CN107184194A - Based on numerically controlled blood pressure self-operated measuring unit and method - Google Patents

Based on numerically controlled blood pressure self-operated measuring unit and method Download PDF

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CN107184194A
CN107184194A CN201710546747.0A CN201710546747A CN107184194A CN 107184194 A CN107184194 A CN 107184194A CN 201710546747 A CN201710546747 A CN 201710546747A CN 107184194 A CN107184194 A CN 107184194A
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blood pressure
unit
signal
pressure
measurement
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CN107184194B (en
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李晓风
许金林
谭海波
李皙茹
吕波
程龙乐
元沐南
潘婉苏
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Hefei Institutes of Physical Science of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/022Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/0225Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis

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Abstract

The present invention relates to blood pressure detecting technical field, it is related to a kind of based on numerically controlled blood pressure self-operated measuring unit and method.The measurement apparatus includes:Volume pulsation wave acquisition module, it is used for the volume pulsation wave for gathering measurement object, and the volume pulsation wave gathered is handled to obtain photoplethysmographic;Blood pressure acquisition module, it is used for the blood pressure information of timing acquiring measurement object, and the blood pressure information gathered is handled to obtain blood pressure data signal;And processing module, it includes first processing units and second processing unit, first processing units are used to be sent to second processing unit to blood pressure digital signal reception and after handling, and second processing unit is used for the multiple characteristic points for extracting photoplethysmographic and is fitted calculation process jointly to set up blood pressure parameter measurement model by the plurality of characteristic point and blood pressure data signal.The measuring method is realized by above-mentioned measurement apparatus.The present invention preferably realizes automatic, the continuous measurement to blood pressure.

Description

Based on numerically controlled blood pressure self-operated measuring unit and method
Technical field
The present invention relates to blood pressure detecting technical field, specifically, it is related to one kind and is surveyed automatically based on numerically controlled blood pressure Measure device and method.
Background technology
It is exactly the blood generally said by the pressure that heartbeat, which promotes blood circulation, causes blood to form vascular wall Pressure, blood pressure is the important physiological parameter for reflecting human recycle system's function.The automatic continuous measurement of blood pressure medically has great Practical significance, such as on clinical medicine to urgent patient and operation in patient with severe symptoms be required for carry out blood pressure continuous prison Control, once so that unexpected medical personnel, which occurs, in patient can take effective rescue measure in time.
Existing main utilization sphygmomanometer or pulse wave translation time measure blood pressure, but two kinds of blood pressure measurement modes are present Certain weak point.For the mode taken blood pressure using blood pressure measuring, measured blood pressure parameter is because of vessel wall elasticity Deng factors influence, it is impossible to reach the purpose continuously measured.For the mode using pulse wave translation time measurement blood pressure Speech, it is existing that same individual different parts are carried out typically by two pulse wave sensors to measure simultaneously, recognize two-way ripple Just as the time difference of a characteristic point, pulse wave translation time is obtained, so as to set up the blood pressure measurement based on pulse wave translation time Model, but the measurement model and its easily by external interference, and measurement model can fail and then model when measuring for a long time Coefficient need to be fitted again, therefore be not suitable for continuously and automatically blood pressure measurement yet.
The content of the invention
Numerically controlled blood pressure self-operated measuring unit is based on the invention provides one kind, it can preferably realize blood pressure Automatically, continuous measurement.
According to the present invention based on numerically controlled blood pressure self-operated measuring unit, it includes:
Volume pulsation wave acquisition module, it is used for the volume pulsation wave for gathering measurement object, and the volume arteries and veins to being gathered Ripple of fighting is handled to obtain photoplethysmographic;
Blood pressure acquisition module, it is used for the blood pressure information of timing acquiring measurement object, and the blood pressure information gathered is entered Row handles to obtain blood pressure data signal;And
Processing module, it includes first processing units and second processing unit, and second processing unit is used to extract photoelectricity Multiple characteristic points of volume pulsation wave simultaneously set up blood pressure parameter measurement model, and first processing units are used to connect blood pressure data signal Receive and be sent to second processing unit after handling to be timed correction to blood pressure parameter measurement model.
In the present invention, the volume pulsation wave of measurement object can be sampled by volume pulsation wave acquisition module, be located Reason, so as to obtain the photoplethysmographic of digital signal form and be sent to second processing unit;Second processing unit afterwards Multiple characteristic points of photoplethysmographic can be extracted and calculating is fitted to the plurality of characteristic point, so as to set up blood pressure Parameter measurement model.That is, in the present invention, finished once blood pressure parameter measurement model is set up, you can preferably according to adopting The volume pulsation wave collected obtains the blood pressure of acquisition target, so as to preferably realize the automatic measurement of blood pressure.
In the present invention, second processing unit can be divided photoplethysmographic signal using existing threshold method Analysis, so as to extract multiple characteristic points such as main ripple, tidal wave, dicrotic pulse crest, dicrotic pulse trough and trough.
In the present invention, second processing unit can be fitted meter according to langbobier law to the multiple characteristic point Calculate, the method for the Fitting Calculation is existing method, is specially:By the multiple characteristic point and pulse wave rising stage (systole phase) and Pulse wave declines the blood flow variable quantity progress simultaneous that phase (diastole) and graphics area are represented, so as to set up blood pressure parameter measurement Model.
In addition, be also particular, it is important that the blood pressure acquisition module of the present invention be capable of timing promoting circulation of blood is entered to measurement object Pressure measurement, and the data returned at blood pressure acquisition module can be parsed by first processing units, so as to timing Obtain the blood pressure parameter (such as mean pressure, systolic pressure and diastolic pressure) of measurement object and be sent to second processing unit;Afterwards The blood pressure parameter uploaded at first processing units can be fitted by two processing units with above-mentioned multiple characteristic points automatically, from And preferably realize the correction to blood pressure parameter measurement model;Designed by this kind, can preferably ensure that blood pressure parameter is surveyed The real-time accuracy of model is measured, so as to preferably realize automatic, the continuous measurement to blood pressure.
In the present invention, the correlation models of volume pulsation wave characteristic point and blood pressure parameter are set up by second processing unit (blood pressure parameter measurement model) calculates blood pressure parameter, and using blood pressure acquisition module timing acquiring standard blood parameter to the correlation Property model timing be corrected, so as to preferably realize the correction of the blood pressure parameter to being gathered by volume pulsation wave, So as to which the measurement accuracy of blood pressure self-operated measuring unit in the present invention is improved greatly.The blood pressure automatic measurement dress of the present invention Put and preferably overcome the problem of existing sphygmomanometer metering system can not continuously measure and measure not quick enough, and, it is existing to utilize The problem of pulse wave translation time metering system is not accurate enough, be provided simultaneously with equipment simple, human blood glucose, it is easy to operate, into The advantages of this is relatively low.
Preferably, being provided with the display for the memory cell of data storage and for data output at second processing unit Unit.The setting of memory cell can be stored preferably to the data obtained, and display unit can be preferably at second Data at reason unit are shown, and can pass through wireless (such as bluetooth, wi-fi) between display unit and second processing unit Communication.
Adjusted preferably, blood pressure acquisition module includes pressure generating unit, pressure unit, pressure sensor, the first signal Unit and the first A/D converting units are managed, pressure generating unit is used to provide pressure source to pressure unit, and pressure unit is used for survey The measurement point for measuring object applies pressure, and pressure sensor is used for the blood pressure information for gathering measurement object, the first signal condition list The signal that member is used to gather pressure sensor is amplified, filtered, and the first A/D converting units are used to adjust through the first signal Signal after reason cell processing is converted into data signal and is sent to processing module.So as to preferably realize to acquisition target Blood pressure measurement.
Preferably, pressure generating unit includes air pump, pressure unit includes sphygmomanometer sleeve bag, and air pump is used for sphygmomanometer It is pumped into sleeve bag and one is additionally provided with gas, sphygmomanometer sleeve bag is used for the magnetic valve that gas is discharged, air pump and magnetic valve is by one the One driver element is driven, and the control signal of the first driver element is produced by first processing units.So as to preferably realize to blood The automatic inflating of pressure meter sleeve bag and exhaust, and then be conducive to the realization of blood pressure information automatic data collection.
Preferably, being provided with a splitter at sphygmomanometer sleeve bag, splitter includes splitter cavity and connected with branch cavity Logical 1 splitter air inlet pipe, 3 splitter escape pipes, the gas outlet access tributary device air inlet pipe of air pump, 3 branches Device escape pipe is respectively used to set magnetic valve, sets pressure sensor and access sphygmomanometer sleeve bag.So as to preferably realize pair The blood pressure measurement of acquisition target.
Preferably, volume pulsation wave acquisition module turns including pulse transducer, secondary signal conditioning unit and the 2nd A/D Block is changed the mold, pulse transducer is used to gather the volume pulsation wave of measurement object and is converted into electric signal, secondary signal conditioning unit Electric signal after for being changed to pulse transducer is amplified, filtered, and the 2nd A/D modular converters are used to adjust through secondary signal Analog signal after reason cell processing is converted into the photoplethysmographic of digital signal form.Adopted so as to preferably obtain Collect the photoplethysmographic of object.
Preferably, pulse transducer includes illuminating module and light receiving unit, illuminating module is used for measurement object Measurement point emission measurement light beam, light receiving unit be used for receive measuring beam at measurement object the optical signal of reflected light and turn It is changed to electric signal;Illuminating module includes red emission pipe and near infrared emission pipe, and red emission pipe and near infrared emission pipe are used for Distinguish emission measurement light beam successively under the driving of one second driver element, the second driver element control signal is by second processing list Member is produced;Light receiving unit includes photoelectric receiving tube, and photoelectric receiving tube is used for the anti-of red emission pipe and near infrared emission pipe Penetrate optical signal and be converted to and secondary signal conditioning unit is sent to after electric signal.Red emission pipe, near infrared emission pipe and photoelectricity connect Closed tube together constitutes reflective pulse transducer, and pulse transducer can be obtained by the measure to reflected light light intensity The waveform of volume pulsation wave is taken, second processing unit is sent to by the processing of secondary signal conditioning unit afterwards, so that preferably Ground realizes the collection and processing to volume pulsation wave.
In addition, the present invention provides one kind based on any one above-mentioned blood pressure self-operated measuring unit is based on numerically controlled blood Method for automatic measurement is pressed, so as to preferably realize automatic, the continuous measurement to blood pressure.
According to the present invention based on numerically controlled blood pressure method for automatic measurement, it comprises the following steps:
(1) volume pulsation wave at measurement object arteria brachialis is gathered by volume pulsation wave acquisition module and is converted into numeral The photoplethysmographic of signal form;
(2) multiple characteristic points of photoplethysmographic are extracted using second processing unit, and to the plurality of characteristic point Calculation process is fitted, and then sets up out blood pressure parameter measurement model;
(3) use the blood pressure information of blood pressure acquisition module timing acquiring measurement object and be converted into data signal, Zhi Houtong The data signal that first processing units export blood pressure acquisition module is crossed to be handled to obtain mean pressure, systolic pressure and diastole Pressure;
(4) data sent by second processing unit according to first processing units are carried out to going out blood pressure parameter measurement model Fitting correction.
By method provided by the present invention, preferably the blood pressure of acquisition target can be carried out continuously, compared with high precision Ground is measured.
Preferably, in step (2), computing is fitted to the multiple characteristic point according to Beer-Lambert Law.Due to It is a more ripe prior art that computing is fitted to the multiple characteristic point by Beer-Lambert Law, consequently facilitating The foundation of blood pressure parameter measurement model.
Preferably, being stored using a memory cell to the data at second processing unit, using a display unit The data that second processing unit is exported are shown.So as to preferably realize the storage and output to data.
Brief description of the drawings
Fig. 1 be embodiment 1 in blood pressure self-operated measuring unit schematic diagram;
Fig. 2 be embodiment 1 in blood pressure self-operated measuring unit system block diagram;
Fig. 3 be embodiment 1 in blood pressure acquisition module circuit block diagram;
Fig. 4 be embodiment 1 in volume pulsation wave acquisition module circuit block diagram;
Fig. 5 be embodiment 1 in blood pressure method for automatic measurement flow chart.
Embodiment
To further appreciate that present disclosure, the present invention is described in detail in conjunction with the accompanying drawings and embodiments.It should be understood that , embodiment be only the present invention is explained and and it is non-limiting.
Embodiment 1
As shown in figure 1, present embodiments providing a kind of based on numerically controlled blood pressure self-operated measuring unit.It includes:Hold Product pulse wave acquisition module 110, it is used for the volume pulsation wave for gathering measurement object, and the volume pulsation wave gathered is carried out Handle to obtain photoplethysmographic;Blood pressure acquisition module 120, it is used for the blood pressure information of timing acquiring measurement object, and The blood pressure information gathered is handled to obtain blood pressure data signal;And processing module, it includes first processing units With second processing unit, second processing unit is used to extract multiple characteristic points of photoplethysmographic and sets up blood pressure parameter Measurement model, first processing units are used to be sent to second processing unit to blood pressure digital signal reception and after handling so as to blood Pressure parameter measurement model is timed correction.
In the present embodiment, the volume pulsation wave of measurement object can be adopted by volume pulsation wave acquisition module 110 Sample, processing, so as to obtain the photoplethysmographic of digital signal form and be sent to second processing unit;Second processing afterwards Unit can extract multiple characteristic points of photoplethysmographic and be fitted calculating to the plurality of characteristic point, so as to set up Blood pressure parameter measurement model.That is, in the present embodiment, being finished once blood pressure parameter measurement model is set up, you can preferably The blood pressure of acquisition target is obtained according to the volume pulsation wave collected, so as to preferably realize the automatic measurement of blood pressure.
In the present embodiment, second processing unit is analyzed photoplethysmographic signal using existing threshold method, So as to extract multiple characteristic points such as main ripple, tidal wave, dicrotic pulse crest, dicrotic pulse trough and trough.
In the present embodiment, second processing unit is fitted calculating according to langbobier law to the multiple characteristic point, The method of the Fitting Calculation is existing method, is specially:By the multiple characteristic point and pulse wave rising stage (systole phase) and arteries and veins Ripple of fighting declines the blood flow variable quantity progress simultaneous that phase (diastole) and graphics area are represented, so as to set up blood pressure parameter measurement mould Type.
In addition, be also particular, it is important that blood pressure acquisition module 120 be capable of timing to measurement object carry out blood pressure survey Amount, and the data returned at blood pressure acquisition module 120 can be parsed by first processing units, so as to regularly obtain Take the blood pressure parameter (such as mean pressure, systolic pressure and diastolic pressure) of measurement object and be sent to second processing unit;Afterwards second The blood pressure parameter uploaded at first processing units can be fitted by processing unit with above-mentioned multiple characteristic points automatically, so that Preferably realize the correction to blood pressure parameter measurement model;Designed by this kind, can preferably ensure that blood pressure parameter is measured The real-time accuracy of model, so as to preferably realize automatic, the continuous measurement to blood pressure.
In addition, in the present embodiment, first processing units and second processing unit use MCU to realize and each other can be with Wireless mode carries out data interaction.Certainly, first processing units and second processing unit can also be handed over by data/address bus Mutually.
In the present embodiment, the correlation models of volume pulsation wave characteristic point and blood pressure parameter are set up by second processing unit (blood pressure parameter measurement model) calculates blood pressure parameter, and using the timing acquiring standard blood parameter of blood pressure acquisition module 120 to this Correlation models timing is corrected, so as to preferably realize the school of the blood pressure parameter to being gathered by volume pulsation wave Just, so that the measurement accuracy of blood pressure self-operated measuring unit in the present embodiment is improved greatly.The blood pressure of the present embodiment is certainly Dynamic measurement apparatus preferably overcomes the problem of existing sphygmomanometer metering system can not continuously measure and measure not quick enough, and, The problem of existing utilization pulse wave translation time metering system is not accurate enough, is provided simultaneously with simple equipment, human blood glucose, operation It is easy, the advantages of cost is relatively low.
In addition, in the present embodiment, being additionally provided with second processing unit for the memory cell of data storage and for data The display unit of output.The setting of memory cell can be stored preferably to the data obtained, and display unit can be preferable Ground is shown to the data at second processing unit, and can pass through wireless (this reality between display unit and second processing unit Apply and bluetooth used in example) communication.
With reference to shown in Fig. 2, blood pressure acquisition module 120 includes pressure generating unit, pressure unit, pressure sensor, first Signal condition unit and the first A/D converting units, pressure generating unit are used to provide pressure source to pressure unit, and pressure unit is used In applying pressure to the measurement point of measurement object, pressure sensor is used for the blood pressure information for gathering measurement object, the first signal The signal that conditioning unit is used to gather pressure sensor is amplified, filtered, and the first A/D converting units are used for will be through first Signal after signal condition unit processing is converted into data signal and is sent to processing module.
With reference to shown in Fig. 3, pressure generating unit includes air pump, and pressure unit includes sphygmomanometer sleeve bag, and air pump is used for blood Be pumped into pressure meter sleeve bag and one is additionally provided with gas, sphygmomanometer sleeve bag is used for the magnetic valve that gas is discharged, air pump and magnetic valve by One first driver element is driven, and the control signal of the first driver element is produced by first processing units.In addition, at sphygmomanometer sleeve bag Provided with a splitter, splitter includes splitter cavity and the 1 splitter air inlet pipe connected with branch cavity, 3 splitters Escape pipe, the gas outlet access tributary device air inlet pipe of air pump, 3 splitter escape pipes are respectively used to set magnetic valve, set Put pressure sensor and access sphygmomanometer sleeve bag.
In the present embodiment, because pressure unit includes sphygmomanometer sleeve bag, so as to preferably be located at measurement object.
In the present embodiment, the first driver element includes being used for the drive circuit of driving air pump and magnetic valve respectively, and this causes First processing units can be controlled automatically air pump and magnetic valve respectively, so as to preferably realize to sphygmomanometer sleeve bag Automatic inflating and exhaust, and then be conducive to the realization of blood pressure information automatic data collection;In addition, between air pump and splitter air inlet pipe also Provided with pressure regulating unit, pressure regulating unit can be stablized to the charge air flow at sphygmomanometer sleeve bag, and this causes right When blood pressure information is acquired, can preferably it realize to the homogenous charge at sphygmomanometer sleeve bag, so that pressure sensor Accurately the blood pressure information of measurement object can be acquired in aeration phase, and then greatly improve gathered blood pressure letter The accuracy and efficiency of breath.
In the present embodiment, the stream pressure that pressure sensor is used at measurement branches device cavity, and pressure sensor output Signal through the first signal condition unit handle after be uploaded to first processing units.
In the present embodiment, magnetic valve can be connected by rubber tube with corresponding splitter escape pipe, consequently facilitating setting.
In the present embodiment, first processing units can accordingly drive according to the blood pressure situation of measurement object, timing controlled Circuit drives air pump is run, and enables to air pump evenly to be inflated into sphygmomanometer sleeve bag by adjusting pressure regulating unit And certain value is reached, in gas replenishment process, pressure sensor preferably can be acquired to the blood pressure information of measurement object;Together When, the blood pressure signal gathered can be converted into electric signal and be sent to the first signal condition unit by pressure sensor;First Signal condition unit includes pre-amplifier unit, filter unit and two grades of amplifying units, so as to be exported to pressure sensor Signal carry out two grades amplification and filter, and then can preferably to pressure sensor export signal remove disturb.Afterwards, exist When being measured, first processing units are run by corresponding drive circuit drive magnetic valve, so as to preferably realize to blood The automatic Rapid degassing of pressure meter sleeve bag.
In the present embodiment, pressure sensor uses piezoelectric transducer, and pressure regulating unit uses flow valve.
In addition, volume pulsation wave acquisition module 110 turns including pulse transducer, secondary signal conditioning unit and the 2nd A/D Block is changed the mold, pulse transducer is used to gather the volume pulsation wave of measurement object and is converted into electric signal, secondary signal conditioning unit Electric signal after for being changed to pulse transducer is amplified, filtered, and the 2nd A/D modular converters are used to adjust through secondary signal Analog signal after reason cell processing is converted into the photoplethysmographic of digital signal form.
With reference to shown in Fig. 4, pulse transducer includes illuminating module and light receiving unit, and illuminating module is used for measurement object Measurement point emission measurement light beam, light receiving unit is used to receive the optical signal of measuring beam reflected light at measurement object simultaneously Be converted to electric signal;Illuminating module includes red emission pipe 111 and near infrared emission pipe 112, red emission pipe 111 and near-infrared Transmitting tube 112 is used under the driving of one second driver element distinguish emission measurement light beam successively, the second driver element control letter Number produced by second processing unit;Light receiving unit includes photoelectric receiving tube 113, and photoelectric receiving tube 113 is used for red emission The reflected light signal of pipe 111 and near infrared emission pipe 112, which is converted to, is sent to secondary signal conditioning unit after electric signal.
In the present embodiment, volume pulsation wave acquisition module 110 also includes a pulse folder, red emission pipe 111, near-infrared Transmitting tube 112 and photoelectric receiving tube 113 are enable to preferably by pulse transducer located at measurement at pulse folder Multiple positions of object, such as finger tip, ear-lobe, forehead, wrist.In addition, the clamping power of the pulse folder in the present embodiment can Automatically adjusted, and then caused by second processing unit, second processing unit can be according to measurement object pulse signal It is strong and weak to realize and the laminating degree of pulse transducer and measurement object is adjusted automatically by the elastic of regulation pulse folder, this Allowing for pulse transducer, more quickly and accurately the volume pulsation wave of measurement object can be adjusted.
In the present embodiment, red emission pipe 111, near infrared emission pipe 112 and photoelectric receiving tube 113 together constitute reflection The pulse transducer of formula, pulse transducer can by the measure to reflected light light intensity indirect gain volume pulsation wave ripple Shape, is sent to second processing unit by the processing of secondary signal conditioning unit afterwards, so as to preferably realize to volume arteries and veins Fight the collection and processing of ripple.
In the present embodiment, volume pulsation wave acquisition module 110 can pass through second when being acquired to volume pulsation wave Processing unit sends control signal to the second driver element, so that red emission pipe 111 and near infrared emission pipe 112 can Emission measurement light beam successively, among these, the second driver element include being respectively used to driving red emission pipe 111 and near infrared emission The drive circuit of pipe 112;Afterwards, photoelectric receiving tube 113 can receive optical signal that measurement object reflected measuring beam simultaneously Electric signal is converted to, the electric signal is original photoplethysmographic signal, the original photoplethysmographic signal It is more faint and for analog signal;Afterwards, original photoplethysmographic signal can enter at secondary signal conditioning unit Two grades of amplifications of row and filtering, so as to obtain the photoplethysmographic that intensity is larger, interference is smaller and more smooth;In addition Afterwards, the analog signal after the processing of secondary signal conditioning unit can be converted to data signal and sent by the 2nd A/D modular converters Second processing unit is given, so that second processing unit can preferably obtain photoplethysmographic signal.
In the present embodiment, second processing unit includes calculating analytic unit, and calculating analytic unit can be calculated using existing Method/functional module is handled the photoplethysmographic received, so as to extract in photoplethysmographic Multiple characteristic points and then calculating is fitted to the plurality of characteristic point, so as to preferably set up volume pulsation wave characteristic point with Correlation models between blood pressure parameter, i.e. blood pressure parameter measurement model.
In the present embodiment, blood pressure parameter measurement model is set up according to langbobier law.
In addition, the blood pressure self-operated measuring unit based on the present embodiment, the present embodiment additionally provides a kind of based on digital control Blood pressure method for automatic measurement, it comprises the following steps:
(1) volume pulsation wave at measurement object arteria brachialis is gathered by volume pulsation wave acquisition module 110 and be converted into The photoplethysmographic of digital signal form;
(2) multiple characteristic points of photoplethysmographic are extracted using second processing unit, and to the plurality of characteristic point Calculation process is fitted, and then sets up out blood pressure parameter measurement model;
(3) use the blood pressure information of the timing acquiring measurement object of blood pressure acquisition module 120 and be converted into data signal, afterwards The data signal exported by first processing units to blood pressure acquisition module 120 handled with obtain mean pressure, systolic pressure and Diastolic pressure;
(4) data sent by second processing unit according to first processing units are carried out to going out blood pressure parameter measurement model Fitting correction.
In the present embodiment, in step (2), computing is fitted to the multiple characteristic point according to Beer-Lambert Law.
In the present embodiment, the data at second processing unit are stored using a memory cell, it is single using a display The data that member is exported to second processing unit are shown.
With reference to shown in Fig. 4, automatic, continuous blood is carried out to measurement object using the blood pressure self-operated measuring unit of the present embodiment During pressure measurement, it can be pressed from both sides first by sphygmomanometer sleeve bag at the upper arm arteria brachialis of measurement object while setting pulse, in order to Hydrostatic pressing is eliminated, also should be guaranteed that measurement object level lies low or arm is placed in parallel and is located at same level with heart;It Afterwards, volume pulsation wave acquisition module 110 is at working condition, so that the volume pulsation wave of measurement object is handled, And blood pressure parameter measurement model is set up out by second processing unit;Meanwhile, it is also single by the first processing during continuous measurement The blood pressure information of the timing acquiring measurement object of member control blood pressure acquisition module 120 is simultaneously sent to second processing unit, so that Second processing unit periodically can be corrected to blood pressure parameter measurement model.
In the present embodiment, a cycle of operation of blood pressure acquisition module 120 is as follows:First, first processing units control is passed through Magnetic valve cut-off processed;Afterwards, control air pump to run by first processing units, and control air pump slow by pressure regulating unit Equably to the linear inflation of sphygmomanometer sleeve bag, so that gradually the upper arm to measurement object pressurizes;In gas replenishment process, pressure sensing Device is operated and gathers the stream pressure at splitter cavity, and the signal that pressure sensor is exported is through the first signal condition list First processing units are uploaded to after member processing, the blood pressure that first processing units go out measurement object according to the signal of change received is joined Number (including mean pressure, systolic pressure and diastolic pressure) is simultaneously sent to second processing unit;Afterwards, certain value is pumped into air pump (to be enough Ensure pressure sensor complete detection) gas after, by first processing units control air pump close, magnetic valve open so that Discharge the gas in sphygmomanometer sleeve bag.Blood pressure acquisition module 120 repeats above-mentioned action when next timing length is reached.
In the present embodiment, the timing controlled to blood pressure acquisition module 120 can be realized by first processing units.
Schematical above that the present invention and embodiments thereof are described, the description does not have restricted, institute in accompanying drawing What is shown is also one of embodiments of the present invention, and actual structure is not limited thereto.So, if the common skill of this area Art personnel are enlightened by it, without departing from the spirit of the invention, are designed and the technical scheme without creative Similar frame mode and embodiment, all should belong to protection scope of the present invention.

Claims (10)

1. based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Including,
Volume pulsation wave acquisition module (110), it is used for the volume pulsation wave for gathering measurement object, and the volume arteries and veins to being gathered Ripple of fighting is handled to obtain photoplethysmographic;
Blood pressure acquisition module (120), it is used for the blood pressure information of timing acquiring measurement object, and the blood pressure information gathered is entered Row handles to obtain blood pressure data signal;And
Processing module, it includes first processing units and second processing unit, and second processing unit is used to extract photoelectricity volume Multiple characteristic points of pulse wave simultaneously set up blood pressure parameter measurement model, and first processing units are used for blood pressure digital signal reception simultaneously Second processing unit is sent to after processing to be timed correction to blood pressure parameter measurement model.
2. according to claim 1 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Second processing list The display unit for the memory cell of data storage and for data output is provided with member.
3. according to claim 1 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Blood pressure gathers mould It is single that block (120) includes pressure generating unit, pressure unit, pressure sensor, the first signal condition unit and the first A/D conversions Member, pressure generating unit is used to provide pressure source to pressure unit, and pressure unit is used to apply to the measurement point of measurement object Pressure, pressure sensor is used for the blood pressure information for gathering measurement object, and the first signal condition unit is used for pressure sensor institute The signal of collection is amplified, filtered, and the first A/D converting units are used to turn the signal after handling through the first signal condition unit Change data signal into and be sent to processing module.
4. according to claim 3 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Pressure produces single Member includes air pump, and pressure unit includes sphygmomanometer sleeve bag, and air pump is used to be pumped into sphygmomanometer sleeve bag at gas, sphygmomanometer sleeve bag Being additionally provided with one is used for the magnetic valve that gas is discharged, and air pump and magnetic valve drive by one first driver element, the first driver element Control signal produced by first processing units.
5. according to claim 4 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Sphygmomanometer sleeve bag Place is provided with a splitter, and splitter includes splitter cavity and the 1 splitter air inlet pipe connected with branch cavity, 3 branches Device escape pipe, the gas outlet access tributary device air inlet pipe of air pump, 3 splitter escape pipes be respectively used to set magnetic valve, Pressure sensor and access sphygmomanometer sleeve bag are set.
6. according to claim 1 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Volume pulsation wave Acquisition module (110) includes pulse transducer, secondary signal conditioning unit and the 2nd A/D modular converters, and pulse transducer is used for Gather the volume pulsation wave of measurement object and be converted into electric signal, secondary signal conditioning unit is used for after being changed to pulse transducer Electric signal be amplified, filter, the 2nd A/D modular converters be used for by through secondary signal conditioning unit handle after analog signal It is converted into the photoplethysmographic of digital signal form.
7. according to claim 6 be based on numerically controlled blood pressure self-operated measuring unit, it is characterised in that:Pulse transducer Including illuminating module and light receiving unit, illuminating module is used for the measurement point emission measurement light beam to measurement object, light-receiving Unit is used to receiving measuring beam the optical signal of reflected light and is converted to electric signal at measurement object;Illuminating module includes feux rouges Transmitting tube (111) and near infrared emission pipe (112), red emission pipe (111) and near infrared emission pipe (112) are used for one second Emission measurement light beam is distinguished under the driving of driver element successively, the second driver element control signal is produced by second processing unit; Light receiving unit includes photoelectric receiving tube (113), and photoelectric receiving tube (113) is used to send out red emission pipe (111) and near-infrared The reflected light signal for penetrating pipe (112) is converted to secondary signal conditioning unit is sent to after electric signal.
8. based on numerically controlled blood pressure method for automatic measurement, it comprises the following steps:
(1) volume pulsation wave at measurement object arteria brachialis is gathered by volume pulsation wave acquisition module (110) and is converted into number The photoplethysmographic of word signal form;
(2) multiple characteristic points of photoplethysmographic are extracted using second processing unit, and the plurality of characteristic point is carried out Fitting operation processing, and then set up out blood pressure parameter measurement model;
(3) use the blood pressure information of blood pressure acquisition module (120) timing acquiring measurement object and be converted into data signal, Zhi Houtong Cross the data signal that first processing units export to blood pressure acquisition module (120) handled with obtain mean pressure, systolic pressure and Diastolic pressure;
(4) data sent by second processing unit according to first processing units are fitted to going out blood pressure parameter measurement model Correction.
9. according to claim 8 be based on numerically controlled blood pressure method for automatic measurement, it is characterised in that:In step (2), Computing is fitted to the multiple characteristic point according to Beer-Lambert Law.
10. according to claim 8 be based on numerically controlled blood pressure method for automatic measurement, it is characterised in that:Deposited using one Storage unit is stored to the data at second processing unit, and the data exported using a display unit to second processing unit are entered Row display.
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