CN108704678A - 摩斯码生成的t型微流控芯片装置 - Google Patents
摩斯码生成的t型微流控芯片装置 Download PDFInfo
- Publication number
- CN108704678A CN108704678A CN201810420350.1A CN201810420350A CN108704678A CN 108704678 A CN108704678 A CN 108704678A CN 201810420350 A CN201810420350 A CN 201810420350A CN 108704678 A CN108704678 A CN 108704678A
- Authority
- CN
- China
- Prior art keywords
- laser
- main channel
- morse code
- phase fluid
- type micro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 claims abstract description 27
- 239000007788 liquid Substances 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 7
- 239000007924 injection Substances 0.000 claims description 7
- 230000008033 biological extinction Effects 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 3
- 230000003313 weakening effect Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000010365 information processing Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- 230000005514 two-phase flow Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1023—Microstructural devices for non-optical measurement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/103—Particle shape
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Micromachines (AREA)
Abstract
本发明涉及一种摩斯码生成的T型微流控芯片装置,T型微流控芯片的微通道主通道前部设有连续相流体通道入口,尾部设有微通道出口,T型微流控芯片的微通道次通道设有分散相流体的通道入口,主通道尾部处设有激光发射器和激光接收器,通过控制从分散相流体的通道入口注入的分散相流体的流量来生成长液滴和短液滴,并在微通道主通道内显示出摩斯码的形式;激光发射器射出激光射线穿过主通道,使长度不一的长短液滴通过主通道时,输出激光强度的脉冲信号由激光接收器接收,以此来传递其所代表的摩斯码信号。本发明能借助微液滴产生明确的摩斯码信号,使新得到的摩斯码的传递可视化,更易于实现信息的准确传输与控制。
Description
技术领域
本发明涉及一种微流控芯片装置,尤其是一种通过控制主通道内不同长度的液滴间距组合出摩斯码来实现信息传递的装置。
背景技术
微流控技术及微流控芯片是近年来迅速发展的一个多学科交叉领域,在生物、化学分析、信息处理等方面有广泛应用。目前制备微型液滴的方法主要有使用喷嘴装置和使用微流控设备两种,微流控芯片设备制备原理如下:
两种互不相溶的液体(如水和油)相接触时由于表面张力的作用会形成相界面。将分别在不同通道中流动的互不相溶的连续相和分散相由压力或体积驱动,使两种流体在通道的交汇处接触,由于连续相对分散相的剪切或挤压作用,使得表面张力不足以维持界面稳定而发生断裂,进而生成分散相液滴。
相比于喷嘴等借助外部动力生成液滴的装置,微流控芯片装置只需要控制两相流体的流量比,黏性等物性因素来控制生成液滴的长度与生成频率,可实现对液滴尺寸的精准控制。
摩斯码在无线电信号传输,电子信息传递等领域有着广泛应用。通过点、横之间的组合来达到信息传递的目的。本发明中通过控制两相流体的入口流量来控制生成液滴的尺寸,从而在微流通道内形成类似于“点”与“横”的液滴,组成不同的摩斯码来达到信息传递的目的。
发明内容
本发明是要提供一种摩斯码生成的T型微流控芯片装置,控制T型微流控芯片产生长短不同的液滴来类比与摩斯码中的“点”与“横”,通过微通道中“点”液滴与“横”液滴的变换组合,产生不同的摩斯码,并通过通道尾部的激光传感器来转换成相应的脉通信号,来达到信号传递的目的.
为实现上述目的,本发明的技术方案是:一种摩斯码生成的T型微流控芯片装置,包括T型微流控芯片、激光发射器、激光接收器,所述T型微流控芯片的微通道主通道前部设有连续相流体通道入口,尾部设有微通道出口,T型微流控芯片的微通道次通道设有分散相流体的通道入口,主通道尾部处设有激光发射器和激光接收器,通过控制从分散相流体的通道入口注入的分散相流体的流量来生成长液滴和短液滴,并在微通道主通道内显示出摩斯码的形式;所述激光发射器射出激光射线穿过主通道,使长度不一的长短液滴通过主通道时,输出激光强度的脉冲信号由激光接收器接收,以此来传递其所代表的摩斯码信号。
所述T型微流控芯片的主通道注入的连续相流体中混入吸光物质,使混合后的连续相液体对摄入激光射线的强度显著削弱,而次通道注入的分散相流体为单组份液体,不影响激光射线的穿透性。
本发明的有益效果是:控制T型微流控芯片产生长短不同的液滴来类比与摩斯码中的“点”与“横”,通过微通道中“点”液滴与“横”液滴的变换组合,产生不同的摩斯码,并通过通道尾部的激光传感器来转换成相应的脉通信号,来达到信号传递的目的。相比于前者,该装置能借助微液滴产生明确的摩斯码信号,使新得到的摩斯码的传递可视化,更易于实现信息的准确传输与控制。
附图说明
图1为摩斯码生成的T型微流控芯片装置示意图;
图2 为摩斯码脉冲图像。
具体实施方式
下面结合附图与实施例对本发明作进一步说明。
如图1所示,本发明的摩斯码生成的T型微流控芯片装置,包括T型微流控芯片、激光发射器5、激光接收器6。T型微流控芯片的微通道主通道前部设有连续相流体通道入口1,尾部设有微通道出口7,T型微流控芯片的微通道次通道设有分散相流体的通道入口2,主通道尾部处设有激光发射器5和激光接收器6,通过控制从分散相流体的通道入口2注入的分散相流体的流量来生成长液滴和短液滴,并在微通道主通道内显示出摩斯码的形式;激光发射器5射出激光射线穿过主通道,使长度不一的长短液滴通过主通道时,输出激光强度的脉冲信号由激光接收器6接收,以此来传递其所代表的摩斯码信号。其中,生成的长液滴3用来代表摩斯码中的“—”,生成的短液滴4用来表示摩斯码中的“·”。
T型微流控芯片的主通道注入的连续相流体2中混入吸光物质,使混合后的连续相液体对摄入激光射线的强度显著削弱,而次通道注入的分散相流体为单组份液体,不影响激光射线的穿透性。
现对该设备摩斯码传递过程进行说明:在连续相液体中混入吸光物质,使混合后的连续相液体对摄入激光射线的强度有显著的削弱,分散相为单组份液体,不影响激光射线的穿透性。将连续相液体自连续相流体通道入口1处注入,分散相液体自分散相流体的通道入口2处注入,调节连续相的流量可以生成如长液滴3和短液滴4所示的长短液滴,由于连续相液体对激光射线强度的削弱性,当尺寸不一的液滴穿够激光发射器5发射的激光射线时,在激光接收器6中会接收到持续时间不一且不同强度的激光,经过处理后的激光强度信号会显示出如图2所示的摩斯码脉冲图像,以此达到传递信息的目的。例如图2中显示的脉冲图像表示的摩斯码为“— · · —”,其表示的意思为英文字母“X”。
Claims (2)
1.一种摩斯码生成的T型微流控芯片装置,包括T型微流控芯片、激光发射器、激光接收器,所述T型微流控芯片的微通道主通道前部设有连续相流体通道入口,尾部设有微通道出口,T型微流控芯片的微通道次通道设有分散相流体的通道入口,主通道尾部处设有激光发射器和激光接收器,通过控制从分散相流体的通道入口注入的分散相流体的流量来生成长液滴和短液滴,并在微通道主通道内显示出摩斯码的形式;所述激光发射器射出激光射线穿过主通道,使长度不一的长短液滴通过主通道时,输出激光强度的脉冲信号由激光接收器接收,以此来传递其所代表的摩斯码信号。
2.根据权利要求1所述的摩斯码生成的T型微流控芯片装置,其特征在于:所述T型微流控芯片的主通道注入的连续相流体中混入吸光物质,使混合后的连续相液体对摄入激光射线的强度显著削弱,而次通道注入的分散相流体为单组份液体,不影响激光射线的穿透性。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810420350.1A CN108704678A (zh) | 2018-05-04 | 2018-05-04 | 摩斯码生成的t型微流控芯片装置 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810420350.1A CN108704678A (zh) | 2018-05-04 | 2018-05-04 | 摩斯码生成的t型微流控芯片装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108704678A true CN108704678A (zh) | 2018-10-26 |
Family
ID=63867789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810420350.1A Pending CN108704678A (zh) | 2018-05-04 | 2018-05-04 | 摩斯码生成的t型微流控芯片装置 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108704678A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115193498A (zh) * | 2022-07-26 | 2022-10-18 | 之江实验室 | 一种陶瓷微流控芯片及其制备方法、应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101842159A (zh) * | 2007-08-09 | 2010-09-22 | 赛路拉公司 | 关联的多参数单细胞测定及残余生物材料回收的方法和装置 |
US20100297448A1 (en) * | 2005-09-13 | 2010-11-25 | True Randall J | Miniaturized microparticles |
CN106589412A (zh) * | 2016-11-28 | 2017-04-26 | 华南理工大学 | 一种基于微流控技术的聚合物微凝胶的制备方法 |
CN106807463A (zh) * | 2017-01-22 | 2017-06-09 | 北京大学 | 微流控芯片及应用其的微液滴产生装置 |
-
2018
- 2018-05-04 CN CN201810420350.1A patent/CN108704678A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100297448A1 (en) * | 2005-09-13 | 2010-11-25 | True Randall J | Miniaturized microparticles |
CN101842159A (zh) * | 2007-08-09 | 2010-09-22 | 赛路拉公司 | 关联的多参数单细胞测定及残余生物材料回收的方法和装置 |
CN106589412A (zh) * | 2016-11-28 | 2017-04-26 | 华南理工大学 | 一种基于微流控技术的聚合物微凝胶的制备方法 |
CN106807463A (zh) * | 2017-01-22 | 2017-06-09 | 北京大学 | 微流控芯片及应用其的微液滴产生装置 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115193498A (zh) * | 2022-07-26 | 2022-10-18 | 之江实验室 | 一种陶瓷微流控芯片及其制备方法、应用 |
CN115193498B (zh) * | 2022-07-26 | 2024-04-16 | 之江实验室 | 一种陶瓷微流控芯片及其制备方法、应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2411133B1 (en) | Droplet generator | |
US3228410A (en) | Fluid pulse width modulation | |
CN101376093B (zh) | 一种共轴微通道反应器的制备方法 | |
CN105925479B (zh) | 一种梯度3d打印喷头及3d打印机 | |
CN111701627B (zh) | 一种基于声表面波微流控的核壳液滴快速生成装置及方法 | |
CN108704678A (zh) | 摩斯码生成的t型微流控芯片装置 | |
CN105148760B (zh) | 一种制备微米级气泡分散体系的孔板喷射方法及装置 | |
CN114160218B (zh) | 一种制备单分散非牛顿微液滴的微流控装置及方法 | |
CN107120103B (zh) | 一种压裂酸化用助排剂 | |
CN103386336A (zh) | 一种用于生产浓度梯度微液滴的微流控芯片 | |
CN109927282A (zh) | 一种3d打印***及纤维的打印方法 | |
CN104405613A (zh) | 激光诱导微泵 | |
CN110624427A (zh) | 一种基于表面声波微流控的气泡生成装置及方法 | |
CN108499500A (zh) | 一种振动管路控制流动聚焦型微流控芯片生成微液滴的方法 | |
CN108579830A (zh) | 摩斯码生成的十字交叉型微流控芯片装置 | |
US6843262B2 (en) | Fluidic switches and methods for controlling flow in fluidic systems | |
CN106362811B (zh) | 一种测量壁面可变形通道中压力变化的微流控芯片 | |
CN108837719B (zh) | 一种液态金属液滴形成装置 | |
CN105214546B (zh) | 一种基于脉动流的震荡射流式微混合器 | |
CN110898699B (zh) | 一种基于气泡融合的微气泡发生装置 | |
CN108607376A (zh) | 一种基于振荡流的液滴融合方法及器件 | |
CN110449195A (zh) | 一种提高液滴在不对称通道***均匀度的装置 | |
CN111804353B (zh) | 一种实现微液滴被动融合的装置及其方法 | |
CN108654706B (zh) | 一种基于振荡流主动控制的液滴制备方法及器件 | |
CN202129066U (zh) | 一种微流控微球制备装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181026 |