CN108849905A - A kind of compound pesticide composition of fluorine-containing ether bacterium amide - Google Patents
A kind of compound pesticide composition of fluorine-containing ether bacterium amide Download PDFInfo
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- CN108849905A CN108849905A CN201810578134.XA CN201810578134A CN108849905A CN 108849905 A CN108849905 A CN 108849905A CN 201810578134 A CN201810578134 A CN 201810578134A CN 108849905 A CN108849905 A CN 108849905A
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- fluorine
- ether bacterium
- bacterium amide
- weight ratio
- fluorine ether
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title claims abstract description 242
- 241000894006 Bacteria Species 0.000 title claims abstract description 124
- 229910052731 fluorine Inorganic materials 0.000 title claims abstract description 120
- 239000011737 fluorine Substances 0.000 title claims abstract description 120
- 150000001408 amides Chemical class 0.000 title claims abstract description 116
- 239000000203 mixture Substances 0.000 title claims abstract description 51
- 150000001875 compounds Chemical class 0.000 title claims abstract description 38
- 239000000575 pesticide Substances 0.000 title claims abstract description 16
- 125000001153 fluoro group Chemical group F* 0.000 title claims abstract description 11
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims abstract description 109
- 239000000470 constituent Substances 0.000 claims abstract description 47
- 201000010099 disease Diseases 0.000 claims abstract description 36
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 36
- WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000005821 Propamocarb Substances 0.000 claims abstract description 31
- FXYOBYMJDLKKMF-UHFFFAOYSA-N C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1.[F] Chemical compound C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1.[F] FXYOBYMJDLKKMF-UHFFFAOYSA-N 0.000 claims abstract description 18
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 claims abstract description 17
- 239000005756 Cymoxanil Substances 0.000 claims abstract description 17
- CGIHPACLZJDCBQ-UHFFFAOYSA-N acibenzolar Chemical compound SC(=O)C1=CC=CC2=C1SN=N2 CGIHPACLZJDCBQ-UHFFFAOYSA-N 0.000 claims abstract description 17
- OIPMQULDKWSNGX-UHFFFAOYSA-N bis[[ethoxy(oxo)phosphaniumyl]oxy]alumanyloxy-ethoxy-oxophosphanium Chemical compound [Al+3].CCO[P+]([O-])=O.CCO[P+]([O-])=O.CCO[P+]([O-])=O OIPMQULDKWSNGX-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000005797 Iprovalicarb Substances 0.000 claims abstract description 15
- NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 claims abstract description 15
- 239000000375 suspending agent Substances 0.000 claims description 24
- 241000233679 Peronosporaceae Species 0.000 claims description 23
- 239000003094 microcapsule Substances 0.000 claims description 14
- 235000007164 Oryza sativa Nutrition 0.000 claims description 10
- 235000009566 rice Nutrition 0.000 claims description 10
- 241000221785 Erysiphales Species 0.000 claims description 9
- 239000004563 wettable powder Substances 0.000 claims description 8
- -1 acyl Amine Chemical class 0.000 claims description 7
- 239000000839 emulsion Substances 0.000 claims description 6
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004548 suspo-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 241001530056 Athelia rolfsii Species 0.000 claims description 5
- 241000582441 Peronospora tabacina Species 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 32
- 230000000694 effects Effects 0.000 abstract description 18
- BAUQXSYUDSNRHL-UHFFFAOYSA-N pyrimorph Chemical compound C1=CC(C(C)(C)C)=CC=C1C(C=1C=NC(Cl)=CC=1)=CC(=O)N1CCOCC1 BAUQXSYUDSNRHL-UHFFFAOYSA-N 0.000 abstract description 16
- 230000000855 fungicidal effect Effects 0.000 abstract description 5
- 238000001228 spectrum Methods 0.000 abstract description 3
- 238000005406 washing Methods 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 38
- 239000003814 drug Substances 0.000 description 35
- 230000003449 preventive effect Effects 0.000 description 25
- 230000002265 prevention Effects 0.000 description 19
- 240000008067 Cucumis sativus Species 0.000 description 17
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 17
- 231100000820 toxicity test Toxicity 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- 239000002518 antifoaming agent Substances 0.000 description 13
- 239000002270 dispersing agent Substances 0.000 description 13
- 230000003285 pharmacodynamic effect Effects 0.000 description 12
- 239000012071 phase Substances 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 11
- 238000013329 compounding Methods 0.000 description 11
- 238000002474 experimental method Methods 0.000 description 11
- 239000003995 emulsifying agent Substances 0.000 description 10
- 239000002904 solvent Substances 0.000 description 10
- 241000209094 Oryza Species 0.000 description 9
- 230000005764 inhibitory process Effects 0.000 description 9
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 8
- 240000003768 Solanum lycopersicum Species 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 239000008367 deionised water Substances 0.000 description 8
- 229910021641 deionized water Inorganic materials 0.000 description 8
- 238000013401 experimental design Methods 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 8
- 239000000080 wetting agent Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 206010067482 No adverse event Diseases 0.000 description 6
- 230000010165 autogamy Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 206010011732 Cyst Diseases 0.000 description 4
- 241000233614 Phytophthora Species 0.000 description 4
- 208000031513 cyst Diseases 0.000 description 4
- 230000000857 drug effect Effects 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 229920002521 macromolecule Polymers 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 229920000742 Cotton Polymers 0.000 description 3
- 241000209140 Triticum Species 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 238000000498 ball milling Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- UJMWVICAENGCRF-UHFFFAOYSA-N oxygen difluoride Chemical compound FOF UJMWVICAENGCRF-UHFFFAOYSA-N 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 241000123650 Botrytis cinerea Species 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000510928 Erysiphe necator Species 0.000 description 1
- 239000005782 Fluopicolide Substances 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 241000233616 Phytophthora capsici Species 0.000 description 1
- 241000233622 Phytophthora infestans Species 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
- 239000007798 antifreeze agent Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000002242 deionisation method Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005243 fluidization Methods 0.000 description 1
- GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 description 1
- DNJKFZQFTZJKDK-UHFFFAOYSA-N fluopimomide Chemical compound FC1=C(F)C(OC)=C(F)C(F)=C1C(=O)NCC1=NC=C(C(F)(F)F)C=C1Cl DNJKFZQFTZJKDK-UHFFFAOYSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- NWUWYYSKZYIQAE-UHFFFAOYSA-N isopropyl (3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl)carbamate Chemical compound CC(C)OC(=O)NC(C(C)C)C(=O)NC(C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-UHFFFAOYSA-N 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- RXJKFRMDXUJTEX-UHFFFAOYSA-N triethylphosphine Chemical compound CCP(CC)CC RXJKFRMDXUJTEX-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of compound pesticide composition of fluorine-containing ether bacterium amide, effective active composition is active components A and active constituent B, and active components A is selected from fluorine ether bacterium amide, and active constituent B is selected from any one following compound：Cymoxanil, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb, and active components A and the weight ratio of active constituent B are 1: 80~60: 1.The present composition has greater activity to the multiple diseases in various crop, and has apparent synergistic effect, expands fungicidal spectrum.And small, resistance of rainwater washing against, the obvious feature of synergy with dosage.
Description
The application is divisional application, and original application is a logical patent application " a kind of Recompounded pesticide group for fluorine-containing ether bacterium amide
Close object ", original application application No. is 201310403744.3, original application date 2013.09.02.
Technical field
The invention belongs to technical field of pesticide, are related to a kind of compound pesticide composition of fluorine-containing ether bacterium amide in crop disease
On application.
Technical background
Fluorine ether bacterium amide (LH-2010A) selective fungicide fluopicolide more similar than structure has wider array of fungicidal spectrum.
Fluorine ether bacterium amide is to the bacteriostatic activity highest of cotton phytophthora and botrytis cinerea, to Phytophthora capsici and potato late blight
Germ antibacterial work with higher, fluorine ether bacterium amide is obvious to cotton phytophthora bacteriostasis, can significantly inhibit its sclerotium
Generation and mycelium morphology factor, make mycelia branch increase, shorten, is thicker；Fluorine ether bacterium amide has various plants pathogen higher
Bacteriostatic activity, and can obviously inhibit the multinomial physical signs of cotton phytophthora.
In the real process of agricultural production, the problem of controlling disease most easily produces is the generation of disease drug resistance.No
It is compounded with kind ingredient, is to prevent and treat the very common method of resistance disease.Heterogeneity is compounded, and is imitated according to practical application
Fruit, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of pesticide is all to add
And effect, really there is the compounding of synergistic effect seldom, especially synergistic effect is clearly, synergy ratio is very high compounds just more
It is few.Studied by inventor, discovery by fluorine ether bacterium amide and cymoxanil, Propamocarb, propamocarb, phosethyl-Al,
Fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb mutually compound, and have good synergistic effect in a certain range, and
In relation to fluorine ether bacterium amide and cymoxanil, Propamocarb, phosethyl-Al, pyrimorph, fluorine thiazole pyrrole ethyl ketone, phenyl ether methyl cyclic, activation
The related compounding of ester or iprovalicarb, at present at home and abroad there is not yet relevant report.
Summary of the invention
The purpose of the present invention is to propose to a kind of with synergistic function, the fluorine-containing ether bacterium acyl that use cost is low, preventive effect is good
The compound pesticide composition of amine.
The present invention is achieved through the following technical solutions：
A kind of compound pesticide composition of fluorine-containing ether bacterium amide, containing active components A and active constituent B, active components A with
Active constituent B weight ratio is 1: 80~60: 1, and the active components A is selected from fluorine ether bacterium amide, and active constituent B is selected from white urea
One in cyanogen, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb
Kind；Preferably the weight ratio of active components A and active constituent B is 1: 60~40: 1；More preferably fluorine ether bacterium amide and cymoxanil
Weight ratio be 1: 20~10: 1, the weight ratio of fluorine ether bacterium amide and Propamocarb is 1: 30~10: 1, fluorine ether bacterium amide and downy mildew
The weight ratio of prestige hydrochloride is 1: 30~10: 1, and the weight ratio of fluorine ether bacterium amide and phosethyl-Al is 1: 30~10: 1, fluorine ether
The weight ratio of bacterium amide and fluorine thiazole pyrrole ethyl ketone is 1: 20~10: 1, the weight ratio of fluorine ether bacterium amide and pyrimorph is 1: 20~
10: 1, the weight ratio of fluorine ether bacterium amide and Acibenzolar is 1: 10~20: 1, and the weight ratio of fluorine ether bacterium amide and iprovalicarb is 1: 20
~10: 1；Most preferably the weight ratio of fluorine ether bacterium amide and cymoxanil is 1: 9~4: 1, the weight of fluorine ether bacterium amide and Propamocarb
Than being 1: 19~1: 1, the weight ratio of fluorine ether bacterium amide and propamocarb is 1: 19~1: 1, fluorine ether bacterium amide and triethylphosphine
The weight ratio of sour aluminium is 1: 19~1: 1, and the weight ratio of fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone is 1: 9~4: 1, fluorine ether bacterium amide
Weight ratio with pyrimorph is 1: 14~4: 1, and the weight ratio of fluorine ether bacterium amide and Acibenzolar is 1: 4~9: 1, fluorine ether bacterium amide
Weight ratio with iprovalicarb is 1: 9~4: 1.
Bactericidal composition of the invention can be processed into acceptable dosage form in any sterilization, wherein more preferably as needed
Dosage form be that wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspoemulsion, microcapsule suspending agent, micro-capsule are outstanding
Floating-suspending agent, can also be made seed coat agent, suspension seed-coating agent, granule, ultra low volume liquids.
The compound pesticide composition of the fluorine-containing ether bacterium amide is used to prevent and treat the disease of crop；The crop is grain
Crop, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, rhizome
Class crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop；The disease is downy mildew, frost
Phytophthora root rot, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker.
The content of active constituent depends on amount of application when being used alone in bactericidal composition of the invention, also depends on one
The mixed ratio and synergistic effect degree of kind compound and another compound, at the same it is also related with target disease.Usual group
The weight percentage for closing active constituent in object is the 1%~90% of total weight, preferably 5%~80%.According to different
Preparation type, active component content range are different.Liquids in general preparation contains by weight 1%~60% active matter
Matter, preferably 5%~50%；Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~
80%.
In bactericidal composition of the invention at least contain a kind of surfactant, in favor of application when active component in water
Dispersion.Surface-active contents are the 2%~30% of total formulation weight, and surplus is solid or liquid diluent.
Bactericidal composition of the invention can used before through dilution or directly by user.Its preparation can be by ability
The preparation of processing method well known to field technique personnel, i.e., after mixing active constituent with liquid solvent or solid carrier, add
One or more of surfactant such as dispersing agent, stabilizer, wetting agent, binder, disintegrating agent, defoaming agent etc..According to not
Same dosage form can also contain antifreeze known in those skilled in the art etc. in preparation.
Comprising following component and content when wettable powder is made in composition：Active components A 0.5%~60%, activity at
Divide B 0.5%~80%, dispersing agent 1%~12%, wetting agent 1%~8%, filler surplus.
Composition includes following component and content when water dispersible granules are made：Active components A 0.5%~60%, activity at
Point B 0.5%~80%, dispersing agent 1%~12%, wetting agent 1%~8%, disintegrating agent 1%~10%, binder 0~8%,
Filler surplus.
Composition includes following component and content when suspending agent is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, dispersing agent 1%~10%, wetting agent 1%~10%, defoaming agent 0.01%~2%, thickener 0~2%, anti-
Freeze agent 0~8%, deionized water adds to 100%.
Composition includes following component and content when aqueous emulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, solvent 1%~20%, emulsifier 1%~12%, antifreeze 0~8%, defoaming agent 0.01%~2%, thickening
Agent 0~2%, deionized water add to 100%.
Composition includes following component and content when microemulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, emulsifier 3%~25%, solvent 1%~10%, antifreeze 0~8%, defoaming agent 0.01%~2%, go from
Sub- water adds to 100%.
Composition includes following component and content when suspoemulsion is made：Active components A 0.5%~50%, active constituent B
0.5%~50%, emulsifier 1%~10%, dispersing agent 1%~10%, solvent 1%~20%, defoaming agent 0.01%~2%,
Thickener 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspending agent is made：Active components A 0.5%~50%, activity at
Divide B 0.5%~50%, macromolecule cyst material 1%~10%, dispersing agent 2%~10%, solvent 1%~10%, emulsifier
1%~7%, pH adjusting agent 0.01%~5%, defoaming agent 0.01%~2%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspension-suspendinagent agent is made：Active components A 0.5%~50% is lived
It is property ingredient B 0.5%~50%, macromolecule cyst material 1%~12%, dispersing agent 1%~12%, wetting agent 1%~8%, molten
Agent 1%~15%, emulsifier 1%~8%, defoaming agent 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~
5%, deionized water adds to 100%.
Wettable powder the key technical indexes of the invention：
Water dispersible granules the key technical indexes of the invention：
Suspending agent the key technical indexes of the invention：
Aqueous emulsion the key technical indexes of the invention：
Microemulsion the key technical indexes of the invention：
Suspoemulsion the key technical indexes of the invention：
Microcapsule suspending agent the key technical indexes of the invention：
Microcapsule suspension-suspendinagent agent the key technical indexes of the invention：
The advantage of the invention is that：
(1) present composition has good synergy and lasting effect in a certain range, and preventive effect is higher than single dose；(2) agriculture
Medicinal dose is reduced, and is reduced residual quantity of the pesticide on crop, is mitigated environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases
Such as downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker have
Greater activity.
Specific embodiment
Below with reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~13 wettable powder of embodiment
Fluorine ether bacterium amide, active constituent B, dispersing agent, wetting agent, filler are mixed, are uniformly mixed in mixed cylinder, through gas
Stream pulverizer remixes uniformly after crushing, that is, can be made into wettable powder product of the present invention.Specifically it is shown in Table 1.
1 embodiment of table, 1~13 each component and content
14~26 water dispersible granules of embodiment
Fluorine ether bacterium amide, active constituent B, dispersing agent, wetting agent, disintegrating agent, filler etc. are obtained through air-flow crushing together
The partial size needed adds other auxiliary agents such as binder (can add can be not added), obtains granulation materials.Item is quantified into feeding fluidisation
In bed granulating drier after granulation and drying, it can be prepared by water dispersible granules product of the present invention, be specifically shown in Table 2.
2 embodiment of table, 14~26 each component and content
27~39 suspending agent of embodiment
By dispersing agent, wetting agent, defoaming agent, thickener (can add can be not added), antifreeze (can add can be not added), by high speed
Shear-mixed is uniform, fluorine ether bacterium amide, active constituent B is added, ball milling 2~3 hours, make diameter of particle all exist in the ball mill
5 μm hereinafter, surplus is supplied with deionized water, can be prepared by suspending agent product of the present invention, specifically be shown in Table 3.
3 embodiment of table, 27~39 each component and content
40~46 aqueous emulsion of embodiment
Fluorine ether bacterium amide, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；By deionization
Water, antifreeze (can add can be not added), thickener (can add can be not added), defoaming agent mix, at uniform water phase.In high-speed stirring
It mixes down, oily phase is added in water phase, aqueous emulsion product of the present invention is made.Specifically it is shown in Table 4.
4 embodiment of table, 40~46 each component and content
47~53 microemulsion of embodiment
Fluorine ether bacterium amide, active constituent B are dissolved in the homogenizer equipped with solvent, by emulsifier, antifreeze, (can add can
Be not added), defoaming agent, be added in the homogenizer equipped with above-mentioned solution, surplus give after being supplied with deionized water strongly mix simultaneously
It homogenizes, finally obtains the transparent microemulsion product of the present invention of clear appearance.Specifically it is shown in Table 5.
5 embodiment of table, 47~53 each component and content
By cymoxanil, Propamocarb and salt in table 1~5, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or
Iprovalicarb exchanges, and novel formulation can be made.
54~56 suspoemulsion of embodiment
Dispersing agent, defoaming agent, thickener (can add can be not added), antifreeze (can add can be not added) are mixed by high speed shear
Uniformly, fluorine ether bacterium amide is added, in the ball mill ball milling 2~3 hours, makes diameter of particle all at 5 μm hereinafter, fluorine ether bacterium is made
Then amide suspending agents directly emulsify active constituent B, emulsifier, solvent and various auxiliary agents to suspending agent with high speed agitator
In, suspoemulsion product of the present invention is made.Specifically it is shown in Table 6.
6 embodiment of table, 54~56 each component and content
57~59 microcapsule suspending agent of embodiment
Fluorine ether bacterium amide, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, cut
Under tangent condition, by oil be added to containing emulsifier, pH adjusting agent, dispersing agent, defoaming agent aqueous phase solution in, surplus spend from
Sub- water is supplied, and two kinds of materials react in oil-water interfaces, forms high score ascus wall, it is well dispersed that the present composition is made
Microcapsule suspending agent product.Specifically it is shown in Table 7.
7 embodiment of table, 57~59 each component and content
60~62 microcapsule suspension-suspendinagent agent of embodiment
Active constituent B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oily mutually in shearing condition
Under be added to containing emulsifier, pH adjusting agent aqueous phase solution in, well dispersed microcapsule suspending agent is made.By dispersing agent, wet
Profit agent, defoaming agent, thickener (can add can be not added) are uniformly mixed by high speed shear, fluorine ether bacterium amide are added, in the ball mill
Ball milling 2~3 hours, makes diameter of particle all at 5 μm hereinafter, suspending agent is made, suspending agent is then added to microcapsules and is suspended
In the aqueous phase solution of agent, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent of the present composition is made and produces
Product.Specifically it is shown in Table 8.
8 embodiment of table, 60~62 each component and content
The embodiment of the present invention is the method combined using indoor toxicity test and field trial.First pass through indoor virulence survey
It is fixed, the synergy ratio (SR) after two kinds of medicaments compound by a certain percentage is defined, SR < 0.5 is antagonism, 0.5≤SR≤1.5
For summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method：After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 by active constituent content respectively
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures medicament to the virulence of crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) is converted into logarithm (x), with minimum
Square law acquires virulence regression equation (y=a+bx), and thus calculates the EC of every kind of medicament50Value.Simultaneously according to Wadley method
Two medicament different ratio synergy ratios (SR) are calculated, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action,
SR > 1.5 is synergistic effect.Calculation formula is as follows：
Wherein：A, b is respectively active components A and active constituent B ratio shared in combination；
A is fluorine ether bacterium amide；
It is mould that B is selected from cymoxanil, Propamocarb and salt, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or figured silk fabrics
One of prestige kind.
Application Example two：
For trying disease：Cucumber downy mildew, test medicine are provided by applicant, experimental design：It is determined by preliminary experiment
Effective inhibition concentration range of both fluorine ether bacterium amide and cymoxanil different ratio mixture.
Toxicity test result
9 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber downy mildew with cymoxanil
As shown in Table 9, the proportion that fluorine ether bacterium amide compounds prevention and treatment cucumber downy mildew with cymoxanil increases in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all larger than 1.5, both illustrates that in 1 ︰, 80~60 ︰, 1 range, mixture shows synergistic effect, fluorine ether bacterium amide with
The proportion of cymoxanil is 1：20~10: 1, synergistic effect is more prominent, and synergy ratio is 2.30 or more, wherein 1: 9~4: 1 model
The most obvious in enclosing, the proportion that discovery fluorine ether bacterium amide and cymoxanil are tested through applicant is 1 ︰ 20,1 ︰ 15,1 ︰ 10,1 ︰ 9,1 ︰
8,1 ︰ 7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,1 ︰ 1,3 ︰ 2,2 ︰ 1,3 ︰ 1,4 ︰ 1,5 ︰ 1,6 ︰ 1,7 ︰ 1,8 ︰ 1,9 ︰ 1,10 ︰ 1, wherein fluorine
Ether bacterium amide and cymoxanil weight ratio are 1：Synergy ratio is maximum when 3, and synergistic effect is the most obvious.
Application Example three：
For trying disease：Cucumber Blight, test medicine are provided by applicant, experimental design：Fluorine is determined by preliminary experiment
Effective inhibition concentration range of ether bacterium amide and Propamocarb raw medicine and the two different ratio mixture.
Toxicity test result
10 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to Cucumber Blight with Propamocarb
As shown in Table 10, the proportion that fluorine ether bacterium amide compounds cucumber blight disease with Propamocarb increases in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all larger than 1.5, both illustrates that in 1 ︰, 80~60 ︰, 1 range, mixture shows synergistic effect, fluorine ether bacterium amide with
For the proportion of Propamocarb 1: 30~10: 1, synergistic effect is more prominent, and synergy ratio is 2.25 or more, wherein 1: 19~1: 1
It is the most obvious in range, through applicant test the proportion of discovery fluorine ether bacterium amide and Propamocarb be 1 ︰ 30,1 ︰ 25,1 ︰ 20,1 ︰ 19,
1 ︰ 18,1 ︰ 17,1 ︰ 16,1 ︰ 15,1 ︰ 14,1 ︰ 13,1 ︰ 12,1 ︰ 11,1 ︰ 10,1 ︰ 9,1 ︰ 8,1 ︰ 7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,
1 ︰ 1,5 ︰ 1,10 ︰ 1, wherein fluorine ether bacterium amide and Propamocarb weight ratio are 1：Synergy ratio is maximum when 10, and synergistic effect is the brightest
It is aobvious.
Application Example four：
For trying disease：Cucumber downy mildew, test medicine are provided by applicant, experimental design：It is determined by preliminary experiment
Effective inhibition concentration range of fluorine ether bacterium amide and technical-grade fosetyl-aluminum and the two different ratio mixture.
Toxicity test result
11 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber downy mildew with phosethyl-Al
As shown in Table 11, fluorine ether bacterium amide compounds the proportion of prevention and treatment cucumber downy mildew with phosethyl-Al in 1 ︰, 80~60 ︰ 1
When, synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine ether bacterium
For the proportion of amide and phosethyl-Al 1: 30~10: 1, synergistic effect is more prominent, synergy ratio 2.25 or more, wherein
The most obvious in 1: 19~1: 1 range, the proportion that discovery fluorine ether bacterium amide and phosethyl-Al are tested through applicant is 1 ︰ 30,1 ︰
25,1 ︰ 20,1 ︰ 19,1 ︰ 18,1 ︰ 17,1 ︰ 16,1 ︰ 15,1 ︰ 14,1 ︰ 13,1 ︰ 12,1 ︰ 11,1 ︰ 10,1 ︰ 9,1 ︰ 8,1 ︰ 7,1 ︰ 6,1 ︰
5,1 ︰ 4,1 ︰ 3,1 ︰ 2,1 ︰ 1,5 ︰ 1,10 ︰ 1, wherein fluorine ether bacterium amide and phosethyl-Al weight ratio are 1：Synergy ratio is most when 14
Greatly, synergistic effect is the most obvious.
Application Example five：
For trying disease：Tomato blight, test medicine are provided by applicant, experimental design：Fluorine is determined by preliminary experiment
Effective inhibition concentration range of ether bacterium amide and pyrimorph raw medicine and the two different ratio mixture.
Toxicity test result
12 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to tomato blight with pyrimorph
As shown in Table 12, fluorine ether bacterium amide compounds the proportion for preventing and treating tomato blight with pyrimorph in 1 80~60 ︰ 1 of ︰,
Synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine ether bacterium amide
For proportion with pyrimorph 1: 20~10: 1, synergistic effect is more prominent, synergy ratio 2.25 or more, wherein 1: 14~
It is the most obvious in 4: 1 ranges, through applicant test the proportion of discovery fluorine ether bacterium amide and pyrimorph be 1 ︰ 20,1 ︰ 15,1 ︰ 10,
1 ︰ 9,1 ︰ 8,1 ︰ 7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,1 ︰ 1,3 ︰ 2,2 ︰ 1,3 ︰ 1,4 ︰ 1,5 ︰ 1,6 ︰ 1,7 ︰ 1,8 ︰ 1,9 ︰ 1,10 ︰ 1,
Wherein fluorine ether bacterium amide and pyrimorph weight ratio are 1：Synergy ratio is maximum when 5, and synergistic effect is the most obvious.
Application Example six：
For trying disease：Target, test medicine are provided by applicant, experimental design：It is true by preliminary experiment
Determine effective inhibition concentration range of fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone raw medicine and the two different ratio mixture.
Toxicity test result
13 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to target with fluorine thiazole pyrrole ethyl ketone
As shown in Table 13, fluorine ether bacterium amide compounded with fluorine thiazole pyrrole ethyl ketone the proportion of prevention and treatment target 1 ︰ 80~
When 60 ︰ 1, synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine
For the proportion of ether bacterium amide and fluorine thiazole pyrrole ethyl ketone 1: 20~10: 1, synergistic effect is more prominent, synergy ratio 2.25 with
On, wherein it is the most obvious in 1: 9~4: 1 range, the proportion of discovery fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone is tested through applicant
For 1 ︰ 20,1 ︰ 15,1 ︰ 10,1 ︰ 9,1 ︰ 8,1 ︰ 7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,2：3,1 ︰ 1,3 ︰ 2,2 ︰ 1,3 ︰ 1,4 ︰ 1,5 ︰ 1,
6 ︰ 1,7 ︰ 1,8 ︰ 1,9 ︰ 1,10 ︰ 1, wherein fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone weight ratio are 2：Synergy ratio is maximum when 3, increases
Effect effect is the most obvious.
Application Example seven：
For trying disease：Cucumber samping off, test medicine are provided by applicant, experimental design：It is determined by preliminary experiment
Effective inhibition concentration range of fluorine ether bacterium amide and propamocarb raw medicine and the two different ratio mixture.
Toxicity test result
14 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber samping off with propamocarb
As shown in Table 14, fluorine ether bacterium amide compounded with propamocarb the proportion of prevention and treatment cucumber samping off 1 ︰ 80~
When 60 ︰ 1, synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine
For the proportion of ether bacterium amide and propamocarb 1: 30~10: 1, synergistic effect is more prominent, synergy ratio 2.30 with
On, wherein it is the most obvious in 1: 19~1: 1 range, the proportion of discovery fluorine ether bacterium amide and propamocarb is tested through applicant
For 1 ︰ 30,1 ︰ 25,1 ︰ 20,1 ︰ 19,1 ︰ 18,1 ︰ 17,1 ︰ 16,1 ︰ 15,1 ︰ 14,1 ︰ 13,1 ︰ 12,1 ︰ 11,1 ︰ 10,1 ︰ 9,1 ︰ 8,1 ︰
7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,1 ︰ 1,5 ︰ 1,10 ︰ 1, wherein fluorine ether bacterium amide and propamocarb weight ratio are 1：When 10
Synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example eight：
For trying disease：Wheat powdery mildew, test medicine are provided by applicant, experimental design：It is determined by preliminary experiment
Effective inhibition concentration range of fluorine ether bacterium amide and Acibenzolar raw medicine and the two different ratio mixture.
Toxicity test result
15 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to wheat powdery mildew with Acibenzolar
As shown in Table 15, fluorine ether bacterium amide compounds the proportion for preventing and treating wheat powdery mildew with Acibenzolar in 1 80~60 ︰ 1 of ︰,
Synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine ether bacterium amide
For proportion with Acibenzolar 1: 10~20: 1, synergistic effect is more prominent, and synergy ratio is 2.25 or more, wherein 1: 4~9: 1
The most obvious in range, the proportion that discovery fluorine ether bacterium amide and Acibenzolar are tested through applicant is 1 ︰ 10,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰
2,1 ︰ 1,2 ︰ 1,3 ︰ 1,4 ︰ 1,5 ︰ 1,6 ︰ 1,7 ︰ 1,8 ︰ 1,9 ︰ 1,10 ︰ 1,15 ︰ 1,20 ︰ 1, wherein fluorine ether bacterium amide and Acibenzolar weight
Amount is than being 2：Synergy ratio is maximum when 1, and synergistic effect is the most obvious.
Application Example nine：
For trying disease：Downy mildew of garpe, test medicine are provided by applicant, experimental design：It is determined by preliminary experiment
Effective inhibition concentration range of fluorine ether bacterium amide and iprovalicarb raw medicine and the two different ratio mixture.
Toxicity test result
16 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to downy mildew of garpe with iprovalicarb
As shown in Table 16, fluorine ether bacterium amide compounds the proportion for preventing and treating downy mildew of garpe with iprovalicarb in 1 80~60 ︰ 1 of ︰,
Synergy ratio SR is all larger than 1.5, illustrates that the two mixture in 1 ︰, 80~60 ︰, 1 range shows synergistic effect, fluorine ether bacterium amide
For proportion with iprovalicarb 1: 20~10: 1, synergistic effect is more prominent, and synergy ratio is 2.30 or more, wherein 1: 9~4: 1
It is the most obvious in range, through applicant test the proportion of discovery fluorine ether bacterium amide and iprovalicarb be 1 ︰ 20,1 ︰ 15,1 ︰ 10,1 ︰ 9,
1 ︰ 8,1 ︰ 7,1 ︰ 6,1 ︰ 5,1 ︰ 4,1 ︰ 3,1 ︰ 2,2：3,1 ︰ 1,3 ︰ 2,2 ︰ 1,3 ︰ 1,4 ︰ 1,5 ︰ 1,6 ︰ 1,7 ︰ 1,8 ︰ 1,9 ︰ 1,10 ︰ 1,
Wherein fluorine ether bacterium amide and iprovalicarb weight ratio are 2：Synergy ratio is maximum when 3, and synergistic effect is the most obvious.
It is found through experiment that：Fluorine ether bacterium amide compounded with active constituent B after in various crop downy mildew, peronospora tabacina,
The prevention and treatment of epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker has apparent synergy to make
With synergy ratio is 1.5 or more.
Effect experiment part：Test medicine is researched and developed by applicant, is provided, 10% fluorine ether bacterium amide suspending agents of comparison medicament
(autogamy), 10% cymoxanil suspending agent (autogamy), 30% Propamocarb aqua (commercially available), 40% phosethyl-Al wettable powder
(commercially available), 15% pyrimorph suspending agent (autogamy), 10% fluorine thiazole pyrrole ethyl ketone suspending agent (autogamy), 30% propamocarb
Aqua (commercially available), 10% Acibenzolar suspending agent (autogamy), 15% iprovalicarb wettable powder (autogamy).
Ten fluorine ether bacterium amide of Application Example and active constituent B and its compound prevention and treatment cucumber downy mildew pharmacodynamic test
This experiment is arranged in Xi'an City, Shanxi Province, investigates the cucumber downy mildew state of an illness before medicine, is administered for the first time in state of an illness initial stage,
Application in every 7 days is primary, is administered 2 times altogether.7 days after second of application, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
17 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment cucumber downy mildew pharmacodynamic test
As can be seen from Table 17, fluorine ether bacterium amide and active constituent B and its cucumber downy mildew can be effectively prevented after compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects in test scope of medication to target crop.It is right simultaneously
Powdery mildew of cucumber, gray mold also have good preventive effect, and drug effect is up to 96% or more.
Ten monofluoro-ether bacterium amide of Application Example and active constituent B and its compound prevention and treatment rice blast pharmacodynamic test
This test arrangement investigates the rice blast state of an illness before Shaanxi Province's Hanzhong City, medicine, is administered for the first time in state of an illness initial stage,
Application in every 7 days is primary, is administered 2 times altogether.3 days after second of application, disease index is investigated respectively and calculates preventive effect within 7 days, 15 days.It is real
It is as follows to test result：
18 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment rice blast pharmacodynamic test
As can be seen from Table 18, fluorine ether bacterium amide and active constituent B and its rice blast can be effectively prevented after compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long, had no adverse effects in test scope of medication to target crop.It is right simultaneously
Rice sheath blight disease, samping off also have good preventive effect, and drug effect is up to 96% or more.
Ten difluoro ether bacterium amide of Application Example and active constituent B and its compound prevention and treatment apple mildew pharmacodynamic test
This test arrangement investigates the apple mildew state of an illness before Shaanxi Province's Weinan City, medicine, is administered for the first time in state of an illness initial stage,
Application in every 7 days is primary, is administered 2 times altogether.7 days after second of application, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
19 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment apple mildew pharmacodynamic test
As can be seen from Table 19, fluorine ether bacterium amide and active constituent B and its efficiency prevention and treatment apple mildew after compounding, prevention and treatment
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in test scope of medication to target crop.
Ten trifluoro bacterium amide of Application Example and active constituent B and its compound prevention and treatment tomato late blight pharmacodynamic test
This test arrangement investigates the tomato late blight state of an illness before Xi'an City, Shanxi Province, medicine, is administered for the first time in state of an illness initial stage,
Application in every 7 days is primary, is administered 2 times altogether.7 days after second of application, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
20 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment tomato late blight disease pharmacodynamic test
As can be seen from Table 20, fluorine ether bacterium amide and active constituent B and its tomato late blight can be effectively prevented after compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects in test scope of medication to target crop.It is right simultaneously
Graw mold of tomato also has good preventive effect, and drug effect is up to 96% or more.
Ten tetrafluoro ether bacterium amide of Application Example and active constituent B and its compound prevention and treatment downy mildew of garpe pharmacodynamic test
This test arrangement investigates the downy mildew of garpe state of an illness before Shaanxi Province's Weinan City, medicine, is administered for the first time in state of an illness initial stage,
Application in every 7 days is primary, is administered 2 times altogether.7 days after second of application, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
21 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment downy mildew of garpe pharmacodynamic test
As can be seen from Table 21, fluorine ether bacterium amide and active constituent B and its downy mildew of garpe can be effectively prevented after compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects in test scope of medication to target crop.It is right simultaneously
Uncinula necator, gray mold also have good preventive effect, and drug effect is up to 96% or more.
15 fluorine ether bacterium amide of Application Example and active constituent B and its compound prevention and treatment target pharmacodynamic test
This test arrangement investigates the target state of an illness before Shaanxi Province's Weinan City, medicine, applies for the first time in state of an illness initial stage
Medicine, application in every 7 days is primary, is administered 2 times altogether.7 days after second of application, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows：
22 fluorine ether bacterium amide of table and active constituent B and its compound prevention and treatment target pharmacodynamic test
As can be seen from Table 22, fluorine ether bacterium amide and active constituent B and its target can be effectively prevented after compounding,
Control efficiency is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in test scope of medication to target crop.
The test by different places throughout the country obtains afterwards, fluorine ether bacterium amide and cymoxanil, Propamocarb, Propamocarb salt
To the downy mildew in various crop after hydrochlorate, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb compounding
The Common Diseases such as disease, peronospora tabacina, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker
Preventive effect 95% or more, is better than single dose preventive effect, and synergistic effect is obvious.
Claims (6)
1. a kind of compound pesticide composition of fluorine-containing ether bacterium amide, effective active composition is active components A and active constituent B,
It is characterized in that：Active components A and the weight ratio of active constituent B are 1: 80~60: 1, and the active components A is selected from fluorine ether bacterium acyl
Amine, active constituent B are selected from cymoxanil, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, Acibenzolar or figured silk fabrics
One of mould prestige kind.
2. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 1, it is characterised in that：Active components A with
The weight ratio of active constituent B is 1: 60~40: 1.
3. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 2, it is characterised in that：
The weight ratio of fluorine ether bacterium amide and cymoxanil is 1: 20~10: 1；
The weight ratio of fluorine ether bacterium amide and Propamocarb is 1: 30~10: 1；
The weight ratio of fluorine ether bacterium amide and propamocarb is 1: 30~10: 1；
The weight ratio of fluorine ether bacterium amide and phosethyl-Al is 1: 30~10: 1；
The weight ratio of fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone is 1: 20~10: 1；
The weight ratio of fluorine ether bacterium amide and Acibenzolar is 1: 10~20: 1；
The weight ratio of fluorine ether bacterium amide and iprovalicarb is 1: 20~10: 1.
4. the compound pesticide composition of fluorine-containing ether bacterium amide described in any one of claim 1 to 3, it is characterised in that：
Wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspoemulsion, microcapsule suspending agent or micro-capsule is made in composition
Suspension-suspending agent.
5. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 4 is used for
The purposes for preventing and treating crop disease.
6. purposes according to claim 5, it is characterised in that：The disease is downy mildew, peronospora tabacina, epidemic disease, black
Shin disease, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew or canker.
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| CN102845436A (en) * | 2012-09-19 | 2013-01-02 | 山东省联合农药工业有限公司 | Bactericide composition containing fluoro-ether bacterium amide and dimethomorph |
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|---|---|---|---|---|
| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
| CN103444733A (en) * | 2013-05-31 | 2013-12-18 | 山东省联合农药工业有限公司 | Sterilization composition containing fluoroether bacteria amide and iprovalicarb |
| CN104412988A (en) * | 2013-08-28 | 2015-03-18 | 张通 | Antibacterial composition containing fluoride ether bacteria amide and triazoles |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020225242A1 (en) | 2019-05-08 | 2020-11-12 | Bayer Aktiengesellschaft | Active compound combination |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104413031B (en) | 2018-08-03 |
| CN104413031A (en) | 2015-03-18 |
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Effective date of registration: 20191226 Address after: 715500 Pucheng County High-tech Industrial Development Zone, Weinan City, Shaanxi Province Applicant after: Shaanxi Mei Bang Pharmaceutical Group Limited by Share Ltd Address before: 715500 middle section of North Ring Road, Pucheng County, Shaanxi, Weinan Applicant before: Zhang Tong |
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Application publication date: 20181123 |