CN107788980A - Microwave thermoacoustic colorful ultrasonic bimodal nutrient infusion amount detecting device and method - Google Patents
Microwave thermoacoustic colorful ultrasonic bimodal nutrient infusion amount detecting device and method Download PDFInfo
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/0507—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves using microwaves or terahertz waves
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4312—Breast evaluation or disorder diagnosis
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0825—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the breast, e.g. mammography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/488—Diagnostic techniques involving Doppler signals
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
- A61B8/5246—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from the same or different imaging techniques, e.g. color Doppler and B-mode
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
- A61B8/5261—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
Abstract
The present invention provides microwave thermoacoustic colorful ultrasonic bimodal nutrient infusion amount detecting device and method.Its device includes function generator, microwave generator, sample cell, data collecting card and computer etc., function generator launches pulse train, triggering microwave generator sends pulse microwave, emitted antenna is uniformly irradiated onto test serum, test serum absorbs microwave energy and causes transient temperature rise, thermoacoustic effect is produced, mechanical energy is converted heat into and is radiate with ultrasound modalities；Computer carries out image reconstruction process using backprojection algorithm, obtains microwave thermoacoustic and the imaging of ultrasonic double-mode state, calculate nutrient infusion amount according to the thermoacoustic that data collecting card gathers and ultrasonic time-domain signal.The present invention can detect nutriment distribution and intensity, display nutriment flow direction and flowing velocity in the blood vessel in blood, the information of the nutrition content flowed through with obtaining in the unit interval, the tumor of breast to early stage provide an effective diagnostic mode.
Description
Technical field
The present invention relates to Medical Imaging Technology, is specially that one kind is based on microwave thermoacoustic and color ultrasound image technology, merges
Two kinds of imaging modes, it is directed to detecting device and the side of nutrient infusion amount parameter (nutrition content that the unit interval is flowed through)
Method.
Background technology
Angiography is applied to detect various diseases, such as tumour, atherosclerosis, angiocardiopathy
Deng.Magnetic resonance imaging (MRI), positron emission computerized tomography (PET) and computed tomography (CT) are that conventional blood vessel faces
Bed general inspection instrument.MRI and PET has good resolution ratio and high specific；However, because fancy price, they are simultaneously
It is not widely used.CT is there is also some limitations, such as ionising radiation and thin vessels difficult in imaging.
Color Doppler imaging is a kind of clinical diagnosis technology being widely used, and can determine whether internal organs position, quickly
Intuitively show vascular distribution, direction and VPV, but Color Doppler Imaging essence or ultrasonic imaging, its contrast according to
It is so very low.Microwave thermoacoustic imaging is using pulse microwave as excitaton source, based on the microwave absorption difference inside biological tissue, is had
Good image contrast, while the function information on molecular level can also be obtained.Blood contains a variety of nutriments, such as
Protein, vitamin, amino acid (AA), glucose (Glu) and most of inorganic salts, these materials have very strong microwave to inhale
Receive.
The content of the invention
In order to solve the problems of prior art, the present invention provides microwave thermoacoustic-colorful ultrasonic bimodal nutrition and filled
Fluence detection means, based on microwave thermoacoustic and CDFI bimodal imaging system, the battalion in blood can be detected
Material distribution and intensity are supported, simultaneously, nutriment flow direction and flowing velocity in the blood vessel can also be shown, is come with this
The information of the nutrition content flowed through in the unit interval is obtained, the tumor of breast to early stage provides an effective diagnosis side
Formula.
The present invention also provides microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion quantity measuring method.
Detection means of the present invention adopts the following technical scheme that：Microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion amount detection
Device, including function generator, microwave generator, transmitting antenna, ultrasonic reception and emitter, amplifier, sample cell, data
Capture card and computer, computer difference and function generator, data collecting card connection；Microwave generator and function generator connects
Connect, the emitted antenna transmission of pulse signal of transmitting is placed in sample cell to sample cell, test serum；
Function generator launches pulse train, and triggering microwave generator sends pulse microwave, the emitted uniform spoke of antenna
Shine in test serum, test serum absorbs microwave energy and causes transient temperature rise, and adiabatic expansion occurs, and produces thermoacoustic effect, will
Heat energy is converted into mechanical energy and radiate with ultrasound modalities；Ultrasonic reception and emitter are used to receive, launch ultrasonic wave letter
Number with thermoacoustic signal, ultrasound signal transmission is to the ultrasonic time-domain signal collection of data collecting card progress, and thermoacoustic signal is through amplifier
Data collecting card is transferred to after processing and carries out thermoacoustic time-domain signal collection；The thermoacoustic that computer is gathered according to data collecting card with
The time-domain signal of ultrasound, image reconstruction process is carried out using backprojection algorithm, obtain microwave thermoacoustic and the imaging of ultrasonic double-mode state, and
Bimodal imaging according to obtaining calculates nutrient infusion amount.
Preferably, the microwave generator is arranged on the lower section of sample cell with transmitting antenna；The ultrasonic reception and transmitting
Device is arranged on the top of sample cell.
Detection method is based on above-mentioned microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion amount detecting device, including
Following steps：
(1) in the sample cell for being placed on test serum；
(2) connect and open microwave generator, data collecting card, computer, function generator, amplifier, and ginseng is set
Number, is waited to be detected；
(3) pulse microwave is produced using the pulse train triggering microwave generator of function generator transmitting；Pulse microwave passes through
Transmitting antenna is transferred in sample cell, and test serum absorbs microwave energy and causes transient temperature rise, and thermoacoustic signal is converted into ultrasonic letter
Number it is transferred on ultrasonic reception and emitter, the time-domain signal of data collecting card collection thermoacoustic signal and ultrasonic signal, with RAW
Form storage；
(4) time-domain signal of thermoacoustic signal and ultrasonic signal is imported in computer, image is carried out using backprojection algorithm
Reconstruction is handled, and obtains microwave thermoacoustic and the imaging of ultrasonic double-mode state；
(5) bimodal imaging data is stored；
(6) data analysis is carried out according to obtained bimodal imaging, calculated, try to achieve nutrient infusion amount.
The present invention is had the following advantages relative to prior art and effect：
1st, not only contrast is high for thermal acoustic imaging, and has high-resolution, and high imaging depth, fire damage is small, and signal to noise ratio is high
The advantages of；Color ultrasound image can position to pathological tissues, it is possible to provide focus clearly border, coating and shape information,
The flow rate information of detectable blood.The present invention detects microwave thermoacoustic and colorful ultrasonic bimodal for blood vessel imaging, can not only
It is enough that blood vessel is positioned, there is provided the structural images of vascular tissue's high-resolution high-contrast, additionally it is possible to detect unit interval stream
The polar molecule content crossed, i.e. nutrient infusion amount.
2nd, pathological tissues are compared with normal surrounding tissue, capilary more crypto set, and faster, United microwave of the present invention is warm for metabolism
Sound and CDFI bimodal imaging system can obtain unit interval nutrition content in blood, to monitor blood
The consumption of middle nutriment, a new diagnostic tool is provided for the tumor of breast of early stage.
3rd, apparatus of the present invention system bulk is small, in light weight, working stability, continuous operating time length, easy to use, cost
Low, energy-output ratio is small；For realizing that the clinicization of thermoacoustic and color ultrasound technology has huge impetus.
Brief description of the drawings
Fig. 1 is the detects schematic diagram of vascular nutrition groundwater increment；
Fig. 2 is based on microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion amount detecting device signal in the embodiment of the present invention
Figure；
Fig. 3 is the timing diagram of microwave thermoacoustic and the imaging of colorful ultrasonic bimodal；
Fig. 4 is the thermoacoustic of simulated blood vessel, color ultrasound image experiment, wherein (a) is the essence of lower same concentrations different in flow rate
The bimodal image of the propylhomoserin aqueous solution, (b) are the bimodal images of the opposed polarity molecule aqueous solution under identical flow velocity.
Embodiment
With reference to embodiment and accompanying drawing, the present invention is described in further detail, but embodiments of the present invention are unlimited
In this.
Embodiment
Fig. 1 illustrates the detection of vascular nutrition groundwater increment, wherein C1、C2What is represented is nutriment intensity, d1、d2Represent
Be vessel cross-sections diameter, v1、v2What is represented is the flow velocity of cross section at this.Such as Fig. 2, the present embodiment be based on microwave thermoacoustic-
Colorful ultrasonic bimodal nutrient infusion amount parameter detection device, including function generator 2-1, microwave generator 2-2, transmitting antenna
2-3, ultrasonic reception and emitter 2-6, couplant 2-5, sample cell 2-7, amplifier 2-8, dc source 2-9, data acquisition
Block 2-10, computer 2-11 and display, computer difference and function generator, data collecting card, display connection, ultrasound connects
Receive and emitter, amplifier, data collecting card are sequentially connected；Microwave generator and function generator connects, the pulse of transmitting
The emitted antenna transmission of signal is full of couplant 2-5, test serum 2-4 is placed on sample to sample cell 2-7 lower section in sample cell
In product pond.Ultrasonic reception and emitter are arranged on the top of sample cell.
Microwave generator is High-Power Microwave generator, and tranmitting frequency 0.5-30GHz, pulsewidth is that 0.001-1 μ s are optional,
It is optional to launch pulse peak power 10-1000KW, the pulse microwave of 1-10K continuously adjustabe of repetition rate.The present embodiment it is micro-
Wave source selects the microwave generator (BW6000HPT) of the micro electronmechanical Science and Technology Ltd. in Shaanxi north, its tranmitting frequency 6GHz, and pulsewidth is
1 μ s, launch pulse peak power 80KW, the pulse microwave of 500 continuously adjustabes of repetition rate.
Function generator, setting frequency range are 1-1000Hz, and amplitude 1-50vpp, pulsewidth is 0.001-100 μ s.Hair
Penetrate antenna to be used to radiate High-Power Microwave, be shaped as circular horn, gain ranging 1-100dB, for radiating High-Power Microwave, this
The bore of transmitting antenna is preferably 110mm in embodiment, and gain is preferably 3dB.
Sample cell is used to place testing sample, and long a width of 20-30cm, material is stainless steel, keeps constant temperature, constant pressure, is not easy
It is deformation, corrosion-resistant, high temperature resistant, easy cleaning, replaceable.Couplant is a kind of water soluble polymer colloid, and it is for excluding to surpass
Air between sound reception and emitter and test serum, ultrasonic wave energy is effectively penetrated test serum and reach effective detection
Purpose, optional mineral oil is as couplant.
Dc source is connected with amplifier, provides DC voltage for amplifier, the range of nominal tension is in 6-12V.Due to heat
Acoustical signal is weaker than ultrasonic signal, and the present invention is using No. 128 amplifier amplification thermoacoustic signals, and the multiplication factor of amplifier is in 40-200
Times, number of active lanes scope is in 1-1024；The multiplication factor of the preferred amplifier of the present embodiment is 50 times.
It for 1-1024, frequency range is the super of 0.5MHz-75MHz that ultrasonic reception and emitter, which use number of active lanes scope,
Sonic transducer, for launching and receiving ultrasonic signal；The preferred more array elements of dominant frequency 2.5MHz of the present embodiment are linearly popped one's head in, and can be launched
Ultrasound, can also receive ultrasound, number of active lanes 128, and relative bandwidth is 70% or so.
Data collecting card and computer can carry out data acquisition and imaging.Data collecting card is used to gather thermoacoustic and ultrasound
Time-domain signal, stored in the form of three-dimensional matrice (points x port number x wave numbers), points scope is 1-4096, range of channel's number
For 1-1024, wave-number range 100-200.Data collecting card resolution ratio is 12 in the present embodiment, sample rate 50MS/s, is adopted
Sample rate meets that collection requires.At the i7-4790K double-cores of central processor CPU model 4GHz Intel Core 2 of computer
Device is managed, meets calculating speed requirement；Realize that backprojection algorithm carries out image reconstruction process using MATLAB or other software, obtain
Microwave thermoacoustic and the imaging of ultrasonic double-mode state.
The operation principle of detection means of the present invention is：Function generator launches pulse train, and triggering microwave generator is sent
Pulse microwave, emitted antenna are uniformly irradiated onto test serum, and test serum absorbs microwave energy and causes transient temperature rise, this
Shi Weibo pulsewidth is narrow, and thermal diffusion can not occur in microwave pulse duration for the energy of absorption, and adiabatic expansion occurs,
Thermoacoustic effect is produced, i.e. heat energy is converted into mechanical energy and radiate with ultrasound modalities.Linear array ultrasonic probe is accessed into microwave source,
Ultrasonic reception and emitter launch ultrasonic wave to blood vessel, and thermoacoustic signal and ultrasonic signal are converted into electric signal by ultrasonic transducer
And pass in data collecting card, the thermoacoustic signal after the amplification of external trigger and ultrasonic signal are gathered simultaneously, the time domain collected
Signal in a computer after filtering Inverse Projection it is reducible go out microwave thermoacoustic and color ultrasound image.Microwave thermoacoustic imaging is used for
The Strength Changes of nutriment are detected, color ultrasound image is used for the change for detecting flow velocity.As shown in figure 1, C1、C2Represent be
The intensity of nutriment, d1、d2Represent be cross section diameter, v1、v2Represent be cross section at this flow velocity, utilize with
Lower formula detects the change of nutrient infusion amount：
Image reconstruction is carried out in computer：The microwave thermoacoustic and the initial data of ultrasound collected, i.e. time-domain signal
By three-dimensional matrice (points x port number x wave numbers)) in the form of preserve, by removing Beam numbers, to two-dimensional matrix, (points x leads to
Road number) initial data carry out image reconstruction using backprojection algorithm, final available a fusion microwave thermoacoustic and ultrasound
Image.
Microwave thermoacoustic and sequential such as Fig. 3 of colorful ultrasonic bimodal imaging, each one group of image of two kinds of imaging patterns can be 1
Completed in millisecond, so can be under same set of data collecting card, while obtain two kinds of imaging patterns with a piece of imaging region
Image, and do not interfere with each other.Fig. 4 simulates the thermoacoustic of blood vessel, color ultrasound image experiment, wherein under (a) is different in flow rate
The bimodal imaging of the arginine aqueous solution of same concentrations, (b) is the bimodal of the opposed polarity molecule aqueous solution under identical flow velocity
Imaging.
Detection method is based on above-mentioned microwave thermoacoustic-ultrasonic double-mode state nutrient infusion amount detecting device, including following
Step：
(1) test serum is placed in the sample cell full of couplant (mineral oil).
(2) connect and open microwave generator, data collecting card, computer, function generator, dc source, amplifier
Etc. equipment, arrange parameter, wait to be detected.
(3) pulse microwave is produced using the pulse train triggering microwave generator of function generator transmitting；Pulse microwave passes through
Transmitting antenna is transferred in sample cell, and test serum absorbs microwave energy and causes transient temperature rise, and thermoacoustic signal is converted into ultrasonic letter
Number it is transferred on ultrasonic reception and emitter (ultrasonic probe), the time domain of data collecting card collection thermoacoustic signal and ultrasonic signal
Signal, initial data is stored in the form of RAW.
(4) thermoacoustic and ultrasonic time-domain signal are imported in computer, image weight is carried out using MATLAB backprojection algorithm
Processing is built, obtains microwave thermoacoustic and the imaging of ultrasonic double-mode state.
(5) store bimodal imaging data and close each equipment.
(6) data analysis is carried out according to obtained bimodal imaging, calculated, nutrient infusion amount is tried to achieve by formula (1).
Example is embodied as with above-mentioned, is better embodiment of the present invention, but the present invention is not only applicable to this mode, it is other
Any Spirit Essence without departing from the present invention with made under principle change, modification, replacement, combine, simplification, should be equivalent
Substitute mode, it is included within protection scope of the present invention.
Claims (10)
1. microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion amount detecting device, it is characterised in that including function generator, micro-
Wave producer, transmitting antenna, ultrasonic reception and emitter, amplifier, sample cell, data collecting card and computer, computer
And function generator, data collecting card connection respectively；Microwave generator and function generator connects, and the pulse signal of transmitting is through hair
Antenna transmission is penetrated to be placed in sample cell to sample cell, test serum；
Function generator launches pulse train, and triggering microwave generator sends pulse microwave, and emitted antenna uniformly arrive by irradiation
In test serum, test serum absorbs microwave energy and causes transient temperature rise, and adiabatic expansion occurs, and thermoacoustic effect is produced, by heat energy
Mechanical energy is converted into radiate with ultrasound modalities；Ultrasonic reception and emitter be used to receiving, launch ultrasonic signal and
Thermoacoustic signal, ultrasound signal transmission to data collecting card carry out ultrasonic time-domain signal collection, and thermoacoustic signal is handled through amplifier
After be transferred to data collecting card carry out thermoacoustic time-domain signal collection；Computer is according to the thermoacoustic that data collecting card is gathered and ultrasound
Time-domain signal, using backprojection algorithm carry out image reconstruction process, obtain microwave thermoacoustic and ultrasonic double-mode state imaging, and according to
Obtained bimodal imaging calculates nutrient infusion amount.
2. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the microwave generator is arranged on the lower section of sample cell with transmitting antenna；The ultrasonic reception and emitter are arranged on sample
The top in product pond.
3. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the sample cell is interior to be full of couplant.
4. microwave thermoacoustic according to claim 3-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the couplant is water soluble polymer colloid.
5. microwave thermoacoustic according to claim 3-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the couplant is mineral oil.
6. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the calculation formula of the nutrient infusion amount is：
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Wherein C1、C2Represent be nutriment intensity, d1、d2Represent be cross section diameter, v1、v2What is represented is at this
The flow velocity of cross section.
7. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the tranmitting frequency of the microwave generator is 0.5-30GHz, and pulsewidth is 0.001-1 μ s.
8. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the frequency range of the function generator is 1-1000Hz, and amplitude 1-50vpp, pulsewidth is 0.001-100 μ s.
9. microwave thermoacoustic according to claim 1-colorful ultrasonic bimodal nutrient infusion amount detecting device, its feature exist
In the transmitting antenna is electromagnetic horn；The ultrasonic reception and emitter use number of active lanes scope as 1-1024, frequency
Scope is 0.5MHz-75MHz ultrasonic transducer.
10. based on microwave thermoacoustic any one of claim 1-9-colorful ultrasonic bimodal nutrient infusion amount detecting device
Microwave thermoacoustic-colorful ultrasonic bimodal nutrient infusion quantity measuring method, it is characterised in that comprise the following steps：
(1) in the sample cell for being placed on test serum；
(2) connect and open microwave generator, data collecting card, computer, function generator, amplifier, and arrange parameter, etc.
It is to be detected；
(3) pulse microwave is produced using the pulse train triggering microwave generator of function generator transmitting；Pulse microwave is emitted
Antenna transmission is into sample cell, and test serum absorbs microwave energy and causes transient temperature rise, and thermoacoustic signal is converted into ultrasonic signal biography
It is defeated on ultrasonic reception and emitter, the time-domain signal of data collecting card collection thermoacoustic signal and ultrasonic signal, with RAW shape
Formula stores；
(4) time-domain signal of thermoacoustic signal and ultrasonic signal is imported in computer, image reconstruction is carried out using backprojection algorithm
Processing, obtain microwave thermoacoustic and the imaging of ultrasonic double-mode state；
(5) bimodal imaging data is stored；
(6) data analysis is carried out according to obtained bimodal imaging, calculated, try to achieve nutrient infusion amount.
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| CN110742588A (en) * | 2019-10-28 | 2020-02-04 | 四川大学华西医院 | Microwave thermoacoustic, photoacoustic and ultrasonic three-mode intestinal tissue imaging method and system |
| CN112782279A (en) * | 2019-11-07 | 2021-05-11 | 华南师范大学 | Non-contact thermoacoustic imaging method and device |
| CN113640319A (en) * | 2021-08-06 | 2021-11-12 | 电子科技大学 | Snowflake beef imaging device based on microwave thermoacoustic technology |
| CN113820398A (en) * | 2021-09-30 | 2021-12-21 | 电子科技大学 | Polarized microwave thermoacoustic imaging device and method |
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