CN107812313A - Transcranial magnetic stimulation target point positioning method - Google Patents
Transcranial magnetic stimulation target point positioning method Download PDFInfo
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- CN107812313A CN107812313A CN201711185480.3A CN201711185480A CN107812313A CN 107812313 A CN107812313 A CN 107812313A CN 201711185480 A CN201711185480 A CN 201711185480A CN 107812313 A CN107812313 A CN 107812313A
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- 238000000034 method Methods 0.000 title claims abstract description 18
- 238000011491 transcranial magnetic stimulation Methods 0.000 title claims abstract description 13
- 210000004761 scalp Anatomy 0.000 claims abstract description 37
- 238000002595 magnetic resonance imaging Methods 0.000 claims abstract description 22
- 210000004556 brain Anatomy 0.000 claims abstract description 15
- 210000001259 mesencephalon Anatomy 0.000 claims abstract description 5
- 240000006409 Acacia auriculiformis Species 0.000 claims description 2
- 210000005069 ears Anatomy 0.000 claims description 2
- 230000001815 facial effect Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 2
- 210000003128 head Anatomy 0.000 description 8
- 230000002146 bilateral effect Effects 0.000 description 4
- 206010001497 Agitation Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000001178 neural stem cell Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The present invention relates to medical detection field, and in particular to a kind of transcranial magnetic stimulation target point positioning method, comprises the following steps：（1）Obtain the cranium brain magnetic resonance imaging image of patient；（2）Based on MRI, by calculating the nearest subpoint for searching out region to be stimulated in image midbrain in scalp, the nearest subpoint is referred to as scalp target spot；（3）Based on MRI, index point and scalp target spot are calculated in image at patient's craniofacial region at least three in the minimum distance of scalp surface；（4）It is each radius with the distance of scalp target spot in scalp upper drawing circle with tape respectively using each index point as the center of circle, round intersection point is scalp target spot.The inventive method depends on the calculating of each index point cambered surface distance on Brain MRIs, therefore method is simple and convenient, requirement without large scale equipment, to treating place is low, and cost greatly reduces compared with navigation system.
Description
Technical field
The present invention relates to medical detection field, and in particular to a kind of transcranial magnetic stimulation target point positioning method.
Background technology
Transcranial magnetic stimulation（Transcranial Magnetic Stimulation）It is that a kind of noninvasive nerve intervenes skill
Art.The principle mutually changed based on electromagnetism, the induced field of time-varying, time-varying magnetic field meeting can be produced to stimulating coil fast charging and discharging
Induction field and induced current are produced in tissue, so as to carry out excitability or suppression to the neuron activity in brain tissue
The regulation and control of property.Human brain can be divided into the subprovince of multiple functional specializations, in order to adjust the functional activity of some abnormal brain area without
Other normal brain areas are influenceed, clinically need to find the body surface projection position in specific function area in patient's scalp surface.Due to head
All there is larger individual difference in cranium profile and brain structure, be difficult in the case where no equipment aids in profile and function
The position in the specific region to be stimulated of every patient of precise positioning.To realize this purpose, the product of in the market is mainly by red
Outer navigation system positions, and the system will obtain the three-dimensional head magnetic resonance imaging image of subject, by the structure and scalp of intracerebral
Surface characteristics be mapped, realize the positioning of individuation.However, the equipment price is expensive（More than 800000）, using complicated and
Floor space is big.Also, every patient is also required, treatment every time uses the equipment, thus to the treatment band of transcranial magnetic stimulation
The high cost come.
The content of the invention
In view of the above-mentioned problems, the present invention provides a kind of individuation localization method of transcranial magnetic stimulation target spot.This method is main
Dependent on the calculating of each index point cambered surface distance on Brain MRIs, therefore without large scale equipment and to treatment place
It is it is required that low.
The present invention is achieved by the following technical solutions：
Transcranial magnetic stimulation target point positioning method, comprises the following steps：
（1）Obtain the cranium brain magnetic resonance imaging image of patient；
（2）Based on MRI, region to be stimulated is searched out in image midbrain in the nearest subpoint of scalp by calculating, should
Nearest subpoint is referred to as scalp target spot；
（3）Based on MRI, index point is calculated in image at patient's craniofacial region at least three with scalp target spot in scalp surface
Minimum distance；
（4）It is each radius with the distance of scalp target spot in scalp upper drawing circle with tape respectively using each index point as the center of circle, circle
Intersection point is scalp target spot.
Preferably, step（3）Described craniofacial region index point includes the nasion, left ear minimum point, auris dextra minimum point, left side eye
Angle, right side canthus, occipital protuberance.
The beneficial effects of the present invention are：
The inventive method depends on the calculating of each index point cambered surface distance on Brain MRIs, therefore method is simple
Requirement convenient, without large scale equipment, to treating place is low, and cost greatly reduces compared with navigation system.The present invention is only
Utilize the Brain MRIs of patient and the index point of craniofacial region, you can realize the personalized treatment of Different Individual, single is swept
Tracing greatly reduces time and money cost as can also be used for multiple times.
Brief description of the drawings
Fig. 1 is the schematic diagram of pathway Neural stem cell target point positioning method of the present invention.
Embodiment
To be best understood from the present invention, with reference to embodiment and accompanying drawing, the invention will be further described, following examples
Only it is that the present invention will be described rather than it is limited.
Embodiment 1
Transcranial magnetic stimulation target point positioning method, comprises the following steps：
（1）Obtain the cranium brain magnetic resonance imaging image of patient；
（2）Based on MRI, region to be stimulated is searched out in image midbrain in the nearest subpoint of scalp by calculating, should
Nearest subpoint is referred to as scalp target spot；
（3）Based on MRI, patient's nasion, left and right ear minimum point are calculated in image respectively with scalp target spot in scalp surface
Minimum distance, be designated as A, B, C centimetre respectively；
（4）With tape respectively using the nasion, left and right ear minimum point as the center of circle, A, B, C centimetres be radius in scalp upper drawing circle, three circles
Intersection point be scalp target spot.
As shown in figure 1, the set of number formed in the distance of head any point and the nasion and left and right ear（A、B、C）Have
Uniqueness.Therefore, this method first calculates head certain point and the distance of the nasion and left and right ear on Brain MRIs, so
Measured afterwards in patients head, obtain the position of the scalp target spot, start to treat.
Embodiment 2
Transcranial magnetic stimulation target point positioning method, comprises the following steps：
（1）Obtain the cranium brain magnetic resonance imaging image of patient；
（2）Based on MRI, region to be stimulated is searched out in image midbrain in the nearest subpoint of scalp by calculating, should
Nearest subpoint is referred to as scalp target spot；
（3）Based on MRI, patient's occipital protuberance, bilateral canthus are calculated in image respectively with scalp target spot in scalp surface
Minimum distance, be designated as D, E, F centimetre respectively；
（4）With tape respectively using occipital protuberance, bilateral canthus as the center of circle, D, E, F centimetres be radius in scalp upper drawing circle, three circles
Intersection point be scalp target spot.
The set of number that distance at head any point and occipital protuberance and bilateral canthus is formed（D、E、F）With unique
Property.Therefore, this method first calculates head certain point and occipital protuberance and the distance at bilateral canthus on Brain MRIs,
Then measured in patients head, obtain the position of the scalp target spot, start to treat.
Embodiment described above is only that the preferred embodiment of the present invention is described, and not the scope of the present invention is entered
Row limits, and on the premise of design spirit of the present invention is not departed from, those of ordinary skill in the art make to technical scheme
The various modifications gone out and improvement, it all should fall into the protection domain of claims of the present invention determination.
Claims (2)
1. transcranial magnetic stimulation target point positioning method, it is characterised in that comprise the following steps：
（1）Obtain the cranium brain magnetic resonance imaging image of patient；
（2）Based on MRI, region to be stimulated is searched out in image midbrain in the nearest subpoint of scalp by calculating, should
Nearest subpoint is referred to as scalp target spot；
（3）Based on MRI, index point is calculated in image at patient's craniofacial region at least three with scalp target spot in scalp surface
Minimum distance；
（4）It is each radius with the distance of scalp target spot in scalp upper drawing circle with tape respectively using each index point as the center of circle, circle
Intersection point is scalp target spot.
2. transcranial magnetic stimulation target point positioning method according to claim 1, it is characterised in that：Step（3）Described cranium face
Facial marker point includes the nasion, left ear minimum point, auris dextra minimum point, left side canthus, right side canthus, occipital protuberance.
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| CN107812313A true CN107812313A (en) | 2018-03-20 |
| CN107812313B CN107812313B (en) | 2021-12-31 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109215104A (en) * | 2018-09-04 | 2019-01-15 | 江文涛 | It is a kind of for brain structural images display methods and device through cranium stimulation therapy |
| CN112494810A (en) * | 2020-09-17 | 2021-03-16 | 杭州师范大学 | Repeated transcranial magnetic stimulation method with multi-stimulation target focusing |
| CN113577565A (en) * | 2021-08-05 | 2021-11-02 | 安徽医科大学 | Navigation positioning device of horizontal transcranial magnetic stimulator |
| CN114870261A (en) * | 2022-03-29 | 2022-08-09 | 季公俊 | Scalp target positioning method, system and device based on longitude and latitude concept |
| CN115721861A (en) * | 2022-12-06 | 2023-03-03 | 北京理工大学 | Multi-level neuron transcranial magnetic stimulation method oriented to brain atlas |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109215104A (en) * | 2018-09-04 | 2019-01-15 | 江文涛 | It is a kind of for brain structural images display methods and device through cranium stimulation therapy |
| CN109215104B (en) * | 2018-09-04 | 2023-03-10 | 江文涛 | Brain structure image display method and device for transcranial stimulation treatment |
| CN112494810A (en) * | 2020-09-17 | 2021-03-16 | 杭州师范大学 | Repeated transcranial magnetic stimulation method with multi-stimulation target focusing |
| CN113577565A (en) * | 2021-08-05 | 2021-11-02 | 安徽医科大学 | Navigation positioning device of horizontal transcranial magnetic stimulator |
| CN113577565B (en) * | 2021-08-05 | 2022-03-04 | 安徽医科大学 | Navigation positioning device of horizontal transcranial magnetic stimulator |
| CN114870261A (en) * | 2022-03-29 | 2022-08-09 | 季公俊 | Scalp target positioning method, system and device based on longitude and latitude concept |
| CN114870261B (en) * | 2022-03-29 | 2023-08-18 | 安徽医科大学 | Scalp target positioning method, system and device based on longitude and latitude concepts |
| CN115721861A (en) * | 2022-12-06 | 2023-03-03 | 北京理工大学 | Multi-level neuron transcranial magnetic stimulation method oriented to brain atlas |
| CN115721861B (en) * | 2022-12-06 | 2024-01-23 | 北京理工大学 | Brain-map-oriented multi-level neuron transcranial magnetic stimulation method |
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