CN102000164A

CN102000164A - Traditional Chinese medicine composition for treating psoriasis and preparation method thereof

Info

Publication number: CN102000164A
Application number: CN2010105434263A
Authority: CN
Inventors: 韩亮; 魏洪莲
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-11-15
Filing date: 2010-11-15
Publication date: 2011-04-06
Anticipated expiration: 2030-11-15
Also published as: CN102000164B

Abstract

The invention discloses a traditional Chinese medicine composition for treating psoriasis. An oral administration medicament comprises 10-20 parts of salvia miltiorrhiza bunge, 10-20 parts of angelica sinensis, 10-20 parts of yerbadetajo herba ecliptae, 10-20 parts of rhizoma drynariae, 10-20 parts of scutellaria baicalensis, 10-20 parts of astragalus mongholicus, 10-20 parts of peony bark, 10-20 parts of patrinia, 10-20 parts of suberect spatholobus stem, 10-20 parts of safflower, 10-20 parts of szechuan lovage rhizome, 10-20 parts of fructus kochiae, 10-20 parts of honeysuckle flower, 10-20 parts of fructus psoraleae and 1-10 parts of centipede. An external applied medicament comprises 10-30 parts of radix sophorae flavescentis, 10-30 parts of lithospermum, 10-30 parts of rhizoma smilacis glabrae, 10-30 parts of common cnidium fruit, 10-30 parts of rhizoma drynariae, 10-30 parts of amur corktree bark, 10-30 parts of cortex dictamni, 10-30 parts of sophora flower, 10-30 parts of oldenlandia diffusa, 1-10 parts of zaocys dhumnades, 1-10 parts of stellera chamaejasme and 10-30 parts of sulphur. The invention has the advantages of high pertinence, blood cooling and vigoration, blood stasis elimination, less toxic or side effect, short curing time and difficult recrudescency after curing and is convenient to use.

Description

Psoriatic Chinese medicine composition of a kind of treatment and preparation method thereof

Technical field

The present invention relates to contain medical preparation that derives from plant, animal or mineral component and preparation method thereof, psoriatic Chinese medicine composition of particularly a kind of treatment and preparation method thereof.

Background technology

Psoriasis is a kind of common dermatomycosis, belongs to frequently-occurring disease, also is psoriasis, for the cause of disease consistent definite saying is not also arranged at present.This disease is initially syringe needle or the big red pimple of the grain of rice, there is a small amount of white squama on the surface, pimple enlarges fusion gradually later on, become the few speckle of fingernail, coin or hand size, clear border, substrate is rubescent, can can become the sheet infringement of different shape by several piece to there not being several piece, the orlop squama is more firm, expose scarlet shiny surface after wiping off, often betide extremity, scalp, cervical region and trunk, many symmetries take place, and slight Pruritus is arranged, this refractory skin makes the patient taste varieties of misery, extremely decocts, torments.Psoriasis (psoriasis) is pimple, erythema squama, recurrent, chronic inflammatory disease dermatoses.This onset of disease is between twenty and fifty mostly, and is long-term difficult in case the majority of falling ill shows effect repeatedly.If Drug abuse, repeatedly repeatedly after, often obstinate difficult, severe patient is black and blue, burning itches accompanies each other and one day seems like a year.

Psoriasis is a commonly encountered diseases, frequently-occurring disease.China's sickness rate is 0.12%, and American-European sickness rate can reach 1-3%.Psoriatic treatment does not still have active drug at present, the progress of western medical treatment psoriasis innerlich anwenden object space face comprises cell toxicity medicament, retinoid medicine and immunosuppressant-regulator since the fifties, but curative effect all serious side reaction may take place than the powerhouse in these medicines.Another important therapeutic advance is light-chemotherapy, and it is evident in efficacy, but has potential carcinogenic danger.Can be divided into four types according to the observation of psoriasis outward appearance: homeliness type, erythrodermic, arthrosis type, pustule type.Clinical the most common with homeliness type, can be divided into for three phases, promptly carry out phase, resting stage, catagen.Clinical diagnosis characteristics performance: cover the silvery white squama of multilamellar on the erythema,, deviate from the shinny semi-transparent film of one deck pale red, mark thin film, sieve shape petechia is arranged with the squama blade coating.Pathological manifestations parakeratosis is diagnosis basis.The phase of carrying out, characteristics are that new skin lesion constantly occurs, and original skin lesion constantly enlarges, acute stage the skin lesion inflammation apparent in view, often show as cerise, be coated with above loose, come off easily silvery white squama, the periphery of skin lesion often have one the circle blush.Also claim stable phase resting stage, do not have newborn erythra, or less, and inflammation is not obvious, and blush alleviates, and the course of disease is long.

The psoriatic cause of disease is not clear fully as yet, and primary disease easily recurs, Gu need to repeat even long-term treatment.Psoriasis is again a kind of optimum dermatosis, not should be temporary transient alleviation in the treatment and emits the danger that serious side effects takes place.The immediate objective of curing psoriasis research is according to pathogenetic understanding, seeks curative effect and does not have serious side effects really, recurs less and medicine and therapy that remission time is long.The Chinese medicine action temperature and, have no side effect, be fit to prolonged application.The Chinese traditional treatment psoriasis has accumulated rich experiences for many years, should be put in order and study.The Scientific exploration detection means judges that the relation of herbal medicine efficacy and the different Chinese medicine rule of treatment and prescription and experiment drug effect is a break-through point of tcm development.Can further develop the psoriatic more effective prescription of clinical treatment based on this.

Be used for the treatment of the effective medicine for external use of refractory skin such as psoriasis at present, as PIYANPING, anthralin Ointment, chlorine fluorine Shu Shuan etc., generally all form by substrate and active ingredient modulation, select for use different substrate to can be formulated into different cream, frost (breast) dosage form, chemical substance is almost adopted in active ingredient entirely.The weak point of these existing common drugs mainly is: curative effect is all not ideal enough, easily recurrence after the drug withdrawal, and Western medicine, the side effect of chemicals life-time service are big.What have contains a large amount of hormones; In addition, also there is narrow application range in the medicine that has, and what have is only effective to certain several types in the psoriasis, not suitable to other type, not only invalid, increases the weight of on the contrary sometimes after the use; Though have effectively curative effect is slow, the course of treatment long, need just can manifest effect more than half a year to one year, these certainly will make patient economy burden overweight.The psoriatic Chinese medicine of present treatment has a variety of, but the ubiquity course of treatment long, take effect slow, toxic side effect, outbreak repeatedly, the characteristics that specific aim is not strong.Many patients are because inappropriate medication or mode, have had a strong impact on the confidence of patient to the primary disease treatment not to aggravating disease.Above therapeutic scheme all belongs to the refractory basis of taking stopgap measures, and easily recurrence causes bad mental pressure and serious financial burden to extensive patients, and allows the patient miss best occasion for the treatment.

Summary of the invention

Technical problem to be solved by this invention is: because problems of the prior art: be used for the treatment of the effective medicine for external use of refractory skin such as psoriasis, as PIYANPING, anthralin Ointment, chlorine fluorine Shu Shuan etc., generally all form by substrate and active ingredient modulation, select for use different substrate to can be formulated into different cream, frost (breast) dosage form, chemical substance is almost adopted in active ingredient entirely.Weak point is that mainly curative effect is all not ideal enough, easily recurrence after the drug withdrawal, and Western medicine, the side effect of chemicals life-time service are big, and what have contains a large amount of hormones; In addition, also there is narrow application range in the medicine that has, and what have is only effective to certain several types in the psoriasis, not suitable to other type, not only invalid, increases the weight of on the contrary sometimes after the use; Though have effectively curative effect is slow, the course of treatment long, need just can manifest effect more than half a year to one year, these certainly will make problems such as patient economy burden is overweight.Provide a kind of with strong points, the removing heat from blood and promoting blood circulation blood stasis dispelling, toxin expelling heat clearing away, and safety, toxic and side effects is little, and is easy to use, and healing time is short, cures the psoriatic Chinese medicine composition of treatment that the back is difficult for recurrence.

For solving the problems of the technologies described above, the invention provides the psoriatic Chinese medicine composition of a kind of treatment, form by endo-medicine and external used medicine, various raw materials in part by weight ratios are in the described endo-medicine: 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Herba Ecliptaes, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Radix Scutellariaes, 10～20 parts of the Radixs Astragali, 10～20 parts of Cortex Moutans, 10～20 parts of Herba Patriniae, 10～20 parts of Caulis Spatholobis, 10～20 parts on Flos Carthami, 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of the Fructus Kochiae, 10～20 parts of Flos Loniceraes, 10～20 parts of Fructus Psoraleaes, 1～10 part of Scolopendra; Various raw materials in part by weight ratios are in the external used medicine: 10～30 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Arnebiae (Radix Lithospermi)s, 10～30 parts of Rhizoma Smilacis Glabraes, 10～30 parts of Fructus Cnidiis, 10～30 parts of Rhizoma Drynariae, 10～30 parts of Cortex Phellodendris, 10～30 parts of Cortex Dictamnis, 10～30 parts in Flos Sophorae, 10～30 parts of Herba Hedyotidis Diffusaes, 1～10 part of Zaocys, 1～10 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～30 parts in sulfur.

The psoriatic Chinese medicine composition of described treatment, various raw materials in part by weight ratios are preferably in the endo-medicine: 10～15 parts of Radix Salviae Miltiorrhizaes, 10～15 parts of Radix Angelicae Sinensis, 10～15 parts of Herba Ecliptaes, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Radix Scutellariaes, 10～15 parts of the Radixs Astragali, 10～20 parts of Cortex Moutans, 10～20 parts of Herba Patriniae, 10～20 parts of Caulis Spatholobis, 10～20 parts on Flos Carthami, 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of the Fructus Kochiae, 10～20 parts of Flos Loniceraes, 10～20 parts of Fructus Psoraleaes, 1～5 part of Scolopendra; Various raw materials in part by weight ratios can be preferably in the external used medicine: 10～20 parts of Radix Sophorae Flavescentiss, 10～20 parts of Radix Arnebiae (Radix Lithospermi)s, 10～20 parts of Rhizoma Smilacis Glabraes, 10～20 parts of Fructus Cnidiis, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Cortex Phellodendris, 10～20 parts of Cortex Dictamnis, 10～20 parts in Flos Sophorae, 10～20 parts of Herba Hedyotidis Diffusaes, 1～5 part of Zaocys, 1～5 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～20 parts in sulfur.

The psoriatic Chinese medicine composition of described treatment, various raw materials in part by weight ratios can also be preferably in the endo-medicine: 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Herba Ecliptaes, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Radix Scutellariaes, 10～20 parts of the Radixs Astragali, 10～15 parts of Cortex Moutans, 10～15 parts of Herba Patriniae, 10～15 parts of Caulis Spatholobis, 10～15 parts on Flos Carthami, 10～15 parts of Rhizoma Chuanxiongs, 10～15 parts of the Fructus Kochiae, 10～15 parts of Flos Loniceraes, 10～15 parts of Fructus Psoraleaes, 1～8 part of Scolopendra; Various raw materials in part by weight ratios can also be preferably in the external used medicine: 10～25 parts of Radix Sophorae Flavescentiss, 10～25 parts of Radix Arnebiae (Radix Lithospermi)s, 10～25 parts of Rhizoma Smilacis Glabraes, 10～25 parts of Fructus Cnidiis, 10～25 parts of Rhizoma Drynariae, 10～25 parts of Cortex Phellodendris, 10～25 parts of Cortex Dictamnis, 10～25 parts in Flos Sophorae, 10～25 parts of Herba Hedyotidis Diffusaes, 1～7 part of Zaocys, 1～7 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～25 parts in sulfur.

The psoriatic Chinese medicine composition of described treatment, various raw materials in part by weight are than also being preferably in the endo-medicine: 15～20 parts of Radix Salviae Miltiorrhizaes, 15～20 parts of Radix Angelicae Sinensis, 15～20 parts of Herba Ecliptaes, 15～20 parts of Rhizoma Drynariae, 15～20 parts of Radix Scutellariaes, 15～20 parts of the Radixs Astragali, 15～20 parts of Cortex Moutans, 15～20 parts of Herba Patriniae, 15～20 parts of Caulis Spatholobis, 15～20 parts on Flos Carthami, 15～20 parts of Rhizoma Chuanxiongs, 15～20 parts of the Fructus Kochiae, 15～20 parts of Flos Loniceraes, 15～20 parts of Fructus Psoraleaes, 1～8 part of Scolopendra; Various raw materials in part by weight are than also being preferably in the external used medicine: 10～15 parts of Radix Sophorae Flavescentiss, 10～15 parts of Radix Arnebiae (Radix Lithospermi)s, 10～15 parts of Rhizoma Smilacis Glabraes, 10～15 parts of Fructus Cnidiis, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Cortex Phellodendris, 10～15 parts of Cortex Dictamnis, 10～15 parts in Flos Sophorae, 10～15 parts of Herba Hedyotidis Diffusaes, 1～6 part of Zaocys, 1～6 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～15 parts in sulfur.

For solving the problems of the technologies described above, the present invention also provides a kind of as has stated the preparation method of the psoriatic Chinese medicine composition of treatment, and the preparation method that its endo-medicine dosage form is a tablet may further comprise the steps:

Get the Scolopendra of described ratio of weight and number and use soak with ethanol, alcohol heating reflux extracts in the alcohol reflux jar, extracts three times; Filtrate merges, stand for standby use; All the other described components are mixed by proportioning, drop into pulverizer and be ground into fine powder, put into the acid and alkali-resistance infusion kettle after fine powder sieves, at normal temperatures and pressures, flooded 10～20 days with ethanol is common, reheat extracts, carry out squeeze and filter with medicinal residues, get filtrate after the separation, mixed with aforementioned extracting solution then; Be concentrated into relative density and be 1.06 concentrated solution, add starch and stir, after the tabletting oven dry tablet.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method that to treat psoriatic endo-medicine dosage form be capsule, may further comprise the steps:

A. Scolopendra being put into ethanol heat carries 3 times.

B. described all the other component medical materials heat in ethanol is carried 2 times.

C. extracted twice liquid is merged, reclaim ethanol, be concentrated into extractum;

D. with thick paste at hothouse in dry below 60 ℃, the medicine piece;

E. the medicine piece is ground into fine powder, crosses 120 mesh sieves, get the alcohol extraction fine powder; Incapsulate.

Among described step a and the step b, the raw medicinal material of getting described ratio of weight and number adds in 10 times of amount ethanol, can heating and refluxing extraction, each 1～2 hour, filtrate is merged, medicinal liquid; Extracting solution is left standstill.

Among the described step c, above-mentioned two kinds of extracting solution can be merged, will merge in the back 2 times extracting solution suction concentrating under reduced pressure jar, reclaim ethanol earlier, be decompressed to 0.03-0.08MPa again, temperature remains on 60-80 ℃, being concentrated into relative density is 1.20, the extractum that temperature to 60 is ℃-70 ℃.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method that to treat psoriatic external used medicine dosage form be liniment, may further comprise the steps:

Earlier the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) and Zaocys are put into the ethanol heating extraction three times, with the extracting solution usefulness of purchasing silently;

Again with described except that sulfur all the other components mix by proportioning, decoct with water 3 times, each 1-2 hour, decoction liquor is mixed;

After then said extracted liquid being mixed, add the sulfur that breaks into fine powder, the time spent directly is applied in the affected part.

The endo-medicine dosage form of the psoriatic Chinese medicine composition medicine of described treatment can be preferably: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, pill, powder, sublimed preparation, solution, injection, suppository, plaster, cream or drop; The external used medicine dosage form can be preferably: unguentum, spray, liniment, ointment or emplastrum.

Treat the using method of psoriatic external preparation, external preparation is embrocated the affected part, every day 3-5 time, embrocating 30 days continuously is a course of treatment.

Advantages such as compared with prior art teach, the present invention treats psoriatic Chinese medicine composition and has convenient drug administration, and medicament is easy to make, and is with low cost.The present invention adopts the Chinese crude drug of the different property of medicine, has carried out the science compatibility, can reach ideal therapeutic effect, and is with strong points, the removing heat from blood and promoting blood circulation blood stasis dispelling, toxin expelling heat clearing away, and safety, toxic and side effects is little, easy to use, healing time is short, cures the back and is difficult for recurrence, can create good social and be worth and economic interests.

The specific embodiment

Psoriasis is the dermatosis common disease, and motherland's medical literature has the record of similar disease, is called " psoriasis "." surgery great achievement " cloud: " Se Bai and itching has scratched Rhizoma Euonymus, is a kind of chronic and refractory dermatosis for psoriasis, skin such as rash scabies ".The psoriatic medicine of treatment is a lot of both at home and abroad at present, but curative effect is not ideal enough, and relapse rate is very high, and some medicine has serious adverse.Psoriasis claims psoriasis again, and its clinical manifestation is how hemorrhage with erythema, pimple, congestion, pruritus incrustation, chapped skin, pain, and comes off with a large amount of silvery whites or Lycoperdon polymorphum Vitt scurf.On the human health development history, psoriasis is having a strong impact on people's healthy and orthobiosis, and it is desquamation layer by layer, very itches unbearably erythema sheet sheet, outbreak repeatedly.Though psoriasis is threat to life not, but prolonged controlling do not sent out better in exposed position, as positions such as head, extremity, shirtfront, back, often make the normal person that the patient is produced detest, patient's body and mind is formed very big pressure, have a strong impact on life, work and social communication, 35% may hereditary offspring so that many patients feel depressed, agonizing.

This disease is easily examined refractory, and its cause of disease is very not clear and definite again, is the big difficult and complicated illness in the current department of dermatologry field.The doctor does not have the obvious and effective medicine to psoriatic treatment now.Existing on the market vitiligo medicine DeGrain, and easily repeatedly.

The present invention follows motherland's traditional theory, in conjunction with practice innovation development, mainly sets about from endogenous cause of ill, and selected medical material, science compatibility are made and a kind ofly can be promoted the Chinese medicine preparation that sufferer skin autoimmune improves by life-time service.Fructus Psoraleae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Arnebiae (Radix Lithospermi), Rhizoma Drynariae, Rhizoma Chuanxiong etc. have the rise of activation tyrosinase activity in the side, promote human body to improve immunity; Fructus Cnidii warming YANG collateral dredging; The Herba Ecliptae QI invigorating, the hemopoietic the lucid yang sending up; Liver and kidney tonifying, Chinese angelica blood supplementing nourishing the liver, Flos Carthami blood circulation promoting and blood stasis dispelling; Though the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Scolopendra are poisonous, can strengthen skin immunization power can use on a small quantity still; Flos Lonicerae, Cortex Moutan detoxicating speckle removing.

Herba Ecliptae is the herb of feverfew Eclipta prostrata, because when crumpling its stem and leaf, the juice of visible black color flows out, so cry " Herba Ecliptae " again, different name is Nanjing grass, Alternanthera sessilis (L.) DC. again.The sweet acid of nature and flavor, removing heat from blood, hemostasis, the kidney invigorating, tonifying YIN.Control haematemesis, hemoptysis, epistaxis, hematuria is had blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, leukorrhagia, pudendum pruritus due to damp pathogen.Herba Ecliptae frequency of utilization in the Chinese medicine beautifying ancient prescription is high, thinks crow palpus hair color, the key medicine of growth hair.Fry in shallow oil in Nanjing in " a thousand pieces of gold month "; Firm tooth crow moustache side, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) in " longevity parent endowment book " loose; The crow palpus teeth consolidating side of " the many wonderful recipes of health preserving "; Holy Benevolent Prescriptions control milphae side, all be to be principal agent with the Herba Ecliptae." Newly Revised Canon of Materia Medica " says that " juice is coated with and sends out eyebrow, gives birth to fast and numerous with Herba Ecliptae." Compendium of Material Medica says that its can " black moustache be sent out, kidney tonifying the moon." " book on Chinese herbal medicine justice " think that Herba Ecliptae " goes into the kidney nourishing YIN and the hair of growing." the short alcohol of Ming Dynasty well-known doctor Miao extremely praises highly Herba Ecliptae, says in " Bencao Jingshu ": " grass that bleaches at all times is when being victory now." Herba Ecliptae has the effect of activity of tyrosinase, improves immunity, the effect that sterilization relieves internal heat.。

Radix Angelicae Sinensis, its sweet in the mouth and weighing, so specially can enrich blood, its gas is light and hot, thus again can promoting the circulation of blood, invigorating middle warmer has, in the row benefit is arranged, the gas medicine in the sincere blood, the also panacea in the blood.About mending of assistant to mend then, thus can support nutrition blood, the QI invigorating spermatogenesis, settling five organs, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack then, so the relieving constipation bitterly of dispelling, relieving rigidity of muscles and joints is controlled contracture, paralysis, card such as dry, puckery.Nutrient QI being deficient and exterior syndrome being not relieved person, assistant is with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can loose greatly, and show not hold back the person, and help with Radix Et Rhizoma Rhei and so on, again can consolidating superficial resistance.Precisely because gas Xin Erdong, so desire its quiet person when keeping away it, the sliding benefaction of property is defecated and is not consolidated the person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.

The Rhizoma Chuanxiong suffering, temperature.Return liver, gallbladder, pericardium channel.The function blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for menoxenia, amenorrhea dysmenorrhea, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Rhizoma Chuanxiong is warm in nature, and the energy promoting blood circulation to remove blood stasis is the good medicine that nourishes blood.

Fructus Psoraleae is returned kidney; The heart; Spleen; Stomach; Lung meridian.Show that according to the study Fructus Psoraleae stimulates keratinocyte to discharge inflammatory mediator, act on the melanophore somatomedin, make remaining melanocyte propagation in epidermis or the hair follicle; The Fructus Psoraleae acrid in the mouth; Bitter in the mouth; Warm in nature returning through kidney; Pericardium; Spleen; Stomach; The lung meridian function cures mainly: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.Main insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; The sexual impotence essence; Frequent micturition; The enuresis; Failure of the kidney in receiving QI; Dyspnea due to deficiency is more than; Asthenia of both the spleen and kidney; The stool chronic diarrhea." Bencao Jingshu ": Fructus Psoraleae, energy warming the kidney; Give birth to sun in the moon, the key medicine of excessive fire benefit soil also.Its main five kinds of strain and seven kinds of impairment, the disease of lid edge impairment caused by overstrain, a lot of in asthenia of both the spleen and kidney, with its can warming the kidney, mend fire with the immature soil, being so incensed that to mend of kidney-Yang and rising in the kidney then then can digesting food, steam waste matter and change precise and tiny.Belong to lung on the spleen-QI transporting the essence to the whole body, support the five internal organs with honor, so the labor of main the five internal organs.Seven emotions hinder disease of viscera connecting with this channel.Wind cold caused by deficiency person, because of yang-energy is decayed, and the then air-cooled visitor that takes advantage of a weak point in opponent's defence so that bone marrow hinders and loses, the cold smart stream of kidney, and kidney governing bones store essential substances, marrow be smart this, the gas of kidney-Yang is solid, promptly before card see, solid itself and yang-energy is living, then preceding card removes in vain.The man is based on essence, and the married woman is based on blood, married woman vim and vigour person, and also still man's sun kidney that declines is cold and be the disease of blood prostration QI collapse caused by exhaustion of QI of the spleen and kidney, with the cold smart stream of man's kidney also.

The Rhizoma Drynariae hardship, temperature.Return kidney, Liver Channel.Function the kidney invigorating bone strengthening continues and hinders pain relieving.Be used for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, and the muscles and bones folding is hindered; The external treatment alopecia areata, vitiligo." Japan hanako materia medica " carries it: control malignant boil, the mashed meat of erosion, parasite killing.

Flos Carthami is warm in nature, acrid in the mouth.Function cures mainly and is applied to invigorate blood circulation latus rectum, eliminating stasis to stop pain.Be used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury." book on Chinese herbal medicine converges and says ": Flos Carthami, the medicine of removing blood stasis, promoting the circulation of blood and blood, accent blood also.Main tire produces all kinds of diseases and ailments and is trouble because of blood, or the tired bruise of blood, and coma in silence; Or lochia is robbed the heart, the umbilicus angina abdominis; Or the drop slurry is difficult living; Or afterbirth do not fall, and dead fetus in the uterus is all just before giving birth all cards, and non-Flos Carthami can not be controlled.If puerperal blood faints, locked mouth refer to hold in the hand; Or heresy goes into the blood chamber, and delirium is gone mad; Or blood expands in vexed, and the sudden syncope with rigidity is as extremely, be all puerperal all cards, non-Flos Carthami can not be decided.All friendship as the obstructed and cold and heat of amenorrhea done, or expired stomachache and purple black dripping, or injury from falling down and the QI and blood stasis of blood is long-pending, or skin infection sufferings and swollenly burst uneasyly, is cards of disharmony between QI and blood all, and non-Flos Carthami can not be transferred.

Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) suffering, hardship, flat.Poisonous.Eliminating stagnation is relieved oedema or abdominal distension through diuresis or purgation, pain relieving, parasite killing.Be used for aqueous vapor swelling, tuberculous lymphadenitis; Scabies, tinea are controlled in external, kill fly, maggot "." herbal classic " carries it: main cough with dyspnea, removing mass is poly-, diet, cold and heat, aqueous vapor, malignant boil, the erosion of scrofula cellulitis, diseases due to noxious agents produced by various parasites.The a small amount of external of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) plays sterilization, the effect of chafe regeneration capacity.

The Flos Lonicerae heat clearing away is loose malicious, and Compendium of Material Medica is carried " Flos Lonicerae is good at removing toxic substances, so control carbuncle, toxic swelling, skin ulcer tinea ... ".Since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the heating of treatment epidemic febrile disease, toxic-heat and blood stasis, diseases such as carbuncle and ulcer.Modern pharmacological research shows, that Flos Lonicerae has is antibacterial, antiviral, antiinflammatory, analgesic, regulate the effect traditional Chinese medical science such as immunity and think, Flos Lonicerae is cold in nature, sweet in the mouth, gas are put down, and has the effect of heat-clearing and toxic substances removing, can treat diseases such as pyretic toxicity abscess, carbuncle furuncle.And have the diffusing effect of a surname concurrently.The Flos Lonicerae antipyretic and antidote functions is quite strong, is product commonly used in surgery.

The Radix Salviae Miltiorrhizae hardship is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.Be used for the costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, the tumbling down pain of injury, menoxenia, the amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect.. " detailed outline " carries: Radix Salviae Miltiorrhizae, by " the sensible opinion of married woman " cloud, SIWU TANG is controlled the gynecopathy, pays no attention to antenatal puerperal, through water what, all can be general, only flavor Radix Salviae Miltiorrhizae looses, and cures mainly identical with it.The lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, peaceful tire, and the stillborn fetus that falls ends the metrorrhagia dysentery, the regulating menstruation arteries and veins.

Fructus Cnidii suffering, hardship, temperature; Slightly poisonous.Return kidney channel.Cure mainly warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; The external treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis is gynecological external use good medicine." Bencao Jingshu " carries: Fructus Cnidii, and bitter in the mouth is flat; " not Lu " be hot sweet nontoxic; Modern detailed its abnormal smells from the patient, when the warm-dryness syndrome of must holding concurrently, sun also.So swell and ache in housewife people's the moon, man's impotence pruritus due to damp pathogen removes stagnated QI, sharp joint, malignant boil." not Lu " warming the middle warmer and descending qi makes married woman's Zifu heat, and the man is cloudy strong, has made us son.Lid can dehumidify with tongue, temperature energy cold expelling, and suffering can be moistened kidney, and sweet energy strengthening the spleen is so can remove the wet disease of viscera connecting with this channel of all deficiency and coldness of married woman man.Cold-damp was both removed, and then disease is gone, performance Yiyang, thus disease, and have tonification also.

Radix Arnebiae (Radix Lithospermi) is cold in nature, sweet in the mouth, one-tenth.GUIXIN, Liver Channel.Function cures mainly removing heat from blood, invigorates blood circulation the detoxifcation rash.Be used for that heat in blood poison is contained, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood is used for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.

Scolopendra becomes, suffering, temperature.Poisonous.Return liver, spleen, lung meridian suffering, temperature; Poisonous.Return Liver Channel.Function cures mainly, endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.The toxicity of Scolopendra is to the skin malignant boil, and dermatitis has the effect of drawing out pus by applying a plaster to the affected part preferably.

Caulis Spatholobi property hardship, sweet, temperature.Return liver, kidney channel, enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation, supplementary Amplifications of the Compendium of Materia Medica carry it can cure numb hand and foot; Quadriplegia; Rheumatic arthralgia; The women has through uncomfortable; Dysmenorrhea.Be the good medicine of invigorating blood circulation.

Zaocys dispels the wind, collateral dredging, relieving convulsion.Be used for rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.Naja, Agkistrodon halys have been poisonous snake, and wind-damp dispelling, the meridian dredging effect are stronger, Zaocys and the two same usefulness, and it knowingly follows the example of a wrongdoer good.Be used for rheumatic arthralgia or rheumatoid arthritis, poker back etc.1 of Zaocys, soup is boiled in section.Add leaf fat, salt, a little seasoning of Rhizoma Zingiberis Recens, drink soup is eaten meat.Zaocys has expelling wind and removing dampness and Detoxication, for urticaria, eczema abscess certain prevention or therapeutic effect is arranged also.

Sulfacid, temperature; Poisonous.The external use anti pruritic parasite killing is treated skin ulcer; The fiery supporing yang relieving constipation of benefit for oral administration; External treatment is used for scabies, tinea alba, carbuncle of yin nature malignant boil; Take orally and be used for the sexual impotence cold foot, dyspnea due to deficiency cold asthma, deficiency and coldness constipation.Go into the diffusing clothes of ball after for oral administration the process of preparing Chinese medicine; Outer clothes are ground oil into powder and are transferred the coating affected part.

The Flos Sophorae traditional Chinese medical science is thought its bitter in the mouth, cold nature, returns liver, large intestine channel; Go into blood and hold back and fall, body slightly looses; Has cooling blood for hemostasis, the effect of purging liver-fire; Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia is spitted blood, epistaxis, liver-fire headache, conjunctival congestion and swelling pain, sore throat, aphonia, ulcer sores.And from the angle of doctor trained in Western medicine, it (is rutin, Rytub), material such as Quercetin (Quercetin), tannin, sophoradiol (sophoradiol), vitamin A (specifically can referring to the following scale that contains) that Flos Sophorae contains rutin.Rutin can be improved the function of blood capillary, keeps the normal resistance of blood capillary, prevent because of capillary fragility excessive, hemorrhage, the hypertension that permeability is too high to be caused, diabetes, can preventing of clothes is hemorrhage.

The Herba Patriniae nature and flavor are bitter flat, have the effect of heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs.Can cure acute appendicitis, dysentery, leucorrhea with red and white discharge, the stagnant stomachache of the stasis of blood in puerperal, conjunctival congestion and swelling pain.Go into stomach, large intestine, Liver Channel.Cure mainly heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.Be used for acute appendicitis, lung abscess and sore and toxic, the breast abdomen pain due to the excess-heat stasis of blood stagnates, the stagnant stomachache of the stasis of blood in puerperal waits disease.

The Radix Astragali is based on tonify deficiency, can invigorating QI to consolidate the body surface resistance, and diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Be used for that insufficiency of vital energy and blood, skin infection cave in, difficulty in discharging of pus or burst for a long time and do not hold back the person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration strengthening, i.e. the abscess suppuration granulation promoting of disunion for a long time.Modern medicine study shows that the Radix Astragali includes and multiple antibiotic effective ingredient, and the energy enhancing body's immunological function, therefore can also be used to prevent the generation of some infectious disease." book on Chinese herbal medicine meets former " carries: " Radix Astragali can all void of tonifying five ZANG-organs, controls the stringy pulse spontaneous perspiration, rushes down YIN-fire, removes lung-heat, losslessly then sends out, and has antiperspirant then to end." be the good medicine of promoting resistance and defence disease.

Herba Hedyotidis Diffusae is Herba Hedyotidis Diffusae, two leaves, Herba Commelinae Bengalensis, Chinese Lobelia again.Mildly bitter flavor, sweet, cold.Go into stomach, large intestine, small intestine meridian, the clearing up internal heat by using drugs of bitter in taste and cold in nature detoxifcation, sweet cold eliminating damp-heat has stronger removing toxicity for eliminating carbuncles effect to carbuncle, pharyngalgia, snakebite etc.Generally be used for the treatment of sore, laryngopharynx swelling and pain, abdominalgia with intestinal abscess, venom, also be used for the puckery pain of pyretic stranguria, dysuria.Be the good medicine of damp eliminating of drawing out pus by applying a plaster to the affected part.

The Radix Sophorae Flavescentis hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel heat clearing and damp drying, parasite killing, diuresis.Be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, dermatomycosis, eczema, skin pruritus, scabies leprosy; Often being used in combination with Hedyotidis Diffusae, is the external good medicine of treatment dermatomycosis.

Cortex Dictamni is cold in nature, bitter in the mouth.Cure mainly heat clearing and damp drying, the detoxifcation of dispeling the wind.Be used for that damp and hot sore, yellow fluid are dripping, dermatomycosis, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine.The normal medicines such as Radix Sophorae Flavescentis, the Fructus Kochiae that cooperate are with using." book on Chinese herbal medicine is original " carries it: " control all mange, aversion to wind, scabies, Fructus Myricae rubrae, all skin ulcer pyretic toxicity.″

Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The Cortex Phellodendri nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency." Chinese pharmacopoeia is carried the power of Cortex Phellodendri heat clearing and damp drying, and is similar to Radix Scutellariae, Rhizoma Coptidis, but is good to remove the damp and hot of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.

Rhizoma Smilacis Glabrae is sweet, light, and is flat.GUIXIN, lung, spleen, kidney channel.The function promoting diuresis to eliminate damp pathogen, the spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful." herbal classic " carries it: " the contrary gas of the main breast side of body, melancholy is angerd frightened heresy and is probably throbbed with fear, and the heart is the knot pain down, cold and heat stuffy sensation with restlessness, cough with dyspnea, mouthful burnt dry tongue, diuresis." " not Lu ": " only quenches one's thirst, likes to sleep, and big abdomen drenches drop, the disease due to obstruction of QI of middle-JIAO expectorant water, and edema is drenched knot.Open the breast internal organs, transfer visceral-qi, cut down the kidney heresy, long cloudy, physical strength profiting is during guarantor god keeps." " property of medicine opinion ": " appetizing, preventing or arresting vomiting is contrary, kind tranquilizing mind.Main consumptive lung disease expectorant is stopped up.Control pediatric epilepsy scared, trusted subordinate's distension, married woman's pyretic stranguria.″

The Fructus Kochiae is cold in nature, acrid in the mouth, hardship.The energy clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.Be used for diseases such as difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus." key medicine is divided agent " carries: " go into kidney, bladder two warps.Diuresis, clearing away damp-heat.Control dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.

Radix Scutellariae has heat clearing and damp drying, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibiotic not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are by the strong characteristics of broad-spectrum antibacterial action, and it is special severe to be used in the fungal culture microbial contamination, and are fine with Radix Scutellariae extracting solution effect." Bencao Jingshu ": Radix Scutellariae, its property is respectful clearly, so remove evil: so bitter in the mouth dampness; So YIN-cold wins heat, so main all heat.All hot persons, pathogenic heat with all over heat also, jaundice, intestinal be out-of-the-way, let out dysentery, the disease of all damp and hot victory is also analysed it, then all diseases are from recover.Bitter cold can be removed damp and hot, thus small intestinal profit and water from pursuing, the source is clearly then flowed also clean.The blood person of closing, excess-heat is at blood system, instant heating human blood chamber, it is obstructed to make us amenorrhea, damp and hot separating, then Ying Qi is clearly and voluntarily also.Malignant boil cellulitis erosion person, heat in blood is then stayed knot, and is that carbuncle stain is mashed also: the acute scleritis person, the fire of moxibustion blood trouble also, the removing heat from blood heat extraction, then spontaneous recovery also.

The Cortex Moutan clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.Kind energy clearing heat in YING system branch, blood system excess-heat, the hemostasis of function clearing away heat and cooling blood.Control epidemic febrile disease heat and go into nutrient blood, send out speckle, haematemesis, epistaxis due to the absurd row of forcing blood, but water distribution Cornu Bovis seu Bubali, Radix Rehmanniae, Radix Paeoniae Rubra etc. are medicinal; Control maculae caused by violent heat pathogen, it is medicinal to join Fructus Gardeniae, Radix Et Rhizoma Rhei, Radix Scutellariae etc.

It is that the sweet preparation method of refining pill of agent comprises that the present invention treats psoriatic oral medicine: get Radix Salviae Miltiorrhizae 1000g, Radix Angelicae Sinensis 1000g, Herba Ecliptae 1000g, Rhizoma Drynariae 1000g, Radix Scutellariae 1000g, Radix Astragali 1000g, Cortex Moutan 1000g, Herba Patriniae 1000g, Caulis Spatholobi 1000g, Flos Carthami 1000g, Rhizoma Chuanxiong 1000g, Fructus Kochiae 1000g, Flos Lonicerae 1000g, Fructus Psoraleae 1000g, Scolopendra 100g; The raw medicinal material of getting above-mentioned ratio of weight and number soaked 1 hour, placed multi-function extractor then, decocted amount of water for the first time and be 10 times of medical material, decoct, when being heated to 100 ℃, pick up counting, after little the boiling 2 hours, emit medicinal liquid, put in the fluid reservoir from the feed opening filtration; Decoct for the second time, amount of water is 10 times of amounts of medical material, is heated to 100 ℃, after little the boiling 2 hours, extracts medicinal liquid out, merges with the medicinal liquid that decocts for the first time; With merging in the back 2 times decoction liquor suction concentrating under reduced pressure jar, be decompressed to 0.03-0.08MPa, temperature remains on 75 ℃, and being concentrated into relative density is 1.20, the extractum of temperature to 65 ℃; Put into baking oven, be controlled at 75 ℃, dry postcooling, mixing with Mel is twisted into slice, the wax seal packing.

The preparation method of capsule comprises: Scolopendra 100g is put into ethanol heat carry 3 times; With described all the other component medical material Radix Salviae Miltiorrhizae 1000g, Radix Angelicae Sinensis 1000g, Herba Ecliptae 1000g, Rhizoma Drynariae 1000g, Radix Scutellariae 1000g, Radix Astragali 1000g, Cortex Moutan 1000g, Herba Patriniae 1000g, Caulis Spatholobi 1000g, Flos Carthami 1000g, Rhizoma Chuanxiong 1000g, Fructus Kochiae 1000g, Flos Lonicerae 1000g, Fructus Psoraleae 1000g, heat is carried 2 times in ethanol.Add in 10 times of amount ethanol, heating and refluxing extraction, each 1～2 hour, filtrate is merged, get medicinal liquid; Extracting solution is left standstill, above-mentioned two kinds of extracting solution are merged, will merge in the back 2 times extracting solution suction concentrating under reduced pressure jar, reclaim ethanol earlier, be decompressed to 0.03-0.08MPa again, temperature remains on 60-80 ℃, being concentrated into relative density is 1.20, the extractum that temperature to 60 is ℃-70 ℃.With thick paste at hothouse in dry below 60 ℃, the medicine piece; The medicine piece is ground into fine powder, crosses 120 mesh sieves, get the alcohol extraction fine powder; Incapsulate.

The preparation method of external-use tincture comprises:

Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 150g and Zaocys 300g are immersed 95% soak with ethanol three times, and each soak time was respectively 2 hours, 1 hour, 1 hour; Each 80～85 ℃ of heat in back of soaking are extracted, and alleviate toxicity; The ratio of weight and number of the used ethanol and the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) and Zaocys is respectively: for the first time 10 times of amounts, the second time 6 times of amounts, 6 times of amounts for the third time; Merge three times ethanol extract, be concentrated into relative density and be 1.06 concentrated solution, stand for standby use; With Radix Sophorae Flavescentis 3000g, Radix Arnebiae (Radix Lithospermi) 3000g, Rhizoma Smilacis Glabrae 3000g, Fructus Cnidii 3000g, Cortex Phellodendri 3000g, Cortex Dictamni 3000g, Flos Sophorae 3000g, Herba Hedyotidis Diffusae 3000g, sulfur 3000g, described component is mixed by proportioning, drop into pulverizer and be ground into fine powder, put into the acid and alkali-resistance infusion kettle after fine powder sieves, at normal temperatures and pressures, flooded 10～20 days with ethanol is common, liquid and medicinal residues that dipping is good carry out squeeze and filter, get filtrate after the separation, mixed with aforementioned concentrated solution then.External-use tincture, but smear the affected part every day three times.

The preparation method of externally applied liniment comprises:

Get Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80g, Zaocys 100g adds heating extraction three times in 10 times of amount ethanol, each 1 hour, the extracting solution stand for standby use, again with Radix Sophorae Flavescentis 2000g, Radix Arnebiae (Radix Lithospermi) 2000g, Rhizoma Smilacis Glabrae 2000g, Fructus Cnidii 2000g, Rhizoma Drynariae 2000g, Cortex Phellodendri 2000g, Cortex Dictamni 200g, Flos Sophorae 2000g, Herba Hedyotidis Diffusae 2000g adds 10 times of water gagings and decocts each one hour three times, after then said extracted liquid being mixed, add the sulfur 2000g that breaks into fine powder, the time spent directly is applied in the affected part.

The preparation of oral capsule may further comprise the steps: earlier Scolopendra 100g is put into ethanol heat and carry 3 times.Heating and refluxing extraction, each 1～2 hour, filtrate is merged, get medicinal liquid; Extracting solution is left standstill.Again with described all the other component medical material Radix Salviae Miltiorrhizae 1000g, Radix Angelicae Sinensis 1000g, Herba Ecliptae 1000g, Rhizoma Drynariae 1000g, Radix Scutellariae 1000g, Radix Astragali 1000g, Cortex Moutan 1000g, Herba Patriniae 1000g, Caulis Spatholobi 1000g, Flos Carthami 1000g, Rhizoma Chuanxiong 1000g, Fructus Kochiae 1000g, Flos Lonicerae 1000g, Fructus Psoraleae 1000g, heat is carried 2 times in ethanol.Heating and refluxing extraction, each 1～2 hour, filtrate is merged, get medicinal liquid; Extracting solution is left standstill; Above-mentioned two kinds of extracting solution are merged, will merge in the back 2 times extracting solution suction concentrating under reduced pressure jar, reclaim ethanol earlier, be decompressed to 0.03-0.08MPa again, temperature remains on 60-80 ℃, and being concentrated into relative density is 1.20, the extractum that temperature to 60 is ℃-70 ℃; With thick paste at hothouse in dry below 60 ℃, the medicine piece; The medicine piece is ground into fine powder, crosses 120 mesh sieves, promptly get capsule in incapsulating.

The preparation method that unguentum is smeared in external may further comprise the steps:

Get Zaocys 300g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 150g, Radix Sophorae Flavescentis 3000g, Radix Arnebiae (Radix Lithospermi) 3000g, Rhizoma Smilacis Glabrae 3000g, Fructus Cnidii 3000g, Cortex Phellodendri 3000g, Cortex Dictamni 3000g, Flos Sophorae 3000g, Herba Hedyotidis Diffusae 3000g, sulfur 3000g, described component is mixed by proportioning, drop into pulverizer and be ground into fine powder, put into the acid and alkali-resistance infusion kettle after fine powder sieves, at normal temperatures, flooded 20 days with ethanol is common, liquid and medicinal residues that dipping is good carry out squeeze and filter, get filtrate after the separation, the filtrate heating is concentrated into pasty state, put into the oven for drying postcooling, grind to form fine powder, add vaseline and reconcile into pasty state.Can directly smear the affected part.

Pharmacology's toxicity test

1. skin irritation test

Get rabbit and shave hair, induce and excite contact test with external used medicine tincture of the present invention, viewing test rabbit after 24 hours and 48 hours, all loseing skin has phenomenons such as erythema and edema, with the negative control group zero difference.The result shows that this tincture is bordering on zero to dermoreaction intensity, does not promptly have skin allergic reaction, and clinical practice is safe and reliable.Acute skin irritation test: these product are according to 6.3 joints in Ministry of Public Health " cosmetics health standard " (2002) second portions " skin irritation/corrosion test ", male 4 of Japan large ear rabbit, body weight 2kg～3kg, getting these product 0.5g directly spreads upon on the skin of animal left side (opposite side in contrast), adopt blocking test, 4 hours application time, after the off-test with the residual thing that tried of warm water washing, in remove tried thing after 1h, 24h, 48h and 72h observe animal respectively and are tried to distinguish dermoreaction with the check plot, the top average is " 0 ", judges that these product are to the animal skin nonirritant.

2. long term toxicity test

Select the SD rat for use, give variable concentrations (18.0,6.0, the Chinese medicine composition tablet of the present invention of 2.0g crude drug/kg), irritate stomach every day once, continuous 90 days, respectively organized 1/2 animal (male and female half and half) extremely that lives in 24 hours after the last administration, all the other 1/2 animals continuation observation, 2 all backs are extremely alive.Duration of test is observed outward appearance, general behavior, food ration, the body weight change of animal, after the administration 90 days and carry out hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) in 2 weeks of drug withdrawal and index inspections such as blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology.Result of the test shows: Chinese medicine composition of the present invention is good at high, medium and low dosage treated animal general state, all no abnormal variation of outward appearance sign, behavioral activity, food-intake and body weight gain; Three dosage groups and matched group hematological examination, blood biochemical are learned, the urine biochemical analysis is all in normal range, do not have significant difference between group; Each is organized the main organs histopathological examination and shows no obvious abnormalities.The These parameters drug withdrawal is not seen change after 2 weeks yet.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test Chinese medicine composition of the present invention high, medium and low three dosage (18.0,6.0, the 2.0g crude drug/kg) administration in continuous 90 days does not have obvious influence to rat, no clear and definite toxicity target organ and sensitive indicator, the retardance toxic reaction is not seen in the convalescent period observation yet, points out the dosage safety of Chinese medicine composition clinical practice of the present invention higher.

Pharmacodynamic experiment

1. proinflammatory agent is brought out the influence of mice ear inflammation

Get 40 of mices, be divided into four groups at random, each Mus ig administration, once a day, continuous three days; The high low dosage group of preparation of the present invention is respectively: 7.8g/kg (0.3ml/20g), 3.9g/kg (0.3ml/20g), Etretinate electuary group is 12g/kg, matched group is with the isometric(al) normal saline, 1h after the last administration, 0.1ml is applied to two of mouse right ears with proinflammatory agent (dimethylbenzene), left side ear compares, behind the 4h with the garden shape rustless steel punching pin of diameter 9mm with about two auricles sweep away, weigh respectively, with left and right sides ear weight difference as swelling degree index, table 1 is the result show, the high and low dose group of preparation of the present invention has the obvious suppression effect to mice ear inflammation.

The influence of table 1 pair mouse ear inflammation (x ± SD)

Compare with matched group: * P＜0.05

Experimental example 2: Dichlorodiphenyl Acetate causes the influence of white mice writhing response

Get 40 of mices, grouping, route of administration, time and dosage are the same, 1h after the last administration, the acetic acid normal saline 0.1ml/10g body weight of ip1%, what observed and recorded was respectively organized mice in 30 minutes turns round the body number of times, and table 2 is the result show, this medicine reduces the body number of times explanation preparation of the present invention of turning round that acetic acid causes significantly significant analgesia role.

The influence of table 2 Dichlorodiphenyl Acetate induced mice writhing response (x ± SD)

Compare with matched group: * * P＜0.01

Experimental example 3: itching-relieving action

40 of Cavia porcelluss, be divided into 4 groups at random, 4 of matched groups, each 5 of three administration groups, the equal ig administration of each Mus, matched group gives the isometric(al) normal saline, continuous 5 days, the experiment proxima luce (prox. luc), hair is shaved on the right back instep of each Mus, test the same day, abrade right back instep with coarse sandpaper and shave hair place (area 1cm 2.), 30min after the last administration, beginning is only dripped 0.01% 0.05ml/ of histamine phosphate at the wound surface place, the back complies with 0.01% every 3min, 0.02%, 0.03%, 0.04% progressive concentration, only be 0.05ml/ at every turn, directly cause and Cavia porcellus occurs and later lick right back foot, later to lick the right back histamine phosphate's total amount that is given when sufficient be itch-threshold to occur Cavia porcellus at last, record and itch-threshold of each group relatively: as seen from Table 3, preparation of the present invention has the effect that improves the Cavia porcellus itch-threshold, and antipruritic effect is obvious.

Table 3 itching-relieving action result

Compare with matched group: * * P＜0.01

Experimental example 4: to Immune Effects

Influence to Turnover of Mouse Peritoneal Macrophages (M φ) phagocytic function: experiment grouping, route of administration, dosage is with 1.1, once a day, continuous five days, 2h after the last administration, each only organizes equal lumbar injection 5% chicken red blood cell of mice (CRBC) suspension 0.5ml/, puts to death animal behind the 12h, cuts off abdominal cavity skin, intraperitoneal injection of saline water 2ml: the pavilion flicking is rubbed abdominal part, get peritoneal fluid after 2 minutes and be tiled on the microscope slide, hatch 30min for 37 ℃, wash away free cell and dry up, fix with 1: 1 acetone-methanol solution, Gicmsa-wright dyeing is done the oily mirror in back and is checked counting down, calculates percentage rate and phagocytic index that 200 abdominal cavity M φ engulf CRBC, the result shows from table 4, and this medicine high dose group can significantly improve the phagocytic function of mouse peritoneal M φ.

The influence of table 4 pair Turnover of Mouse Peritoneal Macrophages phagocytic function (x ± SD)

Compare with the contrast level: * P＜0.05 * * P＜0.01

Experimental example 5: antibacterial action

Get 40 of mices, be divided into 4 groups at random, can make staphylococcus and 0.5ml/ infecting mouse of streptococcus bacterium liquid lumbar injection of 90% dead mouse during with trial test, each bacterium liquid is selected two groups of mices, and (wherein one group is control animal, one group is the administration animal), infect each Mus of back and isolate nursing, the administration group is 12 hours ig administration 7.8g/kg before and after infection bacteria species respectively, secondary is given 15.6g/kg altogether, matched group gives the equivalent normal saline, observe mortality rate in the mice 48 hours: the results are shown in Table 5, from table, can find out that preparation of the present invention has bacterial-infection resisting effect preferably.

The influence of bacterial infection in the table 5 pair animal body

Compare with matched group: * P＜0.05 * * P＜0.01

The clinical experiment explanation

1. physical data: I accept psoriasis vulgaris 84 examples for medical treatment by institute's in October, 2006 to 2009 year December, am divided into two groups at random.40 examples are organized in treatment, wherein male 24 examples, women 16 examples; 18～68 years old age, average 39.5 ± 11.3 years old; The course of disease 1～170 month, average 90.5 ± 40.2 months.Matched group 44 examples, wherein male 26 examples, women 18 examples; 19～65 years old age, average 41 ± 10.5 years old; The course of disease 1～181 month, average 88 ± 42 months.More than two groups of data analyze difference through Ridit there are no significant (P＞0.05), have comparability.

2. case inclusion criteria

The diagnostic criteria of psoriasis vulgaris: first time-out is red pimple of pinhead-sized pale red of medicated cap or squama or maculopapule, and boundary is clear, and the surface is covered with the silvery white squama of exsiccant multilamellar, is the Muscovitum shape, winds on every side with blush, and substrate is soaked into obviously.Skin lesion enlarges or is fused into the speckle shape, and squama thickens, and exposes the shinny semi-transparent film of one deck pale red after striking off, i.e. the thin film phenomenon.Strike off thin film and see the petechial hemorrhage phenomenon.Skin lesion is sent out in scalp, extremity well and is stretched side, also can general in whole body everywhere.Get rid of age of sucking, gravid woman, immunologic hypofunction person, skin lesion area less than body surface area more than 20% and the specific type person.Do not carry out any treatment in two weeks.

3. Therapeutic Method

The treatment group is applied to the affected part with Chinese medicine for external application of the present invention, and every day 2 times, matched group is applied to the affected part with tretinoin emulsifiable paste (0.025% tretinoin cream, Chongqing China nation pharmaceutical manufacturing), and every day 2 times, two groups of 2 weeks of medication were 1 course of treatment, observe the curative effect after 1 course of treatment.

4. evaluation index

Adopt PASI (psoriasis area and severity in2dex) methods of marking.The thickness of plaque psoriasis, erythema, 3 indexs of squama are all kept the score by 0～4 common Pyatyi, and (0=does not have, 1=is slight, 2=moderate, 3=severe, 4=utmost point severe), the skin lesion area by 1～6 totally six grades keep the score, skin lesion area≤10% is 1 minute,＞10% is 2 minutes,＞30% is 3 minutes,＞50% is 4 minutes, and＞70% is 5 minutes, and＞90% is 6 minutes.PASI total points computing formula is: PASI total points=0.1 * head surface integration * women's head-ornaments severity branch+0.3 * trunk area branch * trunk severity branch+0.2 * upper limb area branch * upper limb severity branch+0.4 * lower limb area branch * severe lower extremity degree branch.

5. efficacy determination

Fill in the observation form by observational technique, except that ordinary circumstance, write down variation, curative effect of medication and the side effect of patient front and back symptom, sign especially.Curative effect judging standard: recovery from illness: pimple or speckle disappear, flatten, and do not have new breakout, no gargalesthesia.Psoriasis PASI scoring descends 〉=90%.Produce effects: pimple or speckle attenuation or part disappear, and gargalesthesia obviously alleviates.Psoriasis PASI scoring descends 60%～80%.Effectively: the attenuation to some extent of pimple or speckle, gargalesthesia alleviates to some extent.Psoriasis PASI scoring descends 30%～60%.Invalid: the skin lesion no change, psoriasis PASI scoring descends＜30%.

6. statistical method

The relatively employing chi-square criterion of enumeration data, with P＜0.05 for statistical significance is arranged.

The result

A. two groups of curative effects relatively

After treating for 2 weeks, two groups of none routine cured persons, two groups of curative effects compare, processing by statistics (OK * and the tabulation chi-square criterion), difference does not have significance (χ 2=2.125, P＞0.05).See Table 1.

Table 1 liang group curative effect comparison (example, %)

Group	The example number	Produce effects	Effectively	Invalid
					The treatment group	40	6(14.6％)	20(48.8％)	15(36.6％)
Matched group	44	6(13.6％)	22(50.0％)	16(36.4％)

Annotate: two groups are compared χ 2=2.125, P＞0.05

B. untoward reaction

Treatment has slight twinge after organizing 7 examples (accounting for 17.1%) medication, disappears after the drug withdrawal, after matched group 6 examples (13.6%) medication slight causalgia is arranged, and disappears after the drug withdrawal, and two groups of adverse reaction rates compare, χ 2=0.19, and P＞0.05, difference does not have significance.

Embodiment 1: Xu certain, woman, 54 years old, workman.December in 2008 first visit on the 17th.The main suit: suffered from psoriasis 26 years, diffusion increased the weight of nearly 20 years after 3 years, through his institute's training diagnosis and treatment, used Chinese medicine and western medicine treatment by oral administration of medicines externals such as bimolane, aminopterin, took a turn for the better when controlling, and drug withdrawal is recurred soon.Examine quarter: scalp is to the breast abdominal part, carries on the back to buttocks and extremity to be covered with the attached squama of patch shape erythema.This is a psoriasis vulgaris, and traditional Chinese medical science typing is a blood-heat type, oral medicinal herb prescription: Radix Salviae Miltiorrhizae 10g, Radix Angelicae Sinensis 15g, Herba Ecliptae 10g, Rhizoma Drynariae 15g, Radix Scutellariae 10g, Radix Astragali 10g, Cortex Moutan 15g, Herba Patriniae 10g, Caulis Spatholobi 15g, Flos Carthami 15g, Rhizoma Chuanxiong 15g, Fructus Kochiae 10g, Flos Lonicerae 15g, Fructus Psoraleae 10g, Scolopendra 5g; Various raw materials in part by weight ratios are in the external used medicine: Radix Sophorae Flavescentis 20g, Radix Arnebiae (Radix Lithospermi) 20g, Rhizoma Smilacis Glabrae 15g, Fructus Cnidii 15g, Rhizoma Drynariae 15g, Cortex Phellodendri 20g, Cortex Dictamni 20g, Flos Sophorae 15g, Herba Hedyotidis Diffusae 15g, Zaocys 10g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 1g, sulfur 15g.For oral administration being decocted in water for oral dose divided sooner or later and taken for 2 times.Externally applied liniment.Treat clinical cure after 5 months.Followed up a case by regular visits to 1 year, and do not see recurrence.

Embodiment 2: Lee, and the man, 45 years old, went to a doctor in August, 2008.The main suit: the erythema squama appears in finger-joint, carpal joint, elbow joint, after develop into head term portion.History of present illness: a few days ago after drinking, find that there is small size point-like erythema in finger-joint portion next day, white squama was found to each articulations digitorum manus of right-hand man afterwards, on carpal joint, the elbow joint, very itched unbearably, and dermatological department is diagnosed as psoriasis through city hospital.Go around various big hospital, consult all famous physicians one can find, used a large amount of Chinese medicine, Western medicine, do not have special curative effect.Use Chinese medicine preparation of the present invention, for oral administration: Radix Salviae Miltiorrhizae 15g, Radix Angelicae Sinensis 10g, Herba Ecliptae 15g, Rhizoma Drynariae 15g, Radix Scutellariae 10g, Radix Astragali 10g, Cortex Moutan 15g, Herba Patriniae 10g, Caulis Spatholobi 10g, Flos Carthami 15g, Rhizoma Chuanxiong 15g, Fructus Kochiae 10g, Flos Lonicerae 15g, Fructus Psoraleae 10g, Scolopendra 6g; Various raw materials in part by weight ratios are in the external used medicine: Radix Sophorae Flavescentis 20g, Radix Arnebiae (Radix Lithospermi) 20g, Rhizoma Smilacis Glabrae 15g, Fructus Cnidii 15g, Rhizoma Drynariae 15g, Cortex Phellodendri 20g, Cortex Dictamni 20g, Flos Sophorae 20g, Herba Hedyotidis Diffusae 20g, Zaocys 10g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2g, sulfur 15g.For oral administration being decocted in water for oral dose divided sooner or later and taken for 2 times.Externally applied liniment.Treat clinical cure after 2 months.Followed up a case by regular visits to 1 year, and do not see recurrence.

Embodiment 3: Feng, and the man, 33 years old, consultation time in February, 2006 throwing was examined.The main suit: there was the desquamation erythema on the whole body 3 years.History of present illness: the patient found trunk, the block erythema of head appearance point before January, was covering silver bits layer.Pruritus slightly successively goes that each hospital diagnosis is a psoriasis in Beijing, the Shanghai City, external treatment Chinese medicine for oral administration Western medicine, all the time be not interrupted treatment, once used washout, and be coated with and ooze medicament, though antipruritic temporarily, the cerise that skin lesion but becomes, begin with " PIYANPING " effectively, itch with skin does not recently act at all, through inquiring, the patient claims: diseases caused by exogenous pathogenic factor, throat pain, skin lesion showed increased whenever, eat pungent fish raw meat and the flushing speckle of back skin ulcer of drinking weighs, itches very, inspection, patient's purplish tongue point are red, yellow and greasy fur, pharynx cheek color are red; Auscultation and olfaction do not have special, palpation, stringy and rolling pulse; The dermatological department situation: trunk, brothers, head, see cerise class color rash be dispersed in distribution all that coin differs in size, the visible egg of back and duplex top class in a kindergarten piece is covered with silvery white squama on the skin, the sieve shape petechia positive.Use Chinese medicine preparation of the present invention, for oral administration: Radix Salviae Miltiorrhizae 15g, Radix Angelicae Sinensis 10g, Herba Ecliptae 10g, Rhizoma Drynariae 15g, Radix Scutellariae 10g, Radix Astragali 10g, Cortex Moutan 15g, Herba Patriniae 15g, Caulis Spatholobi 10g, Flos Carthami 15g, Rhizoma Chuanxiong 15g, Fructus Kochiae 10g, Flos Lonicerae 15g, Fructus Psoraleae 10g, Scolopendra 7g; Various raw materials in part by weight ratios are in the external used medicine: Radix Sophorae Flavescentis 25g, Radix Arnebiae (Radix Lithospermi) 25g, Rhizoma Smilacis Glabrae 15g, Fructus Cnidii 15g, Rhizoma Drynariae 15g, Cortex Phellodendri 20g, Cortex Dictamni 20g, Flos Sophorae 20g, Herba Hedyotidis Diffusae 20g, Zaocys 10g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2g, sulfur 25g.For oral administration being decocted in water for oral dose divided sooner or later and taken for 2 times.Externally applied liniment.Treat clinical cure after 5 months.Followed up a case by regular visits to 1 year, and do not see recurrence.

Embodiment 4: Ma, and the woman, 16 years old,, the agricultural machinery school student, in December, 2007 is gone to a doctor.History of present illness: over 5 years, extremity, trunk generation red rash, patch map shape, extremity portion finds skin lesion before 5 years.Once look for an old docter of TCM to take traditional Chinese medicine at this city and the state of an illness is alleviated, can be kept temporarily, idol has the arm place point-like erythra to occur, and 2006, the morbidity that once eats seafood was merged in flakes with the back especially, and whole back looks like pasting a Corii Caprae seu Ovis, and the imperception of touching is being covered the canescence squama.Pulse condition: deep and slow, picture of the tongue: yellow fur, matter are red.The doctor trained in Western medicine rash is disconnected: psoriasis carries out the phase.Chinese medical discrimination: blood-deficiency and wind-dry, blood deficiency are sent out and are white scar.Method of treatment: nourishing blood to expel wind, nourshing Yin and drynsessmoistening prescription.Radix Salviae Miltiorrhizae 15g, Radix Angelicae Sinensis 15g, Herba Ecliptae 10g, Rhizoma Drynariae 10g, Radix Scutellariae 10g, Radix Astragali 10g, Cortex Moutan 15g, Herba Patriniae 15g, Caulis Spatholobi 15g, Flos Carthami 15g, Rhizoma Chuanxiong 15g, Fructus Kochiae 15g, Flos Lonicerae 15g, Fructus Psoraleae 10g, Scolopendra 7g; Various raw materials in part by weight ratios are in the external used medicine: Radix Sophorae Flavescentis 25g, Radix Arnebiae (Radix Lithospermi) 25g, Rhizoma Smilacis Glabrae 15g, Fructus Cnidii 25g, Rhizoma Drynariae 15g, Cortex Phellodendri 25g, Cortex Dictamni 20g, Flos Sophorae 20g, Herba Hedyotidis Diffusae 20g, Zaocys 10g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 3g, sulfur 25g.For oral administration being decocted in water for oral dose divided sooner or later and taken for 2 times.External-use tincture.Treat clinical cure after 5 months.Followed up a case by regular visits to 1 year, and do not see recurrence.

Claims

1. treat psoriatic Chinese medicine composition for one kind, it is characterized in that, form by endo-medicine and external used medicine, various raw materials in part by weight ratios are in the described endo-medicine: 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Herba Ecliptaes, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Radix Scutellariaes, 10～20 parts of the Radixs Astragali, 10～20 parts of Cortex Moutans, 10～20 parts of Herba Patriniae, 10～20 parts of Caulis Spatholobis, 10～20 parts on Flos Carthami, 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of the Fructus Kochiae, 10～20 parts of Flos Loniceraes, 10～20 parts of Fructus Psoraleaes, 1～10 part of Scolopendra; Various raw materials in part by weight ratios are in the external used medicine: 10～30 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Arnebiae (Radix Lithospermi)s, 10～30 parts of Rhizoma Smilacis Glabraes, 10～30 parts of Fructus Cnidiis, 10～30 parts of Rhizoma Drynariae, 10～30 parts of Cortex Phellodendris, 10～30 parts of Cortex Dictamnis, 10～30 parts in Flos Sophorae, 10～30 parts of Herba Hedyotidis Diffusaes, 1～10 part of Zaocys, 1～10 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～30 parts in sulfur.

2. according to the psoriatic Chinese medicine composition of the described treatment of claim 1, it is characterized in that, various raw materials in part by weight ratios are in the described endo-medicine: 10～15 parts of Radix Salviae Miltiorrhizaes, 10～15 parts of Radix Angelicae Sinensis, 10～15 parts of Herba Ecliptaes, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Radix Scutellariaes, 10～15 parts of the Radixs Astragali, 10～20 parts of Cortex Moutans, 10～20 parts of Herba Patriniae, 10～20 parts of Caulis Spatholobis, 10～20 parts on Flos Carthami, 10～20 parts of Rhizoma Chuanxiongs, 10～20 parts of the Fructus Kochiae, 10～20 parts of Flos Loniceraes, 10～20 parts of Fructus Psoraleaes, 1～5 part of Scolopendra; Various raw materials in part by weight ratios are in the external used medicine: 10～20 parts of Radix Sophorae Flavescentiss, 10～20 parts of Radix Arnebiae (Radix Lithospermi)s, 10～20 parts of Rhizoma Smilacis Glabraes, 10～20 parts of Fructus Cnidiis, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Cortex Phellodendris, 10～20 parts of Cortex Dictamnis, 10～20 parts in Flos Sophorae, 10～20 parts of Herba Hedyotidis Diffusaes, 1～5 part of Zaocys, 1～5 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～20 parts in sulfur.

3. according to the psoriatic Chinese medicine composition of the described treatment of claim 1, it is characterized in that, various raw materials in part by weight ratios are in the described endo-medicine: 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of Herba Ecliptaes, 10～20 parts of Rhizoma Drynariae, 10～20 parts of Radix Scutellariaes, 10～20 parts of the Radixs Astragali, 10～15 parts of Cortex Moutans, 10～15 parts of Herba Patriniae, 10～15 parts of Caulis Spatholobis, 10～15 parts on Flos Carthami, 10～15 parts of Rhizoma Chuanxiongs, 10～15 parts of the Fructus Kochiae, 10～15 parts of Flos Loniceraes, 10～15 parts of Fructus Psoraleaes, 1～8 part of Scolopendra; Various raw materials in part by weight ratios are in the external used medicine: 10～25 parts of Radix Sophorae Flavescentiss, 10～25 parts of Radix Arnebiae (Radix Lithospermi)s, 10～25 parts of Rhizoma Smilacis Glabraes, 10～25 parts of Fructus Cnidiis, 10～25 parts of Rhizoma Drynariae, 10～25 parts of Cortex Phellodendris, 10～25 parts of Cortex Dictamnis, 10～25 parts in Flos Sophorae, 10～25 parts of Herba Hedyotidis Diffusaes, 1～7 part of Zaocys, 1～7 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～25 parts in sulfur.

4. according to the psoriatic Chinese medicine composition of the described treatment of claim 1, it is characterized in that, various raw materials in part by weight ratios are in the described endo-medicine: 15～20 parts of Radix Salviae Miltiorrhizaes, 15～20 parts of Radix Angelicae Sinensis, 15～20 parts of Herba Ecliptaes, 15～20 parts of Rhizoma Drynariae, 15～20 parts of Radix Scutellariaes, 15～20 parts of the Radixs Astragali, 15～20 parts of Cortex Moutans, 15～20 parts of Herba Patriniae, 15～20 parts of Caulis Spatholobis, 15～20 parts on Flos Carthami, 15～20 parts of Rhizoma Chuanxiongs, 15～20 parts of the Fructus Kochiae, 15～20 parts of Flos Loniceraes, 15～20 parts of Fructus Psoraleaes, 1～8 part of Scolopendra; Various raw materials in part by weight ratios are in the external used medicine: 10～15 parts of Radix Sophorae Flavescentiss, 10～15 parts of Radix Arnebiae (Radix Lithospermi)s, 10～15 parts of Rhizoma Smilacis Glabraes, 10～15 parts of Fructus Cnidiis, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Cortex Phellodendris, 10～15 parts of Cortex Dictamnis, 10～15 parts in Flos Sophorae, 10～15 parts of Herba Hedyotidis Diffusaes, 1～6 part of Zaocys, 1～6 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 10～15 parts in sulfur.

5. one kind as the preparation method of the psoriatic Chinese medicine composition of treatment as described in each in the claim 1～4, it is characterized in that, described endo-medicine dosage form is a tablet, its preparation method may further comprise the steps: the Scolopendra of getting described ratio of weight and number is used soak with ethanol, alcohol heating reflux extracts in the alcohol reflux jar, extracts three times; Filtrate merges, stand for standby use; All the other described components are mixed by proportioning, drop into pulverizer and be ground into fine powder, put into the acid and alkali-resistance infusion kettle after fine powder sieves, at normal temperatures and pressures, flooded 10～20 days with ethanol is common, reheat extracts, carry out squeeze and filter with medicinal residues, get filtrate after the separation, mixed with aforementioned extracting solution then; Be concentrated into relative density and be 1.06 concentrated solution, add starch and stir, after the tabletting oven dry tablet.

6. one kind as the preparation method of the psoriatic Chinese medicine composition of treatment as described in each in the claim 1～4, it is characterized in that the endo-medicine dosage form is a capsule, and its preparation method may further comprise the steps:

A. Scolopendra being put into ethanol heat carries 3 times.

D. with thick paste at hothouse in dry below 60 ℃, the medicine piece;

7. according to preparation method described in the claim 6, it is characterized in that among described step a and the step b, the raw medicinal material of getting described ratio of weight and number adds in 10 times of amount ethanol, heating and refluxing extraction, each 1～2 hour, filtrate is merged, get medicinal liquid; Extracting solution is left standstill.

8. according to preparation method described in the claim 6, it is characterized in that, among the described step c, above-mentioned two kinds of extracting solution are merged, will merge in the back 2 times extracting solution suction concentrating under reduced pressure jar, reclaim ethanol earlier, be decompressed to 0.03-0.08MPa again, temperature remains on 60-80 ℃, and being concentrated into relative density is 1.20, the extractum that temperature to 60 is ℃-70 ℃.

9. one kind as the preparation method of the psoriatic Chinese medicine composition of treatment as described in each in the claim 1～4, it is characterized in that the dosage form of described external used medicine is a liniment, and its preparation method may further comprise the steps:

Earlier the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) and Zaocys are put into the ethanol heating extraction three times, with the extracting solution stand for standby use;

10. according to the psoriatic Chinese medicine composition of each described treatment in the claim 1～4, it is characterized in that,

The dosage form of described endo-medicine is: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, pill, powder, sublimed preparation, solution, injection, suppository, plaster, cream or drop;

The dosage form of described external used medicine is: unguentum, spray, liniment, ointment or emplastrum.