CN108420984A - A kind of drug and preparation method thereof for treating oedema - Google Patents

A kind of drug and preparation method thereof for treating oedema Download PDF

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CN108420984A
CN108420984A CN201810405620.1A CN201810405620A CN108420984A CN 108420984 A CN108420984 A CN 108420984A CN 201810405620 A CN201810405620 A CN 201810405620A CN 108420984 A CN108420984 A CN 108420984A
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侯明
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Abstract

The invention discloses a kind of drugs and preparation method thereof for treating oedema, it is by wrinkled giant hyssop, the tuber of pinellia, Cortex Magnoliae Officinalis, Fructus Aurantii, Amomum cardamomum, campanulaceae, almond, Chinese Drug Gualouzi, Radix Angelicae Sinensis, brush-cherry seed, peach kernel, the fruit of Chinese wolfberry, Chinese ephedra, dried orange peel, the shell of areca nut, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig, umbellate pore furgus, cortex acanthopanacis, Chinese cassia tree, lepidium seed, perilla seed, waxgourd peel, the root of fangji, evodia rutaecarpa, Fructus Forsythiae, Cortex Magnoliae Officinalis, rhizoma imperatae, coix seed is prepared according to a certain weight ratio, drug of the present invention has lower gas Li Shui, during lower gas is wide, clearing damp and promoting diuresis, tonifying spleen benefit stomach, function of the eliminating dampness in, it is quick for treating oedema, good effect, it does not recur.

Description

A kind of drug and preparation method thereof for treating oedema
Technical field
The present invention relates to a kind of drugs and preparation method thereof for treating oedema, belong to the field of Chinese medicines.
Background technology
Oedema is excessive fluid retention in tissue space or body cavity, however commonly called oedema is referring in tissue space Body fluid increase, body fluid increases in body cavity, claims hydrops.Oedema can behave as locality or systemic, when anasarca often There is dropsy of serous cavity simultaneously, such as ascites, pleural effusion and pericardial effusion.Since western medicine side effect is big, people couple Effectively there are great demands for the Chinese medicine for the treatment of oedema, up to now, it has not been found that the related report about the present invention.
Invention content
Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment oedema Drug, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment oedema.
Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.
Drug of the present invention is selection wrinkled giant hyssop, the tuber of pinellia, Cortex Magnoliae Officinalis, Fructus Aurantii, Amomum cardamomum, campanulaceae, almond, Chinese Drug Gualouzi, Radix Angelicae Sinensis, Yu Li Benevolence, peach kernel, the fruit of Chinese wolfberry, Chinese ephedra, dried orange peel, the shell of areca nut, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig, umbellate pore furgus, cortex acanthopanacis, Chinese cassia tree, lepidium seed, Perilla seed, waxgourd peel, the root of fangji, evodia rutaecarpa, Fructus Forsythiae, Cortex Magnoliae Officinalis, rhizoma imperatae, coix seed are combined preparation, by these medicine groups It closes so that each efficacy of drugs generates synergistic effect, so as to effectively treat oedema.Wherein selection wrinkled giant hyssop is pungent because of its nature and flavor, Tepor enters lung, spleen, stomach, there is fast gas, and in, to ward off dirty, the function of clearing damp, cure cold summer-heat and damp, fever and chills, headache, chest gastral cavity ruffian, Vomiting and diarrhea, malaria, dysentery, halitosis.Select the tuber of pinellia be because its nature and flavor it is acrid in flavour and warm in nature, it is toxic, enter spleen, stomach, have it is eliminating dampness and eliminating phlegm, Stopping nausea and vomiting by lowering the adverse flow of QI, the function of clear ruffian dissipating bind control wet phlegm and cold drink vomiting, gastric disorder causing nausea, cough and phlegm, my diaphragm turgor, phlegm and headache, it is dizzy not It sleeps, outer subduing inflammation.It is to enter spleen, stomach, large intestine channel because its is bitter in taste acrid in flavour and warm in nature, there is middle benefit gas, lower gas, eliminating dampness, dissolving phlegm to select Cortex Magnoliae Officinalis Function, control chest and abdomen feeling of fullness distending pain, gastric disorder causing nausea, vomiting, place food do not disappear, sputum cough, cold-dampness rush down dysentery.It is because of its property to select Fructus Aurantii It is bitterly, it is cool, enter lung, spleen, large intestine channel, there is a relieving stagnant Qi, row phlegm, the function of disperse accumulation controls that chest diaphragm phlegm is stagnant, and the feeling of stuffiness in chest coerces swollen, dyspepsia, Gas is vomitted inverse, weight, rectal prolapse, the prolapse of uterus after diarrhea.It is to enter lung, the spleen channel because its nature and flavor is acrid in flavour and warm in nature, there is sector-style to select Amomum cardamomum, Warm stomach helps digestion, it is wide in function, control the stagnation of the circulation of vital energy, food stagnation is uncomfortable in chest, abdominal distension, and gas is dysphagic, spits inverse, gastric disorder causing nausea, malaria.Select campanulaceae It is to put down, enter lung, stomach because of its nature and flavor toil, there is an open the inhibited lung-energy, the function of eliminating the phlegm apocenosis controls exogenous cough, abscess of throat, Lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery abdominal pain.It is because its is bitter in taste to select almond, and temperature is toxic, enters lung, large intestine channel, there is eliminating the phlegm Cough-relieving is relievingd asthma, the function of ease constipation, controls exogenous cough, asthma is full, larynx numbness, dry constipation of intestines.Select Chinese Drug Gualouzi be because its nature and flavor it is sweet, Cold, return lung, stomach, large intestine channel have moistening lung for removing phlegm, the function of laxation defaecation to control cough caused by dryness phlegm and stick, dry constipation of intestines.Select Radix Angelicae Sinensis be because For its nature and flavor sweet, acrid, warm, enter the heart, liver, the spleen channel, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation to control irregular menstruation, passes through It is poly- to close abdominal pain , Disorder lump in the abdomen knots, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness difficulty just, fall and flutter after dysentery characterized by blood in the stool by weight, ulcer sores, metal-inflicted wound Damage.It is sweet and neutral because its nature and flavor is worked hard to select brush-cherry seed, enters spleen, intestine and small intestine warp, has and moisturize, laxation, lower gas, the work(of Li Shui Can, qi stagnation of large intestine is controlled, dry puckery obstructed, difficult urination, extensive abdominal edema, four limbs edema, tinea pedis.It is because its is bitter in taste to select peach kernel Sweet and neutral enters the heart, liver, large intestine channel, there is the blood-breaking row stasis of blood, moisturizes the function of sliding warp, controlling through closing , Disorder lumps in the abdomen, and pyreticosis stores blood, blood-arthralgia, malaria Disease, traumatic injury, blood stasis and swelling pain, the dry constipation of blood.It is to have a nourshing kidney because of its nature and flavor sweet and neutral to select the fruit of Chinese wolfberry, moistening lung, and tonifying liver is bright Purpose function controls liver-kidney Yin deficiency, and soreness and weakness of waist and knees is had a dizzy spell, and the more tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.Selecting Chinese ephedra is Because its nature and flavor is arduous, temperature enters lung, bladder warp, there is sweating, relievings asthma, the function of Li Shui, the cold table that cures the wound is real, and fever with chilliness is lossless, Headache nasal obstruction, arthralgia, cough and asthma, geomantic omen edema, difficult urination, the stupid numbness of ailment said due to cold or exposure, munbness, rubella itch.It selects Dried orange peel is that have regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm function to control chest gastral cavity turgor, deficiency of food because of its bitter in taste, acrid in flavour and warm in nature, return lung, the spleen channel It vomits and diarrhoea, coughing with a lot of sputum.Select the shell of areca nut be because its nature and flavor it is pungent, tepor, enter spleen, stomach, intestine and small intestine warp, have lower gas it is wide in, row water Function, control gastral cavity abdomen swollen ruffian, tinea pedis, oedema.It is to tremble with fear because its nature and flavor is sweet, enter bladder warp, advantageous water, excreting dampness is let out to select rhizoma alismatis The function of heat controls difficult urination, and oedema anus is full, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, hematuria.It is because of its property to select Rhizoma Atractylodis Macrocephalae Bitter sweet, warm enters spleen, stomach, there is a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating, burnout lacks gas, Empty swollen, diarrhea, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, spontaneous perspiration, and nausea is uneasy.It is because of its property to select Poria cocos Slightly sweet flavor puts down, enters the heart, spleen, lung channel, have eliminating dampness and diuresis, beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative to control difficult urination oedema distending pain, Phlegm and retained fluid cough is inverse, the sound of vomiting of vomitting, diarrhea, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select cassia twig be because of the pungent sweet, warm of its nature and flavor, enter bladder, the heart, Lung channel has sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control exterior syndrome due to wind-cold, and shoulder carries on the back podomere ache, obstruction of qi in the chest phlegm and retained fluid, Jing Bi Disorder lumps in the abdomen.It selects Umbellate pore furgus is put down, enters spleen, kidney, bladder warp, there is the function of diuresis excreting dampness because of its property slightly sweet flavor, controls difficult urination, oedema turgor, Tinea pedis, diarrhea drench, are turbid, under band.It is to return liver and kidney channel because of its property and flavor of peppery and warm, there is wind-damp dispelling, strengthen the bone to select cortex acanthopanacis, living The function of blood stasis eliminatings, controls wind-cold-dampness arthralgia, and muscle slides contraction urgency, oedema tinea pedis, sore subcutaneous ulcer pyogenic infections, bruise internal lesion caused by overexertion.It is because of it to select Chinese cassia tree Property acrid-sweet flavor, heat enters kidney, spleen, bladder warp, there is that complement is positive, warming spleen and stomach, removing internal cold, and the function of promoting blood circulation controls the Yang-function insufficiency of kidneyzang, limb Cold weak pulse, yang depletion collapse, abdominal pain diarrhea, cold hernia run quickly globefish, waist and knee crymodynia, Jing Bi Disorder lumps in the abdomen, cloudy subcutaneous ulcer, streamer, and empty sun are floating more, upper heat It is lower cold.It is arduous because of its nature and flavor to select lepidium seed, trembles with fear, enters lung, bladder warp, there is the function of lower gas row water, controls lung and stops up asthma suddenly, phlegm Drink cough, oedema turgor.It is to enter lung, large intestine channel because its nature and flavor is acrid in flavour and warm in nature, there is lower gas, dissolving phlegm, moistening lung, wide intestines to select perilla seed Function, it is inverse to control cough, phlegm asthma, the stagnation of the circulation of vital energy, constipation.It selects waxgourd peel and is because its nature and flavor is sweet, it is cool, enter spleen, lung two passes through, advantageous water disappears The function of kind, harnesses the river swollen, diarrhea, carbuncle swells.It is to tremble with fear because its is bitter in taste, enter wing thorax, spleen, kidney channel, have row water, rush down to select the root of fangji The function of damp-heat in lower-JIAO, swollen tympanites of harnessing the river, hygropyretic beriberi, brothers' contraction pain, tinea scabies sore swells.It is because its nature and flavor is pungent to select evodia rutaecarpa Hardship, temperature is toxic, enters liver, stomach, there is middle benefit gas, relieves pain, qi-regulating, the function of eliminating dampness, controls inverse acid regurgitation of vomitting, jueyin headache, and the cold syndrome in infant is spat It rushes down, abdominal distention, tinea pedis, hernia, aphthous ulcer, dentalgia, eczema, impetigo.Select Fructus Forsythiae be because its is bitter in taste, it is cool, enter The heart, liver, gallbladder channel have heat-clearing, and removing toxic substances, dissipating bind, the function of detumescence controls warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching It closes.It is to enter spleen, stomach, large intestine channel because its is bitter in taste acrid in flavour and warm in nature to select Cortex Magnoliae Officinalis, there is a middle benefit gas, lower gas, eliminating dampness, and the function of dissolving phlegm is controlled Chest and abdomen feeling of fullness distending pain, gastric disorder causing nausea, vomiting, place food do not disappear, sputum cough, cold-dampness rush down dysentery.Select rhizoma imperatae be because its nature and flavor it is sweet, It is cold, enter lung, stomach, small intestinl channel, there is cool blood, stops blooding, heat-clearing, the function of diuresis controls pyreticosis polydipsia, spits blood, bleeding from five sense organs or subcutaneous tissue, and lung heat asthma is anxious, Stomach energy hiccup, gonorrhoea, difficult urination, oedema, jaundice.Select coix seed be because of its property slightly sweet flavor, it is cool, enter spleen, lung, kidney channel, There is an invigorating the spleen, tonifying lung, heat-clearing, the function of dampness removing controls diarrhea, arthritis with fixed pain caused by dampness, muscle arteries and veins contraction, joint stuffiness, oedema, tinea pedis, consumptive lung disease, lung Carbuncle, acute appendicitis, stranguria with turbid discharge, leukorrhea.
Specific implementation mode
The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy All tools have a better effect in amount range:
5-15 grams of wrinkled giant hyssop, 5-15 grams of the tuber of pinellia, 5-15 grams of Cortex Magnoliae Officinalis, 5-15 grams of Fructus Aurantii, 5-15 grams of Amomum cardamomum, 5-15 grams of campanulaceae, almond 5-15 grams, 10-20 grams of Chinese Drug Gualouzi, 5-15 grams of Radix Angelicae Sinensis, 5-15 grams of brush-cherry seed, 5-15 grams of peach kernel, 5-15 grams of the fruit of Chinese wolfberry, Chinese ephedra 10- 20 grams, 10-20 grams of dried orange peel, 10-20 grams of the shell of areca nut, 10-20 grams of rhizoma alismatis, 15-25 grams of Rhizoma Atractylodis Macrocephalae, 10-20 grams of Poria cocos, cassia twig 10-20 Gram, 10-20 grams of umbellate pore furgus, 10-20 grams of cortex acanthopanacis, 5-15 grams of Chinese cassia tree, 10-20 grams of lepidium seed, 5-15 grams of perilla seed, waxgourd peel 10- 20 grams, 5-15 grams of the root of fangji, 4-8 grams of evodia rutaecarpa, 5-15 grams of Fructus Forsythiae, 4-8 grams of Cortex Magnoliae Officinalis, 10-14 grams of rhizoma imperatae, 15-25 grams of coix seed.
Preferably:
10 grams of wrinkled giant hyssop, 10 grams of the tuber of pinellia, 10 grams of Cortex Magnoliae Officinalis, 10 grams of Fructus Aurantii, 10 grams of Amomum cardamomum, 10 grams of campanulaceae, 10 grams of almond, Chinese Drug Gualouzi 15 Gram, 10 grams of Radix Angelicae Sinensis, 10 grams of brush-cherry seed, 10 grams of peach kernel, 10 grams of the fruit of Chinese wolfberry, 15 grams of Chinese ephedra, 15 grams of dried orange peel, 15 grams of the shell of areca nut, rhizoma alismatis 15 grams, 20 grams of Rhizoma Atractylodis Macrocephalae, 15 grams of Poria cocos, 15 grams of cassia twig, 15 grams of umbellate pore furgus, 15 grams of cortex acanthopanacis, 10 grams of Chinese cassia tree, 15 grams of lepidium seed, purple perilla 10 grams of son, 15 grams of waxgourd peel, 10 grams of the root of fangji, 6 grams of evodia rutaecarpa, 10 grams of Fructus Forsythiae, 6 grams of Cortex Magnoliae Officinalis, 12 grams of rhizoma imperatae, 20 grams of coix seed.
The preparation method of drug of the present invention is as follows
One, it stocks up
1, wrinkled giant hyssop:Pick impurity, remove undesirable root and old stem, first leaf is taken and is separately put, stem is moisturized with water, and segment is dried, then with Leaf and even;
2, the tuber of pinellia:Impurity is picked, grey bits are weeded out;
3, Cortex Magnoliae Officinalis:It is soaked in water and pulls out, tertia is scraped off after moisturizing, clean, chopping is dried;
4, Fructus Aurantii:Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and it is degree that can pinch doubling with hand, and slice dries;
5, Amomum cardamomum:Net impurity is picked, scurf is weeded out, is smashed, or peels off shell, kernel-taking smashes use;
6, campanulaceae:Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing;
7, almond:Net impurity is picked, sets in boiling water and slightly boils, is pulled out when crust microcreping, is soaked in cold water, is sloughed kind of a skin, dry, winnow with a dustpan Only;
8, Chinese Drug Gualouzi:Crude drug is taken, shrivelled seed, impurity are removed, the used time smashs to pieces;
9, Radix Angelicae Sinensis:Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries;
10, brush-cherry seed:Spare is weeded out, is washed in a pan only, is picked net impurity and broken shell, dry, the used time smashs to pieces;
11, peach kernel:Hard shell impurity is removed, sets in boiling water pot and boils to crust microcreping, pull out, is immersed in cold water, kind of a skin is removed in stranding, shines It is dry, it winnows with a dustpan net;
12, the fruit of Chinese wolfberry:It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit;
13, Chinese ephedra:Impurity is picked, most woody stems and undesirable root is removed, is eluted with water, segment after micro- profit is drying to obtain;
14, dried orange peel:Crude drug is taken, impurity and the pericarp of blackening are removed, wash quickly is net, softens, chopping, dry or low temperature dry, Weed out grey bits;
15, the shell of areca nut:Pick net impurity, rolloff makes soft, beats, weeds out spare;
16, rhizoma alismatis:Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, bored profit to uniform humidity inside and outside, Slice, is dried;
17, Rhizoma Atractylodis Macrocephalae:Net impurity is picked, is soaked in water, is pulled out after bubble, is moisturized, is sliced, dries;
18, Poria cocos:It is soaked in water, cleans and pull out, after bored, slice dries;
19, cassia twig:It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit;
20, umbellate pore furgus:Silt particle is cleaned, slice is softened, dries;
21, cortex acanthopanacis:Net impurity is picked, is eluted with water, after slightly moistening, is sliced, it is dry;
22, Chinese cassia tree:Net impurity is picked, tertia is scraped off, the used time smashes, or scrapes off tertia, infiltrates a moment with warm water, slice dries;
23, lepidium seed:Net impurity is picked, grey bits are weeded out;
24, perilla seed:Dedusting of winnowing with a dustpan is considered to be worth doing, is cleaned, is dried;
25, waxgourd peel:Crude drug is taken, removes impurity and rotten person of going rotten, wash quickly is net, stripping and slicing or silk, dry, weeds out clast;
26, the root of fangji:Active compound is eluted with water, and pulls out and moisturizes, and slice dries;
27, evodia rutaecarpa:Crude drug is taken, carpopodium, branch and impurity is removed, weeds out clast;
28, Fructus Forsythiae:Net impurity is picked, is rubbed open, discarding stalk is removed;
29, Cortex Magnoliae Officinalis:It is soaked in water and pulls out, tertia is scraped off after moisturizing, clean, chopping is dried;
30, rhizoma imperatae:Net impurity is picked, is cleaned, micro- profit, segment is dried, net clast of winnowing with a dustpan;
31, coix seed:Crude drug is taken, residual leather shell, impurity are removed.
Two, it prepares
1, by the wrinkled giant hyssop of the weight, the tuber of pinellia, Cortex Magnoliae Officinalis, Fructus Aurantii, Amomum cardamomum, campanulaceae, almond, Chinese Drug Gualouzi, Radix Angelicae Sinensis, brush-cherry seed, peach Benevolence, the fruit of Chinese wolfberry, Chinese ephedra, dried orange peel, the shell of areca nut, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig, umbellate pore furgus, cortex acanthopanacis, Chinese cassia tree, lepidium seed, purple perilla Son, waxgourd peel, the root of fangji, evodia rutaecarpa, Fructus Forsythiae, Cortex Magnoliae Officinalis, rhizoma imperatae, coix seed are put into decocting container, are added 8 times of amounts of water, are impregnated 100 After minute, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into In container;
2, the dregs of a decoction of filtering are added into 6 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor;
3, it decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.
There is brush-cherry seed in prescription moisturizes, laxation, lower gas, and the function of Li Shui is monarch drug in a prescription;The shell of areca nut have lower gas it is wide in, row water Function;The advantageous water of rhizoma alismatis, excreting dampness, the function of expelling the heat-evil, the two are ministerial drug, and three taste medicines play moisturize laxation jointly, lower gas Li Shui, under During gas is wide, the effect of clearing damp and promoting diuresis, treatment oedema effect is comprehensive, and following gas Li Shui can be controlled during lower gas is wide based on clearing damp and promoting diuresis This, Rhizoma Atractylodis Macrocephalae has tonifying spleen benefit stomach, and function of the eliminating dampness in is adjutant, and Poria cocos has eliminating dampness and diuresis, beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative To make medicine, all medicines are to take stopgap measures with being left.
Drug of the present invention have lower gas Li Shui, during lower gas is wide, clearing damp and promoting diuresis, tonifying spleen benefit stomach, eliminating dampness and in function, be used for Treat oedema, short treating period, quick, non-relapse after healing.
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.
The animal toxicity test of [test example 1] drug of the present invention is reported:
Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] drug of the present invention
1, general information
Accept oedema out-patient totally 35 for medical treatment.
2, diagnostic criteria
Classical symptom is locality or anasarca, often has dropsy of serous cavity simultaneously when anasarca, such as ascites, thoracic cavity Hydrops and pericardial effusion.
3, therapy
Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, and 7 days as a course for the treatment of, continuous to take With 3 courses for the treatment of.
4, efficacy assessment standard
It is effective:Edematous condition disappears, and constitution restores normal, recovery from illness;
It improves:Edematous condition is clearly better, and ascites and pleural effusion are reduced, and gradually restores normal;
In vain:Improvement standard person is not achieved.
5, treatment results(It see the table below)
In above-mentioned treatment, with drug therapy edematous patient 35 of the present invention, as a result effective 30, obvious effective rate 85.7% improves 3, improvement rate 8.6%, invalid 2, total effective rate 94.3%.

Claims (3)

1. a kind of drug for treating oedema, it is characterised in that:It is made of the bulk pharmaceutical chemicals in following weight range:
5-15 grams of wrinkled giant hyssop, 5-15 grams of the tuber of pinellia, 5-15 grams of Cortex Magnoliae Officinalis, 5-15 grams of Fructus Aurantii, 5-15 grams of Amomum cardamomum, 5-15 grams of campanulaceae, almond 5-15 grams, 10-20 grams of Chinese Drug Gualouzi, 5-15 grams of Radix Angelicae Sinensis, 5-15 grams of brush-cherry seed, 5-15 grams of peach kernel, 5-15 grams of the fruit of Chinese wolfberry, Chinese ephedra 10- 20 grams, 10-20 grams of dried orange peel, 10-20 grams of the shell of areca nut, 10-20 grams of rhizoma alismatis, 15-25 grams of Rhizoma Atractylodis Macrocephalae, 10-20 grams of Poria cocos, cassia twig 10-20 Gram, 10-20 grams of umbellate pore furgus, 10-20 grams of cortex acanthopanacis, 5-15 grams of Chinese cassia tree, 10-20 grams of lepidium seed, 5-15 grams of perilla seed, waxgourd peel 10- 20 grams, 5-15 grams of the root of fangji, 4-8 grams of evodia rutaecarpa, 5-15 grams of Fructus Forsythiae, 4-8 grams of Cortex Magnoliae Officinalis, 10-14 grams of rhizoma imperatae, 15-25 grams of coix seed.
2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is:
10 grams of wrinkled giant hyssop, 10 grams of the tuber of pinellia, 10 grams of Cortex Magnoliae Officinalis, 10 grams of Fructus Aurantii, 10 grams of Amomum cardamomum, 10 grams of campanulaceae, 10 grams of almond, Chinese Drug Gualouzi 15 Gram, 10 grams of Radix Angelicae Sinensis, 10 grams of brush-cherry seed, 10 grams of peach kernel, 10 grams of the fruit of Chinese wolfberry, 15 grams of Chinese ephedra, 15 grams of dried orange peel, 15 grams of the shell of areca nut, rhizoma alismatis 15 grams, 20 grams of Rhizoma Atractylodis Macrocephalae, 15 grams of Poria cocos, 15 grams of cassia twig, 15 grams of umbellate pore furgus, 15 grams of cortex acanthopanacis, 10 grams of Chinese cassia tree, 15 grams of lepidium seed, purple perilla 10 grams of son, 15 grams of waxgourd peel, 10 grams of the root of fangji, 6 grams of evodia rutaecarpa, 10 grams of Fructus Forsythiae, 6 grams of Cortex Magnoliae Officinalis, 12 grams of rhizoma imperatae, 20 grams of coix seed.
3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps:
(One)Stock
(1)Wrinkled giant hyssop:Impurity is picked, undesirable root and old stem is removed, first leaf is taken and is separately put, stem is moisturized with water, and segment is dried, then With leaf and even;
(2)The tuber of pinellia:Impurity is picked, grey bits are weeded out;
(3)Cortex Magnoliae Officinalis:It is soaked in water and pulls out, tertia is scraped off after moisturizing, clean, chopping is dried;
(4)Fructus Aurantii:Flesh, core are removed, edulcoration is slightly soaked, pulled out, softens, and it is degree that can pinch doubling with hand, and slice dries;
(5)Amomum cardamomum:Net impurity is picked, scurf is weeded out, is smashed, or peels off shell, kernel-taking smashes use;
(6)Campanulaceae:Net impurity is picked, removing LU is removed, cleans and pulls out, be sliced, dry after moisturizing;
(7)Almond:Net impurity is picked, sets in boiling water and slightly boils, is pulled out when crust microcreping, is soaked in cold water, is sloughed kind of a skin, dry, winnow with a dustpan Only;
(8)Chinese Drug Gualouzi:Crude drug is taken, shrivelled seed, impurity are removed, the used time smashs to pieces;
(9)Radix Angelicae Sinensis:Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries;
(10)Brush-cherry seed:Spare is weeded out, is washed in a pan only, is picked net impurity and broken shell, dry, the used time smashs to pieces;
(11)Peach kernel:Hard shell impurity is removed, sets in boiling water pot and boils to crust microcreping, pull out, is immersed in cold water, kind of a skin is removed in stranding, shines It is dry, it winnows with a dustpan net;
(12)The fruit of Chinese wolfberry:It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit;
(13)Chinese ephedra:Impurity is picked, most woody stems and undesirable root is removed, is eluted with water, segment after micro- profit is drying to obtain;
(14)Dried orange peel:Crude drug is taken, impurity and the pericarp of blackening are removed, wash quickly is net, softens, chopping, dry or low temperature dry, Weed out grey bits;
(15)The shell of areca nut:Pick net impurity, rolloff makes soft, beats, weeds out spare;
(16)Rhizoma alismatis:Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, bored profit to uniform humidity inside and outside, Slice, is dried;
(17)Rhizoma Atractylodis Macrocephalae:Net impurity is picked, is soaked in water, is pulled out after bubble, is moisturized, is sliced, dries;
(18)Poria cocos:It is soaked in water, cleans and pull out, after bored, slice dries;
(19)Cassia twig:It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit;
(20)Umbellate pore furgus:Silt particle is cleaned, slice is softened, dries;
(21)Cortex acanthopanacis:Net impurity is picked, is eluted with water, after slightly moistening, is sliced, it is dry;
(22)Chinese cassia tree:Net impurity is picked, tertia is scraped off, the used time smashes, or scrapes off tertia, infiltrates a moment with warm water, slice dries in the air It is dry;
(23)Lepidium seed:Net impurity is picked, grey bits are weeded out;
(24)Perilla seed:Dedusting of winnowing with a dustpan is considered to be worth doing, is cleaned, is dried;
(25)Waxgourd peel:Crude drug is taken, removes impurity and rotten person of going rotten, wash quickly is net, stripping and slicing or silk, dry, weeds out clast;
(26)The root of fangji:Active compound is eluted with water, and pulls out and moisturizes, and slice dries;
(27)Evodia rutaecarpa:Crude drug is taken, carpopodium, branch and impurity is removed, weeds out clast;
(28)Fructus Forsythiae:Net impurity is picked, is rubbed open, discarding stalk is removed;
(29)Cortex Magnoliae Officinalis:It is soaked in water and pulls out, tertia is scraped off after moisturizing, clean, chopping is dried;
(30)Rhizoma imperatae:Net impurity is picked, is cleaned, micro- profit, segment is dried, net clast of winnowing with a dustpan;
(31)Coix seed:Crude drug is taken, residual leather shell, impurity are removed;
(Two)It prepares
(1)By the wrinkled giant hyssop of the weight, the tuber of pinellia, Cortex Magnoliae Officinalis, Fructus Aurantii, Amomum cardamomum, campanulaceae, almond, Chinese Drug Gualouzi, Radix Angelicae Sinensis, brush-cherry seed, peach Benevolence, the fruit of Chinese wolfberry, Chinese ephedra, dried orange peel, the shell of areca nut, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig, umbellate pore furgus, cortex acanthopanacis, Chinese cassia tree, lepidium seed, purple perilla Son, waxgourd peel, the root of fangji, evodia rutaecarpa, Fructus Forsythiae, Cortex Magnoliae Officinalis, rhizoma imperatae, coix seed are put into decocting container, are added 8 times of amounts of water, are impregnated 100 After minute, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into In container;
(2)The dregs of a decoction of filtering are added into 6 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor;
(3)It decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.
CN201810405620.1A 2018-04-29 2018-04-29 A kind of drug and preparation method thereof for treating oedema Withdrawn CN108420984A (en)

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