CN108056466A - Red heart dragon fruit ferment and its application - Google Patents
Red heart dragon fruit ferment and its application Download PDFInfo
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- CN108056466A CN108056466A CN201810157336.7A CN201810157336A CN108056466A CN 108056466 A CN108056466 A CN 108056466A CN 201810157336 A CN201810157336 A CN 201810157336A CN 108056466 A CN108056466 A CN 108056466A
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- dragon fruit
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
A kind of red heart dragon fruit ferment and its application, are related to functional food health product technology field.The red heart dragon fruit ferment of the embodiment of the present invention is mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide by weight 10：1~6 is allocated to obtain, and the red heart dragon fruit ferment is in good taste, is easily absorbed by the body, and effect is comprehensive, and economic value is high.The application of the red heart dragon fruit ferment of the embodiment of the present invention is to can be made into the basic metabolism of raising human body, the gene expression of regulation and control gastrointestinal mucosa cells, repair gastrointestinal mucosa, auxiliary treatment gastric ulcer, adjusting intestinal flora environment, it relaxes bowel, prevents the health products of colorectal cancer health-care efficacy.
Description
Technical field
The present invention relates to functional food health product technology field, and more particularly to a kind of red heart dragon fruit ferment and its should
With.
Background technology
Galactooligosaccharide (GOS) is a kind of functional oligose with natural attribute, and molecular structure is usually half
1~7 galactosyl is connected on lactose or glucose molecule, sugariness is the 20%~40% of sucrose, and dissolubility is good, and heat is low,
With stronger acid resistance, heat resistance, it is suitable in the relatively low food of pH.Galactooligosaccharide (GOS) is the human body enteral youth
Bifidobacterium, bifidobacterium bifidum, bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, lactobacillus acidophilus, cheese breast bar
The fabulous nutrient source of the 8 big beneficial bacterium such as bacterium, Lactobacillus salivarius and effective proliferation factor, can improve human body intestinal canal Tiny ecosystem ring
Border, research it has also been found that galactooligosaccharide can promote intestinal mucosa reparation, promote body to the absorptions of minerals, adjust lipid metabolism,
Enhance immunity of organisms, reduce cancer morbidity, particularly obtained in the application in enterogastric diseases field it is many into
Effect[1][2].In modern society's inferior health, hypoimmunity, functions of intestines and stomach be disorderly, under overall background of basic metabolism dysfunction, low
Poly- galactolipin has been widely used in infant food, candy, fermentation type milk product, beverage and clinic because its multiple beneficial acts on
In nutraceutical, drinks, bakery product, frozen dessert.
Short chain fatty acids (SCFA), also referred to as volatile fatty acid, according in carbon number carbon atom number, carbon atom
Number is known as short chain fatty acids for 1~6 organic aliphatic acid.The supplement of short chain fatty acids is from extraneous intake and enteron aisle in human body
Interior anaerobic bacteria glycolysis generation.Short chain fatty acids, which have, to be maintained water-electrolyte balance, colon epithelial cell multiplication is promoted to be given birth to mucous membrane
Long, adjusting intestines immune function adjusts intestinal flora balance, improves the work(such as function of intestinal canal, the expression of anti-inflammatory, antitumor and controlling gene
Effect.Have thousands of piece scholarly journals and Clinical Medical Journals describe the various health care functions of short chain fatty acids and for each
The treatment of kind disease.Such as practical clinical medicine《Short chain fatty acids recognize again》One described in the text short chain fatty acids and leucocyte
Interactively between adhesion molecule, Carcinoma cell differentiation apoptosis elaborates short chain fatty acids in ulcerative colitis, intestinal inflammatory
All many research such as disease, colon cancer, liver cancer, colloid carcinoma and application prospect[3].The annual meeting of the 13rd, Danone nutrition center
《The progress of short chain fatty acids effect and its mechanism》In elaborate short chain fatty acids adjust intestinal flora balance, improve intestines
Road function, the mechanism of action and application prospect of regulation and control ileum, colon gene expression etc.[4]。
Most of ferment is all using galactooligosaccharide as dispensing currently on the market, and galactooligosaccharide enters after human body can only be by
Lactic acid bar A bacterium utilize, and compared to galactooligosaccharide, acid resistance, heat resistance are poor, and available bacterium is more single in body.In addition, city
Publicity effect of ferment is spoken of in general terms on field, is guaranteed to cure all diseases, and ferment product efficacy ingredient is indefinite, and the benefit of short chain fatty acids is not
It is realized, strengthens, products characteristics are not distinct, and ferment product quality is irregular, and What is more, to pursue remarkable efficacy, cause
Consumer's diarrhea, weight gain and other malaise symptoms cause consumer to reduce ferment product degree of belief, promote ferment and purchase again
Rate is difficult.
Ferment is commonly called as " enzyme ", refers to the polymer substance with biocatalytic Activity.Ferment early in last century the fifties just
Begin to appear in Japanese market, but develop it is very slow always, until fruit ferment in 2011 to the benefit of health just by everybody again
Understanding, this has just helped the fast development in ferment market, but consequently also brings many questions of market, such as market ferment product work(
Imitate indefinite, ferment effect is exaggerated strongly, and ferment product quality is irregular, ferment Market Consumer degree of belief is low etc..Mesh
Preceding ferment most of in the market are claimed as enzyme, but enzyme cannot be supplemented by oral taken in by human body in fact.
Dragon fruit, Cactaceae, hylocereus platymiscium are full of nutrition, function is unique, contain the rare plant of general plant
Physical property albumin and anthocyanidin, abundant vitamin and water-soluble dietary fiber, albumin are tool stickiness, collagenous object
Matter has detoxicating functions to heavy metal poisoning.Dragon fruit is sweet flat, and main nutrient composition has protein, dietary fiber, vitamin
B2, vitamin B3, vitamin C, iron, phosphorus, calcium, magnesium, potassium etc..In addition the pericarp of dragon fruit contains the nutrients being of great rarity
Matter --- anthocyanidin, anthocyanidin are a kind of antioxidants of strength, help to prevent a variety of diseases related with free radical.By upper
It understands, dragon fruit has Constipation, and cell membrane is promoted to be formed, and prevents anaemia, and anti-neuritis, angular stomatitis reduce cholesterol, resist
Free radical, anti-old age lesion, anti-colorectal cancer and other effects.And newer result of study is shown, dragon fruit, the juice pair of dragon fruit bough
Positive effect is shown in the illnesss such as the growth of tumour, viral and immune response supression, therefore, dragon fruit is processed into by-product
Product are the inexorable trends of modern dragon fruit planting industry.
Therefore, current dragon fruit ferment product can not meet many health care demands of consumer.
The content of the invention
It is in good taste it is an object of the invention to provide a kind of red heart dragon fruit ferment, it is easily absorbed by the body, effect is complete
Face, economic value are high.
Another object of the present invention is to provide a kind of application of red heart dragon fruit ferment, it can be made into and sticked with regulation and control stomach
Gastrointestinal mucosa, auxiliary treatment gastric ulcer are repaired in theca cell gene expression；It relaxes bowel, adjust intestinal flora environment；Prevent large intestine
Cancer；Improve human body basic metabolism, the health products of hypoglycemic effect.
The present invention is solved its technical problem and is realized using following technical scheme.
The present invention proposes a kind of red heart dragon fruit ferment, is mainly pressed by red heart dragon fruit zymotic fluid and galactooligosaccharide
Weight ratio 10：1~6 is allocated to obtain.
Further, in present pre-ferred embodiments, red heart dragon fruit zymotic fluid is oriented by following raw material using three steps
Fermentation method obtains, and counts in parts by weight, and raw material includes：
Further, in present pre-ferred embodiments, three step orientation fermentation methods are followed successively by aerobic and anaerobic fermentation, completely
Anaerobic fermentation and complete aerobic fermentation.
Further, in present pre-ferred embodiments, aerobic and anaerobic fermentation fermentation temperature is 25~28 DEG C；Completely
The fermentation temperature of anaerobic fermentation is 29~32 DEG C；The fermentation temperature of complete aerobic fermentation is 33~35 DEG C.
Further, in present pre-ferred embodiments, without any lesion, maturity is for the red heart dragon fruit requirement of selection
80%~100%, pulp diameter≤20mm of red heart dragon fruit pulp.
Further, in present pre-ferred embodiments, antimicrobial composition leavening is mainly by Bifidobacterium, plan bar
Pseudomonas, Eubacterium are composed, microbial total number >=8 × 1015cfu/g。
Further, in present pre-ferred embodiments, brown sugar concentrates for very sugar cane crushing.
Further, contain in present pre-ferred embodiments, in red heart dragon fruit ferment thin with regulation and control gastrointestinal mucosa
Cellular gene expression, the short chain fatty acids for repairing gastrointestinal mucosa function.
The present invention proposes a kind of application of above-mentioned red heart dragon fruit ferment, and red heart dragon fruit ferment can be made into raising
Human body basic metabolism, the gene expression of regulation and control gastrointestinal mucosa cells repair gastrointestinal mucosa, auxiliary treatment gastric ulcer, adjust enterobacteriaceae
Group rings border, relaxes bowel, and prevents the health products of colorectal cancer health-care efficacy.
Further, in present pre-ferred embodiments, red heart dragon fruit ferment is diluted to health care with water, honey or fruit juice
Drink.
The red heart dragon fruit ferment of the embodiment of the present invention and its advantageous effect of application are：The red heart fire of the embodiment of the present invention
Imperial fruit ferment is mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide by weight 10：1~6 is allocated to obtain, this is red
Heart dragon fruit ferment is in good taste, is easily absorbed by the body, and effect is comprehensive, and economic value is high.The red heart dragon fruit of the embodiment of the present invention
The application of ferment be can be made into improve human body basic metabolism, the gene expression of regulation and control gastrointestinal mucosa cells, repair gastrointestinal mucosa,
Auxiliary treatment gastric ulcer adjusts intestinal flora environment, relaxes bowel, and prevents the health products of colorectal cancer health-care efficacy.
Description of the drawings
It in order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached
Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair
The restriction of scope, for those of ordinary skill in the art, without creative efforts, can also be according to this
A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the change of blood sugar figure of subject in present invention experiment 1；
Fig. 2 is the Helicobacter pylori infection situation map of patient in present invention experiment 3.
Specific embodiment
It, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
The red heart dragon fruit ferment to the embodiment of the present invention and its application are specifically described below.
The embodiment of the present invention provides a kind of red heart dragon fruit ferment, mainly by red heart dragon fruit zymotic fluid and oligomeric gala
Sugar is allocated, general mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide by weight 10：1~6 allocate
It arrives.
The core functional component of red heart dragon fruit ferment be galactooligosaccharide and short chain fatty acids, wherein, galactooligosaccharide
It is a kind of functional oligose, acidproof, heat-resist, content 90%；Short chain fatty acids be carbon number be 1~6 it is organic
Aliphatic acid.Functional galactooligosaccharide generates short chain fatty acids in colon by anaerobic bacteria glycolysis, with red heart dragon fruit zymotic fluid
Collocation can be rated as perfection.Short chain fatty acids are used to provide energy for intestinal mucosa cells, promote cell metabolism growth；Reduce colon
Environmental pH reduces the growth of harmful bacteria, prevents that function of intestinal canal is disorderly；Inhibit the generation of proinflammatory factor, reduce the generation of inflammation；
Inhibit tumor cell proliferation, control expression of proto-oncogenes, is antitumor.The red heart dragon fruit ferment of the embodiment of the present invention, which has, to be improved
Human body basic metabolism, the gene expression of regulation and control gastrointestinal mucosa cells repair gastrointestinal mucosa, auxiliary treatment gastric ulcer, adjust enterobacteriaceae
Group rings border, relaxes bowel, the health-care efficacies such as prevention colorectal cancer.
Red heart dragon fruit zymotic fluid is obtained by following raw material using three step orientation fermentation methods, and three step orientation fermentation methods are followed successively by
Aerobic and anaerobic fermentation, complete anaerobic fermentation, complete aerobic fermentation.It counts in parts by weight, raw material includes：
The strain that uses of fermenting is the antimicrobial composition leavening that directed screening is turned out using function as guiding, microorganism
Combined fermentation agent is mainly composed with Bifidobacterium, Bacteroides, Eubacterium.
The embodiment of the present invention provides a kind of preparation method of above-mentioned red heart dragon fruit ferment, mainly by red heart dragon fruit
Zymotic fluid and galactooligosaccharide are allocated, and red heart dragon fruit zymotic fluid is obtained by three step orientation fermentation methods, three step orientation fermentations
The novel concept of method enriches the content of red heart dragon fruit zymotic fluid Short-Chain Fatty Acids.The preparation side of red heart dragon fruit ferment
Method specifically includes following steps：
S1, red heart dragon fruit is removed the peel, homogenate, makes pulp diameter≤20cm, obtain red heart dragon fruit pulp, then carry out down
The three step orientation fermentation methods stated.
S2, the first step, aerobic and anaerobic fermentation：It counts in parts by weight, in 100 parts of broken red heart dragon fruit pulps
Adding in 2~10 portions of brown sugar, it then follows saccharomycete dominates the rule of bacterium for primary fermentation, is ventilated in due course or airproof management,
Specific method is：Temperature is controlled at 25~28 DEG C, and daily ventilate to every 2.2~2.7 tons of materials 0.5~1.5m3Mixed fermentation is extremely
22nd~30 day, at this time saccharomycete activity die down, ethanol content value tend to stablize.
Second step, complete anaerobic fermentation：Die down in saccharomycete activity, Sporulated when add in, generally in fermentation the 22nd
~30 days stream plus 3~10 portions of brown sugar and inoculation 0.5~2 portion of antimicrobial composition leavening, antimicrobial composition leavening mainly by
It is simultaneously composed, microorganism group by Shanghai City dragon fruit research institute screening Bifidobacterium, Bacteroides, Eubacterium one by one
Leavening is closed using colony counting method, microbial total number >=8 × 1015Cfu/g, strictly control sends out its anaerobism to fermentation process
Ferment, generates a large amount of short chain fatty acids, and specific method is：Temperature is controlled at 29~32 DEG C, carry out complete anaerobic fermentation to the 40th~
50 days.
3rd step, complete aerobic fermentation：When pH value is again indeclinable, the 40th~50 all kinds of things in nature usually in fermentation
Material pH value is inoculated with 0.3~0.8 part of acetic acid bacteria when no longer changing, and (commercially available acetic acid bacteria, plate count obtain acetic acid bacteria total number >=3
×109Cfu/g aerobic fermentation) is carried out, ethyl alcohol is converted into acetic acid, specific method is：Temperature is controlled at 33~35 DEG C, increases object
Expect dissolved oxygen amount, carry out aerobic fermentation completely and precipitated completely to pomace, filtrate is obtained by filtration.
Make filtrate after-ripening, further oxidation, clarification, until the ethyl alcohol mass fraction content in tunning is less than 0.2%,
Obtain red heart dragon fruit zymotic fluid.
S3, by red heart dragon fruit zymotic fluid and galactooligosaccharide by weight 10：1~6 is allocated, and obtains red heart flue
Fruit ferment.Red heart dragon fruit ferment obtained is high-purity stoste, and acidity is high, and long shelf-life, mouthfeel meta-acid when drinking need to be by original
Liquid dilutes, and can add in other flavouring such as honey, fruit juice according to personal taste.
The embodiment of the present invention provides a kind of application of above-mentioned red heart dragon fruit ferment, and red heart dragon fruit ferment can be made into tool
Human body basic metabolism, the gene expression of regulation and control gastrointestinal mucosa cells are improved, gastrointestinal mucosa, auxiliary treatment gastric ulcer is repaired, adjusts
Intestinal flora environment, relaxes bowel, and prevents the health products of colorectal cancer health-care efficacy, it is generally the case that red heart dragon fruit ferment can
Health beverages are diluted to water, honey or fruit juice.
The red heart dragon fruit ferment of the embodiment of the present invention is allocated by red heart dragon fruit zymotic fluid and galactooligosaccharide, red
Contain red heart dragon fruit nutriment in itself and saccharomycete, antimicrobial composition leavening, acetic acid in heart dragon fruit zymotic fluid
Together through a large amount of short chain fatty acids obtained from everfermentation, functional galactooligosaccharide generates bacterium in colon through anaerobic bacteria glycolysis
Short chain fatty acids.
Short chain fatty acids are used to provide energy for intestinal mucosa cells, promote cell metabolism growth；Reduce colon environment pH
Value, reduces the growth of harmful bacteria, prevents that function of intestinal canal is disorderly；Inhibit the generation of proinflammatory factor, reduce the generation of inflammation；Inhibit swollen
Tumor cell proliferation controls expression of proto-oncogenes, is antitumor.This is because red heart dragon fruit zymotic fluid and oligofructose fermentation generate
Short chain fatty acids mainly include acetic acid, propionic acid, fumaric acid, maleic acid, succinic acid, lactic acid etc..
Exactly because red heart dragon fruit ferment, which is rich in, has the function of 10~20 kinds of above-mentioned short chain fatty acids, therefore this hair
The red heart dragon fruit ferment of bright embodiment have relax bowel, regulate and control gastrointestinal mucosa cellular gene expression, auxiliary treatment gastric ulcer,
It is hypoglycemic, prevention colorectal cancer the effect of, effective percentage more than 90%.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
The present embodiment provides a kind of red heart dragon fruit ferment, mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide
By weight 10：1 is allocated to obtain, and red heart dragon fruit zymotic fluid is fermented by three step orientation fermentation methods, filtered, after-ripening obtains,
Detailed process is as follows：
The first step, aerobic and anaerobic fermentation：Count in parts by weight, take raw material include 100 parts of red heart dragon fruit pulps, 5 parts
Brown sugar, temperature are controlled at 28 DEG C, and daily ventilate to every 2.5 tons of materials 1m3Mixed fermentation 25 days.
Second step, complete anaerobic fermentation：Stream plus 1.0 portions of 5 portions of brown sugar, inoculation antimicrobial composition leavenings, temperature control exist
33 DEG C, complete anaerobic fermentation was to the 40th day.
3rd step, complete aerobic fermentation：0.5 part of commercially available acetic acid bacteria is inoculated with, temperature is controlled at 33 DEG C, daily ventilation 3 times,
Every time ventilate to every 2.5 tons of materials 1m3, complete aerobic fermentation to pomace precipitates completely, and filtrate is obtained by filtration.
Make filtrate after-ripening, further oxidation, clarification, until the ethyl alcohol mass fraction content in tunning is less than 0.2%,
Obtain red heart dragon fruit zymotic fluid.
It counts in parts by weight, 100 portions of red heart dragon fruit zymotic fluids with 1 part of galactooligosaccharide is mixed and are allocated, are obtained
Red heart dragon fruit ferment.
Embodiment 2
The present embodiment provides a kind of red heart dragon fruit ferment, mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide
By weight 10：4 are allocated to obtain, and red heart dragon fruit zymotic fluid is fermented by three step orientation fermentation methods, filtered, after-ripening obtains,
Detailed process is as follows：
The first step, aerobic and anaerobic fermentation：Count in parts by weight, take raw material include 100 parts of red heart dragon fruit pulps, 4 parts
Brown sugar, temperature are controlled at 30 DEG C, and daily ventilate to every 2.5 tons of materials 1m3Mixed fermentation 20 days.
Second step, complete anaerobic fermentation：Stream plus 0.8 portion of 6 portions of brown sugar, inoculation antimicrobial composition leavening, temperature control exist
35 DEG C, complete anaerobic fermentation was to the 38th day.
3rd step, complete aerobic fermentation：0.4 part of commercially available acetic acid bacteria is inoculated with, temperature is controlled at 30 DEG C, daily ventilation 3 times,
Every time ventilate to every 2.5 tons of materials 1m3, complete aerobic fermentation to pomace precipitates completely, and filtrate is obtained by filtration.
Make filtrate after-ripening, further oxidation, clarification, until the ethyl alcohol mass fraction content in tunning is less than 0.2%,
Obtain red heart dragon fruit zymotic fluid.
It counts in parts by weight, 100 portions of red heart dragon fruit zymotic fluids with 4 parts of galactooligosaccharides is mixed and are allocated, are obtained
Red heart dragon fruit ferment.
Embodiment 3
The present embodiment provides a kind of red heart dragon fruit ferment, mainly by red heart dragon fruit zymotic fluid and galactooligosaccharide
By weight 10：5 are allocated to obtain, and red heart dragon fruit zymotic fluid is fermented by three step orientation fermentation methods, filtered, after-ripening obtains,
Detailed process is as follows：
The first step, aerobic and anaerobic fermentation：Count in parts by weight, take raw material include 100 parts of red heart dragon fruit pulps, 6 parts
Brown sugar, temperature are controlled at 25 DEG C, and daily ventilate to every 2.5 tons of materials 1m3Mixed fermentation 30 days.
Second step, complete anaerobic fermentation：Stream plus 1.2 portions of 5 portions of brown sugar, inoculation antimicrobial composition leavenings, temperature control exist
30 DEG C, complete anaerobic fermentation was to the 45th day.
3rd step, complete aerobic fermentation：0.6 part of commercially available acetic acid bacteria is inoculated with, temperature is controlled at 35 DEG C, daily ventilation 3 times,
Every time ventilate to every 2.5 tons of materials 1m3, complete aerobic fermentation to pomace precipitates completely, and filtrate is obtained by filtration.
Make filtrate after-ripening, further oxidation, clarification, until the ethyl alcohol mass fraction content in tunning is less than 0.2%,
Obtain red heart dragon fruit zymotic fluid.
It counts in parts by weight, 100 portions of red heart dragon fruit zymotic fluids with 5 parts of galactooligosaccharides is mixed and are allocated, are obtained
Red heart dragon fruit ferment.
The effect of the present invention is described in further detail below by way of clinical test.This invention address that deep analysis
Ferment product essence, illustrates ferment functional component and effect experiment, for basic metabolism disease, gastrointestinal disease, inflammation, large intestine
The auxiliary treatment purposes of cancer.
(1) test 1- and improve basic metabolism, reduce the verification of blood glucose effect
They are divided into 4 groups by 40 adults with metabolic syndrome of selection.Recommended not according to national standard and supplier
With the usage amount of galactooligosaccharide in food, mix the enzyme stoste of the galactooligosaccharide containing various concentration, every group of subject according to
It is secondary take ferment zymotic fluid group (30ml/ days, name A groups), ferment zymotic fluid adds galactooligosaccharide group (B groups 5g/30ml/ days, C
Group 10g/30ml/ days, D groups 15g/30ml/ days), three months are 1 course for the treatment of.
Curative effect determinate standard is subject to the blood glucose report (4.11~5.89mmol/l of glucose reference value) that hospital shows,
10 people of single group averages.The change of blood sugar of subject is as shown in Figure 1, as can be seen from Figure 1：The ferment of galactooligosaccharide has been added to send out
Zymotic fluid has better effect of lowering blood sugar, and wherein C groups blood sugar decreasing effect is optimal.By trimestral data statistics, 40 tested
Have that blood glucose is substantially reduced in person account for 18, blood glucose be reduced and account for 38, invalid to account for 2, high efficiency is up to 95%.
In this time testing, we are also found surprisingly that, the triglycerides for having 15 patients in 40 subjects has obtained effective control.
(2) verification that 2- repairs gastrointestinal mucosa, auxiliary treatment gastric ulcer effect is tested
40 disease of stomach patients are chosen, every 10 patients are divided into one group, are divided into 4 groups, number consecutively is 1 group of patient,
4 groups of 2 groups of patient, 3 groups of patient and patient.The gastrocopy diagnostic result of all patients shows, they all suffer from chronic superficial-wither
Contracting gastritis, the body of stomach lower part polypoid protuberance of some patients, the stomach redness of some patients is with ulcer.
The patient that 1 group of patient drinks ferment zymotic fluid group 30ml daily, and the patient that 2 groups of patient is drunk daily containing 5g/30ml
Galactooligosaccharide ferment zymotic fluid group, the patient that 3 groups of patient drink the ferment zymotic fluid group of galactooligosaccharide containing 10g/30ml daily,
The patient that 4 groups of patient drinks the ferment zymotic fluid group of galactooligosaccharide containing 15g/30ml daily.It takes mode not require, Huan Zheke
It to drink before meals, can also drink, can directly drink after meal, be drunk after can also being diluted with water.Curative effect determinate standard is to cure
Subject to the gastroscope report that institute shows.
After red heart dragon fruit ferment is taken about 1 year, gastrocopy diagnostic result is shown all patients, their sour regurgitation is swollen
Gas symptom and other state of an illness mitigate, and oesophagus, cardia no abnormality seen, stomach bottom, gastric body mucosa finishing, color and luster is normal, has no swollen object
With ulcer；Continue after taking red heart dragon fruit ferment about half a year, gastrocopy diagnostic result is shown, their stomach ulcer face is complete
Complete to repair, gastritis has obtained controlling well.Especially take the patient of the ferment zymotic fluid group of galactooligosaccharide containing 10g/30ml
Recovery effects it is most rapid.This ineffective 3 of experiment reaction, good 29 of reaction effect, reaction effect general 8
Example, high efficiency is up to 93%.
This experiment illustrates that the red heart dragon fruit ferment of the embodiment of the present invention can regulate and control gastrointestinal mucosa cellular gene expression, repair
The weight ratio of multiple gastrointestinal mucosa, auxiliary treatment gastric ulcer, hot heart dragon fruit zymotic fluid and galactooligosaccharide is 10：3, it allocates
The red heart dragon fruit ferment effect arrived is relatively optimal.
(3) verification that 3- inhibits Helicobacter pylori infection effect is tested
It chooses and positive patient is shown in 40 C14 breath tests, every 10 patients are divided into one group, are divided into 4 groups.Patient 1
The patient of group drinks ferment zymotic fluid group 30ml daily, and the patient that 2 groups of patient drinks the ferment of galactooligosaccharide containing 5g/30ml daily
Zymotic fluid group, the patient that 3 groups of patient drink the ferment zymotic fluid group of galactooligosaccharide containing 10g/30ml, the patient that 4 groups of patient daily
Drink the ferment zymotic fluid group of galactooligosaccharide containing 15g/30ml daily.Bfore meals, extension rate does not require, and is taking ferment
Period, bland diet is needed, eat the food of the stimulating intestine and stomaches mucous membrane such as pungent, strong tea, coffee less.Three months are 1 course for the treatment of, and curative effect is sentenced
Calibration standard is subject to the breath test that hospital shows.
Illustrate the infection conditions of helicobacter pylori, Helicobacter pylori infection such as Fig. 2 institutes of patient with 4 grades
Show.From figure 2 it can be seen that the ferment zymotic fluid of galactooligosaccharide has been added, which to have, preferably prevents Helicobacter pylori infection
Effect, wherein C groups best results, this tests high efficiency up to 100%.
(4) experiment 4- relaxes bowel, the verification of the effect that treats constipation
The white collar of selection sedentary, the women for weight-reducing of dieting are metabolized each 10 of slow the elderly for 60 years old or more,
It is divided into 3 groups.Every group of subject takes ferment zymotic fluid and adds galactooligosaccharide group (10g/30ml/ days) successively, starts to count after 1 week
Trial effect situation carries out efficacy determination with 30 subjects oral account and skin of face situation, mental attitude.By 30
Subject's 1 month tries out situation, ineffective 0 of reaction, good 21 of reaction effect, reaction effect general 9
Example.In addition, the state of mind of 30 subjects is all fine, there is part subject to react evening sleep quality and be improved.This
Experiment illustrates that dragon fruit enzyme stoste has effects that relax bowel well, help digest, and for different crowd, this effect is wide
Spectrality is higher.
In conclusion the red heart dragon fruit ferment of the embodiment of the present invention is easily absorbed by the body, effect is comprehensive, economic value
It is high；The preparation method of red heart dragon fruit ferment is simple, it is easy to accomplish industrialized production；The application of the red heart dragon fruit ferment is can
It is made with regulation and control gastrointestinal mucosa cellular gene expression, repairs gastrointestinal mucosa, auxiliary treatment gastric ulcer；It relaxes bowel, adjust intestines
Road flora environment；Prevent colorectal cancer；Improve the health products of human body basic metabolism.
Embodiments described above is part of the embodiment of the present invention, instead of all the embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts
Every other embodiment, belongs to the scope of protection of the invention.
Bibliography：
[1] Wu Xiangyu, Xu Haiyan, Xin Guoqin, Cao Yinsheng, Wang Mengjuan, Gu Wei；Prebiotics and its application study progress [J],
Animal Husbandry and Feed Science, 2012,33 (10)：27-28.
[2] Zhang Li, Li Kewen；Galactooligosaccharide produces and application technical research progress, food ingredient, 2012.12.
[3] Zhan Yan, Zhi Xinggang；Short chain fatty acids recognize again, practical clinical medicine, and 2007.
[4] progress of Liu Xiaohua, Li Shumei, short chain fatty acids effect and its mechanism, 2010.
Claims (10)
1. a kind of red heart dragon fruit ferment, which is characterized in that it is mainly pressed by red heart dragon fruit zymotic fluid and galactooligosaccharide
Weight ratio 10：1~6 is allocated to obtain.
2. red heart dragon fruit ferment according to claim 1, which is characterized in that the red heart dragon fruit zymotic fluid is by following
Raw material is obtained using three step orientation fermentation methods, is counted in parts by weight, the raw material includes：
3. red heart dragon fruit ferment according to claim 2, which is characterized in that the three steps orientation fermentation method has been followed successively by
Oxygen and anaerobic fermentation, complete anaerobic fermentation and complete aerobic fermentation.
4. red heart dragon fruit ferment according to claim 3, which is characterized in that described aerobic and anaerobic fermentation fermentation temperature
It spends for 25~28 DEG C；The fermentation temperature of the complete anaerobic fermentation is 29~32 DEG C；The fermentation temperature of the complete aerobic fermentation
For 33~35 DEG C.
5. red heart dragon fruit ferment according to claim 2, which is characterized in that the red heart dragon fruit requirement of selection is without any
Lesion, maturity are 80%~100%, pulp diameter≤20mm of the red heart dragon fruit pulp.
6. red heart dragon fruit ferment according to claim 2, which is characterized in that the antimicrobial composition leavening is mainly
It is composed of Bifidobacterium, Bacteroides, Eubacterium, microbial total number >=8 × 1015cfu/g。
7. red heart dragon fruit ferment according to claim 2, which is characterized in that the brown sugar is dense for very sugar cane crushing
It contracts.
8. red heart dragon fruit ferment according to claim 1, which is characterized in that contain tool in the red heart dragon fruit ferment
There are regulation and control gastrointestinal mucosa cellular gene expression, the short chain fatty acids for repairing gastrointestinal mucosa function.
It is 9. a kind of such as the application of red heart dragon fruit ferment described in any item of the claim 1 to 8, which is characterized in that described red
Heart dragon fruit ferment can be made into improve human body basic metabolism, the gene expression of regulation and control gastrointestinal mucosa cells, repair gastrointestinal mucosa,
Auxiliary treatment gastric ulcer adjusts intestinal flora environment, relaxes bowel, and prevents the health products of colorectal cancer health-care efficacy.
10. the application of red heart dragon fruit ferment according to claim 9, which is characterized in that red heart dragon fruit ferment water,
Honey or fruit juice are diluted to health beverages.
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| CN109566944A (en) * | 2019-01-16 | 2019-04-05 | 优牌生物科技有限公司 | A kind of collagen dragon fruit ferment drink with maintenance skin younger state |
| CN112931856A (en) * | 2021-02-07 | 2021-06-11 | 广西民族师范学院 | Preparation method of tropical fruit composite enzyme |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109566944A (en) * | 2019-01-16 | 2019-04-05 | 优牌生物科技有限公司 | A kind of collagen dragon fruit ferment drink with maintenance skin younger state |
| CN112931856A (en) * | 2021-02-07 | 2021-06-11 | 广西民族师范学院 | Preparation method of tropical fruit composite enzyme |
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Application publication date: 20180522 |