CN108137516A - 奥扎莫德的晶型、其制备方法及药物组合物 - Google Patents
奥扎莫德的晶型、其制备方法及药物组合物 Download PDFInfo
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- CN108137516A CN108137516A CN201680056784.7A CN201680056784A CN108137516A CN 108137516 A CN108137516 A CN 108137516A CN 201680056784 A CN201680056784 A CN 201680056784A CN 108137516 A CN108137516 A CN 108137516A
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Abstract
本发明涉及奥扎莫德的晶型,与已知的奥扎莫德相比,本发明的奥扎莫德晶型具有一种或多种改进的特性。本发明还涉及奥扎莫德晶型的制备方法、其药物组合物及其用于制备在医学上需要选择性鞘氨醇‑1‑磷酸酯受体的调节、活化、激动、抑制或拮抗的病症或不良状况的药物中的用途。
Description
PCT国内申请,说明书已公开。
Claims (18)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2016/099137 WO2018049632A1 (zh) | 2016-09-14 | 2016-09-14 | 奥扎莫德的晶型、其制备方法及药物组合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108137516A true CN108137516A (zh) | 2018-06-08 |
Family
ID=61618608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680056784.7A Pending CN108137516A (zh) | 2016-09-14 | 2016-09-14 | 奥扎莫德的晶型、其制备方法及药物组合物 |
Country Status (3)
Country | Link |
---|---|
US (1) | US11117875B2 (zh) |
CN (1) | CN108137516A (zh) |
WO (1) | WO2018049632A1 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017215617A1 (zh) | 2016-06-14 | 2017-12-21 | 苏州科睿思制药有限公司 | 奥扎莫德的晶型、其盐酸盐的晶型及其制备方法 |
WO2018033149A1 (zh) | 2016-08-19 | 2018-02-22 | 苏州科睿思制药有限公司 | 奥扎莫德的晶型及其制备方法 |
CN109640982A (zh) | 2016-09-14 | 2019-04-16 | 苏州科睿思制药有限公司 | 奥扎莫德盐酸盐的晶型及其制备方法 |
US20200087269A1 (en) * | 2017-05-22 | 2020-03-19 | Egis Gyogyszergyar Zrt. | Process for the production of ozanimod |
EP3677575A4 (en) | 2017-08-31 | 2020-07-15 | Crystal Pharmaceutical (Suzhou) Co., Ltd. | CRYSTALLINE FORM OF OZANIMODHYDROCHLORIDE AND PRODUCTION METHOD THEREFOR |
WO2019094409A1 (en) | 2017-11-07 | 2019-05-16 | Teva Pharmaceuticals International Gmbh | Salts and solid state forms of ozanimod |
EP4370117A1 (en) * | 2021-07-14 | 2024-05-22 | Zydus Lifesciences Limited | Pharmaceutical compositions of ozanimod |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102762100A (zh) * | 2009-11-13 | 2012-10-31 | 瑞塞普托斯公司 | 选择性的1-磷酸鞘氨醇受体调节剂及手性合成方法 |
WO2018033149A1 (zh) * | 2016-08-19 | 2018-02-22 | 苏州科睿思制药有限公司 | 奥扎莫德的晶型及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2010012461A (es) | 2008-05-14 | 2013-07-02 | Scripps Research Inst | Moduladores novedosos de receptores de fosfato de esfingosina. |
-
2016
- 2016-09-14 CN CN201680056784.7A patent/CN108137516A/zh active Pending
- 2016-09-14 US US16/333,287 patent/US11117875B2/en active Active
- 2016-09-14 WO PCT/CN2016/099137 patent/WO2018049632A1/zh active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102762100A (zh) * | 2009-11-13 | 2012-10-31 | 瑞塞普托斯公司 | 选择性的1-磷酸鞘氨醇受体调节剂及手性合成方法 |
WO2018033149A1 (zh) * | 2016-08-19 | 2018-02-22 | 苏州科睿思制药有限公司 | 奥扎莫德的晶型及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
US20190241530A1 (en) | 2019-08-08 |
US11117875B2 (en) | 2021-09-14 |
WO2018049632A1 (zh) | 2018-03-22 |
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