CN107668047A - A kind of ternary weeding composition containing pyraflufen-ethyl - Google Patents

Abstract

The invention discloses a kind of ternary weeding composition containing pyraflufen-ethyl and its application, effective active composition is made up of the first active component pyraflufen-ethyl, the second active component florasulam and the chlorine of 2 first of the 3rd active component 4 or derivatives thereof, the percentage by weight that pyraflufen-ethyl accounts for the composition is 1%~20%, the percentage by weight that florasulam accounts for the composition is that the percentage by weight that chlorine of 0.1~10%, 2 first 4 or derivatives thereof accounts for the composition is 10~50%.This composition can be configured to wettable powder, water dispersible granules, suspending agent, dispersible oil-suspending agent, microemulsion, the suspension emulsion agriculturally allowed.Instant component is reasonable, it is good in cornfield herbicidal effect, and its activity and herbicidal effect are not the simple superposition of each component activity, compared with existing unitary agent or binary built preparation, in addition to significant herbicidal effect, and there is significant synergistic effect, dosage is reduced, herbicide controlling spectrum increases, good to crop safety.

Description

A kind of ternary weeding composition containing pyraflufen-ethyl

Technical field

The present invention relates to a kind of cornfield herbicidal composition, by active component pyraflufen-ethyl, florasulam and the chlorine of 2 first 4 and helps Agent forms, and belongs to technical field of compounded pesticide.

Background technology

Pyraflufen-ethyl, English name pyraflufen-ethyl, chemical name are the chloro- 5- of 2- (the chloro- 5- difluoromethoxies of 4- Base -1- methylpyrazole -3- bases) -4- fluorophenoxyacetate ethyl esters.The medicine is contact phenylpyrazole class postemergence weed control Agent, its mechanism of action is to suppress the oxidizing ferment of protoporphyrin 4 in plant, and the difference for being absorbed and being deposited to medicine using wheat and weeds The metabolin of different activities produced by different, reach the effect for optionally preventing and treating wheatland weeds.

Florasulam, English name florasulam, chemical name are：The fluoro- 5- ethyoxyls -8- fluorine of 2', 6'- bis- [1,2,4] triazole [1,5-c] pyrimidine -2- sulfonanilides, triazolopyrimidine sulfonamides superelevation effective herbicide, closed for acetolactic acid Into enzyme（ALS）Inhibitor, be inner-adsorption conduction-type herbicide, can conduct to weeds complete stool, thus herbicide is thorough, Bu Huifu Hair.Efficacy stability at low temperature, even at 2 DEG C, still ensure that stable drug effect.Double fluorine sulphur grass press broad weed-killing spectrum, can prevent and kill off The most broad leaved weed of wheatland, including the difficult anti-weeds such as clearvers, corn gromwell, and to be most difficult in wheatland anti-wartwort have it is extraordinary Inhibitory action.

The chlorine of 2 first 4, English name MCPA, chemical name are 2-methyl-4-chlorophenoxyacetic acid, are selected for phenoxy acetic acid class Property Uptake and translocation hormone like herbicide, the conducting tissue of dicotyledon can be destroyed, making to grow is interfered, cauline leaf turn round Song, basal part of stem expand thicker or cracking, can effectively prevent and kill off rice field major part sedge weed and broad leaved weed.Dichloro quinolinic acid Belong to hormone herbicide, can be absorbed by rudiment barnyard grass seed root and blade, not strict is required to soil moisture content, is being moistened In the case of can play drug effect, for rice seedling bed, live field and transplant field, can effectively prevent and treat barnyard grass and other weeds, individually Using easily to producing poisoning when stubble crop and succession crop.

The chlorine derivative of 2 first 4 may be selected from 2- methyl -4- chlorobenzene benzene oxygen isopropyl acid (the also known as chlorine isopropyl acid of 2 first 4), 2- methyl -4- Chlorobenzene phenoxy butyric acid (also known as Thistrol), 2- methyl -4- chlorobenzene phenoxy butyric acids butyl ester (also known as Thistrol butyl ester), 2 The different monooctyl ester of the chlorine of first 4, the chloroethene thioester of 2 first 4, the thio second fat of the chlorine of 2 first 4, the chlorine sodium salt of 2 first 4, the chlorine sylvite of 2 first 4 or the chlorine isopropylamine of 2 first 4 Salt.

The different monooctyl ester of the chlorine of 2 first 4, English name MCPA-isooctyl, chemical name are that methoxone is different Monooctyl ester.The different monooctyl ester of the chlorine of 2 first 4 is agriculturally being used as plant growth regulator, prevents the fruit early stage fruit drop such as tomato, and formed S.m.p fruit, promote early ripening of the crops, accelerate rooting of cuttings.Also herbicide can be made, for after seedling cauline leaf process, easily by more and leaf portion Absorb and conduct, for granule cereal, rice, pea, lawn and noncrop area bud rear defence except a variety of annual and perennial wealthy Leaf weeds.

Applicant has found do not have still pyraflufen-ethyl, florasulam and the chlorine of 2 first 4 or derivatives thereof three to answer at present through retrieval The composition patent matched somebody with somebody.Simultaneously by long-term experiment it was unexpectedly observed that by the different pyraflufen-ethyl of the mechanism of action, florasulam With the chlorine of 2 first 4 or derivatives thereof compounding, there is obvious synergy to make to weeds such as clearvers, Veronica, chickweed, Descurainia sophia, shepherd's purses With significantly improving the prevention effect to broad leaved weed, expand herbicide controlling spectrum, reduce dosage, reduce cost accounting, improve pair Crop safety.

The content of the invention

It is an object of the invention to provide a kind of component is reasonable, drug cost is low, and synergistic effect is notable, and herbicidal effect is good, Preventing and treating spectrum is wide, to the ternary weeding composition containing pyraflufen-ethyl of crop safety.

Another object of the present invention is to provide the ternary weeding composition preparation formulation containing pyraflufen-ethyl.

It is still another object of the present invention to provide application of the above-mentioned composition on preventing and treating cornfield gramineae weed.

The defects of in order to overcome existing unitary agent or two-spot to compound, the technical scheme of Herbicidal combinations of the present invention is so Solve：

A）First active component pyraflufen-ethyl；

B）Second active component florasulam；

C）Chlorine of 3rd active component, 2 first 4 or derivatives thereof.

The percentage by weight that pyraflufen-ethyl accounts for the composition is 1%~20%, and florasulam accounts for the weight of the composition Percentage is that the percentage by weight that chlorine of 0.1~10%, 2 first 4 or derivatives thereof accounts for the composition is 10~50%.

A kind of ternary weeding composition containing pyraflufen-ethyl of the present invention is according to the method well known to those skilled in the art of the present technique The preparation formulation that can be prepared is wettable powder, water dispersible granules, suspending agent, dispersible oil-suspending agent, microemulsion, outstanding breast Agent.

To wettable powder, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, polyoxyethylene gather Oxypropylene group ether block copolymers, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, poly alkyl alcohol One or more in oxygen ethene ether phosphate, alkylphenol-polyethenoxy base ether sulfonate etc.；Wetting agent such as alkyl sulfate, alkane One or more in base sulfonate, alkylnaphthalene sulfonate etc.；Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, height One or more in ridge soil, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, clay etc..

To water dispersible granules, workable auxiliary agent has：Dispersant such as polycarboxylate（TERSPERSE 2700、T36、GY- D06 etc.）, lignosulfonates, the one or more in alkylnaphthalene sulfonate etc.；Wetting agent such as alkyl sulfate, alkyl sulfonic acid One or more in salt, naphthalene sulfonate etc.；Disintegrant such as ammonium sulfate, sodium sulphate, polyvinylpyrrolidone, starch and its derivative One or more in thing, bentonite etc.；Binding agent such as starch, glucose, polyvinyl alcohol, polyethylene glycol, carboxymethyl cellulose One or more in sodium, sucrose etc.；Filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, clay One or more in.

To suspending agent, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, alkyl naphthalene formaldehyde condensation Thing sulfonate, alkylphenol-polyethenoxy base ether phosphate, alkylphenol-polyethenoxy base ether sulfonate, phenethyl phenol polyoxyethylene groups Ether phosphate, alkyl polyoxyethylene ether sulfonate, polyoxyethylene polyoxypropylene base ether block copolymers, pull open powder, dodecyl One or more in polyoxyethylene ether phosphate etc.；Wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, Phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfate, alkylsulfonate, alkylnaphthalene sulfonate, alkylphenol-formaldehyde resin One or more in APEO, triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer etc.；Thickener such as Huang One kind in virgin rubber, polyvinyl alcohol, bentonite, aluminium-magnesium silicate, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose etc. It is or a variety of；One or more in preservative such as formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, OIT；Defoaming Agent such as silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 aliphatic alcohols, hexanol, butanol, octanol etc. In one or more；In antifreezing agent such as ethylene glycol, propane diols, glycerine, polyethylene glycol, sorbierite, urea, inorganic salts One or more；Water is deionized water.

To dispersible oil-suspending agent, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene Sulfonate（Dispersing agent NNO）、TERSPERSE 2020（Huntsman Corporation of U.S. HUNTSMAN produces, alkyl naphthalene sulfonic acid salt）Deng In one or more；Emulsifying agent such as BY（Castor oil polyoxyethylene ether）Serial emulsifying agent（BY-110、BY-125、BY-140）、 Nongru-700 #（Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast 2201, this disk -60#（Sorbitan monostearate）, tell Temperature -60#（Sorbitan monostearate APEO）, agriculture breast 1601#（Phenethyl phenol polyoxyethylene polyoxypropylene Ether）、TERSPERSE 4894（Huntsman Corporation of the U.S. produces）One or more in；Wetting agent such as alkylphenol-polyethenoxy Base ether formaldehyde condensation products sulfate, APES phosphate, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfide Hydrochlorate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500（Huntsman Corporation of the U.S. produces）One or more in； One or more in thickener such as white carbon, polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Antifreezing agent such as ethylene glycol, the third two One or more in alcohol, glycerine, urea, inorganic salts such as sodium chloride；Decentralized medium for example soybean oil, rapeseed oil, small wheat oil, One or more in methyl oleate, diesel oil, machine oil, mineral oil etc..

To microemulsion, workable auxiliary agent has：Emulsifying agent such as agriculture breast 500#（Calcium dodecyl benzene sulfonate）, Nongru-700 #, Agriculture breast 2201, this disk-60#, polysorbate60-#, TX-10, agriculture breast 1601（Phenethyl phenol polyoxyethylene poly-oxygen propylene aether）, agriculture breast One or more in 600#, agriculture breast 400# etc.；One kind or more in assistant for emulsifying agent such as methanol, isopropanol, n-butanol, ethanol Kind；Solvent such as cyclohexanone, 1-METHYLPYRROLIDONE, dimethylbenzene, toluene, solvent naphtha（The trade mark：S-150、S-180、S-200）In One or more；One or more in stabilizer such as triphenyl phosphite, epoxychloropropane；Water is deionized water.

To suspension emulsion, workable auxiliary agent has：Emulsifying agent such as calcium dodecyl benzene sulfonate（Agriculture breast 500#）, Nongru-700 #, Agriculture breast 2201, this disk -60#, emulsifying agent T-60（Common name：Anhydrous sorbitol single-hard ester acid ester APEO）、TX-10（It is logical With name：Octyl phenol polyoxyethylene（10）Ether）, agriculture breast 1601#, agriculture breast 600#, the one or more in agriculture breast 400#；Dispersant is such as It is one or more in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Solvent such as repefral, adjacent benzene two It is one or more in formic acid dibutyl ester, ethyl acetate, methyl benzoate；Defoamer is as such as silicone oil, silicone compound, C10-20 One or more in saturated fat acids compound, C8-10 aliphatic alcohols, hexanol, butanol, octanol；Thickener such as white carbon, It is one or more in polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Antifreeze such as ethylene glycol, propane diols, glycerine, urea, inorganic salts Such as one or more in sodium chloride；Water is deionized water.

Instant component is reasonable, and herbicidal effect is good, and drug cost is low, and its activity and herbicidal effect are not each component activity Simple superposition, but have significant synergistic effect, control of weeds spectrum can be expanded, delaying drug resistance is good to crop safety, meets The security requirement of pesticidal preparations.The present invention has good prevention effect to wheatland broad leaved weed.

Embodiment

Illustrate pyraflufen-ethyl, florasulam and the chlorine of 2 first 4 or derivatives thereof compounding to wheat below by Toxicity Determination The synergistic effect of field broad leaved weed.

In order to prevent and treat wheatland broad leaved weed, we are entered with pyraflufen-ethyl, florasulam and the chlorine of 2 first 4 or the different monooctyl ester of the chlorine of 2 first 4 Gone mutual compounding synergy research, test method reference《People's Republic of China (PRC) agricultural industry criteria NY/T1155.4- The part of 2006 farm-chemical indoor determination test rule herbicide the 4th：Active determination test cauline leaf spray-on process》With《Middle Chinese The part of people republic agricultural industry criteria NY/T1155.7-2006 farm-chemical indoor determination test rules herbicide the 7th： The synergy measure of mixture》.

Subjects are wheatland clearvers（Galium aparine）, Veronica（Veronica didyma）, chickweed （Stellaria media）, Descurainia sophia（Descurainia sophia）, shepherd's purse（Capsella bursa-pastoris）.

The test medicine that active compound is configured to need, single dose and each compound drug are set into 5 various concentrations gradients first （It is different according to dosages distribution on the basis of pilot study result, concentration gradient set it is also different, prevent and kill off rate 5%~ Set in the range of 90% by geometric progression）.If clear water compares, it is repeated 4 times.Weeds were in for 2~3 leaf phases, from low dosage to high agent Amount carries out spraying treatment respectively.It is placed in after processing in greenhouse and cultivates observation, the moisturizing in a manner of the bottom infiltrating irrigation of basin alms bowl.

21 days after the processing fresh weight preventive effects for calculating each chemicals treatment, pass through the probit value of preventive effect and the logarithm value of series concentration Between linear regression analysis, obtain the ED of each medicament₅₀Value, the co-toxicity coefficient of mixture is calculated with the abundant methods of Sun Yun（CTC）, come with this Evaluate activity of the reagent agent to weeds.

Co-toxicity coefficient CTC >=120 of complex preparation show as synergistic effect；CTC≤80 show as antagonism；80 ＜ CTC ＜ 120 show as summation action.

The pyraflufen-ethyl of table 1, florasulam are combined to clearvers toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.26	100.00	-	-
Florasulam（B）	1.35	241.48	-	-
					The chlorine of 2 first 4（C）	359.63	0.91	-	-
A:B:C=4:8:10	2.36	138.14	106.41	129.82
					A:B:C=10:4:30	4.95	65.86	45.30	145.39
A:B:C=20:6:50	4.32	75.46	45.98	164.13
					A:B:C=12:10:24	2.85	114.39	79.06	144.69
A:B:C=6:5:20	3.69	88.35	58.89	150.02
					A:B:C=8:1:40	9.34	34.90	21.99	158.69
A:B:C=2:0.1:12	11.53	28.27	16.67	169.63
					A:B:C=16:9:45	3.82	85.34	54.49	156.62
A:B:C=14:2:14	3.26	100.00	63.19	158.26
					A:B:C=18:3:26	4.15	78.55	54.21	144.90
A:B:C=1:7:16	3.38	96.45	75.20	128.25

The pyraflufen-ethyl of table 2, florasulam are combined to Veronica toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.87	100.00	-	-
Florasulam（B）	1.14	339.47	-	-
					The chlorine of 2 first 4（C）	386.31	1.00	-	-
A:B:C=4:8:10	2.16	179.17	142.08	126.10
					A:B:C=10:4:30	5.34	72.47	54.27	133.54
A:B:C=20:6:50	5.15	75.15	53.78	139.74
					A:B:C=12:10:24	2.61	148.28	100.41	147.67
A:B:C=6:5:20	3.59	107.80	74.75	144.20
					A:B:C=8:1:40	9.36	41.35	24.07	171.76
A:B:C=2:0.1:12	13.25	29.21	17.44	167.43
					A:B:C=16:9:45	3.69	104.88	67.15	156.19
A:B:C=14:2:14	3.69	104.88	69.77	150.33
					A:B:C=18:3:26	4.36	88.76	60.52	146.66
A:B:C=1:7:16	2.89	133.91	103.85	128.95

The pyraflufen-ethyl of table 3, florasulam are combined to chickweed toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.54	100.00	-	-
Florasulam（B）	1.69	209.47	-	-
					The chlorine of 2 first 4（C）	326.75	1.08	-	-
A:B:C=4:8:10	2.97	119.19	94.84	125.67
					A:B:C=10:4:30	5.46	64.84	42.51	152.52
A:B:C=20:6:50	5.02	70.52	43.57	161.87
					A:B:C=12:10:24	2.85	124.21	72.19	172.06
A:B:C=6:5:20	4.68	75.64	53.84	140.50
					A:B:C=8:1:40	10.23	34.60	21.49	161.06
A:B:C=2:0.1:12	12.87	27.51	16.59	165.78
					A:B:C=16:9:45	4.82	73.44	50.49	145.48
A:B:C=14:2:14	4.34	81.57	61.14	133.42
					A:B:C=18:3:26	4.87	72.69	52.27	139.07
A:B:C=1:7:16	4.18	84.69	65.98	128.35

The pyraflufen-ethyl of table 4, florasulam are combined to Descurainia sophia toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	4.21	100.00	-	-
Florasulam（B）	2.03	207.39	-	-
					The chlorine of 2 first 4（C）	339.86	1.24	-	-
A:B:C=4:8:10	3.46	121.68	94.16	129.22
					A:B:C=10:4:30	7.21	58.39	42.43	137.63
A:B:C=20:6:50	6.64	63.40	43.50	145.74
					A:B:C=12:10:24	3.58	117.60	71.82	163.74
A:B:C=6:5:20	5.16	81.59	53.60	152.21
					A:B:C=8:1:40	11.59	36.32	21.57	168.40
A:B:C=2:0.1:12	16.37	25.72	16.71	153.91
					A:B:C=16:9:45	5.94	70.88	50.32	140.86
A:B:C=14:2:14	4.26	98.83	61.07	161.82
					A:B:C=18:3:26	5.28	79.73	52.22	152.69
A:B:C=1:7:16	4.67	90.15	65.48	137.67

The pyraflufen-ethyl of table 5, florasulam are combined to shepherd's purse toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.97	100.00	-	-
Florasulam（B）	1.24	320.16	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	315.97	1.26	-	-
A:B:C=4:8:10	2.18	182.11	135.18	134.72
					A:B:C=10:4:30	4.94	80.36	52.69	152.52
A:B:C=20:6:50	4.72	84.11	52.42	160.46
					A:B:C=12:10:24	2.69	147.58	96.34	153.19
A:B:C=6:5:20	3.38	117.46	71.80	163.58
					A:B:C=8:1:40	9.62	41.27	23.89	172.77
A:B:C=2:0.1:12	13.68	29.02	17.52	165.60
					A:B:C=16:9:45	3.63	109.37	64.83	168.70
A:B:C=14:2:14	4.05	98.02	68.60	142.90
					A:B:C=18:3:26	5.12	77.54	59.43	130.47
A:B:C=1:7:16	3.21	123.68	98.38	125.71

The pyraflufen-ethyl of table 6, florasulam are combined to clearvers toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.26	100.00	-	-
Florasulam（B）	1.35	241.48	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	163.58	1.99	-	-
A:B:C=4:8:10	2.21	147.51	106.90	137.99
					A:B:C=10:4:30	5.02	64.94	46.04	141.06
A:B:C=20:6:50	4.45	73.26	46.69	156.90
					A:B:C=12:10:24	2.39	136.40	79.62	171.31
A:B:C=6:5:20	3.26	100.00	59.59	167.82
					A:B:C=8:1:40	8.57	38.04	22.88	166.25
A:B:C=2:0.1:12	11.24	29.00	17.59	164.86
					A:B:C=16:9:45	3.53	92.35	55.19	167.35
A:B:C=14:2:14	3.19	102.19	63.70	160.44
					A:B:C=18:3:26	4.02	81.09	54.81	147.94
A:B:C=1:7:16	3.14	103.82	75.93	136.74

The pyraflufen-ethyl of table 7, florasulam are combined to Veronica toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.87	100.00	-	-
Florasulam（B）	1.14	339.47	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	174.52	2.22	-	-
A:B:C=4:8:10	1.97	196.45	142.63	137.73
					A:B:C=10:4:30	4.85	79.79	55.10	144.82
A:B:C=20:6:50	4.82	80.29	54.58	147.12
					A:B:C=12:10:24	2.36	163.98	101.04	162.29
A:B:C=6:5:20	3.05	126.89	75.54	167.97
					A:B:C=8:1:40	9.17	42.20	25.06	168.38
A:B:C=2:0.1:12	13.59	28.48	18.48	154.10
					A:B:C=16:9:45	3.27	118.35	67.93	174.22
A:B:C=14:2:14	3.37	114.84	70.33	163.28
					A:B:C=18:3:26	4.18	92.58	61.19	151.30
A:B:C=1:7:16	2.61	148.28	104.66	141.68

The pyraflufen-ethyl of table 8, florasulam are combined to chickweed toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.54	100.00	-	-
Florasulam（B）	1.69	209.47	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	154.23	2.30	-	-
A:B:C=4:8:10	2.84	124.65	95.40	130.66
					A:B:C=10:4:30	5.52	64.13	43.33	147.99
A:B:C=20:6:50	4.97	71.23	44.36	160.56
					A:B:C=12:10:24	2.96	119.59	72.82	164.23
A:B:C=6:5:20	4.12	85.92	54.62	157.31
					A:B:C=8:1:40	9.36	37.82	22.48	168.28
A:B:C=2:0.1:12	12.24	28.92	17.62	164.11
					A:B:C=16:9:45	4.53	78.15	51.26	152.44
A:B:C=14:2:14	3.93	90.08	61.70	145.99
					A:B:C=18:3:26	4.65	76.13	52.94	143.81
A:B:C=1:7:16	3.97	89.17	66.79	133.50

The pyraflufen-ethyl of table 9, florasulam are combined to Descurainia sophia toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	4.21	100.00	-	-
Florasulam（B）	2.03	207.39	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	136.94	3.07	-	-
A:B:C=4:8:10	3.23	130.34	94.99	137.21
					A:B:C=10:4:30	6.68	63.02	43.68	144.30
A:B:C=20:6:50	6.23	67.58	44.71	151.14
					A:B:C=12:10:24	3.42	123.10	72.78	169.15
A:B:C=6:5:20	4.61	91.32	54.79	166.68
					A:B:C=8:1:40	10.89	38.66	23.07	167.58
A:B:C=2:0.1:12	15.46	27.23	18.27	149.04
					A:B:C=16:9:45	5.32	79.14	51.50	153.67
A:B:C=14:2:14	4.56	92.32	61.93	149.09
					A:B:C=18:3:26	5.36	78.54	53.24	147.54
A:B:C=1:7:16	4.86	86.63	66.70	129.86

The pyraflufen-ethyl of table 10, florasulam are combined to shepherd's purse toxicity test with the chlorine of 2 first 4

Chemicals treatment	ED50（Ga.i./mu）	ATI	TTI	CTC
					Pyraflufen-ethyl（A）	3.97	100.00	-	-
Florasulam（B）	1.24	320.16	-	-
					The different monooctyl ester of the chlorine of 2 first 4（C）	142.59	2.78	-	-
A:B:C=4:8:10	2.36	168.22	135.87	123.81
					A:B:C=10:4:30	4.82	82.37	53.73	153.29
A:B:C=20:6:50	4.98	79.72	53.42	149.22
					A:B:C=12:10:24	2.37	167.51	97.14	172.44
A:B:C=6:5:20	3.13	126.84	72.79	174.25
					A:B:C=8:1:40	9.35	42.46	25.13	168.94
A:B:C=2:0.1:12	12.94	30.68	18.82	162.98
					A:B:C=16:9:45	3.93	101.02	65.81	153.50
A:B:C=14:2:14	3.95	100.51	69.31	145.01
					A:B:C=18:3:26	4.69	84.65	60.27	140.44
A:B:C=1:7:16	2.95	134.58	99.40	135.38

Toxicity Determination result shows：The 10~20% of composition are accounted for according to pyraflufen-ethyl content, florasulam content accounts for combination 10~50% ratio that the 0.1~10% of thing, the chlorine of 2 first 4 or the different monooctyl ester content of the chlorine of 2 first 4 account for composition is used with, to clearvers, mother-in-law Procumbent speedwell, chickweed, Descurainia sophia, shepherd's purse have preferable virulence, and co-toxicity coefficient CTC is synergistic effect all greater than 120.

In order to which the present invention is better described, present invention is described further with reference to embodiment, the percentage in formula Than being weight percentage.

Example of formulations 1

10% pyraflufen-ethyl, 5% florasulam, the chlorine of 30%2 first 4,5% alkyl naphthalene formaldehyde condensation product sulfoacid calcium, 6% alkyl phenol is weighed to gather Oxyethylene group ether sulfonic acid sodium, 2% Negel, 4% attapulgite, fine particle calcium carbonate add to 100% parts by weight.Above-mentioned raw materials are blended, The chlorine wettable powder of 45% pyraflufen-ethyl florasulam, 2 first 4 is made after air-flow crushing.

Example of formulations 2

Weigh 20% pyraflufen-ethyl, 6% florasulam, the chlorine of 20%2 first 4,7% sodium lignin sulfonate, 5% AEO phosphorus Acid esters, 8% sodium lignin sulfonate, 3% sodium alkyl sulfate, 4% White Carbon black, kaolin add to 100% parts by weight.Above-mentioned raw materials are through mixed Close, the different monooctyl ester wettable powder of chlorine of 46% pyraflufen-ethyl florasulam, 2 first 4 is made after air-flow crushing.

Example of formulations 3

Weigh 15% pyraflufen-ethyl, 10% florasulam, the chlorine of 25%2 first 4,8% Negel, 6% sodium lignin sulfonate, 3% 2 Sodium butylnaphthalenesulfonate, 3% sodium naphthalene sulfonate, 4% sodium carboxymethylcellulose, 5% sodium sulphate, fine particle calcium carbonate add to 100% parts by weight.Above-mentioned raw materials The method i.e. mixing of frequent regulation water intaking dispersible granule, ultra micro air-flow crushing, mixing, granulation step produce 50% pyraflufen-ethyl pair The chlorine water dispersible granule of 2 first of penoxsulam 4.

Example of formulations 4

Weigh 10% pyraflufen-ethyl, 4% florasulam, the chlorine of 30%2 first 4,8% polycarboxylate T36,4% lauryl sodium sulfate, 2% alkane Base sodium sulfonate, 5% polyvinyl alcohol, attapulgite add to 100% parts by weight.The method of the frequent regulation water intaking dispersible granule of above-mentioned raw materials I.e. mixing, ultra micro air-flow crushing, mixing, granulation step produce the different monooctyl ester moisture of the chlorine of 44% pyraflufen-ethyl florasulam, 2 first 4 Shot agent.

Example of formulations 5

Weigh 5% pyraflufen-ethyl, 2% florasulam, the chlorine of 15%2 first 4,6% sodium alkyl sulfate, 3% alkylphenol-formaldehyde resin polyoxyethylene Ether, 0.5% methylcellulose, 4% propane diols, 0.5% potassium sorbate, 0.4% butanol, deionized water add to 100% parts by weight.It is above-mentioned Raw material is blended, and high speed shear disperses 30min, and the chlorine of 22% pyraflufen-ethyl florasulam, 2 first 4 is made after being sanded with sand mill Suspending agent.

Example of formulations 6

10% pyraflufen-ethyl, 8% florasulam, the chlorine of 10%2 first 4,5% alkylpolyoxyethylene phosphate, 2% alkyl is weighed to gather Oxygen vinethene sodium sulfonate, 0.5% bentonite, 0.4% carboxyethyl cellulose, 4% benzoic acid, 0.5% sodium benzoate, 0.5% silicone oil, go Ionized water adds to 100% parts by weight.Above-mentioned raw materials are blended, and high speed shear disperses 30min, and 28% pyrrole is made after being sanded with sand mill The different monooctyl ester suspending agent of the careless chlorine of 2 first of ether florasulam 4.

Example of formulations 7

Weigh 8% pyraflufen-ethyl, 7% florasulam, the chlorine of 20%2 first 4,6% polycarboxylic acids sodium, 5% Tween-60 #, 5% agriculture breast 2201,2% alkane Base sodium sulphate, 0.5% white carbon, 6% propane diols, rapeseed oil add to 100% parts by weight.Above-mentioned raw materials are blended, and high speed shear is disperseed 30min, the dispersible oil-suspending agent of chlorine of 35% pyraflufen-ethyl florasulam, 2 first 4 is made after being sanded with sand mill.

Example of formulations 8

Weigh 6% pyraflufen-ethyl, 4% florasulam, the chlorine of 14%2 first 4,5% sodium lignin sulfonate, 6% this disk -60#, 8% Nongru-700 #, 1% sodium naphthalene sulfonate, 0.5% aluminium-magnesium silicate, 4% urea, soybean oil add to 100% parts by weight.Above-mentioned raw materials are blended, high speed shear point 30min is dissipated, the dispersible oil-suspending agent of 24% pyraflufen-ethyl florasulam, the 2 first different monooctyl ester of 4 chlorine is made after being sanded with sand mill.

Example of formulations 9

Weigh 14% pyraflufen-ethyl, 6% florasulam, the chlorine of 12%2 first 4,6% agriculture breast 1601#, 5% agriculture breast 400#, 15% dimethylbenzene, 4% Dimethylbenzene, 5% n-butanol, through dissolving completely and being well mixed, deionized water adds to 100% parts by weight, and 32% pyrrole grass is made after stirring The chlorine microemulsion of 2 first of ether florasulam 4.

Example of formulations 10

Weigh 18% pyraflufen-ethyl, 2% florasulam, the chlorine of 16%2 first 4,5% Nongru-700 #, 6% polysorbate60-#, 12% toluene, 6% positive fourth Alcohol, through dissolving completely and being well mixed, deionized water adds to 100% parts by weight, and the double fluorine sulphur grass of 36% pyraflufen-ethyl are made after stirring The different monooctyl ester microemulsion of the chlorine of 2 first of amine 4.

Example of formulations 11

Weigh 12% pyraflufen-ethyl, 4% florasulam, the chlorine of 18%2 first 4,5% agriculture breast 600#, 5% Negel, 6% benzoic acid first Ester, 5% glycerine, 0.5% hexanol, 1% polyvinyl alcohol, deionized water add to 100% parts by weight.Above-mentioned raw materials mix by high speed shear Uniformly, ball milling 2~3 hours in ball mill, make diameter of particle all below 5 μm, that is, the double fluorine sulphur grass of 34% pyraflufen-ethyl are made The chlorine suspension emulsion of 2 first of amine 4.

Example of formulations 12

Weigh 16% pyraflufen-ethyl, 1% florasulam, the chlorine of 13%2 first 4,4% Nongru-700 #, 4% polycarboxylic acids sodium, 5% ethyl acetate, 2.5% propane diols, 1.5% octanol, 1% bentonite, deionized water add to 100% parts by weight.Above-mentioned raw materials mix by high speed shear Uniformly, ball milling 2~3 hours in ball mill, make diameter of particle all below 5 μm, that is, the double fluorine sulphur grass of 30% pyraflufen-ethyl are made The different monooctyl ester suspension emulsion of the chlorine of 2 first of amine 4.

Biological Examples 1：Prevent and treat wheat weedses broad-leaved field control effectiveness test.

Inventor has carried out example of formulations 1 in 2016 in Xiuqian City of Jiangsu Province Sihong（The double fluorine sulphur grass of 45% pyraflufen-ethyl The chlorine wettable powder of 2 first of amine 4）, example of formulations 4（The different monooctyl ester water-dispersible grain of the chlorine of 44% pyraflufen-ethyl florasulam, 2 first 4 Agent）, example of formulations 5（The chlorine suspending agent of 22% pyraflufen-ethyl florasulam, 2 first 4）, example of formulations 8（24% pyraflufen-ethyl The dispersible oil-suspending agent of 2 first of the florasulam different monooctyl ester of 4 chlorine）, example of formulations 9（32% pyraflufen-ethyl florasulam 2 The chlorine microemulsion of first 4）, example of formulations 12（The different monooctyl ester suspension emulsion of the chlorine of 30% pyraflufen-ethyl florasulam, 2 first 4）Prevent and treat wheatland Weeds field control effectiveness test, demonstrate prevention effect of the medicament to wheatland broad leaved weed and the security to wheat.

Trial crops are wheat, and controlling object is wheatland broad leaved weed, the leaf phase dispenser of weeds 3~5.Experimental plot physical features is put down Smooth, soil is loam, middle fertility, pH value 7.2.Test medicine and dosage refer to table 11.Blank control separately is set, is often handled 4 times Repeat, per the ㎡ of cell 30, totally 52 cells, the random district's groups of cell arrange.Using conventional spray-on process, mu dispenser liquid 45kg.

Table 11 prevents and treats wheat weedses field control effectiveness test result

Table of field test results is bright, and above example of formulations has good prevention effect to wheatland broad leaved weed, and active ingredient is used Dose is sprayed 1 time by 500g/ hectares, reaches more than 95% to the average preventive effect of 30 days after wheat weedses medicine, hence it is evident that better than each The preventive effect of comparison medicament.By to 30 days significance difference analysis after medicine, pyraflufen-ethyl, florasulam and the chlorine of 2 first 4 or the chlorine of 2 first 4 Different monooctyl ester combination is notable with other control treatment preventive effect othernesses.

Security survey：Observed during experiment, wheat growth safety, no poisoning phenomenon occur all reagent agents.

In summary, composition of the invention is to use three kinds of active component compound schemes, and its activity and herbicidal effect are not It is the simple superposition of each component activity, compared with existing unitary agent or binary built preparation, there is significant herbicidal effect, Synergistic effect is notable, can be with delaying drug resistance, and security is good, meets the security requirement of pesticidal preparations.

Claims (5)

1. A kind of 1. ternary weeding composition containing pyraflufen-ethyl, it is characterised in that：Active component is by pyraflufen-ethyl, florasulam and 2 Chlorine of first 4 or derivatives thereof forms, and the percentage by weight that pyraflufen-ethyl accounts for the composition is 1%~10%, and florasulam accounts for described The percentage by weight of composition be the percentage by weight that chlorine of 0.1~10%, 2 first 4 or derivatives thereof accounts for the composition be 10~ 50%。
2. 2. the ternary weeding composition containing pyraflufen-ethyl according to claim 1, it is characterised in that：The chlorine derivative of 2 first 4 is selected from 2- Methyl -4- chlorobenzene benzene oxygen isopropyl acid (the also known as chlorine isopropyl acid of 2 first 4), 2- methyl -4- chlorobenzenes phenoxy butyric acid (the also known as neoprene of 2 first 4 Acid), 2- methyl -4- chlorobenzene phenoxy butyric acids butyl ester (also known as Thistrol butyl ester), the different monooctyl ester of the chlorine of 2 first 4, the chloroethene thioester of 2 first 4,2 The thio second fat of the chlorine of first 4, the chlorine sodium salt of 2 first 4, the chlorine sylvite of 2 first 4 or the chlorine isopropyl amine salt of 2 first 4.
3. 3. the ternary weeding composition containing pyraflufen-ethyl according to claim 1, it is characterised in that：The combination dosage form is can WP, water dispersible granules, suspending agent, dispersible oil-suspending agent, microemulsion, suspension emulsion.
4. 4. purposes of the ternary weeding composition containing pyraflufen-ethyl on preventing and treating wheatland broad leaved weed according to claim 1.
5. 5. purposes according to claim 3, wheat weedses include broad leaved weed be clearvers, Veronica, chickweed, Descurainia sophia and Shepherd's purse.