CN107300745B - A kind of chip clamping and flow control apparatus suitable for a variety of prisms - Google Patents

A kind of chip clamping and flow control apparatus suitable for a variety of prisms Download PDF

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Publication number
CN107300745B
CN107300745B CN201710721617.6A CN201710721617A CN107300745B CN 107300745 B CN107300745 B CN 107300745B CN 201710721617 A CN201710721617 A CN 201710721617A CN 107300745 B CN107300745 B CN 107300745B
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CN
China
Prior art keywords
prism
control apparatus
flow control
fixed
clamping device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201710721617.6A
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Chinese (zh)
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CN107300745A (en
Inventor
张蓓
荆嘉伟
刘雨
闫鹏
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Beijing University of Aeronautics and Astronautics
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Beijing University of Aeronautics and Astronautics
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Priority to CN201710721617.6A priority Critical patent/CN107300745B/en
Publication of CN107300745A publication Critical patent/CN107300745A/en
Application granted granted Critical
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Expired - Fee Related legal-status Critical Current
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/18Mountings, adjusting means, or light-tight connections, for optical elements for prisms; for mirrors
    • G02B7/1805Mountings, adjusting means, or light-tight connections, for optical elements for prisms; for mirrors for prisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention proposes a kind of chip clamping suitable for a variety of prisms and flow control apparatus, belong to nanometer detection and photoelectric sensing field.The present invention consists of three parts, and is device pedestal, prism clamping device and fluid storage device respectively.Wherein there are threaded hole and counterbore on pedestal.Whole device for fixed prism clamping device and is fixed on third-party platform by pedestal.Prism clamping device is L-type framework, its bottom through-hole is used for and pedestal is fixed, its vertical plane is used for fixed prism and fluid storage device, and equilateral prism bracket can be used on prism clamping device vertical plane and right-angle prism bracket is respectively used to fixed equilateral prism and right-angle prism.Fluid storage device is rectangular block, and there is the groove for storing liquid at the center of rectangular block one side, while liquid can pass through the threaded hole inflow and outflow groove on rectangular block.

Description

A kind of chip clamping and flow control apparatus suitable for a variety of prisms
Technical field
The present invention relates to a kind of chip clamping suitable for a variety of prisms and flow control apparatus, belong to nanometer detection and photoelectric transfer Sense field.
Background of invention
Surface plasma body resonant vibration (Surface Plasmon Resonance, SPR) sensing technology is a kind of novel light Electro-detection technology is widely used in biologic medical field.The micro- system of surface plasma of Kretchmann proposition lens type System, the system early stage proposed are widely used in the detection of solid sample, and current biological, medicine, environment, chemistry etc. for The detection demand of liquid phase sample is very big, and liquid phase sample lacks effective liquid storage and chip clamping device when detecting.
In the detection process of liquid phase sample, liquid needs are more uniform to be distributed in censorchip surface, and device needs Inflow and outflow and its flow velocity of liquid can be controlled.There is micro-fluidic function to be capable of fixing print simultaneously and flow liquid not for research and development It loses necessary.The invention proposes one kind can effectively clamp prism and chip and effectively storage liquid phase sample while not The chip clamping that can be suitably used for a variety of prisms of damage chip structure and flow control apparatus.
Summary of the invention
(1) technical problems to be solved
The demand in biology, chemistry of the detection of liquid phase sample at present is very big, and lens type system is applied to liquid phase and detects extremely Extensively, but liquid is easier to be lost in prism surface, lacks effective sensing chip clamping and fluid control device.
(2) solution
The present invention provides a kind of chip clamping suitable for a variety of prisms and flow control apparatus, energy while fixed prism It enough fixes sensing chip and liquid can be stored in chip surface and control the inflow and outflow of liquid, have in liquid detecting field Have wide application prospects.
A kind of chip clamping and flow control apparatus suitable for a variety of prisms, comprising: device pedestal, prism fixing device and stream Control device three parts.
Device pedestal is cylindrical structure, there is the counterbore of multiple threaded holes and multiple and different specifications on pedestal, and pedestal, which rises, to be turned Effect is connect, prism fixing device can be fixed in optical system, threaded hole for connecting with prism fixing device, use by counterbore In firm banking.
Prism fixing device includes L shape framework and prism fixed frame, and the bottom surface of L shape framework is used for there are four through-hole and pedestal It connects, one rectangular space of vacancy among the vertical plane of L shape framework, in the rectangular space of the embeddable vacancy of flow control apparatus.L shape structure There are four threaded holes for fixing flow control apparatus at frame vertical plane empty portions edge;Another vertical plane of L shape framework has upper and lower two Each four threaded holes are arranged, two rows of threaded holes are used for and the cooperation of prism fixed frame is with fixed prism.Prism fixed frame has right-angle prism Frame and equilateral prism frame, right-angled edge mirror holder is for fixing right-angle prism, and right-angled edge mirror holder is 90 degree of components, and member end has two A through-hole is used for the threaded hole cooperation with every row's threaded hole both ends on L shape framework vertical plane.Equilateral prism frame is equilateral for fixing Prism, equilateral prism frame are 60 degree of components, and there are two through-holes to be used for and every row's threaded hole on L shape framework vertical plane for member end Centre two threaded holes cooperation.
Flow control apparatus middle section is rectangular block, and one side of rectangular block is protruded outward close to four corners point, and four prominent There is through-hole on part out, four threaded holes on four through-holes and L shape framework vertical plane cooperate to fix flow control apparatus.Rectangle Block one side has the circular groove of indent, and the radius and sensing chip radius of circular groove are close, includes two half-thread through-holes in circular groove, partly Two sides of tapped through hole connection rectangular block are used to control the inflow and outflow of liquid.
When assembly, screw is connected by four through-holes of pedestal of the L shape framework of prism fixing device the four of pedestal In a screw hole.Prism is fixed on the vertical plane of L shape framework by two prism fixed frames, and flow control apparatus protrudes part by it Four through-holes are fixed on the vertical plane of L shape framework, and a rounded washers are placed at the indent circular groove edge of flow control apparatus, sense core Piece one side is in contact with washer, and another side is directly contacted with prism.
Detailed description of the invention
Fig. 1 is a kind of base schematic diagram suitable for the clamping of the chip of a variety of prisms and flow control apparatus;
Fig. 2 is a kind of oblique two surveys view of prism fixing device suitable for the clamping of the chip of a variety of prisms and flow control apparatus Figure;
Fig. 3 is a kind of main view of prism fixing device suitable for the clamping of the chip of a variety of prisms and flow control apparatus;
Fig. 4 is a kind of right-angle prism bracket and equilateral prism branch suitable for the clamping of the chip of a variety of prisms and flow control apparatus The structural schematic diagram of frame;
Fig. 5 is a kind of flow control apparatus schematic diagram suitable for the clamping of the chip of a variety of prisms and flow control apparatus;
Fig. 6 assembles right-angle prism and equilateral prism for a kind of chip clamping suitable for a variety of prisms and flow control apparatus respectively Overall schematic;
Wherein in Fig. 1: 101: threaded hole;102: through-hole;
In Fig. 2: 201: counterbore;202: threaded hole;203: rectangle vacancy;
In Fig. 3: 204: threaded hole;205: screw thread;
In Fig. 4: 206: right-angle prism bracket;207 equilateral prism brackets;
In Fig. 5: 301: through-hole;302: threaded hole;303 circular grooves;
In Fig. 6: 1: clamping device pedestal;2: prism fixing device;3: flow control apparatus;4: right-angle prism;5: equilateral prism.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Following instance For illustrating the present invention, but it is not intended to limit the scope of the invention.
In the description of the present invention, it should be noted that term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower", The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", "outside" is It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair Limitation of the invention.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition Concrete meaning in invention.
Specific embodiment 1:
As shown in Figs. 1-5, the present invention provides a kind of chip clamping suitable for a variety of prisms and flow control apparatus comprising Clamping device pedestal 1, prism fixing device 2 and the flow control apparatus 3 being successively cooperatively connected, the flow control apparatus 3 are solid positioned at prism Determine in device 2;
As shown in Figure 1, there are four threaded hole 101 and six through-holes 102 on pedestal, threaded hole 101 is solid for fixed prism Determine device 2, through-hole 102 can be such that through-hole is fixed on other devices;
As Figure 2-Figure 5, four through-holes 201 on 2 bottom of prism fixing device are used for and four screw threads on pedestal The cooperation of hole 101 is with the fixed device 2 of fixed prism.Rectangle vacancy 203 is for placing flow control apparatus on 2 vertical plane of prism fixing device 3, four threaded holes 202 on 2 vertical plane of prism fixing device are for fixing flow control apparatus 3.As shown in figure 3, the fixed dress of prism The another side for setting 2 vertical planes has two rows threaded hole, and every row has threaded hole four, wherein two threaded holes per exclusive side 204 for fixing right-angle prism bracket 206.
As shown in figure 5, there are four through-hole on the edge projection 301 of flow control apparatus 3, four through-holes 301 and prism are solid Determine four on device 2 threaded holes 202 to match to fix flow control apparatus, there are two threaded holes 302 on flow control apparatus one side For controlling flowing in and out for liquid, there is circular groove 303 on the another side of flow control apparatus, 303 edge of circular groove is put It sets and places sensing chip on a rounded washers and then washer.Chip-side is close to washer, when liquid flow membership is stored in flow control In the enclosure space that device cup washer and sensing chip are formed, prism is close in the other side of chip.
As shown in left side in Fig. 6, two right-angle prism brackets 206 can be used to fix right-angle prism 4.
Specific embodiment 2:
On the basis of specific embodiment one, when assembling equilateral prism 5, equilateral prism 5 is placed on prism and is consolidated Determine on device vertical plane, reuses equilateral prism bracket 207 to fix equilateral prism 5, equilateral prism bracket 207 is fixed on screw thread On hole 205, assembly result is as shown in right side in Fig. 6.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (4)

1. a kind of chip clamping and flow control apparatus suitable for a variety of prisms, it is characterised in that: including clamping device pedestal, prism Clamping device and flow control apparatus, wherein there is threaded hole and counterbore on pedestal, pedestal is used for fixed prism clamping device and will be entire Device is fixed on third-party platform;Prism clamping device is L-type framework, and bottom through-hole is used for and pedestal is fixed, vertical Face is used for fixed prism and flow control apparatus, and equilateral prism bracket and right-angle prism branch can be used on prism clamping device vertical plane Frame is respectively used to fixed equilateral prism and right-angle prism;Flow control apparatus is rectangular block, and there is circular groove at the center of rectangular block one side, There are two half-thread through-hole among circular groove, circular groove is flowed into for storing liquid, liquid by two half-thread through-holes Rounded washers are placed at circular groove, circular groove edge, and sensing chip is then placed in rounded washers, and sensing chip side is close to Washer, in the enclosure space that liquid flow membership is stored in flow control apparatus circular groove, rounded washers and sensing chip formation, It is close to prism in the other side of sensing chip.
2. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that: institute The threaded hole for having fixed equilateral prism and right-angle prism bracket on prism clamping device vertical plane is stated, the distribution of threaded hole is about this The vertical bisector of vertical plane is symmetrical.
3. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that: institute State embeddable flow control apparatus on the vertical plane of L shape prism clamping device.
4. a kind of chip clamping and flow control apparatus suitable for a variety of prisms according to claim 1, it is characterised in that: institute The prism clamping device stated can fix two kinds of prisms of equilateral prism and right-angle prism.
CN201710721617.6A 2017-08-22 2017-08-22 A kind of chip clamping and flow control apparatus suitable for a variety of prisms Expired - Fee Related CN107300745B (en)

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CN201710721617.6A CN107300745B (en) 2017-08-22 2017-08-22 A kind of chip clamping and flow control apparatus suitable for a variety of prisms

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112904650A (en) 2019-11-19 2021-06-04 青岛海信激光显示股份有限公司 Laser projection device
CN112824967B (en) * 2019-11-19 2022-04-26 青岛海信激光显示股份有限公司 Laser projection device
CN111103671B (en) * 2020-01-13 2022-06-07 吉林工程技术师范学院 Beam splitting prism assembly for off-axis three-mirror optical system and operation method thereof
CN113534400B (en) * 2021-06-29 2023-03-14 西安航天精密机电研究所 Prism assembly and assembling method thereof

Citations (5)

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Publication number Priority date Publication date Assignee Title
EP1684063A1 (en) * 2005-01-19 2006-07-26 Samsung Electronics Co.,Ltd. Portable biochip scanner using surface plasmon resonance
CN1811582A (en) * 2005-01-28 2006-08-02 台达电子工业股份有限公司 Optical assembly device and assembling method
CN101251483A (en) * 2008-01-11 2008-08-27 北京赛德创生物技术有限公司 Test analytical instrument using surface plasma resonance oscillation detection technique
CN103675053A (en) * 2013-09-27 2014-03-26 中国科学院电子学研究所 Local electrochemical imaging test system based on surface plasma resonance
CN106501219A (en) * 2016-10-19 2017-03-15 中国科学院电子学研究所 A kind of Portable, multiple parameter surface plasma resonance biochemical analyzer

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JP6477488B2 (en) * 2013-10-31 2019-03-06 コニカミノルタ株式会社 Detection device and detection method using the detection device

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
EP1684063A1 (en) * 2005-01-19 2006-07-26 Samsung Electronics Co.,Ltd. Portable biochip scanner using surface plasmon resonance
CN1811582A (en) * 2005-01-28 2006-08-02 台达电子工业股份有限公司 Optical assembly device and assembling method
CN101251483A (en) * 2008-01-11 2008-08-27 北京赛德创生物技术有限公司 Test analytical instrument using surface plasma resonance oscillation detection technique
CN103675053A (en) * 2013-09-27 2014-03-26 中国科学院电子学研究所 Local electrochemical imaging test system based on surface plasma resonance
CN106501219A (en) * 2016-10-19 2017-03-15 中国科学院电子学研究所 A kind of Portable, multiple parameter surface plasma resonance biochemical analyzer

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Granted publication date: 20191112

Termination date: 20200822