CN107224429A - 一种安全性高的左旋奥硝唑注射液及其制备方法 - Google Patents
一种安全性高的左旋奥硝唑注射液及其制备方法 Download PDFInfo
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- CN107224429A CN107224429A CN201710475241.5A CN201710475241A CN107224429A CN 107224429 A CN107224429 A CN 107224429A CN 201710475241 A CN201710475241 A CN 201710475241A CN 107224429 A CN107224429 A CN 107224429A
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- ornidazole
- acetate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Biochemistry (AREA)
- Dermatology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710475241.5A CN107224429B (zh) | 2017-06-21 | 2017-06-21 | 一种安全性高的左旋奥硝唑注射液及其制备方法 |
Applications Claiming Priority (1)
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CN201710475241.5A CN107224429B (zh) | 2017-06-21 | 2017-06-21 | 一种安全性高的左旋奥硝唑注射液及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN107224429A true CN107224429A (zh) | 2017-10-03 |
CN107224429B CN107224429B (zh) | 2019-04-05 |
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CN201710475241.5A Active CN107224429B (zh) | 2017-06-21 | 2017-06-21 | 一种安全性高的左旋奥硝唑注射液及其制备方法 |
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CN (1) | CN107224429B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1686117A (zh) * | 2005-04-28 | 2005-10-26 | 南京圣和药业有限公司 | 左旋奥硝唑在制备抗厌氧菌感染药物的应用 |
CN1686116A (zh) * | 2005-04-29 | 2005-10-26 | 南京圣和药业有限公司 | 左旋奥硝唑的静脉给药制剂及其制备方法 |
CN1739505A (zh) * | 2005-09-19 | 2006-03-01 | 扬子江药业集团有限公司 | 一种左旋奥硝唑注射制剂 |
CN101817786A (zh) * | 2010-04-13 | 2010-09-01 | 陕西合成药业有限公司 | 一种左旋奥硝唑的制备方法 |
-
2017
- 2017-06-21 CN CN201710475241.5A patent/CN107224429B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1686117A (zh) * | 2005-04-28 | 2005-10-26 | 南京圣和药业有限公司 | 左旋奥硝唑在制备抗厌氧菌感染药物的应用 |
CN1686116A (zh) * | 2005-04-29 | 2005-10-26 | 南京圣和药业有限公司 | 左旋奥硝唑的静脉给药制剂及其制备方法 |
CN1739505A (zh) * | 2005-09-19 | 2006-03-01 | 扬子江药业集团有限公司 | 一种左旋奥硝唑注射制剂 |
CN101817786A (zh) * | 2010-04-13 | 2010-09-01 | 陕西合成药业有限公司 | 一种左旋奥硝唑的制备方法 |
Non-Patent Citations (1)
Title |
---|
黄建权等: "高效液相色谱法测定左旋奥硝唑原料药中右旋异构体杂质", 《创新药物及新品种研究、开发学术研讨会论文集》 * |
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CN107224429B (zh) | 2019-04-05 |
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Inventor after: Cao Feng Inventor after: Tang Kaitian Inventor after: Cheng Fang Inventor after: Sun Yong Inventor after: Xu Yan Inventor before: Cao Feng Inventor before: Tang Kaitian Inventor before: Cheng Fang Inventor before: Sun Yong |
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Effective date of registration: 20190115 Address after: 116023 Jinyuxinghai 2-1-10-1, No. 588 Zhongshan Road, Shahekou District, Dalian City, Liaoning Province Applicant after: Dalian ZHONGXIN PHARMACEUTICAL Limited by Share Ltd Applicant after: Jiangsu Lixin Medical Technology Co., Ltd. Applicant after: HUNAN WARRANT PHARMACEUTICAL CO., LTD. Address before: 116023 Jinyuxinghai 2-1-10-1, No. 588 Zhongshan Road, Shahekou District, Dalian City, Liaoning Province Applicant before: Dalian ZHONGXIN PHARMACEUTICAL Limited by Share Ltd Applicant before: Jiangsu Lixin Medical Technology Co., Ltd. |
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