CN107198738A - A kind of joint anti-inflammatory analgesic massage liquid and preparation method thereof - Google Patents

A kind of joint anti-inflammatory analgesic massage liquid and preparation method thereof Download PDF

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Publication number
CN107198738A
CN107198738A CN201710486905.8A CN201710486905A CN107198738A CN 107198738 A CN107198738 A CN 107198738A CN 201710486905 A CN201710486905 A CN 201710486905A CN 107198738 A CN107198738 A CN 107198738A
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parts
massage liquid
inflammatory analgesic
alcohol
formula ratio
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赵建军
赵志辉
赵萌
谭雯卿
赵丛勤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a kind of joint anti-inflammatory analgesic massage liquid and preparation method thereof, it is made up of the raw material of following parts by weight:30 36 parts of Radix Folium Allii tuberosi, 13 parts of safflower, 89 parts of white sugar, 46 parts of the sophora bud, 0.3 1 parts of hot pepper, 13 parts of peppermint, 12 parts of camphor, 26 parts of bagodryl hydrochloride, 79 parts of belladonna, 20 36 parts of alcohol.Massage liquid is made through extracting, boiling, mix in said medicine.The present invention mainly uses cheap Chinese herbal medicine, can family manufacture, expense is relatively low, and safety of medicine is reliable, has no side effect, and treatment bruises and sprains and arthralgia disease instant effect, short treating period, cure rate are high, reach purpose for the treatment of both principal and secondary aspect of disease.Obvious effective rate obvious effective rate 96% of the present invention, total effective rate 98%.

Description

A kind of joint anti-inflammatory analgesic massage liquid and preparation method thereof
Technical field
The present invention relates to a kind of external application massage liquid, particularly a kind of pass for causing to swell and ache by bruises and sprains, Bones and joints strain Save anti-inflammatory analgesic massage liquid and preparation method thereof.
Background technology
Osteoarthrosis pain is divided into bruises and sprains and strain causes pain, caused by severe patient is with intracavitary hydrops and other discomforts Dyskinesia, it is handicapped.The analysis of the reason for arthralgia can be summarized as three major types:One is that hand or injury of knee joint cause joint Pain, such as:1st, knee fat pad strains, and 2, meniscus injury, 3, traumatic synovitis of knee joint, 4, knee joint osseous arthritis. Two be that lumbar vertebrae, lumbar vertebrae or hip-joint disease cause gonalgia.Three be that rheumatism causes gonalgia.As medical treatment detection is set Preparation exhibition, film making is easy to inspection and makes a definite diagnosis out the affiliated type of arthralgia.Brought because cartilage layers belong to vesselless tissue to treatment Difficulty, causes such disease obstinate.The medicine for the treatment of osteoarthrosis pain is based on anti-inflammatory analgesic class Western medicine at present, Huan Zhezhi More cost is high, there is the hidden danger of recurrence.Clinical Minimally Invasive Surgery often leaves many sequelae.
The content of the invention
The technical problem to be solved in the present invention is to provide the high joint anti-inflammatory analgesic of a kind of instant effect, short treating period, cure rate Massage liquid and preparation method thereof.
In order to solve the above technical problems, the present invention is made up of the raw material of following parts by weight:30-36 parts of Radix Folium Allii tuberosi, safflower 1-3 Part, 8-9 parts of white sugar, 4-6 parts of the sophora bud, 0.3-1 parts of hot pepper, 1-3 parts of peppermint, 1-2 parts of camphor, 2-6 parts of bagodryl hydrochloride, top 7-9 parts of eggplant, 20-36 parts of alcohol.
The preparation method of the present invention, comprises the following steps:
A. the camphor of formula ratio, peppermint are ground to form fine powder and be put into vessel, pour into extraction extract after alcohol stirring and dissolving standby With;
B. the Radix Folium Allii tuberosi of formula ratio, belladonna are cut into slices, hot pepper is crushed, adds safflower, the sophora bud, boiled with conventional method slow fire More than 50 minutes, extract filtered fluid standby;
C. the bagodryl hydrochloride of formula ratio is ground to form into fine powder standby;
D. extract, filtered fluid are put into vessel, add formula ratio bagodryl hydrochloride powder, white sugar be sufficiently mixed it is molten Solution, stirs as joint anti-inflammatory analgesic massage liquid.
Described alcohol is concentration 75%-90% medicinal alcohol.
The present invention application method be:Patient's bruises and sprains or strain pain local skin are cleaned with water, by the present invention's Massage liquid is applied to affected part and slightly rubbed, then be equipped be applied to point st 36, Yongquan acupoint, point ex-le 5, Heding cave, SANYINJIAO acupoint, Kunlun point, CHENGSHAN acupoint, Weizhong point;Point Hegu, Jingqu cave, Waiguan point, yangsi (Jing-River Point,LI 5) cave, Laogongxue of hand etc. are massaged.One day 3-5 times.
The traditional Chinese medical science thinks not general rule pain, general rule not pain.The Radix Folium Allii tuberosi middle benefit gas promoting the circulation of qi of the present invention, promoting the circulation of qi of assaulting the main target, dissipates the stasis of blood;With Capsicum has the strong effect stimulated circulation, and the sensible of safflower wards off dirty, control traumatic injury;Using the sensible of camphor, only Bitterly, ward off dirty, the calmness of belladonna, anesthesia, analgesic effect;Using peppermint blood-breaking stop dysentery, easing joint movement, the sophora bud is cold, and cool blood is stopped Blood is subsided a swelling to complement each other with peppermint effect, and bagodryl hydrochloride is used for allergy, angioneurotic edema, the skin scabies of skin and mucosa Itch disease, drug rash, the mucocutaneous allergy of contact, such as nettle rash, angioneurotic edema, allergic rhinitis, cutaneous pruritus, Drug rash is also effective to insect bite disease and Contact hyper sensitization;Massage liquid containing medicinal alcohol equably massages patient's compression position, can reach To local blood circulation is promoted, the cutaneous vasodilation of patient can be made, increase the heat-sinking capability of skin, its volatility can also absorb And substantial amounts of heat is taken away, make remission;Peppermint, camphor can be dissolved in liquid rapidly by other alcohol, and alcohol is also made Increase curative effect for efficacy-enhancing ingredient, white sugar can make patient be favorably improved absorption of the body to calcium to the sensitiveness decline white sugar of pain, this Outside, white sugar has antibacterial corrosion-resistant to act on.Rationally, arthralgia can be alleviated rapidly to compatibility of the present invention by being aided with massage, cure joint Inflammation eliminates pain.
The invention has the advantages that:It is main with reference to the practical experience of inventor for many years on the basis of China's Traditional Chinese medical theory To use cheap Chinese herbal medicine, can family manufacture, expense is relatively low, and safety of medicine is reliable, has no side effect, and treatment bruise is turned round Injure arthralgia disease instant effect, short treating period, cure rate high, reach purpose for the treatment of both principal and secondary aspect of disease.Obvious effective rate 96% of the present invention, always has Efficiency 98%.
Embodiment
Embodiment 1
30 grams of Radix Folium Allii tuberosi, 1 gram of safflower, 9 grams of white sugar, 6 grams of the sophora bud, 0.3 gram of hot pepper, 1 gram of peppermint, 1.5 grams of camphor, hydrochloric acid benzene sea 6 grams of Lamine, 7 grams of belladonna, 28 milliliters of alcohol, alcohol are concentration 75%-90% medicinal alcohol.
Embodiment 2
33 grams of Radix Folium Allii tuberosi, 3 grams of safflower, 8.5 grams of white sugar, 4 grams of the sophora bud, 0.6 gram of hot pepper, 2 grams of peppermint, 2 grams of camphor, hydrochloric acid benzene sea 2 grams of Lamine, 8 grams of belladonna, 20 milliliters of alcohol, alcohol are concentration 75%-90% medicinal alcohol.
Embodiment 3
36 grams of Radix Folium Allii tuberosi, 2 grams of safflower, 8 grams of white sugar, 5 grams of the sophora bud, 1 gram of hot pepper, 3 grams of peppermint, 1 gram of camphor, bagodryl hydrochloride 4 grams, 9 grams of belladonna, 36 milliliters of alcohol, alcohol be concentration 75%-90% medicinal alcohol.
The joint anti-inflammatory analgesic massage liquid, is prepared as follows:
A. the camphor of formula ratio, peppermint are ground to form fine powder and be put into vessel, pour into extraction extract after alcohol stirring and dissolving standby With;
B. the Radix Folium Allii tuberosi of formula ratio, belladonna are cut into slices, hot pepper is crushed, adds safflower, the sophora bud, boiled with conventional method slow fire More than 50 minutes, extract filtered fluid standby;
C. the bagodryl hydrochloride of formula ratio is ground to form into fine powder standby;
D. extract, filtered fluid are put into vessel, add formula ratio bagodryl hydrochloride powder, white sugar be sufficiently mixed it is molten Solution, stirs as joint anti-inflammatory analgesic massage liquid.
Clinical curative effect analysis
1. case selection:Selection arthralgia patient 80, minimum eight years old 1 people, -21 years old 12 years old 12 people, are traumatic injury;Its Remaining is more than 56 years old 67 people, and course of disease first quarter moon, by 1 year, is mostly meniscus injury, traumatic synovitis of knee joint, knee joint bone Arthritis, scapulohumeral periarthritis, severe patient is with intracavitary hydrops, oedema.
2. treatment method:Patient's bruises and sprains or strain pain local skin are cleaned with water, the massage liquid of the present invention is applied It is put on affected part slightly to rub, then is equipped with and is applied to point st 36, Yongquan acupoint, point ex-le 5, Heding cave, SANYINJIAO acupoint, Kunlun point, holds Mountain cave, Weizhong point;Point Hegu, Jingqu cave, Waiguan point, yangsi (Jing-River Point,LI 5) cave, Laogongxue of hand etc. are massaged.3-5 times on the one, three Month course for the treatment of.
3. curative effect judging standard
It is effective:Pain substantially mitigates two days later for medication, sprains patient and sprains within one month healing;Arthralgia is suffered from intracavitary ponding Two courses for the treatment of of person can just walk freely.
Effectively:One course for the treatment of arthralgia of meniscus injury medication is alleviated, and three course for the treatment of ponding are disappeared, and arthralgia is controlled More.
It is invalid:Three days pain of medication can not be alleviated, still handicapped after a course for the treatment of.
4. therapeutic effect:In 80 patients, 13 people of traumatic injury fully recovers for one month;Meniscus injury, other Bones and joints pain The people of pain patient 64, two courses for the treatment of are cured, and another 2 people is pain relief, now still handicapped, with oedema, 1 people's medication three days pain Pain can not be alleviated, still handicapped after a course for the treatment of.Obvious effective rate 96%, total effective rate 98%.
5. model case
Lu XX, female, 68 years old, retired professor rode a bicycle before 5 years and fallen, injures meniscus, be chondromalacia patella through examination in hospital, Meniscus secondary damage, intracavitary inflammation have ponding, hospital's suggestion Minimally Invasive Surgery.Patient's refusal operation, using the massage of the present invention Liquid massages two course for the treatment of walkings freely, and hydrops disappears in three course for the treatment of knee joint cavities.Morning exercises is participated on Neng Dao squares, so far without multiple Hair.
X U.S.s tinkling of pieces of jade, female, 60 years old, retired worker, jumping square dance causes the damage of meniscus relief angle, side seam in left tibias platform A small amount of hydrops in damage, left Knee injuries, left knee articular cavity, smears knee using joint anti-inflammatory analgetic massage liquid and closes Section, two courses for the treatment of can take care of oneself.
Xx, female, 63 years old, due to overworking, two leg knee oedema, it is impossible to walk, under not building, using the present invention's Massage liquid massage therapy, has stopped pain, oneself can walk, hydrops has alleviation in articular cavity, further in treatment.

Claims (3)

1. a kind of joint anti-inflammatory analgesic massage liquid, it is characterized in that being made up of the raw material of following parts by weight:It is 30-36 parts of Radix Folium Allii tuberosi, red 1-3 parts of flower, 8-9 parts of white sugar, 4-6 parts of the sophora bud, 0.3-1 parts of hot pepper, 1-3 parts of peppermint, 1-2 parts of camphor, bagodryl hydrochloride 2-6 Part, 7-9 parts of belladonna, 20-36 parts of alcohol.
2. the preparation method of anti-inflammatory analgesic massage liquid in joint according to claim 1, it is characterized in that comprising the following steps:
A. the camphor of formula ratio, peppermint are ground to form fine powder and be put into vessel, pour into extraction extract after alcohol stirring and dissolving standby With;
B. the Radix Folium Allii tuberosi of formula ratio, belladonna are cut into slices, hot pepper is crushed, adds safflower, the sophora bud, boiled with conventional method slow fire More than 50 minutes, extract filtered fluid standby;
C. the bagodryl hydrochloride of formula ratio is ground to form into fine powder standby;
D. extract, filtered fluid are put into vessel, add formula ratio bagodryl hydrochloride powder, white sugar be sufficiently mixed it is molten Solution, stirs as joint anti-inflammatory analgesic massage liquid.
3. the preparation method of anti-inflammatory analgesic massage liquid in joint according to claim 2, it is characterized in that described alcohol is dense Spend 75%-90% medicinal alcohol.
CN201710486905.8A 2017-06-23 2017-06-23 A kind of joint anti-inflammatory analgesic massage liquid and preparation method thereof Withdrawn CN107198738A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057541A (en) * 2020-10-09 2020-12-11 湖南科技学院 Pain-relieving inflammation-diminishing gel and preparation method and application thereof

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CN104013729A (en) * 2014-06-20 2014-09-03 安徽安科余良卿药业有限公司 Arthralgia relieving gel and preparation method thereof
CN105521237A (en) * 2014-09-29 2016-04-27 吕奎荣 Externally applied medicine for treating traumatic injuries

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013729A (en) * 2014-06-20 2014-09-03 安徽安科余良卿药业有限公司 Arthralgia relieving gel and preparation method thereof
CN105521237A (en) * 2014-09-29 2016-04-27 吕奎荣 Externally applied medicine for treating traumatic injuries

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057541A (en) * 2020-10-09 2020-12-11 湖南科技学院 Pain-relieving inflammation-diminishing gel and preparation method and application thereof

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