CN108658923A - A method of extracting purple sweet potato cyanidin with acidic oxidized electric potential water - Google Patents
A method of extracting purple sweet potato cyanidin with acidic oxidized electric potential water Download PDFInfo
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- CN108658923A CN108658923A CN201810424361.7A CN201810424361A CN108658923A CN 108658923 A CN108658923 A CN 108658923A CN 201810424361 A CN201810424361 A CN 201810424361A CN 108658923 A CN108658923 A CN 108658923A
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
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Abstract
The invention belongs to nature strength technical fields, the problem of anthocyanidin technology being extracted for existing purple sweetpotato, anthocyanidin product is extracted using artificial acidic oxidized electric potential water economy, safe and effective method, and it extracts and obtains starch, protein and mucopolysaccharide product, the added value for improving purple sweetpotato provides a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water for the comprehensive utilization of characteristic purple sweetpotato.Purple sweetpotato cleans, and is impregnated with 2.0 4.5 artificial acidic oxidized electric potential water of pH value, broken and mashing, detaches potato slag, natural sedimentation, and upper layer anthocyanidin aqueous solution carries out filtering and membrane filtration twice, and filtrate is concentrated to give cream state anthocyanidin through absorption, elution；Cream state anthocyanidin drying and crushing obtains solid-state anthocyanidin product；The present invention reduces chemical reagent and water consumption, improves product yield, ensures that extraction anthocyanidin stable structure, purple sweetpotato are comprehensively utilized, improves added value, economic benefit, social benefit and environmental benefit are preferable.
Description
Technical field
The invention belongs to nature strength technical fields, and in particular to a kind of to extract purple sweetpotato with acidic oxidized electric potential water
The method of anthocyanidin.
Background technology
As people have deeper understanding, the raising of quality of life, back to nature to advocate day synthetic dyestuff harmfulness
Right pigment is gladly received by consumer, expensive although natural pigment is limited by processing conditions, because of its Nantural non-toxic,
It is worth with nutrition and health care, natural pigment promise well.
Purple sweetpotato（Ipomoes batatas), also known as purple sweet potato, purple sweet potato are morning glory.Purple sweetpotato root tuber
In contain Ipomoea batatas(L.)Lam, starch, protein, much more viscous viscous and metallic elements etc..Ipomoea batatas(L.)Lam（Ipomoea batatas
(L.) Lam), also known as anthocyanidin（Anthocyanins), anthocyanidin is one of the primary pigments for constituting petal and fruit color.
Ipomoea batatas(L.)Lam category anthocyanidin, is primarily present in the vacuole of purple sweetpotato cell, and key component is cyanidin and Chinese herbaceous peony
Pigment is anthocyanidin, is a kind of water colo(u)r, and content is 2-3 times of anthocyanidin content in red cabbage and carrot,
Not only pure color, stability are better than the pigments such as careless battalion, grape, purple perilla, red cabbage, and have stronger heat resistance and fast light
Property.Ipomoea batatas(L.)Lam can change color with the soda acid of cell liquid.Cell liquid is then partially red in acidity, and cell liquid is then inclined in alkalinity
It is blue.Purple sweetpotato can plant in China majority area, be a natural food colour source that is important, deriving from a wealth of sources.Chemically
Said in structure, such pigment has for example anti-oxidant important physiological active functions, anti-mutation, active anticancer, have protection liver,
Improve liver function, reduce gene mutation, inhibit the generation of carcinogen, improve eyesight, prevention of cardiovascular disease and other effects is
The functional food additive and Material for Health Food of a kind of great future.The basic structural unit of anthocyanidin is 2-phenyl benzene
And pyranoid form cation, i.e. pattern primitive.Existing known cyanine is known as more than 20 kinds, is primarily present in plant.The base of anthocyanidin
This structural unit is 2-phenyl benzopyrane type cations, i.e. pattern primitive.Chemical structural formula is：
。
The stability of purple sweet potato cyanidin in the beverage be more than commercially available food coloring, anthocyanidin by most countries such as
China, Japan, the U.S. and EU member country etc. all allow it to be used for food color.Be widely used in beverage, candy, jelly and
In jam.
Sweet potato contains a large amount of mucus, is the mixture of mucopolysaccharide and collagen, and Japanese medical university river original professor group points out：It is viscous
Liquid polysaccharide can improve the immune function of human body, enhance disease resistance, and keep arterial vascular elasticity, prevent liver, kidney knot
Telatrophy is formed, the generation of the collagen diseases such as heart disease, kidney trouble, hypertension, neuropathy, rheumatism and arthritis is prevented.Human body
Sperm and the genic nucleic acid such as ovum be exactly mucous substance, it is seen that the substances such as mucopolysaccharide and collagen of sweet potato are exactly life
Base substance.Digestive system of the human body from oral cavity to stomach and intestine, and from nasal cavity to tracheae, the respiratory system and uropoiesis of the lobe of the lung
Reproductive system, surface are all covered by the mucous membrane full of mucus, once mucus is reduced, be easy for causing each organ inflammation and
Canceration.The glue polysaccharide substance that such important function is played for life, which is rice, face, chicken, duck, fish, meat, to be supplied, and
Sweet potato but very abundant.
Sweet potato matter content is 6%, contains 8 kinds of essential amino acid ratios relatively international food and agricultural organization（FAO egg)
White standard, therefore the protein utilization rate of sweet potato is up to 72%, and soybean protein utilization rate is 57%, fine flour protein utilization rate is 52%.
U.S.'s crin this it is demonstrated experimentally that sweet potato root tuber albumen be better than casein, illustrate that the quality of sweet potato is relatively high.Wherein viscous egg
In vain, glycoprotein has healthcare function.
Currently, the production method of purple sweet potato cyanidin mainly has：Acidified with citric acid aqueous extraction method, acidic ethanol extraction,
Enzyme process, ultrasonic wave and impulse electric field.Above-mentioned first two extract by solvents is simple for process, but pigment recovery rate is low, need extracted many times,
Finished product purity is low, and color value is low；Foreign countries mostly use acidified methanol, sulfuric acid, acetic acid or aqueous hydrochloric acid solution extraction；It is domestic then use lemon
Lemon acid, aqueous hydrochloric acid solution and acidic ethanol are as extracting solution.Ultrasonic wave and impulse electric field method can effectively destroy cell wall and thin
After birth improves histiocytic permeability, shortens extraction time, improves anthocyanidin yield, improves the quality of product.However,
A large amount of losses of natural anthocyanidin often occur in the process such as extraction and purifying, equipment investment is big.Enzyme process is then production
Period is long, and occupied ground is more.Currently, there are one problems for the production of purple sweet potato cyanidin, it is that high-quality starch becomes production wine
The raw material of essence, polysaccharide and protein can not be utilized.
Invention content
It is an object of the invention to be directed to the problem of existing purple sweetpotato extracts anthocyanidin technology, using artificial acidity
Electrolyzed oxidizing water economy, safe and effective method extract anthocyanidin product, and extract and obtain starch, protein and mucopolysaccharide production
Product improve the added value of purple sweetpotato, for characteristic purple sweetpotato comprehensive utilization provide it is a kind of purple sweet with acidic oxidized electric potential water extraction
The method of potato anthocyanidin.
The present invention adopts the following technical scheme that realization：A kind of side extracting purple sweet potato cyanidin with acidic oxidized electric potential water
Method, including clean, be crushed, being beaten, filtering, adsorbing, eluting and enrichment process, the specific steps are：
（1）Cleaning, broken, mashing：Purple sweetpotato is cleaned with the acidic oxidized electric potential water that pH value is 2. 0-6. 0, then uses pH value
It is impregnated at normal temperatures for the acidic oxidized electric potential water of 2.0-3.0, the ratio for controlling acidic oxidized electric potential water and purple sweetpotato is 10 public
It rises：0.5-10 kilograms；Control 3. 0-4. 5 of soaking solution pH value；It is beaten, controls after being crushed to 100-500 mesh or 15-100 microns
System mashing solution ph 4.0-4.5, natural sediment, separation potato slag obtain slurries；Upper layer aqueous solution is used for detaching anthocyanidin；Under
Layer colloidal sol is spare；
（2）Filtering, absorb-elute：Slurries are once filtered, and detach purple sweetpotato Crude starch, it is further that filtrate carries out secondary filter
Purple sweetpotato Crude starch is detached, the filtrate filtered twice ultrafiltration membrane membrane filtration recycles thick protein and mucopolysaccharide, and then filtrate uses
Macroporous resin adsorption, flow velocity 1250-1300L/h use pH value for the acidic oxidized electric potential water speed 2000L/h of 3. 0-6.0
Elution, to efflux clarify until, then again use organic solvent ethyl alcohol, methanol, n-butanol or acetone in any one with
PH value is that the acidic oxidized electric potential water mixed solution of 4.0-7.0 is eluted, a concentration of 20- of organic solvent in mixed solution
60%, the pH value of mixed solution is 5.5-6.5；
（3）Concentration：Eluent is through conventional reduced pressure, and controlled at 60-65 DEG C, concentrate is controlled in 15-16 Baume degrees, is obtained
Cream state anthocyanidin.
The cleaning is once cleaned using squirrel-cage cleaning machine, is then further cleaned in rinse bath.Using spiral shell
Bar crusher in crushing to 15-100 microns, filtered with bent net extruder filtering, secondary filter using centrifuge by primary filtering；Ultrafiltration
Within the scope of 50~500nm, operating pressure is 0.11~0.6Mpa in hymeniderm layer aperture, when temperature is less than 60 DEG C, the film of ultrafiltration membrane
Flux is with 1~500L/m2h.
Prepared cream state anthocyanidin air drying, crushes to obtain solid-state anthocyanidin.
The acidic oxidized electric potential water that recycle-water is added in the Crude starch, pH value is 2.0-3.0, control solution ph are 4.0-
5.2 are washed, and dehydration recycling mother liquor is spare, and precipitation is dry, crushing obtains purple sweet potato starch product.Lower layer after the mashing
The reduced pressure of 60-65 DEG C of colloidal sol, concentrate control are dry, pulverize and sieve to obtain protein and mucopolysaccharide in 15-16 Baume degrees.
Isolated in all process steps water or mother liquor or organic solvent recycling use, waste residue prepare according to a conventional method feed and
Fertilizer.
When conventional method extracts anthocyanidin, in the slurry process before being extremely concentrated under reduced pressure after cleaning due to purple sweetpotato, to purple sweet
The fine locellus of potato cell is broken, and anthocyanidin is directly exposed in the enzyme in air and cell juice, easily leads to oxygenolysis,
Therefore, some anthocyanidin can be destroyed.The present invention in the process to before being concentrated under reduced pressure, is all made of weakly acidic acid oxygen after cleaning
Change electric potential water to impregnate, rinse；Anthocyanidin is protected, to improve the quality and yield that purple sweetpotato extracts anthocyanidin.
At present in the production of purple sweet potato cyanidin, it is beaten using curing or fermentation, good purple sweet potato starch becomes
The raw material of alcohol is produced, good mucopolysaccharide and albumen are also not fully utilized.The present invention is after cleaning to before being concentrated under reduced pressure
Process in, be all made of acidic oxidized electric potential water extraction, normal-temperature operation, effective protection ative starch, and control the pH value of protein
Protein and mucopolysaccharide product are effectively recycled with using Ultra filtration membrane technology, to improve the synthesis that purple sweetpotato extracts anthocyanidin
Utility value.
Currently, the production method of purple sweet potato cyanidin mainly has：Acidified with citric acid aqueous extraction method or acidic ethanol extraction,
Acidified with citric acid aqueous extraction method, using citric acid, aqueous hydrochloric acid solution and acidic ethanol as extracting solution, but pigment recovery rate it is low,
Need extracted many times, finished product purity low, color value is low, impurity height and of high cost.The present invention is after cleaning to the process before reduced pressure
In, it is all made of the extraction of no pollution acidic oxidized electric potential water, at low cost, the advantages that color value is high, no pollution and friendly process.
The advantages and positive effects of the present invention：
1, in the process before technical solution of the present invention is extremely concentrated under reduced pressure after cleaning, it is all made of faintly acid acidic oxidized electric potential water guarantor
Anthocyanidin is protected, to improve the quality and yield that purple sweetpotato extracts anthocyanidin.It overcomes since purple sweetpotato is after cleaning to decompression
In process before concentration, the fine locellus of purple sweetpotato cell is broken, anthocyanidin is directly exposed in air and cell juice
Enzyme in, easily lead to oxygenolysis, destroy the chemical constitution problem of some anthocyanidin.
2, in the process before technical solution of the present invention is extremely concentrated under reduced pressure after cleaning, normal-temperature operation, effective protection are all made of
Ative starch, and albumen and mucopolysaccharide product are effectively recycled, to improve the comprehensive utilization that purple sweetpotato extracts anthocyanidin.Overcome mesh
Preceding to be beaten or fermented using curing in the production of purple sweet potato cyanidin, good purple sweet potato starch becomes production alcohol
Raw material, good mucopolysaccharide and albumen are also not fully utilized.
3, technical solution of the present invention controls the pH value of protein and uses Ultra filtration membrane technology, carries out recycling thick protein
And mucopolysaccharide, product yield is high, good product quality.
4, anthocyanidin is extracted from purple sweetpotato using acidic oxidized electric potential water, anthocyanidin can be effectively protected, reduction was extracted
Loss in journey, overcomes that existing extract by solvents is simple for process, and pigment recovery rate is low, finished product purity is low, the low technology of color value
Quality problems, while albumen and mucopolysaccharide product are produced, water or mother liquor or the organic solvent recycling that each process is isolated just are used, and are subtracted
Few chemical reagent and water consumption, improve product yield, and waste residue is used as feed and fertilizer, is comprehensively utilized, improves purple sweetpotato
Added value, economic benefit, social benefit and environmental benefit are preferable.
The acidic oxidized electric potential water extraction of the present invention is that no pollution plant extract technology its technique is not only simple, but also operates
Cost is relatively low, is suitble to the large-scale production of extraction anthocyanidin.Efficiently, pollution-free, technique realize during do not introduce new impurity,
New pollution sources are not will produce, realization recycles Extraction solvent, greatly reduces the waste of energy consumption and resource.Phase
For conventional extraction method in order to achieve the purpose that recovery rate is high, a certain amount of additive is often added（Such as lemon
Acid）, not only result in product and remain, extracting solution can not be reused.Acidic oxidized electric potential water plant extract technology is to purple sweet
Potato extraction anthocyanidin extraction, which then successfully overcomes in extraction process nuisance residual, solvent can not recycle, recovery rate is low etc. asks
Topic is removed the obstacles for scale, green, efficient production.No pollution acidic oxidized electric potential water plant extract technology is very suitable for
Another be particularly advantageous in that of the large-scale production of functional component in purple sweet potato cyanidin, the technology can be according to extraction rank
Section, the different of purpose carry out selective adjustment to technological parameter, are the height of functional component to adapt to the needs of optimum production process
Efficiency extraction creates inherent advantage.
Specific implementation mode
Embodiment 1：A method of purple sweet potato cyanidin being extracted with acidic oxidized electric potential water, including cleans, be crushed, beat
Slurry, filtering, absorption, elution and enrichment process extract purple sweet potato cyanidin, purple sweet potato starch, protein and mucopolysaccharide production respectively
Product, the specific steps are：
One, the preparation of purple sweet potato cyanidin product
Using acidic oxidized electric potential water（PH value is 2. 0-6. 0）By purple sweetpotato input squirrel-cage cleaning machine cleaning, then clear
Washing trough is further cleaned.Soak at room temperature in purple sweetpotato input soaking compartment, is added acidic oxidized electric potential water, control is impregnated after cleaning
3. 0-4. 5 of solution pH value.It will impregnate in purple sweetpotato input screw rod crusher, while recycling mother liquor be added or water room temperature is broken,
It is beaten through beater room temperature, 4. 0-4. 5 of control mashing solution pH value, separation potato slag is spare, by slurries natural sedimentation.It takes
Layer anthocyanidin aqueous solution is added bent net extruder and carries out first time filtering, and separation purple sweetpotato Crude starch is spare.Filtered fluid is used again
Centrifuge filtering carries out second and filters, and separation purple sweetpotato Crude starch is spare.Filtered fluid through filtering twice is carried out with ultrafiltration membrane
Membrane filtration, recycles thick protein and mucopolysaccharide is spare, then uses macroporous resin adsorption, coutroi velocity 1250L/h again.Filtering is adsorbed
After liquid, the acidic oxidized electric potential water washing desorption of speed 2000L/h is first used, until being washed till efflux clarification, is then used dense
Degree is the solvent ethanol water of 20-60 %, and the pH value of acidic oxidized electric potential water control solvent is added（6. 0 or so）It carries out
Elution, eluent obtain cream state anthocyanidin product in 60-65 DEG C of reduced pressure of temperature, concentrate control in 15-16 Baume degrees.
Cream state anthocyanidin does behaviour according to a conventional method, crushes and sieving obtains the wide product of solid-state anthocyanidin.
Two, the preparation of purple sweet potato starch product
Recycle-water is added in precipitation and the Crude starch of filtering, the acidic oxidized electric potential water that pH value is 2. 0-3. 0 is added, controls water
Solution ph 4. 0-4. 2 washings, dehydration recycling mother liquor is spare, does behaviour according to a conventional method, crushes and sieving obtains purple sweetpotato shallow lake
Powder product；
Three, the preparation of purple sweetpotato protein and mucopolysaccharide product
Lower layer's colloidal sol is controlled in 60-65 DEG C of reduced pressure of temperature, concentrate in 15-16 Baume degrees, then does behaviour according to a conventional method,
It crushes and sieving obtains albumen and mucopolysaccharide product.
The recycling of water or mother liquor or organic solvent that the above each process is isolated uses, waste residue prepare according to a conventional method feed and
Fertilizer.
Embodiment 2：A method of purple sweet potato cyanidin being extracted with acidic oxidized electric potential water, including cleans, be crushed, beat
Slurry, filtering, absorption, elution and enrichment process extract purple sweet potato cyanidin, purple sweet potato starch, protein and mucopolysaccharide production respectively
Product, the specific steps are：For the weak acid used for acidic oxidized electric potential water, organic solvent is acetone, macroporous resin adsorption flow velocity
1300L/h, acidic oxidized electric potential water wash desorption rate 2500L/h, other techniques are the same as example 1.
Embodiment 3：A method of purple sweet potato cyanidin being extracted with acidic oxidized electric potential water, including cleans, be crushed, beat
Slurry, filtering, absorption, elution and enrichment process extract purple sweet potato cyanidin, purple sweet potato starch, protein and mucopolysaccharide production respectively
Product, specific absorption, elution step are：It is first eluted using acidic oxidized electric potential water, is then eluted with organic solvent,
It is 10%-80% that middle organic solvent, which is acidic oxidized electric potential water with n-butanol or acetone according to volume ratio,：90%-20%, macroreticular resin
Adsorption flow rate 1280L/h, acidic oxidized electric potential water wash desorption rate 2300L/h, other techniques are the same as example 1.Macroporous resin purification
When use acidic oxidized electric potential water and ethyl alcohol etc. as eluant, eluent, ethyl alcohol is isolated using nanofiltration, ethyl alcohol can be recycled.It is whole
A technique uses physical method, does not use any poisonous and harmful solvent, and the energy is relatively low, is effectively protected environment；
Embodiment 4：A method of purple sweet potato cyanidin being extracted with acidic oxidized electric potential water, including cleans, be crushed, being beaten, mistake
Filter, absorption, elution and enrichment process extract purple sweet potato cyanidin, purple sweet potato starch, protein and mucopolysaccharide product, tool respectively
Body absorption, elution step are：It is first eluted using acidic oxidized electric potential water, is then eluted with organic solvent, wherein having
Solvent is ethyl alcohol, macroporous resin adsorption flow velocity 1300L/h, acidic oxidized electric potential water washing desorption rate 2300L/h, other works
Skill is the same as example 1.It uses acidic oxidized electric potential water and ethyl alcohol etc. as eluant, eluent when macroporous resin purification, second is isolated using nanofiltration
Alcohol, ethyl alcohol can be recycled.Entire technique uses physical method, does not use any poisonous and harmful solvent, and the energy is relatively low, has
Effect ground environmental protection.Anthocyanidin is preferably protected not to be destroyed using acidic oxidized electric potential water extraction and purification process：We are real
It verifies bright：Containing weakly acidic acidic oxidized electric potential water（PH value 4.5 to 6.5）Anthocyanidin structure is protected not to be destroyed for eluant, eluent.
Farthest retain anthocyanidin not to be destroyed.
The raw material of the present invention is plant, great revolution and the significant innovation of biology and traditional Chinese medicine extraction purification technique and industry.
It redefines and changes conventional solution extraction method comprehensively.Acidic oxidized electric potential water and acid-base property of the present invention
Reduction potential water extracting method can be adapted for current vast numerous active components of plants extraction or bioprotein extraction with
And the extraction of any one of Chinese medicine Chinese medicine active constituent.Such as include but not limited to that can be used for extracting kuh-seng in kuh-seng
Alkali；Extract the Method of Polysaccharide in Radix Pinellia in the tuber of pinellia；Extract the anthocyanidin in the wild cherry certain kind of berries；Extract polyphenol and polypeptide active ingredient in walnut；It carries
Take polysaccharide and saponin(e in Radix Astragali；Extract the Method of Polysaccharide in Radix Pinellia of the tuber of pinellia；Extract the carthamin yellow in safflower；It extracts different sweet in Radix Glycyrrhizae
Careless element；Extract the betel nut biotin in betel nut；Extract active ingredient cumarin, flavones and the Codonopsis pilosula polysaccharide in Radix Codonopsis；Extract soft-shelled turtle
Chitin in first；Extract the saikosaponin a in radix bupleuri；Extract the collagen in Animal Skin；Extract the polysaccharide in seaweed；It carries
Take the polysaccharide in jujube；Extract the peppermint oil in peppermint；Extract the epigoitrin in Radix Isatidis；Extract the Paeoniflorin in Radix Paeoniae Alba；
Extract the ginsenoside in ginseng；Extract the Puerarin in pueraria lobata；Extract the general flavone etc. in Sculellaria barbata.
The extracting method that specifically present invention is established can be adapted for any one of current Chinese medicine Chinese medicine.Example
It such as can be used for asafoetide, folium artemisiae argyi, styrax, the seed of Oriental arborvitae, turtle shell, betel nut, peppermint, castor bean, pivots storage, psoralea corylifolia, Radix Isatidis, Bi
It is the roots of grass, crotons, Morinda officinalis, rhizoma menispermi, Radix Glehniae, bletilla, the Chinese bulbul, Radix Paeoniae Alba, the root of Dahurain angelica, rhizoma typhonii, rhizoma imperatae, gingko, Cynanchum glaucescens, white
Hyacinth bean, radix ampelopsis, the root bark of shaggy-fruited dittany, radix cynanchi atrati, Chinese lobelia, Sculellaria barbata, the tuber of pinellia, lily, borneol, cicada slough, Paper mulberry Fruit, Changshan, bark of tree of heaven, Chuan Shan
First, Herba Andrographitis, rde bean, red halloysite, radix paeoniae rubra, rhizoma atractylodis, the achene of Siberian cocklebur, agalloch eaglewood, stringy stonecrop, cacumen biotae, radix aconiti agrestis, fohum aconiti kusnezoffii, careless beans
Cool, tsaoko, bulbus fritillariae cirrhosae, radix cyathulae, monkshood, Rhizoma Chuanxiong, Fructus meliae toosendan, plantain seed, Radix Salviae Miltiorrhizae, Fermented Soybean, Radix Codonopsis, lophatherum gracile, Cortex Eucommiae, solely
Work, arisaema cum bile, setose thistle, the shell of areca nut, moutan bark, calcined gypsum, waxgourd peel, cordyceps sinensis, earthworm, the fruit of summer cypress, the root bark of Chinese wolf-berry, radix rehmanniae preparata
Huang, Herba Euphorbiae Humifusae, garden burnet, Radix Angelicae Sinensis, rush, cloves, sword bean, folium isatidis, jujube, rheum officinale, Centipeda minima, curcuma zedoary, catechu, Chinese torreya
Son, duckweed, Bi solutions, raspberry, fingered citron, monkshood, Poria cocos, the root of fangji, windproof, folium sennae, honey, gekko, cassia twig, pueraria lobata, Jehol Ligusticum Rhizome,
Galangal, the rhizome of davallia, rice sprout, pipewort, rhizoma cibotii, the fruit of Chinese wolfberry, holly leaf, uncaria, rhizoma nardostachyos, Radix Glycyrrhizae, the root of gansui, Snakegourd Fruit, Chinese Drug Gualouzi,
PERICARPIUM TRICHOSANTHIS, caulis aristologhiae manshuriensis, rhizoma zingiberis, baked ginger, dried lacquer, Lappula echinata, Radix Astragali, sealwort, seaweed, sophora flower, caulis piperis futokadsurae, lotus leaf, radix scutellariae, the coptis,
It is Cortex Phellodendri, Chinese prickly ash, the fleece-flower root, giant knotweed, Radix picrorrhizae, Cortex Magnoliae Officinalis, Exocarpium Citri Grandis, fructus cannabis, cortex albiziae, Flos Albiziae, Knoxia valerianoide, safflower, black
Sesame, chrysanthemum, stiff silkworm, campanulaceae, tangerine seed, turmeric, Caulis Spatholobi, cockscomb, tinosporae, gold boiling grass, cymose buckwheat rhizome, desmodium, gold and silver
Flower, dalbergia wood, schizonepeta, semen allii tuberosi, cassia seed, tussilago, myrobalan, semen armeniacae amarae, kuh-seng, azedarach, radish seed, stone-like omphalia, Chinese trumpet creeper,
Pyrola, Radix Rhapontici seu Radix Echinopsis, Fructus Liquidambaris, lotus seeds, caulis trachelospermi, aloe, reed root, pointed at both ends, Radix zanthoxyli, Fructus Forsythiae, ganoderma lucidum, Folium Apocyni Veneti, sieve
Chinese fruit, semen litchi, rough gentian, arillus longan, geranium wilfordii, eclipta, Chinese ephedra, fructus viticis, Rhododendron dauricum, daurian rhododendron oil, butterflybush flower, plum
Flower, Chinese ephedra, Radix Ophiopogonis, malt, rose, Radix changii, Verbena officinalis, birthwort, vomiting nut, prepared nux vomica, Lasiosphaera fenzlii, purslane, wood
Melon, root of Aucklandia lappa Decne, scouring rush, adenophora tetraphylla, the fruit of glossy privet, great burdock achene, the root of bidentate achyranthes, rhizoma nelumbinis, dandelion, cattail pollen, loguat leaf, eupatorium, rhizoma curcumae longae concisa, Qu
Wheat, the bark of ash, adder-wort, Gorgon fruit, Rhizoma Et Radix Notopterygii, dutchmanspipe root, caulis sinomenii, green peel, the seed of feather cockscomb, sweet wormwood, indigo naturalis, madder, kaladana, the root of purple-flowered peucedanum,
Rhizoma homalonemae, moleplant seed, bark of ash, Hedge Prinsepia Nut, nutmeg, Herba Cistanches, Chinese cassia tree, ginseng, folium panacis japonici cum caule, grass-leaved sweetflag, cynomorium songaricum, mulberry leaf, Phytolacca acinosa,
Mulberry fruit, frutus cnidii, the root bark of white mulberry, ramulus mori, ramulus mori, Ramulus Taxilli, buckeye, spina date seed, blackberry lily, storax, semen astragali complanati, the fruit of Rangoon creeper,
The calyx and receptacle of a persimmon, fructus amomi, subprostrate sophora, Fructus Corni, Chinese yam, edible tulip, hawthorn, field thistle, cimicifugae foetidae, cornu bubali, PULVIS CORNUS BUBALI CONCEN TRATUS, pyrrosia lingua,
The shell of seaear, the stem of noble dendrobium, granatum, ginger, luffa, Radix Notoginseng, trigone, lepidium seed, Semen Cuscutae, peach kernel, the stem pith of the rice-paper plant, santal, root of Chinese trichosanthes,
Tabasheer, rhizoma arisaematis, Rhizoma Gastrodiae, radix semiaquilegiae, radix pseudostellariae, Golden Larch Bark, smilax, evodia rutaecarpa, the root of Chinese clematis, the seed of cowherb, cortex acanthopanacis,
Schisandra chinensis, Chinese gall, blood clam, the root of three-nerved spicebush, dark plum, decumbent corydalis tuber, teasel root, Inula britannica chinensis, Common St.Paulswort Herbs, Longstamen Onion Bulb, Prunella vulgaris, the flower bud of lily magnolia, perfume (or spice)
Add skin, rhizoma cyperi, citron, elscholtiza, fennel seeds, thizoma curculiginis, hairyvein agrimony, radix scrophulariae, the compound of glauber-salt and liquorice, American Ginseng, carbonized hair, dragon's blood, paniculate swallowwort,
Herba Epimedii, motherwort, ginkgo leaf, coix seed, radix stellariae dichotomae, Radix Polygalae, lilac daphne, brush-cherry seed, Radix Curcumae, cordate houttuynia, oriental wormwood, Java brucea,
China rose, radix polygonati officinalis, corydalis tuber, fritillaria thunbergii, fructus gleditsiae, perilla seed, aster, Chinese violet, Asian puccoon, umbellate pore furgus, spina gleditsiae, rhizoma anemarrhenae,
Herba Lycopi, rhizoma alismatis, mother-of-pearl, the dried immature fruit of citron orange, cape jasmine.
Any type in pharmacy can be made according to the plant or active ingredient of Chinese herbs of the extracted acquisition of the method for the present invention
Form, including injection and oral preparation.Wherein injection includes injection, drip solution, powder-injection；Oral preparation include granule,
Tablet, electuary, powder, oral solution, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule
Agent, mouth containing agent, granule, pill, paste, sublimed preparation, spray, pill, disintegrant, oral disintegrating tablet, pellet etc..
To those skilled in the art, according to technology contents disclosed in this invention, those skilled in the art will very
Understand that other embodiments of the present invention, the embodiment of the present invention are only used as example.In the feelings for not violating present subject matter and range
Under condition, various changes and improvement can be carried out to the present invention, for example, selected solution can be other lower alcohols either other
Organic solvent, but as long as using extracting method of the present invention, within the scope of the present invention.
Claims (7)
1. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water, including clean, be crushed, be beaten, filter, inhale
Attached, elution and enrichment process, it is characterised in that：The specific steps are：
（1）Cleaning, broken, mashing：Purple sweetpotato is cleaned with the acidic oxidized electric potential water that pH value is 2. 0-6. 0, then uses pH value
Acidic oxidized electric potential water for 2. 0-3. 0 impregnates at normal temperatures, and the ratio for controlling acidic oxidized electric potential water and purple sweetpotato is 10
Litre：0.5-10 kilograms；Control 3. 0-4. 5 of soaking solution pH value；It is beaten after being crushed to 100-500 mesh or 15-100 microns,
Control mashing 4. 0-4. 5 of solution ph, natural sediment, separation potato slag obtain slurries；Upper layer aqueous solution is used for detaching cyanine
Element；Lower layer's colloidal sol is spare；
（2）Filtering, absorb-elute：Slurries are once filtered, and detach purple sweetpotato Crude starch, it is further that filtrate carries out secondary filter
Purple sweetpotato Crude starch is detached, the filtrate filtered twice ultrafiltration membrane membrane filtration recycles thick protein and mucopolysaccharide, and then filtrate uses
Macroporous resin adsorption, flow velocity 1250-1300L/h use pH value for the acidic oxidized electric potential water speed 2000L/h of 3. 0-6.0
Elution, to efflux clarify until, then again use organic solvent ethyl alcohol, methanol, n-butanol or acetone in any one with
PH value is that the acidic oxidized electric potential water mixed solution of 4.0-7.0 is eluted, a concentration of 20- of organic solvent in mixed solution
60%, the pH value of mixed solution is 5.5-6.5；
（3）Concentration：Eluent is through conventional reduced pressure, and controlled at 60-65 DEG C, concentrate is controlled in 15-16 Baume degrees, is obtained
Cream state anthocyanidin.
2. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：The cleaning is once cleaned using squirrel-cage cleaning machine, is then further cleaned in rinse bath.
3. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：Using screw rod crusher in crushing to 15-100 microns.
4. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：Primary filtering is filtered with bent net extruder filtering, secondary filter using centrifuge；Ultrafiltration membrane cortex aperture is in 50~500nm
In range, operating pressure is 0.11~0.6Mpa, and when temperature is less than 60 DEG C, the membrane flux of ultrafiltration membrane is with 1~500L/m2h.
5. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：Prepared cream state anthocyanidin air drying, crushes to obtain solid-state anthocyanidin.
6. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：The acidic oxidized electric potential water that recycle-water is added in the Crude starch, pH value is 2.0-3.0, control solution ph be 4.0-5.2 into
Row is washed, and dehydration recycling mother liquor is spare, and precipitation is dry, crushing obtains purple sweet potato starch product.
7. a kind of method for extracting purple sweet potato cyanidin with acidic oxidized electric potential water according to claim 1, feature exist
In：60-65 DEG C of reduced pressure of lower layer's colloidal sol after the mashing, concentrate control pulverize and sieve in 15-16 Baume degrees, drying
Obtain protein and mucopolysaccharide.
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| CN111020598A (en) * | 2019-12-31 | 2020-04-17 | 扬州大学 | Preparation and antifouling evaluation method for traditional Chinese medicine extracted cyclic peptide modified metal surface |
| CN111040871A (en) * | 2019-12-11 | 2020-04-21 | 山西潞安石圪节智华生物科技有限公司 | Method for extracting peony seed oil |
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Application publication date: 20181016 |