CN1073868A - The preparation method of lower abdome stagnation clearing pills - Google Patents
The preparation method of lower abdome stagnation clearing pills Download PDFInfo
- Publication number
- CN1073868A CN1073868A CN 92109997 CN92109997A CN1073868A CN 1073868 A CN1073868 A CN 1073868A CN 92109997 CN92109997 CN 92109997 CN 92109997 A CN92109997 A CN 92109997A CN 1073868 A CN1073868 A CN 1073868A
- Authority
- CN
- China
- Prior art keywords
- prescription
- rhizoma
- fry
- preparation
- stir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The preparation method of a kind of Chinese medicine---lower abdome stagnation clearing pills, comprise with water and make solvent, boil effective ingredient in the abundant extraction medicine by decocting, and before decocting boils, the medical material that contains volatile oil is carried out distillating extracting oil, with steps such as mixings in the calcium carbonate absorption back adding medicated powder.Every heavy 0.32g, contain crude drug 0.89g, the content of every Radix Paeoniae Rubra glucoside is not less than 0.6mg.
Description
The invention provides a kind of preparation method of Chinese medicine-lower abdome stagnation clearing pills, belong to the technology of preparing of the medical drugs in the medical science.
One one the 397th page of in 1990 version of Chinese Pharmacopoeia carry the prescription of record Shao Fu Zu Yu Wan, and " above ten flavors is ground into fine powder, sieve mixing.Every 100g powder adds the close 100-110g of refining and makes big close ball, method for making promptly ".This pill blood circulation and removing stasis, cold relieving pain relieving.Be used for blood stasis cold menoxenia, lower abdominal distention pain, the lumbago that causes, leucorrhea are arranged.Because of close ball system by former powder of Chinese medicine and close the mixing of refining, taking the back pill has individual dispersive process in gastrointestinal tract, especially effective ingredient discharges from the crude drug powder and by intestinal absorption, it is longer relatively to take time, and therefore, pill exists onset slow, the effective ingredient performance is abundant inadequately, the deficiency that dosage is bigger than normal.
The purpose of this invention is to provide a kind of effective ingredient that makes and give full play to its therapeutical effect, rapid-action, the preparation method of the lower abdome stagnation clearing pills of being convenient to store.
Lower abdome stagnation clearing pills provided by the present invention, its prescription is:
Radix Angelicae Sinensis 178g Pollen Typhae 178g Oletum Trogopterori (vinegar stir-fry) 118g
Radix Paeoniae Rubra 118g Fructus Foeniculi (salt stir-fry) 59g Rhizoma Corydalis (vinegar system) 59g
Myrrha (stir-fry) 59g Rhizoma Chuanxiong 59g Cortex Cinnamomi 59g
Rhizoma Zingiberis Preparatum 12g
Adjuvant:
Calcium carbonate 5-7g starch (medicinal) 30-40g
Pulvis Talci (medicinal) 10-14g.
Preparation method:
1, measures Rhizoma Corydalis by prescription and wear into fine powder;
2, measure Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Foeniculi, Cortex Cinnamomi, Rhizoma Zingiberis Preparatum by prescription and add thermal distillation 3-5 hour, extract volatile oil;
3, medicinal residues and prescription amount Pollen Typhae (decocting a drug wrapped), Oletum Trogopterori (decocting a drug wrapped), Radix Paeoniae Rubra, Myrrha decoct with water three times behind the extraction volatile oil, merge decoction liquor, filter, and concentrated filtrate becomes thick paste;
4, the filtrate thick paste adds the Rhizoma Corydalis fine powder and mixes thoroughly, and crushed after being dried is crossed 100 mesh sieves;
5, with adding 100 mesh sieve gained medicated powder with the equivalent dilution method behind the calcium carbonate absorption volatile oil;
6, upwards a gained medicated powder adds starch, uses 90-95% ethanol, granulates drying with 14 order nylon wires;
7, add Pulvis Talci to dry product and make lubricant,, charge and attack and make 1000, sugar coating with 12 order nylon wire granulate.Every contains crude drug 0.89 gram.
The preparation method of lower abdome stagnation clearing pills provided by the present invention, profit uses water as solvent, boil effective ingredient in the abundant extraction medicine by decocting, and before decocting boils, the medical material that contains volatile oil is carried out distillating extracting oil, absorb the back with calcium carbonate and add mixing in the medicated powder, the effective ingredient effect of prescription Chinese medicine is obviously increased.By in the prescription as the assay of the monarch drug Radix Paeoniae Rubra of lower abdome stagnation clearing pills major quality controlling index, adopt high performance liquid chromatogram to algorithm, find to utilize the prepared lower abdome stagnation clearing pills of the inventive method, the content of every Radix Paeoniae Rubra glucoside is not less than 0.60mg.And the response rate meansigma methods of Radix Paeoniae Rubra glucoside is 93.8%, and CV is 3.35%.
Carry out clinical with effect amount lower abdome stagnation clearing pills and Shao Fu Zu Yu Wan control experiment, its result shows: to the influence of body blood reducing stasis model rat suppository formation, Shaofu Zhuyu tablet and pill all have thrombosis effect under the remarkable inhibition cold blood stasis state, and the tablet effect is better than pill; To the influence of rabbit lower limb vascular resistance, lower abdome stagnation clearing pills and pill all have remarkable reduction rabbit lower limb vascular resistance, improve the blood circulation effect, and the tablet effect significantly is better than pill; To the influence of bacteriotoxin induced mice microcirculation disturbance, lower abdome stagnation clearing pills and pill all can significantly improve the microcirculation disturbance due to the bacteriotoxin, and wherein the tablet effect slightly is better than pill; To the spasmolysis in isolated rat uterus, experiment shows that the spasmolysis of tablet is better than pill; To the analgesic activity of oxytocin induced mice pain, lower abdome stagnation clearing pills and pill all have remarkable analgesic activity, and the tablet effect is better than pill.Find out that from the experiment of five aspects of being carried out clinical Shaofu Zhuyu tablet with the effect amount is all strong than pill effect, and present with tablet dose and increase, act on enhanced dose-effect relationship.
Because it is lower abdome stagnation clearing pills is the tablet that makes after the Chinese medicine extracts active ingredients, all good on the rate of release of effective ingredient and infiltration rate than pill.Therefore, have rapid-action, effective ingredient performance fully, good effect is convenient to store, the advantage of taking convenience.
Clinical practice shows that lower abdome stagnation clearing pills compares with Shao Fu Zu Yu Wan, and its function has increased diseases such as can be used for treating dysmenorrhea, chronic pelvic inflammatory disease, adnexitis, habitual abortion with curing mainly.
Below by better embodiment, further narrate the technical characterictic of Shaofu Zhuyu piece preparation method of the present invention.
Prescription:
Radix Angelicae Sinensis 178g Pollen Typhae 178g Oletum Trogopterori (vinegar stir-fry) 118g
Radix Paeoniae Rubra 118g Fructus Foeniculi (salt stir-fry) 59g Rhizoma Corydalis (vinegar system) 59g
Myrrha (stir-fry) 59g Rhizoma Chuanxiong 59g Cortex Cinnamomi 59g
Rhizoma Zingiberis Preparatum 12g
Adjuvant:
Calcium carbonate 6g starch (medicinal) 34.9g
Pulvis Talci (medicinal) 12.8g.
Preparation method:
1, measures Rhizoma Corydalis by prescription and wear into fine powder;
2, measure Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Foeniculi, Cortex Cinnamomi, Rhizoma Zingiberis Preparatum by prescription and added thermal distillation 4 hours, extract volatile oil;
3, medicinal residues and prescription amount Pollen Typhae (decocting a drug wrapped), Oletum Trogopterori (decocting a drug wrapped), Radix Paeoniae Rubra, Myrrha decoct with water three times behind the extraction volatile oil, first and second time adds 8 times of amounts of water, each 1.5 hours, add 6 times of amounts of water for the third time, decocted 1 hour, collecting decoction filters, concentrated filtrate becomes thick paste, the rate of extract 20-30%;
4, the filtrate thick paste adds the Rhizoma Corydalis fine powder and mixes thoroughly, and crushed after being dried is crossed 100 mesh sieves;
5, with calcium carbonate absorb wave oil after, added 100 mesh sieve gained medicated powder with the equivalent dilution method;
6, upwards a gained medicated powder adds starch, uses 95% ethanol, granulates with 14 order nylon wires, and is dry under 45 ℃ of-55 ℃ of temperature;
7, add Pulvis Talci to dry product and make lubricant,, charge and attack and make 1000, sugar coating with 12 order nylon wire granulate.
Claims (2)
1, a kind of preparation method of Chinese medicine-lower abdome stagnation clearing pills is characterized in that prescription is:
Radix Angelicae Sinensis 178g Pollen Typhae 178g Oletum Trogopterori (vinegar stir-fry) 118g
Radix Paeoniae Rubra 118g Fructus Foeniculi (salt stir-fry) 59g Rhizoma Corydalis (vinegar system) 59g
Myrrha (stir-fry) 59g Rhizoma Chuanxiong 59g Cortex Cinnamomi 59g
Rhizoma Zingiberis Preparatum 12g
Adjuvant:
Calcium carbonate 5-7g starch (medicinal) 30-40g
Pulvis Talci (medicinal) 10-14g;
Preparation method:
(1) measures Rhizoma Corydalis by prescription and wear into fine powder;
(2) measure Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Foeniculi, Cortex Cinnamomi, Rhizoma Zingiberis Preparatum by prescription and add thermal distillation 3-5 hour, extract volatile oil;
(3) medicinal residues and prescription amount Pollen Typhae (decocting a drug wrapped), Oletum Trogopterori (decocting a drug wrapped), Radix Paeoniae Rubra, Myrrha decoct with water three times behind the extraction volatile oil, merge decoction liquor, filter, and concentrated filtrate becomes thick paste;
(4) the filtrate thick paste adds the Rhizoma Corydalis fine powder and mixes thoroughly, and crushed after being dried is crossed 100 mesh sieves;
(5) with calcium carbonate absorb wave oil after, added 100 mesh sieve gained medicated powder with the equivalent dilution method;
(6) upwards a gained medicated powder adds starch, uses 90-95% ethanol, granulates drying with 14 order nylon wires;
(7) add Pulvis Talci to dry product and make lubricant,, charge and attack and make 1000, sugar coating with 12 order nylon wire granulate.
2, a kind of preparation method of Chinese medicine-lower abdome stagnation clearing pills is characterized in that prescription:
Radix Angelicae Sinensis 178g Pollen Typhae 178g Oletum Trogopterori (vinegar stir-fry) 118g
Radix Paeoniae Rubra 118g Fructus Foeniculi (salt stir-fry) 59g Rhizoma Corydalis (vinegar system) 59g
Myrrha (stir-fry) 59g Rhizoma Chuanxiong 59g Cortex Cinnamomi 59g
Rhizoma Zingiberis Preparatum 12g
Adjuvant:
Calcium carbonate 6g starch (medicinal) 34.9g
Pulvis Talci (medicinal) 12.8g;
Preparation method:
(1) measures Rhizoma Corydalis by prescription and wear into fine powder;
(2) measure Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Foeniculi, Cortex Cinnamomi, Rhizoma Zingiberis Preparatum by prescription and added thermal distillation 4 hours, extract volatile oil;
(3) medicinal residues and prescription amount Pollen Typhae (decocting a drug wrapped), Oletum Trogopterori (decocting a drug wrapped), Radix Paeoniae Rubra, Myrrha decoct with water three times behind the extraction volatile oil, first and second time adds 8 times of amounts of water, each 1.5 hours, add 6 times of amounts of water for the third time, decocted 1 hour, collecting decoction filters, concentrated filtrate becomes thick paste, the rate of extract 20-30%;
(4) the filtrate thick paste adds the Rhizoma Corydalis fine powder and mixes thoroughly, and crushed after being dried is crossed 100 mesh sieves;
(5) with calcium carbonate absorb wave oil after, added 100 mesh sieve gained medicated powder with the equivalent dilution method;
(6) upwards a gained medicated powder adds starch, uses 95% ethanol, granulates with 14 order nylon wires, and is dry under 45 ℃ of-55 ℃ of temperature;
(7) add Pulvis Talci to dry product and make lubricant,, charge and attack and make 1000, sugar coating with 12 order nylon wire granulate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92109997 CN1073868A (en) | 1992-10-27 | 1992-10-27 | The preparation method of lower abdome stagnation clearing pills |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92109997 CN1073868A (en) | 1992-10-27 | 1992-10-27 | The preparation method of lower abdome stagnation clearing pills |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1073868A true CN1073868A (en) | 1993-07-07 |
Family
ID=4944546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92109997 Pending CN1073868A (en) | 1992-10-27 | 1992-10-27 | The preparation method of lower abdome stagnation clearing pills |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1073868A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829247A (en) * | 2010-05-20 | 2010-09-15 | 南京中医药大学 | Chinese medicinal compound effective component for treating gynecological diseases and preparation method and application thereof |
| CN103784663A (en) * | 2014-01-15 | 2014-05-14 | 闫玉枝 | Traditional Chinese medicine for treating tubal obstruction |
-
1992
- 1992-10-27 CN CN 92109997 patent/CN1073868A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829247A (en) * | 2010-05-20 | 2010-09-15 | 南京中医药大学 | Chinese medicinal compound effective component for treating gynecological diseases and preparation method and application thereof |
| CN103784663A (en) * | 2014-01-15 | 2014-05-14 | 闫玉枝 | Traditional Chinese medicine for treating tubal obstruction |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101066303A (en) | Medicine for treating cerebral thrombus, cerebral angiosclerosis, apoplexy and hemiplegia and its prepn | |
| CN1073869A (en) | The preparation method of Shaofu Zhuyu electuary | |
| CN1073868A (en) | The preparation method of lower abdome stagnation clearing pills | |
| CN1219532C (en) | Chinese herbal medicine for treating gynecology disease and its preparing method | |
| CN110507708B (en) | Safflower Xiaoyao preparation for treating hyperplasia of mammary glands and preparation method and application thereof | |
| CN1712060A (en) | Preparation of Chinese medicinal mixture for treating gynecologic menstrual disease | |
| CN108514627B (en) | Traditional Chinese medicine composition for treating chronic urticaria | |
| CN101455813A (en) | Traditional Chinese medicine preparation capable of improving memory and treating amnesia and preparation method thereof | |
| CN102430073B (en) | Medicinal composition for treating peptic ulcer | |
| CN110946897A (en) | Cihang tablet and preparation method thereof | |
| CN1965918A (en) | 'Pen Yan Jing' tablet for treating gynecopathy | |
| CN1919273B (en) | Chinese medicinal composition for treating headache | |
| CN116870076B (en) | Anti-inflammatory analgesic traditional Chinese medicine composition and preparation method and application thereof | |
| CN1225269C (en) | Medicine for treating prospoalgia | |
| CN113679757B (en) | Pharmaceutical composition for improving bladder contractility and application thereof | |
| CN113101330B (en) | Menstruation regulating composition and application thereof | |
| CN110215474B (en) | Traditional Chinese medicine composition for promoting blood circulation to remove blood stasis and application thereof | |
| CN103356731A (en) | Xuesaitong tablet containing eucommia extract and panax notoginseng saponins and application thereof | |
| CN1814250A (en) | Chinese medicine composition for treating liver cirrhosis ascites and use thereof | |
| CN1238028C (en) | Method for preparing capsule of six drugs containing rehmannine | |
| CN1053381C (en) | Drug for promoting puerperal physiological recovery and curing postpartum disease | |
| CN1235605C (en) | Medicinal composition for treating gall | |
| CN101693065A (en) | Medicament for treating polymyalgia rheumatica and preparation method thereof | |
| CN1062145C (en) | Piles curing liquid | |
| CN104857213B (en) | Preparation method of traditional Chinese medicine composition for treating nephropathy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |