CN108378243A - A kind of feed for sow additive and its application - Google Patents

A kind of feed for sow additive and its application Download PDF

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Publication number
CN108378243A
CN108378243A CN201810472912.7A CN201810472912A CN108378243A CN 108378243 A CN108378243 A CN 108378243A CN 201810472912 A CN201810472912 A CN 201810472912A CN 108378243 A CN108378243 A CN 108378243A
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China
Prior art keywords
sow
feed
fructose
diphosphate
additive
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CN201810472912.7A
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Chinese (zh)
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CN108378243B (en
Inventor
陈晓春
张磊
汤亦文
周昌祝
蔡家栋
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NANJING BIO TOGETHER CO Ltd
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NANJING BIO TOGETHER CO Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/153Nucleic acids; Hydrolysis products or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/26Compounds containing phosphorus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of feed for sow additives, it includes 10~90% mixture of ribonucleotides and the 1 of 10~90%, and 6 diphosphofructose salt, the mixture of ribonucleotides includes nucleotide, oligonucleotides, yeast dextran and Yeast protein.Compared with prior art, the present invention can promote sow to ovulate, and improve live embryo number, and then improve nest and produce quantity;Meanwhile the present invention can dramatically increase sow immunity, improve piglet birth weight and number of weaned.In addition, the invention belongs to biologies to manufacture product, green pollution-free.

Description

A kind of feed for sow additive and its application
Technical field
The invention belongs to feed additive fields, and in particular to a kind of feed for sow additive and its application.
Background technology
With the fast development of intensive pig production industry, sow production develops mostly important link as pig breeding industry.Cause How this, improve pregnant sow breeding production performance and its health status of farrowed pig, become numerous raisers and be concerned about the most The problem of.
Currently, the feed addictive for improving the production performance of pregnant sow is mainly Chinese herbal medicine compound additive, although effect Fruit is more apparent.But there are problems for Chinese medicine feed addictive, and quality of medicinal material is irregular first and active ingredient is difficult to Control, and production cost is higher.As the developed countries such as America and Europe gradually ban antibiotic and the country to livestock products healthy aquaculture Active demand therefore seek a kind of functional feedstuff additive, first half period of gestation promote sow ovulation, improve live embryo number, Later stage improves sow immunity, and then the breeding production performance for improving sow becomes the hot spot studied both at home and abroad.
For the present invention by mixture of ribonucleotides, the mixture of fructose 1,6-diphosphate salt combines that prepare can according to a certain ratio Increase sow nest and produce quantity, improve immunity function, and then improves the functional feedstuff additive of pregnant sow breeding production performance.
The sow general level of the health and production capacity, the Sun Xuemei of Hinapharm Pharmaceutical Co., Ltd. can be improved in nucleotide Deng feeding sow, but its nest yield and the increased unobvious of weight of weaning litter using yeast cake nucleotide as feed addictive. FDP can penetrate cell membrane and enter into the cell, participate in adjusting intracellular a variety of metabolic processes from cellular and molecular level, so as to improve The energetic supersession of cell, increase can utilize, and improve immunity of organisms.Although patent CN01904856A has studied 1,6- diphosphonic acid Effect of the fruit carbohydrates and their derivative in animal health, but it is not applied to sow experiment.
Invention content
The technical problem to be solved in the present invention is to provide a kind of feed for sow additives extremely to apply, to solve existing skill The problems such as ineffective existing for art.
In order to solve the above technical problems, the technical solution adopted by the present invention is as follows:
A kind of feed for sow additive, it includes the component of following mass percent:
Mixture of ribonucleotides 10~90%;
Fructose 1,6-diphosphate salt 10~90%;
Wherein, the mixture of ribonucleotides includes nucleotide, oligonucleotides, yeast dextran and Yeast protein.
Wherein, the component of preferably following mass percent:
Mixture of ribonucleotides 40~60%;
Fructose 1,6-diphosphate salt 40~60%.
Further, the component of preferably following mass percent:
Mixture of ribonucleotides 50%;
Fructose 1,6-diphosphate salt 50%.
Wherein, the fructose 1,6-diphosphate salt include fructose 1,6-diphosphate sodium salt, fructose 1,6-diphosphate magnesium salts, Any one or the combination of several of them in fructose 1,6-diphosphate calcium salt and fructose 1,6-diphosphate zinc salt.
Wherein, the fructose 1,6-diphosphate salt includes the component of following mass percent:
Further, the component of preferably following mass percent:
Wherein, the mixture of ribonucleotides includes the component of following mass percent:
Wherein, the component of preferably following mass percent:
Further, the component of preferably following mass percent:
Application of the above-mentioned feed for sow additive in sow feed is also within protection scope of the present invention.
Wherein, application process is that the feed for sow additive is added in sow basal feed.
Wherein, the additive amount of the feed for sow additive is 0.01~5wt ‰, and preferably 0.1~1wt ‰ adds Dosage is the mass ratio of the feed for sow additive and sow basal feed.
Wherein, the feed for sow additive is added to the time in sow basal feed as 7 days sow prefecundations First 20 days are produced to weaned piglet to after fertilization 20 days and sow.
Advantageous effect:
Compared with prior art, the present invention has following advantage:
(1) present invention can promote sow to ovulate, and improve live embryo number, and then improve nest and produce quantity;
(2) present invention can dramatically increase sow immunity, improve piglet birth weight and number of weaned;
(3) the invention belongs to biologies to manufacture product, green pollution-free.
Specific implementation mode
According to following embodiments, the present invention may be better understood.However, as it will be easily appreciated by one skilled in the art that real It applies content described in example and is merely to illustrate the present invention, without sheet described in detail in claims should will not be limited Invention.
In following embodiments, mixture of ribonucleotides and fructose 1,6-diphosphate salt are first sieved respectively with the sieve of 40 mesh, so It weighs two kinds of substances in proportion afterwards, mixes well up to the feed for sow additive of the present invention.
Embodiment 1:
Material and its mass percent:Mixture of ribonucleotides 20%, fructose 1,6-diphosphate salt 80%;The nucleotide Specifically proportioning is nucleotide 30%, oligonucleotides 65%, yeast dextran 2%, Yeast protein 3% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 30%, fructose 1,6-diphosphate magnesium salts 30%, 1,6- diphosphonic acid fruit Sugar calcium salt 20%, fructose 1,6-diphosphate zinc salt 20%.
Embodiment 2:
Material and its mass percent:Mixture of ribonucleotides 30%, fructose 1,6-diphosphate salt 70%;The nucleotide Specifically proportioning is nucleotide 65%, oligonucleotides 30%, yeast dextran 3%, Yeast protein 2% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 25%, fructose 1,6-diphosphate magnesium salts 25%, 1,6- diphosphonic acid fruit Sugar calcium salt 25%, fructose 1,6-diphosphate zinc salt 25%.
Embodiment 3:
Material and its mass percent:Mixture of ribonucleotides 50%, fructose 1,6-diphosphate salt 50%;The nucleotide Specifically proportioning is nucleotide 45%, oligonucleotides 50%, yeast dextran 2%, Yeast protein 3% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 20%, fructose 1,6-diphosphate magnesium salts 30%, 1,6- diphosphonic acid fruit Sugar calcium salt 25%, fructose 1,6-diphosphate zinc salt 25%.
Embodiment 4:
Material and its mass percent:Mixture of ribonucleotides 50%, fructose 1,6-diphosphate salt 50%;The nucleotide Specifically proportioning is nucleotide 25%, oligonucleotides 68%, yeast dextran 3%, Yeast protein 4% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 20%, fructose 1,6-diphosphate magnesium salts 20%, 1,6- diphosphonic acid fruit Sugar calcium salt 30%, fructose 1,6-diphosphate zinc salt 30%.
Embodiment 5:
Material and its mass percent:Mixture of ribonucleotides 70%, fructose 1,6-diphosphate salt 30%;The nucleotide Specifically proportioning is nucleotide 30%, oligonucleotides 62%, yeast dextran 4%, Yeast protein 4% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 25%, fructose 1,6-diphosphate magnesium salts 20%, 1,6- diphosphonic acid fruit Sugar calcium salt 25%, fructose 1,6-diphosphate zinc salt 20%.
Embodiment 6:
Material and its mass percent:Mixture of ribonucleotides 80%, fructose 1,6-diphosphate salt 20%;The nucleotide Specifically proportioning is nucleotide 50%, oligonucleotides 48%, yeast dextran 1%, Yeast protein 1% to mixture;Described 1,6- Diphosphofructose salt proportioning is fructose 1,6-diphosphate sodium salt 20%, fructose 1,6-diphosphate magnesium salts 25%, 1,6- diphosphonic acid fruit Sugar calcium salt 35%, fructose 1,6-diphosphate zinc salt 20%.
Embodiment 7:
Selection health, body condition are good to use sow 112 through production kind, is grouped as 7 groups at random, mean gestational age is made to be distributed one It causes, every group of 16 sows.7 days to latter 20 days before experimental group insemination of sows, and production is fed to weaned piglet and is tested for first 20 days Formula.
7 groups of experiments are respectively:
Experimental group 1:Additive described in embodiment 1 is added in sow basal feed, additive amount is 2 ‰;
Experimental group 2:Additive described in embodiment 2 is added in sow basal feed, additive amount is 5 ‰;
Experimental group 3:Additive described in embodiment 3 is added in sow basal feed, additive amount is 0.5 ‰;
Experimental group 4:Additive described in embodiment 4 is added in sow basal feed, additive amount is 0.2 ‰;
Experimental group 5:Additive described in embodiment 5 is added in sow basal feed, additive amount is 0.05 ‰;
Experimental group 6:Additive described in embodiment 6 is added in sow basal feed, additive amount is 0.01 ‰;
Experimental group 7:Control group;
Wherein, the formula of sow basal feed is as shown in table 1, daily respectively 8:00、14:00 and 20:00 point 3 times it is enough Feeding.
Raw material forms Mass percent (%)
Corn 65.2
Wheat bran 5.6
Soybean skin 2.8
Soybean oil 1.4
Dregs of beans 18.4
Rapeseed dregs 2.1
Compound premix 4.5
It is total 100
Pregnant sow free water, and the litter size of record sow, young Birth weight and 24 age in days weaning weights respectively, experiment knot Fruit is as shown in table 2.
1 litter size of table, young Birth weight, average mortality and weaning weight on the 24th
According to upper table:Feed addictive component in Examples 1 to 6 substantially increases the growth rate of sucking pig, drop The low death rate of sucking pig, reduces the feeding cost and economic loss of people.
Embodiment 8:
Using the product of the present invention in embodiment 3 as feed addictive, parallel laboratory test is done on the basis of above-mentioned experimental group 3, Wherein, additive amount is respectively 0.02 ‰, 0.5 ‰ and 2 ‰, remaining condition is identical.Experimental result is as shown in table 2, it can be seen that when Additive amount is 0.5 ‰, and effect is best.
Table 2
Adding proportion Litter size (head) Young Birth weight (kg) Average mortality (%) Weaning weight (kg) on the 24th
0.02‰ 10.2 0.68 2.4 6.9
0.5‰ 10.5 0.74 0 7.6
2‰ 10.3 0.70 1.8 7.1

Claims (8)

1. a kind of feed for sow additive, which is characterized in that it includes the component of following mass percent:
Mixture of ribonucleotides 10~90%;
Fructose 1,6-diphosphate salt 10~90%;
Wherein, the mixture of ribonucleotides includes nucleotide, oligonucleotides, yeast dextran and Yeast protein.
2. feed for sow additive according to claim 1, which is characterized in that the fructose 1,6-diphosphate salt packet Include fructose 1,6-diphosphate sodium salt, fructose 1,6-diphosphate magnesium salts, fructose 1,6-diphosphate calcium salt and fructose 1,6-diphosphate zinc Any one or the combination of several of them in salt.
3. feed for sow additive according to claim 1, which is characterized in that the fructose 1,6-diphosphate salt packet Include the component of following mass percent:
4. feed for sow additive according to claim 1, which is characterized in that the mixture of ribonucleotides includes such as The component of lower mass percent:
5. application of the feed for sow additive described in claim 1 in sow feed.
6. application according to claim 5, which is characterized in that application process is, by the feed for sow additive It is added in sow basal feed.
7. application according to claim 6, which is characterized in that the additive amount of the feed for sow additive is 0.01 ~5wt ‰.
8. application according to claim 6, which is characterized in that the feed for sow additive is added to sow basis Time in feed, which is 7 days sow prefecundations, produces first 20 days to weaned piglet to after fertilization 20 days and sow.
CN201810472912.7A 2018-05-17 2018-05-17 Feed additive for sows and application thereof Active CN108378243B (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004313178A (en) * 2003-03-31 2004-11-11 Kohjin Co Ltd Method for increasing 5'-nucleotide content in mother's milk of mother sow, additive to feed for mother sow and feed for mother sow
CN1864516A (en) * 2005-05-20 2006-11-22 万代生物技术(深圳)有限公司 A method for preparing feedstuff addictive from yeast
CN101480220A (en) * 2008-11-07 2009-07-15 江苏省苏微微生物研究有限公司 Method for preparing mixed type nucleotide feed addictive from yeast cell and application
CN101904856A (en) * 2010-08-06 2010-12-08 南京南农高科兽药研究所有限公司 Application of 1,6-diphosphofructose and derivative thereof in preparing animal medical health care products
CN103589641A (en) * 2012-08-17 2014-02-19 广州市纽溢乐商贸有限公司 Three-step enzymatic hydrolysis method used for producing forage saccharomyces cerevisiae cells with broken-down walls
CN104855733A (en) * 2015-06-10 2015-08-26 南京同凯兆业生物技术有限责任公司 Application of yeast containing active polysaccharides and nucleotides in dairy cow feed
CN107712345A (en) * 2017-10-17 2018-02-23 南京工业大学 Nucleotide mixture crystal powder and preparation method thereof

Patent Citations (7)

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Publication number Priority date Publication date Assignee Title
JP2004313178A (en) * 2003-03-31 2004-11-11 Kohjin Co Ltd Method for increasing 5'-nucleotide content in mother's milk of mother sow, additive to feed for mother sow and feed for mother sow
CN1864516A (en) * 2005-05-20 2006-11-22 万代生物技术(深圳)有限公司 A method for preparing feedstuff addictive from yeast
CN101480220A (en) * 2008-11-07 2009-07-15 江苏省苏微微生物研究有限公司 Method for preparing mixed type nucleotide feed addictive from yeast cell and application
CN101904856A (en) * 2010-08-06 2010-12-08 南京南农高科兽药研究所有限公司 Application of 1,6-diphosphofructose and derivative thereof in preparing animal medical health care products
CN103589641A (en) * 2012-08-17 2014-02-19 广州市纽溢乐商贸有限公司 Three-step enzymatic hydrolysis method used for producing forage saccharomyces cerevisiae cells with broken-down walls
CN104855733A (en) * 2015-06-10 2015-08-26 南京同凯兆业生物技术有限责任公司 Application of yeast containing active polysaccharides and nucleotides in dairy cow feed
CN107712345A (en) * 2017-10-17 2018-02-23 南京工业大学 Nucleotide mixture crystal powder and preparation method thereof

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