CN102657525B - Nondestructive detection system and method of cardiac function - Google Patents
Nondestructive detection system and method of cardiac function Download PDFInfo
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Abstract
The invention provides a nondestructive detection system and a nondestructive detection method of a cardiac function. The nondestructive detection system of the cardiac function mainly comprises a central control computer, and an electrocardiography signal acquisition module, a heart sound signal acquisition module and a thoracic impedance acquisition module which are in data communication with the central control computer to acquire an electrocardiography signal, a heart sound signal and a thoracic impedance signal respectively, wherein related physiological and pathological characteristic parameters are obtained from the electrocardiography signal, the heart sound signal and the thoracic impedance signal through comprehensive processing of the central control computer, and further related index parameters of the cardiac function are obtained and displayed in real time. The nondestructive detection system and the nondestructive detection method of the cardiac function have higher detection accuracy; the clinical applicability of the nondestructive detection system and the nondestructive detection method is improved; the technical blank that effective nondestructive detection related equipment of the cardiac function is not available yet at present in China; rich operation and remote functions can be realized by combining the conventional computer technology and network technology, and the nondestructive detection system and the nondestructive detection method have excellent application prospect.
Description
Technical field
The present invention relates to biomedical engineering technology and technical field of information processing, particularly a kind of cardiac function noinvasive detection system and method.
Background technology
Reflect that the hemodynamics monitoring of power aroused in interest is for for many years clinical.The monitoring of hemodynamic parameter, much extremely valuable parameter informations can be provided, such as cardiac pumping function index parameter, cardiac systolic function index parameter, index of cardiovascular performance parameter etc., the index parameter that these cardiac function are relevant all has important clinical meaning to medical treatment and scientific research.Along with clinical medical development, various hemodynamics detection methods are arisen at the historic moment.At present, the method of hemodynamic examination is mainly divided into two large classes: the first kind is for there being wound detection method, it is traditional detection method, mainly contain Swan-Ganz tremie method, pulse is indicated continuous cardiac output technology, but owing to there being wound detection method to have wound Data Detection to patient, not only to patient, bring health wound, and the somewhat expensive that has wound to detect, to testing staff's operating technology, require also higher, also need professional to explain Clinical detection data, and the expense that hospital collects from patient there often has wound testing cost far below cardiac function, therefore hematodinamics has the clinical practice of wound detection method to be difficult to popularize, Equations of The Second Kind is noinvasive detection method, comprise carbon dioxide heart stroke algoscopy, doppler ultrasound and breast impedance method, the ICG parameter of its mesothorax impedance method is to heart failure, hypertension, the patients such as dyspnea have good using value, can allow more Accurate Diagnosis of doctor, control risk, select best clinical treatment, improve patient's prognosis, and can not bring traumatic pain to patient, testing cost is also relatively low, particularly there iing the out of use occasion of wound method, as critical patient, light patient, conduit taboo patient and Healthy People, breast impedance method is a kind of desirable detection method.Yet, domesticly at present according to breast impedance method, realize checkout equipment that hematodinamics noinvasive detects in clinical practice also seldom, trace it to its cause, be that the Clinical detection precision of the method is not also accepted by numerous doctors.Therefore, be necessary the cardiac function noinvasive checkout equipment based on breast impedance method further to further investigate, improve its clinical practice precision, realize the extensive use of cardiac function noinvasive checkout equipment.
Summary of the invention
For prior art above shortcomings, the object of the present invention is to provide a kind of cardiac function noinvasive detection system, to reduce the testing cost of cardiac function index of correlation parameter, the clinical applicability that raising cardiac function noinvasive detects, solving hemodynamic parameter in prior art has the problem that wound testing cost is high, clinical applicability is poor, makes up the domestic technology vacancy that not yet occurs effective cardiac function noinvasive detection relevant device at present.
For achieving the above object, the present invention has adopted following technological means:
A cardiac function noinvasive detection system, comprises middle control computer and the ecg signal acquiring module being connected with middle control computer data communication, heart sound signal acquisition module and breast impedance collection module;
Described ecg signal acquiring module is for gathering the electrocardiosignal of detected object;
Described heart sound signal acquisition module is for gathering the cardiechema signals of detected object;
Described breast impedance collection module is for gathering the thoracic impedance signal of detected object;
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model in described middle control computer, have been pre-seted, described ECG Signal Analysis model is for analyzing the electrocardiosignal of detected object, export corresponding electrocardiosignal characteristic parameter, described electrocardiosignal characteristic parameter comprises position that P point in electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval, described analysis of PCG Signal model, for the cardiechema signals of detected object is analyzed, is exported corresponding cardiechema signals characteristic parameter, and described cardiechema signals characteristic parameter comprises width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound, described thoracic impedance signal analytical model, for the thoracic impedance signal of detected object is analyzed, is exported corresponding thoracic impedance signal characteristic parameter, and described thoracic impedance signal characteristic parameter comprises the position that A point in thoracic impedance signal, B point, C point, X point and O are ordered, described parameters of left ventricular function function model is for obtaining the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function according to described electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter, described middle control computer can be by communicating with the ecg signal acquiring module of connection, the electrocardiosignal of heart sound signal acquisition module and breast impedance collection module synchronous acquisition detected object, cardiechema signals and thoracic impedance signal, by the electrocardiosignal of synchronous acquisition, cardiechema signals and thoracic impedance signal are respectively as ECG Signal Analysis model, the input of analysis of PCG Signal model and thoracic impedance signal analytical model, again by ECG Signal Analysis model, the electrocardiosignal characteristic parameter of analysis of PCG Signal model and the output of thoracic impedance signal analytical model, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter are as the input of parameters of left ventricular function function model, obtain the cardiac pumping function of detected object, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.
In above-mentioned cardiac function noinvasive detection system, as a kind of can selection scheme, described breast impedance collection module is mainly by control circuit, exciting current circuit for generating, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuits with amplify modulate circuits and form; Described control circuit is electrically connected to exciting current circuit for generating, and carry out data communication with middle control computer and be connected, control circuit is used for receiving the breast impedance collection control signal from control computer, and controls exciting current circuit for generating generation stimulating current according to breast impedance collection control signal; Described exciting current circuit for generating is also electrically connected to four exciting electrodes by activation fragment buffer circuit, for producing stimulating current and act on human body by four exciting electrodes under the control of control circuit; Two acquisition electrodes in described four acquisition electrodes are used for being arranged on human chest xiphoid-process place, and another two acquisition electrodes are used for being arranged on human body neck root both sides, to gather stimulating current, act on the voltage signal after human body; Two exciting electrodes in described four exciting electrodes are for being separately positioned on the 3cm place, below of two the acquisition electrode setting positions in human chest xiphoid-process place, and another two exciting electrodes are for being separately positioned on the 3cm place, top of two the acquisition electrode setting positions in human body neck root both sides; Amplifying modulate circuit is electrically connected to four acquisition electrodes by capture segment buffer circuit, and carry out data communication with middle control computer and be connected, after amplifying modulate circuit and the voltage signal of four acquisition electrode collections can being amplified, conversion process be thoracic impedance signal and export middle control computer to.
In above-mentioned cardiac function noinvasive detection system, as further improvement project, in described middle control computer, also preset and be equipped with individual of sample information database and individual penalty function model, described individual information data base is for storing the individual information of the detected object of typing, and described individual penalty function model is for recording the Function Mapping relation of cardiac pumping function index parameter, cardiac systolic function index parameter and the offset of index of cardiovascular performance parameter and the individual information of detected object; Middle control computer can be using the individual information of detected object as individual penalty function input and obtain the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter, utilize described offset respectively the cardiac pumping function index parameter of corresponding detected object, cardiac systolic function index parameter and index of cardiovascular performance parameter to be compensated and corrected, obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of the detected object revised, and show in real time.
Correspondingly, the present invention also provides a kind of cardiac function noinvasive detection method, and the present invention has adopted following technological means for this reason:
A cardiac function noinvasive detection method, specifically comprises the following steps:
A) in middle control computer, set in advance ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model; Described ECG Signal Analysis model is for analyzing the electrocardiosignal of detected object, export corresponding electrocardiosignal characteristic parameter, described electrocardiosignal characteristic parameter comprises position that P point in electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Described analysis of PCG Signal model, for the cardiechema signals of detected object is analyzed, is exported corresponding cardiechema signals characteristic parameter, and described cardiechema signals characteristic parameter comprises width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Described thoracic impedance signal analytical model, for the thoracic impedance signal of detected object is analyzed, is exported corresponding thoracic impedance signal characteristic parameter, and described thoracic impedance signal characteristic parameter comprises the position that A point in thoracic impedance signal, B point, C point, X point and O are ordered; Described parameters of left ventricular function function model is for obtaining the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function according to described electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter;
B) electrocardiosignal, cardiechema signals and the thoracic impedance signal by the ecg signal acquiring module, heart sound signal acquisition module and the breast impedance collection module synchronous acquisition detected object that are connected with middle control computer data communication transfer to middle control computer;
C) in, control computer is by the electrocardiosignal of synchronous acquisition, cardiechema signals and thoracic impedance signal are respectively as ECG Signal Analysis model, the input of analysis of PCG Signal model and thoracic impedance signal analytical model, again by ECG Signal Analysis model, the electrocardiosignal characteristic parameter of analysis of PCG Signal model and the output of thoracic impedance signal analytical model, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter are as the input of parameters of left ventricular function function model, obtain the cardiac pumping function of detected object, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.
In above-mentioned cardiac function noinvasive detection method, as further improvement project, in described steps A) in, individual of sample information database and individual penalty function model in middle control computer, have also been set in advance, described individual information data base is for storing the individual information of the detected object of typing, and described individual penalty function model is for recording the Function Mapping relation of cardiac pumping function index parameter, cardiac systolic function index parameter and the offset of index of cardiovascular performance parameter and the individual information of detected object, at described step C) in, middle control computer is resolved the cardiac pumping function that obtains detected object, after the index parameter of cardiac systolic function and cardiovascular function, the also input using the individual information of detected object as individual penalty function and obtain cardiac pumping function index parameter, the offset of cardiac systolic function index parameter and index of cardiovascular performance parameter, utilize the described offset cardiac pumping function index parameter to corresponding detected object respectively, cardiac systolic function index parameter and index of cardiovascular performance parameter compensate and correct, obtain the cardiac pumping function of the detected object of correction, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.
Compared to existing technology, the present invention has following beneficial effect:
1, cardiac function noinvasive detection system of the present invention is utilized multi-signal parameter acquisition module, realize the synchronous acquisition of different physiology, pathological signals, on the breast impedance method basis of existing maturation, improve cardiac function noinvasive and detected comprehensive and reasonability, thereby make cardiac function noinvasive detection system of the present invention there is higher accuracy of detection, improve its clinical applicability, made up the domestic technology vacancy that not yet occurs effective cardiac function noinvasive detection relevant device at present.
2, cardiac function noinvasive detection system of the present invention can adopt the computing technique of technology maturation and circuit module technique construction to form, simple in structure, cost is low, structure is convenient, greatly reduces its testing cost and clinical practice difficulty.
3, cardiac function noinvasive detection system of the present invention be take the processing core that computer is cardiac function testing result, can realize the storage of detected object data, the functions such as the demonstration of cardiac function testing result, printing, and can build data base management system's (for example HIS system) manages, can also share data or realize remote detection and the consultation of doctors by networking and hospital information system, there is good application prospect.
4, cardiac function noinvasive detection method of the present invention has adopted the analytical model based on multiparameter to obtain multiple cardiac function index of correlation parameter, the cardiac function testing result that noinvasive is obtained reflects that cardiac function is with the situation of change of multiple physiology, pathological signals parameter more comprehensively, has avoided the unsettled defect of single parameter cardiac function noinvasive detection method testing result.
5, as further improvement project, cardiac function noinvasive detection method of the present invention is also introduced individual penalty function model, with the individual information by detected object, obtain the offset of cardiac function index of correlation parameter, cardiac function testing result to detected object compensates and corrects, further make up the impact of individual variation on cardiac function testing result, made the method there is better clinical applicability and robustness.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of cardiac function noinvasive detection system of the present invention;
Fig. 2 is the FB(flow block) of cardiac function noinvasive detection method of the present invention;
Fig. 3 is the FB(flow block) of cardiac function noinvasive detection method improvement project of the present invention.
The specific embodiment
Below in conjunction with drawings and Examples, technical scheme of the present invention is described further:
As shown in Figure 1, cardiac function noinvasive detection system of the present invention mainly by control computer and the multi-signal parameter acquisition module composition that is connected with middle control computer data communication, utilize these signal parameter acquisition modules to realize the synchronous acquisition of different physiology, pathological signals; These signal parameter acquisition modules comprise ecg signal acquiring module, heart sound signal acquisition module and breast impedance collection module, for gathering electrocardiosignal, cardiechema signals and thoracic impedance signal and transfer to control computer respectively, the integrated treatment of calculating by middle control, by electrocardiosignal, cardiechema signals and thoracic impedance signal, obtain relevant physiology, pathological characters parameter, and then obtain the index parameter that cardiac function is relevant, and show in real time.
Ecg signal acquiring module mainly consists of three lead electrocardioelectrode and electrocardiosignal amplifying circuits, for gathering electrocardiosignal; Its circuit forms with ECG signal sampling instrument signals collecting circuit structure is partly basic identical on the market, belongs to the circuit structure of technology maturation.
Heart sound signal acquisition module mainly consists of heart sound transducer and cardiechema signals amplifying circuit, for gathering cardiechema signals.Heart sound transducer and cardiechema signals amplifying circuit used in practical application can be ripe heart sound transducer product and signal amplification circuit module of application.
Breast impedance collection module adopts self-control circuit to realize, for gathering patient chest impedance signal; Breast impedance collection module mainly consists of control circuit, exciting current circuit for generating, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuits and amplification modulate circuits; Control circuit is electrically connected to exciting current circuit for generating, and carry out data communication with middle control computer and be connected, control circuit is for receiving the breast impedance collection control signal from control computer, and according to breast impedance collection control signal, control exciting current circuit for generating and produce stimulating current, stimulating current is generally the weak current that 40KHz ~ 120KHz, amplitude were less than/equaled 4mA; Exciting current circuit for generating is also electrically connected to four exciting electrodes by activation fragment buffer circuit, for producing stimulating current and act on human body by four exciting electrodes under the control of control circuit; Two acquisition electrodes in four acquisition electrodes are used for being arranged on human chest xiphoid-process place, and another two acquisition electrodes are used for being arranged on human body neck root both sides, to gather stimulating current, act on the voltage signal after human body; Two exciting electrodes in described four exciting electrodes are for being separately positioned on the 3cm place, below of two the acquisition electrode setting positions in human chest xiphoid-process place, and another two exciting electrodes are for being separately positioned on the 3cm place, top of two the acquisition electrode setting positions in human body neck root both sides; Amplifying modulate circuit is electrically connected to four acquisition electrodes by capture segment buffer circuit, and carry out data communication with middle control computer and be connected, after amplifying modulate circuit and the voltage signal of four acquisition electrode collections can being amplified, conversion process be thoracic impedance signal and export middle control computer to.
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model in middle control computer, have been pre-seted, ECG Signal Analysis model is for analyzing the electrocardiosignal of detected object, export corresponding electrocardiosignal characteristic parameter, described electrocardiosignal characteristic parameter comprises position that P point in electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval, analysis of PCG Signal model, for the cardiechema signals of detected object is analyzed, is exported corresponding cardiechema signals characteristic parameter, and described cardiechema signals characteristic parameter comprises width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound, thoracic impedance signal analytical model, for the thoracic impedance signal of detected object is analyzed, is exported corresponding thoracic impedance signal characteristic parameter, and described thoracic impedance signal characteristic parameter comprises the position that A point in thoracic impedance signal, B point, C point, X point and O are ordered, when thoracic impedance signal is analyzed, can also be as a reference point with Q point position in electrocardiosignal, amplitude maximum in conjunction with first heart sound in cardiechema signals and second heart sound carries out auxiliary positioning to the position that in thoracic impedance signal, A point, B point, C point, X point and O are ordered, the location positioning degree of accuracy of ordering further to improve A point, B point, C point, X point and O, above-mentioned these electrocardiosignal characteristic parameters, cardiechema signals characteristic parameter, thoracic impedance signal characteristic parameter have clear and definite definition in the pertinent literature of medical domain and teaching material, no longer its concrete medical science implication are carried out to repetition of explanation herein, parameters of left ventricular function function model is for obtaining the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function according to described electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter, middle control computer can be by communicating with the ecg signal acquiring module of connection, the electrocardiosignal of heart sound signal acquisition module and breast impedance collection module synchronous acquisition detected object, cardiechema signals and thoracic impedance signal, by the electrocardiosignal of synchronous acquisition, cardiechema signals and thoracic impedance signal are respectively as ECG Signal Analysis model, the input of analysis of PCG Signal model and thoracic impedance signal analytical model, again by ECG Signal Analysis model, the electrocardiosignal characteristic parameter of analysis of PCG Signal model and the output of thoracic impedance signal analytical model, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter are as the input of parameters of left ventricular function function model, obtain the cardiac pumping function of detected object, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.The circuit design of middle control computer can adopt the circuit design scheme of existing personal computer completely, if control cost, also can adopt arm processor, dsp processor etc. for the embedded design scheme of core; Multi-channel data acquisition board can be installed as multi-channel data interface on middle control computer, so that synchronous acquisition multi-signal data.
As can be seen here, cardiac function noinvasive detection system of the present invention can adopt the computing technique of technology maturation and circuit module technique construction to form, simple in structure, cost is low, structure is convenient, greatly reduces its testing cost and clinical practice difficulty.Cardiac function noinvasive detection system of the present invention is utilized multi-signal parameter acquisition module, realize the synchronous acquisition of different physiology, pathological signals, on the breast impedance method basis of existing maturation, improve cardiac function noinvasive and detected comprehensive and reasonability, thereby make cardiac function noinvasive detection system of the present invention there is higher accuracy of detection, improve its clinical applicability, made up the domestic technology vacancy that not yet occurs effective cardiac function noinvasive detection relevant device at present; Moreover, cardiac function noinvasive detection system of the present invention be take the processing core that computer is cardiac function testing result, and in conjunction with existing computer technology and network technology, by the further Programming Design to system, can realize the storage of detected object data, the functions such as the demonstration of cardiac function testing result, printing, and can build data base management system's (HIS system) manages, can also share data or realize remote detection and the consultation of doctors by networking and hospital information system, there is good application prospect.
Adopt above-mentioned cardiac function noinvasive detection system, can realize cardiac function noinvasive detection method of the present invention, as shown in Figure 2, concrete steps are as follows for its flow process:
A) in middle control computer, set in advance ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model; Described ECG Signal Analysis model is for analyzing the electrocardiosignal of detected object, export corresponding electrocardiosignal characteristic parameter, described electrocardiosignal characteristic parameter comprises position that P point in electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Described analysis of PCG Signal model, for the cardiechema signals of detected object is analyzed, is exported corresponding cardiechema signals characteristic parameter, and described cardiechema signals characteristic parameter comprises width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Described thoracic impedance signal analytical model, for the thoracic impedance signal of detected object is analyzed, is exported corresponding thoracic impedance signal characteristic parameter, and described thoracic impedance signal characteristic parameter comprises the position that A point in thoracic impedance signal, B point, C point, X point and O are ordered; Described parameters of left ventricular function function model is for obtaining the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function according to described electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter;
B) electrocardiosignal, cardiechema signals and the thoracic impedance signal by the ecg signal acquiring module, heart sound signal acquisition module and the breast impedance collection module synchronous acquisition detected object that are connected with middle control computer data communication transfer to middle control computer;
C) in, control computer is by the electrocardiosignal of synchronous acquisition, cardiechema signals and thoracic impedance signal are respectively as ECG Signal Analysis model, the input of analysis of PCG Signal model and thoracic impedance signal analytical model, again by ECG Signal Analysis model, the electrocardiosignal characteristic parameter of analysis of PCG Signal model and the output of thoracic impedance signal analytical model, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter are as the input of parameters of left ventricular function function model, obtain the cardiac pumping function of detected object, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.
In above-mentioned cardiac function noinvasive detection method, the processing capacity of middle control computer can utilize Visual C++6.0 programming language to realize, processing capacity software operation work in the operating system platforms such as Windows, Linux that programming obtains, to adapt to different client's needs.In the function treatment software of middle control computer, can, specially for these physiology, a synchrodata logging modle of pathological signals structure of above-mentioned synchronous acquisition, realize the synchronous recording of these physiology, pathological signals and unified management; Meanwhile, can, specially for a cardiac function testing result display interface of demonstration structure of cardiac function index of correlation parameter detecting result, to detecting the cardiac function index of correlation parameter detecting result and the coherent signal characteristic parameter that obtain, show.ECG Signal Analysis model in system, analysis of PCG Signal model and thoracic impedance signal analytical model, for analyzing and draw electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter respectively, therefore can be according to these characteristic parameters the data characteristics in signal separately, utilize existing Digital Signal Analysis recognition technology and mathematical modeling technology to be set up.And for the parameters of left ventricular function function model in system, can select suitable patient group as training sample object, from pathology and mechanics angle, utilize ecg signal acquiring module, heart sound signal acquisition module and breast impedance collection module gather the electrocardiosignal of training sample object, cardiechema signals and thoracic impedance signal, utilize the cardiac function index of correlation parameter detecting result that has wound cardiac monitoring device synchronous acquisition training sample object reality being connected with middle control computer data communication simultaneously, due to electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter and cardiac function have closer contacting, therefore, by data mining and analysis identification, extract the electrocardiosignal characteristic parameter of the training sample object of different syndromes, the dependency relation of the variation of cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter respectively and between the variation of cardiac function index of correlation parameter, can determine corresponding cardiac function index of correlation parameter according to characteristic parameter, by mathematical modeling, obtain parameters of left ventricular function function model again, training is set up in the process of parameters of left ventricular function function model, why select wound cardiac monitoring device to gather the cardiac function index of correlation parameter detecting result of training sample object, because than existing non-invasive cardiac function detection method, the existing real changes of cardiac function situation that has wound cardiac monitoring device more can detect exactly training sample object, avoid the deviation of data in modeling to bring irremediable computing deviation to system, with the accuracy that guarantees that cardiac function noinvasive detects.Obtain after ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model, patient for cardiac function to be measured, without there being again wound cardiac function to detect, but by detecting patient's electrocardiosignal, cardiechema signals and thoracic impedance signal, by ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model, carry out multiparameter, multi-faceted comprehensive calculation process, arrive corresponding cardiac function index of correlation parameter detecting result; Because the detection of electrocardiosignal, cardiechema signals and thoracic impedance signal is all noninvasive, thereby realized, the noinvasive of cardiac function is detected, simultaneously, because this detection method has considered multiple physiology, the pathological signals parameter that causes changes of cardiac function, thereby cardiac function noinvasive detection method of the present invention has had higher Clinical detection precision.
As further improvement project, in the processing capacity software of middle control computer, also preset and be equipped with individual of sample information database and individual penalty function model, individual information data base is for storing the individual information of the detected object of typing, and individual penalty function model is for recording the Function Mapping relation of cardiac pumping function index parameter, cardiac systolic function index parameter and the offset of index of cardiovascular performance parameter and the individual information of detected object, the cardiac function noinvasive detection method flow process of this improvement project as shown in Figure 3, at aforementioned cardiac function noinvasive detecting step A) ~ C) basis on, in described steps A) in, in middle control computer, also set in advance individual of sample information database and individual penalty function model, at described step C) in, middle control computer is resolved the cardiac pumping function that obtains detected object, after the index parameter of cardiac systolic function and cardiovascular function, the also input using the individual information of detected object as individual penalty function and obtain cardiac pumping function index parameter, the offset of cardiac systolic function index parameter and index of cardiovascular performance parameter, utilize the described offset cardiac pumping function index parameter to corresponding detected object respectively, cardiac systolic function index parameter and index of cardiovascular performance parameter compensate and correct, obtain the cardiac pumping function of the detected object of correction, the index parameter of cardiac systolic function and cardiovascular function, and show in real time.The individual information of detected object can comprise one or more information in the information such as the sex, age, height, body weight, clinical disease, physical signs of detected object, can need to determine according to actual clinical.Individual penalty function model can be by long-term Clinical detection, diagnostic data, by virtue of experience analyzing Different Individual information obtains the impact of cardiac function index of correlation parameter variation, in order to further to make up the impact of individual variation on cardiac function testing result, make this cardiac function noinvasive detection method there is better clinical applicability and robustness.
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement technical scheme of the present invention, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of claim scope of the present invention.
Claims (3)
1. a cardiac function noinvasive detection system, is characterized in that, comprises middle control computer and the ecg signal acquiring module being connected with middle control computer data communication, heart sound signal acquisition module and breast impedance collection module;
Described ecg signal acquiring module is for gathering the electrocardiosignal of detected object;
Described heart sound signal acquisition module is for gathering the cardiechema signals of detected object;
Described breast impedance collection module is for gathering the thoracic impedance signal of detected object;
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model in described middle control computer, have been pre-seted, described ECG Signal Analysis model is for analyzing the electrocardiosignal of detected object, export corresponding electrocardiosignal characteristic parameter, described electrocardiosignal characteristic parameter comprises position that P point in electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval, described analysis of PCG Signal model, for the cardiechema signals of detected object is analyzed, is exported corresponding cardiechema signals characteristic parameter, and described cardiechema signals characteristic parameter comprises width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound, described thoracic impedance signal analytical model, for the thoracic impedance signal of detected object is analyzed, is exported corresponding thoracic impedance signal characteristic parameter, and described thoracic impedance signal characteristic parameter comprises the position that A point in thoracic impedance signal, B point, C point, X point and O are ordered, described parameters of left ventricular function function model is for obtaining the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function according to described electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter, described middle control computer can be by communicating with the ecg signal acquiring module of connection, the electrocardiosignal of heart sound signal acquisition module and breast impedance collection module synchronous acquisition detected object, cardiechema signals and thoracic impedance signal, by the electrocardiosignal of synchronous acquisition, cardiechema signals and thoracic impedance signal are respectively as ECG Signal Analysis model, the input of analysis of PCG Signal model and thoracic impedance signal analytical model, again by ECG Signal Analysis model, the electrocardiosignal characteristic parameter of analysis of PCG Signal model and the output of thoracic impedance signal analytical model, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter are as the input of parameters of left ventricular function function model, obtain the cardiac pumping function of detected object, the index parameter of cardiac systolic function and cardiovascular function, and show in real time,
The method for building up of described parameters of left ventricular function function model is specially: utilize ecg signal acquiring module, heart sound signal acquisition module and breast impedance collection module gather the electrocardiosignal of training sample object, cardiechema signals and thoracic impedance signal, utilize the cardiac function index of correlation parameter detecting result that has wound cardiac monitoring device synchronous acquisition training sample object reality being connected with middle control computer data communication simultaneously, due to electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter and cardiac function have closer contacting, therefore, by data mining and analysis identification, extract the electrocardiosignal characteristic parameter of the training sample object of different syndromes, the dependency relation of the variation of cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter respectively and between the variation of cardiac function index of correlation parameter, can determine corresponding cardiac function index of correlation parameter according to characteristic parameter, by mathematical modeling, obtain parameters of left ventricular function function model again.
2. cardiac function noinvasive detection system according to claim 1, it is characterized in that, described breast impedance collection module mainly consists of control circuit, exciting current circuit for generating, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuits and amplification modulate circuits; Described control circuit is electrically connected to exciting current circuit for generating, and carry out data communication with middle control computer and be connected, control circuit is used for receiving the breast impedance collection control signal from control computer, and controls exciting current circuit for generating generation stimulating current according to breast impedance collection control signal; Described exciting current circuit for generating is also electrically connected to four exciting electrodes by activation fragment buffer circuit, for producing stimulating current and act on human body by four exciting electrodes under the control of control circuit; Two acquisition electrodes in described four acquisition electrodes are used for being arranged on human chest xiphoid-process place, and another two acquisition electrodes are used for being arranged on human body neck root both sides, to gather stimulating current, act on the voltage signal after human body; Two exciting electrodes in described four exciting electrodes are for being separately positioned on the 3cm place, below of two the acquisition electrode setting positions in human chest xiphoid-process place, and another two exciting electrodes are for being separately positioned on the 3cm place, top of two the acquisition electrode setting positions in human body neck root both sides; Amplifying modulate circuit is electrically connected to four acquisition electrodes by capture segment buffer circuit, and carry out data communication with middle control computer and be connected, after amplifying modulate circuit and the voltage signal of four acquisition electrode collections can being amplified, conversion process be thoracic impedance signal and export middle control computer to.
3. cardiac function noinvasive detection system according to claim 1, it is characterized in that, in described middle control computer, also preset and be equipped with individual of sample information database and individual penalty function model, described individual information data base is for storing the individual information of the detected object of typing, and described individual penalty function model is for recording the Function Mapping relation of cardiac pumping function index parameter, cardiac systolic function index parameter and the offset of index of cardiovascular performance parameter and the individual information of detected object; Middle control computer can be using the individual information of detected object as individual penalty function input and obtain the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter, utilize described offset respectively the cardiac pumping function index parameter of corresponding detected object, cardiac systolic function index parameter and index of cardiovascular performance parameter to be compensated and corrected, obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of the detected object revised, and show in real time.
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