CN105012594A - Traditional Chinese medicine for treating knee osteoarthritis - Google Patents

Abstract

A traditional Chinese medicine for treating knee osteoarthritis is prepared from creeping psychotria, gendarussa ventricosa, ceropegia trichantha, entada phaseoloides, angelica dahurica, rhaphidophora peepla, embelia parviflora, taxillus sutchuenensis, ground beetles and david's deer horn. The traditional Chinese medicine provided by the invention can be clinically used for treating knee osteoarthritis.

Description

A kind of Chinese medicine for the treatment of knee osteoarthritis

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of knee osteoarthritis.

Background technology

Knee joint osseous arthritis is, synovial membrane inflammation hypertrophy narrow with knee cartilage degeneration, joint space and joint margins hyperosteogeny is main pathological change, with the gonalgia, swelling, impact is squatted down and daily life is main manifestations common disease.At present, doctor trained in Western medicine there is no effective especially Therapeutic Method to this disease, although application NSAI drugs can alleviating pain, but can not the cause of disease be dispelled, cannot delay or reverse the regression of articular cartilage, and easily recur after drug withdrawal and cause digestive system and hepatic and renal function injure, therefore, Chinese medicine increases gradually in the research in this field, and achieves good result.

Summary of the invention

The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment knee osteoarthritis of human non-toxic's side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt wear rattan root, Ramulus Et Folium Adhatodae Ventricosea, Herba Ceropegiae Christensenianae, turn round GUFENG, the Radix Angelicae Dahuricae, large Ye Nansu, Radix seu Caulis Embeliae Parviflorae, Herba Taxilli, Eupolyphaga Seu Steleophaga, Cornu Elaphuri davidiani, according to certain compatibility requirement, through being processed into.

Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: wear rattan root 30-40 part, Ramulus Et Folium Adhatodae Ventricosea 20-30 part, Herba Ceropegiae Christensenianae 20-30 part, turn round GUFENG 15-25 part, Radix Angelicae Dahuricae 15-25 part, great Ye south Soviet Union 15-25 part, Radix seu Caulis Embeliae Parviflorae 15-25 part, Herba Taxilli 15-25 part, Eupolyphaga Seu Steleophaga 8-12 part, Cornu Elaphuri davidiani 5-10 part.

Optimum weight part of raw material of Chinese medicine medicine of the present invention is: wear rattan root 35 parts, Ramulus Et Folium Adhatodae Ventricosea 25 parts, Herba Ceropegiae Christensenianae 25 parts, turn round GUFENG 20 parts, the Radix Angelicae Dahuricae 20 parts, great Ye south Soviet Union 20 parts, Radix seu Caulis Embeliae Parviflorae 20 parts, Herba Taxilli 20 parts, Eupolyphaga Seu Steleophaga 10 parts, Cornu Elaphuri davidiani 6 parts.

The pharmacological action of Chinese medicine of the present invention is as follows:

Ramulus et Folium Psychotriae Serpentis: bitter, pungent, flat.Return liver, heart channel.Wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain.Clinical in rheumatic arthritis, numb hand and foot, psoas muscle labor fingerprint, sciatica, multiple carbuncle, bone tuberculosis, traumatic injury, fracture, the diseases such as venom.

Ramulus Et Folium Adhatodae Ventricosea: pungent, bitter, flat.Promoting blood circulation and stopping pain, blood stasis dispelling synthetism, expelling wind and removing dampness, subduing swelling and detoxicating.Clinical in traumatic injury, fracture, impairment caused by overstrain lumbago, rheumatic arthralgia, peratodynia, lung abscess, acute mastitis, innominate toxic swelling, wound redness waits disease.

Herba Ceropegiae Christensenianae: sour, flat.Heat-clearing and toxic substances removing.Clinical in the disease such as innominate toxic swelling, fracture.

Turn round GUFENG: bitter, puckery, flat.Return kidney channel.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Clinical in rheumatic arthralgia, traumatic injury, lumbar muscle strain, the diseases such as numb limbs and tense tendons.

The Radix Angelicae Dahuricae: pungent, warm.Return lung, spleen, stomach warp.Expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis.Clinical in headache of catching a cold, supraorbital bone pain, toothache, nasal obstruction, nasal sinusitis, wet Sheng chronic diarrhea, women leucorrhea, ulcer sores, the diseases such as venom.

Large Ye Nansu: bitter, micro-sweet, cool.Eliminating stasis to stop pain, relaxing muscles and tendons and activating QI and blood in the collateral, nourishing the lung to arrest cough.Clinical in angina pectoris, traumatic injury, fracture, rheumatic arthralgia, numb limbs and tense tendons, bronchitis, the diseases such as pertussis.

Radix seu Caulis Embeliae Parviflorae: bitter, puckery, warm.Return liver, kidney channel.Enrich blood, invigorate blood circulation, strong waist knee joint.For all diseases of blood deficiency, menoxenia, amenorrhea, puerperal asthenia, waist and leg ache, the diseases such as injury and bone fracture.

Herba Taxilli: bitter, sweet, flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive.For soreness of waist and knee joint, muscles and bones is thin and weak, rheumatic arthralgia, frequent fetal movement, metrostaxis.

Eupolyphaga Seu Steleophaga: salty, cold.Return Liver Channel.Removing blood stasis, reunion of fractured tendons and bones.Clinically amass block for blood stasis amenorrhea ， mass in the abdomen; Traumatic injury congestive edema, the diseases such as muscles and bones fracture.

Cornu Elaphuri davidiani: sweet, warm.Return kidney channel.Warming the kidney to invigorate YANG, adds essence and mends marrow, bone and muscle strengthening, beneficial blood vessels.For insufficiency of kidney-YANG, asthenia damage of essence, soreness of the waist and knees, bones and muscles pain, Blood deficiency etc.

Knee osteoarthritis belongs to the category of Chinese medicine " rheumatism involving the bone ", " lumbago and skelalgia "." Plain Questions declares five gas " section is said: " impairment of blood by looking for a long time, excessive rest on bed impairing QI ... "Describing long-term chronic strain is the one of the main reasons causing osteoarthritis.In the present invention, Ramulus et Folium Psychotriae Serpentis is monarch drug, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain; Ramulus Et Folium Adhatodae Ventricosea promoting blood circulation and stopping pain, blood stasis dispelling synthetism, expelling wind and removing dampness, subduing swelling and detoxicating, Herba Ceropegiae Christensenianae heat-clearing and toxic substances removing is ministerial drug; Turn round GUFENG expelling wind and removing dampness, promoting blood circulation and stopping pain, Radix Angelicae Dahuricae expelling wind and removing dampness, understand things pain-stopping, large Ye Nansu eliminating stasis to stop pain, relaxing muscles and tendons and activating QI and blood in the collateral, Radix seu Caulis Embeliae Parviflorae is invigorated blood circulation, strong waist knee joint, Herba Taxilli invigorating the liver and kidney, bone and muscle strengthening, Eupolyphaga Seu Steleophaga reunion of fractured tendons and bones, Cornu Elaphuri davidiani bone and muscle strengthening, beneficial blood vessels.Find through clinical practice, have unique curative effect to knee osteoarthritis, all medicines play relaxing muscles and tendons and activating QI and blood in the collateral altogether, reducing swelling and alleviating pain, effect of blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, strong muscles and bones, reach the object for the treatment of knee osteoarthritis.

Chinese medicine of the present invention was in 2010 to 2014 the routine patients of clinical observation knee osteoarthritis 59, and clinical report is as follows:

1, physical data

In 59 routine patients, in age 38-71 year, the course of disease is many at 3 months to 6 years, 61 years old mean age.

2, diagnostic criteria

Draft with reference to " arthritis diagnosis and treatment draft guidelines gonarthritis in 2002 diagnostic criteria of rheumatism branch of Chinese Medical Association ":

1. nearly one month frequent gonalgia repeatedly; 2. X-ray film (erect position or Weight carrying position) joint space narrows; 3. limpid, the thickness of joint fluid (at least 2 times), WBC≤200/ml; 4. person in middle and old age person (>=40 years old); 5. knee joint deadlock in morning≤30 minutes; 6. friction sound is had during activity.Meet and 1. 2. or 3. 5. 6. or 1. 4. 5. 6. namely form diagnosis.According to sign: the 1. gonalgia, walking function obstacle, exacerbation of symptoms when fatigue and stair activity, involves periarticular muscles pain.2. health check-up knee joint is unrestrained swollen, patella and inside and outside Xiyan place tenderness+, patella grinding pain, floating patella test+, it is limited that knee joint stretches flex, atrophy of quadriceps femoris.

3, Therapeutic Method

3.1 prescriptions: wear rattan root 35g, Ramulus Et Folium Adhatodae Ventricosea 25g, Herba Ceropegiae Christensenianae 25g, turn round GUFENG 20g, 20g, Radix seu Caulis Embeliae Parviflorae 20g, Herba Taxilli 20g, Eupolyphaga Seu Steleophaga 10g, Cornu Elaphuri davidiani 6g are revived in the Radix Angelicae Dahuricae 20g, great Ye south.

3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 20 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 treatment evaluation criterias, judge according to " the Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine formulates:

Clinical cure: knee joint swelling, pain disappear, flexion-extension motion scope recovers normal, and walking is freely;

Effective: knee joint swelling substantially disappears or obviously goes down, and pain obviously alleviates, flexion-extension motion scope is normal;

Take a turn for the better: knee joint swelling and pain all have and alleviates in various degree and alleviate, and flexion-extension motion scope is also improved;

Invalid: knee joint swelling and pain are all without alleviation.

4.2 results: in 59 routine patients, clinical cure 38 example (64.4%), effective 12 examples (20.3%), 8 examples that take a turn for the better (13.6%), invalid 1 example (1.7%), total effective rate is 98.3%.

Model case

1, clump, man, 69 years old, nearly 2 years of two gonalgia, recent right swelling and pain in knee obviously increased the weight of, and above all needs staircase downstairs, seat dysstasia, and meet overcast and rainy symptom obviously, morning is stiff, occasionally has interlocking phenomenon.Check: inner side tenderness under kneecap: left knee joint (+), right knee joint (++); Right knee joint is micro-swollen, right Range of motion of knee joint: 45 °; Tongue is greasy in vain, stringy and rolling pulse.Diagnosis: knee osteoarthritis.Take medicine of the present invention, treat 2 courses for the treatment of, two swelling and pain in knee obviously alleviate, and all the other symptoms also in alleviation trend, continue to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

2, grandson, female, 62 years old, existing 3 years of two knee joint sorenesses, had Knee Trauma history and history of catching cold.Though through treatments such as Chinese medicine and western medicine pain relievings, two knee joint sorenesses still time stop when doing, recently, knee joint soreness increases the weight of, and stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: knee joint is that bone is loose, and joint space narrows.Check: tenderness (+) around two knee joints, mild swelling and limping, two knee articulation degree are limited to 45 °, have interlocking to levy, McMurray's test (+), lateroflexion (±), floating kneecap (±).Diagnosis: knee osteoarthritis.Take medicine of the present invention, every day 1 dose, after 3 courses for the treatment of, rear two knee joints are ached and are alleviated, and swelling disappears, and all the other symptoms alleviate.Continue to take 4 courses for the treatment of, recovery from illness, follow up a case by regular visits to after 1 year without recurrence.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.

Embodiment 1, a kind of Chinese medicine for the treatment of knee osteoarthritis, is by wearing rattan root 30g, Ramulus Et Folium Adhatodae Ventricosea 20g, Herba Ceropegiae Christensenianae 20g, turns round GUFENG 15g, the Radix Angelicae Dahuricae 15g, great Ye south Soviet Union 15g, Radix seu Caulis Embeliae Parviflorae 15g, Herba Taxilli 15g, Eupolyphaga Seu Steleophaga 8g, Cornu Elaphuri davidiani 5g make.

Embodiment 2, a kind of Chinese medicine for the treatment of knee osteoarthritis, is by wearing rattan root 35g, Ramulus Et Folium Adhatodae Ventricosea 25g, Herba Ceropegiae Christensenianae 25g, turns round GUFENG 20g, the Radix Angelicae Dahuricae 20g, great Ye south Soviet Union 20g, Radix seu Caulis Embeliae Parviflorae 20g, Herba Taxilli 20g, Eupolyphaga Seu Steleophaga 10g, Cornu Elaphuri davidiani 6g make.

Embodiment 3, a kind of Chinese medicine for the treatment of knee osteoarthritis, is by wearing rattan root 40g, Ramulus Et Folium Adhatodae Ventricosea 30g, Herba Ceropegiae Christensenianae 30g, turns round GUFENG 25g, the Radix Angelicae Dahuricae 25g, great Ye south Soviet Union 25g, Radix seu Caulis Embeliae Parviflorae 25g, Herba Taxilli 25g, Eupolyphaga Seu Steleophaga 12g, Cornu Elaphuri davidiani 10g make.

Claims (2)

1. treat a Chinese medicine for knee osteoarthritis, it is characterized in that it is made up of following raw material medicaments:

Wear rattan root 30-40 part, Ramulus Et Folium Adhatodae Ventricosea 20-30 part, Herba Ceropegiae Christensenianae 20-30 part, turn round GUFENG 15-25 part,

Radix Angelicae Dahuricae 15-25 part, great Ye south Soviet Union 15-25 part, Radix seu Caulis Embeliae Parviflorae 15-25 part, Herba Taxilli 15-25 part,

Eupolyphaga Seu Steleophaga 8-12 part, Cornu Elaphuri davidiani 5-10 part.

2. Chinese medicine according to claim 1, is characterized in that it is made up of following raw material medicaments:

Wear rattan root 35 parts, Ramulus Et Folium Adhatodae Ventricosea 25 parts, Herba Ceropegiae Christensenianae 25 parts, turn round GUFENG 20 parts,

The Radix Angelicae Dahuricae 20 parts, great Ye south Soviet Union 20 parts, Radix seu Caulis Embeliae Parviflorae 20 parts, Herba Taxilli 20 parts,

Eupolyphaga Seu Steleophaga 10 parts, Cornu Elaphuri davidiani 6 parts.