CN108741091A - A kind of compound probiotic functional food for adjusting infantile enteritis immune response - Google Patents
A kind of compound probiotic functional food for adjusting infantile enteritis immune response Download PDFInfo
- Publication number
- CN108741091A CN108741091A CN201810991277.3A CN201810991277A CN108741091A CN 108741091 A CN108741091 A CN 108741091A CN 201810991277 A CN201810991277 A CN 201810991277A CN 108741091 A CN108741091 A CN 108741091A
- Authority
- CN
- China
- Prior art keywords
- parts
- mixing
- raw material
- compound probiotic
- immune response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006041 probiotic Substances 0.000 title claims abstract description 67
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 67
- 150000001875 compounds Chemical class 0.000 title claims abstract description 43
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 41
- 208000004232 Enteritis Diseases 0.000 title claims abstract description 34
- 235000013376 functional food Nutrition 0.000 title claims abstract description 32
- 230000028993 immune response Effects 0.000 title claims abstract description 22
- 238000002156 mixing Methods 0.000 claims abstract description 44
- 239000000203 mixture Substances 0.000 claims abstract description 43
- 239000002994 raw material Substances 0.000 claims abstract description 40
- 235000013406 prebiotics Nutrition 0.000 claims abstract description 22
- 238000009472 formulation Methods 0.000 claims abstract description 17
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 10
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 claims abstract description 9
- 241001465754 Metazoa Species 0.000 claims abstract description 9
- 229940009289 bifidobacterium lactis Drugs 0.000 claims abstract description 9
- 241000186012 Bifidobacterium breve Species 0.000 claims abstract description 8
- 240000001046 Lactobacillus acidophilus Species 0.000 claims abstract description 7
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims abstract description 7
- 241000186604 Lactobacillus reuteri Species 0.000 claims abstract description 7
- 239000004615 ingredient Substances 0.000 claims abstract description 7
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims abstract description 7
- 229940001882 lactobacillus reuteri Drugs 0.000 claims abstract description 7
- 241000186840 Lactobacillus fermentum Species 0.000 claims abstract description 6
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims abstract description 6
- 238000005303 weighing Methods 0.000 claims abstract 2
- 235000013305 food Nutrition 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- 230000036039 immunity Effects 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 description 7
- 239000000047 product Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 230000009286 beneficial effect Effects 0.000 description 4
- 230000000968 intestinal effect Effects 0.000 description 4
- 238000012856 packing Methods 0.000 description 4
- 244000005700 microbiome Species 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000186046 Actinomyces Species 0.000 description 1
- 241000193171 Clostridium butyricum Species 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 235000020167 acidified milk Nutrition 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 235000021393 food security Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000007366 host health Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/143—Fermentum
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/173—Reuteri
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/515—Animalis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/519—Breve
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/531—Lactis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of compound probiotic functional foods for adjusting infantile enteritis immune response, including bifidobacterium lactis, Lactobacillus rhamnosus, animal bifidobacteria, lactobacillus acidophilus, lactobacillus reuteri, lactobacillus fermenti, bifidobacterium breve, oligofructose and oligoisomaltose, this is used to adjust the preparation method of the compound probiotic functional food of infantile enteritis immune response, includes the following steps：Each ingredient in mixing probiotics and mixing prebiotics is sized to 80 mesh hereinafter, then being weighed according to above-mentioned mass ratio, load weighted each raw material is placed in dry-mixed machine and is uniformly mixed；Raw material after mixing carries out press sheet formulation, or pack of directly weighing.It is on the low side that the present invention solves current compound probiotic functional food flora type, and the proportioning of each flora is unbalance, it is difficult to reach the problem of adjusting infantile enteritis and body's immunity.
Description
Technical field
It is specially a kind of immune anti-for adjusting infantile enteritis the present invention relates to feature capability technical field of food preparation
The compound probiotic functional food answered.
Background technology
Probiotics is a kind of active microorganism beneficial to host, is to be colonized in human body intestinal canal, in reproductive system, can generate
Definite health efficacy so as to improve host's microecological balance, play the active beneficial microorganism general name of beneficial effect.Human body moves
Beneficial bacterium or fungi mainly have in object：Clostridium butyricum, lactobacillus, Bifidobacterium, actinomyces, saccharomycete etc..Generation at present
The most powerful product of the function of being studied in boundary be mainly the above all kinds of microorganism groups at composite reactive probiotics, extensive use
In bioengineering, industrial or agricultural, food security and life and health field.
Prebiotics are a kind of dietary supplements, pass through the growth of the bacterium in a kind of or a small number of kind of bacterium colony of stimulation of selectivity
Wholesome effect is generated so as to improve the food composition that can not be digested of host health to host with activity.It is successfully prebiotic
Member should be when passing through upper digestive tract, it is most of not to be digested and be fermented by intestinal flora.Most importantly it is
The growth of profitable strain is stimulated, rather than has potential pathogenic or corrupt active harmful bacteria.
For children in developmental process, it usually needs supplement various nutriments, but first ensure battalion needed for children's growth
While supporting substance, additionally it should be noted that the gastro-intestinal problems of children need the enteritis and body's immunity that adjust children in time,
Therefore it needs to take in corresponding compound probiotic functional food in time and be adjusted, but existing compound probiotic functionality is eaten
Product flora type is on the low side, and the proportioning of each flora is unbalance, it is difficult to have the function that adjust infantile enteritis and body's immunity.
Invention content
(1) the technical issues of solving
In view of the deficiencies of the prior art, the present invention provides a kind of for adjusting the compound prebiotic of infantile enteritis immune response
Bacterium functional food, it is on the low side to solve current compound probiotic functional food flora type, and the proportioning of each flora is unbalance,
It is difficult to reach the problem of adjusting infantile enteritis and body's immunity.
(2) technical solution
To achieve the above object, the present invention provides the following technical solutions：It is a kind of to be used to adjust infantile enteritis immune response
Compound probiotic functional food includes the composition of following mass fraction：
50-80 parts of probiotics is mixed, 20-50 parts of prebiotics are mixed.
Wherein, the mixing probiotics includes the composition of following mass fraction：15-25 parts of bifidobacterium lactis, rhamnose breast
5-10 parts of bacillus, 15-25 parts of animal bifidobacteria, 10-20 parts of lactobacillus acidophilus, 10-20 parts of lactobacillus reuteri, acidified milk bar
10-20 parts of 15-25 parts of bacterium and bifidobacterium breve.
The mixing prebiotics include the composition of following mass fraction：10-30 parts of oligofructose and oligoisomaltose 10-
20 parts.
The present invention also provides a kind of systems for adjusting the compound probiotic functional food of infantile enteritis immune response
Preparation Method includes the following steps：
(2) pretreatment of raw material：Will mixing probiotics and mixing prebiotics in each ingredient be sized to 80 mesh hereinafter, then by
It is weighed according to above-mentioned mass ratio, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, or each after mixing
Raw material is directly weighed pack.
Preferably, when the step (2) carries out raw material mixing, dry-mixed machine rotating speed is set as 100-200rpm, mixes duration
It is set as 20-40 minutes.
Preferably, when the step (3) carries out press sheet formulation, pressure value is set as 4-5KN；Mix total filling of raw material
Measure 5.0-6.0mm.
(3) advantageous effect
The present invention provides a kind of for adjusting the compound probiotic functional food of infantile enteritis immune response, have with
Lower advantageous effect：
(1) compound probiotic functional food prepared by inventive formulation, viable count can reach 121-1011CFU/
The viable count of g, traditional compound probiotic are only 106-109CFU/g；It can be seen that compound probiotic work(prepared by the present invention
Energy property food considerably increases the total viable count of probiotics, can effectively reduce probiotics and play a role the time used, to
Have the function that rapidly and efficiently to adjust infantile enteritis and body's immunity；
(2) bifidobacterium lactis in the compound probiotic for preparing of the present invention, animal bifidobacteria, bifidobacterium breve three it
Between mutually act synergistically, can in enteron aisle by induce immunogene increased response human body immune function, adjust human body intestinal canal
Flora imbalance simultaneously maintains to balance, therefore the compound probiotic can fully adjust children's vivo immunization function.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical solution in the embodiment of the present invention is clearly and completely retouched
It states, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the present invention
In embodiment, every other implementation obtained by those of ordinary skill in the art without making creative efforts
Example, shall fall within the protection scope of the present invention.
Embodiment 1
A kind of compound probiotic functional food for adjusting infantile enteritis immune response, including following mass fraction
Composition：
50 parts of probiotics is mixed, 50 parts of prebiotics are mixed.
Wherein, mixing probiotics includes the composition of following mass fraction：15 parts of bifidobacterium lactis, 5 parts of Lactobacillus rhamnosus,
15 parts of animal bifidobacteria, 10 parts of lactobacillus acidophilus, 10 parts of lactobacillus reuteri, 15 parts of lactobacillus fermenti and bifidobacterium breve
10 parts；Mixing prebiotics include the composition of following mass fraction：20 parts of 30 parts of oligofructose and oligoisomaltose.
The preparation method of the compound probiotic functional food of the adjusting infantile enteritis immune response, includes the following steps：
(1) pretreatment of raw material：Will mixing probiotics and mixing prebiotics in each ingredient be sized to 80 mesh hereinafter, then by
It is weighed according to above-mentioned mass ratio, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed, wherein dry-mixed machine rotating speed is arranged
For 100rpm, mixing duration is set as 20 minutes；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, tablet press machine model ZPW-
19B, and pressure value is set as 4KN；Mix total loading 5.0mm of raw material；Tablet food bottling packing made of tabletting, or
Each raw material after person will mix directly weighs pack to get finished product compound probiotic functional food.
Embodiment 2
A kind of compound probiotic functional food for adjusting infantile enteritis immune response, including following mass fraction
Composition：
60 parts of probiotics is mixed, 40 parts of prebiotics are mixed.
Wherein, mixing probiotics includes the composition of following mass fraction：18 parts of bifidobacterium lactis, 7 parts of Lactobacillus rhamnosus,
18 parts of animal bifidobacteria, 13 parts of lactobacillus acidophilus, 13 parts of lactobacillus reuteri, 18 parts of lactobacillus fermenti and bifidobacterium breve
13 parts；Mixing prebiotics include the composition of following mass fraction：15 parts of 25 parts of oligofructose and oligoisomaltose.
This is used to adjust the preparation method of the compound probiotic functional food of infantile enteritis immune response, including walks as follows
Suddenly：
(1) pretreatment of raw material：Will mixing probiotics and mixing prebiotics in each ingredient be sized to 80 mesh hereinafter, then by
It is weighed according to above-mentioned mass ratio, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed, wherein dry-mixed machine rotating speed is arranged
For 130rpm, mixing duration is set as 27 minutes；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, tablet press machine model ZPW-
19B, and pressure value is set as 4.3KN；Mix total loading 5.3mm of raw material；Tablet food bottling packing made of tabletting,
Or each raw material after mixing directly weighs pack to get finished product compound probiotic functional food.
Embodiment 3
A kind of compound probiotic functional food for adjusting infantile enteritis immune response, including following mass fraction
Composition：
70 parts of probiotics is mixed, 30 parts of prebiotics are mixed；
Wherein, mixing probiotics includes the composition of following mass fraction：21 parts of bifidobacterium lactis, 8 parts of Lactobacillus rhamnosus,
21 parts of animal bifidobacteria, 17 parts of lactobacillus acidophilus, 17 parts of lactobacillus reuteri, 21 parts of lactobacillus fermenti and bifidobacterium breve
17 parts；Mixing prebiotics include the composition of following mass fraction：15 parts of 15 parts of oligofructose and oligoisomaltose.
This is used to adjust the preparation method of the compound probiotic functional food of infantile enteritis immune response, including walks as follows
Suddenly：
(1) pretreatment of raw material：Will mixing probiotics and mixing prebiotics in each ingredient be sized to 80 mesh hereinafter, then by
It is weighed according to above-mentioned mass ratio, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed；Wherein, dry-mixed machine rotating speed is arranged
For 160rpm, mixing duration is set as 32 minutes；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, tablet press machine model ZPW-
19B, and pressure value is set as 4.7KN；Mix total loading 5.7mm of raw material；Tablet food bottling packing made of tabletting,
Or each raw material after mixing directly weighs pack to get finished product compound probiotic functional food.
Embodiment 4
A kind of compound probiotic functional food for adjusting infantile enteritis immune response, including following mass fraction
Composition：
80 parts of probiotics is mixed, 20 parts of prebiotics are mixed；
Wherein, mixing probiotics includes the composition of following mass fraction：25 parts of bifidobacterium lactis, Lactobacillus rhamnosus 10
Part, 25 parts of animal bifidobacteria, 20 parts of lactobacillus acidophilus, 20 parts of lactobacillus reuteri, 25 parts of lactobacillus fermenti and short bifid
20 parts of bacillus；Mixing prebiotics include the composition of following mass fraction：10 parts of 10 parts of oligofructose and oligoisomaltose.
This is used to adjust the preparation method of the compound probiotic functional food of infantile enteritis immune response, including walks as follows
Suddenly：
(1) pretreatment of raw material：Will mixing probiotics and mixing prebiotics in each ingredient be sized to 80 mesh hereinafter, then by
It is weighed according to above-mentioned mass ratio, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed；Wherein, dry-mixed machine rotating speed is arranged
For 200rpm, mixing duration is set as 40 minutes；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, tablet press machine model ZPW-
19B, and pressure value is set as 5KN；Mix total loading 6mm of raw material；Tablet food bottling packing made of tabletting, or
Each raw material after mixing directly weighs pack to get finished product compound probiotic functional food.
Compound probiotic functional food prepared by inventive formulation, viable count can reach 121-1011CFU/g, pass
The viable count of the compound probiotic of system is only 106-109CFU/g；It can be seen that compound probiotic prepared by the present invention is functional
Food considerably increases the total viable count of probiotics, can effectively reduce probiotics and play a role the time used, to reach
Rapidly and efficiently adjust the effect of infantile enteritis and body's immunity.
Infantile enteritis improvement is evaluated
Evaluation method：Select 100 people of infantile enteritis patient, each 50 people of men and women is divided into two groups, and one group is experimental group, one group
For control group, tested crowd takes compound made of embodiment 3 in the case where keeping its original life, work and rest custom etc.
Probiotics, control group do not take compound probiotic.Count and record the data of feedback.
Instructions of taking：Twice a day, once in the morning and once at night, a two panels, warm water take, and survey the situation after its use, period
For surrounding.
Evaluation criterion：Continuous 1-3 defecation daily, and it is no longer in water sample to defecate, no dehydration and heating problem are determined as intestines
Inflammation improves.
As can be seen from the table, experimental group enteritis after using one week there has been slight improvement, with Time of Administration
Extend, the problem still exists is further improved for enteritis, and until week 4 Mondays, infantile enteritis patient cures completely.
In addition, bifidobacterium lactis, animal bifidobacteria in the compound probiotic of the present invention, between bifidobacterium breve three
Mutually synergistic effect can adjust the bacterium of human body intestinal canal in enteron aisle by inducing immunogene increased response human body immune function
Group lacks of proper care and maintains to balance, therefore the compound probiotic can fully adjust children's vivo immunization function.
It should be noted that herein, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also include other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (6)
1. a kind of compound probiotic functional food for adjusting infantile enteritis immune response, which is characterized in that comprising following
The composition of mass fraction：
50-80 parts of probiotics is mixed, 20-50 parts of prebiotics are mixed.
2. a kind of compound probiotic functional food for adjusting infantile enteritis immune response according to claim 1,
It is characterized in that：The mixing probiotics includes the composition of following mass fraction：
15-25 parts of bifidobacterium lactis, 5-10 parts of Lactobacillus rhamnosus, 15-25 parts of animal bifidobacteria, lactobacillus acidophilus 10-20
Part, 10-20 parts of lactobacillus reuteri, 15-25 parts of lactobacillus fermenti and 10-20 parts of bifidobacterium breve.
3. a kind of compound probiotic functional food for adjusting infantile enteritis immune response according to claim 1,
It is characterized in that：The mixing prebiotics include the composition of following mass fraction：
10-20 parts of 10-30 parts of oligofructose and oligoisomaltose.
4. the compound probiotic functionality food as claimed in any one of claims 1-3 for adjusting infantile enteritis immune response
The preparation method of product, it is characterised in that：Include the following steps：
(1) pretreatment of raw material：Each ingredient in mixing probiotics and mixing prebiotics is sized to 80 mesh hereinafter, then according to upper
Mass ratio is stated to be weighed, it is spare；
(2) raw material mixes：Load weighted each raw material is placed in dry-mixed machine and is uniformly mixed；
(3) press sheet formulation or directly pack：Raw material after mixing carries out press sheet formulation, or each raw material after mixing
Direct pack of weighing.
5. the preparation according to claim 4 for adjusting the compound probiotic functional food of infantile enteritis immune response
Method, it is characterised in that：When the step (2) carries out raw material mixing, dry-mixed machine rotating speed is set as 100-200rpm, mixes duration
It is set as 20-40 minutes.
6. the preparation according to claim 4 for adjusting the compound probiotic functional food of infantile enteritis immune response
Method, it is characterised in that：When the step (3) carries out press sheet formulation, pressure value is set as 4-5KN；Mix always filling out for raw material
Charge 5.0-6.0mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810991277.3A CN108741091A (en) | 2018-08-29 | 2018-08-29 | A kind of compound probiotic functional food for adjusting infantile enteritis immune response |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810991277.3A CN108741091A (en) | 2018-08-29 | 2018-08-29 | A kind of compound probiotic functional food for adjusting infantile enteritis immune response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108741091A true CN108741091A (en) | 2018-11-06 |
Family
ID=63966709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810991277.3A Pending CN108741091A (en) | 2018-08-29 | 2018-08-29 | A kind of compound probiotic functional food for adjusting infantile enteritis immune response |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108741091A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102511714A (en) * | 2011-12-21 | 2012-06-27 | 浙江康恩贝健康产品有限公司 | High-activity probiotic composition suitable for infants and preparation method thereof |
| CN104983746A (en) * | 2015-06-18 | 2015-10-21 | 合生元（广州）健康产品有限公司 | Complex probiotics and preparation method |
| CN107115364A (en) * | 2017-04-22 | 2017-09-01 | 北京市永康年健康科技有限责任公司 | A kind of compound probiotic and preparation method thereof |
| CN108295098A (en) * | 2018-02-02 | 2018-07-20 | 云南中京国建投资有限公司 | The symphysis unit composition and its preparation of a kind of auxiliary hyperglycemic and application |
| CN108741090A (en) * | 2018-08-28 | 2018-11-06 | 安徽谷益生物科技有限公司 | A kind of compound probiotic functional food inhibiting helicobacter pylori |
-
2018
- 2018-08-29 CN CN201810991277.3A patent/CN108741091A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102511714A (en) * | 2011-12-21 | 2012-06-27 | 浙江康恩贝健康产品有限公司 | High-activity probiotic composition suitable for infants and preparation method thereof |
| CN104983746A (en) * | 2015-06-18 | 2015-10-21 | 合生元（广州）健康产品有限公司 | Complex probiotics and preparation method |
| CN107115364A (en) * | 2017-04-22 | 2017-09-01 | 北京市永康年健康科技有限责任公司 | A kind of compound probiotic and preparation method thereof |
| CN108295098A (en) * | 2018-02-02 | 2018-07-20 | 云南中京国建投资有限公司 | The symphysis unit composition and its preparation of a kind of auxiliary hyperglycemic and application |
| CN108741090A (en) * | 2018-08-28 | 2018-11-06 | 安徽谷益生物科技有限公司 | A kind of compound probiotic functional food inhibiting helicobacter pylori |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107115364B (en) | A kind of compound probiotic and preparation method thereof | |
| CN107893044B (en) | One plant of bifidobacterium longum and its application | |
| Anukam et al. | African traditional fermented foods and probiotics | |
| CN102326678B (en) | Penta-composite probiotic powder preparation and preparation method thereof | |
| CN105454966A (en) | Probiotics solid beverage for improving gastrointestinal tract and immunity and preparation method thereof | |
| CN109329419A (en) | A kind of functional probiotics solid beverage and preparation method thereof for being able to maintain that intestinal health and improving immunity | |
| CN101496822A (en) | Composite probiotics micro-ecological formulation and preparation method | |
| CN108991327A (en) | A kind of probiotics solid beverage and preparation method thereof | |
| CN109123295A (en) | A kind of probiotics solid beverage and preparation method thereof | |
| CN109771470A (en) | A kind of composition and preparation method thereof containing probiotics | |
| CN104510779B (en) | A kind of Chinese medicine microecological preparation for treating cow subclinical mastitis | |
| CN108743851A (en) | A kind of preparation method and compound probiotic powder of compound probiotic powder | |
| CN108541951A (en) | A kind of symphysis unit composition and its preparation for preventing senile dementia, enhancing memory | |
| CN109566935A (en) | The preparation method of the comprehensive compound powder solid beverage of probiotics | |
| CN107279649A (en) | A kind of probiotics solid beverage formula and its manufacture method | |
| CN109288063A (en) | A kind of multi-joint Cernevit-12 and preparation method thereof being proliferated beneficial bacteria of intestinal tract | |
| CN110477105A (en) | A kind of probiotics solid beverage | |
| CN106721461A (en) | A kind of broiler fodder of enhance immunity and preparation method thereof | |
| CN112438402A (en) | Composite probiotics and preparation method thereof | |
| CN108641991A (en) | A kind of composite viable bacteria preparation and preparation method and its application | |
| CN108514121A (en) | A kind of defaecation, the symphysis unit composition of toxin expelling and its preparation and application | |
| CN107889997A (en) | A kind of Freeze-dry Powder of Probioctics solid beverage | |
| CN107865179A (en) | A kind of lactic acid bacteria milk calcium pressed candy and preparation method thereof | |
| CN108741091A (en) | A kind of compound probiotic functional food for adjusting infantile enteritis immune response | |
| CN107260785A (en) | Traditional Chinese medicine probiotic powder, preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181106 |
|
| WD01 | Invention patent application deemed withdrawn after publication |