The drug storage of nebulizer administration and atomising device
Technical field
The invention belongs to nebulizer administration field, the drug storage of more particularly to a kind of nebulizer administration and atomization dress
Put.
Background technology
Inhalation in Treating plays weight in terms of breathing problem such as asthma, chronic obstructive pulmonary disease and respiratory tract infection is mitigated
Act on, for the treatment of specified disease, inhalation has more advantage than other administering modes, particularly some are easily in enteron aisle
In the macromolecular drug that is degraded, is influenceed by liver first-pass effect, be more suitable for the breathing area that lung is reached by inhalation.
The method that inhalation has three kinds of inhalations at present:Dosage metered dose inhaler(MDI), Foradil Aerolizer formoterol fumarate(DPI)And atomizer
(nebulizer).Wherein, nebulizer administration is due to atomizing effect is good, easy to operate, noise is small, small volume is portable etc.
Advantage, its clinical practice is more and more extensive.
Atomisation administration is, due to atomizing effect, operability, it is portable in terms of there is unique advantage and enjoy pass
Note, is widely used in the various breathing problems for the treatment of even other systems disease in clinic.Atomizer is to use liquid spray
Form medicine drop is delivered to the device of lung, drug solution or suspension are broken using oxygen, compressed air or ultrasonic method
The balance at liquid interface, with reference to specific atomizing component and structure design, promotes medical liquid atomizing to form small liquid particles(It is so-called
" mist "), respiratory tract and lung are sucked by suction nozzle.
Neulized inhalation compares other administering modes, mainly has the advantage that:(1)The medicine of suction can be directly to up to respiratory tract
And lung, blood is directly entered through pulmonary capillary, thus it is more rapid-action than oral drugs, and more effectively;(2)Due to medicine
Directly enter respiratory tract through suction, and be directly entered blood through pulmonary capillary, it is to avoid the first pass effect of liver, its consumption is most
/ 10th of many other administering modes of need, it will be apparent that reduce the toxic side effect of medicine, this point is for children and old man
It is particularly important;(3)Humidifying airway, dilutes sputum, can be commonly used to various breathing problems;(4)For some with virus sense
It is based on dye, can self-healing disease(As caught a cold), atomization inspiration treatment can substantially mitigate symptom, shorten the course of disease;(5)Medicine is acted on
Directly, it is rapid-action, it is significantly and rapid to alleviating bronchial astehma effect, better than other treatment mode, or even in clutch energy
Enough save the life of patient.
The target of atomization inspiration treatment be by the medicine of therapeutic dose in the way of atomizing particle in the relatively short time(It is logical
It is often 5-15 minutes)Interior importing respiratory tract or lung.In atomization process, the medicine glass of specific volume is used as receiving drug solution
Container, after container privileged site is opened, decoction is contacted with atomizing piece, realizes the high-efficient atomizing to decoction.With enteron aisle or other are non-
Intestinal canal administration is compared, and has many advantages by nebulizer administration:Quick acting, reduces therapeutic dose reduction toxic side effect
Deng, therefore clinical or residential care is now widely used in, it is used as the therapeutic administratp mode of specified disease.
Atomized inhalation includes various solution or liquid suspension dosage form, and specific auxiliary material is added in medicine to realize that medicine is controlled
The target for the treatment of.Atomized solns or suspension all at present is all sterile, and majority is dispensed in the form of unit dosage,
Avoid the pollution of antibiotic or microorganism.One typical suction atomizer product includes soup holding device(Atomizing cup), gear
Plate, the main frame containing atomizing piece(Or compression set), suction nozzle or mask etc..
At present, in the atomization system of clinical or family expenses, atomizing piece is used as the atomization non-removable part of main frame,
Decoction is put into atomizing cup when using, atomizing piece is contacted with liquid medicine, is realized and be atomized by compression or ultrasonic technique.So
It is necessary to be cleaned to atomizing piece after being often administered once, excessive cleaning step is not only made troubles to user, can also be increased
The loss of atomising device, accelerates the aging of atomizing piece, once atomising device or atomizing piece are out of order, will face whole atomizer
Abandon.Meanwhile, atomizing piece is exposed in environment for a long time as a component of atomizer, easily by bacterium, fungi, anti-
The pollution of the various harmful substances such as raw element, even if also can not thoroughly be cleared the pollution off by sterilization, this is to requiring sterile medicine
The atomization of solution is very unfavorable.In addition, being atomized using conventional atomizers to medicine, different pharmaceutical easily produces friendship when treating
Fork pollution, largely effects on the therapeutic effect of disease.
The content of the invention
On the premise of considering each side factor, the present invention proposes the drug storage and atomization of a kind of nebulizer administration
Device, its be not required to atomization part clean, can integral replacing without being impacted to atomization plant main frame.
The technical solution adopted by the present invention is as follows:
A kind of drug storage of nebulizer administration and atomising device, including:
Medicine glass module, it includes offering and the cavity phase on the medicine glass with the cavity for holding decoction, the medicine glass
Logical atomization mouthful;
Module is atomized, it includes being used for the atomization part of medical liquid atomizing;
Isolated part, it, which is located between the atomization mouth and the atomization module, is used to allow decoction to contact only in atomized medicine introducing
The atomization part;
Wherein, the drug storage and atomising device have atomized medicine introducing state, and in atomized medicine introducing state, the isolated part is taken out
From, remove or destroy, decoction and atomization part contact in the medicine glass,
The medicine glass module also includes the first connecting portion part for being used to connect atomization plant main frame;The atomization module also includes using
In connection atomizing face mask or the second connecting portion part of suction nozzle.
Preferably, one or more of the isolated part in cap, encapsulating film and membrane layer;Wherein:
The cap is connected on the wall of cup of the medicine glass to close the atomization mouth, and the cap has by outer
The weak point being broken after power;
The encapsulating film can be pulled out, crimp or be arranged on puncturing between the medicine glass and the atomization module or described
On medicine glass or on the atomization module;
The membrane layer covers to be formed on the atomization part and can be destroyed or remove.
Preferably, the part that is atomized is distributed with substantial amounts of micro- for piezoelectric ceramic atomizer patch on the piezoelectric ceramic atomizer patch
Hole.
It is used for it is highly preferred that the first connecting portion part includes at least one pair of and the atomization plant main frame connects to obtain
The access probe of electric signal.
Further, at least one pair of the first conductive spy of the medicine glass provided with electrical connection corresponding with the access probe
Pin, the atomization module includes at least one pair of second conducting probe that electric signal is provided to the piezoelectric ceramic atomizer patch, works as institute
Atomized medicine introducing device is stated in atomized medicine introducing state, first conducting probe and second conducting probe connect.
Further, it is described atomization module include to the piezoelectric ceramic atomizer patch provide electric signal at least one pair of second
Conducting probe, when the atomized medicine introducing device is in atomized medicine introducing state, the access electric probe passes through wire and described second
Conducting probe connects.
Preferably, there is at least one circle to outward extend flange, the flange surrounds the mist on the outer wall of the medicine glass
Change mouth to set, the isolated part is arranged on the flange.
It is highly preferred that the flange includes inward flange and outward flange, the inward flange is set around the atomization mouth, described
Outward flange is set around the inward flange, and the isolated part includes cap and encapsulating film, and the cap is arranged on described
On inward flange and the cap has the weak point that is broken after by external force, the encapsulating film is arranged on the outward flange
And can be punctured or crimp.
Preferably, the second connecting portion part includes atomizing face mask seat.
Preferably, it is further opened with air-vent on the medicine glass, the medicine glass, which is provided with, to be used to closing the air-vent and can
It is removed and exposes the medicine glass cap of the air-vent.
Medicine glass module of the present invention and atomization module, both are combined with each other into a kind of dress being atomized to drug solution
Put.The atomization mouth of medicine glass removes encapsulating film and cap, and atomization module removes after atomization module bottom, and both are mutually butted, and make
Decoction in medicine glass is fully contacted with atomizing piece.After the atomization plant main frame without atomizing piece is connected, various sides can be passed through
Method driving atomization, the including but not limited to means such as injection, mesh or ultrasound, realize the atomization to decoction.It is preferred that, the medicine glass
Module is independent component with atomization module, is atomized using preceding by being realized after slitless connection to decoction.It is further preferred that institute
The atomization driving force for stating atomization module is atomized for mesh.
Medicine glass module of the present invention, its body shape can be cylindrical, conical, cube shaped or by specific
Face and the enclosed construction of side composition, pref. cylindrical structure.The atomization mouth position of medicine glass is the side or bottom on medicine glass surface
Portion.It is preferred that, atomization mouth is located at the side wall of medicine glass, is circular prominent structure.There is atomization mouth envelope in the middle part of the medicine glass atomization mouth
Capping, atomization mouth outside portion is that medicine glass is atomized mouth encapsulating film.Medicine glass atomization mouth can also be located at medicine glass bottom, and now medicine glass is encapsulated
Cover as sunk structure, medicine glass is normally steadily placed.
Atomization module of the present invention, atomizing piece is equipped with side, is atomization module bottom on the outside of atomizing piece, for
External world's isolation, it is to avoid bacterium or noxious material pollution.It is preferred that, the atomizing piece is piezoelectric ceramic thin sheet.It is further preferred that
There are particular size, netted equally distributed microcellular structure on the piezoelectric ceramic atomizer patch.It is further preferred that the micropore
Size is less than 5 microns.
The overall structure that atomization module of the present invention can be combined into one with medicine glass, is recycled outside independently of this
The atomization plant main frame of invention is atomized to the decoction in medicine glass.Now, medicine glass module does not contain atomization mouth cap and led
Electric probe, and encapsulating film is only set.And be atomized the conducting probe on module and directly visited by the access on wire and medicine glass module
Pin is connected.Remove or destroy medicine glass atomization mouth encapsulating film using ad hoc fashion before atomization.When connecting the atomization without atomizing piece
After device Host, the atomization to decoction is directly realized by.
Above-mentioned overall structure, can also not contain encapsulating film, now between the atomizing piece and medicine glass component of atomizing component
There is membrane layer, for isolating atomizing piece and decoction.
The inseparable overall structure that above-mentioned atomizing piece module and medicine glass module are integrated, either encapsulating film still every
Film layer, must destroy or remove in a specific way before atomization, and the destruction or removing method include but is not limited to puncture, squeezed
Press, detach, so that decoction is directly contacted with atomizing piece, realize the atomization to medicine.
Above-mentioned inseparable overall structure, the case that can be held as drug solution in medicine production process.
In this overall structure, atomizing component can be located at top, the side or bottom of medicine glass component.
The present invention uses above scheme, has the following advantages that compared with prior art:
Atomization module is independent from atomization plant main frame, and the medicine glass composition corollary apparatus with containing decoction eliminates medicine
Thing be atomized after cleaning step, it is to avoid the medicine cross pollution caused by clear do not wash clean, and reduce atomization plant main frame
The loss of itself, can extend its service life.In addition, will be atomized module is atomized the medicine glass of decoction with containing as a set of independent
Device, while convenient use, accurately can also be quantified to drug dose, reduce error, improve drug effect.
Brief description of the drawings
In order to illustrate more clearly of technical scheme, the accompanying drawing used required in being described below to embodiment
It is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, general for this area
For logical technical staff, on the premise of not paying creative work, other accompanying drawings can also be obtained according to these accompanying drawings.
Accompanying drawing 1 is drug storage and the sectional view of atomising device of a kind of nebulizer administration of the embodiment of the present invention 1;
Accompanying drawing 2 is drug storage and the exploded view of atomising device of a kind of nebulizer administration of the embodiment of the present invention 1;
Accompanying drawing 3 is drug storage and the sectional view of atomising device of a kind of nebulizer administration of the embodiment of the present invention 2;
Accompanying drawing 4 is drug storage and the sectional view of atomising device of a kind of nebulizer administration of the embodiment of the present invention 3.
In above-mentioned accompanying drawing,
1st, medicine glass;11st, upper lid;110th, air-vent;111st, breather hole cover;111a, weak point;12nd, cup;120th, it is atomized mouth;
121st, inward flange;122nd, outward flange;123rd, the first conducting probe;13rd, bottom;130th, access probe;
2nd, isolated part;21st, cap;21a, weak point;22nd, encapsulating film;23rd, membrane layer
3rd, it is atomized module;30th, atomizing piece;31st, atomizing face mask seat;32nd, atomizing piece silica gel sheath;33rd, it is atomized module bottom;34th, spiral shell
Silk;35th, the second conducting probe.
Embodiment
Presently preferred embodiments of the present invention is described in detail below in conjunction with the accompanying drawings, so that advantages and features of the invention energy
It is easier to be understood by the person skilled in the art.Herein it should be noted that the explanation for these embodiments is used to help
Understand the present invention, but do not constitute limitation of the invention.In addition, involved in each embodiment of invention described below
As long as and to technical characteristic do not constitute each other conflict can just be combined with each other.
Embodiment 1
The present embodiment provides drug storage and the atomising device of a kind of nebulizer administration, by medicine glass module, atomization module and isolation
The part of part three is constituted.The drug storage of the nebulizer administration and atomising device can be set as independent device in connection atomization
After standby main frame, directly the medicine in medicine glass module can be atomized, then the atomizing face mask by connection on the apparatus
Or suction nozzle is administered to patient.Isolated part, between medicine glass module and atomization module, for permitting only in atomized medicine introducing
Perhaps decoction contact is atomized the atomization part of module;The drug storage of the nebulizer administration and atomising device have atomized medicine introducing state,
In atomized medicine introducing state, isolated part is pulled out, removes or destroyed, decoction and atomization part contact in medicine glass.
In the present embodiment, medicine glass module and atomization module are integral types, and package parts are set directly at medicine glass mould
In group.Referring to the drawings shown in 1-2, medicine glass module includes medicine glass 1, and medicine glass 1 is made up of cup 12, upper lid 11 and bottom 13, upper lid
11 and bottom 13 be respectively fixedly connected with the upper and lower ends portion of cup 12 be used for closed so that wherein formed one be used for contain
Put the cavity of decoction.Wherein, offered on the side wall of cup 12 offered on the atomization that is connected with cavity mouthful 120, upper lid 11 with
The air-vent 110 of cavity connection, and upper lid 11 and one is integrally formed or solid for the breather hole cover 111 for closing air-vent 110
Fixed connection, is specially to be made up of medical grade plastic cement.The breather hole cover 111 has weak point 111a(It is particularly located at and upper lid 11
Junction), during by external force, it is broken at weak point 111a and causes breather hole cover 111 to be broken off and expose air-vent 110.Make
Used time can pass through certain strength(Such as break, draw, pull)Breather hole cover 111 is separated with upper lid 11, be easy to the medicine of the inside
Solution is poured out or drawn.The middle part of bottom 13 is embedded with a pair of access probes 130, is for connecting the first of atomization plant main frame
A part for connection member.Atomization plant main frame herein refers to the main part for not including the atomization plant of atomization module, its
One of effect is the drug storage and atomising device offer electric signal to the nebulizer administration.When the storage of the nebulizer administration
After medicine and atomising device connection atomization plant main frame, access probe 130 obtains electric signal from atomization plant main frame and to described
Atomization module 3 is transmitted.
One or more of the isolated part 2 in cap, encapsulating film and membrane layer;Wherein, specific set-up mode
It is as follows:
Cap is connected on the wall of cup of medicine glass 1 to close atomization mouth 120, and cap is thin with what is be broken after by external force
Weak portion;
Encapsulating film can be pulled out, crimp or be arranged on puncturing medicine glass 1 and atomization module 3 between or medicine glass 1 on or be atomized
On module 3;
Membrane layer covers to be formed on atomization part and can be destroyed or remove.
In drug storage and atomising device specific to the nebulizer administration shown in accompanying drawing 1, have extremely on the outer wall of medicine glass 1
A few circle is outward extended flange, and flange is set around atomization mouth 120, and isolated part 2 is arranged on flange.More specifically, mist
Change mouth 120 to be opened on the side wall of cup 12, flange formation is on the side wall of cup 12, and isolated part 2 includes the He of cap 21
Encapsulating film 22.The flange includes inward flange 121 and outward flange 122, and inward flange 121 is set around atomization mouth 120, outward flange
122 are set around inward flange 121, and isolated part 2 includes cap 21 and encapsulating film 22, and cap 21 is arranged on inward flange 121
Upper and cap 21 has the weak point 21a being broken after by external force, and encapsulating film 22 is arranged on the outward flange 122 and can
It is punctured or crimp, both cap 21 and encapsulating film 22 cover atomization mouth 120 successively.In use, medicine glass 1 is atomized mouth
120 encapsulating film 22 and cap 21 can be separated by certain strength with medicine glass 1.
It is a component containing atomizing piece 30 to be atomized module 3.It is atomized the atomizing piece 30 in module 3, preferably piezoelectric ceramics mist
Change piece.Uniform, a diameter of micron-sized multiple micropores are distributed with atomizing piece 30, the size of micropore is less than 5 microns,
These micropore close-packed arrays, in net distribution.The atomizing piece 30 is in atomizing piece silica gel sheath 32, and atomizing piece silica gel sheath 32 is set
In in atomization module bottom 33.Atomizing piece 30 is fixed in atomizing piece silica gel sheath 32 by fixed primary screw 34.
Provided with a pair of first conducting probes 123 with the corresponding electrical connection of access probe 130 in the atomization mouth 120 of medicine glass 1,
First conducting probe 123 is telescopic.It is atomized a pair second conductive spies that module 3 includes powering to piezoelectric ceramic atomizer patch 30
Pin 35, when the atomized medicine introducing device is in atomized medicine introducing state, cap 21 and encapsulating film 22 are removed, the first conducting probe
123 and second conducting probe 35 directly connect, by the electric signal transmission of atomization plant main frame to atomizing piece 30.First conducting probe
123 be specially telescopic conducting probe, is preferably placed at the medium position of atomization mouth 120, can change position by sliding, be easy to
Connect with the second conducting probe 35 for being atomized module 3.It is further preferred that the first conducting probe 123 and the second conducting probe 35
It is parallel and arrange in the horizontal direction.Second conducting probe 35 is connect by the space at the middle part of atomizing piece silica gel sheath 32 with atomizing piece 30
Touch.Second connecting portion part includes atomizing face mask seat 31, and the opposite side of atomizing piece 30 is communicated with atomizing face mask seat 31.Access probe 130
Also it can directly be electrically connected by wire with the second conducting probe 35, and be not provided with the first conducting probe 123.
This embodiment offers medicine glass module separable and being applied in combination and the atomization form of module 3, i.e., both are in clinic
It is two independent components before atomized medicine introducing.In use, medicine glass module can form a whole with atomization module 3, connection is free of
After the atomization plant main frame of atomizing piece 30, directly the liquid medicine in medicine glass module can be realized and be atomized.
Embodiment 2
Referring to the drawings shown in 3, the basic be the same as Example 1 of the present embodiment, with differing only in for embodiment 1:
Use using mutual separable medicine glass module and the atomization form of module 3 and after combining, be not provided with medicine glass module
Decoction, is now mainly isolated from the outside, broken after cap 21 by encapsulating film by cap 21, is butted into atomization module 3
One, connects atomization plant main frame, realizes the atomization to decoction.
Embodiment 3
Referring to the drawings shown in 3, the basic be the same as Example 1 of the present embodiment, with differing only in for embodiment 1:
Medicine glass 1 and atomization module 3 are assembled into one in the mill, inseparable during medicine storage and transport, medicine glass
Module is free of cap 21, encapsulating film 22 and inward flange 121, but sets one layer on the surface of atomizing piece 30 of atomization module 3
Membrane layer 23, atomization module 3 is plugged in outward flange 122, and the first conducting probe 123 and the second conducting probe 35 directly connect.
In use, removing or destroying membrane layer 23, drug solution is directly contacted with atomizing piece 30, connect the mist without atomizing piece 30
Change after device Host, directly the liquid medicine in medicine glass module can be realized and be atomized.
In addition, mode is also implemented as follows:
Medicine glass 1 and atomization module 3 are assembled into one in the mill, inseparable during medicine storage and transport, medicine glass
Module is free of the second conducting probe 35 on the conducting probe 123 of cap 21 and first, atomization module 3 by wire directly and medicine
Access probe 130 on cup module is electrically connected, in use, by specific mode, the encapsulating film 22 on medicine glass module is removed
Or destruction, drug solution is directly contacted with atomizing piece 30, connect after the atomization plant main frame without atomizing piece 30, can be direct
Atomization is realized to the liquid medicine in medicine glass module.
Medicine glass module of the present invention and atomization module 3, both are combined with each other into the device that a kind of drug solution is atomized.
The atomization mouth 120 of medicine glass 1 removes encapsulating film 22 and the atomization cap 21 of mouth 120, and atomization module 3 removes after atomization module bottom 33,
Both are mutually butted, and the decoction in medicine glass 1 is fully contacted with atomizing piece 30.When atomizer main frame of the connection without atomizing piece 30
Afterwards, it can be driven and be atomized by various methods, including but not limited to the means such as injection, mesh or ultrasound, realize the mist to decoction
Change.It is preferred that, the medicine glass module and atomization module 3 are independent components, using preceding by being realized after slitless connection to decoction
Atomization.It is further preferred that the atomization driving force of the atomization module 3 is atomized for mesh.
The present invention provides a kind of new decoction packaged form for medicine production, i.e., by medicine sterile production process
It is middle that medicine is contained in medicine glass 1, it is isolated from the outside by encapsulating film 22, realizes Preservation in sterile condition and the transport of medicine.The present invention
By the atomizing piece 30 of the drug storage of nebulizer administration and atomising device from atomization plant it is independent, combined with medicine glass module
Into a kind of new drug solution storage and atomising device.
Medicine glass module is separable component with atomization module 3, and using preceding removal isolated part 2, both are combined into one,
After decoction is contacted with atomizing piece 30, the atomization of medicine is realized.During drug packages, it is preferred that each medicine glass module is equipped with
One atomization module 3.In addition it is also possible to be equipped with the quantity of medicine glass module and atomization module 3 according to the course for the treatment of of medicine.
Medicine glass module of the present invention can also be inseparable entirety with atomization module 3, in medicine production process
In be used for hold drug solution.Drug solution in medicine glass module and it is atomized between the atomizing piece 30 of module 3 and has encapsulating film 22
Or membrane layer, to prevent drug solution from being contacted with the direct of atomizing piece 30.In use, by specific mode, including but do not limit
In puncturing, the mode such as peel off, extract, extruding, making after drug solution directly contacts with atomizing piece 30, to carry by atomization plant main frame
The electric signal of confession, realizes the atomization to drug solution.
The above embodiments merely illustrate the technical concept and features of the present invention, is a kind of preferred embodiment, and its purpose exists
It can understand present disclosure in person skilled in the art and implement according to this, the protection of the present invention can not be limited with this
Scope.Equivalent transformation or modification that all principles according to the present invention are made, should all be included within the scope of the present invention.