CN108641262A - 一种隐形眼镜材料及其制备 - Google Patents
一种隐形眼镜材料及其制备 Download PDFInfo
- Publication number
- CN108641262A CN108641262A CN201810407401.7A CN201810407401A CN108641262A CN 108641262 A CN108641262 A CN 108641262A CN 201810407401 A CN201810407401 A CN 201810407401A CN 108641262 A CN108641262 A CN 108641262A
- Authority
- CN
- China
- Prior art keywords
- sheet
- contact lens
- polymer
- cellulosic materials
- lens material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 61
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 229920000642 polymer Polymers 0.000 claims abstract description 38
- 239000011159 matrix material Substances 0.000 claims abstract description 32
- 239000002088 nanocapsule Substances 0.000 claims abstract description 28
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000000017 hydrogel Substances 0.000 claims abstract description 9
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
- 239000001301 oxygen Substances 0.000 claims abstract description 9
- 238000006243 chemical reaction Methods 0.000 claims abstract description 3
- 239000003431 cross linking reagent Substances 0.000 claims description 21
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical group COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 12
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 10
- 239000000178 monomer Substances 0.000 claims description 9
- 229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 claims description 8
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 8
- 239000000835 fiber Substances 0.000 claims description 5
- 229960002163 hydrogen peroxide Drugs 0.000 claims description 5
- VOZRXNHHFUQHIL-UHFFFAOYSA-N glycidyl methacrylate Chemical compound CC(=C)C(=O)OCC1CO1 VOZRXNHHFUQHIL-UHFFFAOYSA-N 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 2
- 229920002101 Chitin Polymers 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims description 2
- 235000007164 Oryza sativa Nutrition 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 239000003292 glue Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 2
- 235000009566 rice Nutrition 0.000 claims description 2
- 235000010413 sodium alginate Nutrition 0.000 claims description 2
- 229940005550 sodium alginate Drugs 0.000 claims description 2
- 239000000661 sodium alginate Substances 0.000 claims description 2
- -1 Ethenyl pyrrolidone Ketone Chemical class 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000004626 polylactic acid Substances 0.000 claims 1
- 230000035699 permeability Effects 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000000034 method Methods 0.000 description 3
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 239000002657 fibrous material Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical group FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 description 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Natural products OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Substances CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000001491 myopia Diseases 0.000 description 1
- 239000008055 phosphate buffer solution Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/46—Polymerisation initiated by wave energy or particle radiation
- C08F2/48—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/14—Methyl esters, e.g. methyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
- C08F226/10—N-Vinyl-pyrrolidone
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers
- C08J2339/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
- C08J2339/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2401/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2401/02—Cellulose; Modified cellulose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
- C08J2405/04—Alginic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
- C08J2405/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2467/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2467/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2489/00—Characterised by the use of proteins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Polymerisation Methods In General (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Graft Or Block Polymers (AREA)
Abstract
本发明公开了一种隐形眼镜材料及其制备。所述隐形眼镜材料包括基体,分散于所述基体中的聚合物纳米胶囊和片状纤维素材料;所述基体为水凝胶,所述聚合物纳米胶囊能够通过化学反应释放氧气。本发明的隐形眼镜材料通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料,使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比,片状纤维素材料具有生物相容性。
Description
技术领域
本发明涉及眼镜技术领域,具体涉及一种隐形眼镜材料及其制备。
背景技术
随着人们对于美丽的追求,越来越多的近视患者会选择佩戴隐形眼镜。隐形眼镜基本上分类为软质型和硬质型眼镜。其中,软质隐形眼镜通常分为水凝胶隐形眼镜和非水凝胶隐形眼镜。常规的软质水凝胶隐形眼镜通常由亲水性单体(例如甲基丙烯酸羟基乙酯、N-乙烯基吡咯烷酮等)的共聚物组成,且可通过车床切割方法、旋转浇筑方法、注塑成型方法或其组合,之后通过在生理盐水和/或磷酸盐缓冲溶液中进行溶胀处理以获得含水量20%-80%(质量百分比)的眼镜而制成。
随着人们安全意识的增强,对于隐形眼镜的性能要求也越来越高,例如透氧性、抗紫外性、生物相容性。
发明内容
基于以上背景技术,本发明提供一种隐形眼镜材料及其制备,通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料,使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比,片状纤维素材料具有生物相容性。
为了实现上述目的,本发明采用以下技术方案:
一种隐形眼镜材料,包括基体,分散于所述基体中的聚合物纳米胶囊和片状纤维素材料;所述基体为水凝胶,所述聚合物纳米胶囊能够通过化学反应释放氧气。
优选地,所述聚合物纳米胶囊包括过氧化氢溶液及包裹所述过氧化氢溶液的壁材。
更优选地,所述壁材选自甲壳素、聚乳酸羟基乙酸共聚物、海藻酸钠或明胶。所选壁材为可分解的高分子,壁材在基体中缓慢分解而释放出过氧化氢溶液,过氧化氢自行分解并释放出氧气和水,提高隐形眼镜的透氧性。
优选地,所述片状纤维素材料粒径大小为10-40微米,厚度1-5微米。所述片状纤维素材料能够阻断UVA 320-400 nm、UVB 280-320 nm范围紫外线的透过,使得隐形眼镜具有抗紫外线性能。
本发明还提供上述隐形眼镜材料的制备方法,包括以下步骤:
将片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂混合,在紫外光照射下,亲水性单体和水合聚合物发生聚合反应,形成基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。
优选地,所述亲水性单体选自N-乙烯基吡咯烷酮、甲基丙烯酸缩水甘油酯或N,N-二甲基丙烯酰胺;所述水合聚合物选自甲基丙烯酸甲酯或甲基丙烯酸羟乙酯。
优选地,所述片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂的质量比为(0.01-0.05):(0.001-0.01): 1 : 1:(0.01-0.1):(0.001-0.01)。
本发明的有益效果
本发明公开的隐形眼镜材料,通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料,使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比,片状纤维素材料具有生物相容性。
具体实施方式
下面通过实施例对本发明进行具体描述,有必要在此指出的是本实施例只用于对本发明进行进一步说明,不能理解为对本发明保护范围的限制,该领域的技术熟练人员可以根据以上发明的内容做出一些非本质的改进和调整。在不冲突的情况下,本发明中的实施例及实施例中的特征可以相互组合。以下实施例中的光引发剂为 Irgacure-1173,交联剂为二甲基丙烯酸乙二醇酯。
实施案例1
将片状纤维素材料、聚合物纳米胶囊、N-乙烯基吡咯烷酮、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比(0.01 : 0.01 : 1 : 1: 0.01: 0.001)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为57%。
实施案例2
将片状纤维素材料、聚合物纳米胶囊、N-乙烯基吡咯烷酮、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比(0.02 : 0.005 : 1 : 1: 0.05: 0.005)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为:53%。
实施案例3
将片状纤维素材料、聚合物纳米胶囊、甲基丙烯酸缩水甘油酯、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比(0.02 : 0.005 : 1 : 1: 0.05: 0.005)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为54%。
实施案例4
将片状纤维素材料、聚合物纳米胶囊、甲基丙烯酸缩水甘油酯、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比(0.02 : 0.005 : 1 : 1: 0.05: 0.005)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为52%。
实施案例5
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比(0.03 : 0.001 : 1 : 1: 0.1: 0.01)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为42%。
实施案例6
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比(0.04 : 0.001 : 1 : 1: 0.1: 0.01)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为30%。
实施案例7
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比(0.05 : 0.001 : 1 : 1: 0.1: 0.01)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为25%。
对比案例1
将聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比(0.001 : 1 : 1: 0.1: 0.01)混合,在紫外光照射下,N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应,形成水凝胶基体,所述聚合物纳米胶囊分散于所述基体中。紫外线透过率为82%。由此数据可看出,由于加入的片状纤维素材料能够阻断UVA 320-400 nm、UVB 280-320 nm范围紫外线的透过,使得隐形眼镜具有抗紫外线性能。
由以上实施例1-7所得隐形眼镜材料的紫外线透过率数据可看出,随着片状纤维素材料的含量的升高,抗紫外线的效果越好,但是从可见光的透光性来看,当片状纤维素材料的质量比达到0.03时,会逐渐影响隐形眼镜的清晰度,因此片状纤维素材料的质量比优选地为0.01-0.03。
Claims (7)
1.一种隐形眼镜材料,其特征在于,包括基体,分散于所述基体中的聚合物纳米胶囊和片状纤维素材料;所述基体为水凝胶,所述聚合物纳米胶囊能够通过化学反应释放氧气。
2.根据权利要求1所述的隐形眼镜材料,其特征在于,所述聚合物纳米胶囊包括过氧化氢溶液及包裹所述过氧化氢溶液的壁材。
3.根据权利要求2所述的隐形眼镜材料,其特征在于,所述壁材选自甲壳素、聚乳酸羟基乙酸共聚物、海藻酸钠或明胶。
4.根据权利要求1所述的隐形眼镜材料,其特征在于,所述片状纤维素材料粒径大小为10-40微米,厚度1-5微米。
5.一种权利要求1-4任一所述的隐形眼镜材料的制备方法,其特征在于,包括以下步骤:
将片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂混合,在紫外光照射下,亲水性单体和水合聚合物发生聚合反应,形成基体,所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。
6.根据权利要求5所述的制备方法,其特征在于,所述亲水性单体选自N-乙烯基吡咯烷酮、甲基丙烯酸缩水甘油酯或N,N-二甲基丙烯酰胺;所述水合聚合物选自甲基丙烯酸甲酯或甲基丙烯酸羟乙酯。
7.根据权利要求5所述的制备方法,其特征在于,所述片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂的质量比为(0.01-0.05):(0.001-0.01): 1 : 1:(0.01-0.1):(0.001-0.01)。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810407401.7A CN108641262A (zh) | 2018-05-02 | 2018-05-02 | 一种隐形眼镜材料及其制备 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810407401.7A CN108641262A (zh) | 2018-05-02 | 2018-05-02 | 一种隐形眼镜材料及其制备 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108641262A true CN108641262A (zh) | 2018-10-12 |
Family
ID=63748439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810407401.7A Pending CN108641262A (zh) | 2018-05-02 | 2018-05-02 | 一种隐形眼镜材料及其制备 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108641262A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112316219A (zh) * | 2020-09-29 | 2021-02-05 | 浙江大学 | 一种防粘连水凝胶-蚕丝支架复合膜及其制备与应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104974357A (zh) * | 2014-04-10 | 2015-10-14 | 中国科学院理化技术研究所 | 抗紫外线片状纤维素材料及其制备方法和应用 |
CN106773120A (zh) * | 2015-11-25 | 2017-05-31 | 鸿富锦精密工业(深圳)有限公司 | 隐形眼镜镜片材料及隐形眼镜镜片 |
-
2018
- 2018-05-02 CN CN201810407401.7A patent/CN108641262A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104974357A (zh) * | 2014-04-10 | 2015-10-14 | 中国科学院理化技术研究所 | 抗紫外线片状纤维素材料及其制备方法和应用 |
CN106773120A (zh) * | 2015-11-25 | 2017-05-31 | 鸿富锦精密工业(深圳)有限公司 | 隐形眼镜镜片材料及隐形眼镜镜片 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112316219A (zh) * | 2020-09-29 | 2021-02-05 | 浙江大学 | 一种防粘连水凝胶-蚕丝支架复合膜及其制备与应用 |
CN112316219B (zh) * | 2020-09-29 | 2022-05-10 | 浙江大学 | 一种防粘连水凝胶-蚕丝支架复合膜及其制备与应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106674852B (zh) | 一种防蓝光镜片及其树脂原料 | |
JP6486457B2 (ja) | 湿潤性表面を有するハイドロゲルコンタクトレンズ及びその製造方法 | |
DK1782845T3 (da) | Knoglecement og röntgen-kontraststof og fremgangsmåde til fremstilling heraf | |
JPS58500287A (ja) | 親水性水膨潤性重合組成物 | |
JP2019510265A (ja) | 青色光遮断ソフトコンタクトレンズの製造方法及びこれを用いて製造されたソフトコンタクトレンズ | |
JPS6162537A (ja) | 歯科用重合性組成物 | |
JP6628396B2 (ja) | 3dプリンタ用ゲル材料 | |
KR101833612B1 (ko) | 다량의 유기계 자외선 차단제를 함유하는 고분자 복합입자 및 그의 제조방법 | |
CN111171342B (zh) | 一种高强韧自修复荧光双网络水凝胶及其制备方法 | |
CN205953912U (zh) | 一种复合型oca光学胶 | |
KR20180037355A (ko) | 3d 프린터용 하이드로겔 잉크 조성물 및 이를 이용한 하이드로겔 구조체의 제조 방법 | |
CN108641262A (zh) | 一种隐形眼镜材料及其制备 | |
CN106810640A (zh) | 水胶组成物及水胶镜片 | |
CN108976350B (zh) | 一种仿生关节软骨聚离子络合物水凝胶及其制备方法 | |
JP4879554B2 (ja) | ポストインプリント可能なヒドロゲル材料の製造方法 | |
Somya et al. | Interpenetrating polymer network-based drug delivery systems: emerging applications and recent patents | |
KR102199118B1 (ko) | 청색광 차단 조성물 및 이를 이용한 청색광 차단 콘텍트렌즈 및 그 제조방법 | |
TWI630436B (zh) | 隱形眼鏡鏡片材料及隱形眼鏡鏡片 | |
CN101831126B (zh) | 全防紫外线抗疲劳及防恶性黑色素细胞癌光学防护材料 | |
JPH0724052A (ja) | 青視症補正用軟性眼内レンズ | |
US20200115539A1 (en) | Hydrogel-forming composition and highly transparent hydrogel prepared therefrom | |
KR101817883B1 (ko) | 상온 중합법에 의한 하이드로겔 콘택트렌즈 제조방법 | |
TWI746286B (zh) | 水膠組成物及水膠鏡片 | |
CN106773120A (zh) | 隐形眼镜镜片材料及隐形眼镜镜片 | |
CN109239944A (zh) | 能够检测眼泪中葡萄糖含量的隐形眼镜及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181012 |