CN108653476A - One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine - Google Patents
One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
- A23F3/30—Further treatment of dried tea extract; Preparations produced thereby, e.g. instant tea
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/7016—Disaccharides, e.g. lactose, lactulose
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/605—Morus (mulberry)
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- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
Reduce internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine the invention belongs to health industry technical field, especially one kind, is made of the raw material of following parts by weight：28 ~ 32 parts of Chinese olive, 6.4 ~ 7 parts of mountain chrysanthemum, 14 ~ 15 parts of dried orange peel, 17 ~ 19 parts of mulberry leaf, 14 ~ 15 parts of the sterculia seed, 15 ~ 17 parts of Siraitia grosvenorii, 6.5 ~ 7.3 parts of purple perilla, 14 ~ 15 parts of campanulaceae, 6 ~ 7 parts of green tea powder, 12 ~ 14 parts of rock sugar；So that drug effect is double, anti-inflammatory of effectively reducing internal heat, pharynx-clearing throat-benefiting, clearing heat and detoxicating, swelling and pain relieving so that breath freshening, it is relieving cough and reducing sputum, analgesia is eliminated, is whetted the appetite, resource utilization is improved, it is without any side effects, and can effectively promote the fragrant of Tea containing traditional Chinese medicine entirety, gastrointestinal health is effectively facilitated, warm stomach nourishing the stomach inhibits the growth of harmful intestinal tract bacteria, promote the proliferation of beneficial bacterium, enhance gastrointestinal tract ability, the generation of intestines problem, promotion is inhibited to assimilate conversion ratio to nutriment.
Description
Technical field
Reduce internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine the invention belongs to health industry technical field, especially one kind.
Background technology
Tea is Chinese tradition drink, and as people's demands for quality of life are getting higher and higher, various health protection teas answer
It transports and gives birth to, and since present life work pressure is bigger, it often stays up late, causes to get angry, there is inflammation, especially some life stress
Greatly, the crowd of 20 ~ 40 years old fast age bracket of work rhythm, body often in sub-health state, since these situations are from table
See that these problems of body are often ignored when more there is no having what too big influence to life on face；If be directed to
The above problem takes drug therapy, many people can be because body does not have special sense of discomfort or symptom unobvious, for medication
There is no compliance, and drug is psychologically also felt to dislike, while the expense of drug can make some think to spend not
It is worth, such case can lead to the further damage of health；Therefore, there is arousing brain, raising spirit, anti-inflammatory to reduce internal heat, intelligence development nourishing heart is made
Health beverages are a kind of drinks that modern people are badly in need of.
For the needs of above-mentioned present people's life, the purpose of the present invention is to provide one kind having reduce internal heat anti-inflammatory, clearing
The Tea containing traditional Chinese medicine of sharp larynx effect.
Invention content
In view of the above-mentioned problems, anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine the present invention is intended to provide one kind is reduced internal heat.
The invention is realized by the following technical scheme：
One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, is made of the raw material of following parts by weight：28 ~ 32 parts of Chinese olive, mountain chrysanthemum 6.4 ~
7 parts, 14 ~ 15 parts of dried orange peel, 17 ~ 19 parts of mulberry leaf, 14 ~ 15 parts of the sterculia seed, 15 ~ 17 parts of Siraitia grosvenorii, 6.5 ~ 7.3 parts of purple perilla, campanulaceae 14 ~
15 parts, 6 ~ 7 parts of green tea powder, 12 ~ 14 parts of rock sugar；
The green tea powder, is prepared according to the following steps：Green tea is put into polybag and is sealed, merging household freezer in into
Row freezing processing is taken out, and green tea is poured into and impregnates 25 ~ 30min in the water that temperature is 18 ~ 22 DEG C, and drainage takes out, and merging temperature is
16 ~ 20min of constant temperature frying in 66 ~ 70 DEG C of rotary frying pan takes out, and it is 1.4 ~ 1.6 times of amounts of green tea weight, quality point that weight, which is added,
Number filters to impregnate 90 ~ 100min in 64% ~ 70% ethanol solution and carrying out magnetization treatment, obtains alcohol extract and filter residue；To
It is added in filter residue after the water that weight is 8 ~ 9 times of amounts of green tea weight is boiled by fire and continues slow boiling 120 ~ 140min of infusion, filtering takes filter
Liquid obtains infusion liquid；Infusion liquid is mixed with alcohol extract, vacuum freeze drying obtains green tea powder.
As invention further embodiment：The freezing processing, cryostat under conditions of temperature is -23 ~ -21 DEG C
Handle 23 ~ 27min, with the heating rate of 0.65 ~ 0.75 DEG C/min be warming up to -4 ~ -2 DEG C continue cryostats processing 19 ~
21min；Be not only able to effectively remove the green taste of green tea and miscellaneous taste, promote the fragrance of green tea, and can effectively improve effectively at
Divide dissolution rate.
As invention further embodiment：The magnetization treatment, magnetic under conditions of magnetic field intensity is 0.32 ~ 0.34T
Change 34 ~ 38min of processing, suspends 26 ~ 28min, 30 ~ 34min of magnetization treatment under conditions of magnetic field intensity is 0.62 ~ 0.64T；Energy
The rupture of green tea cell wall is enough effectively facilitated, releasing for the active ingredients such as Green Tea Polyphenols, caffeine, lipopolysaccharides, theanine is promoted
It puts, improves its effective component extraction rate, improve resource utilization.
As invention further embodiment：A kind of anti-inflammatory of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine preparation method, specifically include with
Lower step：
（1）Mountain chrysanthemum, dried orange peel, mulberry leaf, purple perilla, campanulaceae and green tea powder are mixed into obtain mixture A, input weight is mixture A weights
In the water of 10 times of amounts of amount, continue slow boiling 110 ~ 130min of infusion after being boiled by fire, the water of 10 times of amounts of mixture A weight is added, greatly
Fire continues slow boiling 55 ~ 65min of infusion after boiling, and obtains infusion liquid A；
（2）Chinese olive, the sterculia seed and Siraitia grosvenorii are mixed into obtain mixture B, temperature is added into mixture B is for 55 ~ 60 DEG C, weight
Water 110 ~ 130min of heat-insulation soaking of 5 times of amounts of mixture B weight is added infusion liquid A and is mixed evenly, is ultrasonically treated, big fire
Continue slow boiling 40 ~ 50min of infusion after boiling, obtains infusion liquid B；
（3）Infusion liquid B is filtered and takes filtrate, the medicinal extract that proportion is 1.1 ~ 1.2 is concentrated under the conditions of 64 ~ 66 DEG C, spraying
Dry, ultramicro grinding is mixed with the rock sugar of crushing, the anti-inflammatory that must reduce internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine；
（4）Vacuum bagged, every bag of 6g sterilize, and labelling obtains finished product.
As invention further embodiment：Step（2）The supersound process is 110 ~ 120W, frequency 185 in power
23 ~ 27min is ultrasonically treated under conditions of ~ 190kHz, it is ultrasonic under conditions of power is 160 ~ 170W, frequency is 240 ~ 245kHz
Handle 32 ~ 36min；Effectively facilitate Chinese medicine cell disappear crystalline substance, swelling, broken wall, membrane tissue transmission ability improve so that Chinese medicine with it is molten
The contact frequency of agent increases substantially so that traditional Chinese medicine extyaction is more abundant, and further promotes green tea powder and Chinese medicine
The fusion and effect of active ingredient, and effective effective component is protected, the generation of oxidative phenomena is effectively avoided, to have
Effect promotes the double raising of drug effect, improves effective component of chinese medicine utilization rate, improves drug effect.
As invention further embodiment：Chinese olive used in the present invention, mountain chrysanthemum, dried orange peel, mulberry leaf, the sterculia seed, arhat
The content of fruit, purple perilla and campanulaceae is in terms of dry weight weight.
Pharmacology explanation：
Chinese olive：Containing protein 1.2%, fat 1.09%, carbohydrate 12%, calcium 0.204%, phosphorus 0.046%, iron 0.0014% is anti-bad
Hematic acid 0.02%；Its is sweet in flavor, sour, puckery, mild-natured；Function removing heat from the lung and relieving sorethroat, promote the production of body fluid to quench thirst, detoxify, disappear fishbone；Suitable for cough phlegm blood, pharynx
Larynx swelling and pain, hot summer weather polydipsia, drunk, fish and crab poisoning, fish-bone fishbone larynx person.
Mountain chrysanthemum：It is clearing heat and detoxicating, detumescence, to staphylococcus aureus, corynebacterium diphtheriae, streptococcus, Pseudomonas aeruginosa, puncture disease bar
Bacterium, influenza virus have inhibiting effect.
Dried orange peel：Warm-natured, acrid flavour is bitter, returns spleen, lung channel；With ventilation invigorating the spleen, eliminating dampness and eliminating phlegm, the greasy lasting of solution, stopping nausea and vomiting by lowering the adverse flow of QI
Effect cures mainly the taste stagnation of the circulation of vital energy, and gastral cavity abdomen covers with, nausea and vomiting, loss of appetite, coughing with a lot of sputum, chest and diaphragm expire vexed, globus hysteriocus.
Mulberry leaf：Bitter cold eliminating heat from the lung, sweet cold and cool dry moistening lung are used for lung heat or dry-heat impairing lung, and cough phlegm is few, and color is yellow and glues
The symptoms such as thick or dry cough lacks phlegm, pharynx is itched.
The sterculia seed：It is sweet in flavor, light, cool in nature, return lung, large intestine channel；Clearing heat and moistening lung, liyan jiedu relax bowel；For lung heat sound
Mute, dry cough without phlegm, pharyngodynia with dryness, heat knot just closes, headache and hot eyes, for opening lung qi, clearing lung-heat heat.
Siraitia grosvenorii：Contain the medicinal ingredients such as mogroside, a variety of amino acid and vitamin；Cure mainly lung heat phlegm-fire cough,
Sphagitis, tonsillitis, acute gastritis, constipation etc..
Purple perilla：Property and flavor of peppery and warm；Have effects that deliver, cold dispelling, qi-regulating and battalion, the chill that cures cold, fever with aversion to cold, cough,
Asthma, fullness and oppression of chest and abdomen etc.；《Compendium of Materia Medica》It carries " during promoting the circulation of qi is wide, clear phlegm profit lung and blood, middle benefit gas, analgesic, Dingchuan, tocolysis ".
Campanulaceae：It is slightly bitter after taste is slightly sweet；There is the effects that cough-relieving apophlegmatic, facilitaing lung, apocenosis.
Green tea：Contain tea polyphenols, caffeine, lipopolysaccharides, theanine etc.；Not only have to refresh oneself and clears away heart-fire, clearing away summerheat, helps digestion
The pharmacological actions such as resolving sputum, eliminating greasiness weight-reducing, relieving restlessness that clears away heart-fire, removing toxic substances sober up, promote the production of body fluid to quench thirst, fall fire improving eyesight, stop dysentery dehumidifying, also to the modern times
Disease, such as Radiation sickness, cardiovascular and cerebrovascular diseases, cancer disease, there is certain pharmacological effect.
Rock sugar：It is sweet in flavor, mild-natured, enter lung, the spleen channel；Have the function of moistening lung, cough-relieving, clear phlegm and reduces internal heat.
Beneficial effects of the present invention：One kind provided by the invention is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, be added green tea powder with
Plurality of Chinese coordinated acts on, and effectively facilitates mutual between the release of each effective component of chinese medicine and the effective medicinal ingredient of promotion
Effect so that drug effect is double, anti-inflammatory of effectively reducing internal heat, pharynx-clearing throat-benefiting, clearing heat and detoxicating, swelling and pain relieving so that breath freshening, effectively only
Cough resolving sputum eliminates analgesia, whets the appetite, and improves resource utilization, without any side effects, and can effectively cover the difficulty of Chinese medicine
Smelling promotes the fragrant of Tea containing traditional Chinese medicine entirety, effectively facilitates gastrointestinal health, warm stomach nourishing the stomach inhibits the taste of harmful intestinal tract bacteria
It is raw, promote the proliferation of beneficial bacterium, enhance gastrointestinal tract ability, inhibit the generation of intestines problem, promotes the suction to nutriment
Receive digestion conversion ratio；Rock sugar is added, makes Tea containing traditional Chinese medicine overall taste further be promoted when brewing, effectively eliminates traditional Chinese medicine ingredients and carry
Bitter taste so that smooth in taste is fine and smooth, avoids the repulsion of drinking person.
Specific implementation mode
Illustrate the present invention with specific embodiment below, but is not limitation of the present invention.
Embodiment 1
In the embodiment of the present invention, one kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, is made of the raw material of following parts by weight：Chinese olive 28
Part, 6.4 parts of mountain chrysanthemum, 14 parts of dried orange peel, 17 parts of mulberry leaf, 14 parts of the sterculia seed, 15 parts of Siraitia grosvenorii, 6.5 parts of purple perilla, 14 ~ 15 parts of campanulaceae,
6 parts of green tea powder, 12 parts of rock sugar；
The green tea powder, is prepared according to the following steps：Green tea is put into polybag and is sealed, merging household freezer in into
Row freezing processing is taken out, and green tea is poured into the water that temperature is 18 DEG C and impregnates 25min, and drainage takes out, and merging temperature is 66 DEG C
Constant temperature frying 16min in rotary frying pan takes out, and it is that the ethyl alcohol that green tea weight 1.4 times of amounts, mass fractions are 64% is molten that weight, which is added,
90min is impregnated in liquid and carries out magnetization treatment, is filtered, is obtained alcohol extract and filter residue；It is green tea weight that weight is added into filter residue
The water of 8 times of amounts of amount continues slow boiling infusion 120min after being boiled by fire, filtering takes filtrate, obtains infusion liquid；Infusion liquid and ethyl alcohol are soaked
Extract mixes, and vacuum freeze drying obtains green tea powder.
As invention further embodiment：The freezing processing, cryostat is handled under conditions of temperature is -23 DEG C
23min is warming up to -4 DEG C with the heating rate of 0.65 DEG C/min and continues cryostat processing 19min；It is not only able to effectively remove
The green taste and miscellaneous taste of green tea, promote the fragrance of green tea, and can effectively improve active ingredient dissolution rate.
As invention further embodiment：The magnetization treatment, magnetization treatment under conditions of magnetic field intensity is 0.32T
34min suspends 26min, magnetization treatment 30min under conditions of magnetic field intensity is 0.62T；Green tea cell wall can be effectively facilitated
Rupture, promote the release of Green Tea Polyphenols, caffeine, lipopolysaccharides, the active ingredients such as theanine, improve the extraction of its active ingredient
Rate improves resource utilization.
As invention further embodiment：A kind of anti-inflammatory of reducing internal heat, pharynx-clearing throat-benefiting preparation method, specifically include following step
Suddenly：
（1）Mountain chrysanthemum, dried orange peel, mulberry leaf, purple perilla, campanulaceae and green tea powder are mixed into obtain mixture A, input weight is mixture A weights
In the water of 10 times of amounts of amount, continue slow boiling infusion 110min after being boiled by fire, the water of 10 times of amounts of mixture A weight is added, big fire is boiled
Continue slow boiling infusion 55min after boiling, obtains infusion liquid A；
（2）Chinese olive, the sterculia seed and Siraitia grosvenorii are mixed into obtain mixture B, addition temperature is 55 DEG C into mixture B, weight is mixed
Water 110 ~ the 130min of heat-insulation soaking for closing material B 5 times of amounts of weight is added infusion liquid A and is mixed evenly, is ultrasonically treated, and big fire is boiled
Continue slow boiling infusion 40min after boiling, obtains infusion liquid B；
（3）Infusion liquid B is filtered and takes filtrate, the medicinal extract that proportion is 1.1 is concentrated under the conditions of 64 DEG C, is spray-dried, surpasses
Crushing of Ultrafine is mixed with the rock sugar of crushing, the anti-inflammatory that must reduce internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine；
（4）Vacuum bagged, every bag of 6g sterilize, and labelling obtains finished product.
As invention further embodiment：Step（2）The supersound process, power be 110W, frequency 185kHz
Under conditions of be ultrasonically treated 23min, be ultrasonically treated 32min under conditions of power is 160W, frequency is 240kHz；.
Embodiment 2
In the embodiment of the present invention, one kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, is made of the raw material of following parts by weight：Chinese olive 30
Part, 6.7 parts of mountain chrysanthemum, 14.5 parts of dried orange peel, 18 parts of mulberry leaf, 14.5 parts of the sterculia seed, 16 parts of Siraitia grosvenorii, 6.9 parts of purple perilla, campanulaceae 14.5
Part, 6.5 parts of green tea powder, 13 parts of rock sugar；
The green tea powder, is prepared according to the following steps：Green tea is put into polybag and is sealed, merging household freezer in into
Row freezing processing is taken out, and green tea is poured into and impregnates 25 ~ 30min in the water that temperature is 20 DEG C, and drainage takes out, and merging temperature is 68
DEG C rotary frying pan in constant temperature frying 18min, take out, the second that weight is 1.5 times of green tea weight amount, mass fractions are 67% be added
Alcohol solution for soaking 95min simultaneously carries out magnetization treatment, and filtering obtains alcohol extract and filter residue；It is green that weight is added into filter residue
The water of 8.5 times of amounts of tea weight continues slow boiling infusion 130min after being boiled by fire, filtering takes filtrate, obtains infusion liquid；By infusion liquid with
Alcohol extract mixes, and vacuum freeze drying obtains green tea powder.
As invention further embodiment：The freezing processing, cryostat is handled under conditions of temperature is -22 DEG C
25min is warming up to -3 DEG C with the heating rate of 0.7 DEG C/min and continues cryostat processing 20min；It is not only able to effectively remove green
The green taste and miscellaneous taste of tea, promote the fragrance of green tea, and can effectively improve active ingredient dissolution rate.
As invention further embodiment：The magnetization treatment, magnetization treatment under conditions of magnetic field intensity is 0.33T
36min suspends 27min, magnetization treatment 32min under conditions of magnetic field intensity is 0.63T；Green tea cell wall can be effectively facilitated
Rupture, promote the release of Green Tea Polyphenols, caffeine, lipopolysaccharides, the active ingredients such as theanine, improve the extraction of its active ingredient
Rate improves resource utilization.
As invention further embodiment：A kind of anti-inflammatory of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine preparation method, specifically include with
Lower step：
（1）Mountain chrysanthemum, dried orange peel, mulberry leaf, purple perilla, campanulaceae and green tea powder are mixed into obtain mixture A, input weight is mixture A weights
In the water of 10 times of amounts of amount, continue slow boiling infusion 120min after being boiled by fire, the water of 10 times of amounts of mixture A weight is added, big fire is boiled
Continue slow boiling infusion 60min after boiling, obtains infusion liquid A；
（2）Chinese olive, the sterculia seed and Siraitia grosvenorii are mixed into obtain mixture B, addition temperature is 58 DEG C into mixture B, weight is mixed
The water heat-insulation soaking 120min for closing material B 5 times of amounts of weight is added infusion liquid A and is mixed evenly, is ultrasonically treated, after being boiled by fire
Continue slow boiling infusion 45min, obtains infusion liquid B；
（3）Infusion liquid B is filtered and takes filtrate, the medicinal extract that proportion is 1.15 is concentrated under the conditions of 65 DEG C, is spray-dried, surpasses
Crushing of Ultrafine is mixed with the rock sugar of crushing, the anti-inflammatory that must reduce internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine；
（4）Vacuum bagged, every bag of 6g sterilize, and labelling obtains finished product.
As invention further embodiment：Step（2）The supersound process, power be 115W, frequency 188kHz
Under conditions of be ultrasonically treated 25min, be ultrasonically treated 34min under conditions of power is 165W, frequency is 243kHz；.
Embodiment 3
In the embodiment of the present invention, one kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, is made of the raw material of following parts by weight：Chinese olive 32
Part, 7 parts of mountain chrysanthemum, 15 parts of dried orange peel, 19 parts of mulberry leaf, 15 parts of the sterculia seed, 17 parts of Siraitia grosvenorii, 7.3 parts of purple perilla, 15 parts of campanulaceae, green tea
7 parts of powder, 14 parts of rock sugar；
The green tea powder, is prepared according to the following steps：Green tea is put into polybag and is sealed, merging household freezer in into
Row freezing processing is taken out, and green tea is poured into the water that temperature is 22 DEG C and impregnates 30min, and drainage takes out, and merging temperature is 70 DEG C
Constant temperature frying 20min in rotary frying pan takes out, and it is that the ethyl alcohol that green tea weight 1.6 times of amounts, mass fractions are 70% is molten that weight, which is added,
100min is impregnated in liquid and carries out magnetization treatment, is filtered, is obtained alcohol extract and filter residue；It is green tea weight that weight is added into filter residue
The water of 9 times of amounts of amount continues slow boiling infusion 140min after being boiled by fire, filtering takes filtrate, obtains infusion liquid；Infusion liquid and ethyl alcohol are soaked
Extract mixes, and vacuum freeze drying obtains green tea powder.
As invention further embodiment：The freezing processing, cryostat is handled under conditions of temperature is -21 DEG C
27min is warming up to -2 DEG C with the heating rate of 0.75 DEG C/min and continues cryostat processing 21min；It is not only able to effectively remove
The green taste and miscellaneous taste of green tea, promote the fragrance of green tea, and can effectively improve active ingredient dissolution rate.
As invention further embodiment：The magnetization treatment, magnetization treatment under conditions of magnetic field intensity is 0.34T
38min suspends 28min, magnetization treatment 34min under conditions of magnetic field intensity is 0.64T；Green tea cell wall can be effectively facilitated
Rupture, promote the release of Green Tea Polyphenols, caffeine, lipopolysaccharides, the active ingredients such as theanine, improve the extraction of its active ingredient
Rate improves resource utilization.
As invention further embodiment：A kind of anti-inflammatory of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine preparation method, specifically include with
Lower step：
（1）Mountain chrysanthemum, dried orange peel, mulberry leaf, purple perilla, campanulaceae and green tea powder are mixed into obtain mixture A, input weight is mixture A weights
In the water of 10 times of amounts of amount, continue slow boiling infusion 130min after being boiled by fire, the water of 10 times of amounts of mixture A weight is added, big fire is boiled
Continue slow boiling after boiling and endure 65min, obtains infusion liquid A；
（2）Chinese olive, the sterculia seed and Siraitia grosvenorii are mixed into obtain mixture B, temperature is added into mixture B is for 55 ~ 60 DEG C, weight
The water heat-insulation soaking 130min of 5 times of amounts of mixture B weight is added infusion liquid A and is mixed evenly, is ultrasonically treated, is boiled by fire
Continue slow boiling infusion 50min afterwards, obtains infusion liquid B；
（3）Infusion liquid B is filtered and takes filtrate, the medicinal extract that proportion is 1.2 is concentrated under the conditions of 66 DEG C, is spray-dried, surpasses
Crushing of Ultrafine is mixed with the rock sugar of crushing, the anti-inflammatory that must reduce internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine；
（4）Vacuum bagged, every bag of 6g sterilize, and labelling obtains finished product.
As invention further embodiment：Step（2）The supersound process, power be 120W, frequency 190kHz
Under conditions of be ultrasonically treated 27min, be ultrasonically treated 36min under conditions of power is 170W, frequency is 245kHz；.
Comparative example 1
One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, and difference lies in the raw material components are different, are added without with embodiment 1
Green tea powder, other conditions all same.
Comparative example 2
One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, and difference lies in the raw material components are different, are added without with embodiment 1
Dried orange peel and mulberry leaf, other conditions all same.
Comparative example 3
One kind is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, and difference lies in the raw material components are different, are added without with embodiment 1
Chinese olive and mountain chrysanthemum, other conditions all same.
Experiment 1
Acute toxicity test
Experiment material：Kunming mouse, 22 ± 2g of weight, half male and half female；The embodiment of the present invention is reduced internal heat anti-inflammatory, pharynx-clearing throat-benefiting Chinese medicine
Tea is made into required for trying Chinese medicine tea liquid with distilled water；
Experiment condition：24 ~ 28 DEG C of temperature, humidity are 45% ~ 50%；
Experimental method：Animal packet：Each embodiment sets two dosage groups, every group of 10 mouse, half male and half female；It dosage and gives
Mode：Experiment sets 4640,10000mg/kg, two dosage groups, is administered using oral gavage mode, daily gavage 2 times, continuous to see
It examines 10 days；Experimental result such as table 1：
1 Mouse Acute Toxicity experimental result of table
| The 4640mg/kg dosage group death rates（%） | The 10000mg/kg dosage group death rates（%） | |
| Embodiment 1 | 0 | 0 |
| Embodiment 2 | 0 | 0 |
| Embodiment 3 | 0 | 0 |
As shown in Table 1, have no that poisoning symptom and death condition occurs in experiment mice in the observation period, the present invention is reduced internal heat anti-inflammatory, clearing
Sharp larynx Tea containing traditional Chinese medicine is more than 10000mg/kg to the LD50 values of mouse, and according to acute toxicity grading criteria, acute toxicity belongs to real
Border non-toxic type.
Experiment 2
Reduce internal heat anti-inflammatory, pharynx-clearing throat-benefiting experiment：Randomly choose sphagitis patient 80 of the age at 16 ~ 60 years old（Men and women is fifty-fifty）, put down
It is divided into 4 groups, every group 20（Men and women is fifty-fifty）, respectively brew that clean fiery anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine primary sooner or later daily, every time
One bag, detect its anti-inflammatory of reducing internal heat, pharynx-clearing throat-benefiting effect；Curative effect determinate standard：Through treat 3d within cough and expectoration, throat pain,
The clinical symptoms such as throat hyperemia and drying completely disappear, and each vital sign is in normal range (NR), and the state of mind is good, and 7
Without recurrence in it, that is, judge clinical treatment recovery from illness；It is congested and dry through treating cough and expectoration, throat pain, throat within 3 ~ 5d
Etc. clinical symptoms be obviously improved, each vital sign gradually approaches normal range (NR), that is, judge clinical treatment it is effective；Through treating medication
The clinical symptoms such as 3 ~ 5d cough and expectorations, throat pain, throat hyperemia and drying are without there is any improvement sign or even the state of an illness
Development judges that clinical treatment is invalid；Experimental result such as table 2：
The anti-inflammatory of reducing internal heat of 2 embodiment and comparative example of table, pharynx-clearing throat-benefiting Experimental comparison results
| Cure rate（%） | It is efficient（%） | Inefficiency（%） | |
| Embodiment 1 | 95 | 5 | 0 |
| Comparative example 1 | 0 | 40 | 60 |
| Comparative example 2 | 5 | 50 | 45 |
| Comparative example 3 | 0 | 50 | 50 |
As shown in Table 2, anti-inflammatory of reducing internal heat of the invention, the anti-inflammatory of reducing internal heat of pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, pharynx-clearing throat-benefiting significant effect.
Claims (5)
- Anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine 1. one kind is reduced internal heat, which is characterized in that be made of the raw material of following parts by weight：Chinese olive 28 ~ 32 Part, 6.4 ~ 7 parts of mountain chrysanthemum, 14 ~ 15 parts of dried orange peel, 17 ~ 19 parts of mulberry leaf, 14 ~ 15 parts of the sterculia seed, 15 ~ 17 parts of Siraitia grosvenorii, purple perilla 6.5 ~ 7.3 parts, 14 ~ 15 parts of campanulaceae, 6 ~ 7 parts of green tea powder, 12 ~ 14 parts of rock sugar；The green tea powder, is prepared according to the following steps：Green tea is put into polybag and is sealed, merging household freezer in into Row freezing processing is taken out, and green tea is poured into and impregnates 25 ~ 30min in the water that temperature is 18 ~ 22 DEG C, and drainage takes out, and merging temperature is 16 ~ 20min of constant temperature frying in 66 ~ 70 DEG C of rotary frying pan takes out, and it is 1.4 ~ 1.6 times of amounts of green tea weight, quality point that weight, which is added, Number filters to impregnate 90 ~ 100min in 64% ~ 70% ethanol solution and carrying out magnetization treatment, obtains alcohol extract and filter residue；To It is added in filter residue after the water that weight is 8 ~ 9 times of amounts of green tea weight is boiled by fire and continues slow boiling 120 ~ 140min of infusion, filtering takes filter Liquid obtains infusion liquid；Infusion liquid is mixed with alcohol extract, vacuum freeze drying obtains green tea powder.
- 2. anti-inflammatory according to claim 1 of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, which is characterized in that the freezing processing, Cryostat handles 23 ~ 27min under conditions of temperature is -23 ~ -21 DEG C, is heated up with the heating rate of 0.65 ~ 0.75 DEG C/min Continue cryostat to -4 ~ -2 DEG C and handles 19 ~ 21min.
- 3. anti-inflammatory according to claim 1 of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, which is characterized in that the magnetization treatment, Magnetic field intensity be 0.32 ~ 0.34T under conditions of 34 ~ 38min of magnetization treatment, suspend 26 ~ 28min, magnetic field intensity be 0.62 ~ 30 ~ 34min of magnetization treatment under conditions of 0.64T.
- 4. according to claim 1 ~ 3 any one of them reduce internal heat anti-inflammatory, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine preparation method, feature exists In specifically including following steps：（1）Mountain chrysanthemum, dried orange peel, mulberry leaf, purple perilla, campanulaceae and green tea powder are mixed into obtain mixture A, input weight is mixture A weights In the water of 10 times of amounts of amount, continue slow boiling 110 ~ 130min of infusion after being boiled by fire, the water of 10 times of amounts of mixture A weight is added, greatly Fire continues slow boiling 55 ~ 65min of infusion after boiling, and obtains infusion liquid A；（2）Chinese olive, the sterculia seed and Siraitia grosvenorii are mixed into obtain mixture B, temperature is added into mixture B is for 55 ~ 60 DEG C, weight Water 110 ~ 130min of heat-insulation soaking of 5 times of amounts of mixture B weight is added infusion liquid A and is mixed evenly, is ultrasonically treated, big fire Continue slow boiling 40 ~ 50min of infusion after boiling, obtains infusion liquid B；（3）Infusion liquid B is filtered and takes filtrate, the medicinal extract that proportion is 1.1 ~ 1.2 is concentrated under the conditions of 64 ~ 66 DEG C, spraying Dry, ultramicro grinding is mixed with the rock sugar of crushing, the anti-inflammatory that must reduce internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine；（4）Vacuum bagged, every bag of 6g sterilize, and labelling obtains finished product.
- 5. the preparation method of anti-inflammatory according to claim 4 of reducing internal heat, pharynx-clearing throat-benefiting Tea containing traditional Chinese medicine, which is characterized in that step（2） The supersound process is ultrasonically treated 23 ~ 27min, in work(under conditions of power is 110 ~ 120W, frequency is 185 ~ 190kHz 32 ~ 36min is ultrasonically treated under conditions of rate is 160 ~ 170W, frequency is 240 ~ 245kHz.
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