CN107801983A - A kind of black fungus rich in selenium ginseng lozenge and preparation method thereof - Google Patents

A kind of black fungus rich in selenium ginseng lozenge and preparation method thereof Download PDF

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Publication number
CN107801983A
CN107801983A CN201711054760.0A CN201711054760A CN107801983A CN 107801983 A CN107801983 A CN 107801983A CN 201711054760 A CN201711054760 A CN 201711054760A CN 107801983 A CN107801983 A CN 107801983A
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China
Prior art keywords
selenium
black fungus
ginseng
rich
fungus rich
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CN201711054760.0A
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Chinese (zh)
Inventor
崔承弼
徐斌
崔泰花
齐欣
常艳秋
池春樱
陈兆双
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Yanbian University
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Yanbian University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • A23P10/28Tabletting; Making food bars by compression of a dry powdered mixture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

A kind of black fungus rich in selenium ginseng lozenge, including following components:Black fungus rich in selenium, people participate in dextrin, sucrose, polyvinylpyrrolidone, magnesium stearate, wherein, the Se content of the black fungus rich in selenium of the black fungus rich in selenium is 10 milligrams/100 grams, and organic selenium content is more than 80% 90%;The ginseng grows white recluse's ginseng for 5 years for artificial growth.Medicine in lozenge of the present invention should have diffluent property, have the characteristics that action speed is fast, conveniently take, be easy to carry, to absorb fast, applicable crowd wide;The selenium-enriched black fungus ginseng lozenge of the present invention is while not only contain black fungus rich in selenium and ginseng nutrient and medical value, the various advantages such as also conveniently takes, is easy to carry with lozenge.

Description

A kind of black fungus rich in selenium ginseng lozenge and preparation method thereof
Technical field
The invention belongs to field of Chinese herbal, and in particular to a kind of black fungus rich in selenium ginseng lozenge and preparation method thereof.
Background technology
Black fungus is one of famous edible mushroom in China, and its yield and quality occupy first place in the world, and black fungus quality is delicate, sliding It is crisp and refreshing mouth, delicious pure and fresh, unique, nutritious, therefore " meat or fish in element ", " Vegetable meat " are referred to as, and it is considered as " mountain delicacy ".It is black Agaric protein content is higher than general vegetables and fruit, containing amino acid necessary to the mankind, and contains multivitamin, and it is not It is only nutritious, and medical value is also very high, has " QI invigorating is not hungry, moistening lung cerebrum tonifying, strong will of making light of one's life by commiting suicide and blood are supported and held " and other effects, The polysaccharide body that it contains has obvious inhibitory action to cancer cell.
Ginseng is the dry root and rhizome of Araliaceae, from the good reputation for beginning to possess " kings of hundred grass " so far, people's handle Ginseng, fur and pilose antler are collectively referred to as " northeast Triratna ", and the superfine product of " strengthening the body resistance to consolidate the constitution, life is mended in enriching yin " is more described as by oriental medicine circle. With enhancing memory, anti-aging, raising immunity, anti-oxidant, improvement systema cariovasculare functional, resisting stress, establishing-Yang and resist Tumour etc. acts on, and ginsenoside can also play a part of modifications and changes brain cell membrane structure, so as to change the characteristic of cell With reinforcement cell function.Its many bioactive ingredients is that researcher is of interest, and especially 2012 by state food medicine Supervision and management general bureau is approved as new resource food, obtains the study hotspot of domestic and international field of medicaments.
Problems be present in black fungus rich in selenium and ginseng food at present, one is due to that black fungus rich in selenium contains a large amount of glue Matter, eating method routinely are not easy to chew absorption and utilization rotten, therefore that be unfavorable for human body.Second, healthcare function is single.People Ginseng lozenge equally exists the defects of being difficult to be absorbed by the body.
The content of the invention
Black fungus is that a kind of dietotherapeutic is worth higher mountain delicacy food, and there are some researches show black fungus has very strong Selenium rich ability, and have studied cultivation and its nutritional ingredient of selenium-rich agaric.Ginseng is China's tradition rare traditional Chinese medicine again, but black The research of agaric and ginseng lozenge has not been reported.In view of this, it is an object of the invention to provide a kind of black fungus rich in selenium people Join lozenge, including following components:Black fungus rich in selenium, people participate in auxiliary material.
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the black fungus rich in selenium, the weight ratio of ginseng are 1:1。
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the black fungus rich in selenium, ginseng are pulverizer powder 100 mesh sieves are crossed after broken.
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the auxiliary material includes filler, sweetener, sticked Mixture, wetting agent, the one or more of lubricant.
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the auxiliary material is dextrin, sucrose, polyethylene pyrrole Pyrrolidone, magnesium stearate.
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the black fungus rich in selenium people participates in the ratio of auxiliary material Example is black fungus rich in selenium and ginseng 19.87%, dextrin 39.73%, sucrose 19.87%, polyvinylpyrrolidone 19.87%, hard Fatty acid magnesium 0.66%.
Preferably, in black fungus rich in selenium ginseng lozenge of the present invention, the black fungus rich in selenium of the black fungus rich in selenium Se content is 10 milligrams/100 grams, and wherein organic selenium content is more than 80%-90%;The ginseng is lifes in 5 years of artificial growth Changbai Mountain ginseng.
Another aspect of the invention is a kind of preparation method of black fungus rich in selenium ginseng lozenge is provided, comprise the following steps:
Black fungus rich in selenium, ginseng are ground into the selenium-enriched black fungus ginseng lozenge raw material powder of 100 purposes with pulverizer, mixed The raw material powder, softwood processed, granulation, drying, lubricant, tabletting are added, after packaged sterilizing, become selenium-enriched black fungus people Join lozenge.
Preferably, in the preparation method of black fungus rich in selenium ginseng lozenge of the present invention, the black fungus rich in selenium, ginseng Weight ratio be 1:1.
Preferably, in the preparation method of black fungus rich in selenium ginseng lozenge of the present invention, described kind of black fungus rich in selenium people Black fungus rich in selenium, the weight ratio of people's participation auxiliary material are in ginseng lozenge:Black fungus rich in selenium and ginseng 19.87%, dextrin 39.73%, Sucrose 19.87%, polyvinylpyrrolidone 19.87%, magnesium stearate 0.66%.
The present invention is joined as raw material with the white recluse that grow for 5 years of black fungus rich in selenium and artificial growth, to black fungus rich in selenium ginseng Composition proportion and processing technology are studied in lozenge.Black fungus rich in selenium and ginseng are cleaned into drying, mistake after being crushed with pulverizer 100 eye mesh screens.In order to obtain the preferable black fungus rich in selenium ginseng lozenge of quality, it need to add and fill out into black fungus rich in selenium ginseng lozenge The auxiliary materials such as agent, sweetener, binder and wetting agent and lubricant are filled, the formula of black fungus rich in selenium ginseng lozenge is determined by testing And each component ratio.After raw material is well mixed by a certain percentage with filler, adds binder and wetting agent adjustment material sticks Right and wettability, neither too hard, nor too soft softwood is obtained, then cross 20 mesh sieves and be granulated.The particle of gained is put into vertical forced air drying Dried in case.Lubricant is added in obtained dry particle and is well mixed, is sent into tablet press machine and carries out tabletting.Then from piece Quality evaluation is carried out to black fungus rich in selenium ginseng lozenge in terms of weight differential, hardness, finally carries out sensory evaluation again.Pass through formula Design experiment, it is determined that the optimum formula of black fungus rich in selenium ginseng lozenge is black fungus rich in selenium and ginseng, dextrin, sucrose and poly- second Alkene pyrrolidone.Optimal proportioning is black fungus rich in selenium ginseng 19.87%, dextrin 39.73%, sucrose 19.87%, polyethylene pyrrole Pyrrolidone 19.87%, magnesium stearate 0.66%.
Compared with prior art, the present invention has advantages below to the present invention:
1) present invention is the Changbai Mountain ginseng using selenium-enriched black fungus and 5 years raw artificial growths, after carrying out ultramicro grinding, Lozenge is made, refers to after being put into oral cavity, can slowly dissolve, effect and tablet locally or systemically.Medicine in lozenge should have Have diffluent property, can by sublingual mucosa and oral cavity buccal surface mucosal absorption, can reach topical anti-inflammatory, sterilization, convergence, Analgesic or local anaesthesia effect.Have the characteristics that action speed is fast, conveniently take, be easy to carry, to absorb fast, applicable crowd wide.
2) selenium-enriched black fungus ginseng lozenge of the invention not only contains black fungus rich in selenium and ginseng nutrient and medical value While, the various advantages such as also conveniently take, be easy to carry with lozenge.So the present invention is from black fungus rich in selenium ginseng Raw material, the processing technology of black fungus rich in selenium ginseng lozenge is studied, be that the diversity of black fungus rich in selenium Ginseng Products is developed Provide fundamental basis.Contain chip technology using black fungus rich in selenium ginseng in manufacture craft, overcome lozenge production to greatest extent The simplification of technique and convenient purification.
Embodiment
Below in conjunction with the embodiment in the present invention, the technical scheme in the present invention is clearly and completely described.It is aobvious So, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Based on the reality in the present invention Example is applied, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, is all belonged to In the scope of protection of the invention.
The preparation method of the black fungus rich in selenium ginseng lozenge of embodiment 1
1) raw material:Selenium-enriched black fungus (10 milligrams/100 grams of selenium content, wherein organic selenium content are more than 80%-90%) With each 10 grams of the Changbai Mountain ginseng of 5 years raw artificial growths.
2) formula that black fungus rich in selenium ginseng lozenge is determined by testing is 1:1.
Black fungus rich in selenium and ginseng are cleaned into drying, 100 eye mesh screens are crossed after being crushed with pulverizer.By the selenium-rich black wood of acquisition Ear ginseng raw feed powder is mixed, and after raw material is well mixed by a certain percentage with filler, adds binder and wetting agent is adjusted Whole material degree of adhesion and wettability, obtain neither too hard, nor too soft softwood, then cross 20 mesh sieves and are granulated.The particle of gained is put into vertical Dried in air dry oven.Lubricant is added in obtained dry particle and is well mixed, is sent into tablet press machine and carries out tabletting.
3) quality evaluation is carried out to black fungus rich in selenium ginseng lozenge in terms of sheet weight difference, hardness, finally felt again Official evaluates.
By being formulated design experiment, it is determined that the optimum formula of black fungus rich in selenium ginseng lozenge is black fungus rich in selenium and people Ginseng, dextrin, sucrose and polyvinylpyrrolidone.Optimal proportioning is black fungus rich in selenium ginseng 19.87%, dextrin 39.73%, sugarcane Sugar 19.87%, polyvinylpyrrolidone 19.87%, magnesium stearate 0.66%.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (10)

1. a kind of black fungus rich in selenium ginseng lozenge, including following components:Black fungus rich in selenium, people participate in auxiliary material.
2. black fungus rich in selenium ginseng lozenge according to claim 1, it is characterised in that the black fungus rich in selenium, ginseng Weight ratio is 1:1.
3. black fungus rich in selenium ginseng lozenge according to claim 1, it is characterised in that the black fungus rich in selenium, ginseng are Pulverizer crosses 100 mesh sieves after crushing.
4. black fungus rich in selenium ginseng lozenge according to claim 1, it is characterised in that the auxiliary material includes filler, sweet tea Taste agent, binder, wetting agent, the one or more of lubricant.
5. black fungus rich in selenium ginseng lozenge according to claim 1, it is characterised in that the auxiliary material is dextrin, sucrose, gathered Vinylpyrrolidone, magnesium stearate.
6. black fungus rich in selenium ginseng lozenge according to claim 1, it is characterised in that the black fungus rich in selenium people participates in auxiliary The ratio of material is black fungus rich in selenium and ginseng 19.87%, dextrin 39.73%, sucrose 19.87%, polyvinylpyrrolidone 19.87%th, magnesium stearate 0.66%.
7. the black fungus rich in selenium ginseng lozenge according to any one of claim 1~6, it is characterised in that the selenium-rich black wood The Se content of the black fungus rich in selenium of ear is 10 milligrams/100 grams, and wherein organic selenium content is more than 80%-90%;The ginseng is 5 years of artificial growth grow white recluse's ginseng.
8. a kind of preparation method of black fungus rich in selenium ginseng lozenge, comprises the following steps:
Black fungus rich in selenium, ginseng are ground into the selenium-enriched black fungus ginseng lozenge raw material powder of 100 purposes with pulverizer, described in mixing Raw material powder, softwood processed, granulation, drying, lubricant, tabletting are added, after packaged sterilizing, become selenium-enriched black fungus ginseng and contain Piece.
9. the preparation method of black fungus rich in selenium ginseng lozenge according to claim 7, it is characterised in that the selenium-rich black wood Ear, the weight ratio of ginseng are 1:1.
10. the preparation method of black fungus rich in selenium ginseng lozenge according to claim 8, it is characterised in that described kind of selenium-rich Black fungus rich in selenium, the weight ratio of people's participation auxiliary material are in black fungus ginseng lozenge:Black fungus rich in selenium and ginseng 19.87%, dextrin 39.73%th, sucrose 19.87%, polyvinylpyrrolidone 19.87%, magnesium stearate 0.66%.
CN201711054760.0A 2017-11-01 2017-11-01 A kind of black fungus rich in selenium ginseng lozenge and preparation method thereof Pending CN107801983A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116210909A (en) * 2022-12-09 2023-06-06 上海壹块硒健康科技有限公司 Selenium supplementing ginseng plant selenium tablet for enhancing immunity

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CN102988477A (en) * 2012-11-29 2013-03-27 *** Black fungus capsule
CN103463151A (en) * 2013-08-15 2013-12-25 吉林省和升圆生物科技有限公司 Method for producing pure mountain ginseng lozenge
US20150096575A1 (en) * 2013-10-03 2015-04-09 Altria Client Services Inc. Tobacco lozenge
CN105558529A (en) * 2014-10-13 2016-05-11 邵雷 Health foodstuff

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Publication number Priority date Publication date Assignee Title
CN101073409A (en) * 2006-05-19 2007-11-21 金文庆 Multipurpose medicinal edible food
CN102988477A (en) * 2012-11-29 2013-03-27 *** Black fungus capsule
CN103463151A (en) * 2013-08-15 2013-12-25 吉林省和升圆生物科技有限公司 Method for producing pure mountain ginseng lozenge
US20150096575A1 (en) * 2013-10-03 2015-04-09 Altria Client Services Inc. Tobacco lozenge
CN105558529A (en) * 2014-10-13 2016-05-11 邵雷 Health foodstuff

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116210909A (en) * 2022-12-09 2023-06-06 上海壹块硒健康科技有限公司 Selenium supplementing ginseng plant selenium tablet for enhancing immunity

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