CN107480416A - A kind of radiotherapy treatment planning system - Google Patents

A kind of radiotherapy treatment planning system Download PDF

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Publication number
CN107480416A
CN107480416A CN201610405616.6A CN201610405616A CN107480416A CN 107480416 A CN107480416 A CN 107480416A CN 201610405616 A CN201610405616 A CN 201610405616A CN 107480416 A CN107480416 A CN 107480416A
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plan
unit
module
data
treatment planning
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Inventor
周付根
吴大可
姚进
刘博�
徐轩昂
郭斌
梁斌
李永宝
李超
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Rui Dima Medical Science And Technology Co Ltd
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Rui Dima Medical Science And Technology Co Ltd
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Abstract

The application belongs to field of medical device, specifically, the present invention discloses a kind of radiotherapy treatment planning system, including:Case management module, treatment planning systems primary module and local data storage module, case management module obtains Patient list from data server, the image data of given patient is downloaded and is stored in local data storage module, treatment planning systems primary module obtains patient image's data from local data storage module, and combine the design of the carry out treatment plan of advance parameter, obtain radiotherapy treatment planning scheme, radiotherapy treatment planning scheme is stored in local data storage module in the form of a file, data are intended to by case management module and send the Database Systems into data server to be managed.The present invention is stored by the image data to patient and treatment plan data, removes the acquisition for repeating patient image's data and the formulation for the treatment of plan from, and then shortens treatment and Diagnostic Time, so as to reduce treatment cost.

Description

A kind of radiotherapy treatment planning system
Technical field
The invention belongs to field of medical device, and more specifically, the present invention relates to a kind of radiotherapy treatment planning system.
Background technology
Radiotherapy is one of important means for carrying out oncotherapy, is had for improving human health and gain human longevity Very great meaning.The statistics that the World Health Organization (WHO) provides shows, in it can cure cancer, cure rate of performing the operation For 22%, the cure rate that radiotherapy combines with operation is 6%, and radiotherapy cure rate 12%, chemotherapy is only 5%.It can be seen that radiotherapy is The important technical that cancer is cured.Radiotherapy be based on radiating physics, radioecology, clinical radiotherapy, With reference to knowledge such as Clinical Oncology, surgery, clinical practice, iconographies, using the means of radiation cure disease, it is mainly used to control Treat malignant tumour.
In recent years, there occurs great variety for radiation therapy technology.With the development of radiation therapy technology, radiotherapy towards The target of " accurate radiotherapy " is advanced, and intelligent radiation therapy technology the sixth of the twelve Earthly Branches turns into one of advanced and effective means of radiotherapy.I.e. Precise Diagnosis will be carried out, be accurately positioned, accurately plan and accurate treatment by asking in radiation therapy process, to improve single dose Realize for the purpose of accurately treating, it is ensured that reduce complication while Partial controll rate is provided.Over the course for the treatment of, it is necessary to obtain trouble The image data of person, and joined according to these image datas and therapy apparatus set in advance (accelerator) physical parameter, collimater Number, robot motion's parameter formulate the treatment plan of patient.
But lack the technical scheme stored to the image data and treatment plan data of patient in the prior art, When patient needs successive treatment, it is necessary to carry out the acquisition of patient image's data and the formulation for the treatment of plan again, therefore, lead Cause the therapeutic process Diagnostic Time of patient comparatively laborious, and treatment time is longer, and then add treatment cost.
The content of the invention
In view of this, the invention provides a kind of radiotherapy treatment planning system, by the image data to patient and control Treat planning data to be stored, realize in tumor radiotherapy therapeutic process, remove from repeat the acquisitions of patient image's data with And the formulation for the treatment of plan, and then shorten treatment and Diagnostic Time, so as to reduce treatment cost.
To achieve the above object, the present invention provides following technical scheme:
A kind of radiotherapy treatment planning system, including:Case management module, treatment planning systems primary module and local data are deposited Module is stored up, wherein,
The case management module, for entering row data communication with data server, patient image's data are obtained, will be specified The image data of patient is downloaded and is stored in the local data storage module, and provides user interface, by accessing The treatment-related statistical information of database displaying in data server is stated, patient image's data include main image sequence With secondary image sequence;
The treatment planning systems primary module, for obtaining patient image's number from the local data storage module According to, and the patient image's data and parameter preset that are provided according to the case management module carry out setting for treatment plan Meter, designs radiotherapy treatment planning scheme, the parameter preset includes:Collimater parameter, robot motion's parameter and treatment The physical parameter of machine;
The local data storage module, for storing patient image's data and the radiotherapy treatment planning side The radiotherapy treatment planning scheme is stored in the local data in the form of a file and deposited by case, the radiotherapy treatment planning scheme Module is stored up, is intended to data by the case management module and sends to the Database Systems in the data server carry out pipe Reason.
Wherein, the case management module, for DICOM RT to be imported or exported by DICOM RT radiotherapies webmaster Data.
Preferably, the case management module includes:Inquire about, browse with statistic unit, data loading and uploading unit with And data interface unit, wherein,
The inquiry, browse and statistic unit, for by accessing the Database Systems, obtaining and showing the patient List;
Data load and uploading unit, for patient image's data, the statistical information to be loaded and uploaded Related data;
Data interface unit, for carrying out data transmission respectively with the treatment planning systems primary module.
Preferably, the treatment planning systems primary module includes:User log-in block, image registration and Fusion Module, wheel Wide editor module, plan design module, QA quality assurance plannings design module, plan comparison module, plan demonstration module, plan Fusion Module and systematic parameter configuration module, wherein,
The user log-in block, for verifying the legitimacy of login user and the initialization of user right;The figure As registration and Fusion Module, for the registration between different modalities image and generation fused images;
The profile editor module, for carrying out the extraction and reconstruction of therapy area and sensitive organization's profile, establish patient Virtual three-dimensional tissue model;
The plan design module, for being designed and optimizing to radiotherapy treatment planning;
The QA plans design module, the QA for providing patient care plan plan design function;
The plan comparison module, for carrying out the comparison between different plans, obtain optimized treatment plan;
The plan demonstration module, for simulating the therapeutic process of Patient treatment plan, and demonstrated;
The plan Fusion Module, for being overlapped to the dosage field of different plans;
The systematic parameter configuration module, for configuring the configuration parameter for the treatment of planning systems.
Preferably, described image registration includes with Fusion Module:Image registration subelement, registering assessment unit and image melt Unit is closed, wherein,
Described image registration subelement, for registration, area-of-interest registration, image rigid registration and figure to be marked As deformable registration;
The registering assessment unit, the accuracy and essence of registration are assessed for providing a variety of image display mechanisms auxiliary users Degree;
Described image integrated unit, the organizational information for two groups of image sequences to be included are merged into same image sequence In.
Preferably, the profile editor module includes:VOI ATLs administrative unit, contour line delineate unit, profile by hand The area of computer aided extraction unit and profile operational unit of line, wherein,
The VOI ATLs administrative unit, for every attribute of the user configuration VOI, create self-defined template, institute Stating every attribute includes:Transparency when title, type, color and display;
The contour line delineates unit by hand, and editor is delineated by hand for being provided for the user;
The area of computer aided extraction unit of the contour line, for carrying out contour line automatically or semi-automatically to the patient Information extraction;
The profile operational unit, the profile collection for being formed to the contour line are operated and edited.
Preferably, the plan design module includes:Plan initialization unit, plan hand-designed unit, plan inversely Design cell, Rapid Dose Calculation unit, Program Assessment unit and adaptive planning unit, wherein,
The plan initialization unit, carried out for being initialized to the parameter preset, and to the parameter preset Verification;
The plan hand-designed unit, concentrates from launched field for user and chooses launched field node and direction, and carry out hand Work elements addition launched field;
The plan reverse-engineers unit, for being positioned to the launched field node and direction and the radiotherapy Plans are adjusted;
The Rapid Dose Calculation unit, the radiological dose of radiotherapy treatment planning is calculated for providing a variety of dose calculation methodologies ;
The Program Assessment unit, for assessing the radiotherapy treatment planning scheme, and assess the radiological agent Measure field;
The adaptive planning unit, user is aided in the radiotherapy treatment planning for providing a variety of Plan rescheduling instruments Scheme is improved.
Preferably, the plan initialization unit includes:Parameter initialization unit and Verification unit are treated, wherein,
The treatment parameter initialization unit, for being initialized to the treatment parameter of the radiotherapy treatment planning scheme Set;
The Verification unit, for the treatment parameter of the radiotherapy treatment planning scheme to be verified and veritified.
Preferably, the plan reverse-engineers unit and included:Optimization aim design cell and Plan rescheduling unit, wherein,
The optimization aim design cell, controlled for providing a variety of optimization aim designs for user's progress radiation Treat the determination of plans;
The Plan rescheduling unit, for being held to treatment time, launched field quantity, number of nodes, launched field fine setting and launched field Row order carries out Plan rescheduling.
Preferably, the dose calculation module, the radiation for the treatment of plan is calculated for providing a variety of dose calculation methodologies Dosage field.
Understand that compared with prior art, the invention discloses a kind of radiotherapy treatment planning system via above-mentioned technical scheme System, including:Case management module, treatment planning systems primary module and local data storage module, the case management module from Patient list is obtained in data server, the image data of given patient is downloaded and is stored in the local datastore mould Block, the treatment planning systems primary module obtains patient image's data from the local data storage module, and combines The design of the carry out treatment plan of advance parameter, obtains radiotherapy treatment planning scheme, in the form of a file by the radiotherapy Plans are stored in the local data storage module, and being intended to data by the case management module sends to data, services Database Systems in device are managed.The present invention is stored by the image data to patient and treatment plan data, Remove the acquisition for repeating patient image's data and the formulation for the treatment of plan from, and then shorten treatment and Diagnostic Time, so as to Reduce treatment cost.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing There is the required accompanying drawing used in technology description to be briefly described, it should be apparent that, drawings in the following description are only this The embodiment of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can also basis The accompanying drawing of offer obtains other accompanying drawings.
Fig. 1 is a kind of general structure schematic diagram of radiotherapy treatment planning system provided by the invention;
Fig. 2 is the structural representation of the case management module provided by the invention;
Fig. 3 is the structural representation of the treatment planning systems main program provided by the invention;
Fig. 4 is the structural representation of described image provided by the invention registration and Fusion Module.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other under the premise of creative work is not made Embodiment, belong to the scope of protection of the invention.
The invention discloses a kind of radiotherapy treatment planning system, referring specifically to accompanying drawing 1, is put for one kind provided by the invention The general structure schematic diagram for the treatment of planning systems is penetrated, specifically, the radiotherapy treatment planning system includes:Case management module 101, Treatment planning systems primary module 102 and local data storage module 103, wherein,
The case management module 101, for entering row data communication with data server, patient image's data are obtained, will The image data of given patient is downloaded and is stored in the local data storage module, and provides user interface, passes through visit The treatment-related statistical information of database displaying in the data server is asked, patient image's data include main image Sequence and secondary image sequence;
The treatment planning systems primary module 102, for obtaining the patient from the local data storage module 101 Image data, and the patient image's data and parameter preset that are provided according to the case management module 101 are treated The design of plan, designs radiotherapy treatment planning scheme, and the parameter preset includes:Collimater parameter, robot motion's parameter And the physical parameter of therapy apparatus;
The local data storage module 103, for storing patient image's data and the radiotherapy treatment planning The radiotherapy treatment planning scheme is stored in the local data by scheme, the radiotherapy treatment planning scheme in the form of a file Memory module 103, data are intended to by the case management module 101 and sent to the Database Systems in the data server It is managed.
The case management module, for DICOM RT data to be imported or exported by DICOM RT radiotherapies webmaster.
As shown in figure 1, case management module 101 be responsible for and PERCOM peripheral communication, and treatment planning systems primary module 102 using by Patient image's data that case manager obtains carry out the design for the treatment of plan.With the patient's shadow obtained by case manager As data carry out the design for the treatment of plan.Case management module provides the overall user interface for the treatment of planning systems, passes through The treatment-related statistical information of database displaying is accessed, and it is specific to receive other function sub-modules completion of the operation calls of user Work.In the entire system, only the module interacts with data server.Case manager is responsible for from data server It is middle to obtain current Patient list, the image data of given patient is downloaded and is stored in local data storage module.Treatment Planning system primary module combines the collimater parameter being pre-configured with, robot motion's ginseng using local patient image's data The physical parameter (being automatically configured by systematic parameter configuration module when treatment planning systems start) of number and therapy apparatus, is controlled Treat the design of plan.After the design for completing treatment plan, planning data will be stored in local datastore mould in the form of a file In block, it is responsible for being intended to data sending to patient database system by case manager and is managed.
The invention discloses a kind of radiotherapy treatment planning system, including:Case management module, treatment planning systems primary module And local data storage module, the case management module obtain Patient list from data server, by the shadow of given patient As data are downloaded and are stored in the local data storage module, the treatment planning systems primary module is deposited from the local data Patient image's data are obtained in storage module, and combine the design of the carry out treatment plan of advance parameter, obtain radiotherapy Plans, the radiotherapy treatment planning scheme is stored in the local data storage module in the form of a file, by described Case management module is intended to the Database Systems that data are sent into data server and is managed.The present invention is by patient Image data and treatment plan data stored, remove the acquisition for repeating patient image's data and treatment plan from Formulation, and then shorten treatment and Diagnostic Time, so as to reduce treatment cost.
Refer to the structural representation that accompanying drawing 2 is the case management module provided by the invention, the specific case Management module 101 includes:Inquire about, browse and statistic unit 201, data loading and uploading unit 202 and data interface unit 203, wherein,
The inquiry, browse with statistic unit 201, it is described for by accessing the Database Systems, obtaining and showing Patient list;
Data load and uploading unit 202, for being loaded to patient image's data, the statistical information and Pass related data;
Data interface unit 203, for carrying out data transmission respectively with the treatment planning systems primary module.
The function of above-mentioned case management module includes:
1. patient browses, inquires about and statistical function, by accessing patient database system, obtain and show current patient List, which includes the essential information of the patient statistical information related to plan.Patient query's function is provided, can be according to spy Determine field and carry out the inquiry of case and the statistical analysis of Query Result.
2. loading and the upload function of patient data, case management module is unique in/out of radiotherapy treatment planning system Mouthful.In the entire system, only the module is handed over system database (including treatment data storehouse and DICOM gateway datas storehouse) Mutually.User operates the data preserved during other functional modules and will be buffered in local disk;User is only waited to complete to operate and return When returning to case management module, just case data are analyzed by case management module is unified, update database and on Pass case data.
, it is necessary to load the different images sequence of the patient when user opens the patient specified, including main image sequence and Secondary image sequence.Wherein, main image sequence must be CT images.Loading for PET images, can be with loading procedure Selection calculates SUV using SUV methods to the PET images to be changed, and can change the parameter of existing parameter or addition missing.
Because the treatment spatial dimension of SRT is bigger, have one for the image data used in the works Provisioning request, such as CT scan scope are not less than 20cm, and thickness is no more than 1.5mm, no spacing equal thickness scanning.
3.DICOM RT interface functions, case management module provide the interface function of DICOM RT objects.Pass through parsing Local DICOM RT data, planning system can import the image, profile and dose data of patient, for plan comparison and melt Close.Input and output of image data etc. after the input and output of enabled DICOM RT objects, registration and fusion.
Preferably, the case manager of the case management module can be imported or exported by DICOM RT webmasters DICOM RT data, and the treatment planning systems primary module can read the dependency number in the local data storage module at any time According to.
In addition, user can import DICOM RT data directly in case manager.Equally, case manager meeting The image data (may include ROI data) of patient is stored in local data storage module.Treatment planning systems primary module The data in local data storage module, and the design planned can be read at any time.Data are finally intended to via case Management program is sent to patient database system, or by case management module through DICOM (RT) gateways with DICOM RT shape Formula exports.
Accompanying drawing 3 is referred to, is the structural representation of the treatment planning systems primary module provided by the invention, it is described above Treatment planning systems primary module 102 mainly includes:User log-in block 301, image registration and Fusion Module 302, profile editor Module 303, plan design module 304, QA (QUALITY ASSURANCE, quality assurance) plan designs module 305, plan ratio Compared with module 306, plan demonstration module 307, plan Fusion Module 308 and systematic parameter configuration module 309, wherein,
The user log-in block 301, it is described for verifying the legitimacy of login user and the initialization of user right User includes:Keeper, technical staff, physics teacher, doctor, start-up and treatment technician.
The function that above-mentioned user log-in block provides includes:The legitimate verification that user logs in, it is legal when user logs in Property checking primarily to preventing illegal operation from being destroyed to software systems and patient data;The initialization of user right, Yong Huquan The initialization of limit, define service condition of the different user for planning system difference in functionality.The system is according to radiotherapy Control and data flow, operation user intend being divided into six groups:Technical staff, administrator, physics teacher, doctor, trainer Member and treatment technician.And for each group, administrator can be separately provided the manipulable mould of each user Block.
Described image registration and Fusion Module 302, for the registration between different modalities image and generation fusion figure Picture.
In treatment planning systems, image registration is used for Fusion Module by matching the spatial relationship of different images sequence Realize the fusion display auxiliary target area of different modalities image and the profile of tissue of interest delineate, the deformation of dosage field it is cumulative come it is real Existing four-dimensional dose field computation and plan are merged.
Accompanying drawing 4 is referred to, is the structural representation of described image provided by the invention registration and Fusion Module, it is described above Image registration includes with Fusion Module 302:Image registration subelement 401, registering assessment unit 402 and image fusion unit 403, Wherein,
Described image registration subelement 401, for be marked registration, area-of-interest registration, image rigid registration with And image deformation registration.
Image registration problem is by being modeled as the iterative process of optimization problem, it is necessary to according to image subject to registration The suitable space transform models of feature selection describe the motion organized between image and suitable similarity criterion describes image Between spatial match degree, optimal spatial alternation is progressively found using optimization method to maximize or minimize similitude Criterion, so as to realize the matching between image.Wherein, space transform models, similarity criterion and optimizing search method are images Three fundamentals of registration.
According to the difference of space transform models, image registration module provides rigid registration method and deformable registration method two Kind.Rigid registration method only solves the D translation and rotation relationship between two groups of images, and its registration result is 4 × 4 conversion squares Battle array.The similarity criterion that rigid registration method can use has:Mark position deviation, gradation of image mean square deviation, image mutual trust Breath.Wherein, mark position deviation needs user to choose one group of three-dimensional feature point respectively in two groups of images subject to registration, registration Method is by minimizing the distance between character pair point come solution room transformation parameter.
Deformable registration method solves the position offset of same anatomic tissue o'clock image space in two groups of images, can retouch State displacement and the deformation of patient tissue.Its registration result is one group of three consistent with registering reference image sequence spatial relationship Wei Xingbianxiangliangchang (Deformation Field), anatomic tissue o'clock is have recorded at each voxel location of Deformation Field and is imaged in two groups of images The three-dimensional position offset of position.The similarity criterion that deformable registration method can use has:Gradation of image difference mean square deviation with And image mutual information.
The registering assessment unit 402, the accuracy of registration is assessed for providing a variety of image display mechanisms auxiliary users And precision.
Registration assesses submodule and provides accuracy and precision that a variety of image display mechanisms auxiliary users assess registration, bag Include:Image co-registration display mechanism, image divide window display mechanism etc..In addition, this module also allows user in three directions to figure Improve rigid registration result as carrying out manual translation and rotation.
Described image integrated unit 403, the organizational information for two groups of image sequences to be included are merged into same image sequence In row.
The organizational information that two groups of image sequences include is merged into same image sequence by image co-registration submodule, is being taken turns Exterior feature is delineated etc. and can preferably aid in user to carry out plan design.This module provides man-machine interactively weighted average fusion function With the automatic fusion function based on wavelet transformation.
The profile editor module 303, for carrying out the extraction and reconstruction of therapy area and sensitive organization's profile, establish and suffer from The virtual three-dimensional tissue model of person.
Profile editor module is used to delineate the area-of-interests (VOI) such as skin, target area tissue and vitals, these regions It will be used to optimize dosage distribution.Each VOI is made up of many profile collection, and each profile collection is divided into solid outline collection and hollow profile Collection.Each profile collection includes the contour line on different faultage images.Contour line is one-to-one with faultage image, that is, is existed Only allow to delineate a contour line on each faultage image.Will inside VOI the complicated geometry of definien, can create more Individual profile collection.Such as to create an annular VOI (annular target area, for example to remove at prostate the part of urethra, or Supraoesophageal annular tumour etc.), can create that a solid outer shroud profile is several to be used as outer shroud first, then create one it is hollow For profile collection as inner ring, the VOI being made up of the two profile collection will be rendered as an annular.
The profile editor module includes:VOI ATLs administrative unit, contour line delineate the meter of unit, contour line by hand Calculation machine assisted extraction unit and profile operational unit, wherein,
The VOI ATLs administrative unit, for every attribute of the user configuration VOI, create self-defined template, institute Stating every attribute includes:Transparency when title, type, color and display.
User can freely configure VOI every attribute, including transparency when VOI title, type, color, display Deng, and it is stored as customized VOI templates.In the VOI of newly-built plan, directly can directly be created from VOI ATLs. For different therapentic parts, different VOI templates are called.
The contour line delineates unit by hand, delineates editor by hand for being provided for the user, it supports point-by-point by hand Line is delineated, continuously delineated by hand;Support delineating and wiping for circular paintbrush;When the contour line that user delineates is not in adjacent tomography When, the contour line in intermediate layer can be obtained by way of interpolation, and be shown in phantom, and user can select to receive interpolation knot Fruit, it can also be modified on the basis of interpolation result.
The area of computer aided extraction unit of the contour line, for carrying out contour line automatically or semi-automatically to the patient Information extraction;
The profile operational unit, the profile collection for being formed to the contour line are operated and edited.
The plan design module 304, for being designed and optimizing to radiotherapy treatment planning.
Plan design module provides the Inverse Planning design function based on launched field weight optimization.During planned design, root first Concentrated according to geometry optimization principle from be possible to launched field and choose one group of launched field subset, then pass through each launched field in majorized subset Weight meets design object that user specifies (including dosage distribution objectives, the total hop count of irradiation etc.).
The plan design module includes:Plan initialization unit, plan hand-designed unit, plan reverse engineer list Member, Rapid Dose Calculation unit, Program Assessment unit and adaptive planning unit, wherein,
The plan initialization unit, carried out for being initialized to the parameter preset, and to the parameter preset Verification;
The plan hand-designed unit, concentrates from launched field for user and chooses launched field node and direction, and carry out hand Work elements addition launched field;
The plan reverse-engineers unit, for being positioned to the launched field node and direction and the radiotherapy Plans are adjusted;
The Rapid Dose Calculation unit, the radiological dose of radiotherapy treatment planning is calculated for providing a variety of dose calculation methodologies ;
The Program Assessment unit, for assessing the radiotherapy treatment planning scheme, and assess the radiological agent Measure field;
The adaptive planning unit, user is aided in the radiotherapy treatment planning for providing a variety of Plan rescheduling instruments Scheme is improved.
Plan initialization unit described above includes:Parameter initialization unit and Verification unit are treated, wherein, it is described Parameter initialization unit is treated, for carrying out Initialize installation to the treatment parameter of the radiotherapy treatment planning scheme;The ginseng Number authentication unit, for the treatment parameter of the radiotherapy treatment planning scheme to be verified and veritified.
The plan, which reverse-engineers unit, to be included:Optimization aim design cell and Plan rescheduling unit, wherein, the optimization Target design unit, the radiotherapy treatment planning scheme is carried out really for user for providing a variety of optimization aim designs It is fixed;
The Plan rescheduling unit, for being held to treatment time, launched field quantity, number of nodes, launched field fine setting and launched field Row order carries out Plan rescheduling.
The dose calculation module is used to provide a variety of dose calculation methodologies to calculate the radiological dose field for the treatment of plan.
The QA plans design module 305, the QA for providing patient care plan plans design function, to ensure patient care plan Treatment treatment guarantee.
QA plan design modules provide the instrument for creating QA plans.By creating QA plans, a patient can be treated meter Draw and overlap onto in die body CT images series, then the latter is exported to die body, and to output dose compared with intended dose, from And verify the dosage output situation for the treatment of plan.
Creating QA plans needs by two groups of plans created.One group be patient actual therapeutic plan;Another group is Utilize the die body plan of die body data creation.By the geometric center of the tissue of interest that matches patient care plan and die body plan or The picture centre of person's CT data, the launched field data of patient are copied to after spatial alternation in die body treatment space and obtain QA meters Draw.
Finally give QA in the works, the related parameter of launched field comes from the treatment plan of patient, including launched field path set, penetrates Wild parameter.
Other plan parameters come from and die body plan, including contour line for the treatment of method for tracing, tissue of interest etc..Carry out During Rapid Dose Calculation, calculated using the CT data of die body.
The plan comparison module 306, for carrying out the comparison between different plans, obtain optimized treatment plan.
For the different plans under the same course for the treatment of, it is necessary to according to waiting dosage field and DVH to be compared, for selecting most Good treatment plan.Plan comparison module supports the comparison of multiple plans, and comparing content includes isodose, isodose surface, DVH Image and dosage statistical value.Plan comparison module provides abundant dosage display mode and pattern, allows user clearly Distinguish different plans.
The plan demonstration module 307, for simulating the therapeutic process of Patient treatment plan, makes user intuitively evaluate and test firmly Part controls and collision situation.
Plan the virtual implementation process of demonstration module displaying treatment plan, and demonstrated, verify hardware in therapeutic process Collaborative Control situation of collision relation, robot treatment head and C-arm etc..If including four-dimensional image data in the works, demonstration Module can show target area tracking effect according to the patient respiratory movable information of four-dimensional image.
The plan Fusion Module 308, for being overlapped to the dosage field of different plans.
In clinical practice, that patient has born certain radiological dose before radiotherapy is received be present.Than As patient relapse and metastasis focus may occur again after receiving the radiotherapy of other forms in the recent period or receiving radiotherapy; It could also be possible that in therapeutic process because special circumstances need interruption treatment to reformulate treatment plan.Now, it is accurately to comment The radiation for estimating histoorgan (the especially sensitive organ such as spinal cord) is measured, and it is effectively protected, it is necessary to controlled in design Patient's exposure dose is considered when treating plan.
The purpose of plan Fusion Module is exactly to solve the dosage superposition problem between radiotherapy treatment planning.By that will radiate Dosage field is uniformly arrived under the space coordinates of current planning consensus sequence by coordinate transform, makes doctor can be with planned design The post dose of new and old plan superposition is assessed, so as to design more reasonably treatment plan.
The systematic parameter configuration module 309, for configuring the configuration parameter for the treatment of planning systems.
The function that systematic parameter configuration module includes has:Display parameters configuration, plan parameters configuration and quick plan template Configuration.The configuration of display parameters includes:Isodose indicating template adds and modification, the addition of VOI templates and modification, CT/MR/ The color matching of each interactive tool in color mapping table and software interface that PET images acquiescence uses.The configuration bag of plan parameters Include:For different method for tracing, configure the time of patient and the interval time of imaging, whether enabled automatically save function And the time interval automatically saved, the electron density model of configuration/modification piecewise linearity are set.Quick plan template configuration bag Include:Definition template title, configuration need the color of the isodose and dosage line shown, the VOI for planning to need to use, enabled It is automatic to delineate function, plan gradation, therapentic part, treatment path, method for tracing, optimization method, collimater used and prescription agent Amount.In addition, according to different optimization methods, it is also necessary to the criterion of configuration optimization.To adjust strong sequential optimization plan based on weight Exemplified by, it is necessary to configure target area, vitals, shell VOI and total MU Optimality Criteria.
The invention discloses a kind of radiotherapy treatment planning system, including:Case management module, treatment planning systems primary module And local data storage module, the case management module obtain Patient list from data server, by the shadow of given patient As data are downloaded and are stored in the local data storage module, the treatment planning systems primary module is deposited from the local data Patient image's data are obtained in storage module, and combine the design of the carry out treatment plan of advance parameter, obtain radiotherapy Plans, the radiotherapy treatment planning scheme is stored in the local data storage module in the form of a file, by described Case management module is intended to the Database Systems that data are sent into data server and is managed.The present invention is by patient Image data and treatment plan data stored, remove the acquisition for repeating patient image's data and treatment plan from Formulation, and then shorten treatment and Diagnostic Time, so as to reduce treatment cost.
It should be noted that each embodiment in this specification is described by the way of progressive, each embodiment weight Point explanation is all difference with other embodiment, between each embodiment identical similar part mutually referring to.
The foregoing description of the disclosed embodiments, professional and technical personnel in the field are enable to realize or using the present invention. A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, it is of the invention The embodiments shown herein is not intended to be limited to, and is to fit to and principles disclosed herein and features of novelty phase one The most wide scope caused.

Claims (10)

  1. A kind of 1. radiotherapy treatment planning system, it is characterised in that including:Case management module, treatment planning systems primary module and Local data storage module, wherein,
    The case management module, for entering row data communication with data server, patient image's data are obtained, by given patient Image data download and be stored in the local data storage module, and provide user interface, by accessing the number According to the treatment-related statistical information of database displaying in server, patient image's data include main image sequence and time Level image sequence;
    The treatment planning systems primary module, for obtaining patient image's data from the local data storage module, And the patient image's data and parameter preset provided according to the case management module carry out the design for the treatment of plan, if Radiotherapy treatment planning scheme is counted out, the parameter preset includes:The thing of collimater parameter, robot motion's parameter and therapy apparatus Manage parameter;
    The local data storage module, for storing patient image's data and the radiotherapy treatment planning scheme, institute State radiotherapy treatment planning scheme and the radiotherapy treatment planning scheme is stored in the local datastore mould in the form of a file Block, it is intended to data by the case management module and sends to the Database Systems in the data server be managed.
  2. 2. radiotherapy treatment planning system according to claim 1, it is characterised in that the case management module, for leading to Cross DICOM RT radiotherapies webmaster and import or export DICOM RT data.
  3. 3. radiotherapy treatment planning system according to claim 1, it is characterised in that the case management module includes:Look into Ask, browse with statistic unit, data loading and uploading unit and data interface unit, wherein,
    The inquiry, browse and statistic unit, for by accessing the Database Systems, obtaining and showing the patient column Table;
    Data load and uploading unit, related to uploading for being loaded to patient image's data, the statistical information Data;
    Data interface unit, for carrying out data transmission respectively with the treatment planning systems primary module.
  4. 4. radiotherapy treatment planning system according to claim 1, it is characterised in that the treatment planning systems primary module bag Include:User log-in block, image registration and Fusion Module, profile editor module, plan design module, QA quality assurance plannings are set Module, plan comparison module, plan demonstration module, plan Fusion Module and systematic parameter configuration module are counted, wherein,
    The user log-in block, for verifying the legitimacy of login user and the initialization of user right;Described image is matched somebody with somebody Accurate and Fusion Module, for the registration between different modalities image and generation fused images;
    The profile editor module, for carrying out the extraction and reconstruction of therapy area and sensitive organization's profile, establish the void of patient Intend three-dimensional tissue's model;
    The plan design module, for being designed and optimizing to radiotherapy treatment planning;
    The QA plans design module, the QA for providing patient care plan plan design function;
    The plan comparison module, for carrying out the comparison between different plans, obtain optimized treatment plan;
    The plan demonstration module, for simulating the therapeutic process of Patient treatment plan, and demonstrated;
    The plan Fusion Module, for being overlapped to the dosage field of different plans;
    The systematic parameter configuration module, for configuring the configuration parameter for the treatment of planning systems.
  5. 5. radiotherapy treatment planning system according to claim 4, it is characterised in that described image registration and Fusion Module bag Include:Image registration subelement, registering assessment unit and image fusion unit, wherein,
    Described image registration subelement, for registration, area-of-interest registration, image rigid registration and image shape to be marked Become registration;
    The registering assessment unit, the accuracy and precision of registration are assessed for providing a variety of image display mechanisms auxiliary users;
    Described image integrated unit, the organizational information for two groups of image sequences to be included are merged into same image sequence.
  6. 6. radiotherapy treatment planning system according to claim 4, it is characterised in that the profile editor module includes:VOI ATL administrative unit, contour line delineate the area of computer aided extraction unit and profile operational unit of unit, contour line by hand, Wherein,
    The VOI ATLs administrative unit, for every attribute of the user configuration VOI, self-defined template is created, it is described each Item attribute includes:Transparency when title, type, color and display;
    The contour line delineates unit by hand, and editor is delineated by hand for being provided for the user;
    The area of computer aided extraction unit of the contour line, for carrying out the automatically or semi-automatically information of contour line to the patient Extraction;
    The profile operational unit, the profile collection for being formed to the contour line are operated and edited.
  7. 7. radiotherapy treatment planning system according to claim 4, it is characterised in that the plan design module includes:Meter Draw initialization unit, plan hand-designed unit, plan reverse-engineer unit, Rapid Dose Calculation unit, Program Assessment unit and Adaptive planning unit, wherein,
    The plan initialization unit, parameter is carried out for being initialized to the parameter preset, and to the parameter preset Checking;
    The plan hand-designed unit, concentrates from launched field for user and chooses launched field node and direction, and add by hand Add treatment launched field;
    The plan reverse-engineers unit, for being positioned to the launched field node and direction and the radiotherapy treatment planning Scheme is adjusted;
    The Rapid Dose Calculation unit, the radiological dose field of radiotherapy treatment planning is calculated for providing a variety of dose calculation methodologies;
    The Program Assessment unit, for assessing the radiotherapy treatment planning scheme, and assess the radiological dose field;
    The adaptive planning unit, user is aided in the radiotherapy treatment planning scheme for providing a variety of Plan rescheduling instruments It is improved.
  8. 8. radiotherapy treatment planning system according to claim 7, it is characterised in that the plan initialization unit includes: Parameter initialization unit and Verification unit are treated, wherein,
    The treatment parameter initialization unit, set for carrying out initialization to the treatment parameter of the radiotherapy treatment planning scheme Put;
    The Verification unit, for the treatment parameter of the radiotherapy treatment planning scheme to be verified and veritified.
  9. 9. radiotherapy treatment planning system according to claim 7, it is characterised in that the plan reverse-engineers unit bag Include:Optimization aim design cell and Plan rescheduling unit, wherein,
    The optimization aim design cell, supplied by providing a variety of optimization aim designs based on user's progress radiotherapy The determination for the scheme of drawing;
    The Plan rescheduling unit, it is suitable for being performed to treatment time, launched field quantity, number of nodes, launched field fine setting and launched field Sequence carries out Plan rescheduling.
  10. 10. radiotherapy treatment planning system according to claim 7, it is characterised in that the dose calculation module, for carrying The radiological dose field for the treatment of plan is calculated for a variety of dose calculation methodologies.
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WO2019140886A1 (en) * 2018-01-19 2019-07-25 北京连心医疗科技有限公司 Standardized cloud radiotherapy planning method, storage medium, and system
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