CN107823389A - 治疗创伤的中药制剂 - Google Patents

治疗创伤的中药制剂 Download PDF

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CN107823389A
CN107823389A CN201711140190.7A CN201711140190A CN107823389A CN 107823389 A CN107823389 A CN 107823389A CN 201711140190 A CN201711140190 A CN 201711140190A CN 107823389 A CN107823389 A CN 107823389A
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高海娟
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Abstract

本发明公开了一种治疗创伤的中药制剂，由以下重量份的中药制剂原料制成：千斤拔30‑46份，荆芥穗25‑30份，川射干21‑29份，九里明13‑26份，了哥王15‑27份，当药11‑17份，卜芥13‑19份，海龙8‑16份，二母宁2‑9份，七叶一枝花2‑9份，桑白皮3‑8份。本发明的治疗创伤的中药制剂，无毒副作用，疗效确切，具有止血止痛快，迅速结痂愈合，从而减少渗出，预防休克，并对感染伤口攻毒敛疮、化腐生肌长皮的功效。

Description

治疗创伤的中药制剂
技术领域
本发明涉及一种治疗创伤的中药制剂。
背景技术
日常生活和医疗中，皮肤创伤是在所难免的，如外伤、手术等都可引起一定的创伤，由于创伤愈合的状况与疾病的病情紧密相关，创伤愈合也因此成为现金医学研究中的重要的热点之一。创伤愈合是指皮肤等组织出现断裂和缺损后的愈复过程。此过程是各种组织的再生和肉芽组织的增生、疤痕形成的复杂组合。从创伤愈合现代概念的描述可以看到它是一个错综复杂的病理过程。其基础是炎症细胞和修复细胞的一系列活动。在软组织损伤中，主要的炎症细胞包括：单核巨噬细胞、中性粒细胞、淋巴细胞等；主要的修复细胞包括：成纤维细胞、内皮细胞、表皮细胞等。这些细胞的活动受到局部和全身因素的影响。根据创伤愈合的现代理论，多种体液介质和细胞介质均能影响炎症细胞和修复细胞的行为，从而参与调控创伤愈合过程。目前，临床处理创伤的方法似乎仍停留在缝合术、清创术、皮肤移植及抗感染等治疗措施，尚缺乏加速伤口愈合的有效方法。能够刺激伤口修复过程的物质是有限的，尽管近来研究报道多种生长因子可促进伤口愈合，但这些物质价格昂贵，其中最重要的是剂量和安全问题。研制一种安全性高、临床疗效好的治疗皮肤创伤的药物具有十分重要的意义。中医中药制剂在治疗创伤中积累了丰富经验，尤其是活血化瘀药在临床上常被用于治疗皮肤溃疡和溃破。而近年来随着中医药事业的茁壮发展，中草药促进创伤愈合的研究也不断涌现。如中国专利申请CN1488377A公开了一种治疗皮肤创伤，疮痂及感染的外用中药制剂，该药物以川楝子鲜果为原料制备得到，但该药物由于成分单一，临床治疗效果欠佳。中国专利CN129277C保护了一种治疗化脓性烫伤的中药制剂，该方缺少相关动物实验或临床数据，其治疗皮肤创伤的实际效果并不确定。纵观世界新药的研究方向，80年代以前主要是研究开发单一的化学药物及其制剂，80年代以后开始发展生物技术和天然植物药物，药物研究方向趋于多样性。结合现代中医药发展理论，从提高药物疗效、降低副作用的角度出发，经过对中药制剂成分进行筛选提取和/或配伍制得的制剂，其副作用小，安全性高，具有化学合成药不能比拟的优势。
发明内容
本发明所要解决的技术问题是：提供一种能使创伤伤口愈合快并在愈合后不留疤痕的治疗创伤的中药制剂。
为解决上述技术问题，本发明采用的技术方案是：
本发明提供的一种治疗创伤的中药制剂，由以下重量份的中药制剂原料制成：千斤拔30-46份，荆芥穗25-30份，川射干21-29份，九里明13-26份，了哥王15-27份，当药11-17份，卜芥13-19份，海龙8-16份，二母宁2-9份，七叶一枝花2-9份，桑白皮3-8份。
优选的，本发明提供的中药制剂由以下重量份的中药制剂原料制成：千斤拔36份，荆芥穗26份，川射干25份，九里明20份，了哥王22份，当药13份，卜芥16份，海龙12份，二母宁5份，七叶一枝花6份，桑白皮5份。
用法与用量：取纯正的中药制剂原料，按照配方将中药制剂混合均匀，混合磨细至80～100目，即成散剂成品。使用时先用碘酒、双氧水清理伤口，然后在伤口撒敷一层药粉，包扎伤口，配合内服清热解毒消炎药物。1-2天换药一次，根据多人次用药实践，一般伤口用药3-5次即可愈合，较深伤口时间稍长。临床病例将本发明用于治疗刀伤及术后切口久不愈合患者，临床疗效观察实验如下：一、疗效评定：显著：切口内脓血敛尽流出，切口不再红肿，切口1-2日愈合；好转：切口内脓血敛尽流出，切口不再红肿，切口3-4日愈合；无效：有少许脓血储留在切口内，切口在10天内不能全部愈合。二、治疗方法：用脱脂棉贴于切口处，在喷涂本发明的中药制剂，1-2天换药一次。三、治疗观察：收治刀伤及术后切口久不愈合患者100例，结果有显著治疗效果的有86例，好转的有14例，无效率为0，总有效率为100％。
本发明的有益效果：
本发明的治疗创伤的中药制剂，无毒副作用，疗效确切，具有止血止痛快，迅速结痂愈合，从而减少渗出，预防休克，并对感染伤口攻毒敛疮、化腐生肌长皮的功效。
具体实施方法
实施例1
本实施例提供的治疗创伤的中药制剂，由以下重量份的中药制剂原料制成：千斤拔36份，荆芥穗26份，川射干25份，九里明20份，了哥王22份，当药13份，卜芥16份，海龙12份，二母宁5份，七叶一枝花6份，桑白皮5份。
典型病例：
1、李某，男，46岁，因砍树被斧头砍伤左脚，伤口长度6厘米、深处3厘米，用药15天伤口愈合，1个月后疤痕消失。
2、张某：女，43岁，被石头磕破脚面，伤口宽度2厘米，深度3厘米，用药20天伤口愈合，2个月后疤痕消失。
3、谢某，男，52岁，因车祸下肢足部多发性开放性损伤，给予清创、消毒、缝合、包扎等处理后，局部用本发明中药外敷，隔日换药一次，2个月后伤口愈合，拆线出院。

Claims (2)

1.一种治疗创伤的中药制剂，其特征在于，由以下重量份的中药制剂原料制成：千斤拔30-46份，荆芥穗25-30份，川射干21-29份，九里明13-26份，了哥王15-27份，当药11-17份，卜芥13-19份，海龙8-16份，二母宁2-9份，七叶一枝花2-9份，桑白皮3-8份。
2.根据权利要求1所述的中药制剂，其特征在于，由以下重量份的中药制剂原料制成：千斤拔36份，荆芥穗26份，川射干25份，九里明20份，了哥王22份，当药13份，卜芥16份，海龙12份，二母宁5份，七叶一枝花6份，桑白皮5份。
CN201711140190.7A 2017-11-16 2017-11-16 治疗创伤的中药制剂 Withdrawn CN107823389A (zh)

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Application publication date: 20180323