CN108498099A - Flexible alveolar obtains system and alveolar acquisition methods - Google Patents

Flexible alveolar obtains system and alveolar acquisition methods Download PDF

Info

Publication number
CN108498099A
CN108498099A CN201810300829.1A CN201810300829A CN108498099A CN 108498099 A CN108498099 A CN 108498099A CN 201810300829 A CN201810300829 A CN 201810300829A CN 108498099 A CN108498099 A CN 108498099A
Authority
CN
China
Prior art keywords
alveolar
module
signal
sound
voice signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810300829.1A
Other languages
Chinese (zh)
Other versions
CN108498099B (en
Inventor
冯雪
王峰乐
付际
金鹏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsinghua University
Original Assignee
Tsinghua University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsinghua University filed Critical Tsinghua University
Priority to CN201810300829.1A priority Critical patent/CN108498099B/en
Publication of CN108498099A publication Critical patent/CN108498099A/en
Application granted granted Critical
Publication of CN108498099B publication Critical patent/CN108498099B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/085Measuring impedance of respiratory organs or lung elasticity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816Measuring devices for examining respiratory frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/742Details of notification to user or communication with user or patient ; user input means using visual displays
    • A61B5/7445Display arrangements, e.g. multiple display units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0204Acoustic sensors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

This disclosure relates to which flexible alveolar obtains system and alveolar acquisition methods, including sound module, sensor assembly, signal processing and transmission module, computing module.Sound module sends out the first voice signal of different frequency;Sensor assembly receives lung because the first voice signal generates the second sound signal that vibration is sent out;Signal processing and transmission module, which convert the second sound signal, to be generated third voice signal and is transmitted to the third voice signal, computing module receives the third voice signal, the frequency of the third voice signal is calculated, and alveolar is calculated according to the frequency of the third voice signal.By the cooperation of each module, the disclosure can obtain the alveolar size of patient/user quickly, in real time, be monitored in real time to the alveolar size of patient/user.

Description

Flexible alveolar obtains system and alveolar acquisition methods
Technical field
This disclosure relates to which medical instruments field more particularly to a kind of flexible alveolar obtain system and alveolar acquisition Method.
Background technology
Mechanical ventilation (MV) is the main support means of respiratory failure caused by a variety of causes.The purpose of mechanical ventilation be for Body makes respiratory muscle be rested while providing enough gas exchanges.However, it can also cause respiratory muscle associated lung injury (VALI).The appearance of ventilator-associated lung injury and then is caused due to ventilating when Pulmonary volume (absolute value) increases Rupture of alveoli, gas leakage and various wind-contusions (e.g., pneumothorax, mediastinal emphysema and pneumoderm).It can directly (damage each simultaneously Kind cell) or (cell-signaling pathways of activation epithelial cell, endothelial cell or inflammatory cell) cause various intracellular Jie indirectly The release of matter.Certain medium energy coup injury lung tissues;Certain media can make lung gradually form pulmonary fibrosis.Other media Then as molecule of going back to the nest cell (such as neutrophil leucocyte) is assembled to lung, the molecule that the cell assembled to lung is released The injury of bigger can be caused to lung.
Therefore monitoring alveolar ventilation when degrees of expansion namely alveolar volume to carry out mechanical ventilation patient for very It is important.
Invention content
In view of this, the present disclosure proposes a kind of flexible alveolars to obtain system, the flexibility alveolar obtains system System includes:
Sound module, the first voice signal for generating different frequency;
Sensor assembly, the second sound signal transmitted for receiving lung, the second sound signal are lung because of institute It states the first voice signal and generates the voice signal that vibration is sent out;
Signal processing and transmission module are electrically connected to the sensor assembly, for converting the second sound signal Third voice signal is generated, and the third voice signal is transmitted, the third signal is digital signal;And
Computing module is electrically connected to the signal processing and transmission module, for receiving the third voice signal, calculates The frequency of the third voice signal, and alveolar is calculated according to the frequency of the third voice signal.
In one possible implementation, the sensor assembly includes multiple sound transducers, the multiple sound Sensor is made of sensing element and resonant cavity respectively, and sensing element is located in resonant cavity, and the sensing element is by multiple MEMS Microphone, electret microphone or their combination are made.
In one possible implementation, the sensor assembly is arranged in the supporter for being pasted on lung surface, institute It states supporter to manufacture using flexible material, the supporter includes flexible board and flexible package layer, the sensor assembly setting In on the flexible board, the flexible package layer is for encapsulating the sensor assembly and flexible board.
In one possible implementation, the flexible material is polyimides.
In one possible implementation, the signal processing and transmission module by wired or wireless mode by institute Third signal transmission is stated to the computing module, wherein the wireless mode includes bluetooth, WiFi, GPRS, 3G or 5G.
In one possible implementation, it further includes display module that the flexible alveolar, which obtains system, described aobvious Show that module is electrically connected to the computing module, for showing the alveolar and/or the frequency.
In one possible implementation, it further includes control module that the flexible alveolar, which obtains system, the control Molding block is electrically connected to the sound module and display module, the work for controlling the sound module and display module.
In one possible implementation, alveolar is calculated according to the frequency of the third voice signal, including:
The alveolar is calculated according to the first formula, first formula is:
Wherein, f0For the frequency of the third voice signal, c is the velocity of sound, and S is the face in the bronchiole section for connecting alveolar Product, d are the diameters in the bronchiole section for connecting alveolar, and l is the length for the bronchiole for connecting alveolar, and V is that the alveolar holds Product.
According to the one side of the disclosure, the disclosure also proposed a kind of alveolar acquisition methods, which is characterized in that described Method includes:
Sound module generates the first voice signal of different frequency;
Sensor assembly receives the second sound signal that lung is transmitted, and the second sound signal is lung because of the first sound Signal generates the voice signal that vibration is sent out;
Signal processing and transmission module, which convert the second sound signal, generates third voice signal and to the third Voice signal is transmitted, and the third signal is digital signal;And
Computing module receives the third voice signal, calculates the frequency of the third voice signal, and according to described the The frequency of three voice signals calculates alveolar.
In one possible implementation, this method further includes:
Display module shows the alveolar and the frequency;And
Control module controls the work of the sound module and display module.
The technical scheme provided by this disclosed embodiment can include the following benefits:Sound module sends out different frequency The first voice signal;Sensor assembly receives the second sound signal transmitted after lung is vibrated because of the first voice signal;Signal Processing and transmission module, which convert the second sound signal, to be generated third voice signal and is carried out to the third voice signal Transmission, computing module receive the third voice signal, calculate the frequency of the third voice signal, and according to the third sound The frequency of sound signal calculates alveolar, and by the cooperation of each module, the disclosure can obtain patient/user's quickly, in real time Alveolar size monitors the alveolar size of patient/user in real time.
According to below with reference to the accompanying drawings to detailed description of illustrative embodiments, the other feature and aspect of the disclosure will become It is clear.
Description of the drawings
Including in the description and the attached drawing of a part for constitution instruction and specification together illustrate the disclosure Exemplary embodiment, feature and aspect, and for explaining the principles of this disclosure.
Fig. 1 shows that the flexible alveolar of one embodiment of the disclosure obtains the module diagram of system.
Scene graph is used Fig. 2 shows flexible alveolar acquisition system shown in Fig. 1.
Fig. 3 (a) is the vertical view of sensor assembly 12, and Fig. 3 (b) is the front view of sensor assembly 12, and Fig. 3 (c) is shown The model schematic of bronchiole and its alveolar of connection.
Fig. 4 is that flexible volume obtains the corresponding part-structure schematic diagram of system module schematic diagram.
Fig. 5 shows that the flexible alveolar of the another embodiment of the disclosure obtains the module diagram of system.
Fig. 6 shows that the flexible alveolar of the another embodiment of the disclosure obtains the module diagram of system.
Fig. 7 shows a kind of flow chart for the alveolar acquisition methods obtaining system based on flexible alveolar.
Specific implementation mode
Various exemplary embodiments, feature and the aspect of the disclosure are described in detail below with reference to attached drawing.It is identical in attached drawing Reference numeral indicate functionally the same or similar element.Although the various aspects of embodiment are shown in the accompanying drawings, remove It non-specifically points out, it is not necessary to attached drawing drawn to scale.
Dedicated word " exemplary " means " being used as example, embodiment or illustrative " herein.Here as " exemplary " Illustrated any embodiment should not necessarily be construed as preferred or advantageous over other embodiments.
In addition, in order to better illustrate the disclosure, numerous details is given in specific implementation mode below. It will be appreciated by those skilled in the art that without certain details, the disclosure can equally be implemented.In some instances, for Method, means, element and circuit well known to those skilled in the art are not described in detail, in order to highlight the purport of the disclosure.
Fig. 1 shows that the flexible alveolar of one embodiment of the disclosure obtains the module diagram of system.
As shown in Figure 1, flexibility alveolar acquisition system includes:Sound module 11, sensor assembly 12, signal processing And transmission module 13 and computing module 14.Wherein, sensor assembly 12, signal processing and transmission module 13, and calculate mould Block 14 is sequentially connected electrically, and the sound that the sound that sound module 11 is sent out generates after causing lung to be vibrated can be connect by sensor assembly 12 It receives.
Sound module 11, the first voice signal for generating different frequency.
In one possible implementation, sound module 11 can be switched by power supply, is carried the chip of I/O pins, is raised These elements can be divided into module by the compositions such as sound device in some embodiments, for example, can be divided into signal generator module and Loudspeaker module, signal generator module can be by switching, the compositions such as chip with I/O pins, for generating pulse electrical signal.It raises Sound device module includes loud speaker, is made a sound by the driving of signal generator module.The chip can be the use specially designed Can also be 8 integrated chips of such as AT89 series and other types of integrated chip in the chip for generating pulse signal.
In a kind of possible embodiment, the mode that sound module 11 generates the first voice signal of different frequency can For:Chip is controlled by program, and output pulse electrical signal drive the speaker generates first voice signal.
In a kind of possible embodiment, sound module 11 can also generate the of different frequency by way of frequency sweep One voice signal.For example, can be by writing program to chip so that chip generates swept-frequency signal, and swept-frequency signal driving is raised Sound device is to generate first voice signal.
In a kind of possible embodiment, the first voice signal may include discrete or continuous, different in certain frequency range The voice signal of frequency.
Please also refer to Fig. 2.
Fig. 2 is flexible alveolar acquisition system shown in Fig. 1 with scene graph.As shown in Fig. 2, 11 direction of sound module Mouth/nose of human body makes a sound signal, and voice signal can travel to lung, voice signal and lung's phase with air-flow through respiratory system Another voice signal is generated after interaction to be received by sensor assembly 12, and for example, the mode of the interaction can be to send out The voice signal that sound module 11 is sent out causes lung's vibration to generate another voice signal.
Sensor assembly 12, the second sound signal transmitted for receiving lung, second sound signal are lung because described in First voice signal generates the voice signal that vibration is sent out.
Also referring to Fig. 3 (a), Fig. 3 (b), Fig. 3 (c).
Fig. 3 (a) and Fig. 3 (b) shows that the sensor assembly schematic diagram according to one embodiment of the disclosure, wherein Fig. 3 (a) are to pass The vertical view of sensor module 12, Fig. 3 (b) are the front view of sensor assembly 12, and Fig. 3 (c) shows bronchiole and its connection Alveolar model schematic.
In a kind of possible embodiment, sensor assembly 12 includes multiple sound transducers, and sound transducer can divide It is not made of sensing element 21 and resonant cavity 22, sensing element 21 is located in resonant cavity 22, and sensing element 21 can be by multiple MEMS Microphone, electret microphone or their combination are made.
In a kind of possible embodiment, sensor assembly 12 is arranged on the supporter 2 for being pasted on lung surface, branch Support body 2 is manufactured using flexible material, including flexible board 24 and flexible package layer 23, sensor assembly 12 are set to the flexible board On 24, flexible package layer 23 is for encapsulating the sensor assembly 12 and flexible board 24.Flexible package layer 23 can cover flexible board 24.For example, flexible material can be polyimides, and supporter 2 can be with flexible board made of polyimides 24 and flexibility Encapsulated layer 23 is made.Implementation in the above manner can greatly increase system flexibility and gas permeability.In other embodiment In, flexible material can select as needed, and the present invention does not limit.
In a kind of possible embodiment, the outer profile of resonant cavity 22 can be horn-like or halfpace shape, resonant cavity 22 Inner hollow forms cavity, to play the role of preferably collection and concentration to sound.22 both ends of resonant cavity are opening, smaller Opening is securable to flexible board 24, and sensing element 21 can be in the range of smaller opening surrounds, and is arranged on flexible board 24. In use, the larger open of resonant cavity 22 can be pasted on lung, collect the voice signal of lung's outflow, the biography in resonant cavity 22 21 acoustic signals of sensing unit, and voice signal is converted into electric signal from sound wave, it will be made by the circuit on flexible board 24 For electric signal transmission of sound signals to signal processing and transmission module 13.Signal processing and transmission module 13 can be with flexible circuits Mode realized on flexible board 24.
In a kind of possible embodiment, the first voice signal of the multi-frequency that sound module 11 is sent out can pass through people The respiratory system of body, such as trachea and bronchus, travel to lung.For example, sound module 11 can be close to or direction Oral area, the nose sounding of patient/user, the voice signal that sound module 11 is sent out can be propagated by the respiratory system of human body Lung.The lung of human body includes the alveolar that size shape differs, and the first voice signal with lung, alveolar after interacting It generates second sound signal to be captured by sensor assembly 12, for example, the mode of the interaction can be that sound module 11 is sent out The first voice signal gone out causes lung's vibration to generate second sound signal.
In a kind of possible embodiment, the voice signal that sensor assembly 12 captures is related with alveolar size Principle be that the alveolar in human body is connected with bronchiole, and bronchiole and its end alveolar are equivalent to a Hai Muhuo Hereby acoustic resonator (Fig. 3 (c)), acoustic impedance is related with alveolar.Therefore the size of alveolar can influence the voice signal received Frequency spectrum, i.e., after voice signal is received by alveolar, can interact with alveolar, different size of alveolar will produce different frequencies Spectrum response.The degrees of expansion of alveolar at this can be judged by the frequency spectrum of the voice signal of analyte sensors module 12.Therefore, quilt The second sound signal and alveolar that sensor assembly 12 receives are highly relevant.
Signal processing and transmission module 13, are electrically connected to the sensor assembly, for turning the second sound signal It changes and generates third voice signal and the third voice signal is transmitted, third signal is digital signal.
In a kind of possible embodiment, second sound signal is analog signal, and signal processing and transmission module 13 will Second sound signal is converted to digital signal, and process includes but not limited to that second sound signal is carried out denoising, amplification, A/D Conversion, second sound signal after treatment become third voice signal, which is digital signal, is conveniently deposited Storage and transmission.
In a kind of possible embodiment, third signal is transmitted by signal processing and transmission module 13, for example, can It is transmitted by wired mode.When being transmitted by wired mode, signal processing and transmission module 13 pass through letter Number line is electrically connected to computing module 14, by third signal transmission to computing module 14.Signal processing and transmission module 13 can also lead to It crosses and is wirelessly transmitted third signal, wirelessly including but not limited to bluetooth, WiFi, GPRS, 3G or 5G, with And other wireless transmission methods.It should be noted that in the present embodiment, signal processing and two processes are transmitted as, he Can be integrated in the same module, two modules can also be separated into, such as signal processing and transmission module 13 can be divided For signal processing module, transmission module, certainly, the effect of both modes is similar.In other embodiments, at signal Reason and transmission module 13 can also store third voice signal including memory, to improve the efficiency of data transmission, deposit Reservoir can be by any kind of volatibility or non-volatile memory device or combination thereof realization, such as static random-access Memory (SRAM), electrically erasable programmable read-only memory (EEPROM), Erasable Programmable Read Only Memory EPROM (EPROM), Programmable read only memory (PROM), read-only memory (ROM), magnetic memory, flash memory, disk or CD.
Computing module 14 is electrically connected to the signal processing and transmission module 13, for receiving the third voice signal, The frequency of the third voice signal is calculated, and alveolar is calculated according to the frequency of the third voice signal.
In a kind of possible embodiment, after computing module 14 receives third voice signal, the side of frequency sweep can be passed through Method obtains the frequency response curve of third voice signal, is obtained from the frequency response curve of third voice signal by the methods of Fourier transformation The spectral characteristic for taking the third voice signal obtains its frequency by the spectral characteristic of the third voice signal, and is counted according to formula 1 Calculate the corresponding alveolar of the frequency.
In equation 1, f0For the frequency of the third voice signal, c is the velocity of sound, and S is the bronchiole section for connecting alveolar The area in face, d are the diameters in the bronchiole section for connecting alveolar, and l is the length for the bronchiole for connecting alveolar, and V is described Alveolar.Wherein, f is removed0And outside V, other such as c, S, d, the parameters such as l are known parameters, S, d, and l can pass through practical measurement Or empirical value obtains.
In a kind of possible embodiment, computing module 14 can further comprise memory, processor, computing module 14 The data that signal processing and transmission module 13 transmit are stored by memory, and memory can be by any kind of volatibility or non- Volatile storage devices or combination thereof realize that, such as static RAM (SRAM), electrically erasable is only Reading memory (EEPROM), Erasable Programmable Read Only Memory EPROM (EPROM), programmable read only memory (PROM) are read-only to deposit Reservoir (ROM), magnetic memory, flash memory, disk or CD.Processor can be by one or more application application-specific integrated circuit (ASIC), digital signal processor (DSP), digital signal processing appts (DSPD), programmable logic device (PLD), scene can Gate array (FPGA), controller, microcontroller, microprocessor or other electronic components are programmed to realize.When signal processing and transmission Module 13 wirelessly transmission data when, computing module may also include wireless receiving module, for example, bluetooth receive mould The receiving module corresponding with the transmission mode of signal processing and transmission module transmission data such as block, WiFi receiving modules.
Computing module 14 can be realized by specialized hardware, can also pass through all-purpose computer and other ends with processing function End equipment is realized, or is realized by network calculations Service Source.
Referring to FIG. 4, Fig. 4, which is flexible volume, obtains the corresponding part-structure schematic diagram of system module schematic diagram.
As shown in figure 4, the part-structure schematic diagram includes sound module 11, sensor assembly 12, signal processing and transmission Module 13 and supporter 2, sensor assembly 12 may be disposed on supporter 2, and signal processing and transmission module 13 can also be arranged In on supporter.
System is obtained based on the above flexible alveolar, the real time data of patient/user's alveolar can be obtained.
Fig. 5 shows that the flexible alveolar of the another embodiment of the disclosure obtains the module diagram of system.
As shown in figure 5, flexible alveolar acquisition system includes:Sound module 11, sensor assembly 12, signal processing and Transmission module 13, computing module 14 and display module 15, sensor assembly 12, signal processing and transmission module 13 calculate mould Block 14 and display module 15 are sequentially connected electrically, and the sound that the sound that sound module 11 is sent out generates after causing lung to be vibrated can quilt Sensor assembly 12 receives.
Sound module 11, the first voice signal for generating different frequency.
For sensor assembly 12 for receiving the second sound signal that lung is transmitted, second sound signal is lung because of described the One voice signal generates the voice signal that vibration is sent out.
Signal processing and transmission module 13, are electrically connected to the sensor assembly, for turning the second sound signal It changes and generates third voice signal and the third voice signal is transmitted.
Computing module 14 is electrically connected to the signal processing and transmission module 13, for receiving the third voice signal, The frequency of the third voice signal is calculated, and alveolar is calculated according to the frequency of the third voice signal.
Sound module 11 in Fig. 5, sensor assembly 12, signal processing and transmission module 13, computing module 14 and Fig. 1 phases Together, here, being repeated no more to its specific introduction, the description before can refer to.
Display module 15, for showing alveolar and/or the frequency that computing module 14 is calculated.
In a kind of possible embodiment, display module 15 can be LED display, LCD display, etc..Show mould Block 15 shows that the mode of alveolar and its corresponding frequency can be real-time display, when sound module continuously send out it is more When the sound of kind different frequency, flexible alveolar obtains system and has been under operating mode, therefore the volume of alveolar is not The update stopped, it will be understood that patient/user during breathing, alveolar can diastole, deflation state between become back and forth Dynamic, the volume of alveolar is also among ceaselessly variation.
Among a kind of possible embodiment, display module 15, which can be grouped the corresponding alveolar of display lung different zones, to be held Product size.By description before it is found that sensor assembly 12 is arranged including multiple sensors on supporter 2, supporter 2 sticks In lung surface.The position of different Sensor monitorings is different, therefore can be as required to the sensor on sensor assembly 12 It is grouped, and display is grouped to the alveolar after grouping, shown in this manner more intuitive.Grouping Mode can be arranged as required to, and can be grouped according to the structure of lung.
System is obtained based on the above flexible alveolar, the real time data of patient/user's alveolar can be obtained, and show Show that, to human observer, human observer can facilitate, be visually observed that the variation of patient/user's alveolar.
Fig. 6 shows that the flexible alveolar of the another embodiment of the disclosure obtains the module diagram of system.
As shown in fig. 6, flexible alveolar acquisition system includes:Sound module 11, sensor assembly 12, signal processing and Transmission module 13, computing module 14, display module 15 and control module 16, sensor assembly 12, signal processing transmission module 13, computing module 14, display module 15 and control module 16 are sequentially connected electrically, and the sound that sound module 11 is sent out causes lung to be shaken The sound sent out after dynamic can be received by sensor assembly 12.
Sound module 11, the first voice signal for generating different frequency.
For sensor assembly 12 for receiving the second sound signal that lung is transmitted, second sound signal is lung because of described the One voice signal generates the voice signal that vibration is sent out.
Signal processing and transmission module 13, are electrically connected to the sensor assembly, for turning the second sound signal It changes and generates third voice signal and the third voice signal is transmitted.
Computing module 14 is electrically connected to the signal processing and transmission module 13, for receiving the third voice signal, The frequency of the third voice signal is calculated, and alveolar is calculated according to the frequency of the third voice signal.
Display module 15 is electrically connected to computing module 14, for showing the alveolar and/or the frequency.
Refering to Fig. 6, the sound module 11 in Fig. 6, sensor assembly 12, signal processing and transmission module 13, computing module 14, display module 15 is identical as Fig. 1, Fig. 5, here, being repeated no more to its specific introduction, the description before can refer to.
Among a kind of possible embodiment, control module 16 is electrically connected to sound module, for controlling the sounding The work of module 11 and display module 15.For example, control module 16 can control the sound that sound module 11 sends out different frequency, It can also control and module 11 occurs send out the sound of specific frequency, when can also control sound module 11 and making a sound lasting Between, etc..It includes but not limited to the third that computing module 14 is calculated that control module 16, which can control the display of display module 15, The frequency of voice signal and the alveolar calculated according to the frequency.It should be understood that sensor assembly 12, signal processing and transmission Module 13, computing module 14 may each be the relationship of electrical connection between display module 15, and therefore, control module 16 can also be controlled Make the work of other modules, that is, control module 16 can control the work that entire flexible alveolar obtains system.It should illustrate , above-mentioned " work " is not limited to the work that each module itself should be completed, can also include control module 16 can by program, Instruction controls the work that each module carries out, for example, control module 16 can reset, reset, closing, enabling each module.
Among a kind of possible embodiment, control module 16 can be by one or more application application-specific integrated circuit (ASIC), digital signal processor (DSP), digital signal processing appts (DSPD), programmable logic device (PLD), scene can Gate array (FPGA), controller, microcontroller, microprocessor or other electronic components are programmed to realize.
It should be noted that the setting for obtaining each module of system to flexible alveolar above is exemplary, this field Technical staff it is understood that the disclosure answer it is without being limited thereto.In fact, user completely can be according to personal like and/or practical application Scene flexibly sets the modules that flexible alveolar obtains system.
Further, the disclosure also provides a kind of testing procedure and embodiment of flexible alveolar acquisition system, should Testing procedure may include with embodiment:
Flexible alveolar acquisition system assembles are good, and preparation starts to test;
Supporter 2 is fitted in the lung of patient/user;
Sound module 11 generates pulse signal, and sound module 11 emits pulse sound signal;
Sensor assembly 12 starts to acquire corresponding voice signal;
Signal processing and transmission module 13 carry out processing transmission to the voice signal of reception;
Monitoring personnel can see the Relative volumes of different zones alveolar on display module 15.
System is obtained based on the above flexible alveolar, the real time data of patient/user's alveolar can be obtained, and show Show that, to human observer, human observer can facilitate, be visually observed that the variation of patient/user's alveolar, while control module 16 Presence, whole system and each module can be controlled.
When measurement, sound spectrum when people exhales, then sound spectrum when measuring air-breathing can be first measured, compares to obtain people and exhale Frequency spectrum difference when suction, you can obtain alveolar opening and closing volume range.
Fig. 7 shows a kind of flow chart for the alveolar acquisition methods obtaining system based on flexible alveolar.
- Fig. 6 refering to fig. 1, flexible alveolar obtain system and may include sound module 11, sensor assembly 12, at signal Reason and transmission module 13, computing module 14, display module 15 and control module 16.
As shown in fig. 7, alveolar acquisition methods include:
Step S110, sound module generate the first voice signal of different frequency.
Step S120, sensor assembly receive the second sound signal that lung is transmitted, and the second sound signal is lung Because first voice signal generates the voice signal that vibration is sent out.
The second sound signal is converted and generates third voice signal and right by step S130, signal processing and transmission module The third voice signal is transmitted, and the third signal is digital signal.
Step S140, computing module receive the third voice signal, calculate the frequency of the third voice signal, and root Alveolar is calculated according to the frequency of the third voice signal.
In one possible implementation, alveolar is calculated according to the frequency of the third voice signal may include:
Alveolar is calculated according to the first formula, first formula is:
Wherein, f0For the frequency of the third voice signal, c is the velocity of sound, and S is the face in the bronchiole section for connecting alveolar Product, d are the diameters in the bronchiole section for connecting alveolar, and l is the length for the bronchiole for connecting alveolar, and V is that the alveolar holds Product.
Further, this method may also comprise the following steps::
Display module shows the alveolar and the frequency;And
Control module controls the work of the sound module and display module.
It should be noted that although describing alveolar acquisition methods, people in the art using step as example Member it is understood that the disclosure answer it is without being limited thereto.In fact, user completely can be according to personal like and/or practical application scene spirit The step of setting this method living.
Based on above-mentioned flexible alveolar acquisition methods, the alveolar of patient/user can be monitored in real time.
The presently disclosed embodiments is described above, above description is exemplary, and non-exclusive, and It is not limited to disclosed each embodiment.Without departing from the scope and spirit of illustrated each embodiment, for this skill Many modifications and changes will be apparent from for the those of ordinary skill in art field.The selection of term used herein, purport In the principle, practical application or technological improvement to the technology in market for best explaining each embodiment, or this technology is made to lead Other those of ordinary skill in domain can understand each embodiment disclosed herein.

Claims (10)

1. a kind of flexibility alveolar obtains system, which is characterized in that the flexibility alveolar obtains system and includes:
Sound module, the first voice signal for generating different frequency;
Sensor assembly, the second sound signal transmitted for receiving lung, the second sound signal are lung because of described the One voice signal generates the voice signal that vibration is sent out;
Signal processing and transmission module are electrically connected to the sensor assembly, are generated for converting the second sound signal Third voice signal, and the third voice signal is transmitted, the third signal is digital signal;And
Computing module is electrically connected to the signal processing and transmission module, for receiving the third voice signal, described in calculating The frequency of third voice signal, and alveolar is calculated according to the frequency of the third voice signal.
2. flexibility alveolar according to claim 1 obtains system, which is characterized in that the sensor assembly includes more A sound transducer, the multiple sound transducer are made of sensing element and resonant cavity respectively, and sensing element is located at resonant cavity Interior, the sensing element is made of multiple MEMS microphones, electret microphone or their combination.
3. flexibility alveolar according to claim 2 obtains system, which is characterized in that the sensor assembly setting exists It is pasted on the supporter of lung surface, the supporter is manufactured using flexible material, and the supporter includes flexible board and flexibility Encapsulated layer, the sensor assembly are set on the flexible board, and the flexible package layer is for encapsulating the sensor assembly And flexible board.
4. flexibility alveolar according to claim 3 obtains system, which is characterized in that the flexible material is that polyamides is sub- Amine.
5. obtaining system according to claim 1-4 any one of them flexibility alveolars, which is characterized in that the signal processing And transmission module by wired or wireless mode by the third signal transmission to the computing module, wherein it is described wireless Mode includes bluetooth, WiFi, GPRS, 3G or 5G.
6. flexibility alveolar according to claim 5 obtains system, which is characterized in that the flexibility alveolar obtains System further includes display module, and the display module is electrically connected to the computing module, for show the alveolar and/or The frequency.
7. flexibility alveolar according to claim 6 obtains system, which is characterized in that the flexibility alveolar obtains System further includes control module, and the control module is electrically connected to the sound module and display module, for controlling the hair The work of sound module and display module.
8. flexibility alveolar according to claim 1 obtains system, which is characterized in that according to the third voice signal Frequency calculate alveolar, including:
The alveolar is calculated according to the first formula, first formula is:
Wherein, f0For the frequency of the third voice signal, c is the velocity of sound, and S is the area in the bronchiole section for connecting alveolar, d It is the diameter in the bronchiole section for connecting alveolar, l is the length for the bronchiole for connecting alveolar, and V is the alveolar.
9. a kind of alveolar acquisition methods, which is characterized in that the method includes:
Sound module generates the first voice signal of different frequency;
Sensor assembly receives the second sound signal that lung is transmitted, and the second sound signal is lung because of first sound Signal generates the voice signal that vibration is sent out;
Signal processing and transmission module, which convert the second sound signal, generates third voice signal and to the third sound Signal is transmitted, and the third signal is digital signal;And
Computing module receives the third voice signal, calculates the frequency of the third voice signal, and according to the third sound The frequency of sound signal calculates alveolar.
10. alveolar acquisition methods according to claim 9, which is characterized in that further include:
Display module shows the alveolar and the frequency;And
Control module controls the work of the sound module and display module.
CN201810300829.1A 2018-04-04 2018-04-04 Flexible alveolar volume acquisition system and alveolar volume acquisition method Active CN108498099B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810300829.1A CN108498099B (en) 2018-04-04 2018-04-04 Flexible alveolar volume acquisition system and alveolar volume acquisition method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810300829.1A CN108498099B (en) 2018-04-04 2018-04-04 Flexible alveolar volume acquisition system and alveolar volume acquisition method

Publications (2)

Publication Number Publication Date
CN108498099A true CN108498099A (en) 2018-09-07
CN108498099B CN108498099B (en) 2020-04-17

Family

ID=63380909

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810300829.1A Active CN108498099B (en) 2018-04-04 2018-04-04 Flexible alveolar volume acquisition system and alveolar volume acquisition method

Country Status (1)

Country Link
CN (1) CN108498099B (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100223987B1 (en) * 1996-12-31 1999-10-15 김덕중 Sound resonance diffuser with helmholtz type
US6190337B1 (en) * 1997-07-14 2001-02-20 Subacoustech Limited Dislodging or loosening mucus in a person's lungs
CN1498514A (en) * 2001-06-15 2004-05-19 特克斯特罗恩***公司 System and methods for sensing acoustic signal using micro-electronical system technology
CN102638753A (en) * 2012-03-16 2012-08-15 中北大学 MEMS (micro-electro-mechanical system) acoustic sensor based on graphene
US20120243377A1 (en) * 2011-03-21 2012-09-27 Teledyne Benthos, Inc. Gas-filled bubble sound source
CN102771142A (en) * 2011-02-21 2012-11-07 欧姆龙株式会社 Microphone
EP1622512B1 (en) * 2003-04-10 2013-02-27 Adidas AG Systems and methods for respiratory event detection
WO2017153907A1 (en) * 2016-03-10 2017-09-14 Rg Healthcare Pte Ltd. Microelectronic sensors for non-invasive monitoring of physiological parameters

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100223987B1 (en) * 1996-12-31 1999-10-15 김덕중 Sound resonance diffuser with helmholtz type
US6190337B1 (en) * 1997-07-14 2001-02-20 Subacoustech Limited Dislodging or loosening mucus in a person's lungs
CN1498514A (en) * 2001-06-15 2004-05-19 特克斯特罗恩***公司 System and methods for sensing acoustic signal using micro-electronical system technology
EP1622512B1 (en) * 2003-04-10 2013-02-27 Adidas AG Systems and methods for respiratory event detection
CN102771142A (en) * 2011-02-21 2012-11-07 欧姆龙株式会社 Microphone
US20120243377A1 (en) * 2011-03-21 2012-09-27 Teledyne Benthos, Inc. Gas-filled bubble sound source
CN102638753A (en) * 2012-03-16 2012-08-15 中北大学 MEMS (micro-electro-mechanical system) acoustic sensor based on graphene
WO2017153907A1 (en) * 2016-03-10 2017-09-14 Rg Healthcare Pte Ltd. Microelectronic sensors for non-invasive monitoring of physiological parameters

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JERRY YU: "Airway mechanosensors", 《RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY》 *
吕伯强等: "《电磁振荡·波动与辐射》", 31 December 1981 *
韩旭等: "基于亥姆霍兹共鸣器的声电转换***研究", 《压电与声光》 *
马大猷: "亥姆霍兹共鸣器", 《声学技术》 *

Also Published As

Publication number Publication date
CN108498099B (en) 2020-04-17

Similar Documents

Publication Publication Date Title
TW541160B (en) Apparatus and method for detecting very low frequency acoustic signals
TWI646942B (en) Lung sound monitoring device and lung sound monitoring method
JPS59165598A (en) Measuring device of bent characteristics of bented earphone
Wodicka et al. Measurement of respiratory acoustic signals: effect of microphone air cavity depth
Jang et al. Biomimetic artificial basilar membranes for next‐generation cochlear implants
CN107260206A (en) Electronic type stethoscope based on MEMS sound sensing principles
EP2265037A3 (en) Devices and transducers with cavity resonator to control 3-d characteristics/harmonic frequencies for all sound/sonic waves
Roy et al. A Simple technique for heart sound detection and real time analysis
CN108498099A (en) Flexible alveolar obtains system and alveolar acquisition methods
KR20180043292A (en) A respiratory function test system and a method for testing the respiratory function of such a system
CN106344064A (en) Audio signal acquisition device and method
CN109199353A (en) Electronic blood pressure monitor, blood pressure measuring method and electronic auscultation device
BR112021004719A2 (en) signal processing device with multiple acoustic electrical transducers
CN113925478A (en) Integrated flexible sensor for blood pressure measurement
CN206063399U (en) Auxiliary sputum ejector
Kirchner et al. Wearable system for measurement of thoracic sounds with a microphone array
DE102004008057A1 (en) Device for the oscillometric analysis of the airway impedance
CN208065176U (en) Forced oscillation pulmonary function test (pft) device
CN108652632A (en) Forced oscillation pulmonary function test (pft) device and method
JP2000060846A (en) Biological sound detector
CN103686499B (en) Bionic pickup
van der Torn et al. Aero-acoustics of silicone rubber lip reeds for alternative voice production in laryngectomees
JP3198239U (en) Device that encourages sleep posture change when detecting apnea during sleep
Minh et al. Design of Real-time and Low-cost Electronic Stethoscope
US12003914B2 (en) Vibroacoustic earbud

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant