CN107836446A - Freezing tube - Google Patents
Freezing tube Download PDFInfo
- Publication number
- CN107836446A CN107836446A CN201711046291.8A CN201711046291A CN107836446A CN 107836446 A CN107836446 A CN 107836446A CN 201711046291 A CN201711046291 A CN 201711046291A CN 107836446 A CN107836446 A CN 107836446A
- Authority
- CN
- China
- Prior art keywords
- cryopreservation tube
- freezing
- storage part
- tube according
- freezing blade
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000007710 freezing Methods 0.000 title claims abstract description 40
- 230000008014 freezing Effects 0.000 title claims abstract description 40
- 238000005138 cryopreservation Methods 0.000 claims abstract description 27
- 238000003860 storage Methods 0.000 claims abstract description 24
- 238000007789 sealing Methods 0.000 claims description 13
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 6
- 229910021529 ammonia Inorganic materials 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims 1
- 238000000151 deposition Methods 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 12
- 239000007788 liquid Substances 0.000 description 6
- 210000001161 mammalian embryo Anatomy 0.000 description 6
- 229910052757 nitrogen Inorganic materials 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 229910001220 stainless steel Inorganic materials 0.000 description 4
- 239000010935 stainless steel Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 238000004017 vitrification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Mechanical Engineering (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a cryopreservation tube which comprises a storage part, a clamping part and an outer sleeve, wherein the clamping part is arranged at one end of the storage part, the outer sleeve is arranged at the other end of the storage part, the storage part comprises a freezing blade, the front end of the freezing blade is spoon-shaped, the outer sleeve comprises a high-speed heat conduction device, a balance rod and a transparent sleeve, the balance rod is of a hollow structure and is sleeved on the high-speed heat conduction device, one end of the transparent sleeve is connected with the balance rod, the other end of the transparent sleeve is sleeved on the freezing blade, and when the front end of the freezing blade obtains an object to be cryopreserved, the transparent sleeve is sleeved on the freezing blade. Above-mentioned cryopreserved pipe is in through setting up high-speed heat-transfer device and balancing stick in the overcoat pipe, work as when the front end of freezing blade acquires to wait to freeze when depositing the thing, will transparent cover in on the freezing blade, will wait to freeze and deposit the thing sealed, when freezing, but high-speed heat-transfer device heat conduction fast freezes to deposit and waits to freeze and deposit the thing.
Description
Technical field
The present invention relates to embryo's storage device field, more particularly to cryopreservation tube field.
Background technology
Human in vitro Fertilization embryo transfer technology widely uses slow freezing, and method for rapidly thawing enters pedestrian's ovum and embryo
Freezen protective, but this method is time-consuming, needs expensive sequencing frigorimeter, and it is poor to egg freezing effect.Developed recently rises
Cryoprotector and supper-fast freezing rate of the vitrification method come using higher concentration, more simply, quickly, it is high
Effect.
Existing cryopreservation tube is that open type glass cryopreservation tube is by a tiny hard handle and one of film band connection one
Individual outer tube composition.Its advantage is to load onto direct plunge into Liquid Nitrogen after embryo, embryo is rapidly reached cryogenic temperature, avoids ice crystal shape
Into.But shortcoming is that embryo directly contacts with liquid nitrogen, it is impossible to prevents from polluting, during tubulature below liquid nitrogen surface, is unfavorable for operating.
The content of the invention
It is an object of the invention to provide a kind of not direct cryopreservation tube easy to operation contacted with liquid nitrogen.
In order to solve the above problems, the invention provides a kind of cryopreservation tube, including storage part, located at described storage part one end
Clamping part, located at the outer tube of the storage part other end, the storage part includes freezing blade, before the freezing blade
Hold includes high-speed heat-conducting device, haltere and transparent sheath for spoon shape, the outer tube, and the haltere is hollow structure and is placed on
The high-speed heat-conducting device, described transparent sheath one end connect the haltere, and the other end is placed on the freezing blade, when described cold
The front end for freezing blade is got when thing is frozen, and the transparent sheath is placed on into the freezing blade.
Above-mentioned cryopreservation tube, by setting high-speed heat-conducting device and haltere in the outer tube, when the freezing blade
Front end get when thing is frozen, by the transparent sheath be placed on it is described freezing blade on, by thing to be frozen seal, when freezing,
The high-speed heat-conducting device can quick conductive, freeze thing to be frozen.
Further, the clamping part is provided with identification and marked, and for recording the essential information of cryopreservation tube, is easy to identify.
Further, the front end of the storage part is provided with the first colour code.
Further, described transparent one end for being placed on the freezing blade is provided with the second colour code.
Further, the haltere surface is provided with groove, is easy to snap frozen.
Further, the haltere is truncated cone-shaped.
Further, after installation, the freezing blade does not contact with the high-speed heat-conducting device.
Further, the top of the freezing blade is tubaeform, is easy to the operation in liquefied ammonia.
Further, the frozen leaf piece tail end is provided with sealing ring, and during sealing, the transparent sheath is placed on the sealing ring
On, increase sealing effectiveness.
Further, the transparent sheath is transparent hose.
Brief description of the drawings
Fig. 1 is the mounting structure schematic diagram for the first embodiment that cryopreservation tube of the present invention provides；
Fig. 2 is the structural representation of the outer tube for the first embodiment that cryopreservation tube of the present invention provides；
Fig. 3 is the structural representation of the storage part for the first embodiment that cryopreservation tube of the present invention provides；
Fig. 4 is the mounting structure schematic diagram for the second embodiment that cryopreservation tube of the present invention provides.
Following embodiment will combine above-mentioned accompanying drawing and further illustrate the present invention.
Embodiment
For the ease of understanding the present invention, the present invention is described more fully below with reference to relevant drawings.In accompanying drawing
Give several embodiments of the present invention.But the present invention can realize in many different forms, however it is not limited to herein
Described embodiment.On the contrary, the purpose for providing these embodiments is made to the disclosure more thorough and comprehensive.
It should be noted that when element is referred to as " being fixedly arranged on " another element, it can be directly on another element
Or there may also be element placed in the middle.When an element is considered as " connection " another element, it can be directly connected to
To another element or it may be simultaneously present centering elements.Term as used herein " vertical ", " horizontal ", " left side ",
" right side " and similar statement are for illustrative purposes only.
Unless otherwise defined, all of technologies and scientific terms used here by the article is with belonging to technical field of the invention
The implication that technical staff is generally understood that is identical.Term used in the description of the invention herein is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein " and/or " include one or more phases
The arbitrary and all combination of the Listed Items of pass.
Fig. 1 to 3 is referred to, the structural representation of the mounting structure schematic diagram, outer tube that are provided for first embodiment of the invention
The structural representation of figure and storage part, including storage part 1, the clamping part 2 located at described one end of storage part 1, located at the storage
The outer tube 3 of portion's other end.
The storage part 1 includes freezing blade 1a, and the front end of the freezing blade 1a is spoon shape, and the outer tube 3 includes
High-speed heat-conducting device 33, haltere 32 and transparent sheath 31, the haltere 32 are hollow structure and are placed on the high speed heat conduction dress
Put 33, described one end of transparent sheath 31 connects the haltere 32, when the front end of the freezing blade 1a is got when thing is frozen,
The transparent sheath 31 is placed on the freezing blade 1a.
Above-mentioned cryopreservation tube, by setting high-speed heat-conducting device 33 and haltere 32 in the outer tube 3, when the freezing
Blade 1a front end is got when thing is frozen, and the transparent sheath 31 is placed on into 1a on the freezing blade, and thing to be frozen is close
Envelope, when freezing, the high-speed heat-conducting device 33 can quick conductive, thing to be frozen is frozen, specifically, the high-speed heat-conducting device 33
It is made using medical grade stainless steel, it is possible to understand that, medical grade stainless steel is mainly made by the nickel of 18% chromium+10%, with
Make its more robust more against corrosion, separated out completely without metal ion, this stainless steel is referred to as medical grade stainless steel, because its is durable and
Complete property, it is mainly used in medicine equipment manufacture and the manufacture of tableware, while the communication that the thermal conductivity for taking into account metal is good
Characteristic..
Specifically, in the present embodiment, the haltere 32 is truncated cone-shaped, it is possible to understand that, the haltere 32 is in work
Influence of stable equilibrium's liquid nitrogen buoyancy to carrier is played in work, and facilitates the conduction of liquid nitrogen cryogenics simultaneously, the frozen leaf
Piece 1a top is tubaeform, is easy to the operation in liquefied ammonia, specifically, in the present embodiment, the transparent sheath 31 is transparent
Sebific duct, after installation, the freezing blade 1a does not contact with the high-speed heat-conducting device 33.
Referring to Fig. 4, the mounting structure schematic diagram of the second embodiment provided for cryopreservation tube of the present invention, described second implements
Example is more or less the same with the first embodiment, and its difference is, in the second embodiment, the clamping part 2 is provided with identification
Mark, for recording the essential information of cryopreservation tube, is easy to identify, it is possible to understand that, the identification mark can be any storage
Frozen in cryopreservation tube word, figure, Quick Response Code of thing relevant information etc. can storage information carrier.
Specifically, in the present embodiment, the front end of the storage part 1 is provided with the first colour code 1b, it is described it is transparent be placed on it is described
One end of freezing blade is provided with the second colour code 31a, during sealing, the first colour code 1b and the second colour code 31a, mutually tightly
Lean on, be easy to identify, specifically, in the present embodiment, the surface of haltere 32 is provided with groove 32a, is easy to snap frozen；It is described
Freezing blade 1a tail ends are provided with sealing ring, and during sealing, the transparent sheath is placed on the sealing ring, increase sealing effectiveness.
Embodiment described above only expresses the several embodiments of the present invention, and its description is more specific and detailed, but simultaneously
Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of cryopreservation tube, including storage part, the clamping part located at described storage part one end, located at the storage part other end
Outer tube, it is characterised in that：The storage part includes freezing blade, and the front end of the freezing blade is spoon shape, the outer tube
Including high-speed heat-conducting device, haltere and transparent sheath, the haltere is hollow structure and is placed on the high-speed heat-conducting device, institute
State transparent sheath one end and connect the haltere, when the front end of the freezing blade is got when thing is frozen, by the transparent sheath
It is placed on the freezing blade.
2. cryopreservation tube according to claim 1, it is characterised in that：The clamping part is provided with identification and marked, and freezes for recording
The essential information of pipe is deposited, is easy to identify.
3. cryopreservation tube according to claim 1, it is characterised in that：The front end of the storage part is provided with the first colour code.
4. cryopreservation tube according to claim 1, it is characterised in that：Described transparent one end for being placed on the freezing blade is provided with
Second colour code.
5. cryopreservation tube according to claim 1, it is characterised in that：The haltere surface is provided with groove, is easy to fast quickly cooling
Freeze.
6. cryopreservation tube according to claim 1, it is characterised in that：The haltere is truncated cone-shaped.
7. cryopreservation tube according to claim 1, it is characterised in that：After installation, the freezing blade and the high speed heat conduction
Device does not contact.
8. cryopreservation tube according to claim 1, it is characterised in that：The top of the freezing blade is tubaeform, is easy to
Operation in liquefied ammonia.
9. cryopreservation tube according to claim 1, it is characterised in that：The frozen leaf piece tail end is provided with sealing ring, during sealing,
The transparent sheath is placed on the sealing ring, increases sealing effectiveness.
10. cryopreservation tube according to claim 1, it is characterised in that：The transparent sheath is transparent hose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711046291.8A CN107836446A (en) | 2017-10-31 | 2017-10-31 | Freezing tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711046291.8A CN107836446A (en) | 2017-10-31 | 2017-10-31 | Freezing tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107836446A true CN107836446A (en) | 2018-03-27 |
Family
ID=61680880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711046291.8A Pending CN107836446A (en) | 2017-10-31 | 2017-10-31 | Freezing tube |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107836446A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108541702A (en) * | 2018-05-30 | 2018-09-18 | 湖北华美阳光生物科技有限公司 | A kind of vitreous with coding information chip freezes bar |
| CN113303324A (en) * | 2021-04-29 | 2021-08-27 | 江西康雅医疗用品有限公司 | Fully-closed quick-freezing vitrification cryopreservation tube |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101314757A (en) * | 2008-07-15 | 2008-12-03 | 四川大学华西第二医院 | Aculeus type tissue slice glassivation refrigeration carrier and refrigeration method for ovary tissue |
| CN101589707A (en) * | 2009-04-23 | 2009-12-02 | 北京微创介入医疗装备有限公司 | Embryo and ovum freezing carrier device for vitrifying in the auxiliary procreation technology |
| US20110129811A1 (en) * | 2009-12-01 | 2011-06-02 | Scitech Invention, Llc | Cryopreservation and Storage Systems and Methods |
| CN202095441U (en) * | 2011-04-25 | 2012-01-04 | 石家庄市第四医院 | Biological material vitrification freezing carrier |
| CN102669088A (en) * | 2012-05-30 | 2012-09-19 | 河南省农业科学院 | Mammal embryo and oocyte vitrification freezing carrier |
| CN203913154U (en) * | 2014-06-27 | 2014-11-05 | 龙文 | Carrying tool for use in vitrification cryo-preservation of biomaterial |
| CN204244993U (en) * | 2014-11-19 | 2015-04-08 | 遵义医学院 | A kind of novel embryo's closed glassization freezing year bar and sleeve pipe |
| CN204616881U (en) * | 2015-04-17 | 2015-09-09 | 万超 | Closed supper-fast vitrified frozen vector |
| CN205922672U (en) * | 2016-07-04 | 2017-02-08 | 浙江省台州医院 | A closed refrigeration year lever apparatus for freezing deposit convoluted seminiferous tubule or sperm |
| CN106489914A (en) * | 2016-10-20 | 2017-03-15 | 北京中仪康卫医疗器械有限公司 | A kind of freezing carries bar |
-
2017
- 2017-10-31 CN CN201711046291.8A patent/CN107836446A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101314757A (en) * | 2008-07-15 | 2008-12-03 | 四川大学华西第二医院 | Aculeus type tissue slice glassivation refrigeration carrier and refrigeration method for ovary tissue |
| CN101589707A (en) * | 2009-04-23 | 2009-12-02 | 北京微创介入医疗装备有限公司 | Embryo and ovum freezing carrier device for vitrifying in the auxiliary procreation technology |
| US20110129811A1 (en) * | 2009-12-01 | 2011-06-02 | Scitech Invention, Llc | Cryopreservation and Storage Systems and Methods |
| CN202095441U (en) * | 2011-04-25 | 2012-01-04 | 石家庄市第四医院 | Biological material vitrification freezing carrier |
| CN102669088A (en) * | 2012-05-30 | 2012-09-19 | 河南省农业科学院 | Mammal embryo and oocyte vitrification freezing carrier |
| CN203913154U (en) * | 2014-06-27 | 2014-11-05 | 龙文 | Carrying tool for use in vitrification cryo-preservation of biomaterial |
| CN204244993U (en) * | 2014-11-19 | 2015-04-08 | 遵义医学院 | A kind of novel embryo's closed glassization freezing year bar and sleeve pipe |
| CN204616881U (en) * | 2015-04-17 | 2015-09-09 | 万超 | Closed supper-fast vitrified frozen vector |
| CN205922672U (en) * | 2016-07-04 | 2017-02-08 | 浙江省台州医院 | A closed refrigeration year lever apparatus for freezing deposit convoluted seminiferous tubule or sperm |
| CN106489914A (en) * | 2016-10-20 | 2017-03-15 | 北京中仪康卫医疗器械有限公司 | A kind of freezing carries bar |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108541702A (en) * | 2018-05-30 | 2018-09-18 | 湖北华美阳光生物科技有限公司 | A kind of vitreous with coding information chip freezes bar |
| CN113303324A (en) * | 2021-04-29 | 2021-08-27 | 江西康雅医疗用品有限公司 | Fully-closed quick-freezing vitrification cryopreservation tube |
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