CN107253795A - Prepare device of sterilized water for injection and preparation method thereof - Google Patents
Prepare device of sterilized water for injection and preparation method thereof Download PDFInfo
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- CN107253795A CN107253795A CN201710676347.1A CN201710676347A CN107253795A CN 107253795 A CN107253795 A CN 107253795A CN 201710676347 A CN201710676347 A CN 201710676347A CN 107253795 A CN107253795 A CN 107253795A
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F9/00—Multistage treatment of water, waste water or sewage
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/001—Processes for the treatment of water whereby the filtration technique is of importance
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/02—Treatment of water, waste water, or sewage by heating
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/02—Treatment of water, waste water, or sewage by heating
- C02F1/04—Treatment of water, waste water, or sewage by heating by distillation or evaporation
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/44—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
- C02F1/441—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis by reverse osmosis
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2301/00—General aspects of water treatment
- C02F2301/08—Multistage treatments, e.g. repetition of the same process step under different conditions
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2303/00—Specific treatment goals
- C02F2303/04—Disinfection
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- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Engineering & Computer Science (AREA)
- Environmental & Geological Engineering (AREA)
- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention discloses a kind of device for preparing sterilized water for injection and preparation method thereof, including upper tank body, first filter, lower tank, indirect steam tank, second filter and finished product collection device, raw water filters out partial impurities after entering upper tank body through the first filter, steam is formed in lower tank, pass through the double evaporation-cooling of double evaporation-cooling tank after condensation again, through refined filtration twice after condensing again, finally water quality is detected in finished product collection device, after water quality meets indices, detection tank is connected with finished pot, water is put into finished pot, water in the finished pot sterilization treatment after embedding produces sterilized water for injection, and water quality it is unqualified when, then make water back flow back into upper tank body to process again until water quality is qualified.It is low to water quality requirement, and apparatus structure is simply easy to safeguard, while to the real-time detection of water quality, improving the quality and safety in utilization of sterilized water for injection.Preparation process is simply easy to grasp simultaneously, effectively reduces preparation cost.
Description
Technical field
The present invention relates to medical processing technique field, more particularly to a kind of device for preparing sterilizing direct projection water and its preparation
Method.
Background technology
With the development of modern science and technology, pharmaceutical factory, hospital and R＆D institution etc. will to the production of used water for injection
Continuous improvement is asked, this requires production equipment enterprise to provide efficient, high-quality equipment, so as to ensure the matter of water for injection
Amount, while the equipment produced can reach the targets such as energy-conservation, service life length.But in the market using it is most be multiple-effect
Distillation machine, such a equipment using process aquifer yield is small, high energy consumption, service life of equipment is short, floor space is big, water quality is unstable
It is fixed, high is required to raw water quality, production efficiency is have impact on, and device structure is complicated, maintenance maintenance cost is too high, so at this stage
How more efficiently high-quality production sterilized water for injection is particularly important.
The content of the invention
It is an object of the invention to solve at least the above, and provide the advantage that at least will be described later.
It is low to water quality requirement it is a still further object of the present invention to provide a kind of device for preparing sterilized water for injection, and dress
Put it is simple in construction be easy to safeguard, while to the real-time detection of water quality, improving the quality and safety in utilization of sterilized water for injection.
It is a still further object of the present invention to provide a kind of preparation method of sterilized water for injection, preparation process is simply easy to the palm
Hold, effectively reduce preparation cost.
In order to realize that there is provided a kind of dress for preparing sterilized water for injection according to object of the present invention and further advantage
Put, including：
Upper tank body, its top center is provided with the pipeline for protruding from the upper tank body upper surface, and the pipeline is in protrusion institute
The one end for stating upper tank body surface is connected with Y tube, and the long end interface of the Y tube is connected with the pipeline, the Y tube
Another two ends are respectively to be used for the raw water input port of raw water input and the annex solution input port for adding annex solution；The upper tank body
Agitating device is inside provided with, the agitating device includes rotary shaft and stirring vane, and the rotary shaft is vertically installed on described
Tank interior, and the two ends of the upper tank body are fixed on, the rotary shaft is set to be hollow, and is communicated with the pipeline, described
Stirring vane is the hollow setting that another end opening is closed in one end, and the openend of the stirring vane is connected with rotary shaft, and with
Perforate is provided with the inside connection of the rotary shaft, the side of the stirring vane and top surface；
First filter, it includes the first filter cartridge and the first filter membrane, the top of first filter cartridge with it is described on
The lower removable connection of tank body, and with the upper tank body fluid communication, first filter membrane is arranged at first filter cartridge
Inside, and the inwall at the edge of first filter membrane and first filter cartridge fits；
Lower tank, its top is provided with the first liquid storage box, the side wall of first liquid storage box and bottom surface and is provided with first
Heating plate, first liquid storage box is internally provided with the first temperature sensor being connected with first heating plate；Described
The upper end of one liquid storage box is connected with the lower removable of first filter cartridge, and the lower end connection first of first liquid storage box is atomized
Pipeline, the first atomization pipeline is set for waveform, and the first atomization pipeline is in the side towards the lower tank bottom surface
The first atomization mouthful is set up；It is provided with the bottom surface of the lower tank centered on the first quartz plate, first quartz plate
Downwardly projecting concave structure, the bottom of first quartz plate is provided with primary heater；Above the side wall of the lower tank
It is provided with the first steam (vapor) outlet；
Indirect steam tank, its side wall is provided with steam inlet, and first steam (vapor) outlet passes through the first spiral cold-finger and institute
State steam inlet to be connected, the second liquid storage box, second storage are connected with the steam inlet in the indirect steam tank
It is provided with the second heating plate on the side wall of liquid box and bottom surface, second liquid storage box is internally provided with and second heating plate
Connected second temperature sensor；The lower end connection second of second liquid storage box is atomized pipeline, and the second atomization pipeline is
Waveform is set, and the second atomization pipeline is provided with the second atomization on the direction towards the indirect steam tank bottom face
Mouthful；Downwardly projecting concave structure centered on the second quartz plate, second quartz plate is provided with the bottom surface of the lower tank,
The bottom of second quartz plate is provided with secondary heater；The second steam (vapor) outlet is provided with above the side wall of the lower tank；
Second filter, it includes the second filter cartridge, the second filter membrane and the 3rd filter membrane, the inwall of second filter cartridge
On be arranged with 2 road necks in parallel, second filter membrane and the 3rd filter membrane are respectively engaged with described in 2 roads in neck, second mistake
Filter device is arranged at the bottom of the indirect steam tank, and is connected by the second spiral cold-finger with second steam (vapor) outlet
Connect；
Finished product collection device, it includes being provided with water quality detection in detection tank, finished pot and three-way valve, the detection tank
Device, the Water quality detector is connected with the three-way valve, with according to water quality detection output control three-way valve it is each
The opening and closing of individual liquid outlet, and it is described detection tank be connected with the liquid outlet of second filter, the two of the three-way valve
Individual liquid outlet connects finished pot and detection tank respectively, and another liquid outlet of the three-way valve is connected to described by catheter
Pipeline.
Preferably, in the described device for preparing sterilized water for injection, in addition to：
Drive control mechanism, itself and the rotary shaft, the first temperature sensor, second temperature sensor, primary heater
Connected respectively with secondary heater.
Preferably, in the described device for preparing sterilized water for injection, air inlet is offered on the side wall of the upper tank body
Valve.
Preferably, in the described device for preparing sterilized water for injection, set in the lower tank and indirect steam tank
Have and urgent air bleeding valve, and the urgent air bleeding valve are provided with pressure sensor, the side wall of lower tank and the indirect steam tank
It is controlled by the pressure sensor.
Preferably, in the described device for preparing sterilized water for injection, check valve is provided with the pipeline.
Preferably, in the described device for preparing sterilized water for injection, first filter membrane, the second filter membrane and the 3rd filter
Film is reverse osmosis filter membrane, and the aperture of first filter membrane is 0.4-0.5 μm, the aperture of second filter membrane and the 3rd filter membrane
For 0.2-0.25 μm.
Preferably, in the described device for preparing sterilized water for injection, the top of first filter is respectively provided with
There is baffle plate, the baffle plate is embedded in the groove of the upper tank body bottom, so as to the baffle plate is pulled, the upper tank body and the first mistake
Filter device fluid communication.
Preferably, in the described device for preparing sterilized water for injection, first spiral cold-finger and the second spiral
Condenser pipe is integrally that inclined S-shaped is set, and one end of first helix tube and the second helix tube connection steam (vapor) outlet is high
In the other end, meanwhile, the radian of the S-shaped of one end of the first helix tube and the second helix tube the connection steam (vapor) outlet is less than described
The radian of the other end of first helix tube and the second helix tube；In addition, first spiral cold-finger and the second spiral cold-finger
It is tool double-decker with dissection, and first spiral cold-finger and the second spiral cold-finger connect one end of steam (vapor) outlet
Cooling water intake is respectively arranged with, the other end of first spiral cold-finger and the second spiral cold-finger is provided with cooling water
Delivery port, and the cooling water intake and cooling water outlet are connected to raw water input, so as to be formed in the interlayer
Cooling water circulation.
Preferably, in the described device for preparing sterilized water for injection, raw water by the raw water input port before being entered
Also need by quartz sand and activated carbon filtering.
A kind of method for preparing sterilized water for injection with the described device for preparing sterilized water for injection, including following step
Suddenly：
Step 1, at the two ends of the Y tube by the weight ratio of raw water and annex solution it is 1:0.003-0.005 is each led into
Raw water and annex solution, mixing obtain the first mixed liquor；
Wherein, the annex solution is the mixed liquor of alkalinity potassium permanganate and phosphoric acid；
Step 2, the first mixed liquor through first membrane filtration removed into sediment, and to the first liquid storage box of lower tank
In be heated to 80 DEG C, and through the first atomization pipeline atomization；
The atomized liquid that step 3, step 2 are generated obtains just steaming vapor after heating through quartz plate；
Step 4, just steaming vapor enter indirect steam tank after the first spiral cold-finger, and by two in indirect steam tank
Secondary heating obtains the second vapor；
Obtain primary injection water after step 5, the second vapor are condensed, and it is dual through the second filter membrane and the 3rd filter membrane
Filtering, obtains secondary injection water；
Step 6, secondary injection water through Water quality detector detection it is qualified after, through 100 DEG C of flowing steam sterilization 25-
After 40min, the sterilized water for injection is produced.
The present invention at least includes following beneficial effect：
The present invention is by setting upper tank body, lower tank, indirect steam tank and filter at different levels so that raw water is in addition
Wherein each kind of micro substance is eliminated under the processing of liquid, and then is tentatively filtrated to get more pure water, then by lower tank
The purified water for being thermally formed vapor, obtaining after one-level distillation of body, then passes through the second distillation of indirect steam tank again so that
Water quality is further purified, and eventually passes double-filtration, obtains pure water for injection, and apparatus structure is simple and automaticity
Height, effectively reduces maintenance and the maintenance cost of device, and then reduces the production cost of sterile water for injection, is easy to extensive
Promote the use of.
By being set in upper tank body, the stirring vane of hollow rotary shaft and special construction, enables to raw water through pipe
When road enters upper tank body, passed through by rotary shaft and stirring vane, and through hole be provided with the side of stirring vane and top surface so that
When raw water is flowed out by through hole, the motive force of stirring vane forward is given, and then cause rotary shaft to drive stirring vane rotation more to save
Power, saves the energy, and the through hole of top surface make it that raw water is flowed upwards out, and promotes the rolling of raw water in upper tank body, and then to add
Liquid feeding and raw water mixing are more complete, are easy to annex solution to remove the various materials in raw water.
By setting heating plate and temperature sensor respectively in the first and second liquid storage boxes, the heating to water can be easy to
With the control of water temperature so that moisture is more easy to be formed by evaporation to vapor.And the quartz plate of spill is wherein used, enable to
Moisture is largely gathered in the center of quartz plate, without being spread to surrounding, is easy to the aggregation and evaporation of moisture, and quartz plate matter
Ground is more pure, can further reduce the generation of impurities in water.In addition, being atomized by the waveform for being provided with atomizer
Pipeline, enables to water before the evaporation to fall in the form of atomization on quartz plate, and then causes vapor is produced more quick, enters
And the efficiency of device is improved, while corrugated atomization pipeline can store substantial amounts of water, and the aqueous vapor of atomization can be made in tank
Internal distribution is more uniform.
Fitted by the side wall for limiting filter membrane and filter cartridge so that liquid passes fully through membrane filtration, that is, ensure that into
The quality of product.
Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this
The research and practice of invention and be understood by the person skilled in the art.
Brief description of the drawings
Fig. 1 is the structural representation of the device of the present invention for preparing sterilized water for injection；
Fig. 2 is the upward view of the of the present invention first atomization pipeline and the second atomization pipeline.
Embodiment
The present invention is described in further detail below in conjunction with the accompanying drawings, to make those skilled in the art with reference to specification text
Word can be implemented according to this.
It should be appreciated that such as " having ", "comprising" and " comprising " term used herein do not allot one or many
The presence or addition of individual other elements or its combination.
As shown in figure 1, the present invention provides a kind of device for preparing sterilized water for injection, including：In upper tank body 1, its top
The heart is provided with the pipeline 2 for protruding from the upper surface of upper tank body 1, and the pipeline 2 connects in the one end for protruding the surface of upper tank body 1
Y tube 3 is connected to, the long end interface of the Y tube 3 is connected with the pipeline 2, and the another two ends of the Y tube 3 are respectively to be used for
The raw water input port of raw water input and the annex solution input port for adding annex solution；Stirring dress is provided with the upper tank body 1
Put, the agitating device includes rotary shaft 4 and stirring vane 5, the rotary shaft 4 is vertically installed in inside the upper tank body 1, and
The two ends of the upper tank body 1 are fixed on, the rotary shaft 4 is set to be hollow, and is communicated with the pipeline 2, the stirring vane 5
The hollow setting of another end opening is closed for one end, the openend of the stirring vane 5 is connected with rotary shaft 4, and with the rotation
Perforate 6 is provided with the inside connection of rotating shaft 4, the side of the stirring vane 5 and top surface.
First filter, it includes the first filter cartridge 7 and the first filter membrane, the top of first filter cartridge 7 with it is described
Upper tank body 1 lower removable connection, and with the fluid communication of upper tank body 1, first filter membrane be arranged at it is described first filtering
The inside of box 7, and the inwall at the edge of first filter membrane and first filter cartridge 7 fits.
Lower tank 8, its top, which is provided with the first liquid storage box 9, the side wall of first liquid storage box 9 and bottom surface, is provided with
One heating plate, first liquid storage box 9 is internally provided with the first temperature sensor being connected with first heating plate；It is described
The upper end of first liquid storage box 9 is connected with the lower removable of first filter cartridge 7, the lower end of first liquid storage box 9 connection the
One atomization pipeline 10, the first atomization pipeline 10 is that waveform is set, and described first is atomized pipeline 10 towards under described
The first atomization mouthful 11 is provided with the direction of the bottom surface of tank body 8；The first quartz plate 12, institute are provided with the bottom surface of the lower tank 8
Downwardly projecting concave structure centered on the first quartz plate 12 is stated, the bottom of first quartz plate 12 is provided with the first heating
Device；The first steam (vapor) outlet 13 is provided with above the side wall of the lower tank 8.
Indirect steam tank 14, its side wall is provided with steam inlet 15, and first steam (vapor) outlet 13 is condensed by the first spiral
Pipe 16 is connected with the steam inlet 15, and the second liquid storage is connected with the steam inlet 15 in the indirect steam tank 14
The second heating plate is provided with box 17, the side wall of second liquid storage box 17 and bottom surface, the inside of second liquid storage box 17 is set
It is equipped with the second temperature sensor being connected with second heating plate；The lower end of second liquid storage box 17 connects the second mist pipe
Road 19, the second atomization pipeline 19 is that waveform is set, and described second is atomized pipeline 19 towards the indirect steam tank
The second atomization mouthful 20 is provided with the direction of 14 bottom surfaces；The second quartz plate 21, described are provided with the bottom surface of the lower tank 8
Downwardly projecting concave structure centered on two quartz plates 21, the bottom of second quartz plate 21 is provided with secondary heater；Institute
State and be provided with the second steam (vapor) outlet 22 above the side wall of lower tank 8.
Second filter, it includes the second filter cartridge 23, the second filter membrane 24 and the 3rd filter membrane 25, second filter cartridge
It is arranged with 2 road necks on 23 inwall in parallel, the filter membrane 25 of the second filter membrane 24 and the 3rd is respectively engaged with neck described in 2 roads
Interior, second filter is arranged at the bottom of the indirect steam tank 14, and by the second spiral cold-finger 26 with it is described
Second steam (vapor) outlet 22 is connected.
Finished product collection device, it includes being provided with detection tank 27, finished pot 28 and three-way valve 29, the detection tank 27
Water quality detector 30, the Water quality detector 30 is connected with the three-way valve 29, with according to water quality detection output control institute
The opening and closing of each liquid outlet of three-way valve 29 is stated, and the detection tank 27 is connected with the liquid outlet of second filter
Connect, two liquid outlets of the three-way valve 29 connect finished pot 28 and detection tank 27 respectively, the three-way valve 29 it is another
Individual liquid outlet is connected to the pipeline 2 by catheter 18.
In such scheme, raw water, which enters to react with annex solution after upper tank body, gets rid of the impurity such as chlorine therein and ammonia, so
Impurity is filtered out by the first filter afterwards, steam is formed in lower tank, and the is obtained through the condensation of the first spiral cold-finger
Purified water after flush distillation, then passes through the double evaporation-cooling of double evaporation-cooling tank, further removes impurities in water, purified again
Water, purified water is passed through the filtering twice of the second filter so that the more pure free from admixture of purified water, is finally collected in finished product
In device, because being mounted with Water quality detector, water quality detection can be carried out to the water for injection that production is obtained, pH is met in water quality
After the items water for injection index such as value, electrical conductivity, Water quality detector control three-way valve and the tank connected liquid outlet of the finished product,
Finished product water for injection is put into finished pot, the sterilization treatment after embedding of the water for injection in finished pot, that is, has obtained sterilizing note
Penetrate and use water, and when Water quality detector detection finished product water for injection is unqualified, then control going out for three-way valve and catheter UNICOM
Liquid mouthful is opened so that finished product water for injection back flows back into upper tank body, is processed again, until water quality is qualified.By second
Two layers of filter membrane is set in filter, secondary fine filtering can be carried out to water for injection, to cause water quality more pure, it is ensured that medicine
Product use safety.Detected by the way that finished product water for injection is first passed through into detection tank, drug quality is further ensured, while energy
Enough monitoring water for injection quality in real time, it is to avoid underproof water for injection is mixed into qualified water, while water can be looped back again
Secondary processing, has saved water resource, has reduced production cost.Wherein, the setting of the first spiral cold-finger and the second spiral cold-finger,
So that circulation distance of the vapor in pipe rises appreciably, and then causes vapor to have time enough to be condensed into aqueous water, just
In follow-up processing and collection.
In one preferred scheme, in addition to：Drive control mechanism, itself and the rotary shaft 4, the first temperature sensor,
Two temperature sensors, primary heater and secondary heater are connected respectively.
In such scheme, although through hole on stirring vane when being passed through raw water can to stirring vane pushing away necessarily
Power, but because motive force is limited, and flow rate of water flow is unstable so that the rotation of agitating shaft is not necessarily smooth, thus by setting
Drive control mechanism, can drive rotary shaft to be rotated, and under the auxiliary of stirring vane, can save substantial amounts of energy
Source, reduces preparation cost, while by setting the temperature sensor of drive control mechanism controls first and second temperature sensor,
And then to monitor and set at any time temperature in drive control mechanism, and then ensure that vapor is smoothly produced.
In one preferred scheme, intake valve 30 is offered on the side wall of the upper tank body 1.
, can be in raw water and the mixed liquor of annex solution by opening up intake valve on the side wall of upper tank body in such scheme
During filtering, nitrogen is passed through by intake valve so that the pressure of gas can accelerated filtration, improve the operating efficiency of device, and nitrogen
Gas is practically insoluble in water, and also water quality will not be impacted.
In one preferred scheme, pressure sensor, the lower tank are provided with the lower tank 8 and indirect steam tank 14
8 and indirect steam tank 14 side wall on be provided with urgent air bleeding valve 31, and the urgent air bleeding valve 31 is controlled by the pressure and passed
Sensor.
In such scheme, by setting pressure sensor on lower tank and indirect steam tank and being controlled by the pressure
The urgent air bleeding valve of sensor, can be when pressure be excessive in tank body, outside vent water vapor, and then improves described device and make
Security.
In one preferred scheme, check valve is provided with the pipeline 2.
In such scheme, by setting check valve in pipeline so that pipeline can only convey liquid into tank body, without
Can be to outward leakage, and then being smoothed out for preparation process is ensure that, the health of tank vivo environment is also ensure that, improves and is prepared into
Water for injection quality.
In one preferred scheme, first filter membrane, the second filter membrane and the 3rd filter membrane are reverse osmosis filter membrane, and described
The aperture of one filter membrane is 0.4-0.5 μm, the aperture of second filter membrane and the 3rd filter membrane is 0.2-0.25 μm.
In such scheme, by set the first to the 3rd filter membrane be reverse osmosis membrane so that water will not counter-infiltration, and then
The security of the water quality of filtering is ensure that, meanwhile, found by substantial amounts of repetitious experiment, limit the aperture of each filter membrane to be upper
When stating numerical value, the sterile water for injection of preparation is best in quality, wherein, and using the aperture of the first filter membrane as 0.45 μm, the second filter membrane
When aperture with the 3rd filter membrane is 0.22 μm, the efficiency highest of sterile water for injection is prepared, it is best in quality.
In one preferred scheme, the top of first filter is provided with baffle plate 32, and the baffle plate 32 is embedded in institute
In the groove for stating the bottom of upper tank body 1, so as to the baffle plate 32 is pulled, the filter fluid communication of upper tank body 1 and first.
In such scheme, by setting baffle plate between filter and tank body so that mixed liquor ability when needing filtering
Baffle plate is opened, filtering can be realized, so as to avoid mixed liquor is unmixed from uniformly flowing into subsequent processing by filter.
In one preferred scheme, overall 16 and second spiral cold-finger of the first spiral cold-finger 26 is inclined S
Shape is set, and one end of the helix tube 26 of first helix tube 16 and second connection steam (vapor) outlet is higher than the other end, meanwhile, it is described
The radian of the S-shaped of one end of the first helix tube 16 and the second helix tube 26 connection steam (vapor) outlet is less than the He of the first helix tube 16
The radian of the other end of second helix tube 26；In addition, the spiral cold-finger 26 of the first spiral cold-finger 16 and second is tool
Double-decker with dissection, and one end point of the spiral cold-finger 26 of first spiral cold-finger 16 and second connection steam (vapor) outlet
Cooling water intake is not provided with, and the other end of the spiral cold-finger 26 of the first spiral cold-finger 16 and second is provided with cooling
Water delivery port, and the cooling water intake and cooling water outlet are connected to raw water input, so that shape in the interlayer
Into cooling water circulation.
In such scheme, by setting condenser pipe to be set for S-shaped so that the vapor come out by steam (vapor) outlet is passing through
There is a small amount of stop during first radian, be easy to the condensation of vapor, but integral inclined set causes condensed water not accumulate in
It is excessive at camber, and second radian is larger so that condensed water can quickly flow into subsequent processing so that the system of whole device
Standby efficiency is significantly improved.It is used as cooling water to vapor progress by setting spiral cold-finger to be double-decker, and by raw water
Condensation so that preparing cost further reduces.
In one preferred scheme, raw water is also needed by quartz sand and activated carbon mistake before being entered by the raw water input port
Filter.
In such scheme, by limiting, raw water first passes through quartz sand and activated carbon is filtered, can be first by raw water
Large granular impurity is removed, and then the preparation process of follow-up sterile direct projection water is more succinctly facilitated, and improves filter membrane
Service life.
A kind of method for preparing sterilized water for injection with the described device for preparing sterilized water for injection, including following step
Suddenly：
Step 1, at the two ends of the Y tube by the weight ratio of raw water and annex solution it is 1:0.003-0.005 is each led into
Raw water and annex solution, mixing obtain the first mixed liquor；
Wherein, the annex solution is the mixed liquor of alkalinity potassium permanganate and phosphoric acid；
Step 2, the first mixed liquor through first membrane filtration removed into sediment, and to the first liquid storage box of lower tank
In be heated to 80 DEG C, and through the first atomization pipeline atomization；
The atomized liquid that step 3, step 2 are generated obtains just steaming vapor after heating through quartz plate；
Step 4, just steaming vapor enter indirect steam tank after the first spiral cold-finger, and by two in indirect steam tank
Secondary heating obtains the second vapor；
Obtain primary injection water after step 5, the second vapor are condensed, and it is dual through the second filter membrane and the 3rd filter membrane
Filtering, obtains secondary injection water；
Step 6, secondary injection water through Water quality detector detection it is qualified after, through 100 DEG C of flowing steam sterilization 25-
After 40min, the sterilized water for injection is produced.
In such scheme, by the chemical treatment to raw water, then filtering carries out indirect steam condensation, finally enters again
Row secondary fine filtering, filling sterilizing, whole preparation method is simply easily operated, and can be straight after the device of sterilized water for injection is prepared
Connect addition embedding and sterilizing installation, you can realize the Fully-automatic production line type production of sterilized water for injection, aquifer yield is big, and is made
Sterilized water for injection quality is high.Wherein, it can be removed by the alkalinity potassium permanganate added in raw water in annex solution, annex solution
Organic matter and carbon dioxide in raw water, and phosphoric acid can make the ammonia in raw water turn into nonvolatile ammonium salt, and then through first
Removed after membrane filtration.
Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed
With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art
Other modification is realized, therefore under the universal limited without departing substantially from claim and equivalency range, the present invention is not limited
In specific details and shown here as the legend with description.
Claims (10)
1. a kind of device for preparing sterilized water for injection, wherein, including：
Upper tank body, its top center is provided with the pipeline for protruding from the upper tank body upper surface, and the pipeline is being protruded on described
One end of tank surface is connected with Y tube, and the long end interface of the Y tube is connected with the pipeline, and another the two of the Y tube
End is respectively to be used for the raw water input port of raw water input and the annex solution input port for adding annex solution；Set in the upper tank body
Agitating device is equipped with, the agitating device includes rotary shaft and stirring vane, and the rotary shaft is vertically installed in the upper tank body
Inside, and the two ends of the upper tank body are fixed on, the rotary shaft is set to be hollow, and is communicated with the pipeline, the stirring
Blade is the hollow setting that another end opening is closed in one end, and the openend of the stirring vane is connected with rotary shaft, and with it is described
Perforate is provided with the inside connection of rotary shaft, the side of the stirring vane and top surface；
First filter, it includes the first filter cartridge and the first filter membrane, top and the upper tank body of first filter cartridge
Lower removable connection, and with the upper tank body fluid communication, first filter membrane is arranged at the inside of first filter cartridge,
And the inwall at the edge of first filter membrane and first filter cartridge fits；
Lower tank, its top is provided with the first liquid storage box, the side wall of first liquid storage box and bottom surface and is provided with the first heating
Plate, first liquid storage box is internally provided with the first temperature sensor being connected with first heating plate；First storage
The upper end of liquid box is connected with the lower removable of first filter cartridge, and the lower end of first liquid storage box connects the first mist pipe
Road, the first atomization pipeline is set for waveform, and the first atomization pipeline is in the direction towards the lower tank bottom surface
On be provided with the first atomization mouthful；Be provided with the bottom surface of the lower tank centered on the first quartz plate, first quartz plate to
The concave structure of lower protrusion, the bottom of first quartz plate is provided with primary heater；Set above the side wall of the lower tank
It is equipped with the first steam (vapor) outlet；
Indirect steam tank, its side wall is provided with steam inlet, and first steam (vapor) outlet is steamed by the first spiral cold-finger with described
Vapour entrance is connected, and the second liquid storage box, second liquid storage box are connected with the steam inlet in the indirect steam tank
Side wall and bottom surface on be provided with the second heating plate, being internally provided with for second liquid storage box is connected with second heating plate
Second temperature sensor；The lower end connection second of second liquid storage box is atomized pipeline, and the second atomization pipeline is wave
Shape is set, and the second atomization pipeline is provided with the second atomization mouthful on the direction towards the indirect steam tank bottom face；Institute
State and the second quartz plate is provided with the bottom surface of lower tank, downwardly projecting concave structure, described centered on second quartz plate
The bottom of second quartz plate is provided with secondary heater；The second steam (vapor) outlet is provided with above the side wall of the lower tank；
Second filter, it includes putting down on the second filter cartridge, the second filter membrane and the 3rd filter membrane, the inwall of second filter cartridge
Row is provided with 2 road necks, and second filter membrane and the 3rd filter membrane are respectively engaged with described in 2 roads in neck, the second filtering dress
The bottom for being placed in the indirect steam tank is installed, and is connected by the second spiral cold-finger with second steam (vapor) outlet；
Finished product collection device, it includes being provided with Water quality detector in detection tank, finished pot and three-way valve, the detection tank,
The Water quality detector is connected with the three-way valve, is gone out with each of three-way valve according to water quality detection output control
The opening and closing of liquid mouthful, and the detection tank is connected with the liquid outlet of second filter, two of the three-way valve go out
Liquid mouth connects finished pot and detection tank respectively, and another liquid outlet of the three-way valve is connected to the pipe by catheter
Road.
2. the device as claimed in claim 1 for preparing sterilized water for injection, wherein, in addition to：
Drive control mechanism, itself and the rotary shaft, the first temperature sensor, second temperature sensor, primary heater and
Two heaters are connected respectively.
3. the as claimed in claim 1 device for preparing sterilized water for injection, wherein, offered on the side wall of the upper tank body into
Air valve.
4. the device as claimed in claim 1 for preparing sterilized water for injection, wherein, set in lower tank and the indirect steam tank
It is equipped with pressure sensor, the side wall of lower tank and the indirect steam tank and is provided with urgent air bleeding valve, and the urgent exhaust
Valve is controlled by the pressure sensor.
5. the device as claimed in claim 1 for preparing sterilized water for injection, wherein, it is provided with check valve in the pipeline.
6. the as claimed in claim 1 device for preparing sterilized water for injection, wherein, first filter membrane, the second filter membrane and the
Three filter membranes are reverse osmosis filter membrane, and the aperture of first filter membrane is 0.4-0.5 μm, second filter membrane and the 3rd filter membrane
Aperture is 0.2-0.25 μm.
7. the device as claimed in claim 1 for preparing sterilized water for injection, wherein, the top of first filter is all provided with
Baffle plate is equipped with, the baffle plate is embedded in the groove of the upper tank body bottom, so as to the baffle plate is pulled, the upper tank body and first
Filter fluid communication.
8. the device as claimed in claim 1 for preparing sterilized water for injection, wherein, first spiral cold-finger and the second spiral shell
Rotation condenser pipe is integrally that inclined S-shaped is set, and first helix tube and the second helix tube connect one end of steam (vapor) outlet
Higher than the other end, meanwhile, the radian of the S-shaped of one end of the first helix tube and the second helix tube the connection steam (vapor) outlet is less than institute
State the radian of the other end of the first helix tube and the second helix tube；In addition, first spiral cold-finger and the condensation of the second spiral
Pipe is tool double-decker with dissection, and first spiral cold-finger and the second spiral cold-finger connect the one of steam (vapor) outlet
End is respectively arranged with cooling water intake, and the other end of first spiral cold-finger and the second spiral cold-finger is provided with cooling
Water delivery port, and the cooling water intake and cooling water outlet are connected to raw water input, so that shape in the interlayer
Into cooling water circulation.
9. the device as claimed in claim 1 for preparing sterilizing direct projection water, wherein, raw water enters by the raw water input port
It is preceding also to need by quartz sand and activated carbon filtering.
10. a kind of method that sterilized water for injection is prepared with the device for preparing sterilized water for injection as claimed in claim 1, its
In, comprise the following steps：
Step 1, at the two ends of the Y tube by the weight ratio of raw water and annex solution it is 1:0.003-0.005 each leads into raw water
And annex solution, mix and obtain the first mixed liquor；
Wherein, the annex solution is the mixed liquor of alkalinity potassium permanganate and phosphoric acid；
Step 2, by the first mixed liquor through first membrane filtration remove sediment, and into the first liquid storage box of lower tank plus
Heat is atomized to 80 DEG C, and through the first atomization pipeline；
The atomized liquid that step 3, step 2 are generated obtains just steaming vapor after heating through quartz plate；
Step 4, just steaming vapor enter indirect steam tank after the first spiral cold-finger, and are added in indirect steam tank by secondary
Heat obtains the second vapor；
Primary injection water, and the dual mistake through the second filter membrane and the 3rd filter membrane are obtained after step 5, the second vapor are condensed
Filter, obtains secondary injection water；
Step 6, secondary injection water through Water quality detector detection it is qualified after, after 100 DEG C of flowing steam sterilization 25-40min,
Produce the sterilized water for injection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710676347.1A CN107253795B (en) | 2017-08-09 | 2017-08-09 | Prepare the device and preparation method thereof of sterilized water for injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710676347.1A CN107253795B (en) | 2017-08-09 | 2017-08-09 | Prepare the device and preparation method thereof of sterilized water for injection |
Publications (2)
| Publication Number | Publication Date |
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| CN107253795A true CN107253795A (en) | 2017-10-17 |
| CN107253795B CN107253795B (en) | 2019-03-29 |
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| CN201710676347.1A Active CN107253795B (en) | 2017-08-09 | 2017-08-09 | Prepare the device and preparation method thereof of sterilized water for injection |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109293105A (en) * | 2018-08-28 | 2019-02-01 | 芜湖鸣人热能设备有限公司 | Heatable environmental protection purifier |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2782664Y (en) * | 2004-11-30 | 2006-05-24 | 浙江省医疗器械研究所 | Aseptic medical used injection water treatment equipment |
| CN202829637U (en) * | 2012-07-31 | 2013-03-27 | 湖北科伦药业有限公司 | Water for injection automatic preparation system |
| CN205635224U (en) * | 2016-05-19 | 2016-10-12 | 江西新天地药业有限公司 | Injection water water preparation system |
-
2017
- 2017-08-09 CN CN201710676347.1A patent/CN107253795B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2782664Y (en) * | 2004-11-30 | 2006-05-24 | 浙江省医疗器械研究所 | Aseptic medical used injection water treatment equipment |
| CN202829637U (en) * | 2012-07-31 | 2013-03-27 | 湖北科伦药业有限公司 | Water for injection automatic preparation system |
| CN205635224U (en) * | 2016-05-19 | 2016-10-12 | 江西新天地药业有限公司 | Injection water water preparation system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109293105A (en) * | 2018-08-28 | 2019-02-01 | 芜湖鸣人热能设备有限公司 | Heatable environmental protection purifier |
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| CN107253795B (en) | 2019-03-29 |
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