CN107252370A - A kind of joint prosthesis tibial tray and preparation method thereof - Google Patents

A kind of joint prosthesis tibial tray and preparation method thereof Download PDF

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Publication number
CN107252370A
CN107252370A CN201710027178.9A CN201710027178A CN107252370A CN 107252370 A CN107252370 A CN 107252370A CN 201710027178 A CN201710027178 A CN 201710027178A CN 107252370 A CN107252370 A CN 107252370A
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China
Prior art keywords
tibial tray
joint prosthesis
prosthesis tibial
preparation
hole
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Pending
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CN201710027178.9A
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Chinese (zh)
Inventor
吴栋
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Individual
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Individual
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Priority to CN201710027178.9A priority Critical patent/CN107252370A/en
Publication of CN107252370A publication Critical patent/CN107252370A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/38—Joints for elbows or knees
    • A61F2/389—Tibial components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30721—Accessories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772—Apertures or holes, e.g. of circular cross section
    • A61F2002/30784—Plurality of holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3093—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth for promoting ingrowth of bone tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Prostheses (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Manufacturing & Machinery (AREA)

Abstract

The invention discloses a kind of preparation method of joint prosthesis tibial tray, including：First generate hole or groove on joint prosthesis tibial tray body using various processing methods, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.Not only facilitate and lockmaking effect is formed between implant and bone tissue, the preferable space structure of offer can be grown into for new bone, be conducive to improving attachment, the Reproductive activity of bone and its cells, reach good synosteosis, joint prosthesis tibial tray and the amalgamation of autologous tissue are enhanced, is conducive to joint prosthesis tibial tray effectively to be played a role for a long time in human body；And excellent in mechanical performance, high mechanical strength, stress shielding can be reduced very well, keep Effective Mechanical Properties support.

Description

A kind of joint prosthesis tibial tray and preparation method thereof
Technical field
The present invention relates to technical field of medical instruments, more particularly to a kind of orthopaedics implant joint prosthesis tibial tray and its system Preparation Method.
Background technology
The joint prosthesis disease caused by disease and wound is common disease clinically, is also the worldwide difficulty of orthopaedics therapy One of topic, severely impacts the quality of life of patient.Joint prosthesis tibial tray is current clinical practice more universal orthopaedics Use material.Extensive use of the joint prosthesis tibial tray in orthopaedics therapy, significantly improves over clinical insurmountable problem And it is implanted to power and has also reached quite satisfied effect.Or existing joint prosthesis tibial tray is using increasing material manufacturing skill Art forms certain mat surface on joint prosthesis tibial tray body, or using subtracting material manufacturing technology in joint prosthesis tibial tray The structures such as hole are generated on body, but using increases material manufacturing technology or subtract joint prosthesis shin bone prepared by material manufacturing technology merely Bone Ingrowth effect between disk and bone is bad, it is unstable to merge insufficient, long-term fixed effect, and operative failure is caused when serious Or postoperative rehabilitation is bad.
The content of the invention
The technical problems to be solved by the invention are to overcome the defect of above-mentioned prior art there is provided a kind of joint prosthesis shin bone Disk and preparation method thereof, makes joint prosthesis tibial tray strong with patient's sclerotin adhesion, is conducive to bone tissue to grow into, and can be achieved more excellent Biology fixed effect.
The technical problems to be solved by the invention are achieved by the following technical programs：
A kind of preparation method of joint prosthesis tibial tray, including：First using various processing methods in joint prosthesis tibial tray body Upper generation hole or groove, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
Further, the aperture in the hole is 50-10000 μm, and depth is 25-5000 μm；A width of 50-10000 μ of the groove M, depth is 25-5000 μm.
Further, the post is prominent, ball is prominent or other three-dimensional shapes a height of 2-6000 μm, forms mat surface, is conducive to Gegenbaur's cell creeping with it is fixed.
Further, the increases material manufacturing technology is 3D printing.
Further, the joint prosthesis tibial tray body by the metal material vacuum lost wax casting of biocompatibility or Forging is made.
Further, the Surface Creation hole at joint prosthesis tibial tray body Yu human body bone Long Term Contact position or groove.
The present invention also provides a kind of joint prosthesis tibial tray, is made of described preparation method.
The present invention has the advantages that：
（1）The present invention first life on joint prosthesis tibial tray body using various processing methods on joint prosthesis tibial tray body Pore-forming or groove, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove, combine and subtract material system The advantage of technology and increases material manufacturing technology is made, it is and traditional compared to traditional only with material manufacturing technology generation hole is subtracted Only with increases material manufacturing technology formation mat surface, the surface area of joint prosthesis tibial tray and synosteosis increases 5-10 times, does not only have Help form lockmaking effect between joint prosthesis tibial tray and bone tissue, the preferable space knot of offer can be grown into for new bone Structure, is conducive to improving attachment, the Reproductive activity of bone and its cells, reaches good synosteosis, enhance joint prosthesis tibial tray With the amalgamation of autologous tissue, joint prosthesis tibial tray is conducive to effectively to be played a role for a long time in human body；And mechanical property Excellent, the high mechanical strength of energy, stress shielding can be reduced very well, keep Effective Mechanical Properties support.
（2）Process is simple, controllability is strong, easy to operate.
Brief description of the drawings
Fig. 1 is top view of the invention；
Fig. 2 is side view of the invention.
In figure：1st, joint prosthesis tibial tray body, 2, hole, 3, post dashes forward.
Embodiment
With reference to embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention, It is not limitation of the invention.
In the preparation method of the joint prosthesis tibial tray of the present invention, first using various processing methods in joint prosthesis tibial tray Generate hole or groove on body, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
The various processing methods be known in the art it is any can be generated on joint prosthesis tibial tray body hole or The processing method of groove, such as casting, forging, lf, acid corrosion.
The increases material manufacturing technology is preferred but is not limited to 3D printing.
The joint prosthesis tibial tray body is preferred but is not limited to dewax by the metal material vacuum of biocompatibility Casting or forging are made, and wherein the metal material of biocompatibility is preferred but is not limited to titanium alloy, cochrome, and wherein titanium is closed Gold includes Ti-8Fe-8Ta-4Zr, and Ti-8Fe-8Ta-4Zr greatly reduces modulus of elasticity compared to traditional titanium alloy, can be with Obtain the excellent results in terms of engineering properties and biocompatibility.
Embodiment 1
A kind of joint prosthesis tibial tray, its preparation method includes：By titanium alloy using vacuum lost wax casting or forging manufacturer Work joint tibial tray body, is then connect for a long time using lf method in the joint prosthesis tibial tray body with human body bone Generation hole or groove on the surface of contact portion position, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；The laser Melting method uses prior art, and the aperture for making hole is 50 μm, and depth is 25 μm, makes a width of 50 μm of groove, and depth is 25 μm；The 3d is beaten Print technology uses prior art, makes that post is prominent, ball is prominent or other three-dimensional shapes a height of 2 μm.
Embodiment 2
A kind of joint prosthesis tibial tray, its preparation method includes：By titanium alloy using vacuum lost wax casting or forging manufacturer Work joint tibial tray body, is then connect for a long time using lf method in the joint prosthesis tibial tray body with human body bone Generation hole or groove on the surface of contact portion position, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；The laser Melting method uses prior art, and the aperture for making hole is 10000 μm, and depth is 5000 μm, makes a width of 10000 μm of groove, depth is 5000μm；The 3d printing techniques use prior art, make that post is prominent, ball is prominent or other three-dimensional shapes a height of 6000 μm.
Embodiment 3
A kind of joint prosthesis tibial tray, its preparation method includes：By titanium alloy using vacuum lost wax casting or forging manufacturer Work joint tibial tray body, is then connect for a long time using lf method in the joint prosthesis tibial tray body with human body bone Generation hole or groove on the surface of contact portion position, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；The laser Melting method uses prior art, and the aperture for making hole is 1000 μm, and depth is 1000 μm, makes a width of 1000 μm of groove, and depth is 3000 μ m；The 3d printing techniques use prior art, make that post is prominent, ball is prominent or other three-dimensional shapes a height of 500 μm.
Embodiment 4
A kind of joint prosthesis tibial tray, its preparation method includes：By titanium alloy using vacuum lost wax casting or forging manufacturer Work joint tibial tray body, then using acid corrosion method used in the joint prosthesis tibial tray body and human body bone Long Term Contact Generate hole or groove on the surface at position, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；The sour Losing operation is：Joint prosthesis tibial tray body is first 15% hydrofluoric acid treatment 5-60 second with concentration, is then 65% with concentration Nitric acid is handled 1-10 minutes at 75 DEG C, then then takes out utilization in being handled 1-5 minutes at 70 DEG C with the hydrochloric acid that concentration is 36% Distilled water or deionized water are cleaned；The aperture in the hole is 100-6000 μm, and depth is 500-3000 μm；The groove it is a width of 500-3000 μm, depth is that the 100-2000 μm of 3d printing technique uses prior art, makes that post is prominent, ball is prominent or other three-dimensional shapes A height of 2000 μm.
Comparative example 1
A kind of joint prosthesis tibial tray, its preparation method is：By titanium alloy using vacuum lost wax casting or forging manufacture of intraocular Joint tibial tray body.
Comparative example 2
A kind of joint prosthesis tibial tray, its preparation method includes：By titanium alloy using vacuum lost wax casting or forging manufacturer Work joint tibial tray body, is then connect for a long time using lf method in the joint prosthesis tibial tray body with human body bone Multiple holes are generated on the surface of contact portion position；The aperture in the hole is 50-10000 μm, and depth is 25-5000 μm.
Detection project：
A. BGP generation test
MC3T3-E1 Gegenbaur's cells derive from the skull of newborn mice, and cell culture medium is cultivated for α-MEM
Base, wherein containing 10% hyclone, 100U/ml green grass or young crops/streptomysin, 0.05g/L ascorbic acid and 10mmol/L β- Sodium glycero-phosphate.The embodiment 1-4 and comparative example 1-2 orthopaedics implants prepared are respectively put into 24 orifice plates, using 70% second Alcohol sterilizing is stayed overnight, and is washed 3 times with phosphate buffer (PBS), and is sterilized 2 hours with ultraviolet irradiation.Experiment is in the every of 24 orifice plates Hole inoculation 105Individual cell, keeping temperature is 37 DEG C, contains 5% CO2 in atmosphere, continues to collect supernatant after cultivating 14 days, uses The content of BGP in BGP ELISA kit detection supernatant.Unit：ng/mL.
B. tensile strength
According to GB/T 13810-2007, tension is carried out to joint prosthesis tibial tray prepared by embodiment 1-4 and comparative example 1-3 strong Degree test.Unit：Rm/MPa.
Embodiment described above only expresses embodiments of the present invention, and it describes more specific and detailed, but can not Therefore the limitation to the scope of the claims of the present invention is interpreted as, as long as the skill obtained using the form of equivalent substitution or equivalent transformation Art scheme, all should fall within the scope and spirit of the invention.

Claims (5)

1. a kind of preparation method of joint prosthesis tibial tray, it is characterised in that including：First manually closed using various processing methods Save generation hole or groove on tibial tray body, then builds using increases material manufacturing technology that post is prominent, ball is prominent or other solids in hole or groove Shape.
2. the preparation method of joint prosthesis tibial tray as claimed in claim 1, it is characterised in that the aperture in the hole is 50- 10000 μm, depth is 25-5000 μm；A width of 50-10000 μm of the groove, depth is 25-5000 μm.
3. the preparation method of joint prosthesis tibial tray as claimed in claim 1, it is characterised in that the post is prominent, ball is prominent or it A height of 2-6000 μm of his three-dimensional shape.
4. the preparation method of joint prosthesis tibial tray as claimed in claim 1, it is characterised in that the joint prosthesis tibial tray Body is made up of the metal material vacuum lost wax casting or forging of biocompatibility.
5. a kind of joint prosthesis tibial tray, is made of the preparation method described in claim any one of 1-4.
CN201710027178.9A 2017-01-16 2017-01-16 A kind of joint prosthesis tibial tray and preparation method thereof Pending CN107252370A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710027178.9A CN107252370A (en) 2017-01-16 2017-01-16 A kind of joint prosthesis tibial tray and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201710027178.9A CN107252370A (en) 2017-01-16 2017-01-16 A kind of joint prosthesis tibial tray and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107252370A true CN107252370A (en) 2017-10-17

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Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110899587A (en) * 2019-12-03 2020-03-24 无锡航亚科技股份有限公司 Forging forming method of precise tibial plateau artificial joint implant

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1170561A (en) * 1996-04-10 1998-01-21 苏舍奥索帕迪有限公司 Metal implant with surface and method for producing the surface
CN105105886A (en) * 2015-07-29 2015-12-02 深圳市义和平有限公司 Improved artificial knee joint tibial tray with porous film and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1170561A (en) * 1996-04-10 1998-01-21 苏舍奥索帕迪有限公司 Metal implant with surface and method for producing the surface
CN105105886A (en) * 2015-07-29 2015-12-02 深圳市义和平有限公司 Improved artificial knee joint tibial tray with porous film and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110899587A (en) * 2019-12-03 2020-03-24 无锡航亚科技股份有限公司 Forging forming method of precise tibial plateau artificial joint implant
CN110899587B (en) * 2019-12-03 2020-11-20 无锡航亚科技股份有限公司 Forging forming method of precise tibial plateau artificial joint implant

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