctor drawing target outline and jeopardizes organ in the human body CT image of scanning with image processing software, Dosage is calculated in planning system to design particle distribution.Then designer delineates according to doctor target area, the grain calculated The mark point of son distribution and body surface, selects certain body surface range as guide plate profile, which is cut out to thicken place Reason designs guide plate frame 1, position, angle and the length of implantation pin hole 2 is then specifically designed further according to particle distribution, suitably Position, angle and length can accurately guarantee the dosage of medicament and reduce the offset increase puncture of implantation pin hole 2 within the organization Precision;Guide plate is fixed on correct position in use, co-locating by the shape and location hole/position line 3 of guide plate frame 1 by operation It sets.Finally the guide plate of design is printed by 3D printing technique.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.Claimed range of the invention by appended claims and Its equivalent thereof.

Claims (8)

1. guiding the body surface location guide plate of radion close-range treatment cancer, comprising: guide plate frame, implantation pin hole and positioning Hole/position line, it is characterised in that: the guide plate frame is fixed on human body surface, and the implantation pin hole is distributed in guide plate frame On frame, the location hole/position line is located at the fixed point side of guide plate frame.
2. the body surface location guide plate of guidance radion close-range treatment cancer according to claim 1, it is characterised in that: The guide plate frame uses the shape being bonded with human body surface.
3. the body surface location guide plate of guidance radion close-range treatment cancer according to claim 1, it is characterised in that: The implantation pin hole is the cylindrical conduit of inner hollow.
4. the body surface location guide plate of guidance radion close-range treatment cancer according to claim 1, it is characterised in that: The respective length of the implantation pin hole is different.
5. according to the body surface location guide plate of guidance radion close-range treatment cancer described in claim 1, it is characterised in that: institute The diameter for the implantation pin hole stated is different.
6. the body surface location guide plate of guidance radion close-range treatment cancer according to claim 1, it is characterised in that: The implant needle pore size distribution position and angle difference.
7. the body surface location guide plate of guidance radion close-range treatment cancer according to claim 1, it is characterised in that: Guide plate frame, implantation pin hole and the location hole/position line is 3D printing overall structure.
8. a kind of production method of the body surface location guide plate of guidance radion close-range treatment cancer described in claim 1, It is characterized by comprising following steps:
A, doctor according to the image drawing target area of CT scan and jeopardizes organ, obtains original CT data;
B, doctor designs needle track, determines prescribed dose, risk organs dosage, at design needle track, determination according to treatment planning systems Prescription amount, risk organs dosage;
C, design data is transmitted to guide plate designer by doctor, and CT data are converted into patient people by designer in design software The three-dimensional modeling data of body, according to when different operative site and scanning computed tomography patient body-surface label mark point position, selection The shape is cut out as guide plate profile to thicken processing by certain body surface range;
D, designer designs pin hole layout, guide plate thickness, positioning method according to the dose prescription of doctor, builds out leading for 1:1 size Slab;
E, patient is examined to whether there is allergy or other adverse reactions to guide plate making material;
F, three-dimensional guide plate model after the assay was approved, is input to progress surgical guide production in 3D printer.
CN201811041481.5A 2018-09-07 2018-09-07 Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method Pending CN109011222A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811041481.5A CN109011222A (en) 2018-09-07 2018-09-07 Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811041481.5A CN109011222A (en) 2018-09-07 2018-09-07 Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method

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CN109011222A true CN109011222A (en) 2018-12-18

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109499014A (en) * 2018-12-29 2019-03-22 王世广 The production method of dress operation auxiliary device after a kind of gynecological tumor
CN109908494A (en) * 2019-03-25 2019-06-21 天津大学 The minimally invasive radiotherapy three-dimensional surgical guide designing system of close-range particle
CN113244516A (en) * 2021-07-05 2021-08-13 真实维度科技控股(珠海)有限公司 Non-coplanar puncture template manufacturing method based on bony multipoint positioning and template

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105664380A (en) * 2016-03-04 2016-06-15 湖北嘉一三维高科股份有限公司 Radiotherapy guide plate of intracranial tumors
CN105963002A (en) * 2016-08-01 2016-09-28 北京启麟科技有限公司 Three-dimensional printed minimally invasive guide template and making method thereof
CN206324839U (en) * 2016-10-21 2017-07-14 北京启麟科技有限公司 A kind of 3D printing guide plate for Minimally Invasive Surgery
CN108245789A (en) * 2018-03-28 2018-07-06 北京启麟科技有限公司 The transplanting guider of cervical carcinoma close-range treatment Minimally Invasive Surgery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105664380A (en) * 2016-03-04 2016-06-15 湖北嘉一三维高科股份有限公司 Radiotherapy guide plate of intracranial tumors
CN105963002A (en) * 2016-08-01 2016-09-28 北京启麟科技有限公司 Three-dimensional printed minimally invasive guide template and making method thereof
CN206324839U (en) * 2016-10-21 2017-07-14 北京启麟科技有限公司 A kind of 3D printing guide plate for Minimally Invasive Surgery
CN108245789A (en) * 2018-03-28 2018-07-06 北京启麟科技有限公司 The transplanting guider of cervical carcinoma close-range treatment Minimally Invasive Surgery

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109499014A (en) * 2018-12-29 2019-03-22 王世广 The production method of dress operation auxiliary device after a kind of gynecological tumor
CN109499014B (en) * 2018-12-29 2021-03-23 王世广 Method for manufacturing gynecological tumor after-loading operation auxiliary device
CN109908494A (en) * 2019-03-25 2019-06-21 天津大学 The minimally invasive radiotherapy three-dimensional surgical guide designing system of close-range particle
CN113244516A (en) * 2021-07-05 2021-08-13 真实维度科技控股(珠海)有限公司 Non-coplanar puncture template manufacturing method based on bony multipoint positioning and template
CN113244516B (en) * 2021-07-05 2021-10-08 真实维度科技控股(珠海)有限公司 Non-coplanar puncture template manufacturing method based on bony multipoint positioning and template

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Application publication date: 20181218