CN107252358A - A kind of tooth implant and preparation method thereof - Google Patents
A kind of tooth implant and preparation method thereof Download PDFInfo
- Publication number
- CN107252358A CN107252358A CN201710032127.5A CN201710032127A CN107252358A CN 107252358 A CN107252358 A CN 107252358A CN 201710032127 A CN201710032127 A CN 201710032127A CN 107252358 A CN107252358 A CN 107252358A
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- China
- Prior art keywords
- tooth implant
- hole
- preparation
- groove
- prominent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0037—Details of the shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0037—Details of the shape
- A61C2008/0046—Textured surface, e.g. roughness, microstructure
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- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of preparation method of tooth implant, including：First generate hole or groove on tooth implant body using various processing methods, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.Not only facilitate and lockmaking effect is formed between implant and bone tissue, the preferable space structure of offer can be grown into for new bone, be conducive to improving attachment, the Reproductive activity of bone and its cells, reach good synosteosis, tooth implant and the amalgamation of autologous tissue are enhanced, is conducive to tooth implant effectively to be played a role for a long time in human body；And excellent in mechanical performance, high mechanical strength, stress shielding can be reduced very well, keep Effective Mechanical Properties support.
Description
Technical field
The present invention relates to technical field of medical instruments, more particularly to a kind of dental implant tooth implant and its preparation side
Method.
Background technology
Tooth implant is current clinical practice more universal dental material.Tooth implant is extensive in dental treatment
Using significantly improving over and clinical insurmountable problem and be implanted to power and also reached quite satisfied effect.
Or existing tooth implant forms certain mat surface using increases material manufacturing technology on tooth implant body, or using subtracting
Material manufacturing technology generates the structures such as hole on tooth implant body, but using increases material manufacturing technology or subtracts material manufacture skill merely
Bone Ingrowth effect between tooth implant and bone prepared by art is bad, it is unstable to merge insufficient, long-term fixed effect, seriously
Shi Zaocheng operative failures or postoperative rehabilitation are bad.
The content of the invention
The technical problems to be solved by the invention be overcome the defect of above-mentioned prior art there is provided a kind of tooth implant and its
Preparation method, makes tooth implant strong with patient's sclerotin adhesion, is conducive to bone tissue to grow into, and preferably biology can be achieved and fixes
Effect.
The technical problems to be solved by the invention are achieved by the following technical programs：
A kind of preparation method of tooth implant, including：Hole or groove are first generated on tooth implant body using various processing methods,
Using increases material manufacturing technology to be built in hole or groove again, post is dashed forward, ball is dashed forward or other three-dimensional shapes.
Further, the aperture in the hole is 5-2500 μm, and depth is 0.5-1000 μm；A width of 5-2500 μm of the groove,
Depth is 0.5-1000 μm.
Further, the post is prominent, ball is prominent or other three-dimensional shapes a height of 0.1-1100 μm, forms mat surface, favorably
In creeping with fixing for Gegenbaur's cell.
Further, the increases material manufacturing technology is 3D printing.
Further, the tooth implant body is made up of the metal material forging of biocompatibility.
Further, the Surface Creation hole at tooth implant body Yu human body bone Long Term Contact position or groove.
The present invention also provides a kind of tooth implant, is made of described preparation method.
The present invention has the advantages that：
（1）The present invention first generates hole or groove using various processing methods on tooth implant body on tooth implant body, then
Build in hole or groove that post is prominent, ball is prominent or other three-dimensional shapes using increases material manufacturing technology, combine and subtract material manufacturing technology and increasing
Material manufacturing technology is and traditional only with increasing material manufacturing skill compared to traditional only with material manufacturing technology generation hole is subtracted
Art formation mat surface, the surface area of tooth implant and synosteosis increases 5-10 times, not only facilitate tooth implant and bone tissue it
Between form lockmaking effect, the preferable space structure of offer can be grown into for new bone, be conducive to improving the attachment of bone and its cells,
Reproductive activity, reaches good synosteosis, enhances tooth implant and the amalgamation of autologous tissue, is conducive to tooth implant in people
Effectively played a role for a long time in body；And excellent in mechanical performance, high mechanical strength, stress shielding can be reduced very well, kept
Effective Mechanical Properties are supported.
（2）Process is simple, controllability is strong, easy to operate.
Brief description of the drawings
Fig. 1 is top view of the invention.
Fig. 2 is side view of the invention.
In figure：1st, tooth implant body, 2, hole, 3, post dashes forward.
Embodiment
With reference to embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention,
It is not limitation of the invention.
In the preparation method of the tooth implant of the present invention, first hole is generated on tooth implant body using various processing methods
Or groove, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
The various processing methods be known in the art it is any can be generated on tooth implant body hole or groove plus
Work method, such as casting, forging, lf, acid corrosion.
The increases material manufacturing technology is preferred but is not limited to 3D printing.
The tooth implant body is preferred but is not limited to be made up of the metal material forging of biocompatibility, wherein raw
The metal material of thing compatibility is preferred but is not limited to pure titanium, titanium alloy, cochrome, and wherein titanium alloy includes Ti-8Fe-
8Ta-4Zr, Ti-8Fe-8Ta-4Zr greatly reduce modulus of elasticity compared to traditional titanium alloy, can obtain in mechanicalness
Excellent results in terms of matter and biocompatibility.
Embodiment 1
A kind of tooth implant, its preparation method includes：By pure titanium using forging manufacture tooth implant body, then using laser
Melting method generates hole or groove on the surface at the tooth implant body Yu human body bone Long Term Contact position, then is beaten using 3D
It is imprinted in hole and builds that post is prominent, ball is prominent or other three-dimensional shapes；The lf method uses prior art, and the aperture for making hole is 5 μ
M, depth is 0.5 μm, makes a width of 5 μm of groove, and depth is 0.5 μm；The 3d printing techniques use prior art, post is dashed forward, ball is dashed forward or it
A height of 0.1 μm of his three-dimensional shape.
Embodiment 2
A kind of tooth implant, its preparation method includes：Tooth implant body is manufactured using forging machine by pure titanium, then using sharp
Light melting method generates hole or groove on the surface at the tooth implant body Yu human body bone Long Term Contact position, then using 3D
It is printed upon in hole and builds that post is prominent, ball is prominent or other three-dimensional shapes；The lf method uses prior art, and the aperture for making hole is
100 μm, depth is 20 μm, makes a width of 100 μm of groove, and depth is 20 μm；The 3d printing techniques use prior art, post is dashed forward, ball is dashed forward
Or a height of 25 μm of other three-dimensional shapes.
Embodiment 3
A kind of tooth implant, its preparation method includes：By pure titanium using forging manufacture tooth implant body, then using laser
Melting method generates hole or groove on the surface at the tooth implant body Yu human body bone Long Term Contact position, then is beaten using 3D
It is imprinted in hole and builds that post is prominent, ball is prominent or other three-dimensional shapes；The lf method uses prior art, and the aperture for making hole is 50
μm, depth is 10 μm, makes a width of 50 μm of groove, and depth is 10 μm；The 3d printing techniques use prior art, post is dashed forward, ball is dashed forward or it
A height of 15 μm of his three-dimensional shape.
Embodiment 4
A kind of tooth implant, its preparation method includes：By pure titanium using forging manufacture tooth implant body, then using sour
Etching method generates hole or groove on the surface at the tooth implant body Yu human body bone Long Term Contact position, then using 3D printing
Structure post is dashed forward in hole, ball is dashed forward or other three-dimensional shapes；The acid corrosion is operated：Tooth implant body is first 15% with concentration
Hydrofluoric acid treatment 5-60 seconds, then handle 1-10 minutes at 75 DEG C for 65% nitric acid with concentration, then with concentration be 36%
Hydrochloric acid is then taken out and cleaned using distilled water or deionized water in being handled 1-5 minutes at 70 DEG C；The aperture in the hole is
20-40 μm, depth is 5-10 μm；A width of 20-40 μm of the groove, depth is 5-10 μm, and the 3d printing techniques use prior art, make
Post is prominent, ball is prominent or other three-dimensional shapes a height of 0.5-15 μm.
Comparative example 1
A kind of tooth implant, its preparation method is：By pure titanium using forging manufacture tooth implant body.
Comparative example 2
A kind of tooth implant, its preparation method includes：By pure titanium using forging manufacture tooth implant body, then using laser
Melting method generates multiple holes on the surface at the tooth implant body Yu human body bone Long Term Contact position；The hole in the hole
Footpath is 5-100 μm, and depth is 0.5-20 μm.
Detection project：
A. BGP generation test
MC3T3-E1 Gegenbaur's cells derive from the skull of newborn mice, and cell culture medium is cultivated for α-MEM
Base, wherein containing 10% hyclone, 100U/ml green grass or young crops/streptomysin, 0.05g/L ascorbic acid and 10mmol/L β-
Sodium glycero-phosphate.
The embodiment 1-4 and comparative example 1-2 dental implants prepared are respectively put into 24 orifice plates, sterilized using 70% ethanol
Overnight, washed 3 times, and sterilized 2 hours with ultraviolet irradiation with phosphate buffer (PBS).Test and be inoculated with every hole of 24 orifice plates
105Individual cell, keeping temperature is 37 DEG C, contains 5% CO2 in atmosphere, continues to collect supernatant after cultivating 14 days, uses BGP
The content of BGP in ELISA kit detection supernatant.Unit：ng/mL.
B. tensile strength
According to GB/T 13810-2007, tensile strength test is carried out to tooth implant prepared by embodiment 1-4 and comparative example 1-3.
Unit：Rm/MPa.
Embodiment described above only expresses embodiments of the present invention, therefore it describes more specific and detailed, but can not be
And the limitation to the scope of the claims of the present invention is interpreted as, as long as the technical side obtained using the form of equivalent substitution or equivalent transformation
Case, all should fall within the scope and spirit of the invention.
Claims (5)
1. a kind of preparation method of tooth implant, it is characterised in that including：First using various processing methods in tooth implant body
Upper generation hole or groove, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
2. the preparation method of tooth implant as claimed in claim 1, it is characterised in that the aperture in the hole is 5-2500 μm,
Depth is 0.5-1000 μm；A width of 5-2500 μm of the groove, depth is 0.5-1000 μm.
3. the preparation method of tooth implant as claimed in claim 1, it is characterised in that the post is prominent, ball is prominent or other are three-dimensional
A height of 0.1-1100 μm of shape.
4. the preparation method of tooth implant as claimed in claim 1, it is characterised in that the tooth implant body passes through biology
The metal material forging of compatibility is made.
5. a kind of tooth implant, is made of the preparation method described in claim any one of 1-4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710032127.5A CN107252358A (en) | 2017-01-17 | 2017-01-17 | A kind of tooth implant and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710032127.5A CN107252358A (en) | 2017-01-17 | 2017-01-17 | A kind of tooth implant and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN107252358A true CN107252358A (en) | 2017-10-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710032127.5A Pending CN107252358A (en) | 2017-01-17 | 2017-01-17 | A kind of tooth implant and preparation method thereof |
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| CN (1) | CN107252358A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114005324A (en) * | 2021-11-11 | 2022-02-01 | 深圳市人民医院 | Oral implantation operation training device and using method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101653384A (en) * | 2009-07-30 | 2010-02-24 | 上海交通大学 | Dental implant of surface nano-structure and manufacturing method thereof |
| US20160058530A1 (en) * | 2013-05-07 | 2016-03-03 | Altimed International Sa | Dental Implant Having Porous Structure |
| US20160143709A1 (en) * | 2013-07-18 | 2016-05-26 | Osstemimplant Co., Ltd. | Implant coating material for enhancing a bioactivity and osseointegration of implant surface, and the method for manufacturing and storing the same |
| US20160250008A1 (en) * | 2013-10-15 | 2016-09-01 | Nobel Biocare Services Ag | Dental implant replica |
-
2017
- 2017-01-17 CN CN201710032127.5A patent/CN107252358A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101653384A (en) * | 2009-07-30 | 2010-02-24 | 上海交通大学 | Dental implant of surface nano-structure and manufacturing method thereof |
| US20160058530A1 (en) * | 2013-05-07 | 2016-03-03 | Altimed International Sa | Dental Implant Having Porous Structure |
| US20160143709A1 (en) * | 2013-07-18 | 2016-05-26 | Osstemimplant Co., Ltd. | Implant coating material for enhancing a bioactivity and osseointegration of implant surface, and the method for manufacturing and storing the same |
| US20160250008A1 (en) * | 2013-10-15 | 2016-09-01 | Nobel Biocare Services Ag | Dental implant replica |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114005324A (en) * | 2021-11-11 | 2022-02-01 | 深圳市人民医院 | Oral implantation operation training device and using method thereof |
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Application publication date: 20171017 |