CN108785591A - Chinese medicine composition and preparation method thereof for treating deficiency-cold in spleen and stomach - Google Patents
Chinese medicine composition and preparation method thereof for treating deficiency-cold in spleen and stomach Download PDFInfo
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Abstract
The present invention provides a kind of Chinese medicine composition and preparation method for treating deficiency-cold in spleen and stomach, and the Chinese medicine composition is composed of the following components：Galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi 7%~9%, orange peel 7%~9%, arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%, pueraria lobata 3%~5%, Semen Lablab Album 3%~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%~5%, black pepper 2%~4%, cloves 2%~4%, Radix Glycyrrhizae 2%~4%.It is dry with maltodextrin and potassium sorbate mixing granulation after adding water to be boiled into paste after above-mentioned component is mixed, sterilizing,.Drug of the present invention has the work(of warming middle-JIAO and strengthening the spleen and stomach and alleviating pain, dampness elimination appetizing, warm pathogenic cold；Entire prescription scientific compatibility, pharmacological property is mild, conditioning balance gastroenteric environment, to human body stomach fanout free region.
Description
Technical field
The invention belongs to the Chinese medicine compositions of integration of drinking and medicinal herbs scope, and in particular to a kind of Chinese medicine for treating deficiency-cold in spleen and stomach
Composition and preparation method thereof.
Background technology
Taste occupy middle coke, and promotion ingesta is digested and assimilated and the conveying of cereal nutrient, so that the whole body vital organs of the human body
And each histoorgan obtains supporting for essence of water and grain.Chinese medicine thinks " The spleen and stomach provide the material basis of the acquired, and qi and blood is the source of metaplasia ", human body
Healthy tendency needs supporting for the gas of the essence of water and grain of taste metaplasia.If spleen injury, fortune of receiving is not normal, and internal organs four limbs lose in supplementing nutrition, then
All kinds of diseases and ailments are all raw.Li Dong Yuan exists《Treatise on the spleen and stomach taste actual situation progress of disease opinion》Middle theory：" abundance of vigour, all by QI of the spleen and stomach without being hindered,
Vigour can then be nourished.If stomach the dominator of QI is weak, eating twice as usual, then QI of the spleen and stomach is both hindered, and vigour cannot also fill, and the institute of all diseases
By giving birth to."
Deficiency-cold in spleen and stomach, YANG QI deficiency, then in Wen Yang, the gas of whole body is powerlessly agitated for internal organs mistake, and all diseases are all raw.Functions of spleen and stomach
Can whether normally be determine human righteousness's prosperity and decline an important factor for, no matter the angle from disease preventing and treating or from body-care, all
It should pay attention to taste first.The pathogenic factor of deficiency-cold in spleen and stomach is mainly eating and drinking without temperance, and eating cold and uncooked food excessively trembles with fear product in, makes the sun of taste
It is depressed；Followed by disgruntled excellent think of, irritability imbalance, perverse and unreasonable manner violate stomach and multiply spleen.The symptom of deficiency-cold in spleen and stomach has：Loss of appetite, abdominal distension, stomachache
Indistinctly, crymodynia is uncomfortable, likes temperature happiness and presses, and pain of empty stomach very, must eat, delay, tired or eat cold or panic attacks or exacerbation after suffering from cold, mouth
It is light not thirsty, general hydroptysis, deficiency of food, spiritlessness and weakness, hands and feet being not warm, aversion to cold and preference for warmth, loose watery stool, pale tongue with white fur, deficient and weak pulse.At present
There are many drug for the treatment of deficiency-cold in spleen and stomach in the market, though there is certain curative effect, there are certain side effect, some drugs for using
It is larger to the stimulation of stomach and intestines, the burden of taste can be aggravated, increases the sense of discomfort of patient during treatment.
Invention content
The object of the present invention is to provide a kind of Chinese medicine compositions for treating deficiency-cold in spleen and stomach, using the treatment of solid decoction of medicinal ingredients
Means reach treating both manifestation and root cause of disease to the treatment of deficiency-cold in spleen and stomach, and therapeutic effect is good, can take for a long time, to human body stomach fanout free region.
The technical solution adopted in the present invention is,
Chinese medicine composition for treating deficiency-cold in spleen and stomach, it is raw materials used composed of the following components by mass percentage：
Galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi 7%~9%, orange peel 7%~
9%, arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%, pueraria lobata 3%~5%, Semen Lablab Album
3%~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%~5%, black pepper 2%~
4%, the mass percent summation of cloves 2%~4%, Radix Glycyrrhizae 2%~4%, the above each component is 100%.
The above-mentioned preparation method for treating deficiency-cold in spleen and stomach Chinese medicine composition, including following operating procedure：
Step 1,
By mass percentage, galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi are weighed
7%~9%, orange peel 7%~9%, arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%,
Pueraria lobata 3%~5%, Semen Lablab Album 3%~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%
~5%, the mass percent summation of black pepper 2%~4%, cloves 2%~4%, Radix Glycyrrhizae 2%~4%, the above each component is
100%；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts decoct 2 hours, add for the second time
The water of 6 times of amounts decocts 2 hours, merges decocting liquid twice, filtering, it is 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density,
Thick paste；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
By mass percentage, thick paste 24%~26.97%, 73%~75.97% and of maltodextrin that step 2 obtains are weighed
The mass percent summation of potassium sorbate 0.01%~0.03%, the above each component is 100%；Thick paste and water are stirred evenly
To whitewashing, the weight ratio of thick paste and water is 1:2；
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating premix, obtain mixed material, so
Pelletize afterwards toward whitewashing on mixed material, finally dry, cool down, discharging, shutdown；
Step 6,
Last whole grain and it is filling to get.
In above-mentioned steps 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 15m3/ h~
25m3/ h, inlet air temperature are set as 80 DEG C~100 DEG C, carry out heating premix 7~15 minutes to material, obtain mixed material；In advance
After mixed, by adjusting air quantity and inlet air temperature so that mixed material temperature reaches 35 DEG C~40 DEG C, then multi-functional fluidisation
Bed starts to whitewash, and spouting velocity is set as 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, due to object after whitewashing
Material aggravates, and temperature reduces, and adjusts air quantity at any time and material is kept fully to jump, and adjusting inlet air temperature at any time makes temperature of charge keep
At 35 DEG C~40 DEG C, whitewashing is closed after the 15min~30min that whitewashes, completes granulation；Multifunctional fluidized bed inlet air temperature is set again
It is set to 100 DEG C material is dried, adjusts air quantity and material is kept fully to jump, when the moisture of material≤2.0%, will enter the wind
Temperature is down to 25 DEG C~45 DEG C, and the temperature of material is made to be reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
In above-mentioned steps 6, the dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and is completed
Whole grain, then the dry particl of selection is fitted into bag complete it is filling.
The beneficial effects of the invention are as follows：There is the work(of warming middle-JIAO and strengthening the spleen and stomach and alleviating pain, dampness elimination appetizing, warm pathogenic cold；Entire prescription
Scientific compatibility, pharmacological property is mild, integration of drinking and medicinal herbs, and each drug is mutually coordinated, the healthy tendency of quick hair tonic stomach, conditioning balance gastroenteric environment,
It to human body stomach fanout free region, has no toxic and side effect to human body, can take for a long time, treating both manifestation and root cause of disease is reached to the treatment of deficiency-cold in spleen and stomach.
Specific implementation mode
The present invention provides a kind of Chinese medicine composition for treating deficiency-cold in spleen and stomach, raw materials used by mass percentage by following
Group is grouped as：
Galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi 7%~9%, orange peel 7%~
9%, arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%, pueraria lobata 3%~5%, Semen Lablab Album
3%~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%~5%, black pepper 2%~
4%, the mass percent summation of cloves 2%~4%, Radix Glycyrrhizae 2%~4%, the above each component is 100%.
The pharmacological action of Chinese medicine of the present invention is as follows：
Galangal：Warm stomach antiemetic, eliminating cold to stop pain are used for coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.
Nutmeg：Acrid in flavour and warm in nature, returns spleen stomach large intestine channel middle benefit gas promoting the circulation of qi, relieving diarrhea with astringents is used for deficiency-cold in spleen and stomach, endless diarrhea, gastral cavity abdomen
Distending pain, deficiency of food vomiting.
Chinese cassia tree：Pungent, sweet, big heat returns kidney spleen conscience through mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian, for sun
Impotence Gong Leng, waist and knee crymodynia, deficiency of the kidney and dyspnea, deficient yang with upper manifestation, dizziness hot eyes, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia stomachache, dysmenorrhoea are closed
Through.
Fructus amomi：Dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting lets out
It rushes down, pernicious vomiting, fetal irritability.
Orange peel：Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Arillus longan：Sweet, warm, thoughts of returning home the spleen channel tonifying heart and spleen, nourishing blood and tranquilization.For insufficiency of vital energy and blood, palpitaition is seized with terror secondary, forgetful mistake
It sleeps, blood deficiency chlorosis.
Wrinkled giant hyssop：It eliminates dampness with aromatics and middle preventing or arresting vomiting, delivers relieving summer-heat, be used for turbi damp obstructing in middle-JIAO, the vomiting of gastral cavity ruffian, summer-heat and damp table disease, at the beginning of damp-warm syndrome
It rises, burnout of generating heat is uncomfortable in chest not relax, and cold-dampness closes heat, and abdominal pain is vomited and diarrhoea, nasosinusitis headache.
Chinese yam：Sweet and neutral returns skin lung kidney channel tonifying spleen nourishing the stomach, engender liquid and benefic lung to be used for spleen eating less, endless diarrhea, deficiency syndrome of the lung asthma
Cough, emission due to the kidney deficiency, under, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, diarrhea loose stool, leukorrhea mistake
It is more.
Fingered citron：Pungent, bitter, acid, warm, Return liver taste lung channel dispersing stagnated hepatoqi and stomach and alleviating pain are eliminating dampness and eliminating phlegm, are used for stagnation of liver-QI and stomach-QI,
Distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.
Pueraria lobata：Expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid to quench thirst, promoting eruption, Shengyang Zhixie, clearing and activating the channels and collaterals, relieving alcoholism, is used for fever caused by exogenous pathogens head
Bitterly, stiff nape and back, it is thirsty, it quenches one's thirst, measles without adequate eruption, hot dysentery, diarrhea, dizziness and headache, hemiplegia, chest impediment and cardialgia, during wine poison is hindered.
Semen Lablab Album：It is sweet, tepor, returns spleen stomach invigorating the spleen for eliminating dampness, and in relieve summer heat.For weakness of the spleen and the stomach, loss of appetite, big loose stool
It writes, leukorrhea, summer-heat and damp is vomited and diarrhoea, abdominal distension uncomfortable in chest.Semen Lablab Album invigorating the spleen for eliminating dampness is fried, splenasthenic diarrhea, leukorrhea are used for.
Poria cocos：Clearing damp and promoting diuresis, invigorating the spleen, calming heart are used for oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind
Uneasiness, insomnia of palpitating with fear.
The membrane of a chicken's gizzard：Stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil are used for dyspepsia, vomiting dysentery, and infantile malnutrition is lost
Urine, seminal emission, the puckery pain of stone forest, costalgia that courage is swollen.
Hawthorn：For the sweet tepor returns spleen stomach and liver of acid through food digesting stomach fortifying, scattered stasis changes turbid lipid-loweringing.For meat stagnation, gastral cavilty is swollen
It is full, diarrhea dysentery abdominal pain, extravasated blood Amenorrhea, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipidemia.
Malt：Sweet and neutral, returns spleen stomach promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, delaactation dissipate-swelling, be used for dyspepsia, abdominal distention,
Spleen eating less, milk smoulders, swollen breasts, women weans, liver depression costalgia, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
Black pepper：Warming spleen and stomach for dispelling cold, lower gas, dissolving phlegm are used for gastrofrigid vomiting, abdominal pain diarrhea, loss of appetite, epilepsy abundant expectoration.
Cloves：It is acrid in flavour and warm in nature.Returns spleen stomach lung kidney channel middle benefit gas drop is inverse, tonifies the kidney and support yang.It is vomitted for deficiency-cold in spleen and stomach hiccup, deficiency of food is stopped
It rushes down, trusted subordinate's crymodynia, impotence due to deficiency of the kidney.
Radix Glycyrrhizae：Sweet and neutral.Thoughts of returning home lung taste are clearing heat and detoxicating through invigorating the spleen and benefiting qi, and remove phlegm and relieving cough, relieving spasm to stop pain, coordinating the drug actions of a prescription.
For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug poison
Property is strong.
Nutmeg, Chinese cassia tree, arillus longan, galangal, black pepper, cloves, warm stomach cold removing；It is fructus amomi, wrinkled giant hyssop, orange peel, pueraria lobata, white
Hyacinth bean, fingered citron, invigorating the spleen qi-regulating relieve the pain；Chinese yam, Radix Glycyrrhizae, Poria cocos, QI invigorating tonifying spleen；Malt, the membrane of a chicken's gizzard, hawthorn, promoting digestion and removing indigestion；18 kinds
Drug closes and has the work(of warm stomach invigorating the spleen, and to deficiency-cold in spleen and stomach, stagnation of the circulation of vital energy pain person is particularly suitable, is the good merchantable brand of deficiency-cold in spleen and stomach disease.
Chinese medicine composition of the present invention is 10 grams oral every time by the way of oral, 2 times a day, a month as a treatment course.
With reference to specific embodiment, the present invention is described in detail.
Embodiment 1
Preparation method for treating deficiency-cold in spleen and stomach Chinese medicine composition, including following operating procedure：
Step 1,
Weigh galangal 11kg, nutmeg 13kg, Chinese cassia tree 7kg, fructus amomi 8kg, orange peel 8kg, arillus longan 6kg, wrinkled giant hyssop 4kg,
Chinese yam 5kg, fingered citron 3kg, pueraria lobata 5kg, Semen Lablab Album 5kg, Poria cocos 4kg, the membrane of a chicken's gizzard 5kg, hawthorn 3kg, malt 5kg, black pepper
2kg, cloves 4kg, Radix Glycyrrhizae 2kg；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts decoct 2 hours, add for the second time
The water of 6 times of amounts decocts 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.35 (60 DEG C)；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
Weigh thick paste 20.5kg, maltodextrin 61.5kg and potassium sorbate 20g；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 20m3/ h, inlet air temperature setting
It is 90 DEG C, heating premix is carried out 10 minutes to material, obtains mixed material；After premix, by adjusting air quantity and into wind-warm syndrome
Degree so that mixed material temperature reaches 36 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is set as 17rpm, atomization
Pressure is 1.70bar, and since material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and material is kept fully to jump, and at any time
Adjusting inlet air temperature makes temperature of charge be maintained at 36 DEG C, closes whitewashing after the 20min that whitewashes, completes granulation；Again by multi-functional fluidisation
The inlet air temperature of bed is set as 100 DEG C material is dried, and adjusts air quantity and material is kept fully to jump, when material moisture≤
When 2.0%, inlet air temperature is down to 25 DEG C, the temperature of material is made to be reduced to 25 DEG C, finally discharging shutdown；
Step 6,
The dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and completes whole grain, then will
The dry particl of selection be fitted into bag complete it is filling.
Embodiment 2
Preparation method for treating deficiency-cold in spleen and stomach Chinese medicine composition, including following operating procedure：
Step 1,
Weigh galangal 12kg, nutmeg 12kg, Chinese cassia tree 8kg, fructus amomi 9kg, orange peel 7kg, arillus longan 6kg, wrinkled giant hyssop 5kg,
Chinese yam 5kg, fingered citron 4kg, pueraria lobata 5kg, Semen Lablab Album 3kg, Poria cocos 3kg, the membrane of a chicken's gizzard 5kg, hawthorn 5kg, malt 4kg, black pepper
3kg, cloves 2kg, Radix Glycyrrhizae 2kg；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts decoct 2 hours, add for the second time
The water of 6 times of amounts decocts 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.20 (60 DEG C)；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
Weigh thick paste 24kg, maltodextrin 75.97kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing,
The weight ratio of thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 25m3/ h, inlet air temperature setting
It is 80 DEG C, heating premix is carried out 7 minutes to material, obtains mixed material；After premix, by adjusting air quantity and into wind-warm syndrome
Degree so that mixed material temperature reaches 40 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is set as 15rpm, atomization
Pressure is 1.50bar, and since material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and material is kept fully to jump, and at any time
Adjusting inlet air temperature makes temperature of charge be maintained at 40 DEG C, closes whitewashing after the 15min that whitewashes, completes granulation；Again by multi-functional fluidisation
The inlet air temperature of bed is set as 100 DEG C material is dried, and adjusts air quantity and material is kept fully to jump, when material moisture≤
When 2.0%, inlet air temperature is down to 35 DEG C, the temperature of material is made to be reduced to 35 DEG C, finally discharging shutdown；
Step 6,
The dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and completes whole grain, then will
The dry particl of selection be fitted into bag complete it is filling.
Embodiment 3
Preparation method for treating deficiency-cold in spleen and stomach Chinese medicine composition, including following operating procedure：
Step 1,
Weigh galangal 13kg, nutmeg 12kg, Chinese cassia tree 8kg, fructus amomi 9kg, orange peel 7kg, arillus longan 5kg, wrinkled giant hyssop 6kg,
Chinese yam 3kg, fingered citron 5kg, pueraria lobata 4kg, Semen Lablab Album 4kg, Poria cocos 4kg, the membrane of a chicken's gizzard 4kg, hawthorn 3kg, malt 3kg, black pepper
3kg, cloves 3kg, Radix Glycyrrhizae 4kg；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts decoct 2 hours, add for the second time
The water of 6 times of amounts decocts 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.30 (60 DEG C)；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
Weigh thick paste 26.97kg, maltodextrin 73kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing,
The weight ratio of thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 15m3/ h, inlet air temperature setting
It is 100 DEG C, heating premix is carried out 12 minutes to material, obtains mixed material；After premix, by adjusting air quantity and into wind-warm syndrome
Degree so that when mixed material temperature reaches 38 DEG C, then multifunctional fluidized bed to start to whitewash, spouting velocity is set as 18rpm, mist
Change pressure is 2.0bar, and since material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and material is kept fully to jump, and with
When adjust inlet air temperature temperature of charge made to be maintained at 38 DEG C, close whitewashing after the 30min that whitewashes, complete granulation；Again by multi-functional stream
The inlet air temperature of change bed is set as 100 DEG C and material is dried, and adjusts air quantity and material is kept fully to jump, when the moisture of material
When≤2.0%, inlet air temperature is down to 30 DEG C, the temperature of material is made to be reduced to 30 DEG C, finally discharging shutdown；
Step 6,
The dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and completes whole grain, then will
The dry particl of selection be fitted into bag complete it is filling.
Embodiment 4
Preparation method for treating deficiency-cold in spleen and stomach Chinese medicine composition, including following operating procedure：
Step 1,
Weigh galangal 13kg, nutmeg 11kg, Chinese cassia tree 9kg, fructus amomi 7kg, orange peel 9kg, arillus longan 7kg, wrinkled giant hyssop 5kg,
Chinese yam 4kg, fingered citron 3kg, pueraria lobata 3kg, Semen Lablab Album 3kg, Poria cocos 5kg, the membrane of a chicken's gizzard 3kg, hawthorn 4kg, malt 5kg, black pepper
4kg, cloves 2kg, Radix Glycyrrhizae 3kg；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts decoct 2 hours, add for the second time
The water of 6 times of amounts decocts 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.40 (60 DEG C)；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
Weigh thick paste 24.02kg, maltodextrin 75.97kg and potassium sorbate 10g；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 20m3/ h, inlet air temperature setting
It is 95 DEG C, heating premix is carried out 15 minutes to material, obtains mixed material；After premix, by adjusting air quantity and into wind-warm syndrome
Degree so that mixed material temperature reaches 35 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is set as 20rpm, atomization
Pressure is 1.70bar, and since material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and material is kept fully to jump, and at any time
Adjusting inlet air temperature makes temperature of charge be maintained at 35 DEG C, closes whitewashing after the 25min that whitewashes, completes granulation；Again by multi-functional fluidisation
The inlet air temperature of bed is set as 100 DEG C material is dried, and adjusts air quantity and material is kept fully to jump, when material moisture≤
When 2.0%, inlet air temperature is down to 45 DEG C, the temperature of material is made to be reduced to 45 DEG C, finally discharging shutdown；
Step 6,
The dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and completes whole grain, then will
The dry particl of selection be fitted into bag complete it is filling.
Clinical data
1, case selection：
In order to verify the effect of Chinese medicine composition of the present invention, in December, -2017 in May, 2016 selects the taste made a definite diagnosis empty
70 clinical observations of cold patient, male 38, women 32, the age is 25 years old minimum, the oldest 65 years old, average age 42.5
Year；The course of disease is most 2 weeks short, longest 3 years.
Make a definite diagnosis standard：
(1) main syndromes：1. vague epigastralgia；2. meeting cold very pain；3. gasteremphraxis belch after food；4. deficiency of food, indigestion and loss of appetite；5. gastral cavilty is empty
Abdominal pain very, must eat pain and subtract；6. loose watery stool or diarrhea.
(2) secondary syndrome：1. general hydroptysis or pantothenic acid；2. happiness heat happiness is pressed；3. spiritlessness and weakness；4. hands and feet being not warm；5. chilly
Happiness is warm；6. light red tongne, thin white fur of tongue or white greasy, tongue body fat big, tongue side point have indentation, deep thready pulse.
(3) card type determines：Have 2 main symptoms, then adds 2 cards；Or have 1 main symptom, then add 3 cards.
Exclusion criteria:
1. acute inflammations patients such as gastral cavilty portion is red, swollen, the hot, heat that occurs together bitterly；
2. chronic gastritis and merging with other lesions patient such as atrophic gastritis, peptic ulcer；Stomach, oesophagus etc., which have, to disappear
Change road organic disease patient；
3. taking other drugs (such as hormone) curer；
4. with internal organs such as liver kidney, angiocarpy compared with severe case.
2, medicament selection：
Patient takes Chinese medicine of the present invention, and 2 times a day, each 10g, warm water delivery service in half an hour after meal is treated for 30 days for one
Journey, continuously takes 1 to 3 courses for the treatment of, and serious patient increases the amount of discretion.
3, symptom integral criterion：
3, efficacy determination：
Judge that curative effect situation, the calculation formula of therapeutic index N are according to therapeutic index N：N=(total mark-treatments before treatment
Total mark afterwards) preceding total mark × 100% of/treatment.
(1) it cures：Symptom, sign completely disappear；N=1；
(2) effective：Symptom, the sign overwhelming majority improve；N >=75%；
(3) effectively：Symptom, sign make moderate progress；50%≤N < 75%；
(3) invalid：Symptom, sign are not improved；N < 50%.
4, result：
It takes in 70 patients of drug of the present invention, cures 42, effective 12, effective 10, invalid 6；Cure rate
It is 60%, total effective rate 91.42%.
Case 1
Zhang, female, 43 years old, Xi'an City, Shanxi Province people from Yanliang District.Patient's readme：Nearly half a year, gastral cavilty often have a dull ache, often
Cause gastral cavity pain aggravation because weather turns cold, eats cold product, with the cold and cool sense of stomach when pain, aversion to cold and preference for warmth, stool is often dilute
It is half congealed, deficiency of food, spiritlessness and weakness, hands and feet being not warm.It is medical to come here, patient size is partially thin, pale complexion, and nail color is light, white and greasy fur, arteries and veins
Weak inability.It is diagnosed as：Deficiency-cold in spleen and stomach.Drug of the present invention is continuously taken after 2 months, carrys out here further consultation：The case where gastral cavity pain, has
Improved, diet increases.Continue to take drug of the present invention 2 months, patient has rosy cheeks, and stomachache, symptom of diarrhea disappear, and diet is just
Often, energetic.Follow-up half a year is without recurrence, recovery from illness.
Case 2
It is tall certain, female, 35 years old, Shaanxi Province Weinan City Dali County.Epigastric pain nearly half a year, belch of often having the hiccups, gastric disorder causing nausea acid are easy
Nausea has been easy peculiar smell, borborygmus in the mouth, and loose watery stool one day 2-3 times, is liked drinking hot soup, and sealing upper abdomen with hot-water bottle can feel
It is very comfortable.It is medical to come here, patient's sallow complexion, thin white fur of tongue, deep thready pulse.It is diagnosed as：Deficiency-cold in spleen and stomach.Continuously take the present invention
After drug 3 months, epigastric discomfort symptom disappears, and stool is normal, and diet restores normal, and all symptoms disappear, recovery from illness, for consolidate curative effect after
January is taken in continuous consolidation.
Case 3
Huang, man, 40 years old, Xianyang, Shanxi province city Jingyang County.Patient's readme：Tastelessness, do not feel like eating, abdominal fullness and distention,
Aversion to cold and cold limbs, deficiency of QI with disinclination to talk, upper abdomen crymodynia, borborygmus, loose stool, belly, which is had loose bowels, not to be molded, and is defecated 3-5 times within one day.It is medical to come here,
Patient's sallow complexion, thin white fur of tongue, deep thready pulse.It is diagnosed as：Deficiency-cold in spleen and stomach.Drug of the present invention is continuously taken after 2 months, upper abdomen is not
Suitable symptom disappears, and the symptoms such as abdominal pain, borborygmus mitigate, and stool is normal, defecates once a day, and stool forming, diet restores normal；
To consolidate curative effect, continue to take this drug 2 months, all symptoms disappear, recovery from illness.
Claims (4)
1. the Chinese medicine composition for treating deficiency-cold in spleen and stomach, which is characterized in that raw materials used by mass percentage by following components
Composition：
Galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi 7%~9%, orange peel 7%~9%,
Arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%, pueraria lobata 3%~5%, Semen Lablab Album 3%
~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%~5%, black pepper 2%~4%, fourth
The mass percent summation of perfume 2%~4%, Radix Glycyrrhizae 2%~4%, the above each component is 100%.
2. for treating the preparation method of deficiency-cold in spleen and stomach Chinese medicine composition described in a kind of claim 1, which is characterized in that including with
Lower operating procedure：
Step 1,
By mass percentage, weigh galangal 11%~13%, nutmeg 11%~13%, Chinese cassia tree 7%~9%, fructus amomi 7%~
9%, orange peel 7%~9%, arillus longan 5%~7%, wrinkled giant hyssop 4%~6%, Chinese yam 3%~5%, fingered citron 3%~5%, pueraria lobata
3%~5%, Semen Lablab Album 3%~5%, Poria cocos 3%~5%, the membrane of a chicken's gizzard 3%~5%, hawthorn 3%~5%, malt 3%~
5%, the mass percent summation of black pepper 2%~4%, cloves 2%~4%, Radix Glycyrrhizae 2%~4%, the above each component is
100%；
Step 2,
18 taste raw materials in step 1 are added water to cook twice, add the water of 10 times of amounts for the first time, are decocted 2 hours, second plus 6 times
The water of amount decocts 2 hours, merges decocting liquid twice, filtering, it is the thick of 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density,
Cream；
Step 3,
Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is spare；
Step 4,
By mass percentage, thick paste 24%~26.97%, maltodextrin 73%~75.97% and sorb that step 2 obtains are weighed
The mass percent summation of sour potassium 0.01%~0.03%, the above each component is 100%；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating premix, obtain mixed material, it is then past
Whitewashing is pelletized on mixed material, is finally dried, is cooled down, discharging, shutting down；
Step 6,
Last whole grain and it is filling to get.
3. being used to treat the preparation method of deficiency-cold in spleen and stomach Chinese medicine composition according to claim 2, it is characterised in that：The step
In rapid 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set as 15m3/ h~25m3/ h, inlet air temperature
80 DEG C~100 DEG C are set as, heating premix is carried out 7~15 minutes to material, obtains mixed material；After premix, pass through tune
Save air quantity and inlet air temperature so that mixed material temperature reaches 35 DEG C~40 DEG C, then multifunctional fluidized bed to start to whitewash, whitewashing
Speed is set as 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, and since material aggravates after whitewashing, temperature reduces,
Adjusting air quantity at any time keeps material fully to jump, and adjusting inlet air temperature at any time makes temperature of charge be maintained at 35 DEG C~40 DEG C, spray
Whitewashing is closed after starching 15min~30min, completes granulation；Multifunctional fluidized bed inlet air temperature is set as 100 DEG C to material again
Be dried, adjust air quantity and material is kept fully to jump, when the moisture of material≤2.0%, by inlet air temperature be down to 25 DEG C~
45 DEG C, the temperature of material is made to be reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
4. being used to treat the preparation method of deficiency-cold in spleen and stomach Chinese medicine composition according to claim 2, it is characterised in that：The step
In rapid 6, the dry particl that step 5 obtains is chosen into the particle between the mesh of 14 mesh~60 on shaking screen and completes whole grain, it then will choosing
The dry particl taken be fitted into bag complete it is filling.
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Application publication date: 20181113 |