CN108922589A - A kind of radiotherapy planning display system and storage medium - Google Patents

A kind of radiotherapy planning display system and storage medium Download PDF

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Publication number
CN108922589A
CN108922589A CN201810691565.7A CN201810691565A CN108922589A CN 108922589 A CN108922589 A CN 108922589A CN 201810691565 A CN201810691565 A CN 201810691565A CN 108922589 A CN108922589 A CN 108922589A
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image
radiotherapy planning
time point
control point
point data
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CN108922589B (en
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荣成城
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Shanghai United Imaging Healthcare Co Ltd
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    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture

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Abstract

The embodiment of the invention discloses a kind of radiotherapy planning display system and storage mediums.The system includes:Data acquisition facility is used to obtain the original radiotherapy planning of the raw video sequence of distribution and the second Annual distribution at the first time and executes control point data;Fusing device is used to execute control point data according to raw video sequence and original radiotherapy planning, determines target image sequence and target dose distribution series, and merge target image sequence and target dose distribution series, obtains plan display image sequence;Display device is for showing plan display image sequence.Through the above technical solution, it realizes and is performed before in radiotherapy planning, by the target dose distribution series of the corresponding plan radiotherapy of the various time points of radiotherapy planning, it is presented in the image sequence at corresponding time point, each intermediate plan link information of radiotherapy planning is shown in a manner of more intuitive, more accurate and detailed, is supported to adjust radiotherapy planning for treating physician and provide strong data.

Description

A kind of radiotherapy planning display system and storage medium
Technical field
The present embodiments relate to medical image processing technology more particularly to a kind of radiotherapy planning display systems and storage to be situated between Matter.
Background technique
Radiotherapy (abbreviation radiotherapy) is a kind of effective treatment method for illnesss such as tumour and cancers, usually to trouble Before person carries out radiotherapy, treating physician can formulate the radiotherapy planning for being suitable for patient, and substantially process is:Obtain patient's lesion device The 3-dimensional image of the corresponding physical feeling of official, and the formulation based on above-mentioned 3-dimensional image progress radiotherapy planning.
In order to be performed before the therapeutic effect for understanding prepared radiotherapy planning in radiotherapy planning, it will usually in radiotherapy meter In the system of drawing, the corresponding intergal dose distribution of entire radiotherapy planning is shown in the 3-dimensional image or four-dimensional image of patient.But It is the display mode of existing radiotherapy planning, treating physician can only be made to recognize the final therapeutic effect of entire radiotherapy planning, and It can not recognize the more detailed treatment condition of radiotherapy planning.
Summary of the invention
The embodiment of the present invention provides a kind of radiotherapy planning display system and storage medium, to realize more intuitively and in detail The therapeutic effect for showing radiotherapy planning, to provide more accurate and detailed radiotherapy planning information for treating physician.
In a first aspect, the embodiment of the invention provides a kind of radiotherapy planning display systems, including:
Data acquisition facility is put for obtaining the raw video sequence of distribution and the original of the second Annual distribution at the first time The plan for the treatment of executes control point data, and the raw video sequence and the original radiotherapy planning execution control point data correspond to same One object;
Fusing device, for executing control point data according to the raw video sequence and the original radiotherapy planning, really Set the goal image sequence and target dose distribution series, and merges the target image sequence and target dose distribution series, obtains It must plan to show image sequence;
Display device, for showing that the plan shows image sequence.
Second aspect, the embodiment of the invention also provides a kind of storage medium comprising computer executable instructions, the meters Calculation machine executable instruction by computer processor when being executed for performing the following operations:
It obtains the original radiotherapy planning of the raw video sequence of distribution and the second Annual distribution at the first time and executes control point Data, the raw video sequence and the original radiotherapy planning execute control point data and correspond to the same object;
Control point data is executed according to the raw video sequence and the original radiotherapy planning, determines target image sequence With target dose distribution series, and the target image sequence and target dose distribution series are merged, obtains plan display image Sequence;
Show that the plan shows image sequence.
The embodiment of the present invention obtains the same object at any time by the data acquisition facility in radiotherapy planning display system Between the raw video sequence being distributed and the original radiotherapy planning being distributed at any time execute control point data;Fusing device is according to described in Raw video sequence and the original radiotherapy planning execute control point data, determine target image sequence and target dose distribution sequence Column, and the target image sequence and target dose distribution series are merged, obtain plan display image sequence;Display device is shown The plan shows image sequence.It realizes and is performed before in radiotherapy planning, the various time points of radiotherapy planning are corresponding The target dose distribution series for planning radiotherapy, are presented in the image sequence at corresponding time point, with more intuitive, more accurate and Detailed mode shows each intermediate plan link information of radiotherapy planning, is provided with to adjust radiotherapy planning for treating physician The data of power are supported.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of one of embodiment of the present invention one radiotherapy planning display system;
Fig. 2 is the structural schematic diagram of one of embodiment of the present invention two radiotherapy planning display system.
Specific embodiment
The present invention is described in further detail with reference to the accompanying drawings and examples.It is understood that this place is retouched The specific embodiment stated is used only for explaining the present invention rather than limiting the invention.It also should be noted that in order to just Only the parts related to the present invention are shown in description, attached drawing rather than entire infrastructure.
Radiotherapy planning display system provided by the embodiment of the present invention is suitable for having formulated radiotherapy planning for patient, but not yet Before executing the radiotherapy planning, predictability radiotherapy result corresponding to each intermediate link in radiotherapy planning is shown, especially It is suitable for thorax abdomen lesions to treat scene.It will be illustrated by taking thorax abdomen lesion as an example in the embodiment of the present invention.
For there is the patient of thorax abdomen lesion, swept carrying out computerized tomography (Computed Tomography, CT) to it Retouch or nuclear magnetic resonance (Nuclear magnetic resonance, MR) scan during, due to the respiratory movement meeting of patient Cause internal each histoorgan, tumour spatial position variation, therefore the CT images of the thorax abdomen obtained or MR image can not Reflect the actual position of all histoorgans and tumour etc. in therapeutic process.So, it is formulated based on the CT images or MR image Radiotherapy planning may be deviated, be unfavorable for subsequent radiotherapy.Therefore in the embodiment of the present invention, before obtaining radiotherapy (i.e. raw video sequence is according to several tactic trouble of time point to a series of patient image's data in certain period of time Person's image, because it is with temporal information, therefore alternatively referred to as four-dimensional image), which is able to reflect out is exhaled by patient Inhale organ caused by movement and knub position variation.Later, according to various time points, by the intermediate ring of the radiotherapy planning of formulation The predictive radiotherapy result (such as dosage is distributed, alternatively referred to as plan radiotherapy result) of section is shown in corresponding sufferer image.This Sample, treating physician just can more intuitively observe real-time change process of the radiotherapy planning of formulation in simulation therapeutic process, More accurate radiotherapy planning is formulated for it, and data support is provided.
Embodiment one
Fig. 1 is a kind of structural schematic diagram of radiotherapy planning display system provided in this embodiment, present embodiments provides one Kind radiotherapy planning display system 100, the radiotherapy planning display system 100 include:The data acquisition communicated to connect each other Device 110, fusing device 120 and display device 130, wherein data acquisition facility 110, for obtaining distribution at the first time The original radiotherapy planning of raw video sequence and the second Annual distribution executes control point data, raw video sequence and original radiotherapy Plan executes control point data and corresponds to the same object;Fusing device 120, for what is obtained according to data acquisition facility 110 Raw video sequence and original radiotherapy planning execute control point data, determine target image sequence and target dose distribution series, And target image sequence and target dose distribution series are merged, obtain plan display image sequence;Display device 130, for showing Show that the plan that fusing device obtains shows image sequence.
Wherein, communication connection mode can be is connected by conducting wire, is also possible to connect by bus, which can wrap One of a few class bus structures or a variety of are included, for example including data/address bus, control bus, expansion bus or are used a variety of total The local bus of any bus structures in cable architecture.For example, these architectures include but is not limited to industrial standard body Architecture (ISA) bus, microchannel architecture (MAC) bus, enhanced isa bus, Video Electronics Standards Association (VESA) Local bus and peripheral component interconnection (PCI) bus.Distribution refers to the various time points in raw video sequence at the first time Distribution.Second Annual distribution refers to that original radiotherapy planning executes the distribution of various time points in control point data.At the first time Time point in distribution and the second Annual distribution may be the same or different.
Radiotherapy planning executes control point data and refers to the control data for executing radiotherapy planning for controlling radiotherapy apparatus, such as It can be the shape that the rotation angle of radiotherapy apparatus treatment head, the shape (multi-leaf optical grating shape) that multi-leaf optical grating is formed, tungsten door are formed Shape (tungsten door shape), the radiation data such as hop count and dose rate.Original radiotherapy planning executes control point data and refers to radiotherapy meter It draws the radiotherapy planning that timing obtains and executes control point data.Illustratively, data acquisition facility 110 includes original control point number According to module is obtained, it is used for:According to the corresponding plan image of object, the default control point data of radiotherapy planning is determined;According to default Point data is controlled, PATH GENERATION is based on, original radiotherapy planning is obtained and executes control point data.Wherein, object refers to radiotherapy The radiation object of plan, i.e. sufferer or patient.Plan image refers to the patient image for formulating radiotherapy planning, such as CT images or MR image, can be 3-dimensional image, be also possible to four-dimensional image.Default control point data refers to the radiotherapy planning tentatively formulated The control point data of middle setting.PATH GENERATION is alternatively referred to as control point transfer algorithm or motion fitting algorithm, is to pre- If control point data carries out the fitting based on constraint, to obtain the calculation of smooth treatment head motion profile Control point data Method.That is, original control point data acquisition module obtains preparatory when formulating radiotherapy planning first according to the plan image of patient The default control point data of setting, and be that basic data generate original with PATH GENERATION with the default control point data Radiotherapy planning executes control point data, and to obtain, accuracy is higher, the biggish control point data of data-intensive degree.For example, default Control point data is respectively the radiation control data that treatment head rotation angle is 10 °, 25 °, 40 ° and 60 °, and by the default control Point data obtains multiple control point datas of the more crypto set at 1 ° of angle interval of rotation, multiple controls at 1 ° of the rotation angle interval Point data processed is just that original radiotherapy planning executes control point data.
Target image sequence refers to that the image sequence for carrying out mixing operation, each image therein both correspond to merge Operation corresponding time point (i.e. time of fusion point).Target dose distribution series refer to the dosage for carrying out mixing operation point Cloth sequence, each dosage distribution therein both correspond to the point of time of fusion corresponding to mixing operation.Each time of fusion point Dosage distribution needs to execute control point data according to the radiotherapy planning of plan image and corresponding time of fusion point to determine.Plan is aobvious Show that image refers to the image for showing the radiotherapy planning result of some time of fusion point.Plan display image sequence refer to according to Multiple plans of multiple time of fusion point arrangements show image.Above-mentioned time of fusion point is the trigger timing that radiotherapy planning is shown, A certain time of fusion point is reached, just shows the corresponding radiotherapy planning of time of fusion point.Therefore time of fusion point is target image Sequence and target radiotherapy planning execute the time identifier of control point data acquisition.Time of fusion point can be according to first time minute Temporal information in cloth and the second Annual distribution determines, such as can be time grain in distribution at the first time and the second Annual distribution The various time points in smaller Annual distribution are spent, is also possible to raw video sequence and original radiotherapy planning executes control points Various time points in, in the corresponding Annual distribution of the higher data of data precision;Time of fusion point be also possible to user according to The multiple time points set according to self-demand, for example, user according to it should be understood that radiotherapy planning intermediate link information it is true Determine various time points.
Specifically, the radiotherapy planning display system as provided by the embodiment of the present invention is for the therapeutic effect to plan More intuitive interim displaying is carried out, so first passing through data acquisition when above-mentioned radiotherapy planning display system 100 is run Device 110 gets the required basic data that generation plan shows image sequence, can be used to carrying planned treatment outcome (i.e. agent Amount distribution) raw video sequence, and can be used for determine plan radiotherapy result original radiotherapy planning execute control point data. Raw video sequence can be to be carried out the radioscanning of certain period of time to patient and obtains in advance, and original radiotherapy planning executes control Point data processed can be the plan image according to patient and the radiotherapy planning formulated obtains.Get required basic data it Afterwards, raw video sequence and original radiotherapy planning are executed control point data and are transmitted to fusing device by data acquisition facility 110 120.Fusing device 120 executes control point data according to the raw video sequence received and original radiotherapy planning, determine by Control point data is executed according to the mutual corresponding target image sequence of various time points and target radiotherapy planning, then by target radiotherapy meter The plan image for drawing execution control point data and patient determines corresponding target dose distribution series.Later, by target image Sequence and target dose distribution series are merged according to corresponding time point, and acquisition can carry out the plan that radiotherapy planning is shown It shows image sequence, and the plan is shown that image sequence is transmitted to display device 130.Display device 130 is intended to display shadow As sequence requires to be shown according to display.It should be noted that display format here can be two dimension or three-dimensional display Form.If it is two-dimentional display format, then fusion process is exactly the mesh that target dose distribution is blended in two dimension slicing form It marks in image.If it is Three-dimensional Display form, then fusion process is exactly by each of target image sequence two dimension slicing Image is merged with two dimension slicing dosage distribution corresponding in target dose distribution, obtains multiple two-dimentional fusion results;And according to Three-dimensional fusion result is obtained by three-dimensional reconstruction according to multiple two-dimentional fusion results, and shows the three-dimensional fusion result.
Illustratively, fusing device 120 includes:Time of fusion point determining module 121, for determining the present fusion time Point;Target image determining module 122, for what is determined according to raw video sequence, determining and time of fusion point determining module 121 Present fusion time point corresponding current goal image;Target dose is distributed determining module 123, for according to original radiotherapy planning Execute control point data, determining current goal corresponding with the determining present fusion time point of time of fusion point determining module 121 Dosage distribution;Fusion Module 124, the current goal image and target dose determined for merging target image determining module 122 It is distributed the current goal dosage distribution that determining module 123 determines, obtains and currently melts with what time of fusion point determining module 121 determined It closes time point corresponding current planning and shows image;Loop module 125 is used for after obtaining current planning and showing image, will Next time of fusion point is updated to present fusion time point, and triggers target image determining module 122 and target dose distribution The execution of determining module 123, until present fusion time point is the last one time of fusion point.
Wherein, present fusion time point refers to the time of fusion point for carrying out plan display video generation processing.Currently Target image is patient image corresponding with present fusion time point, can be the shadow directly obtained from raw video sequence Picture, be also possible to pre-process at least one image in raw video sequence or the setting processings such as interpolation after obtain Image.The distribution of current goal dosage is dosage distribution corresponding with present fusion time point, can be single time point Dosage distribution, the integral dose distribution at multiple time points before being also possible to present fusion time point.Current planning shows shadow It seem that plan corresponding with present fusion time point shows image.
120 acquisition plan of fusing device shows that the process of image sequence is operated according to single time of fusion dot cycle. When it is implemented, time of fusion point determining module 121 selects a time of fusion point from multiple time of fusion points, as fusion The start time point of operation, which is present fusion time point, later by the current time of fusion Point is sent to target image determining module 122 and target dose distribution determining module 123.122 basis of target image determining module The present fusion time point of acquisition obtains current goal image from raw video sequence, and current goal image is sent to Fusion Module 124.Target dose is distributed determining module 123 then according to the present fusion time point of acquisition, first from original radiotherapy meter It draws to execute and is determined in control point data and execute control point data by present fusion time point corresponding radiotherapy planning (i.e. current goal is put The plan for the treatment of executes control point data).Later, when executing control point data according to current goal radiotherapy planning and formulate radiotherapy planning Based on present fusion time point corresponding plan image, determine that current goal dosage is distributed, and by current goal dosage Distribution is sent to Fusion Module 124.Fusion Module 124 then merges the current goal image received and current goal dosage point The distribution of current goal dosage is superimposed on current goal image by cloth, is obtained current planning and is shown image, and triggers cyclic module The execution of block 125.Loop module 125 is then from multiple time of fusion points, by next fusion after present fusion time point Time point is determined as new present fusion time point, and triggers target image determining module 122 and the determining mould of target dose distribution The execution of block 123 and its subsequent module.The circulation triggering of modules is carried out as procedure described above and is executed, until present fusion Time point is the last one time of fusion point, and subsequent modules are finished, and acquired multiple current plannings are aobvious at this time Show that image is arranged according to multiple time of fusion points, is plan display image sequence.It can more automatically obtain and put in this way The each intermediate plan link information for treating plan, improves the application convenience of radiotherapy planning display system.
The technical solution of the present embodiment obtains the same object by the data acquisition facility in radiotherapy planning display system The raw video sequence being distributed at any time and the original radiotherapy planning being distributed at any time execute control point data;Fusing device according to Control point data is executed according to raw video sequence and original radiotherapy planning, determines target image sequence and target dose distribution sequence Column, and target image sequence and target dose distribution series are merged, obtain plan display image sequence;Display device display plan Show image sequence.It realizes and is performed before in radiotherapy planning, by the corresponding plan radiotherapy of the various time points of radiotherapy planning Target dose distribution series, be presented in the image sequence at corresponding time point, with more intuitive, more accurate and detailed side Formula shows each intermediate plan link information of radiotherapy planning, so that adjusting radiotherapy planning for treating physician provides strong data It supports.
Embodiment two
Fig. 2 is a kind of structural schematic diagram of radiotherapy planning display system provided in this embodiment, and the present embodiment is with above-mentioned reality Based on applying example one, the explanation of same as the previously described embodiments or corresponding device and term repeats no more in the present embodiment.
Referring to fig. 2, on the basis of the above embodiment 1, target image determining module 122 includes in the present embodiment:First Time point query unit 1221 whether there is present fusion time point for inquiring in first time distribution;First image obtains Unit 1222 is taken, in raw video sequence and current there are obtaining when present fusion time point in first time distribution The corresponding image of time of fusion point, as current goal image;Second image capturing unit 1223, for being distributed in first time In when present fusion time point is not present, according to present fusion time point and raw video sequence, interpolation obtains current goal shadow Picture.
Specifically, when obtaining current goal image, first triggering executes first time point and looks into target image determining module 122 Unit 1221 is ask, to determine in the corresponding first time distribution of raw video sequence with the presence or absence of present fusion time point.Such as Fruit first time point query unit 1221 determines that there are present fusion time points in distribution at the first time, then illustrating raw video There are current goal image in sequence, it can directly trigger and execute the first image capturing unit 1222, it will be in raw video sequence Present fusion time point, corresponding image data was determined as current goal image.If first time point query unit 1221 determines Present fusion time point is not present in distribution at the first time, then illustrate that current goal image is not present in raw video sequence, Triggering is needed to execute the second image capturing unit 1223, then to carry out image according to present fusion time point and raw video sequence Interpolation obtains current goal image.
Illustratively, the second image capturing unit 1223 is specifically used for:From raw video sequence, obtains currently melt respectively Corresponding first image of first time point before closing time point and the second time point after present fusion time point are corresponding Second image;According to the first image and the second image, image feature variation tendency is determined;Using image feature variation tendency as shadow As interpolation constrains, and according to first time point, present fusion time point and the second time point, to the first image and the second image into Row interpolation obtains current goal image.
Wherein, first time point and the second time point refer respectively to most connect in distribution at the first time with present fusion time point Time of fusion point before and after close.First image refers to image corresponding with first time point in raw video sequence. Second image refers to image corresponding with the second time point in raw video sequence.Image feature variation tendency refers to two width images Between, in the variation tendency of the same image feature, such as two chest CT images, since patient respiratory moves, cause two Tumour in image after the variation of part organ site or radiotherapy in image becomes smaller than the tumour in image before radiotherapy, on Rheme sets change direction or tumour becomes smaller, and trend is image feature variation tendency.
Specifically, the second image capturing unit 1223 carries out interpolation to the image in raw video sequence to obtain current mesh When marking image, two images, the process needed for first obtaining interpolation is needed to be:First determine at the first time distribution in present fusion Former and later two immediate time of fusion points of time point --- first time point and the second time point, later in raw video sequence It is middle to get first time point and the second time point corresponding first image and the second image respectively.
Later, the second image capturing unit 1223 is according to first time point, present fusion time point, the second time point, One image and the second image carry out interpolation to the first image and the second image, obtain current goal image.I.e. using at the first time Point, present fusion time point and the second time point determine numerical interpolation ratio when image interpolation, and utilize the Interpolation Proportions Interpolation is carried out to the first image and the second image, obtains current goal image.Image can be opened using front and back two in this way to be worked as The acquisition of preceding target image improves the precision of current goal image.The process is specially:Second image capturing unit, 1223 basis First image and the second image capturing are to the image feature variation tendency between two images.Later, with image feature variation Interpolation constraint condition of the trend as subsequent images interpolation, utilizes first time point, present fusion time point and the second time point Determining Interpolation Proportions carry out restrictive interpolation to the first image and the second image, obtain current goal image.It can obtain in this way More accurate interpolation result is obtained, so that the patient image of carrying plan radiotherapy result is more accurate, further increases radiotherapy meter Draw the precision of display.
Based on the above technical solution, the target dose distribution determining module 123 in the present embodiment includes:Target control Point data determination unit 1231 processed, for executing control point data, determining and present fusion time point according to original radiotherapy planning Corresponding current goal radiotherapy planning executes control point data;Target dose is distributed determination unit 1232, for putting according to target The plan for the treatment of executes control point data and plan image, determines that current goal dosage is distributed.
Specifically, target dose distribution determining module 123 first triggers performance objective when determining the distribution of current goal dosage Control point data determination unit 1231 obtains current goal radiotherapy planning to execute control point data according to original radiotherapy planning Execute control point data.This is because dosage distribution is being calculated by radiotherapy planning execution control point data and plan image , if there is no present fusion time point in the second Annual distribution, need to execute original radiotherapy planning control point data Interpolation is carried out, current goal radiotherapy planning is obtained and executes control point data.Performance objective dosage distribution determination unit is triggered again 1232, control point data and plan image are executed by current goal radiotherapy planning to calculate the distribution of current goal dosage, such energy Enough obtain more accurate dosage distribution results.
Illustratively, target control point data determination unit 1231 includes:Second time point inquired subelement, for the Inquiry whether there is present fusion time point in two Annual distributions;First control point data acquisition subelement, at second Between in distribution there are when present fusion time point, obtain original radiotherapy planning execute in control point data with present fusion time point Corresponding radiotherapy planning executes control point data, executes control point data as current goal radiotherapy planning;Second control points According to obtaining subelement, when for present fusion time point to be not present in the second Annual distribution, according to present fusion time point and Original radiotherapy planning executes control point data, and interpolation obtains current goal radiotherapy planning and executes control point data.
Specifically, target control point data determination unit 1231 is obtaining current goal radiotherapy planning execution control point data When, first triggering executed for the second time point and inquires subelement, to determine that original radiotherapy planning executes control point data corresponding the It whether there is present fusion time point in two Annual distributions.If the second time point inquiry subelement determines in the second Annual distribution There are present fusion time points, then illustrating that there are current goal radiotherapy plannings to hold in original radiotherapy planning execution control point data Row control point data, can directly trigger and execute the first control point data acquisition subelement, original radiotherapy planning is executed control Present fusion time point, corresponding radiotherapy planning execution control point data was determined as the execution of current goal radiotherapy planning in point data Control point data.If the second time point inquiry subelement, which determines, is not present present fusion time point in the second Annual distribution, that Illustrate that original radiotherapy planning executes in control point data there is no current goal radiotherapy planning execution control point data, then needs to touch Hair executes the second control point data acquisition subelement, to execute control point according to present fusion time point and original radiotherapy planning Data carry out the interpolation that radiotherapy planning executes control point data, obtain current goal radiotherapy planning and execute control point data.
Further, the second control point data acquisition subelement is specifically used for:Control points are executed from original radiotherapy planning In, third time point corresponding first radiotherapy planning before obtaining present fusion time point respectively execute control point data and The 4th time point corresponding second radiotherapy planning after present fusion time point executes control point data;According to the third time Point, present fusion time point and the 4th time point execute control point data to the first radiotherapy planning and the second radiotherapy planning execute It controls point data and carries out interpolation, obtain current goal radiotherapy planning and execute control point data.
Wherein, third time point and the 4th time point refer respectively to most connect in the second Annual distribution with present fusion time point Time of fusion point before and after close.
Specifically, the second control point data acquisition subelement executes control point data to radiotherapy planning and carries out interpolation to obtain When current goal radiotherapy planning executes control point data, first determine immediate with present fusion time point in the second Annual distribution Former and later two time of fusion points --- third time point and the 4th time point executes control point data in original radiotherapy planning later It is middle to get third time point and the 4th time point corresponding first radiotherapy planning execution control point data and the second radiotherapy respectively Plan executes control point data.Later, then third time point, present fusion time point and the 4th time point are utilized, determines to put The plan for the treatment of executes the numerical interpolation ratio when data interpolating of control point, and is held using the numerical interpolation ratio to the first radiotherapy planning Row control point data and the second radiotherapy planning execute control point data and carry out interpolation, obtain current goal radiotherapy planning and execute control Point data.Current goal radiotherapy planning can be carried out using former and later two control point datas in this way execute obtaining for control point data It takes, improves current goal radiotherapy planning and execute the precision of control point data, to further increase the precision of dosage distribution, in turn Further increase the precision that radiotherapy planning is shown.
Illustratively, target dose distribution determination unit 1232 is specifically used for:When planning image is four-dimensional plan image, Plan corresponding with present fusion time point in control point data and four-dimensional plan image is executed according to current goal radiotherapy planning Image determines that current goal dosage is distributed.
Specifically, as before, determining for dosage distribution is needed to plan image as the reference image calculated.If planning shadow Seem 3-dimensional image, then no matter current goal radiotherapy planning execute control point data corresponding present fusion time point whether with The time point of 3-dimensional image is corresponding, is all referring to image with the 3-dimensional image.And when planning image is four-dimensional image, currently The calculating of target dose distribution, it is necessary to be determined from four-dimensional image and be closer to the three of time point for present fusion time point Image is tieed up, then take the 3-dimensional image as the calculating of reference image progress dosage distribution.More accurate dosage can be obtained in this way Distribution.
Further, target dose distribution determination unit 1232 is specifically used for:According to plan image and current goal radiotherapy Treatment head rotation angle, multi-leaf optical grating shape, tungsten door shape, treatment bed position, radiation jump in plan execution control point data Several and dose rate determines that current goal dosage is distributed.Specifically, it is executed using plan image and current goal radiotherapy planning The determination process that point data carries out the distribution of current goal dosage is controlled, is that control is executed with current goal radiotherapy planning in more detail Treatment head rotation angle, multi-leaf optical grating shape, tungsten door shape, treatment bed position, radiation hop count and radiological agent in point data processed The case where dose rate is radiation simulated conditions, and simulation ray irradiation extremely plans image, to obtain the distribution of current goal dosage.
Illustratively, target dose distribution determination unit 1232 is specifically used for:If current goal dosage is distributed as currently melting The intergal dose distribution for closing time point corresponding plan radiation, then execute control according to plan image and current goal radiotherapy planning Treatment head rotation angle, multi-leaf optical grating shape, tungsten door shape, treatment bed position, radiation hop count and radiological dose in point data Rate determines the present dose distribution of present fusion time point corresponding plan radiation;It is distributed according to present dose, and currently melts At least one historical dose distribution for closing at least one corresponding plan radiation of history time of fusion point before time point, determines Intergal dose distribution, is distributed as current goal dosage.
Wherein, history time of fusion point is the time of fusion point before being arranged in present fusion time point time point.History Dosage distribution is dosage distribution corresponding with present dose distribution, and present dose distribution is corresponding dose of present fusion time point Amount distribution, and historical dose distribution is then the corresponding dosage distribution of history time of fusion point.Intergal dose distribution is then multiple lists The accumulation result of time point corresponding dosage distribution.
Specifically, in radiotherapy planning, for a time of fusion point, its corresponding radiotherapy planning executes control points According to the radioactive ray of plan radiation can be precomputed in the intracorporal radiological agent of sufferer by executing control point data according to the radiotherapy planning It measures intensity distribution (distribution of abbreviation dosage).That is, each time of fusion point in radiotherapy planning has its corresponding plan The dosage of radiation is distributed.For present fusion time point, target dose is distributed determination unit 1232 according to current goal radiotherapy meter Draw treatment head rotation angle, multi-leaf optical grating shape, tungsten door shape, the treatment bed position, linear accelerating executed in control point data The radiation hop count and dose rate of device calculate present dose distribution.Similarly, target dose is distributed determination unit 1232 It is the historical dose distribution being calculated one by one by the above process.Later, when present dose distribution being merged with multiple history Between to put corresponding multiple historical doses distribution cumulative, obtain the accumulation agent of corresponding plan radiation of current pre-confluent time point Amount distribution.The predictive treatment results that accurate radiotherapy planning can be obtained in this way, can further increase radiotherapy planning The accuracy of display.
The technical solution of the present embodiment, by the way that the first time of fusion point query unit is arranged in target image determining module Inquiry whether there is present fusion time point in first time distribution;First image capturing unit is deposited in first time distribution At present fusion time point, present fusion time point corresponding image in raw video sequence is obtained, as current goal shadow Picture;And second image capturing unit when present fusion time point is not present in first time distribution, when according to present fusion Between point and raw video sequence, interpolation obtain current goal image.More accurate current goal image can be obtained, raising is put The precision of current goal image during the plan for the treatment of is shown.By being distributed in determining module in target dose, target control point is set Data determination unit executes control point data according to original radiotherapy planning, determines current goal corresponding with present fusion time point Radiotherapy planning executes control point data;Target dose is distributed determination unit and executes control point data and meter according to target radiotherapy planning Image is drawn, determines that current goal dosage is distributed.More accurate current goal dosage distribution can be obtained, to further increase The accuracy that interim radiotherapy planning is shown.
The embodiment of storage medium provided in an embodiment of the present invention below, the operation of method performed by the storage medium with Operation performed by radiotherapy planning display system belongs to the same inventive concept in the various embodiments described above, in the implementation of storage medium The detail content of not detailed description in example can refer to the embodiment of above-mentioned radiotherapy planning display system.
Embodiment three
The present embodiment provides a kind of storage mediums comprising computer executable instructions, and computer executable instructions are by counting For executing a kind of radiotherapy planning display methods when calculation machine processor executes, this method includes:
It obtains the original radiotherapy planning of the raw video sequence of distribution and the second Annual distribution at the first time and executes control point Data, raw video sequence and original radiotherapy planning execute control point data and correspond to the same object;
Control point data is executed according to raw video sequence and original radiotherapy planning, determines target image sequence and target agent Distribution series are measured, and merge target image sequence and target dose distribution series, obtain plan display image sequence;
Display plan display image sequence.
Optionally, control point data is executed according to raw video sequence and original radiotherapy planning, determines target image sequence With target dose distribution series, and target image sequence and target dose distribution series are merged, obtains plan display image sequence Including:
Determine present fusion time point;
According to raw video sequence, current goal image corresponding with present fusion time point is determined;
Control point data is executed according to original radiotherapy planning, determines current goal dosage corresponding with present fusion time point Distribution;
Current goal image and the distribution of current goal dosage are merged, current planning corresponding with present fusion time point is obtained Show image;
Next time of fusion point is updated to present fusion time point, and returns to execution according to raw video sequence, really The step of fixed current goal image corresponding with present fusion time point, until when present fusion time point is the last one fusion Between point.
Optionally, according to raw video sequence, determine that current goal image corresponding with present fusion time point includes:
Inquiry whether there is present fusion time point in first time distribution;
If so, image corresponding with present fusion time point in raw video sequence is obtained, as current goal image;
If it is not, then according to present fusion time point and raw video sequence, interpolation obtains current goal image.
Further, according to present fusion time point and raw video sequence, interpolation obtains current goal image and includes:
From raw video sequence, corresponding first image of first time point before present fusion time point is obtained respectively The second image corresponding with the second time point after present fusion time point;
According to the first image and the second image, image feature variation tendency is determined;
Using image feature variation tendency as image interpolation constrain, and according to first time point, present fusion time point and Second time point carried out interpolation to the first image and the second image, and obtained current goal image.
Optionally, control point data is executed according to original radiotherapy planning, determined corresponding with present fusion time point current Target dose is distributed:
Control point data is executed according to original radiotherapy planning, determines current goal radiotherapy corresponding with present fusion time point Plan executes control point data;
Control point data and plan image are executed according to target radiotherapy planning, determines that current goal dosage is distributed.
Wherein, control point data is executed according to original radiotherapy planning, determines current mesh corresponding with present fusion time point Mark radiotherapy planning executes control point data:
Inquiry whether there is present fusion time point in the second Annual distribution;
If so, obtaining original radiotherapy planning executes radiotherapy planning corresponding with present fusion time point in control point data Control point data is executed, executes control point data as current goal radiotherapy planning;
If it is not, then executing control point data according to present fusion time point and original radiotherapy planning, interpolation obtains current mesh It marks radiotherapy planning and executes control point data.
Further, control point data is executed according to present fusion time point and original radiotherapy planning, interpolation obtains current Target radiotherapy planning executes control point data:
It is executed in control point data from original radiotherapy planning, obtains the third time point before present fusion time point respectively Corresponding first radiotherapy planning executes control point data and the 4th time point corresponding second after present fusion time point puts The plan for the treatment of executes control point data;
According to third time point, present fusion time point and the 4th time point, control points are executed to the first radiotherapy planning Interpolation is carried out according to control point data is executed with the second radiotherapy planning, current goal radiotherapy planning is obtained and executes control point data.
Optionally, control point data and plan image are executed according to target radiotherapy planning, determines that current goal dosage is distributed Including:
When planning image is four-dimensional plan image, control point data and four-dimensional meter are executed according to current goal radiotherapy planning Plan image corresponding with present fusion time point in image is drawn, determines that current goal dosage is distributed.
Optionally, control point data and plan image are executed according to target radiotherapy planning, determines that current goal dosage is distributed Including:
The treatment head in control point data, which is executed, according to plan image and current goal radiotherapy planning rotates angle, leafy light Grid shape, tungsten door shape, treatment bed position, radiation hop count and dose rate, determine that current goal dosage is distributed.
Optionally, when current goal dosage is distributed as the intergal dose distribution of present fusion time point corresponding plan radiation When, control point data and plan image are executed according to target radiotherapy planning, determines that the distribution of current goal dosage includes:
The treatment head in control point data, which is executed, according to plan image and current goal radiotherapy planning rotates angle, leafy light Grid shape, tungsten door shape, treatment bed position, radiation hop count and dose rate, determine the corresponding plan of present fusion time point The present dose of radiation is distributed;
At least one history time of fusion point according to present dose distribution and before present fusion time point is corresponding At least one historical dose of plan radiation is distributed, and is determined that intergal dose is distributed, is distributed as current goal dosage.
The computer storage medium of the embodiment of the present invention, can be using any of one or more computer-readable media Combination.Computer-readable medium can be computer-readable signal media or computer readable storage medium.It is computer-readable Storage medium for example may be-but not limited to-the system of electricity, magnetic, optical, electromagnetic, infrared ray or semiconductor, device or Device, or any above combination.The more specific example (non exhaustive list) of computer readable storage medium includes:Tool There are electrical connection, the portable computer diskette, hard disk, random access memory (RAM), read-only memory of one or more conducting wires (ROM), erasable programmable read only memory (EPROM or flash memory), optical fiber, portable compact disc read-only memory (CD- ROM), light storage device, magnetic memory device or above-mentioned any appropriate combination.In this document, computer-readable storage Medium can be any tangible medium for including or store program, which can be commanded execution system, device or device Using or it is in connection.
Computer-readable signal media may include in a base band or as carrier wave a part propagate data-signal, Wherein carry computer-readable program code.The data-signal of this propagation can take various forms, including but unlimited In electromagnetic signal, optical signal or above-mentioned any appropriate combination.Computer-readable signal media can also be that computer can Any computer-readable medium other than storage medium is read, which can send, propagates or transmit and be used for By the use of instruction execution system, device or device or program in connection.
The program code for including on computer-readable medium can transmit with any suitable medium, including --- but it is unlimited In wireless, electric wire, optical cable, RF etc. or above-mentioned any appropriate combination.
The computer for executing operation of the present invention can be write with one or more programming languages or combinations thereof Program code, described program design language include object oriented program language-such as Java, Smalltalk, C++, It further include conventional procedural programming language-such as " C " language or similar programming language.Program code can be with It fully executes, partly execute on the user computer on the user computer, being executed as an independent software package, portion Divide and partially executes or executed on a remote computer or server completely on the remote computer on the user computer.? Be related in the situation of remote computer, remote computer can pass through the network of any kind --- including local area network (LAN) or Wide area network (WAN)-be connected to subscriber computer, or, it may be connected to outer computer (such as mentioned using Internet service It is connected for quotient by internet).
Note that the above is only a better embodiment of the present invention and the applied technical principle.It will be appreciated by those skilled in the art that The invention is not limited to the specific embodiments described herein, be able to carry out for a person skilled in the art it is various it is apparent variation, It readjusts and substitutes without departing from protection scope of the present invention.Therefore, although being carried out by above embodiments to the present invention It is described in further detail, but the present invention is not limited to the above embodiments only, without departing from the inventive concept, also It may include more other equivalent embodiments, and the scope of the invention is determined by the scope of the appended claims.

Claims (11)

1. a kind of radiotherapy planning display system, which is characterized in that including:
Data acquisition facility, by obtaining based on the raw video sequence of distribution at the first time and the original radiotherapy of the second Annual distribution Execution control point data is drawn, the raw video sequence and the original radiotherapy planning execution control point data correspond to same Object;
Fusing device determines mesh for executing control point data according to the raw video sequence and the original radiotherapy planning Image sequence and target dose distribution series are marked, and merge the target image sequence and target dose distribution series, are counted Draw display image sequence;
Display device, for showing that the plan shows image sequence.
2. system according to claim 1, which is characterized in that the fusing device includes:
Time of fusion point determining module, for determining present fusion time point;
Target image determining module, for according to the raw video sequence, determination to be corresponding with the present fusion time point Current goal image;
Target dose is distributed determining module, and for executing control point data according to the original radiotherapy planning, determination is worked as with described The corresponding current goal dosage distribution of preceding time of fusion point;
Fusion Module, for merging the current goal image and current goal dosage distribution, acquisition is currently melted with described It closes time point corresponding current planning and shows image;
Loop module, for after obtaining the current planning and showing image, next time of fusion point to be updated to currently Time of fusion point, and the execution of the target image determining module and target dose distribution determining module is triggered, until working as Preceding time of fusion point is the last one time of fusion point.
3. system according to claim 2, which is characterized in that the target image determining module includes:
First time point query unit whether there is the present fusion time for inquiring in first time distribution Point;
First image capturing unit, for, there are when the present fusion time point, obtaining institute in first time distribution Image corresponding with the present fusion time point in raw video sequence is stated, as the current goal image;
Second image capturing unit, when for the present fusion time point to be not present in first time distribution, foundation The present fusion time point and the raw video sequence, interpolation obtain the current goal image.
4. system according to claim 3, which is characterized in that the second image capturing unit is specifically used for:
From the raw video sequence, the first time point corresponding first before the present fusion time point is obtained respectively Image and the second time point corresponding second image after the present fusion time point;
According to first image and second image, image feature variation tendency is determined;
It is constrained the image feature variation tendency as image interpolation, and according to the first time point, the present fusion Time point and second time point carry out interpolation to first image and second image, obtain the current goal Image.
5. system according to claim 2, which is characterized in that the target dose is distributed determining module and includes:
Target control point data determination unit, for executing control point data according to the original radiotherapy planning, it is determining with it is described Present fusion time point corresponding current goal radiotherapy planning executes control point data;
Target dose is distributed determination unit, for executing control point data and plan shadow according to the current goal radiotherapy planning Picture determines that current goal dosage is distributed.
6. system according to claim 5, which is characterized in that the target control point data determination unit includes:
Second time point inquired subelement, whether there is the present fusion time for inquiring in second Annual distribution Point;
First control point data acquisition subelement, for there are the present fusion time points in second Annual distribution When, it obtains the original radiotherapy planning and executes radiotherapy planning execution corresponding with the present fusion time point in control point data Point data is controlled, executes control point data as the current goal radiotherapy planning;
Second control point data acquisition subelement, for the present fusion time point to be not present in second Annual distribution When, control point data is executed according to the present fusion time point and the original radiotherapy planning, interpolation obtains the current mesh It marks radiotherapy planning and executes control point data.
7. system according to claim 6, which is characterized in that the second control point data acquisition subelement is specifically used In:
It is executed in control point data from the original radiotherapy planning, when obtaining the third before the present fusion time point respectively Between put that corresponding first radiotherapy planning executes control point data and the 4th time point after the present fusion time point is corresponding The second radiotherapy planning execute control point data;
According to the third time point, the present fusion time point and the 4th time point, to first radiotherapy planning It executes control point data and second radiotherapy planning executes control point data and carries out interpolation, obtain the current goal radiotherapy meter It draws and executes control point data.
8. system according to claim 5, which is characterized in that the target dose distribution determination unit is specifically used for:
When the plan image is four-dimensional plan image, control point data and institute are executed according to the current goal radiotherapy planning Plan image corresponding with the present fusion time point in four-dimensional plan image is stated, determines the current goal dosage distribution.
9. the system according to claim 5 or 8, which is characterized in that the target dose distribution determination unit is specifically used for:
The treatment head rotation angle, more in control point data is executed according to the plan image and the current goal radiotherapy planning Leaf raster shape, tungsten door shape, treatment bed position, radiation hop count and dose rate determine the current goal dosage distribution.
10. system according to claim 9, which is characterized in that the target dose distribution determination unit is specifically used for:
If the current goal dosage is distributed as the intergal dose distribution of the present fusion time point corresponding plan radiation, The treatment head in control point data, which is executed, according to the plan image and the current goal radiotherapy planning rotates angle, leafy light Grid shape, tungsten door shape, treatment bed position, radiation hop count and dose rate, determine that the present fusion time point is corresponding The present dose of plan radiation is distributed;
According to present dose distribution and at least one history time of fusion point pair before the present fusion time point At least one historical dose for the plan radiation answered is distributed, and the intergal dose distribution is determined, as the current goal dosage Distribution.
11. a kind of storage medium comprising computer executable instructions, which is characterized in that the computer executable instructions by For performing the following operations when computer processor executes:
It obtains the original radiotherapy planning of the raw video sequence of distribution and the second Annual distribution at the first time and executes control point data, The raw video sequence and the original radiotherapy planning execute control point data and correspond to the same object;
Control point data is executed according to the raw video sequence and the original radiotherapy planning, determines target image sequence and mesh Dosage distribution series are marked, and merge the target image sequence and target dose distribution series, obtain plan display image sequence;
Show that the plan shows image sequence.
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