CN107574215A - A kind of preparation method of pollen pini active peptide - Google Patents
A kind of preparation method of pollen pini active peptide Download PDFInfo
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Abstract
Denomination of invention：A kind of preparation method summary of pollen pini active peptide：The present invention relates to traditional Chinese medicine and technical field of biology.It is formed using the pollen pini of fresh dried as raw material through ultramicro grinding, homogenate, enzymolysis, centrifugation, sterilizing.Pollen pini after ultramicro grinding is homogenized adjusts pH value 36, adds cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme is digested, and every gram of pollen pini adds 5,000 10000 enzyme-activity units（u）, 50 60 degrees Celsius of temperature control enzymolysis 36 hours；Then through enzyme deactivation, centrifugation, sterilize to obtain pollen pini active peptide liquid；Freeze-dried powder product, oral liquid product, capsule product can be prepared.The pollen pini active peptide has the pharmacological activity such as anti arteriosclerosis, reducing blood lipid and cholesterol, analgesia, radioresistance, preventing and treating diabetes, strengthen immunity, cancer-resisting.Process scientific and precise of the present invention, strong operability, is easy to industrialized production.
Description
Technical field
The present invention relates to traditional Chinese medicine and technical field of biology.It is especially a kind of with pollen pini prepare pollen pini active peptide and
Its preparation method.
Background technology
Pollen pini is the flower of the Chinese native seeds-- masson pine and Chinese pine that are grown in 1100-1500 meters of mountain areas of height above sea level
Powder, compared with the pollen of honeybee source, pollen pini is artificial collection, with flower source is single, quality is pure, ingredient stability, non agricultural chemical residuum
Thing, the features such as without zoohormone.The more other any plant pollen mouthfeels of pollen pini are good, feel there is light perfume (or spice) when taking
Taste.Ancients claim：" gas of pine and cypress can make one long-lived！" so pollen pini can be rated as " king of pollen ".Through scientific research and it was verified that length
Phase, which takes, to have no toxic side effect.Pollen pini is the spermatid of pine tree pistil, is responsible for the important task of pine tree procreation, includes more than 200 kind battalion
Part is formed, and it is reasonable to arrange in pairs or groups, and can supplement comprehensively, the nutrition needed for balancing human body.Its health-care effect is big, and conditioning scope is wide, is
Qualified " healthy bodyguard ".Thus, all ages and classes, the user of different constitutions can in the short period of time, in difference
Good effect is received in degree.The Chinese《Sheng Nong's herbal classic》It is nontoxic to record pollen pini gas sweet taste, cures mainly trusted subordinate's fever and chills perverse trend,
Diuresis, disappear extravasated blood, and long term usage is made light of one's life by commiting suicide benefiting energy, macrobiosis.Tang《Tang materia medica》Preserved egg is that pine is yellow, strokes and takes just like cattail pollen, long term usage
Order is made light of one's life by commiting suicide, and is treated disease and is surpassed skin, leaf and fat.Pollen pini contains a variety of nutriments, including 22 kinds of amino acid, 14 kinds of vitamins and 30
Various trace elements and substantial amounts of active protease, core, flavone compound and other active materials.The egg that pollen pini is rich in
White matter is more to be existed in the form of free amino acid, content exceed milk, 5-7 times of egg；Ascorbic content is higher than fresh water
Fruit and vegetables, it is referred to as the king of natural complex.Pollen pini is taken, can be lessened fatigue in a short time, enhancing muscle power;Constipation disappears,
Digestion takes a turn for the better；Skin is fine and smooth, has rosy cheeks；Sleep is steady and sure, is in a cheerful frame of mind；Energetic, memory improves.
Pollen pini contains abundant amino acid and all natural vitamin and a variety of enzymes, can strengthen skin metabolism, increase
Skin elasticity, delay skin aging.Injection Vitamin B_6 and B family vitamin coordinative role, can activating cell, remove free radical, resistance
The generation of disconnected chloasma, butterfly macules, eliminates dermal melanin, reduces, removes whelk so that the pure white beauty of skin；It is meanwhile right
Brighten the hair healthy hair also has preferable effect.Pollen pini suffers from good therapeutic action to skin disease.The pollen pini of non-broken wall has very strong
Water imbibition, can eliminating dampness astringing to arrest bleeding, external application can wind-dispelling hemostasis, refreshing body anti-inflammatory, it is non-stimulated to skin, without side effects such as allergy；
To eczema, impetigo, skin erosion, concentrated water be dripping, traumatism and bleeding, diaper dermatitis etc. have good therapeutic action.Especially use
In the refreshing body of infant skin care, children's skin eczema is prevented and treated, curative effect is good, quick.Pollen pini preventing and treating the elderly pruitus is treated
Effect is notable, can also prevent and treat bedsore.Trace element, flavonoids, arginine, injection Vitamin B_6, carrotene and selenium etc. contained by pollen pini,
Have and remove interior free yl effect, body antioxidant reductase can be improved（Such as copper-zinc superoxide dismutase）Activity, suppression
Peroxidatic reaction of lipid processed, eliminate senile plaque expelling, delaying cell aging.Pollen pini makes one to also reside in the reason for rejuvenation, and it is more
The active nutritional matter interaction of sample, whole body function is adjusted, keeps body tissue youthful vigor, make intelligence is intelligent not wane,
So as to anti-aging, increase the life-span.Pollen pini can directly supplement the nutrients, and can also be absorbed by improving digestive function from food
Nutrition, energy is supplemented for body, increases endurance, is allowed to indefatigability.Pollen pini can also adjust nervous system, alleviate spirit and work
Make pressure, caused by releasing various burdens and the elderly fatiguability.Pollen pini can reduce internal lactate level, be adapted to add
The labor intensity such as class worker, students preparing for examination, pre-games sportsman are big, mental labour severe one is taken.Pollen pini nutrient balance, fiber-rich
And it is low in calories, 72.5% is unrighted acid in institute's fatty acids, with vitamin E act synergistically, can bidirectional modulation human body courage consolidate
Alcohol, harden muscles, figure it is well-balanced.Content of cellulose in pollen pini is up to 29%, on the one hand it can produce satiety, reduces
Food intake, avoid overnutrition；On the one hand suppress and delay cholesterol being drenched with triglycerides in fat metabolic process again
The absorption of Palestine and China；Meanwhile cellulose can promote function of intestinal canal, accelerate excrement excretion, PLA General Hospital is carried out with German cooperation
Research and experiment confirm that pollen pini makes in excrement Cholesterol Excretion amount increase by 0.8 times, and triglyceride excretion increases by 2 times, from
More than ten kind aliphatic acid excretion at most increases about 7 times of the carbon 12 to carbon 22.Lecithin in pollen pini also accelerates body fat
Burning, its diuretic property also contribute to lose weight.Cardiovascular and cerebrovascular disease is that HypercholesterolemicRats are unbalance, blood fat and cholesterol level
Caused by too high.Pollen pini nutrient balance, fiber-rich and it is low in calories, 72.5% is unrighted acid in institute's fatty acids, with dimension give birth to
Plain E synergies, can bidirectional modulation body's cholesterol.On the one hand 29% cellulose is up in pollen pini can reduce food intake,
On the one hand suppress and delay again the absorption of cholesterol and triglycerides；Meanwhile pollen pini accelerates excrement excretion again, by superabundant fats
Excrete, the research and experiment that PLA General Hospital is carried out with German cooperation confirms that pollen pini makes Cholesterol Excretion in excrement
0.8 times of amount increase, triglyceride excretion increases by 2 times, from carbon 12 to the at most increase of more than the ten of carbon 22 kind aliphatic acid excretions about
7 times.
Pollen pini is rich in several amino acids needed by human, vitamin, trace element, enzyme, flavonoids, nucleic acid, insatiable hunger
With nutritional ingredient and the bioactive substance such as aliphatic acid.Being tested through function assessment proves, pollen pini has immunoregulatory health care work(
Can, immunity of organisms can be strengthened.Pollen pini effect is mainly reflected in the micronutrient that can be supplemented in ordinary meal with effect
Deficiency, promote the metabolism of human body, adjust the physiology of human body：Digestive system：Strengthen digestive function, whet the appetite, adjust intestines
Stomach function, overcome constipation or diarrhoea, prevent colon cancer；The function of detoxification that liver can also be improved promotes growth of liver cell etc..
The circulatory system：Prevent anaemia.Strengthen the elasticity of vascular wall, prevention of arterial hardening；Improve microcirculation, strengthen the intensity of vascular wall,
Steady blood pressure, prevent angiorrbagia etc..Internal system：Diabetes and prostatic disorders are nursed one's health, are had to prostate cancer well
Prevention and adjustment effect.Nervous system：Nervous headache, insomnia.Pollen pini has the effect of double recuperation：Blood pressure is high and low double
To conditioning；Diarrhoea, constipation double recuperation；Fat, double recuperation of becoming thin.
As the pollen pini of plant essence, before more than 2000 years, just recognized and utilized by our ancestors.Pollen pini is plant
Sperm, it breeds life, and nutrition is most abundant, is the clean potato in plant.But pollen pini is, tool molecular by spore
There is one layer of acidproof, alkaline-resisting, corrosion resistant hard chitin outer wall, what this just have impact on active ingredient fully absorbs utilization, at present
In the world also without the breaking trachytectum technology in complete meaning, because chitinase does not have industrialized production also.Present market has
Simply mechanical breaking-wall method or wind-tunnel broken wall pollen pini product, hard spore coat is smashed, this also simply promotes to absorb,
The effect of pollen pini disease preventing and treating function can not fundamentally be given full play to.
Active peptide is the general name of more than 1,000 kinds of peptide.It grows people's, metabolism, disease and aging, dead
During play key effect.Active peptide is most important active material in human body.Exactly because its secretory volume in vivo
Increase or reduce, the mankind is had childhood, in childhood, adult is old until the cycle of death.And take active peptide and just break
This cycle of life, so as to reach extending life, the miraculous effects of effective delaying senility.Peptide in vivo as carrier and
Means of transport, by the nutrient delivery that people are eaten usually to each position of human body, give full play to its function；Peptide is made in vivo
For neurotransmitter, transmission information；Peptide has extremely strong activity and diversity, fully adjustable human body physiological function, strengthens human body
Physiologically active；Peptide can not only provide the nutriment needed for growth in humans's development, and have special biological function, can prevent
Control thrombus, high fat of blood, hypertension, anti-aging is antifatigue, improve immunity of organisms, promote human body to protein, vitamin,
A variety of absorptions to human body healthy trace elements with household such as amino acid, calcium, iron, zinc, selenium, magnesium, copper；Some small peptides have former food protein
Matter or other composition unexistent important physiological functions of amino acid.The less small peptide of some molecular weight in biologically active peptide, with
Amino acid transport function phase ratio, the small peptide in biologically active peptide, which has, absorbs quick, low consumption and undersaturated feature.Therefore how
Pollen pini is made into function and absorbs more preferable active peptide, preferably reaches the purpose that traditional Chinese medicine preventives treatment of disease, really realizes Chinese medicine
Modernization, it has also become traditional Chinese medicine and technical field of biology problem urgently to be resolved hurrily.
The content of the invention
In order to overcome the wastage of material and absorption of human body utilization rate in pollen pini active material extraction process in the prior art
Low deficiency, the invention provides a kind of preparation method of pollen pini active peptide, bioactivity is rich in the pollen pini active peptide
Peptide, there is anti arteriosclerosis, reducing blood lipid and cholesterol, analgesia, radioresistance, preventing and treating diabetes, strengthen immunity, cancer-resisting etc.
Pharmacological activity, and be easy to digest and assimilate, nutritious body utilization rate is high.The preparation method work of the lucidum spore powder active peptide
Skill is rigorous reasonable, workable, it is easy to accomplish industrialized production.
The purpose of the present invention is achieved through the following technical solutions：A kind of preparation method of pollen pini active peptide, it is special
Different part is：
1st, the preparation of pollen pini active peptide：Choose drying pollen pini fresh then and carry out ultramicro grinding processing；Add Ultramicro-powder
The water of broken 10-15 times of pollen pini weight is diluted immersion and stirred for 30 minutes, crushes the pollen pini after homogenate and adjusts pH value 3-
6, add cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme is digested, and enzyme dosage is every
Gram pollen pini adds 5000-10000 enzyme-activity unit（u）, between 50-60 degrees Celsius of temperature control, digest 3-6 hours；Enzymolysis
Centrifugation, centrifuge speed 4000-10000rpm or so are cooled down after finishing boiling water heating bath enzyme deactivation 10-20 minutes, produces peptide pollen pini
Active liquid；
2nd, the pollen pini active peptide liquid of above-mentioned preparation is put into stainless steel cask enter steam sterilization cabinet between 100-120 degree Celsius and steam
Vapour autoclaving 15-40 minutes；
3rd, the pollen pini active peptide liquid of above-mentioned preparation is done to freeze dryer vacuum refrigeration on cillin bottle by lyophilized technique specification is filling
It is dry, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；Pure water is added to press the pollen pini active peptide liquid of above-mentioned preparation
Oral liquid process specification is filling to oral liquid bottle, produces pollen pini oral liquid of active peptide product of the present invention；By above-mentioned preparation
Pollen pini active peptide liquid it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacturing techniques specification it is canned into
Capsule, produce pollen pini active peptide capsule product of the present invention.
The present invention select Reishi sporule powder raw material, and a large amount of active peptide components are generated by controlled enzymatic hydrolysis, its nutritive value with
Absorption rate and edible safety greatly improve, anti arteriosclerosis, reducing blood lipid and cholesterol, bidirectional modulation blood pressure, anti-spoke
Penetrate, prevent and treat diabetes, strengthen immunity, the preventing and treating pharmacological activity such as prostatic disorders and also accordingly strengthen, a kind of pollen pini of the present invention
Active peptide and preparation method thereof is freeze-dried into bottled freeze-dried powder product according to freeze dryer on the filling lyophilized bottle of lyophilized technique specification,
The additive-free preservative of vacuum freeze drying, safe, long shelf-life；It plus pure water are according to oral liquid process specification
It is filling into oral liquid product, color is natural, distinctive natural flavour mountaineous good mouthfeel；By the spray drying or cold of pollen pini active peptide liquid
It is lyophilized it is dry be prepared into powdery granule, it is filling into capsule product by capsule manufacturing techniques specification, take easy to carry.Present invention system
Standby technique is rigorous rationally, strong operability, is especially suitable for large-scale production.
Embodiment
With reference to embodiment, the present invention will be further described
Embodiment one, 1, the preparation of pollen pini active peptide liquid：Choose drying pollen pini 20kg fresh then and carry out ultramicro grinding
Processing；The water of 10 times of addition ultramicro grinding pollen pini weight is diluted immersion and stirred for 30 minutes, crushes the pine after homogenate
Pollen adjusts pH value 6, adds cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme is digested,
Enzyme dosage is that every gram of pollen pini adds 9500 enzyme-activity units（u）, 50 degrees Celsius of temperature control, digest 4.5 hours；Enzymolysis finishes
Boiling water heating bath enzyme deactivation cools down centrifugation, centrifuge speed 9000rpm or so after 10 minutes, produces pollen pini active peptide liquid；
2nd, the pollen pini active peptide liquid of above-mentioned preparation is put into stainless steel cask enter steam sterilization cabinet and gone out in 100° centigrade vapor injection
Bacterium 40 minutes；
3rd, the pollen pini active peptide liquid of above-mentioned preparation is done to freeze dryer vacuum refrigeration on cillin bottle by lyophilized technique specification is filling
It is dry, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；Pure water is added to press the pollen pini active peptide liquid of above-mentioned preparation
Oral liquid process specification is filling to oral liquid bottle, produces pollen pini oral liquid of active peptide product of the present invention；By above-mentioned preparation
Pollen pini active peptide liquid it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacturing techniques specification it is canned into
Capsule, produce pollen pini active peptide capsule product of the present invention.
Embodiment two, 1, the preparation of pollen pini active peptide liquid：Choose drying pollen pini 25kg fresh then and carry out ultra micro
Pulverization process；The water of 9 times of addition ultramicro grinding pollen pini weight is diluted immersion and stirred for 30 minutes, after crushing homogenate
Pollen pini adjusts pH value 4, adds cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme carries out enzyme
Solution, enzyme dosage are that every gram of lucidum spore powder adds 10000 enzyme-activity units（u）, 55 degrees Celsius of temperature control, digest 6 hours；Enzyme
Solution cools down centrifugation, centrifuge speed 8000rpm or so after finishing boiling water heating bath enzyme deactivation 15 minutes, produces pollen pini active peptide liquid,
2nd, the pollen pini active peptide liquid of above-mentioned preparation is put into stainless steel cask enter steam sterilization cabinet and gone out in 105 degree of vapor injections Celsius
Bacterium 30 minutes；
3rd, the pollen pini active peptide liquid of above-mentioned preparation is done to freeze dryer vacuum refrigeration on cillin bottle by lyophilized technique specification is filling
It is dry, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；Pure water is added to press the pollen pini active peptide liquid of above-mentioned preparation
Oral liquid process specification is filling to oral liquid bottle, produces pollen pini oral liquid of active peptide product of the present invention；By above-mentioned preparation
Pollen pini active peptide liquid it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacturing techniques specification it is canned into
Capsule, produce pollen pini active peptide capsule product of the present invention.
Embodiment three, 1, the preparation of pollen pini active peptide liquid：The net pollen pini 15kg of drying fresh then is chosen to be surpassed
Crushing of Ultrafine processing；The water of 15 times of addition ultramicro grinding pollen pini weight is diluted immersion and stirred for 30 minutes, crushes homogenate
Pollen pini afterwards adjusts pH value 4.5, adds cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme
Digested, enzyme dosage is that every gram of pollen pini adds 8000 enzyme-activity units（u）, 58 degrees Celsius of temperature control, it is small to digest 4.5
When；Enzymolysis cools down centrifugation, centrifuge speed 6000rpm or so after finishing boiling water heating bath enzyme deactivation 12 minutes, produces pollen pini activity
Peptide liquid,
2nd, the pollen pini active peptide liquid of above-mentioned preparation is put into stainless steel cask enter steam sterilization cabinet and gone out in 115 degree of vapor injections Celsius
Bacterium 25 minutes；
3rd, the pollen pini active peptide liquid of above-mentioned preparation is done to freeze dryer vacuum refrigeration on cillin bottle by lyophilized technique specification is filling
It is dry, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；Pure water is added to press the pollen pini active peptide liquid of above-mentioned preparation
Oral liquid process specification is filling to oral liquid bottle, produces pollen pini oral liquid of active peptide product of the present invention；By above-mentioned preparation
Pollen pini active peptide liquid it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacturing techniques specification it is canned into
Capsule, produce pollen pini active peptide capsule product of the present invention.
Example IV, 1, the preparation of pollen pini active peptide liquid：The net pollen pini 18kg of drying fresh then is chosen to be surpassed
Crushing of Ultrafine processing；The water of 14 times of addition ultramicro grinding pollen pini weight is diluted immersion and stirred for 30 minutes, crushes homogenate
Pollen pini afterwards adjusts pH value 5, adds cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme enters
Row enzymolysis, enzyme dosage are that every gram of pollen pini adds 8500 enzyme-activity units（u）, 56 degrees Celsius of temperature control, digest 3 hours；Enzyme
Solution cools down centrifugation, centrifuge speed 5000rpm or so after finishing boiling water heating bath enzyme deactivation 13 minutes, produces pollen pini active peptide liquid,
2nd, the pollen pini active peptide liquid of above-mentioned preparation is put into stainless steel cask enter steam sterilization cabinet and gone out in 120 degree of vapor injections Celsius
Bacterium 15 minutes；
3rd, the pollen pini active peptide liquid of above-mentioned preparation is done to freeze dryer vacuum refrigeration on cillin bottle by lyophilized technique specification is filling
It is dry, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；Pure water is added to press the pollen pini active peptide liquid of above-mentioned preparation
Oral liquid process specification is filling to oral liquid bottle, produces pollen pini oral liquid of active peptide product of the present invention；By above-mentioned preparation
Pollen pini active peptide liquid it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacturing techniques specification it is canned into
Capsule, produce pollen pini active peptide capsule product of the present invention.
A kind of pollen pini active peptide prepared by the present invention freezes active peptide liquid according to the filling lyophilized bottle of lyophilized technique specification
Dry machine is freeze-dried into bottled freeze-dried powder product, the additive-free preservative of vacuum freeze drying, safe, long shelf-life；Add
Add pure water filling into oral liquid product according to oral liquid process specification, color is natural, and distinctive natural flavour mountaineous mouthfeel is good
It is good；Active peptide liquid is spray-dried or is freeze-dried and is prepared into powdery granule, it is filling into capsule by capsule manufacturing techniques specification
Product, take easy to carry.Present invention composition takes Traditional Chinese Medicine formula and rigorous Chinese medicine preparation specification, with modern biotechnology skill
The advanced processing technology of art is prepared, and its process scientific and precise is reasonable, strong operability, is especially suitable for large-scale production.
Claims (3)
1. a kind of pollen pini active peptide and preparation method thereof, it is characterised in that by the following steps：
（1）, pollen pini active peptide preparation：Choose drying pollen pini fresh then and carry out ultramicro grinding processing；Add ultra micro
The water of 10-15 times of crushing pollen pini weight is diluted immersion and stirred for 30 minutes, crushes the pollen pini after homogenate and adjusts pH value
3-6, add cellulase, edible mushroom enzyme, neutral proteinase, papain（1:1:1:2）Multienzyme is digested, and enzyme dosage is
Every gram of pollen pini adds 5000-10000 enzyme-activity unit（u）, between 50-60 degrees Celsius of temperature control, digest 3-6 hours；Enzyme
Solution cools down centrifugation, centrifuge speed 4000-10000rpm or so after finishing boiling water heating bath enzyme deactivation 10-20 minutes, produces pollen pini
Active peptide liquid；
（2）, pollen pini active peptide liquid prepared by above-mentioned steps (1) put stainless steel cask and enters steam sterilization cabinet in 100-120 Celsius
Steam high-voltage sterilizing 15-40 minutes between degree；
（3）, by above-mentioned steps (1),（2）The pollen pini active peptide liquid of preparation is filling to lyophilized on cillin bottle by lyophilized technique specification
Machine vacuum freeze drying, produce the bottled freeze-dried powder product of pollen pini active peptide of the present invention；By the pollen pini active peptide of above-mentioned preparation
Liquid adds pure water filling to oral liquid bottle by oral liquid process specification, produces pollen pini oral liquid of active peptide production of the present invention
Product；By the pollen pini active peptide liquid of above-mentioned preparation it is freeze-dried or spray drying be prepared into powdery granule, by capsule manufacture
Technological specification is canned into capsule, produces pollen pini active peptide capsule product of the present invention.
2. a kind of pollen pini active peptide according to claim 1 and preparation method thereof, it is characterized in that：Described pine
Pollen active peptide liquid is filling to freeze dryer vacuum freeze drying on cillin bottle by lyophilized technique specification, produces pollen pini of the present invention and lives
The property bottled freeze-dried powder product of peptide；Add pure water filling by oral liquid process specification the pollen pini active peptide liquid of above-mentioned preparation
To oral liquid bottle, pollen pini oral liquid of active peptide product of the present invention is produced；The pollen pini active peptide liquid of above-mentioned preparation is chilled
Dry or spray drying is prepared into powdery granule, it is canned into capsule by capsule manufacturing techniques specification, produce pollen pini of the present invention
Active peptide capsule product.
3. a kind of pollen pini active peptide according to claim (1) and preparation method thereof, it is characterized in that：Described
Four kinds of enzymes of cellulase, edible mushroom enzyme, neutral proteinase, papain of pollen pini are digested, it is 1 that it, which forms weight ratio,：1：
1：2.
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| CN201710611722.4A CN107574215A (en) | 2017-07-25 | 2017-07-25 | A kind of preparation method of pollen pini active peptide |
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Cited By (3)
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| CN109694895A (en) * | 2019-03-06 | 2019-04-30 | 河北神顺健康科技有限公司 | Preserved egg active peptide, the composition comprising it, agaric slice and its preparation process |
| CN110229865A (en) * | 2019-07-11 | 2019-09-13 | 云南惠本生物工程有限公司 | A kind of pollen pini active peptide extracting method |
| CN111621538A (en) * | 2020-06-22 | 2020-09-04 | 浙江亚林生物科技股份有限公司 | Preparation method and application of pollen pini oligopeptide |
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| CN101100691A (en) * | 2007-07-13 | 2008-01-09 | 承德畅达天然营养品有限公司 | Method for extracting small peptides from pine pollen by using enzyme |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109694895A (en) * | 2019-03-06 | 2019-04-30 | 河北神顺健康科技有限公司 | Preserved egg active peptide, the composition comprising it, agaric slice and its preparation process |
| CN110229865A (en) * | 2019-07-11 | 2019-09-13 | 云南惠本生物工程有限公司 | A kind of pollen pini active peptide extracting method |
| CN111621538A (en) * | 2020-06-22 | 2020-09-04 | 浙江亚林生物科技股份有限公司 | Preparation method and application of pollen pini oligopeptide |
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