CN108743474A - A kind of ointment shape baby's diaper ointment and preparation method thereof - Google Patents

A kind of ointment shape baby's diaper ointment and preparation method thereof Download PDF

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CN108743474A
CN108743474A CN201810686394.9A CN201810686394A CN108743474A CN 108743474 A CN108743474 A CN 108743474A CN 201810686394 A CN201810686394 A CN 201810686394A CN 108743474 A CN108743474 A CN 108743474A
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oil
extract
ointment
wax
diaper
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CN108743474B (en
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林雪萍
李雪竹
陈晓朋
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Guangzhou Ao Xiya Industrial Co Ltd
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Guangzhou Ao Xiya Industrial Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • A61K2800/31Anhydrous

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Abstract

The invention discloses a kind of ointment shape baby's diaper ointments and preparation method thereof, are related to daily technical field of skin care.Baby's diaper ointment is mainly made by mixing wax class, vegetable oil, vegetable butter, plant extraction essence, antioxidant, includes specifically component:5.000-20.000% mixes wax class, 7.000-70.000% vegetable oil, 5.000-10.000% vegetable butters, 0.001-7.000% plant extractions essence, 0.25-1.500% antioxidants.The present invention is a kind of pasta baby's diaper ointment of oil, mild non-stimulated, both baby's skin can be made to keep apart with paper diaper, the skin for avoiding frictionally damage baby delicate, and has antibacterial, anti-inflammatory to alleviate effect.

Description

A kind of ointment shape baby's diaper ointment and preparation method thereof
Technical field
The present invention relates to a kind of baby's diaper ointments, belong to household chemicals technical field, and in particular to a kind of ointment shape is precious Precious diaper ointment and preparation method thereof.
Background technology
Widely available with paper diaper, the skin problem that more and more ewborn infants occur because using paper diaper is got over Come more.It is the problem of annoying many precious father treasured mothers as the red hip problem of baby.The very delicate sensitivity of the skin of baby, It is wearing airtight and paper diaper is used for a long time, because of urine insult, the skin for the baby that usually rubs easily causes the paper diaper of moistening Germ causes to be easy to red hip, or even play diaper rash, these red spots, Chang Rangying in skin surface mass propagation Youngsters itch uncomfortable very much, some are serious also to cause skin erosion, breakage.
In consideration of it, occurring the largely research about infant's diaper ointment in the prior art.But most of shield on the market Stern cream is all the frost or ointment of emulsification system, and these diaper ointments generally by chemicals grease, zinc oxide, talcum powder, essence, The compositions such as water, emulsifier, preservative, moisturizer.
Purpose using these diaper ointments is to form isolation protection film, " the red hip " of the baby that releives in skin surface The appearance of phenomenon, but its effect that damaged skin for " diaper rash " symptom occurred is not releived and repaired, all the better Add stimulation, the preservative added by the microorganism growth in these recipes in order to prevent water has certain irritation.
Moisturizer added for moisturizing such as glycerine, 1,3-BDO etc., these moisturizing dosage additive amounts great Yi rise Heat is to more stimulate skin etc..
Invention content
In order to overcome existing technical disadvantages, the object of the present invention is to provide a kind of pasta baby's diaper ointments of oil, mildly It is non-stimulated, both baby's skin can be made to keep apart with paper diaper, the skin for avoiding frictionally damage baby delicate, and have antibacterial, anti-inflammatory Alleviate effect.
It is mild stingless it is a further object of the present invention to provide a kind of preparation method of the above-mentioned pasta baby's diaper ointment of oil Swash, both baby's skin can be made to keep apart with paper diaper, the skin for avoiding frictionally damage baby delicate, and there is antibacterial, anti-inflammatory to alleviate Effect.
The technical purpose of the present invention is achieved through the following technical solutions.
A kind of ointment shape baby's diaper ointment of the present invention is made of following raw material:
5.000-20.000% mix wax class, 7.000-70.000% vegetable oil, 5.000-10.000% vegetable butters, 0.001-7.000% plant extractions essence, 0.25-1.500% antioxidants.
Furthermore, ointment shape baby's diaper ointment of the invention is made of following raw material:
The wooden fruit fat 5.000%- of Sweet Almond Oil 2.000%-40.000%, olive oil 5.000%-30.000%, breast 10.000%, grape seed oil 1.000%-7.000%, beeswax 3.000%-10.000%, sunflower seeds wax 2.000%- 10.000%, candelila wax 1.000%-5.000%, lavender oil 0.001%-0.050%, avocado oil 0.100%- 0.800%, vitamin e 0.2500%-1.500%, sunflower seed oil 0.005%-0.200%, pot marigold oil 0.005%- 0.050%, Melaleuca alternifolia leaf oil 0.010%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/centella Extract/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 0.100%-5.000%.
The said components are preferably:
The wooden fruit fat 7.000%- of Sweet Almond Oil 9.000%-40.000%, olive oil 10.000%-30.000%, breast 10.000%, grape seed oil 5.000%-7.000%, beeswax 5.000%-10.000%, sunflower seeds wax 5.000%- 10.000%, candelila wax 3.000%-5.000%, lavender oil 0.005%-0.050%, avocado oil 0.500%- 0.800%, vitamin e 0.5000%-1.500%, sunflower seed oil 0.010%-0.200%, pot marigold oil 0.010%- 0.050%, Melaleuca alternifolia leaf oil 0.100%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/centella Extract/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 0.500%-5.000%.
The said components can be more preferably:
The wooden fruit fat of Sweet Almond Oil 15.000%-40.000%, olive oil 20.000%-30.000%, breast 7.000%-10.000%, grape seed oil 5.000%-7.000%, beeswax 7.000%-10.000%, sunflower seeds wax 7.000%-10.000%, candelila wax 3.000%-5.000%, lavender oil 0.010%-0.050%, avocado oil 0.500%-0.800%, vitamin e 0.7000%-1.500%, sunflower seed oil 0.090%-0.200%, pot marigold oil 0.010%-0.050%, Melaleuca alternifolia leaf oil 0.20%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/ Gotu Kola P.E/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 1.500%- 5.000%.
Furthermore, the Sweet Almond Oil is wide is used for skin care, helps to give skin elasticity and flexibility, apply No greasy feeling is smeared, is lubricated very much, moisture can be prevented excessively to be lost by epidermis, its content of vitamin E is higher, can protect thin After birth, its fusing point is relatively low, and cold climate stability inferior is good, can keep transparent, and be unlikely to deteriorate, to skin-safe, Bu Huiyin Play acute (primary) stimulation and allergy.
Fruit of the olive oil from greenery olive, it is less containing linoleic acid, therefore its his more other liquid oil Fat is not oxidizable, is commonly applied to skin cream, anti-wrinkle cream, massage oil etc., it is identical as general vegetable oil to the permeability of skin, compared with Dormant oil is good, to skin-safe, will not cause acute (primary) skin irritatin and allergy.
The wooden fruit fat of breast has the splendid soft and moist humectant properties of moisturizing, has effects that natural activity, contains triterpene enester Class can effectively antagonize inflammation, UV damages and skin problem, protection collagen, anti-aging caused by environment while also can Promote the generation of collagen.
The light green or flaxen grape that the grape seed oil generates from bottle-green Grape Seed Extract after refined Seed oil, it is the ideal base oil of other active constituents and a kind of health-care edible oil, therefore is well known, it, which has, grows Support moisturizing, soft skin, it is anti-oxidant, lighten the stain, bactericidal antiphlogistic the effect of.
The beeswax has the function of excellent nourishing moisturizing, repairs damage, has effectively cured lip decortication phenomenon, bee Wax can absorb the oxygen-cent red radical that can cause skin oxidative, have anti-oxidant and antibacterial anti-inflammatory activity.Beeswax will not draw skin Adverse reaction is played, acute (primary) each allergy of sexual stimulus will not be caused.
The sunflower seeds wax is handled by special hardening and purifying process, as sunflower oil it is completely hydrogenated obtained by It arrives, it is the vegetable fat of sheet, has high-melting-point and fabulous stability, good with the compatibility of various waxes, has sunflower The advantage of seed oil, can make the substitute of microwax.
The avocado oil is derived from the pulp of avocado, and dry fruit meat oil-containing mass fraction is 40-80%, is in natural green, Be widely used in cosmetics keeps skin smooth as lubricant, it is stronger to the permeability of skin, and active material is contributed to transmit Enter in skin, it is also possible to deal with skin trauma and treatment skin disease, it does not have ill-effect to skin, will not cause acute (primary) stimulation and allergy, it is faster than the permeability of Sweet Almond Oil, olive oil.
Its core effect of the vitamin e is its strong anti-oxidation, can be captured since UV irradiations and environmental pollution generate Free radical, prevent the lipid peroxidation of cell or tissue, can also prevent sunburn cell formation, improve the pliability of skin, The moisturizing degree of skin is improved, scytitis is reduced, is the most important protection type vitamin of skin.
The sunflower seed oil contains abundant oleic acid, linoleic acid, leukotrienes, and linoleic acid is synthesized by organism, and is The constituent of cell membrane, this makes it have moisturizing, promotes cell turnover and regenerated property, soothes the skin allergy and eczema Disease;Oleic acid is the Omega-9 known to us, has very strong moistening effect;Leukotrienes is exactly the Omega- known to us 3, skin equilibrium moisturizing can be enabled and kept fit, help smoothes away wrinkles and microgroove, and Cobalt is real gradually in the skin of relaxation, such as lacks Omega-3 can then cause a series of skin problem, such as the cracking of pachylosis, heel, eczema, psoriasis, thus to day Seed oil of sunflower can not only moisten, and can also releive skin, and will not cause acne, absorb soon, mildly.
The pot marigold oil is pot marigold extract, has and sterilizes, convergence wound, improvement inflammation, dark sore, and pore is coarse etc. Problem, can also calm skin, improve sensibility skin quality, while can also moisten dry lip, promote metabolism, especially For dry skin, there is the moisturizing effect of height.
The Melaleuca alternifolia leaf oil is extracted from tealeaves, there is very strong transdermal penetration facilitation, can be helped The absorption of other active ingredients, and can anti-inflammation and sterilization.
The german chamomile leaf extract/glycyrrhiza glabra root extract/Gotu Kola P.E/rosemary leaf extract/scutellariae,radix Extract/tea extract/giant knotweed root extract, this 7 kinds of natural plants, which are combined, can play maximum effect, have compared with Strong anti-inflammatory effect can pass through immunological regulation and reinforcement skin barrier of releiving.
Above-mentioned raw material used is marketable material, and property is mild, non-stimulated.
Ointment shape baby's diaper ointment of the present invention has the following advantages that and beneficial technique effect:
1) it is found by experimental study, for the heavy selection of vegetable oil, vegetable butter, blended wax, plant extraction essence, originally Invention obtains best compatibility in rational selection, and the diaper ointment property made was not only mild non-stimulated, but also can moisten Soft skin can also be isolated the friction of urine insult and baby's skin in paper diaper, and can be damaged flesh with anti-inflammatory anti-itch, maintenance Skin, the skin for keeping baby delicate are comprehensively takeed good care of.
2) present invention passes through deep experimental study, selects mild raw material meticulously, reasonably combined, is fabricated to one kind and is free of Dormant oil vaseline, without talcum powder, not water content, the mild diaper ointment without artificial essence, without pigment, this diaper ointment quality temperature With it is non-stimulated, the friction of urine insult and baby's skin in paper diaper can not only be isolated, but also have the effect of antibacterial, anti-inflammatory is alleviated, Maintenance is damaged skin, and the skin for keeping baby delicate is comprehensively takeed good care of.
Specific implementation mode
The invention discloses a kind of ointment shape baby diaper ointment diaper ointments and preparation method thereof, are related to cosmetic art neck Domain.The diaper ointment is mainly made by mixing wax class, vegetable oil, vegetable butter, plant extraction essence, antioxidant, it is A kind of pasta diaper ointment of oil, it is mild non-stimulated, both baby's skin can be made to keep apart with paper diaper, and avoid frictionally damage baby tender Tender skin, and there is antibacterial, anti-inflammatory to alleviate effect.
The present invention passes through deep experimental study, selects mild raw material meticulously, reasonably combined, is fabricated to a kind of without mine Oil field fat, without talcum powder, not water content, the mild diaper ointment without artificial essence, without pigment, this diaper ointment quality temperature With it is non-stimulated, the friction of urine insult and baby's skin in paper diaper can not only be isolated, but also have the effect of antibacterial, anti-inflammatory is alleviated, Maintenance is damaged skin, and the skin for keeping baby delicate is comprehensively takeed good care of.
Below by way of specific embodiment combination effete test embodiment to being described in further detail, but the present invention is not limited in Embodiment below, degree in following embodiment weight percent meter.
Embodiment 1
A kind of ointment shape baby's diaper ointment includes following components:
The wooden fruit fat 5.000% of Sweet Almond Oil 38.620%, olive oil 30.000%, breast, grape seed oil 7.000%, Beeswax 10.000%, sunflower seeds wax 5.000%, candelila wax 3.000%, lavender oil 0.005%, avocado oil 0.500%, dimension He orders E 0.2500%, sunflower seed oil 0.010%, pot marigold oil 0.010%, Melaleuca alternifolia leaf oil 0.100%, german chamomile Leaf extract/glycyrrhiza glabra root extract/Gotu Kola P.E/rosemary leaf extract/radix scutellariae root extract/tealeaves extraction Object/giant knotweed root extract 0.500%.
A kind of preparation method of ointment shape baby's diaper ointment of the present embodiment includes the following steps:
1) wax class is first weighed:Such as beeswax, candelila wax, sunflower seeds waxes, these waxes are mixed and are heated to 80-85 DEG C, Stirring is opened after slush to dissolving completely, and it is for use that blended wax is made;
2) vegetable oil is weighed again:Olive oil, grape seed oil, Sweet Almond Oil are heated to 70-80 DEG C or so, and stirring is extremely It dissolves completely, it is for use that mixed vegetable oil is made;
3) mixed vegetable oil of step 2) is added to the blended wax of step 1), temperature is maintained at 70-80 DEG C, until stirring It is uniformly dissolved;
4) the wooden fruit fat of breast is added, temperature is maintained at 70-80 DEG C, until stirring and dissolving is uniform;
5) after being down to suitable temperature, antioxidant vitamin e and plant extraction essence is added:Lavender oil, avocado oil, to Day seed oil of sunflower, pot marigold oil, Melaleuca alternifolia leaf oil, german chamomile leaf extract/glycyrrhiza glabra root extract/centella extraction It is uniform to continue stirring and dissolving for object/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract etc.;
6) it is filled to packaging material, up to required baby's diaper ointment after cooling.
Mild diaper ointment appearance made by the present embodiment is in light yellow, and color is uniform, and stretchability is good.Cream is seemed, is touched Like the skin sense speciality of frost, without the harder characteristic not easy to apply of ointment sense of touch, nonwatertight characteristic after also being smeared without frost makes It uses easily.The diaper ointment stability of the present invention is good, and viscosity is suitable, and quality was not only mild non-stimulated, but also can moisten softness Skin, can also be isolated the friction of urine insult and baby's skin in paper diaper, and have the effect of antibacterial, anti-inflammatory is alleviated, maintenance Impaired skin, the skin for keeping baby delicate are comprehensively takeed good care of.
Embodiment 2
A kind of ointment shape baby's diaper ointment includes following components:
The wooden fruit fat 7.000% of Sweet Almond Oil 37.700%, olive oil 27.000%, breast, grape seed oil 7.000%, Beeswax 7.000%, sunflower seeds wax 7.000%, candelila wax 4.000%, lavender oil 0.020%, avocado oil 0.650%, dimension He orders E 0.7500%, sunflower seed oil 0.090%, pot marigold oil 0.030%, Melaleuca alternifolia leaf oil 0.200%, german chamomile Leaf extract/glycyrrhiza glabra root extract/Gotu Kola P.E/rosemary leaf extract/radix scutellariae root extract/tealeaves extraction Object/giant knotweed root extract 1.500%.
A kind of preparation method of diaper ointment of the present embodiment is the same as above-described embodiment 1.
Embodiment 3
A kind of ointment shape baby's diaper ointment includes following components:
The wooden fruit fat 10.000% of Sweet Almond Oil 30.420%, olive oil 25.000%, breast, grape seed oil 7.000%, Beeswax 5.000%, sunflower seeds wax 10.000%, candelila wax 5.000%, lavender oil 0.050%, avocado oil 0.800%, dimension He orders E 1.500%, sunflower seed oil 0.180%, pot marigold oil 0.050%, Melaleuca alternifolia leaf oil 0.400%, german chamomile Leaf extract/glycyrrhiza glabra root extract/Gotu Kola P.E/rosemary leaf extract/radix scutellariae root extract/tealeaves extraction Object/giant knotweed root extract 4.500%.
A kind of preparation method of ointment shape baby's diaper ointment of the present embodiment is the same as above-described embodiment 1.
Reference examples 1
A kind of diaper ointment includes following components:
Water be added to very, zinc oxide 5.000%, propylene glycol 5.000%, isopropyl palmitate 4.000%, sunflower Seed oil 2.000%, glycerine 5.000%, beeswax 5.000%, magnesium stearate 1.000%, pot marigold extract 0.080%, emulsification Appropriate agent, preservative sodium benzoate and proper amount of sorbic acid, appropriate daily essence.
The preparation method of above-mentioned diaper ointment is as follows:
1) for use after grinding isopropyl palmitate and zinc oxide 2-3 times with grinder according to a certain percentage;
2) sunflower seed oil, beeswax are added in oil phase pot and are heated to 85 DEG C, stirring is opened after largely dissolving, until completely Dissolving, for use;
3) water, glycerine, propylene glycol, emulsifier are added in main cooker, are allowed to be uniformly dispersed, are heated to 85 DEG C while stirring, Heat preservation 10 minutes;
4) by for use 2) it puts into main cooker, for use 1 is added in homogeneous 6 minutes) and magnesium stearate, homogeneous 5 minutes, guarantor 45 DEG C are cooled to after 15 minutes;
5) with the good preservative of water process and pot marigold extract, daily essence is added in advance in addition, until being stirred Uniformly;
6) it is filled to packaging material, up to required diaper ointment after cooling.
Effete test embodiment
To embodiment security test:1, multiple skin irritation test:
Material and method:
Tested material:Diaper ointment made by the embodiment of the present invention 3.
Animal and feeding environment:
Regular grade New Zealand White rabbit 4, weight 2.17kg~2.43kg, by the experiment of Guangzhou Huadu District China of flower Eastcom Animal-breeding field provides, and feed is provided by Guangdong Medical Lab Animal Center, and animal is raised after buying in the court's animal house single cage It supports, is used after quarantine is qualified, animal house temperature:18 DEG C~26 DEG C, relative humidity:40%~70%.
Test method:
About family's rabbit back backbone both sides hair is cut for 24 hours before experiment, skin surface is not damaged in cropping, unhairing range is each For 3cm × 3cm.
Tested material 0.5mL is taken to be applied on the skin of side, application area 2.5cm × 2.5cm, the other side does not deal with conduct Control smears 1 time, continuously smears 14d daily.Since second day, it is tested to remove residual with pure water for cropping before smearing every time Object.Observation is as a result, press after one hour《Cosmetics safety technical specification》Skin irritation/corrosion test the table of (version in 2015) 1 scoring, check plot and trial zone are equally handled.
Evaluation of result:
Daily every rabbit average integral is calculated according to the following formula, presses《Cosmetics safety technical specification》(version in 2015)
Skin irritation/corrosion test table 2 judge rabbit skin irritatin intensity, and observe its in addition to irritation His toxic effect.
Daily every animal average integral=(∑ erythema and oedema integral/animal subject number)/14:
1 tested material of table is to the multiple skin irritation test of rabbit
2 skin irritatin strength grading of table
Integral mean value Intensity
0- < 0.5 It is non-stimulated
0.5- < 2.0 Minimal irritation
2.0- < 6.0 Moderate stimulation
6.0- < 8.0 Strong stimulation
Can be seen that diaper ointment provided by the invention according to two table 1-2 is stingless to the multiple skin irritation of rabbit Swash, shows that this diaper ointment is milder.
2, measure of merit:
The protection test of baby's buttocks:
Clinical trial subjects measures of effectiveness:
Select double blind, random, comparative study test;Baby of the subject age at 0-3 Sui, 24 people of selection, volunteer are Healthy baby is virgin, makees placebo using diaper ointment made of diaper ointment made of embodiment 1 and reference examples, when each baby changes urine pants It smears, is no more than 4 times, continuous 1 month within one day.
Use position:The diaper ointment of reference examples is applied to left stern region, and the hip pad of embodiment 1 is applied to right stern region.
Frequency of use:Each baby urinates urine and just changes urine pants after 4 hours, observes and records daily.
Evaluating method:Test result is made to score with 5 points, and it is 5 points punctation, red wind wind do not occur then, is It is best;There is punctation 2-3, is then 3 points, in being;It is then 0 point that appearance punctation is more, trace is itched, and is worst.
Its assessment result is as shown in table 3.
3 clinical trial subjects measures of effectiveness of table
Thus the reference examples 1 and embodiment 1-3 results compared can obtain, the using effect of the present embodiment 1-3 better than pair As usual 1, and urine can be effectively isolated and prevent red wind wind phenomenon.
It, can also be every in conclusion diaper ointment quality made by the present invention was not only mild non-stimulated, but also can moisten softness skin Friction from urine insult and baby's skin in paper diaper, and have the effect of antibacterial, anti-inflammatory is alleviated, maintenance is damaged skin, makes The delicate skin of baby is comprehensively takeed good care of, and is very suitable for babies and is nursed buttocks use.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore It is every without departing from technical solution of the present invention content, simply repaiied to any made by above example according to the technical essence of the invention Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.

Claims (10)

1. a kind of ointment shape baby's diaper ointment, it is characterised in that:By weight percentage, containing following components:
5.000-20.000% mixes wax class, 7.000-70.000% vegetable oil, 5.000-10.000% vegetable butters, 0.001- 7.000% plant extraction essence, 0.25-1.500% antioxidants.
2. ointment shape baby's diaper ointment according to claim 1, it is characterised in that:The mixing wax class can be beeswax, Arbitrary two kinds or more in candelila wax, Brazil wax, sunflower seeds wax, microwax, ceresine, poly- second wax, synthetic wax are a variety of Mixture, the usage amount of the blended wax is 5.000-20.000%.
3. ointment shape baby's diaper ointment according to claim 1, it is characterised in that:The vegetable oil can be olea europaea fruit The mixture that arbitrary two kinds or more several of oil, macadimia nut oil, grape seed oil, coconut oil, Sweet Almond Oil, jojoba seed oil, The usage amount of the vegetable oil is 7.000-70.000%.
4. ointment shape baby's diaper ointment according to claim 1, it is characterised in that:The vegetable butter can be the wooden fruit of breast Fat, aloe resin, great Hua cocoa butters, mother-in-law sieve's fat any one or two or more mixtures, the usage amount of the vegetable butter are 5.000-10.000%.
5. ointment shape baby's diaper ointment according to claim 1, it is characterised in that:The plant extraction essence can be to smoke Clothing grass oil, avocado oil, sunflower seed oil, pot marigold oil, oat kernel oil, Melaleuca alternifolia leaf oil, german chamomile extract/light fruit are sweet In grass roots extract/Gotu Kola P.E/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract The usage amount of arbitrary two kinds or more several mixtures, the plant extraction essence is 0.001-7.000%.
6. ointment shape baby's diaper ointment according to claim 1, it is characterised in that:The antioxidant can be vitamin E, one kind in butylated hydroxy anisole, dibutyl hydroxy toluene, Rosmarinus officinalis extract, ascorbic acid and its derivative etc. or its Mixture.
7. ointment shape baby's diaper ointment according to claim 1, which is characterized in that by weight percentage, containing following Component:
The wooden fruit fat 5.000%- of Sweet Almond Oil 2.000%-40.000%, olive oil 5.000%-30.000%, breast 10.000%, grape seed oil 1.000%-7.000%, beeswax 3.000%-10.000%, sunflower seeds wax 2.000%- 10.000%, candelila wax 1.000%-5.000%, lavender oil 0.001%-0.050%, avocado oil 0.100%- 0.800%, vitamin e 0.2500%-1.500%, sunflower seed oil 0.005%-0.200%, pot marigold oil 0.005%- 0.050%, Melaleuca alternifolia leaf oil 0.010%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/centella Extract/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 0.100%-5.000%.
8. ointment shape baby's diaper ointment according to claim 7, which is characterized in that by weight percentage, containing following Component:
The wooden fruit fat 7.000%- of Sweet Almond Oil 9.000%-40.000%, olive oil 10.000%-30.000%, breast 10.000%, grape seed oil 5.000%-7.000%, beeswax 5.000%-10.000%, sunflower seeds wax 5.000%- 10.000%, candelila wax 3.000%-5.000%, lavender oil 0.005%-0.050%, avocado oil 0.500%- 0.800%, vitamin e 0.5000%-1.500%, sunflower seed oil 0.010%-0.200%, pot marigold oil 0.010%- 0.050%, Melaleuca alternifolia leaf oil 0.100%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/centella Extract/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 0.500%-5.000%.
9. ointment shape baby's diaper ointment according to claim 8, which is characterized in that by weight percentage, containing following Component:
The wooden fruit fat 7.000%- of Sweet Almond Oil 15.000%-40.000%, olive oil 20.000%-30.000%, breast 10.000%, grape seed oil 5.000%-7.000%, beeswax 7.000%-10.000%, sunflower seeds wax 7.000%- 10.000%, candelila wax 3.000%-5.000%, lavender oil 0.010%-0.050%, avocado oil 0.500%- 0.800%, vitamin e 0.7000%-1.500%, sunflower seed oil 0.090%-0.200%, pot marigold oil 0.010%- 0.050%, Melaleuca alternifolia leaf oil 0.20%-0.400%, german chamomile leaf extract/glycyrrhiza glabra root extract/centella carry Take object/rosemary leaf extract/radix scutellariae root extract/tea extract/giant knotweed root extract 1.500%-5.000%.
10. the preparation method of ointment shape baby's diaper ointment described in any one of claim 1-9, which is characterized in that including with Lower step:
1) wax class is first weighed:Such as beeswax, candelila wax, sunflower seeds wax, these waxes are mixed and are heated to 85-90 DEG C, are partly melted Stirring is opened after change to dissolving completely, and it is for use that blended wax is made;
2) vegetable oil is weighed again:Olive oil, grape seed oil, Sweet Almond Oil are heated to 80-85 DEG C or so, stir to complete It dissolves, it is for use that mixed vegetable oil is made;
3) mixed vegetable oil of step 2) is added in the blended wax of step 1), temperature is maintained at 80-85 DEG C, until stirring molten Solution is uniform;
4) the wooden fruit fat of breast is added, temperature is maintained at 75-80 DEG C, until stirring and dissolving is uniform;
5) antioxidant vitamin e and plant extraction essence is added after being down to suitable temperature:Lavender oil, avocado oil, sunflower Seed oil, pot marigold oil, Melaleuca alternifolia leaf oil, german chamomile leaf extract/glycyrrhiza glabra root extract/Gotu Kola P.E/fan It is uniform to continue stirring and dissolving for repeatedly Herba Pelargonii Graveolentis extract/radix scutellariae root extract/tea extract/giant knotweed root extract etc.;
6) it is filled to packaging material, up to required product after cooling.
CN201810686394.9A 2018-06-28 2018-06-28 Ointment-shaped baby hip-protecting cream and preparation method thereof Expired - Fee Related CN108743474B (en)

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Cited By (8)

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CN109464320A (en) * 2018-11-09 2019-03-15 厦门舒菲娅化妆品有限公司 A kind of baby baths liquid and preparation method thereof
CN110934786A (en) * 2019-11-20 2020-03-31 湖北研妆实业有限公司 Production process of baby hip-protecting double-layer essence liquid
WO2020107000A1 (en) * 2018-11-21 2020-05-28 Products On The Go, LLC Certified natural skin care products
CN111228207A (en) * 2020-03-11 2020-06-05 广州市逸轩精细化工有限公司 Dampness-rash-eliminating hip-protecting cream and preparation method thereof
WO2020247980A1 (en) * 2019-06-06 2020-12-10 The Procter & Gamble Company Skin care compositions derived from renewable resources and absorbent articles comprising same
CN113057911A (en) * 2021-04-12 2021-07-02 杭州易蓬科技有限公司 Skin care composition with water resistance and antibacterial effect
WO2021218039A1 (en) * 2020-04-29 2021-11-04 上海林清轩生物科技有限公司 Biomimetic and camellia extract-containing skin barrier repair composition and application thereof
CN117064820A (en) * 2023-10-10 2023-11-17 广州科玛生物科技股份有限公司 Yolk oil-containing infant soothing cream for skin repair and preparation method thereof

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CN106266384A (en) * 2016-08-31 2017-01-04 肖涵 A kind of plant ointment preventing and treating infant diaper rash and preparation method thereof
CN106389582A (en) * 2016-08-31 2017-02-15 肖涵 Universal ointment for babies and preparation method of universal ointment
CN107625703A (en) * 2016-07-15 2018-01-26 黄青山 Stern protection cream of lotus positive electricity antibacterial maintenance film and preparation method thereof can be formed

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CN103385834A (en) * 2013-08-02 2013-11-13 太仓市伟基生物科技有限公司 Preparation method of baby diaper rash cream
CN107625703A (en) * 2016-07-15 2018-01-26 黄青山 Stern protection cream of lotus positive electricity antibacterial maintenance film and preparation method thereof can be formed
CN106266384A (en) * 2016-08-31 2017-01-04 肖涵 A kind of plant ointment preventing and treating infant diaper rash and preparation method thereof
CN106389582A (en) * 2016-08-31 2017-02-15 肖涵 Universal ointment for babies and preparation method of universal ointment

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109464320A (en) * 2018-11-09 2019-03-15 厦门舒菲娅化妆品有限公司 A kind of baby baths liquid and preparation method thereof
WO2020107000A1 (en) * 2018-11-21 2020-05-28 Products On The Go, LLC Certified natural skin care products
WO2020247980A1 (en) * 2019-06-06 2020-12-10 The Procter & Gamble Company Skin care compositions derived from renewable resources and absorbent articles comprising same
CN110934786A (en) * 2019-11-20 2020-03-31 湖北研妆实业有限公司 Production process of baby hip-protecting double-layer essence liquid
CN111228207A (en) * 2020-03-11 2020-06-05 广州市逸轩精细化工有限公司 Dampness-rash-eliminating hip-protecting cream and preparation method thereof
WO2021218039A1 (en) * 2020-04-29 2021-11-04 上海林清轩生物科技有限公司 Biomimetic and camellia extract-containing skin barrier repair composition and application thereof
CN113057911A (en) * 2021-04-12 2021-07-02 杭州易蓬科技有限公司 Skin care composition with water resistance and antibacterial effect
CN117064820A (en) * 2023-10-10 2023-11-17 广州科玛生物科技股份有限公司 Yolk oil-containing infant soothing cream for skin repair and preparation method thereof

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