CN108524898A - It is a kind of to be used to treat drug of seborrhea and preparation method thereof - Google Patents
It is a kind of to be used to treat drug of seborrhea and preparation method thereof Download PDFInfo
- Publication number
- CN108524898A CN108524898A CN201810711332.9A CN201810711332A CN108524898A CN 108524898 A CN108524898 A CN 108524898A CN 201810711332 A CN201810711332 A CN 201810711332A CN 108524898 A CN108524898 A CN 108524898A
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- Prior art keywords
- parts
- radix
- baked
- root
- ginger
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- A61K36/9068—Zingiber, e.g. garden ginger
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Abstract
The invention discloses a kind of drugs for treating seborrhea, include the raw material of following weight:Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, moutan bark, cassia twig, ginger, evodia rutaecarpa, pinellia, Radix Ophiopogonis, donkey-hide gelatin, Radix Codonopsis, honey-fried licorice root, baked ginger, stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae, stir-baked MASSA FERMENTATA MEDICI-NALIS, the root of Dahurain angelica, Herba Cistanches, safflower, corydalis tuber, Chinese cassia tree, fennel seeds, Ramulus Taxilli, Rhizoma Atractylodis Macrocephalae, Morinda officinalis, deer horn glue, coloured malt, the root bark of white mulberry, raw oyster, campanulaceae, dried human placenta, radix paeoniae rubra, excrementum pteropi, the fruit of Chinese wolfberry, Selaginella tamariscina leaf, the fruit of glossy privet, peach kernel, radix bupleuri, Cortex Eucommiae, cattail pollen, the beneficial effects of the invention are as follows:Play nourishing lung and kidney, nourishing blood for calming endogenous wind, skin moistening and itch stopping and have degreasing, antibacterial, anti-inflammatory, the effects that improving immunity of organisms, adjusting endocrine, is calm, fundamentally solve the pathogenesis of SD, reach therapeutic effect.
Description
Technical field
The present invention is a kind of for treating drug of seborrhea and preparation method thereof.
Background technology
One kind that seborrhea (seborrheic dermatitis, SD) system is happened at seborrhea position is chronic
Papulosquamous, superficial inflammatory dermatoses.Be apt to occur in after facial nasolabial groove, geisoma, mouth week, scalp, hairline, ear and upper chest,
The abundant position of the sebaceous glands such as armpit, vulva.Clinically using erythema, the scales of skin that peel off, itch as main feature, severe one can have exudation and
Its cause of disease of secondary infection is complicated and inducement is numerous, becomes and easily diagnoses refractory chronic disease in skin disease.Because it occurs mainly in face
The exsertion parts such as face, scalp can not only influence the appearance of patient, also bring great pain to patient's body and mind.Though traditional Chinese medicine nothing
This name of disease of SD can belong to the scopes such as traditional Chinese medicine " pasta wind " according to its clinical manifestation.Chinese medicine think the cause of disease be mostly diet,
The factors such as diseases caused by external factors, internal injury lead to lung-kidney deficiency, blood-deficiency and wind-dry, and it is SD to send out.The definite cause of disease and pathogenesis of seborrhea
Not yet clear, for many years based on western medicine seborrhea, but oral drugs side effect is more, and Clinical practice is limited, is true
Protecting curative effect, usually a variety of hormone medicines are used in combination, and cause side effect increased using hormone medicine due to lack of standardization,
Thus cause curative compliance poor, seriously affects clinical efficacy.Therefore, seek a kind of good effect at present and recurrence rate is low, secondary work
It is the research tendency for treating seborrhea with few drug.The advantage of traditional Chinese medicine is more highlighted under these forms, commonly
Traditional Chinese medicine for oral administration has a decoction and pill, and decoction decocting is cumbersome, poor taste, and patient compliance is poor, and pill absorbs, markedly slow, flavour of a drug
Dose is fixed, it is difficult to reach debate disease opinion control therapeutic effect.
Invention content
The purpose of the present invention is to provide a kind of drugs and preparation method thereof for treating seborrhea, in solution
State the problem of being proposed in background technology.
To achieve the above object, the present invention provides the following technical solutions:
A kind of drug for treating seborrhea includes the raw material of following parts by weight:5-35 parts of Radix Angelicae Sinensis, 5-35 parts of Radix Paeoniae Alba,
3-17 parts of Rhizoma Chuanxiong, 3-17 parts of moutan bark, 5-25 parts of cassia twig, 5-25 parts of ginger, 3-17 parts of evodia rutaecarpa, 5-25 parts of pinellia, Radix Ophiopogonis
5-35 parts, 3-17 parts of donkey-hide gelatin, 5-25 parts of Radix Codonopsis, 5-35 parts of honey-fried licorice root, 5-25 parts of baked ginger, 5-35 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae 5-35
It is part, 5-25 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 3-17 parts of the root of Dahurain angelica, 15-45 parts of Herba Cistanches, 1-5 parts of safflower, 5-25 parts of corydalis tuber, 2-8 parts of Chinese cassia tree, small
2-8 parts of fennel, 15-45 parts of Ramulus Taxilli, 5-35 parts of Rhizoma Atractylodis Macrocephalae, 5-25 parts of Morinda officinalis, 2-8 parts of deer horn glue, 15-45 parts of coloured malt, mulberry
White 3-17 parts of skin, 15-45 parts of raw oyster, 3-17 parts of campanulaceae, 2-8 parts of dried human placenta, 3-17 parts of radix paeoniae rubra, 3-17 parts of excrementum pteropi, matrimony vine
5-35 parts sub-, 3-17 parts of Selaginella tamariscina leaf, 5-25 parts of the fruit of glossy privet, 5-25 parts of peach kernel, 3-17 parts of radix bupleuri, 5-35 parts of Cortex Eucommiae, cattail pollen 3-17
Part.
As a further solution of the present invention:The drug for treating seborrhea, including following parts by weight
Raw material:10-30 parts of Radix Angelicae Sinensis, 10-30 parts of Radix Paeoniae Alba, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of moutan bark, 10-20 parts of cassia twig, ginger 10-20
Part, 5-15 parts of evodia rutaecarpa, 10-20 parts of pinellia, Radix Ophiopogonis 10-30 part, 5-15 parts of donkey-hide gelatin, 10-20 parts of Radix Codonopsis, honey-fried licorice root 10-30
Part, 10-20 parts of baked ginger, 10-30 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 10-30 parts of fructus crataegi cuneatae, 10-20 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 5-15 parts of the root of Dahurain angelica, Herba Cistanches 20-
40 parts, 2-4 parts of safflower, 10-20 parts of corydalis tuber, 3-7 parts of Chinese cassia tree, 3-7 parts of fennel seeds, 20-40 parts of Ramulus Taxilli, 10-30 parts of Rhizoma Atractylodis Macrocephalae,
10-20 parts of Morinda officinalis, 3-7 parts of deer horn glue, 20-40 parts of coloured malt, 5-15 parts of the root bark of white mulberry, 20-40 parts of raw oyster, campanulaceae 5-15
Part, 3-7 parts of dried human placenta, 5-15 parts of radix paeoniae rubra, 5-15 parts of excrementum pteropi, 10-30 parts of the fruit of Chinese wolfberry, 5-15 parts of Selaginella tamariscina leaf, fruit of glossy privet 10-20
Part, 10-20 parts of peach kernel, 5-15 parts of radix bupleuri, 10-30 parts of Cortex Eucommiae, 5-15 parts of cattail pollen.
As further scheme of the invention:The drug for treating seborrhea, including following weight
The raw material of part:20 parts of Radix Angelicae Sinensis, 20 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, 10 parts of moutan bark, 15 parts of cassia twig, 15 parts of ginger, 10 parts of evodia rutaecarpa,
15 parts of pinellia, 20 parts of Radix Ophiopogonis, 10 parts of donkey-hide gelatin, 15 parts of Radix Codonopsis, 20 parts of honey-fried licorice root, 15 parts of baked ginger, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae 20
Part, 15 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 10 parts of the root of Dahurain angelica, 30 parts of Herba Cistanches, 3 parts of safflower, 15 parts of corydalis tuber, 5 parts of Chinese cassia tree, 5 parts of fennel seeds, Ramulus Taxilli
30 parts, 20 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Morinda officinalis, 5 parts of deer horn glue, 30 parts of coloured malt, 10 parts of the root bark of white mulberry, 30 parts of raw oyster, 10 parts of campanulaceae,
5 parts of dried human placenta, 10 parts of radix paeoniae rubra, 10 parts of excrementum pteropi, 20 parts of the fruit of Chinese wolfberry, 10 parts of Selaginella tamariscina leaf, 15 parts of the fruit of glossy privet, 5 parts of peach kernel, radix bupleuri 10
Part, 20 parts of Cortex Eucommiae, 10 parts of cattail pollen.
A kind of process for preparing medicine for treating seborrhea includes the following steps:
S1, according to above-mentioned parts by weight weigh Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, moutan bark, cassia twig, ginger, evodia rutaecarpa, pinellia, Radix Ophiopogonis,
Radix Codonopsis, honey-fried licorice root, baked ginger, stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae, stir-baked MASSA FERMENTATA MEDICI-NALIS, the root of Dahurain angelica, Herba Cistanches, safflower, corydalis tuber, fennel seeds, Ramulus Taxilli,
Rhizoma Atractylodis Macrocephalae, Morinda officinalis, coloured malt, the root bark of white mulberry, raw oyster, campanulaceae, dried human placenta, radix paeoniae rubra, excrementum pteropi, the fruit of Chinese wolfberry, Selaginella tamariscina leaf, glossy privet
Son, peach kernel, radix bupleuri, Cortex Eucommiae and cattail pollen are impregnated 12 hours using clear water;
S2 decocts the raw material after immersion, and the gained elimination dregs of a decoction are obtained liquid later;
Gained liquid in step S2 is put into pot and concentrates, and donkey-hide gelatin, Chinese cassia tree and deer horn glue is added by S3, carries out slow boiling heating;
Gained in step S3 is crossed 80 mesh and sieved 2-3 times by S4, and then small fire heating is brewed into paste again, is eventually adding honey and receives cream.
As a further solution of the present invention:In step S2, when decoction, which synchronizes, is stirred operation, and by liquid surface
Foam removes, and decocting time is 3-6 hours.
As further scheme of the invention:In step S2, the dregs of a decoction addition cold water being obtained by filtration is decocted again, is decocted and is completed
Filter off the dregs of a decoction again afterwards, liquid is mixed into previous gained liquid, and the dregs of a decoction are added cold water and decoct again, repeatedly for three times.
According to lung deficiency of the kidney void physique characteristic, treat based on invigorating spleen and soothing liver, filling liver kidney, replenishing essence blood, and comprehensive to each internal organs
It adjusts, differentiates actual situation, constitution is biased, accomplishes that bowl spares has clearly, mends without stagnant, comprehensive adjustment whole body qi and blood, negative and positive reach balance
Whole body negative and positive state.Wherein
Effect that Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong and donkey-hide gelatin have nourishing blood for calming endogenous wind antipruritic.
Rhizoma Atractylodis Macrocephalae and Radix Codonopsis have strengthening the spleen and replenishing qi, the effect of with angry blood.
Matrimony vine, Ramulus Taxilli, the fruit of glossy privet, Herba Cistanches, Cortex Eucommiae, stir-baked RHIZOMA POLYGONATI with yellow rice wine and dried human placenta, which have, mends nourishing liver and kidney, beneficial to spirit and marrow
Effect.
Evodia rutaecarpa, baked ginger, Chinese cassia tree, fennel seeds, cassia twig, Morinda officinalis and deer horn glue have it is warming channel and expelling cold, with the work(of sunization the moon
Effect.
Baked ginger, safflower, corydalis tuber, the root bark of tree peony, radix paeoniae rubra, peach kernel, cattail pollen and excrementum pteropi have effect promoting blood circulation and removing blood stasis.
Radix Ophiopogonis, the root bark of white mulberry, the root of Dahurain angelica, campanulaceae and Selaginella tamariscina leaf have effects that grow lung moisturizing beauty treatment.
There is invigorating the spleen for eliminating dampness, promoting the circulation of qi to lead stagnant effect for pinellia, fructus crataegi cuneatae, stir-baked MASSA FERMENTATA MEDICI-NALIS, coloured malt, ginger and radix bupleuri.
Honey-fried licorice root has effects that replenish qi to invigorate the spleen, emergency.
Compared with prior art, the beneficial effects of the invention are as follows:(1)By numerous drug interactions, taken orally after cream is made
Rapid decompose absorbs afterwards, play nourishing lung and kidney, nourishing blood for calming endogenous wind, skin moistening and itch stopping and have degreasing, antibacterial, it is anti-inflammatory, improve immunity of organism
Power adjusts the effects that endocrine, calmness, fundamentally solves the pathogenesis of SD, reaches therapeutic effect;(2)It is easy to by patient
Receive, there is good clinical efficacy and wide social demand, is worth clinical expansion and uses;(3)Pass through a large amount of clinical sight
It examines discovery to treat by the medicine, high efficiency is uneasy to recur, fundamentally solves the disadvantage easily recurred after nervous system disease
End.Present invention is generally directed to the treatments of seborrhea, and due to the correlation of constitution, the starting point for the treatment of is started with from constitution, also
It can be used for treating a variety of skin diseases such as chronic eczema, allergic dermatitis, acne;Primary dysmenorrhea, paramenia, amenorrhoea,
The gynecological diseases such as climacteric syndrome, infertility.
Description of the drawings
Fig. 1 is a kind of process for preparing medicine flow chart for treating seborrhea.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
Referring to Fig. 1, take 5 parts of Radix Angelicae Sinensis, 5 parts of Radix Paeoniae Alba, 3 parts of Rhizoma Chuanxiong, 3 parts of moutan bark, 5 parts of cassia twig, 5 parts of ginger, 3 parts of evodia rutaecarpa,
It is 5 parts of pinellia, 5 parts of Radix Ophiopogonis, 5 parts of Radix Codonopsis, 5 parts of honey-fried licorice root, 5 parts of baked ginger, 5 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 5 parts of fructus crataegi cuneatae, 5 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, white
3 parts of the root of Dahurian angelica, 15 parts of Herba Cistanches, 1 part of safflower, 5 parts of corydalis tuber, 2 parts of fennel seeds, 15 parts of Ramulus Taxilli, 5 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of Morinda officinalis, fry
15 parts of malt, 3 parts of the root bark of white mulberry, 15 parts of raw oyster, 3 parts of campanulaceae, 2 parts of dried human placenta, 3 parts of radix paeoniae rubra, 3 parts of excrementum pteropi, 5 parts of the fruit of Chinese wolfberry,
3 parts of Selaginella tamariscina leaf, 5 parts of the fruit of glossy privet, 5 parts of peach kernel, 3 parts of radix bupleuri, 5 parts of Cortex Eucommiae, 3 parts of cattail pollen are impregnated 12 hours using clear water;
Raw material after immersion is decocted, the gained elimination dregs of a decoction are obtained into liquid later, when decoction, which synchronizes, is stirred operation,
And remove the foam on liquid surface, decocting time is 3 hours, dregs of a decoction addition cold water will be decocted repeatedly three times repeatedly later;
Gained liquid is put into pot and is concentrated, and 3 parts of donkey-hide gelatin, 2 parts of Chinese cassia tree, 2 parts of deer horn glue is added, carries out slow boiling heating, due to
Donkey-hide gelatin, Chinese cassia tree and deer horn glue are glue class drug, are not suitable for being decocted, therefore put donkey-hide gelatin, Chinese cassia tree and deer horn glue in this step
Enter and carries out molten in pot;
Gained is crossed 80 mesh to sieve 2-3 times, then small fire heating is brewed into paste again, is eventually adding honey and receives cream.
Embodiment 2
Referring to Fig. 1, taking 35 parts of Radix Angelicae Sinensis, 35 parts of Radix Paeoniae Alba, 17 parts of Rhizoma Chuanxiong, 17 parts of moutan bark, 25 parts of cassia twig, 25 parts of ginger, Wu Zhu
17 parts of cornel, 25 parts of pinellia, 35 parts of Radix Ophiopogonis, 25 parts of Radix Codonopsis, 35 parts of honey-fried licorice root, 25 parts of baked ginger, 35 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae 35
It is part, 25 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 17 parts of the root of Dahurain angelica, 45 parts of Herba Cistanches, 5 parts of safflower, 25 parts of corydalis tuber, 8 parts of fennel seeds, 45 parts of Ramulus Taxilli, white
35 parts of art, 25 parts of Morinda officinalis, 45 parts of coloured malt, 17 parts of the root bark of white mulberry, 45 parts of raw oyster, 17 parts of campanulaceae, 8 parts of dried human placenta, radix paeoniae rubra 17
Part, 17 parts of excrementum pteropi, 35 parts of the fruit of Chinese wolfberry, 17 parts of Selaginella tamariscina leaf, 25 parts of the fruit of glossy privet, 25 parts of peach kernel, 17 parts of radix bupleuri, 35 parts of Cortex Eucommiae, Pu
It is 17 parts yellow, it is impregnated 12 hours using clear water;
Raw material after immersion is decocted, the gained elimination dregs of a decoction are obtained into liquid later, when decoction, which synchronizes, is stirred operation,
And remove the foam on liquid surface, decocting time is 6 hours, dregs of a decoction addition cold water will be decocted repeatedly three times repeatedly later;
Gained liquid is put into pot and is concentrated, and 17 parts of donkey-hide gelatin, 8 parts of Chinese cassia tree, 8 parts of deer horn glue is added, carries out slow boiling heating, due to
Donkey-hide gelatin, Chinese cassia tree and deer horn glue are glue class drug, are not suitable for being decocted, therefore put donkey-hide gelatin, Chinese cassia tree and deer horn glue in this step
Enter and carries out molten in pot;
Gained is crossed 80 mesh to sieve 2-3 times, then small fire heating is brewed into paste again, is eventually adding honey and receives cream.
Embodiment 3
Referring to Fig. 1, taking 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, 10 parts of moutan bark, 15 parts of cassia twig, 15 parts of ginger, Wu Zhu
10 parts of cornel, 15 parts of pinellia, 20 parts of Radix Ophiopogonis, 15 parts of Radix Codonopsis, 20 parts of honey-fried licorice root, 15 parts of baked ginger, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae 20
It is part, 15 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 10 parts of the root of Dahurain angelica, 30 parts of Herba Cistanches, 3 parts of safflower, 15 parts of corydalis tuber, 5 parts of fennel seeds, 30 parts of Ramulus Taxilli, white
20 parts of art, 15 parts of Morinda officinalis, 30 parts of coloured malt, 10 parts of the root bark of white mulberry, 30 parts of raw oyster, 10 parts of campanulaceae, 5 parts of dried human placenta, radix paeoniae rubra 10
Part, 10 parts of excrementum pteropi, 20 parts of the fruit of Chinese wolfberry, 10 parts of Selaginella tamariscina leaf, 15 parts of the fruit of glossy privet, 5 parts of peach kernel, 10 parts of radix bupleuri, 20 parts of Cortex Eucommiae, cattail pollen
It 10 parts, is impregnated 12 hours using clear water;
Raw material after immersion is decocted, the gained elimination dregs of a decoction are obtained into liquid later, when decoction, which synchronizes, is stirred operation,
And remove the foam on liquid surface, decocting time is 4.5 hours, dregs of a decoction addition cold water will be decocted repeatedly three times repeatedly later;
Gained liquid is put into pot and is concentrated, and 10 parts of donkey-hide gelatin, 5 parts of Chinese cassia tree, 5 parts of deer horn glue is added, carries out slow boiling heating, due to
Donkey-hide gelatin, Chinese cassia tree and deer horn glue are glue class drug, are not suitable for being decocted, therefore put donkey-hide gelatin, Chinese cassia tree and deer horn glue in this step
Enter and carries out molten in pot;
Gained is crossed 80 mesh to sieve 2-3 times, then small fire heating is brewed into paste again, is eventually adding honey and receives cream.
Implement case
(1)Case selection
The first affiliated hospital of Guangxi University of Chinese Medicine Dermatology Outpatient Department patient 100 is chosen, herbal paste group and Western medicine group are randomly divided into.
50 patients of herbal paste group take gained drug in embodiment 3, wherein man 22, female 28;It is age 20-55 Sui, average(38.56
±15.78)Year;It is -36 months March of the course of disease, average(12.45±5.07)Month;
50 patients of Western medicine group give chlorphenamine maleate piece+Vitamin B6 Tablets treatment, wherein man 27, female 23;Age 18-55
It is year, average(37.08±14.98)Year;It is -35 months March of the course of disease, average(11.45±4.25)Month.
(2)Diagnostic criteria brief introduction
Chief editor is distinguished with reference to Zhao《Clinical dermatology》The diagnostic criteria of septum reset seborrhea:A betides face;B skin lesions border
Boundary understands that form is not of uniform size, and from the beginning of for perifollicolar red little Qiu Shen, then fusion is in blocks, typical skin lesion be yellowish red color or
Pale red patch, coated with the greasy or dryness scales of skin that peel off or crust;C feels different degrees of itch;The d courses of disease are chronic, recurrent exerbation, when
Weight when light;E is more common in person between twenty and fifty.
(3)Curative effect determinate standard:
Reference《New Chinese medicine guideline of clinical investigations》The effect of evaluation criteria:It is calculated using Nimodipine method.Therapeutic index=
(Prior treatment integral-post treatment integral)/ prior treatment integral 100%;
A clinical recoveries:Cardinal symptom, sign disappear or mostly disappear, therapeutic index >=95%;
B is effective:Cardinal symptom, sign are obviously improved, 70%≤therapeutic index<95%;
C is effective:Cardinal symptom, sign are clearly better, 30%≤therapeutic index<70%;
D is invalid:Cardinal symptom, sign are not improved, even it aggravates, therapeutic index<30%.
(4)Drug application method
Herbal paste group:It gives gained drug in embodiment 3 to be treated, 2 times a day, each 20ML, warm water takes;
Western medicine group:Give+Vitamin B6 Tablets, each 20mg, 3 times/day;Oral chlorphenamine maleate piece, each 4mg, 3 times/day.
(5)Clinical treatment outcome please refers to Tables 1 and 2
The pretherapy and post-treatment cardinal symptom integral contrast of 1 two groups of table
Group | Number of cases | Before treatment | After treatment | Therapeutic index |
Western medicine group | 50 | 13.03±3.15 | 7.16±1.54*# | 0.70±0.15# |
Herbal paste group | 50 | 13.10±3.09 | 4.59±1.28*# | 0.81±0.20# |
Note:Compared with Western medicine group:*P<0.05, #P<0.01.After treatment, herbal paste group is obviously improved patient's cardinal symptom(P<
0.05), curative effect is more precisely(P<0.01).
2 two groups of pretherapy and post-treatment curative effects of table compare
Group | Number of cases | Recovery from illness | It is effective | Effectively | In vain | Total effective rate |
Western medicine group | 50 | 5 | 10 | 20 | 15 | 70% |
Herbal paste group | 50 | 18 | 22 | 7 | 3 | 94% |
Note:After treatment, it is effective compared with Western medicine group that herbal paste group treats the disease(P<0.01).
(6)Clinical case is observed
Case 1:China certain, man, 36 years old, people from Nanning, the course of disease 3 years, symptom face red spot, itch occasionally had a scales of skin that peel off, dark tongue quality,
Tongue is thin, small and wiry pulse.It examines as " seborrhea ".Oral " chlorphenamine maleate piece 4mgp.otid and Vitamin B6 Tablets
20mgp.otid " does not improve through treating the half a year state of an illness;It is treated through drug of the present invention, 30 days rear face erythema for the treatment of obviously disappear
It moves back, without itch, follow-up half a year skin of face has restored normal.
Case 2:Cao, female, 50 years old, people from Liuzhou, the course of disease 1 year, the symptom face scales of skin that peel off, itch, poor dreaminess of sleeping, stool
When it is dry when dilute, oliguresis.Pale tongue lacks tongue, deep thready pulse.Local hospital outpatient service interruption is medical, and " fat is diagnosed after improving coherence check
Property of overflowing dermatitis ", has alleviation when taking orally " chlorphenamine maleate piece 4mgp.otid and Vitamin B6 Tablets 20mgp.otid " symptom.No
It is satisfied with therapeutic effect, it is then medical to our hospital, it is treated through drug of the present invention, treatment 2 weeks the rear face scales of skin that peel offs, itch obviously subside, with
Visit 1 year no relapse.
Case 3:The Qin, man, 46 years old, people from Nanning, the course of disease 2 years, symptom face itch, the scales of skin that peel off, hair, which is dried, to fall off;
With thirsty.The red few tongue of tongue, arteries and veins are thin.It examines as " seborrhea ", oral " chlorphenamine maleate piece 4mgp.otid and dimension life
Plain B6 pieces 20mgp.otid ", symptom do not have alleviation.It is treated through drug of the present invention, treats rear face in January apparent itch, the scales of skin that peel off,
2 years no relapse of follow-up.
Case 4:Chen, female, 50 years old, people from Guilin, 5-year courses, symptom face itch, the scales of skin that peel off then added on menstrual period
Weight, hectic fever, xerophtalmia, the soreness of waist is soft, weak.Tongue is red, few tongue, deep thready pulse.It examines as " seborrhea ";Oral " maleic acid chlorobenzene
, there are alleviation in that piece 4mgp.otid and Vitamin B6 Tablets 20mgp.otid ", when symptom, are unsatisfied with therapeutic effect;Through drug of the present invention
It treats, treatment is had rosy cheeks after 2 months, and skin recovery is normally relieved, and no recurrence was observed during the follow-up period of 6 months.
Case 5:It is remaining certain, man, 49 years old, people from Nanning, course of disease June, symptom face itch, the scales of skin that peel off, double knees soreness, mesh
It is dry, dry.The red few tongue of tongue, arteries and veins are thin.It examines as " seborrhea ";Oral " chlorphenamine maleate piece 4mgp.otid and vitamin B6
Piece 20mgp.otid ", less effective.It is treated through drug of the present invention, obviously facial itch, the scales of skin that peel off obviously subtract symptom after treatment 15 days
Gently, no recurrence was observed during the follow-up period of 6 months.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Profit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims
Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiment being appreciated that.
Claims (6)
1. a kind of drug for treating seborrhea, which is characterized in that include the raw material of following parts by weight:Radix Angelicae Sinensis 5-35
Part, 5-35 parts of Radix Paeoniae Alba, 3-17 parts of Rhizoma Chuanxiong, 3-17 parts of moutan bark, 5-25 parts of cassia twig, 5-25 parts of ginger, 3-17 parts of evodia rutaecarpa, ginger half
Summer 5-25 part, Radix Ophiopogonis 5-35 part, 3-17 parts of donkey-hide gelatin, 5-25 parts of Radix Codonopsis, 5-35 parts of honey-fried licorice root, 5-25 parts of baked ginger, stir-baked RHIZOMA POLYGONATI with yellow rice wine 5-35
Part, 5-35 parts of fructus crataegi cuneatae, 5-25 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 3-17 parts of the root of Dahurain angelica, 15-45 parts of Herba Cistanches, 1-5 parts of safflower, 5-25 parts of corydalis tuber,
2-8 parts of Chinese cassia tree, 15-45 parts of Ramulus Taxilli, 5-35 parts of Rhizoma Atractylodis Macrocephalae, 5-25 parts of Morinda officinalis, 2-8 parts of deer horn glue, fries wheat at 2-8 parts of fennel seeds
15-45 parts of bud, 3-17 parts of the root bark of white mulberry, 15-45 parts of raw oyster, 3-17 parts of campanulaceae, 2-8 parts of dried human placenta, 3-17 parts of radix paeoniae rubra, excrementum pteropi
3-17 parts, 5-35 parts of the fruit of Chinese wolfberry, 3-17 parts of Selaginella tamariscina leaf, 5-25 parts of the fruit of glossy privet, 5-25 parts of peach kernel, 3-17 parts of radix bupleuri, Cortex Eucommiae 5-35
Part, 3-17 parts of cattail pollen.
2. a kind of drug for treating seborrhea according to claim 1, which is characterized in that including following weight
The raw material of part:10-30 parts of Radix Angelicae Sinensis, 10-30 parts of Radix Paeoniae Alba, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of moutan bark, 10-20 parts of cassia twig, ginger 10-
20 parts, 5-15 parts of evodia rutaecarpa, 10-20 parts of pinellia, Radix Ophiopogonis 10-30 part, 5-15 parts of donkey-hide gelatin, 10-20 parts of Radix Codonopsis, honey-fried licorice root 10-
30 parts, 10-20 parts of baked ginger, 10-30 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 10-30 parts of fructus crataegi cuneatae, 10-20 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 5-15 parts of the root of Dahurain angelica, Herba Cistanches
20-40 parts, 2-4 parts of safflower, 10-20 parts of corydalis tuber, 3-7 parts of Chinese cassia tree, 3-7 parts of fennel seeds, 20-40 parts of Ramulus Taxilli, Rhizoma Atractylodis Macrocephalae 10-30
Part, 10-20 parts of Morinda officinalis, 3-7 parts of deer horn glue, 20-40 parts of coloured malt, 5-15 parts of the root bark of white mulberry, 20-40 parts of raw oyster, campanulaceae 5-
15 parts, 3-7 parts of dried human placenta, 5-15 parts of radix paeoniae rubra, 5-15 parts of excrementum pteropi, 10-30 parts of the fruit of Chinese wolfberry, 5-15 parts of Selaginella tamariscina leaf, fruit of glossy privet 10-
20 parts, 10-20 parts of peach kernel, 5-15 parts of radix bupleuri, 10-30 parts of Cortex Eucommiae, 5-15 parts of cattail pollen.
3. a kind of drug for treating seborrhea according to claim 1, which is characterized in that including following weight
The raw material of part:20 parts of Radix Angelicae Sinensis, 20 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, 10 parts of moutan bark, 15 parts of cassia twig, 15 parts of ginger, 10 parts of evodia rutaecarpa,
15 parts of pinellia, 20 parts of Radix Ophiopogonis, 10 parts of donkey-hide gelatin, 15 parts of Radix Codonopsis, 20 parts of honey-fried licorice root, 15 parts of baked ginger, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae 20
Part, 15 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 10 parts of the root of Dahurain angelica, 30 parts of Herba Cistanches, 3 parts of safflower, 15 parts of corydalis tuber, 5 parts of Chinese cassia tree, 5 parts of fennel seeds, Ramulus Taxilli
30 parts, 20 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Morinda officinalis, 5 parts of deer horn glue, 30 parts of coloured malt, 10 parts of the root bark of white mulberry, 30 parts of raw oyster, 10 parts of campanulaceae,
5 parts of dried human placenta, 10 parts of radix paeoniae rubra, 10 parts of excrementum pteropi, 20 parts of the fruit of Chinese wolfberry, 10 parts of Selaginella tamariscina leaf, 15 parts of the fruit of glossy privet, 5 parts of peach kernel, radix bupleuri 10
Part, 20 parts of Cortex Eucommiae, 10 parts of cattail pollen.
4. a kind of process for preparing medicine as described in any one of claims 1-3 for treating seborrhea, which is characterized in that
Include the following steps:
S1, according to above-mentioned parts by weight weigh Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, moutan bark, cassia twig, ginger, evodia rutaecarpa, pinellia, Radix Ophiopogonis,
Radix Codonopsis, honey-fried licorice root, baked ginger, stir-baked RHIZOMA POLYGONATI with yellow rice wine, fructus crataegi cuneatae, stir-baked MASSA FERMENTATA MEDICI-NALIS, the root of Dahurain angelica, Herba Cistanches, safflower, corydalis tuber, fennel seeds, Ramulus Taxilli,
Rhizoma Atractylodis Macrocephalae, Morinda officinalis, coloured malt, the root bark of white mulberry, raw oyster, campanulaceae, dried human placenta, radix paeoniae rubra, excrementum pteropi, the fruit of Chinese wolfberry, Selaginella tamariscina leaf, glossy privet
Son, peach kernel, radix bupleuri, Cortex Eucommiae and cattail pollen are impregnated 12 hours using clear water;
S2 decocts the raw material after immersion, and the gained elimination dregs of a decoction are obtained liquid later;
Gained liquid in step S2 is put into pot and concentrates, and donkey-hide gelatin, Chinese cassia tree and deer horn glue is added by S3, carries out slow boiling heating;
Gained in step S3 is crossed 80 mesh and sieved 2-3 times by S4, and then small fire heating is brewed into paste again, is eventually adding honey and receives cream.
5. a kind of process for preparing medicine for treating seborrhea according to claim 4, which is characterized in that step
In S2, when decoction, which synchronizes, is stirred operation, and the foam on liquid surface is removed, and decocting time is 3-6 hours.
6. a kind of process for preparing medicine for treating seborrhea according to claim 4, which is characterized in that step
In S2, the dregs of a decoction addition cold water being obtained by filtration is decocted again, filters off the dregs of a decoction again after the completion of decocting, liquid is mixed into previous gained liquid
In, the dregs of a decoction are added cold water and decoct again, repeatedly for three times.
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