CN108578646A - A kind of draft conditioning liquid with bacteriostasis efficacy - Google Patents

A kind of draft conditioning liquid with bacteriostasis efficacy Download PDF

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Publication number
CN108578646A
CN108578646A CN201810786168.8A CN201810786168A CN108578646A CN 108578646 A CN108578646 A CN 108578646A CN 201810786168 A CN201810786168 A CN 201810786168A CN 108578646 A CN108578646 A CN 108578646A
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parts
grams
draft
conditioning liquid
bacteriostasis efficacy
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段颖
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Hefei Xia Kang Agel Ecommerce Ltd
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Hefei Xia Kang Agel Ecommerce Ltd
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Abstract

The invention discloses a kind of draft conditioning liquids with bacteriostasis efficacy, are made of following parts by weight：30~40 parts of Extracted From Oil-tea-cake, 28~38 parts of Luo Xianzi, 25~35 parts of blueberry leaf, 25~35 parts of dandelion, 20~30 parts of Euglena gracilis, 19~29 parts of duckweed, 19~29 parts of curcuma zedoary, 17~27 parts of motherwort, 15~25 parts of Snakegourd Fruit, 10~20 parts of bush, 1~3 part of cationic surfactant, 35~45 parts of butanediol, it can be clearing heat and detoxicating by using a kind of draft conditioning liquid with bacteriostasis efficacy, antimicrobial antiphlogistic is antiviral, it is antipruritic, putrefaction-removing granulation-promoting, it can long-acting inhibition Escherichia coli, staphylococcus aureus and Candida albicans, and bacteriostasis rate is respectively 95.5%, 95.7% and 95.1%, and it is non-stimulated to human body.

Description

A kind of draft conditioning liquid with bacteriostasis efficacy
Technical field
The present invention relates to a kind of gynaecological applications, especially a kind of draft conditioning liquid with bacteriostasis efficacy.
Background technology
Healthy women has aerobic bacteria and anaerobic bacteria to maintain health jointly under normal circumstances, forms normal flora, works as flora Between the ecological balance be broken or formation condition is caused a disease may lead to the generation of inflammation, under normal circumstances, maintain flora flat The pH value of weighing apparatus is 3.8, can inhibit germ reproduction, the ability with self-cleaning antibacterial, but since cleaning mode is improper, abuses antibiosis Element and cause germ generate drug resistance, cause flora unbalance, just will produce inflammation, clinically common inflammatory has：Bacterial inflammation (accounting for 22%~50%) reads coccus inflammation (accounting for 17%~39%).Since the invasion generation inflammation of bacterium can give normal life Living, work brings great inconvenience, but recognizes since many people lack health problem, and health care consciousness is weak, does not recognize The importance of daily nursing, and living habit is bad, and physiological health is caused to go from bad to worse, inflammation recurrent exerbation obstinate is This, it is proposed that a kind of draft conditioning liquid with bacteriostasis efficacy is to solve the above problems.
Invention content
The purpose of the present invention is to provide a kind of draft conditioning liquids with bacteriostasis efficacy, to solve in above-mentioned background technology The problem of proposition.
To achieve the above object, the present invention provides the following technical solutions：A kind of draft conditioning liquid with bacteriostasis efficacy, by Following components forms：
Extracted From Oil-tea-cake, Luo Xianzi, blueberry leaf, dandelion, Euglena gracilis, duckweed, curcuma zedoary, motherwort, Snakegourd Fruit, bush, sun from Sub- surfactant, butanediol.
It is made of following parts by weight：
30~40 parts of Extracted From Oil-tea-cake, 28~38 parts of Luo Xianzi, 25~35 parts of blueberry leaf, 25~35 parts of dandelion, Euglena gracilis 20~30 parts, 19~29 parts of duckweed, 19~29 parts of curcuma zedoary, 17~27 parts of motherwort, 15~25 parts of Snakegourd Fruit, 10~20 parts of bush, 1~3 part of cationic surfactant, 35~45 parts of butanediol.
The cationic surfactant is dodecyl benzyl dimethyl ammonium chloride.
Include the following steps：
1) preparation of water extract of TCM：Luo Xianzi, dandelion, duckweed, motherwort, Snakegourd Fruit are crushed using medicinal herb grinder And 50 mesh sieve is crossed, and it obtains herb powder A and then mixes herb powder A with the distilled water of 15 times of volumes, it is auxiliary in ultrasonic wave It is impregnated under the conditions of helping 0.5 hour, then micro-pressure medicine decocting machine is used to decoct 2 hours, filtering and 10 times of volumes of addition into filter residue Distilled water, micro-pressure medicine decocting machine decoct 1.5 hours, filter and added into filter residue the distilled water of 5 times of volumes, and micro-pressure medicine decocting machine decocts 1 hour, filtrate three times is filtered and merged, pH value is adjusted to 7.3~7.9 by sodium bicarbonate and acetic acid, is concentrated by evaporation to phase It is 1.20~1.50 grams per cubic centimeter to density, obtains Chinese traditional medicine water extract；
2) preparation of Chinese medicine supercritical extract：Using medicinal herb grinder by Extracted From Oil-tea-cake, blueberry leaf, Euglena gracilis, curcuma zedoary, Bush crushes and crosses 40 mesh sieve, obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, It is extracted by carbon dioxide, it is 15~25 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 15~25,000,000 Pa, extraction temperature are 40~50 degrees Celsius, and extraction centrifuges after 1 hour and stays supernatant liquor, obtains Chinese medicine supercritical extract；
3) preparation of draft conditioning liquid：The Chinese traditional medicine water extract that step 1) obtains is uniformly mixed with distilled water, by step 2) The Chinese medicine supercritical extract of acquisition is uniformly mixed with butanediol, is filtered to remove residual filter residue, and cation is added into mixed liquor Surfactant is mixed using homogenizer, and pH value is adjusted to 6.8~7.8 by sodium bicarbonate and acetic acid, you can is obtained A kind of relative density is 1.20~1.60 grams of draft conditioning liquids with bacteriostasis efficacy per cubic centimeter.
Compared with prior art, the beneficial effects of the invention are as follows：The present invention using Chinese medicine as raw material there is raw material to be easy to get, match The advantages of Fang Heli, toxic side effect be small and good antimicrobial effect, the wherein main component of Extracted From Oil-tea-cake are Tea Saponin, and Tea Saponin is to white Fungal infection caused by candida albicans has certain therapeutic effect, has obvious inhibiting effect to human body various pathogens；Luo Xianzi In contain a large amount of alkaloid, grease, protein and amino acid, Luo Xianzi to Escherichia coli and staphylococcus aureus have compared with Good bacteriostasis antibiosis effect；Quercetin is mainly contained in blueberry leaf, it is effective anti-inflammatory antiviral；Dandelion can clearing heat and detoxicating be one Class broad spectrum antibiotic；Euglena gracilis is rich in abundant nutritional ingredient, and most important active constituent is Euglena polysaccharide, potent can be resisted Oxidation, antiviral removing free radical, effective protection women's health；Duckweed can inducing diaphoresis promoting eruption, dispelling wind and arresting itching is effectively relieved itch and asks Topic；Curcuma zedoary has effects that antitumor, anti-bacteria and anti-virus, can be used for treating the equal gynecological diseases of chronic cervicitis, motherwort Middle main component is stachydrine and polysaccharide, and there is removing blood stasis for promoting tissue regeneration, menstruation regulating to detoxify, be that female gynecological often uses herbal drug；Snakegourd Fruit can Clearing heat and eliminating phlegm, dissipating bind disappear carbuncle；Bush can promote blood circulation, strengthen immunity；Cationic surfactant is non-oxidizable Fungicide, the ability with broad-spectrum high efficacy sterilization algae removal；It can heat-clearing by using a kind of draft conditioning liquid with bacteriostasis efficacy Removing toxic substances, antimicrobial antiphlogistic is antiviral, antipruritic, putrefaction-removing granulation-promoting, can long-acting inhibition Escherichia coli, staphylococcus aureus and Candida albicans Bacterium, and bacteriostasis rate is respectively 95.5%, 95.7% and 95.1%, and it is non-stimulated to human body.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, right below in conjunction with the embodiment of the present invention A kind of draft conditioning liquid with bacteriostasis efficacy of the present invention is further elaborated.It should be appreciated that tool described herein Body embodiment only to explain the present invention, is not intended to limit the present invention.
Embodiment 1：Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 30 grams of Extracted From Oil-tea-cake, 28 grams of Luo Xianzi, 25 grams of blueberry leaf, 25 grams of dandelion, 20 grams of Euglena gracilis, 19 grams of duckweed, 19 grams of curcuma zedoary, benefit 17 grams of Brittle Falsepimpernel Herb, 15 grams of Snakegourd Fruit, 10 grams of bush, 1 gram of cationic surfactant, 35 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 15 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 15 megapascal, and extraction temperature is 40 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.3, and relative concentration is 1.20 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol Close uniform, be filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, using homogenizer into Row mixing, you can it is 6.8 to obtain a kind of pH value, and relative density is 1.20 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Embodiment 2：Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 32 grams of Extracted From Oil-tea-cake, 30 grams of Luo Xianzi, 27 grams of blueberry leaf, 27 grams of dandelion, 22 grams of Euglena gracilis, 21 grams of duckweed, 21 grams of curcuma zedoary, benefit 19 grams of Brittle Falsepimpernel Herb, 17 grams of Snakegourd Fruit, 12 grams of bush, 1.3 grams of cationic surfactant, 37 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 17 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 17 megapascal, and extraction temperature is 42 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.5, and relative concentration is 1.24 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol It closes uniformly, is filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, be stirred well to mixed It closes uniform, you can it is 7.1 to obtain a kind of pH value, and relative density is 1.28 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Embodiment 3：Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 34 grams of Extracted From Oil-tea-cake, 32 grams of Luo Xianzi, 29 grams of blueberry leaf, 29 grams of dandelion, 24 grams of Euglena gracilis, 23 grams of duckweed, 23 grams of curcuma zedoary, benefit 21 grams of Brittle Falsepimpernel Herb, 19 grams of Snakegourd Fruit, 14 grams of bush, 1.7 grams of cationic surfactant, 39 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 19 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 19 megapascal, and extraction temperature is 44 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.4, and relative concentration is 1.31 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol It closes uniformly, is filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, be stirred well to mixed It closes uniform, you can it is 7.3 to obtain a kind of pH value, and relative density is 1.37 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Embodiment 4：Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 38 grams of Extracted From Oil-tea-cake, 34 grams of Luo Xianzi, 33 grams of blueberry leaf, 32 grams of dandelion, 27 grams of Euglena gracilis, 27 grams of duckweed, 25 grams of curcuma zedoary, benefit 24 grams of Brittle Falsepimpernel Herb, 22 grams of Snakegourd Fruit, 20 grams of bush, 2.4 grams of cationic surfactant, 45 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 22 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 25 megapascal, and extraction temperature is 48 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.5, and relative concentration is 1.38 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol It closes uniformly, is filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, be stirred well to mixed It closes uniform, you can it is 7.5 to obtain a kind of pH value, and relative density is 1.46 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Embodiment 5：Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 36 grams of Extracted From Oil-tea-cake, 36 grams of Luo Xianzi, 31 grams of blueberry leaf, 34 grams of dandelion, 25 grams of Euglena gracilis, 25 grams of duckweed, 27 grams of curcuma zedoary, benefit 22 grams of Brittle Falsepimpernel Herb, 24 grams of Snakegourd Fruit, 17 grams of bush, 2.1 grams of cationic surfactant, 42 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 24 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 23 megapascal, and extraction temperature is 46 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.7, and relative concentration is 1.46 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol It closes uniformly, is filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, be stirred well to mixed It closes uniform, you can obtain that a kind of pH value is 7.6 and relative density is 1.53 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Embodiment 6；Draft conditioning liquid manufactured in the present embodiment with bacteriostasis efficacy is made of following raw material and its weight： 40 grams of Extracted From Oil-tea-cake, 38 grams of Luo Xianzi, 35 grams of blueberry leaf, 35 grams of dandelion, 30 grams of Euglena gracilis, 29 grams of duckweed, 29 grams of curcuma zedoary, benefit 27 grams of Brittle Falsepimpernel Herb, 25 grams of Snakegourd Fruit, 20 grams of bush, 3 grams of cationic surfactant, 45 grams of butanediol.
The Extracted From Oil-tea-cake of above-mentioned weight, blueberry leaf, Euglena gracilis, curcuma zedoary, bush are crushed using medicinal herb grinder and cross 40 Mesh sieves, and obtains herb powder B, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, passes through carbon dioxide pair It is extracted, and it is 25 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 25 megapascal, and extraction temperature is 50 degrees Celsius, extraction Supernatant liquor is stayed in centrifugation after taking 1 hour, obtains Chinese medicine supercritical extract；
PH value prepared by above-mentioned fairy maiden weight sieve, dandelion, duckweed, motherwort and Snakegourd Fruit is 7.9, and relative concentration is 1.50 grams of Chinese medicine extracts per cubic centimeter are uniformly mixed with distilled water, and above-mentioned Chinese medicine supercritical extract is mixed with butanediol It closes uniformly, is filtered to remove residual filter residue, the cationic surfactant of above-mentioned weight is added into mixed liquor, be stirred well to mixed It closes uniform, you can it is 7.8 to obtain a kind of pH value, and relative density is 1.60 grams of draft with bacteriostasis efficacy per cubic centimeter Conditioning liquid.
Efficacy validation：Detection result on probation is carried out to product prepared by Examples 1 to 6；
Test event 1：The present invention is to the bactericidal effect of Escherichia coli, staphylococcus aureus and Candida albicans, test As a result such as the following table 1：
The result shows that the embodiment of the present invention 1~6 can effectively inhibit Escherichia coli, staphylococcus aureus and Candida albicans Bacterium, and sterilizing rate reaches 90% or more, and to no skin irritation, the bactericidal effect of wherein embodiment 4 is best, to large intestine bar The sterilizing rate of bacterium, staphylococcus aureus and Candida albicans is respectively 95.5%, 95.7% and 95.1%, can effectively kill bacteria suppression Bacterium.
Test event 2：The present invention carries out Escherichia coli, staphylococcus aureus and Candida albicans 1,2,4 hour Long-acting bacteriostatic is tested, test result is as follows table 2：
The result shows that 1~6 pair of Escherichia coli of the embodiment of the present invention, staphylococcus aureus and Candida albicans have length Bacteriostasis is imitated, and bacteriostasis rate reaches 90% or more in four hours.
The above is only the embodiment of the present invention, is not intended to limit the present invention in any form, although this hair Bright disclosed above with preferred embodiment, however, it is not intended to limit the invention, any person skilled in the art, not It is detached within the scope of technical solution of the present invention, when the technology contents using the disclosure above make a little change or are modified to equivalent change The equivalent embodiment of change, as long as being without departing from technical solution of the present invention content, according to the technical essence of the invention to implementing above Any simple modification, equivalent change and modification made by example, in the range of still falling within technical solution of the present invention.

Claims (4)

1. a kind of draft conditioning liquid with bacteriostasis efficacy, it is characterised in that：It is composed of the following components：
Extracted From Oil-tea-cake, Luo Xianzi, blueberry leaf, dandelion, Euglena gracilis, duckweed, curcuma zedoary, motherwort, Snakegourd Fruit, bush, cation form Face activating agent, butanediol.
2. a kind of draft conditioning liquid with bacteriostasis efficacy as described in claim 1, it is characterised in that：By following parts by weight Composition：
30~40 parts of Extracted From Oil-tea-cake, 28~38 parts of Luo Xianzi, 25~35 parts of blueberry leaf, 25~35 parts of dandelion, Euglena gracilis 20~ 30 parts, 19~29 parts of duckweed, 19~29 parts of curcuma zedoary, 17~27 parts of motherwort, 15~25 parts of Snakegourd Fruit, 10~20 parts of bush, sun from 1~3 part of sub- surfactant, 35~45 parts of butanediol.
3. a kind of draft conditioning liquid with bacteriostasis efficacy as described in claim 1, it is characterised in that：The cationic surface Activating agent is dodecyl benzyl dimethyl ammonium chloride.
4. a kind of draft conditioning liquid with bacteriostasis efficacy as described in claim 1, it is characterised in that：Include the following steps：
1) preparation of water extract of TCM：Using medicinal herb grinder by Luo Xianzi, dandelion, duckweed, motherwort, Snakegourd Fruit crush and mistake 50 mesh sieve, and obtain herb powder A and then mix herb powder A with the distilled water of 15 times of volumes, in ultrasonic wave assistant strip It is impregnated under part 0.5 hour, then micro-pressure medicine decocting machine is used to decoct 2 hours, filter and added into filter residue the distillation of 10 times of volumes Water, micro-pressure medicine decocting machine decoct 1.5 hours, filter and added into filter residue the distilled water of 5 times of volumes, it is small that micro-pressure medicine decocting machine decocts 1 When, filtrate three times is filtered and merged, pH value is adjusted to 7.3~7.9 by sodium bicarbonate and acetic acid, is concentrated by evaporation to relatively close Degree is per cubic centimeter for 1.20~1.50 grams, obtains Chinese traditional medicine water extract；
2) preparation of Chinese medicine supercritical extract：Using medicinal herb grinder by Extracted From Oil-tea-cake, blueberry leaf, Euglena gracilis, curcuma zedoary, bush 40 mesh sieve is crushed and crossed, herb powder B is obtained, then herb powder B is positioned in supercritical carbon dioxide extracting kettle, is passed through Carbon dioxide extracts it, and it is 15~25 ls/h that carbon dioxide, which is passed through flow velocity, and extracting pressure is 15~25 megapascal, extraction It is 40~50 degrees Celsius to take temperature, and extraction centrifuges after 1 hour and stays supernatant liquor, obtains Chinese medicine supercritical extract；
3) preparation of draft conditioning liquid：The Chinese traditional medicine water extract that step 1) obtains is uniformly mixed with distilled water, step 2) is obtained Chinese medicine supercritical extract be uniformly mixed with butanediol, be filtered to remove residual filter residue, cationic surface be added into mixed liquor Activating agent is mixed using homogenizer, and pH value is adjusted to 6.8~7.8 by sodium bicarbonate and acetic acid, you can is obtained a kind of Relative density is 1.20~1.60 grams of draft conditioning liquids with bacteriostasis efficacy per cubic centimeter.
CN201810786168.8A 2018-07-17 2018-07-17 A kind of draft conditioning liquid with bacteriostasis efficacy Pending CN108578646A (en)

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