CN108743474B

CN108743474B - Ointment-shaped baby hip-protecting cream and preparation method thereof

Info

Publication number: CN108743474B
Application number: CN201810686394.9A
Authority: CN
Inventors: 林雪萍; 李雪竹; 陈晓朋
Original assignee: Guangzhou Ousia Industrial Co ltd
Current assignee: Guangzhou Ousia Industrial Co ltd
Priority date: 2018-06-28
Filing date: 2018-06-28
Publication date: 2021-05-14
Anticipated expiration: 2038-06-28
Also published as: CN108743474A

Abstract

The invention discloses ointment-shaped baby hip-protecting cream and a preparation method thereof, and relates to the technical field of daily skin-care products. The baby hip-protecting cream is mainly prepared from mixed waxes, vegetable oil, vegetable fat, plant extraction essence and an antioxidant, and specifically comprises the following components: 5.000-20.000% of mixed wax, 7.000-70.000% of vegetable oil, 5.000-10.000% of vegetable fat, 0.001-7.000% of plant extract essence and 0.25-1.500% of antioxidant. The ointment-shaped baby hip pad is mild and non-irritant, can separate the skin of a baby from a paper diaper, avoids friction damage to the delicate skin of the baby, and has the effects of bacteriostasis, inflammation diminishing and relieving.

Description

Ointment-shaped baby hip-protecting cream and preparation method thereof

Technical Field

The invention relates to a baby hip-protecting cream, belongs to the technical field of daily chemicals, and particularly relates to an ointment-shaped baby hip-protecting cream and a preparation method thereof.

Background

With the widespread use of diapers, more and more new-born babies have more and more skin problems due to the use of diapers. The problem of red buttocks, like babies, is a problem that afflicts many fathers and mothers. The skin of the baby is very delicate and sensitive, when the baby wears the diaper for a long time, the wet diaper often rubs the skin of the baby due to urine immersion, so that a large amount of germs are easily propagated on the surface of the skin, the red buttocks and even diaper rash are easily generated, the red spots are very itchy and uncomfortable for the baby, and the skin erosion and damage are also caused in some serious cases.

In view of this, a great deal of research on infant hip pads has been conducted in the prior art. However, most of the hip-care creams in the market are emulsified creams or ointments, and these hip-care creams generally comprise chemical grease, zinc oxide, talcum powder, essence, water, emulsifier, preservative, humectant and the like.

The purpose of using these hip-pads is to form a barrier protective film on the skin surface to relieve the "red buttocks" of the baby, but it does not have a soothing and repairing effect on the damaged skin that has developed the "diaper rash" symptom, but rather is more irritating, since the preservatives added to these formulations to prevent the growth of microorganisms in the water have a certain irritation.

Moisturizers such as glycerin, 1, 3-butylene glycol and the like added for moisturizing are added in large amounts to cause heat generation and further irritate the skin.

Disclosure of Invention

In order to overcome the defects of the prior art, the invention aims to provide the baby hip pad cream in the oil cream shape, which is mild and non-irritant, can isolate the skin of a baby from a paper diaper, avoids the friction damage to the delicate skin of the baby, and has the effects of bacteriostasis, inflammation diminishing and relieving.

The invention also aims to provide a preparation method of the ointment-shaped baby hip pad cream, which is mild and non-irritant, can isolate the skin of a baby from a paper diaper, avoids friction damage to the delicate skin of the baby, and has the effects of bacteriostasis, inflammation diminishing and relieving.

The technical purpose of the invention is realized by the following technical scheme.

The ointment-shaped baby hip pad cream disclosed by the invention comprises the following raw materials:

5.000-20.000% of mixed wax, 7.000-70.000% of vegetable oil, 5.000-10.000% of vegetable fat, 0.001-7.000% of plant extract essence and 0.25-1.500% of antioxidant.

Further, the ointment-shaped baby hip-protecting cream disclosed by the invention comprises the following raw materials:

sweet almond oil 2.000% -40.000%, olive fruit oil 5.000% -30.000%, shea butter 5.000% -10.000%, grape seed oil 1.000% -7.000%, beeswax 3.000% -10.000%, sunflower seed wax 2.000% -10.000%, candelilla wax 1.000% -5.000%, lavender oil 0.001% -0.050%, avocado oil 0.100% -0.800%, vitamin E0.2500% -1.500%, sunflower seed oil 0.005% -0.200%, calendula oil 0.005% -0.050%, melaleuca alternifolia leaf oil 0.010% -0.400%, chamomile leaf extract/Glycyrrhiza glabra root extract/Glycyrrhiza glabra leaf extract/Rosmarinus officinalis leaf extract/Scutellaria baicalensis root extract/Polygonum cuspidatum root extract 0.100% -5.000%.

The above-mentioned components may preferably be:

sweet almond oil 9.000% -40.000%, olive fruit oil 10.000% -30.000%, shea butter 7.000% -10.000%, grape seed oil 5.000% -7.000%, beeswax 5.000% -10.000%, sunflower seed wax 5.000% -10.000%, candelilla wax 3.000% -5.000%, lavender oil 0.005% -0.050%, avocado oil 0.500% -0.800%, vitamin E0.5000% -1.500%, sunflower seed oil 0.010% -0.200%, calendula oil 0.010% -0.050%, melaleuca alternifolia leaf oil 0.100% -0.400%, chamomile leaf extract/Glycyrrhiza glabra root extract/Glycyrrhiza glabra leaf extract/Rosmarinus officinalis leaf extract/Scutellaria baicalensis root extract/Polygonum cuspidatum root extract 0.500% -5.000%.

The above-mentioned components may be more preferably:

sweet almond oil 15.000% -40.000%, olive fruit oil 20.000% -30.000%, shea butter 7.000% -10.000%, grape seed oil 5.000% -7.000%, beeswax 7.000% -10.000%, sunflower seed wax 7.000% -10.000%, candelilla wax 3.000% -5.000%, lavender oil 0.010% -0.050%, avocado oil 0.500% -0.800%, vitamin E0.7000% -1.500%, sunflower seed oil 0.090% -0.200%, calendula oil 0.010% -0.050%, melaleuca alternifolia leaf oil 0.20% -0.400%, chamomile leaf extract/asiatic glorybower root extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/giant knotweed root extract 1.500% -5.000%.

Furthermore, the sweet almond oil is widely used for skin care products, is beneficial to endowing the skin with elasticity and softness, has no greasy feeling when being applied, is very smooth, can prevent the excessive loss of water through the epidermis, has high vitamin E content, can protect cell membranes, has low melting point, good stability in cold weather, can keep transparency, is not easy to deteriorate, is harmless to the skin, and can not cause acute (primary) irritation and allergy.

The olive fruit oil is from the fruit of green olive, contains less linoleic acid, is not easy to oxidize compared with other liquid oil, is often applied to skin cream, anti-wrinkle cream, massage oil and the like, has the same permeability to skin as common vegetable oil, is better than mineral oil, is harmless to skin, and does not cause acute (primary) skin irritation and allergy.

The shea butter has excellent moisturizing, soft moistening and moisturizing properties, has natural active effects, contains triterpene esters, can effectively resist inflammation, UV injury and skin problems caused by environment, protects collagen, delays aging, and can promote the generation of collagen.

The grape seed oil is light green or light yellow grape seed oil produced by refining dark green grape seed extract, is ideal base oil of other active ingredients, and is also healthy edible oil, so that the grape seed oil is well known and has the effects of nourishing and moisturizing, softening skin, resisting oxidation, fading color spots, sterilizing and diminishing inflammation.

The beeswax has excellent effects of nourishing, moisturizing and repairing injury, effectively cures lip desquamation, can absorb oxygen free radicals which can cause skin oxidation, and has activities of oxidation resistance, antibiosis and antiphlogosis. Beeswax will not cause adverse reaction to skin and acute (one-time) irritation and allergy.

The sunflower seed wax is obtained by completely hydrogenating sunflower seed oil through special hardening and purifying processes, is flaky vegetable oil, has high melting point and excellent stability, has good compatibility with various waxes, has the advantages of the sunflower seed oil, and can be used as a substitute of microcrystalline wax.

The avocado oil is obtained from the pulp of avocado, the dry pulp contains 40-80% by weight of oil, is natural and green, can be widely used as a lubricant in cosmetics to smooth skin, has strong permeability to skin to facilitate the transmission of active substances into skin, can be used for treating skin wounds and skin diseases, has no adverse effect on skin, does not cause acute (primary) irritation and allergy, and has faster permeability than sweet almond oil and olive oil.

The vitamin E has the core effect of strong oxidation resistance, can capture free radicals generated by UV irradiation and environmental pollution, prevent lipid peroxidation of cells or tissues, prevent the formation of sunburn cells, improve the softness of skin, improve the moisture retention of the skin and reduce skin inflammation, and is the most important protective vitamin for the skin.

The sunflower seed oil contains abundant oleic acid, linoleic acid and linolenic acid, the linoleic acid is synthesized by organisms and is a component of cell membranes, so that the sunflower seed oil has the properties of moisturizing, promoting cell renewal and regeneration, and relieving skin allergy and eczema; oleic acid is well known as Omega-9 and has a strong moisturizing effect; linolenic acid is known as Omega-3, can keep skin moisture and healthy in a balanced manner, helps eliminate wrinkles and fine lines, and ensures that extended surface is gradually loosened, and a series of skin problems such as rough skin, heel chap, eczema, psoriasis and the like can be caused if Omega-3 is not used, so that the sunflower seed oil can not only moisten but also relieve the skin, and cannot cause acne, and is quick and mild in absorption.

The calendula oil is a calendula extract, has the effects of sterilizing, astringing wounds, treating inflammation, pimples, large pores and the like, can also calm the skin, improve sensitive skin, moisten dry lips and promote new aging, and particularly has a high moistening effect on dry skin.

The melaleuca alternifolia leaf oil is extracted from tea, has strong transdermal penetration promoting effect, can help absorption of other effective components, and can diminish inflammation and sterilize.

The 7 natural plants are combined together to play the maximum effect, have stronger anti-inflammatory effect and can strengthen the skin barrier through immunoregulation and relieving.

The raw materials are all commercially available raw materials, and are mild in nature and free of irritation.

The ointment-shaped baby hip-protecting cream has the following advantages and beneficial technical effects:

1) through experimental research, the invention finds that the optimal compatibility is obtained in reasonable selection aiming at the heavy selection of the vegetable oil, the vegetable fat, the mixed wax and the plant extraction essence, the manufactured hip-care cream has mild and non-irritant properties, can moisten and soften skin, can isolate the urine immersion in the paper diaper from the friction of the skin of a baby, can diminish inflammation and relieve itching, repairs the damaged skin and comprehensively cares the delicate skin of the baby.

2) Through deep experimental study, the mild raw materials are elaborately selected and reasonably matched to prepare the mild hip-protecting cream which does not contain mineral oil petrolatum, talcum powder, artificial essence and pigment, the hip-protecting cream is warm in nature and free of stimulation, the urine dipping in the paper diaper can be isolated from the friction of the skin of a baby, the effects of bacteriostasis and diminishing inflammation are achieved, the damaged skin is repaired, and the delicate skin of the baby is comprehensively cared.

Detailed Description

The invention discloses ointment-shaped baby hip protecting cream and a preparation method thereof, and relates to the technical field of cosmetics. The hip-protecting cream is mainly prepared from mixed wax, vegetable oil, vegetable fat, plant extraction essence and an antioxidant, is ointment-shaped, is mild and non-irritant, can isolate the skin of a baby from a paper diaper, avoids friction damage to the delicate skin of the baby, and has the effects of bacteriostasis, inflammation diminishing and relieving.

Through deep experimental study, the mild raw materials are elaborately selected and reasonably matched to prepare the mild hip care cream which does not contain mineral oil petrolatum, talcum powder, artificial essence and pigment, the hip care cream is warm in ground and has no stimulation, the urine in the paper diaper can be isolated from rubbing with the skin of a baby, the effects of bacteriostasis and diminishing inflammation are achieved, the damaged skin is repaired, and the delicate skin of the baby is comprehensively cared.

The present invention will be described in more detail with reference to the following examples and effect test examples, but the present invention is not limited to the following examples, and the percentage contents in the following examples are all in weight percent.

Example 1

An ointment-like baby hip-protecting cream comprises the following components:

sweet almond oil 38.620%, olive fruit oil 30.000%, shea butter 5.000%, grape seed oil 7.000%, beeswax 10.000%, sunflower seed wax 5.000%, candelilla wax 3.000%, lavender oil 0.005%, avocado oil 0.500%, vitamin E0.2500%, sunflower seed oil 0.010%, calendula oil 0.010%, melaleuca alternifolia leaf oil 0.100%, chamomile leaf extract/glycyrrhiza glabra root extract/centella asiatica extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/polygonum cuspidatum root extract 0.500%.

The preparation method of the ointment-shaped hip protection cream for babies comprises the following steps:

1) weighing wax: such as beeswax, candelilla wax, and sunflower seed wax, mixing the waxes, heating to 80-85 deg.C, melting, stirring to completely melt, and making into mixed wax;

2) and weighing vegetable oil: heating olive fruit oil, grape seed oil and sweet almond oil to about 70-80 deg.C, stirring to completely dissolve, and making into mixed vegetable oil;

3) adding the mixed vegetable oil obtained in the step 2) into the mixed wax obtained in the step 1), and keeping the temperature at 70-80 ℃ until the mixed vegetable oil is uniformly stirred and dissolved;

4) adding shea butter, and keeping the temperature at 70-80 deg.C until uniformly dissolved;

5) after cooling to a suitable temperature, the antioxidant vitamin E and the plant extracts were added: lavender oil, avocado oil, sunflower seed oil, calendula oil, melaleuca alternifolia leaf oil, chamomile leaf extract/glycyrrhiza glabra root extract/centella asiatica extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/polygonum cuspidatum root extract and the like, and continuously stirring and dissolving uniformly;

6) filling into a packaging material, and cooling to obtain the required baby hip-protecting cream.

The mild hip-protecting cream prepared by the embodiment is light yellow in appearance, uniform in color and good in spreadability. The ointment looks like cream, touches the skin feel characteristic of cream, does not have the characteristic that the ointment is hard to touch and is not easy to smear, does not have the characteristic that the cream is not isolated from water after being smeared, and is very convenient to use. The hip-protecting cream disclosed by the invention is good in stability, appropriate in viscosity, mild and non-irritant in texture, capable of moistening and softening skin, capable of isolating the friction between urine impregnation in a paper diaper and the skin of a baby, and capable of inhibiting bacteria, diminishing inflammation and relieving, repairing damaged skin and comprehensively caring delicate skin of the baby.

Example 2

An ointment-like baby hip-protecting cream comprises the following components:

sweet almond oil 37.700%, olive fruit oil 27.000%, shea butter 7.000%, grape seed oil 7.000%, beeswax 7.000%, sunflower seed wax 7.000%, candelilla wax 4.000%, lavender oil 0.020%, avocado oil 0.650%, vitamin E0.7500%, sunflower seed oil 0.090%, calendula oil 0.030%, melaleuca alternifolia leaf oil 0.200%, chamomile leaf extract/glycyrrhiza glabra root extract/centella asiatica extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/polygonum cuspidatum root extract 1.500%.

The hip-care cream of this example was prepared in the same manner as in example 1 above.

Example 3

An ointment-like baby hip-protecting cream comprises the following components:

sweet almond oil 30.420%, olive fruit oil 25.000%, shea butter 10.000%, grape seed oil 7.000%, beeswax 5.000%, sunflower seed wax 10.000%, candelilla wax 5.000%, lavender oil 0.050%, avocado oil 0.800%, vitamin E1.500%, sunflower seed oil 0.180%, calendula oil 0.050%, melaleuca alternifolia leaf oil 0.400%, chamomile leaf extract/glycyrrhiza glabra root extract/centella asiatica extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/polygonum cuspidatum root extract 4.500%.

This example is the same as example 1 above, but a method of preparing an ointment for protecting the buttocks of a baby.

Comparative example 1

A hip-care cream comprises the following components:

water is added to the components of hundreds of centella, zinc oxide 5.000%, propylene glycol 5.000%, isopropyl palmitate 4.000%, sunflower seed oil 2.000%, glycerin 5.000%, beeswax 5.000%, magnesium stearate 1.000%, calendula extract 0.080%, a proper amount of emulsifier, a proper amount of preservative sodium benzoate and sorbic acid, and a proper amount of daily essence.

The preparation method of the hip-protecting cream comprises the following steps:

1) grinding isopropyl palmitate and zinc oxide by a grinder for 2-3 times according to a certain proportion for later use;

2) adding sunflower seed oil and Cera flava into oil phase pan, heating to 85 deg.C, dissolving most of them, stirring until they are completely dissolved;

3) adding water, glycerol, propylene glycol and emulsifier into a main pot, uniformly dispersing, heating to 85 ℃ while stirring, and preserving heat for 10 minutes;

4) putting the 2) to be used into a main pot, homogenizing for 6 minutes, adding the 1) to be used and magnesium stearate, homogenizing for 5 minutes, keeping for 15 minutes, and cooling to 45 ℃;

5) adding antiseptic treated with water, and adding herba Sidae Rhombifoliae extract and daily essence, stirring and mixing;

6) filling into a packaging material, and cooling to obtain the needed hip-protecting cream.

Examples of Effect test

Safety testing of the examples: 1. multiple skin irritation tests:

materials and methods:

the test substance: the hip-care cream prepared in example 3 of the present invention.

Animal and feeding environment:

4 common-grade New Zealand white rabbits with the weight of 2.17 kg-2.43 kg are provided by a Dongxin laboratory animal farm of Huadu province in Guangzhou city, the feed is provided by a Guangdong province medical laboratory animal center, the animals are fed in a single cage in an animal room of the farm after being purchased, and the animal room is used after the quarantine is qualified, and the temperature of the animal room is as follows: 18 ℃ to 26 ℃, relative humidity: 40 to 70 percent.

The test method comprises the following steps:

the two sides of the spine of the back of the rabbit are cut off 24 hours before the test, the skin surface is not damaged in the cutting process, and the hair removal range is 3cm multiplied by 3cm respectively.

The test substance 0.5mL is applied to one side of skin with an area of 2.5cm × 2.5cm, and the other side is applied for 14 days without treatment, 1 time per day. The hair is sheared and the residual test substance is removed by pure water from the next day before each smearing. The results were observed after one hour and scored according to skin irritation/corrosion test table 1 of the technical specifications for cosmetic safety (2015 edition), with the control and test areas treated the same.

And (4) evaluating the results:

the average daily integral of each rabbit was calculated according to the following formula, according to the technical Specification for cosmetic safety (2015 year edition)

Skin irritation/corrosivity test table 2 rabbit skin irritation intensity was determined and other toxic effects besides irritation were observed.

Average per animal per day ═ Σ integration of erythema and edema/number of animals tested)/14:

TABLE 1 repeated skin irritation tests of test substances on rabbits

Table 2 skin irritation intensity grading

Integral mean value	Strength of
		0－＜0.5	Has no irritation
0.5－＜2.0	Slight irritation
		2.0－＜6.0	Middle irritation
6.0－＜8.0	Strong stimulation

According to the two tables 1-2, the hip-care cream provided by the invention has no stimulation to multiple skin irritations of rabbits, and the hip-care cream is mild.

2. And (3) effect testing:

test of hip protection for babies:

clinical subject efficacy assessment:

selecting double-blind, random and contrast research test; infants with the age of 0-3 years are selected as the subjects, 24 persons are selected, all volunteers are healthy infants, the hip care cream prepared in the embodiment 1 and the hip care cream prepared in the control example are used as placebo, and the baby diaper is smeared for 1 month continuously for no more than 4 times a day when changing diapers each time.

The using part: the hip pads of the control example were applied to the left hip area, and the hip pads of example 1 were applied to the right hip area.

Frequency of use: the diaper is changed after the baby urinates for 4 hours every time, and the record is observed every day.

The evaluation method comprises the following steps: the test result is scored by 5 points, and the test result is best if no red spots appear and red wind is 5 points; 2-3 red spots appear, and the score is 3, and the score is medium; the most bad ones are more red spots and 0 point of itching.

The evaluation results are shown in Table 3.

TABLE 3 clinical Subjects efficacy assessment

Thus, the results of comparing comparative example 1 with examples 1 to 3 show that the present examples 1 to 3 are superior to comparative example 1 in the effect of using urine and can effectively isolate urine to prevent red fart.

In conclusion, the hip protection cream prepared by the invention has mild and non-irritant texture, can moisten and soften skin, can isolate the friction between urine impregnation in a paper diaper and the skin of a baby, has the effects of bacteriostasis and anti-inflammation relief, repairs damaged skin, comprehensively cares the delicate skin of the baby, and is very suitable for the baby to nurse the hip.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.

Claims

1. The ointment-shaped baby hip-protecting cream is characterized by comprising the following components in percentage by weight:

2. The ointment-like baby hip-care cream according to claim 1, which is composed of the following components in percentage by weight:

3. The ointment-like baby hip-care cream according to claim 2, which is composed of the following components in percentage by weight:

4. A method for preparing the ointment-like baby hip-care cream according to any one of claims 1 to 3, comprising the steps of:

1) weighing wax: such as beeswax, candelilla wax, and sunflower seed wax, mixing the waxes, heating to 85-90 deg.C, melting, stirring to completely melt, and making into mixed wax;

2) and weighing vegetable oil: heating olive fruit oil, grape seed oil and sweet almond oil to 80-85 deg.C, stirring to dissolve completely, and making into mixed vegetable oil;

3) adding the mixed vegetable oil obtained in the step 2) into the mixed wax obtained in the step 1), and keeping the temperature at 80-85 ℃ until the mixed vegetable oil is uniformly stirred and dissolved;

4) adding shea butter, and keeping the temperature at 75-80 deg.C until uniformly dissolved;

5) after cooling to a suitable temperature, the antioxidant vitamin E and the plant extracts were added: lavender oil, avocado oil, sunflower seed oil, calendula oil, melaleuca alternifolia leaf oil, chamomile leaf extract/glycyrrhiza glabra root extract/centella asiatica extract/rosemary leaf extract/scutellaria baicalensis root extract/tea leaf extract/polygonum cuspidatum root extract, and continuously stirring and dissolving uniformly;

6) filling into packing material, and cooling to obtain the required product.