CN107397901A - A kind of Chinese medicine composition for treating insomnia and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating insomnia and preparation method thereof Download PDF

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CN107397901A
CN107397901A CN201710630017.9A CN201710630017A CN107397901A CN 107397901 A CN107397901 A CN 107397901A CN 201710630017 A CN201710630017 A CN 201710630017A CN 107397901 A CN107397901 A CN 107397901A
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chinese
chinese medicine
medicine composition
fruit
insomnia
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罗兴贵
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Sichuan Xingjujiao Medical Technology Co Ltd
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Sichuan Xingjujiao Medical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of Chinese medicine composition for treating insomnia provided according to the understanding mechanism of traditional Chinese medicine in treating insomnia, each component and its mass parts ratio of the Chinese medicine composition are as follows:9~16g of husked sorghum, 15~28g of Poria cocos, 10~26g of spina date seed, 5~16g of radix scutellariae, 10~26g of the fruit of Chinese wolfberry, 8~16g of the red sage root, 6~16g of lily, 3~16g of the fruit of Chinese magnoliavine, 10~26g of Polygonum multiflower knotweed, 3~6g of the coptis, 10~25g of the tuber of dwarf lilyturf, 8~16g of Radix Angelicae Sinensis, 3~12g of polygala, 3~12g of radix glycyrrhizae;Medicine provided by the invention is a Chinese prescription treated both principal and secondary aspect of disease.

Description

A kind of Chinese medicine composition for treating insomnia and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition for treating insomnia, particularly for insomnia The field of the Chinese medicine composition that patient uses and preparation method thereof.
Background technology
Doctor thinks:There is limitation in present clinical medicine science, still, Therapist are to the understanding of insomnia Start according to clinical research, be defined to insomnia, neurology branch of Chinese Medical Association sleep-disorder group in 2012 according to Existing evidence-based medical, formulate《Chinese Adult insomnia Clinics and Practices guide》, wherein insomnia refers to patient to sleep Time and(Or)Quality is unsatisfactory for and influences a kind of subjective experience of social function in the daytime.
So, a kind of Chinese medicine composition that can effectively treat insomnia how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment insomnia, people gradually appreciate Chinese traditional treatment mistake The advantages of dormancy, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for the insomnia of existing western medical treatment Present situation, the purpose of the present invention are to be to provide a kind of Chinese medicine composition for treating insomnia, recover strong early to solve insomniac The problem of health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be treated State insomnia.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:A kind of Chinese medicine for treating insomnia is provided Composition and preparation method thereof, it is characterised in that each component and its mass parts of the Chinese medicine composition are than as follows:
9~16g of husked sorghum, 15~28g of Poria cocos, 10~26g of spina date seed, 5~16g of radix scutellariae, 10~26g of the fruit of Chinese wolfberry, 8~16g of the red sage root, 6~16g of lily, 3~16g of the fruit of Chinese magnoliavine, 10~26g of Polygonum multiflower knotweed, 3~6g of the coptis, 10~25g of the tuber of dwarf lilyturf, 8~16g of Radix Angelicae Sinensis, polygala 3 ~12g, 3~12g of radix glycyrrhizae.
A kind of Chinese medicine composition for treating insomnia and preparation method thereof, it is characterised in that the Chinese medicine composition it is each Component and its mass parts are than as follows:
10~14g of husked sorghum, 17~25g of Poria cocos, 11~23g of spina date seed, 6~14g of radix scutellariae, 11~23g of the fruit of Chinese wolfberry, the red sage root 9~ 14g, 7~14g of lily, 6~14g of the fruit of Chinese magnoliavine, 11~23g of Polygonum multiflower knotweed, 4~5.5g of the coptis, 12~22g of the tuber of dwarf lilyturf, Radix Angelicae Sinensis 10~ 14g, 6~11g of polygala, 5~11g of radix glycyrrhizae.
A kind of Chinese medicine composition for treating insomnia and preparation method thereof, it is characterised in that the Chinese medicine of " preferred plan " The each component and its mass parts of composition are than as follows:
Husked sorghum 12g, Poria cocos 22g, spina date seed 20g, radix scutellariae 12g, fruit of Chinese wolfberry 20g, red sage root 12g, lily 12g, fruit of Chinese magnoliavine 12g, night Hand over rattan 20g, coptis 5g, tuber of dwarf lilyturf 20g, Radix Angelicae Sinensis 12g, polygala 10g, radix glycyrrhizae 10g.
A kind of Chinese medicine composition for treating insomnia and preparation method thereof, it is characterised in that methods described comprises the following steps It is prepared:
A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped;
B, the raw material Chinese medicine wrapped is put into cold boiling water and soaks half an hour, then again by soaked medicine and immersion medicine The clarified solution of thing is put into marmite in the lump, and the cold boiling water for injecting medicine 60mm decoct 50 minutes for the first time, after leaching decoction, The tepor boiling water for re-injecting medicine 55mm carries out second of decoction 40 minutes, and secondary mixing is condensed into 50% milli of herb liquid 360 Rise standby.
A kind of Chinese medicine composition for treating insomnia and preparation method thereof, it is characterised in that the instructions of taking is:It will prepare Good herb liquid was taken with one day, morning and evening sub-service, milliliter/time of dosage 180, takes advantage of and warmly takes.Medication 15~21 days, symptom disappear, Disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Husked sorghum, nature and flavor:Sweet, cold nature, there is dispelling wind and eliminating dampness and stomach to calm the nerves, removing toxic substances sore the effect of, trembled with fear for treating malaria Heat, muscles and bones contraction urgency, dysentery, uneasy sleeping at night, pyogenic infections, dermatitis rhus, pernio, dog bite;
Poria cocos, nature and flavor:It is sweet, light, flat, have eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative the effect of, for treat difficult urination, Oedema turgor, phlegm and retained fluid cough are inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea;
Spina date seed, nature and flavor:It is sweet, flat, have nourishing the liver, calming heart, calm the nerves, arrest sweating the effect of, for treat restlessness of asrhenia type and insomnia, palpitation with fear it is seized with terror The diseases such as sad, polydipsia, abnormal sweating;
Radix scutellariae, nature and flavor:It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis;
The fruit of Chinese wolfberry, nature and flavor:It is sweet, mild-natured, have nourishing the liver, nourshing kidney, moistening lung the effect of, for treat caused by liver and kidney deficiency, have a dizzy spell, Visual one is clear, soreness and weakness of waist and knees, the expensive essence of impotence, cough due to consumptive disease, quenches one's thirst and draws drink;
The red sage root, nature and flavor:Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections;
Lily, nature and flavor:It is sweet, cold, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, for treating yin chronic cough, blood-stained sputum, void It is tired palpitation with fear, insomnia and dreamful sleep, absent-minded;
The fruit of Chinese magnoliavine, nature and flavor:It is sour, sweet, warm, there is the effect of restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming, for treating chronic diarrhea not Only, chronic cough and dyspnea of deficiency type, palpitaition, insomnia, dreaminess, spontaneous perspiration, night sweat, injury thirst, quench one's thirst, pass out semen, involuntary emission;
Polygonum multiflower knotweed, nature and flavor:Sweet slight bitter, put down, have nourishing heart, calm the nerves, dredging collateral, wind-dispelling the effect of, for treating insomnia, internal lesion caused by overexertion, more The illnesss such as sweat, deficiency of blood bodily pain, ulcer, scrofula, wind sore scabies tinea;
The coptis, nature and flavor:It is bitter, cold, there is the effect of purging intense heat, eliminating dampness, removing toxic substances, desinsection, row heat toxin, typhoid fever, excess heat during for treating Vexed, feeling of fullness vomit inverse, bacillary dysentery, heat rush down stomachache, lung knot by, tell, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, throat swell Bitterly, the burning hot wound of pinkeye, aphtha, skin sore, eczema, soup;
The tuber of dwarf lilyturf, nature and flavor:Sweet, slight bitter, it is slightly cold, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease Cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria;
Radix Angelicae Sinensis, nature and flavor:Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type stomachache, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury;
Polygala, nature and flavor:Bitter, pungent, tepor, there is the effect of tranquilize the mind and promote the intelligence, eliminating the phlegm, detumescence, for treating caused by breakdown of the normal physiological coordination between the heart and the kidney Insomnia and dreamful sleep, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, mastosis;
Radix glycyrrhizae, nature and flavor:It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning.
Medicine of the present invention is the principle based on traditional Chinese medicine in treating insomnia, is recognized from the pathomechanism according to insomnia and pharmacological action For:With regard to insomnia, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned insomnia, the medicine prepared using the formula Good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the specific of the present invention Embodiment is described in further detail:
Embodiment 1:
A kind of Chinese medicine composition for treating insomnia, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition It is as follows:
Husked sorghum 12g, Poria cocos 22g, spina date seed 20g, radix scutellariae 12g, fruit of Chinese wolfberry 20g, red sage root 12g, lily 12g, fruit of Chinese magnoliavine 12g, night Hand over rattan 20g, coptis 5g, tuber of dwarf lilyturf 20g, Radix Angelicae Sinensis 12g, polygala 10g, radix glycyrrhizae 10g.
Embodiment 2:
A kind of Chinese medicine composition for treating insomnia, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition It is as follows:
Husked sorghum 14g, Poria cocos 25g, spina date seed 23g, radix scutellariae 14g, fruit of Chinese wolfberry 23g, red sage root 14g, lily 14g, fruit of Chinese magnoliavine 14g, night Hand over rattan 23g, coptis 5.5g, tuber of dwarf lilyturf 22g, Radix Angelicae Sinensis 14g, polygala 11g, radix glycyrrhizae 11g.
Embodiment 3:
A kind of Chinese medicine composition for treating insomnia, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition It is as follows:
Husked sorghum 16g, Poria cocos 28g, spina date seed 26g, radix scutellariae 16g, fruit of Chinese wolfberry 26g, red sage root 16g, lily 16g, fruit of Chinese magnoliavine 16g, night Hand over rattan 26g, coptis 6g, tuber of dwarf lilyturf 25g, Radix Angelicae Sinensis 16g, polygala 12g, radix glycyrrhizae 12g.
Model case
Through clinical conditions insomniac totally 2320, the age is 1170 of more than 30 years old, only 1150 for 30 years old with Under.1950 to be fully recovered in 2320 patients, effective 370, total effective rate is up to 100%.

Claims (3)

1. a kind of Chinese medicine composition for treating insomnia, it is characterised in that each component and its mass parts of the Chinese medicine composition Than as follows:
9~16g of husked sorghum, 15~28g of Poria cocos, 10~26g of spina date seed, 5~16g of radix scutellariae, 10~26g of the fruit of Chinese wolfberry, 8~16g of the red sage root, 6~16g of lily, 3~16g of the fruit of Chinese magnoliavine, 10~26g of Polygonum multiflower knotweed, 3~6g of the coptis, 10~25g of the tuber of dwarf lilyturf, 8~16g of Radix Angelicae Sinensis, polygala 3 ~12g, 3~12g of radix glycyrrhizae.
2. it is according to claim 1 treatment insomnia Chinese medicine composition, it is characterised in that the Chinese medicine composition it is each Component and its mass parts are than as follows:
10~14g of husked sorghum, 17~25g of Poria cocos, 11~23g of spina date seed, 6~14g of radix scutellariae, 11~23g of the fruit of Chinese wolfberry, the red sage root 9~ 14g, 7~14g of lily, 6~14g of the fruit of Chinese magnoliavine, 11~23g of Polygonum multiflower knotweed, 4~5.5g of the coptis, 12~22g of the tuber of dwarf lilyturf, Radix Angelicae Sinensis 10~ 14g, 6~11g of polygala, 5~11g of radix glycyrrhizae.
3. the Chinese medicine composition of the treatment insomnia according to claim 1 to 2, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows:
Husked sorghum 12g, Poria cocos 22g, spina date seed 20g, radix scutellariae 12g, fruit of Chinese wolfberry 20g, red sage root 12g, lily 12g, fruit of Chinese magnoliavine 12g, night Hand over rattan 20g, coptis 5g, tuber of dwarf lilyturf 20g, Radix Angelicae Sinensis 12g, polygala 10g, radix glycyrrhizae 10g.
CN201710630017.9A 2017-07-28 2017-07-28 A kind of Chinese medicine composition for treating insomnia and preparation method thereof Withdrawn CN107397901A (en)

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