CN108066457A - A kind of Xuancheng's pawpaw wine of strong bone and its preparation method and application - Google Patents

A kind of Xuancheng's pawpaw wine of strong bone and its preparation method and application Download PDF

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Publication number
CN108066457A
CN108066457A CN201711425908.7A CN201711425908A CN108066457A CN 108066457 A CN108066457 A CN 108066457A CN 201711425908 A CN201711425908 A CN 201711425908A CN 108066457 A CN108066457 A CN 108066457A
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parts
xuancheng
pawpaw
strong bone
wine
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CN201711425908.7A
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Chinese (zh)
Inventor
陈家胜
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XUANCHENG HUAKE XUANMUGUA BIOTECHNOLOGY CO., LTD.
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Ningguo Balanced Health Management Co Ltd
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Priority to CN201711425908.7A priority Critical patent/CN108066457A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention provides a kind of Xuancheng's pawpaw wine of strong bone, it is prepared by the raw material of following parts by weight:20 30 parts of Xuancheng's pawpaw, 10 20 parts of pallas pit viper, 15 25 parts of fingered citron, 10 20 parts of Poria cocos, 10 14 parts of Chinese torreyanut, 15 25 parts of raspberry have strong bone effect, and disclose preparation method and purposes.

Description

A kind of Xuancheng's pawpaw wine of strong bone and its preparation method and application
Technical field
The present invention relates to health product technology fields, and in particular to Xuancheng's pawpaw wine of a kind of strong bone and preparation method thereof and should With.
Background technology
Osteoporosis, that is, osteoporosis, is one group of osteopathy caused by many reasons, and bone tissue has normal calcification, calcium salt With matrix in normal rates, the metabolic bone disease with the characteristics of the reduction of unit volume inner bone tissues amount becomes.In most osteoporosises In, caused by the reduction of bone tissue increases mainly due to bone absorption.By skeleton pain, be easy to fracture characterized by.People compel to be essential Want it is a kind of it is effective, oneself the health products of strong bone can be played by most people confirmation.
The content of the invention
Goal of the invention:To solve the above-mentioned problems, it is an object of the invention to provide a kind of strong bone Xuancheng's pawpaw wine and its Preparation method and application.
Technical solution:The purpose of the present invention is what is realized by following scheme:
A kind of Xuancheng's pawpaw wine of strong bone, it is prepared by the raw material of following parts by weight:20-30 parts of Xuancheng's pawpaw, pallas pit viper 10-20 parts, 15-25 parts of fingered citron, 10-20 parts of Poria cocos, 10-14 parts of Chinese torreyanut, 15-25 parts of raspberry.
The Xuancheng's pawpaw wine of the strong bone, it is prepared by the raw material of following parts by weight:25 parts of Xuancheng's pawpaw, pallas pit viper 15 Part, 20 parts of fingered citron, 15 parts of Poria cocos, 12 parts of Chinese torreyanut, 20 parts of raspberry.
The Xuancheng's pawpaw wine of the strong bone, the Xuancheng's pawpaw Wine-type are vina.
The Xuancheng's pawpaw wine of the strong bone, preparation method include the following steps:Take Xuancheng's pawpaw, pallas pit viper, fingered citron, Poria cocos, Chinese torreyanut, Raspberry raw material merge, when adding 30-50 degree soaking in Chinese liquor 24-48 small, filter to get.
Application of the Xuancheng's pawpaw wine of the strong bone in bone strengthening health-care product is prepared.
Xuancheng's pawpaw contains 19 kinds of amino acid, 18 kinds of mine trace elements and vitamin C, while also contains Saponin, flavones, malic acid, oleanolic acid, citric acid, citric acid, tartaric acid, ascorbic acid, fumaric acid, tannin etc., contain There are catalase, phenol oxidase, oxidizing ferment, especially rich in hepatocuprein (SOD) and oleanolic acid.Its SOD's contains Amount is impayable in all fruit in the world, and the content of one gram of Xuancheng's pawpaw fresh fruit SOD is up to 3227 international units.SOD is The core substance of modern beauty beauty treatment product can effectively eliminate superfluous free radical in vivo, promote body cell update.Olive Acid has broad-spectrum antibacterial action, has the effects that protect liver drop enzyme, promoting immunity, anti-inflammatory, reducing blood lipid blood glucose.Pallas pit viper, Chinese medicine name.For viper Section animal pallas pit viper Agkistrodon halys (Pallas) remove the entirety of internal organ.With wind-dispelling, dredging collateral, analgesic, the work(of removing toxic substances Effect.For arthralgia pain due to rheumatism, leprosy, scrofula, boil, mange, haemorrhoids, tumour.Fingered citron is used for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty Feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.Poria cocos is used for oedema oliguria, and phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea is confused and worried, Insomnia of palpitating with fear.Chinese torreyanut also known as Chinese torreya reality, Yushan fruit are the seed of taxaceae plant Chinese torreya.Chinese torreya also known as wild China fir, are aiphyllium, raw It is longer than hillside, wild or cultivation.Annual April blooms, October next year seed maturity, in drupe shape.It picks, removes after seed maturity Meat crust takes out seed, and drying can be used as medicine.Its is mild-natured, sweet in flavor, has effects that desinsection, disperse accumulation, moisturizes, for treating The diseases such as abdominal pain due to enterositosis, infantile malnutrition, cough caused by dryness, constipation, hemorrhoid.Raspberry, Chinese medicine name.For rosaceous plant rubus chingii Hu The dry fruit of Rubus chingii Hu.It is distributed in the ground such as Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Guangxi.Consolidate with kidney-nourishing Final minification is urinated, the effect of nourishing the liver to improve visual acuity.It is usually used in emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, mesh is secretly dim-sighted.
Advantageous effect:In terms of theory of traditional Chinese medical science, Xuancheng's pawpaw, pallas pit viper wind-dispelling in we, dredging collateral are relieved pain, detoxified as monarch drug in a prescription, Buddhist Hand, Poria cocos, Chinese torreyanut, raspberry supplementing the kidney to control the nocturnal contracting urine are ministerial drug, entirely can strong bone.
Specific embodiment
Form by the following examples is described in further detail the above of the present invention again, but should not be by this The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal Belong to the scope of the present invention.
Embodiment 1:Take 25 parts of 20 parts of Xuancheng's pawpaw, 20 parts of pallas pit viper, 15 parts of fingered citron, 20 parts of Poria cocos, 10 parts of Chinese torreyanut, raspberry originals Material merge, when adding 30 degree of soaking in Chinese liquor 48 small, filter to get.
Embodiment 2:Take 15 parts of 30 parts of Xuancheng's pawpaw, 10 parts of pallas pit viper, 25 parts of fingered citron, 10 parts of Poria cocos, 14 parts of Chinese torreyanut, raspberry originals Material merge, when adding 50 degree of soaking in Chinese liquor 24 small, filter to get.
Embodiment 3:Take 20 parts of 25 parts of Xuancheng's pawpaw, 15 parts of pallas pit viper, 20 parts of fingered citron, 15 parts of Poria cocos, 12 parts of Chinese torreyanut, raspberry originals Material merge, when adding 40 degree of soaking in Chinese liquor 36 small, filter to get.
Embodiment 4:The pharmacodynamic study of influence of the present invention to the bone density of experimental animal
Sample preparation:Test specimen is prepared by above-described embodiment 1, treasure strengthens SHENGU JIAONANG, and Shandong meeting elixir industry group is limited Company, lot number:20140611.Tretinoin piece, Shandong Liang Fu pharmaceutical Co. Ltds, lot number:140710
Animal:W istar rats, male, weight 180-240g, Shanghai Slac Experimental Animal Co., Ltd. provide.
The foundation of experiment packet and model rat with osteoporosis:Normal Wistar rats 30 is taken only to be randomly divided into 5 groups, take it In 6 be NS groups;It takes wherein 6 to be only used as model group, presses Tretinoin 70mg/kg gavages merely two weeks;Wherein 6 are taken to be only used as precious strengthen SHENGU JIAONANG control group;Remaining 12 rats are as the high low dose group of the present invention.As precious male SHENGU JIAONANG control group and this Invention high and low dose group gavages corresponding drug while gavaging Tretinoin by the dosage of 70mg/kg, gavage and withdraw dimension A after two weeks Acid continues two weeks and measures indices.Rat sacrificed by decapitation takes its femur to be taken the photograph by a group arrangement using X- line mammary gland video cameras Mating plate processed, with black and white densitometer in 5 positions are determined on the greater trochanter of femur, femoral head, neck of femur, intertrochanteric line and under intertrochanteric line Point measures and records bone density value.
Influence to rat bone density
Compared with model group, * 1P<0.01,*2P<0.05
The experimental results showed that the present invention compared with model group, has significant difference, it is close to illustrate that the present invention can improve bone Degree has strong bone effect, and effect is better than precious strong SHENGU JIAONANG.

Claims (5)

1. the Xuancheng's pawpaw wine of a kind of strong bone, which is characterized in that it is prepared by the raw material of following parts by weight:Xuancheng's pawpaw 20- 30 parts, 10-20 parts of pallas pit viper, 15-25 parts of fingered citron, 10-20 parts of Poria cocos, 10-14 parts of Chinese torreyanut, 15-25 parts of raspberry.
2. the Xuancheng's pawpaw wine of strong bone according to claim 1, which is characterized in that it is prepared by the raw material of following parts by weight It arrives:25 parts of Xuancheng's pawpaw, 15 parts of pallas pit viper, 20 parts of fingered citron, 15 parts of Poria cocos, 12 parts of Chinese torreyanut, 20 parts of raspberry.
3. the Xuancheng's pawpaw wine of strong bone according to claim 1, which is characterized in that the Xuancheng's pawpaw Wine-type is vina.
4. the Xuancheng's pawpaw wine of strong bone according to claim 1, which is characterized in that preparation method includes the following steps:Take Xuan Mu Melon, pallas pit viper, fingered citron, Poria cocos, Chinese torreyanut, raspberry raw material merge, when adding 30-50 degree soaking in Chinese liquor 24-48 small, filter to get.
5. application of the Xuancheng's pawpaw wine of strong bone in bone strengthening health-care product is prepared according to claim 1.
CN201711425908.7A 2017-12-26 2017-12-26 A kind of Xuancheng's pawpaw wine of strong bone and its preparation method and application Pending CN108066457A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110172380A (en) * 2019-05-17 2019-08-27 邱桂英 A kind of Chinese torreyanut grape wine and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102766561A (en) * 2012-08-20 2012-11-07 王杰 Tuckahoe psoralea nutrition wine and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102766561A (en) * 2012-08-20 2012-11-07 王杰 Tuckahoe psoralea nutrition wine and preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110172380A (en) * 2019-05-17 2019-08-27 邱桂英 A kind of Chinese torreyanut grape wine and preparation method thereof

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Effective date of registration: 20181205

Address after: 242000 Pioneering Road 23-3-2, Xuancheng Economic and Technological Development Zone, Xuancheng City, Anhui Province

Applicant after: XUANCHENG HUAKE XUANMUGUA BIOTECHNOLOGY CO., LTD.

Address before: 242000 Dangui Apartment, Renmin Road, Ningguo City, Xuancheng City, Anhui Province, 2 West 112 Storage, West 112, West 212

Applicant before: Ningguo balanced Health Management Company Limited

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20180525